Amino acid dipepetide frequency for Beauveria bassiana (White muscardine disease fungus) (Tritirachium shiotae)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.63AlaAla: 12.63 ± 0.096	1.154AlaCys: 1.154 ± 0.016	5.131AlaAsp: 5.131 ± 0.033	5.6AlaGlu: 5.6 ± 0.043	3.216AlaPhe: 3.216 ± 0.028	6.638AlaGly: 6.638 ± 0.053	2.047AlaHis: 2.047 ± 0.02	4.258AlaIle: 4.258 ± 0.036	4.442AlaLys: 4.442 ± 0.037	8.569AlaLeu: 8.569 ± 0.05	2.194AlaMet: 2.194 ± 0.019	3.107AlaAsn: 3.107 ± 0.027	5.204AlaPro: 5.204 ± 0.044	3.744AlaGln: 3.744 ± 0.03	5.679AlaArg: 5.679 ± 0.038	7.899AlaSer: 7.899 ± 0.045	5.968AlaThr: 5.968 ± 0.037	6.372AlaVal: 6.372 ± 0.041	1.271AlaTrp: 1.271 ± 0.019	2.204AlaTyr: 2.204 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	1.06CysAla: 1.06 ± 0.014	0.233CysCys: 0.233 ± 0.007	0.672CysAsp: 0.672 ± 0.012	0.607CysGlu: 0.607 ± 0.01	0.524CysPhe: 0.524 ± 0.011	0.94CysGly: 0.94 ± 0.016	0.317CysHis: 0.317 ± 0.009	0.669CysIle: 0.669 ± 0.012	0.524CysLys: 0.524 ± 0.01	1.252CysLeu: 1.252 ± 0.02	0.27CysMet: 0.27 ± 0.007	0.428CysAsn: 0.428 ± 0.01	0.651CysPro: 0.651 ± 0.014	0.443CysGln: 0.443 ± 0.011	0.775CysArg: 0.775 ± 0.013	0.865CysSer: 0.865 ± 0.015	0.676CysThr: 0.676 ± 0.013	0.8CysVal: 0.8 ± 0.014	0.197CysTrp: 0.197 ± 0.007	0.328CysTyr: 0.328 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.887AspAla: 5.887 ± 0.038	0.673AspCys: 0.673 ± 0.013	4.943AspAsp: 4.943 ± 0.056	4.737AspGlu: 4.737 ± 0.039	2.191AspPhe: 2.191 ± 0.025	4.67AspGly: 4.67 ± 0.038	1.197AspHis: 1.197 ± 0.016	2.823AspIle: 2.823 ± 0.028	2.68AspLys: 2.68 ± 0.026	4.848AspLeu: 4.848 ± 0.039	1.435AspMet: 1.435 ± 0.018	1.945AspAsn: 1.945 ± 0.021	2.962AspPro: 2.962 ± 0.024	1.792AspGln: 1.792 ± 0.02	3.117AspArg: 3.117 ± 0.032	4.081AspSer: 4.081 ± 0.036	2.964AspThr: 2.964 ± 0.023	3.909AspVal: 3.909 ± 0.03	0.883AspTrp: 0.883 ± 0.013	1.558AspTyr: 1.558 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.881GluAla: 5.881 ± 0.046	0.603GluCys: 0.603 ± 0.012	3.991GluAsp: 3.991 ± 0.034	5.069GluGlu: 5.069 ± 0.048	1.894GluPhe: 1.894 ± 0.024	3.333GluGly: 3.333 ± 0.03	1.402GluHis: 1.402 ± 0.019	2.671GluIle: 2.671 ± 0.024	3.319GluLys: 3.319 ± 0.035	5.252GluLeu: 5.252 ± 0.041	1.502GluMet: 1.502 ± 0.019	2.088GluAsn: 2.088 ± 0.023	2.812GluPro: 2.812 ± 0.031	2.593GluGln: 2.593 ± 0.03	3.816GluArg: 3.816 ± 0.029	4.017GluSer: 4.017 ± 0.034	3.442GluThr: 3.442 ± 0.027	3.278GluVal: 3.278 ± 0.029	0.832GluTrp: 0.832 ± 0.015	1.572GluTyr: 1.572 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	3.287PheAla: 3.287 ± 0.029	0.547PheCys: 0.547 ± 0.011	2.342PheAsp: 2.342 ± 0.026	2.011PheGlu: 2.011 ± 0.021	1.567PhePhe: 1.567 ± 0.022	2.829PheGly: 2.829 ± 0.03	0.854PheHis: 0.854 ± 0.013	1.645PheIle: 1.645 ± 0.022	1.435PheLys: 1.435 ± 0.018	3.297PheLeu: 3.297 ± 0.032	0.771PheMet: 0.771 ± 0.015	1.324PheAsn: 1.324 ± 0.018	1.737PhePro: 1.737 ± 0.02	1.32PheGln: 1.32 ± 0.016	1.929PheArg: 1.929 ± 0.022	2.812PheSer: 2.812 ± 0.027	2.024PheThr: 2.024 ± 0.022	2.387PheVal: 2.387 ± 0.024	0.627PheTrp: 0.627 ± 0.012	1.042PheTyr: 1.042 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	6.174GlyAla: 6.174 ± 0.047	0.864GlyCys: 0.864 ± 0.015	3.926GlyAsp: 3.926 ± 0.029	3.628GlyGlu: 3.628 ± 0.03	2.726GlyPhe: 2.726 ± 0.025	6.632GlyGly: 6.632 ± 0.07	1.754GlyHis: 1.754 ± 0.023	3.427GlyIle: 3.427 ± 0.031	3.461GlyLys: 3.461 ± 0.034	6.087GlyLeu: 6.087 ± 0.036	1.58GlyMet: 1.58 ± 0.023	2.531GlyAsn: 2.531 ± 0.027	3.256GlyPro: 3.256 ± 0.034	2.645GlyGln: 2.645 ± 0.024	4.478GlyArg: 4.478 ± 0.039	5.731GlySer: 5.731 ± 0.049	3.849GlyThr: 3.849 ± 0.034	4.47GlyVal: 4.47 ± 0.045	1.169GlyTrp: 1.169 ± 0.016	2.036GlyTyr: 2.036 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.11HisAla: 2.11 ± 0.023	0.331HisCys: 0.331 ± 0.008	1.445HisAsp: 1.445 ± 0.017	1.309HisGlu: 1.309 ± 0.019	0.871HisPhe: 0.871 ± 0.013	1.875HisGly: 1.875 ± 0.024	0.912HisHis: 0.912 ± 0.018	1.16HisIle: 1.16 ± 0.017	0.915HisLys: 0.915 ± 0.016	2.242HisLeu: 2.242 ± 0.022	0.54HisMet: 0.54 ± 0.011	0.843HisAsn: 0.843 ± 0.014	1.491HisPro: 1.491 ± 0.02	0.967HisGln: 0.967 ± 0.017	1.627HisArg: 1.627 ± 0.02	1.706HisSer: 1.706 ± 0.021	1.194HisThr: 1.194 ± 0.017	1.549HisVal: 1.549 ± 0.021	0.337HisTrp: 0.337 ± 0.009	0.665HisTyr: 0.665 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.219IleAla: 4.219 ± 0.037	0.701IleCys: 0.701 ± 0.013	2.787IleAsp: 2.787 ± 0.028	2.63IleGlu: 2.63 ± 0.029	1.812IlePhe: 1.812 ± 0.023	3.108IleGly: 3.108 ± 0.031	1.126IleHis: 1.126 ± 0.017	2.283IleIle: 2.283 ± 0.026	2.125IleLys: 2.125 ± 0.023	4.236IleLeu: 4.236 ± 0.036	1.028IleMet: 1.028 ± 0.017	1.671IleAsn: 1.671 ± 0.016	2.628IlePro: 2.628 ± 0.024	1.727IleGln: 1.727 ± 0.02	2.647IleArg: 2.647 ± 0.022	3.402IleSer: 3.402 ± 0.03	2.616IleThr: 2.616 ± 0.028	3.138IleVal: 3.138 ± 0.026	0.66IleTrp: 0.66 ± 0.013	1.256IleTyr: 1.256 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.321LysAla: 4.321 ± 0.034	0.48LysCys: 0.48 ± 0.01	2.704LysAsp: 2.704 ± 0.025	3.056LysGlu: 3.056 ± 0.036	1.408LysPhe: 1.408 ± 0.018	2.795LysGly: 2.795 ± 0.026	1.12LysHis: 1.12 ± 0.015	2.128LysIle: 2.128 ± 0.023	3.239LysLys: 3.239 ± 0.049	4.127LysLeu: 4.127 ± 0.034	1.084LysMet: 1.084 ± 0.015	1.667LysAsn: 1.667 ± 0.021	2.655LysPro: 2.655 ± 0.028	1.961LysGln: 1.961 ± 0.022	3.305LysArg: 3.305 ± 0.026	3.388LysSer: 3.388 ± 0.031	2.922LysThr: 2.922 ± 0.03	2.706LysVal: 2.706 ± 0.024	0.64LysTrp: 0.64 ± 0.011	1.294LysTyr: 1.294 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.72LeuAla: 8.72 ± 0.052	1.243LeuCys: 1.243 ± 0.016	5.39LeuAsp: 5.39 ± 0.04	5.222LeuGlu: 5.222 ± 0.043	3.275LeuPhe: 3.275 ± 0.029	6.051LeuGly: 6.051 ± 0.042	2.25LeuHis: 2.25 ± 0.025	3.676LeuIle: 3.676 ± 0.031	3.853LeuLys: 3.853 ± 0.03	8.455LeuLeu: 8.455 ± 0.057	1.784LeuMet: 1.784 ± 0.02	2.89LeuAsn: 2.89 ± 0.027	5.388LeuPro: 5.388 ± 0.038	3.866LeuGln: 3.866 ± 0.036	6.032LeuArg: 6.032 ± 0.037	6.904LeuSer: 6.904 ± 0.046	4.674LeuThr: 4.674 ± 0.038	5.757LeuVal: 5.757 ± 0.041	1.206LeuTrp: 1.206 ± 0.018	2.26LeuTyr: 2.26 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.491MetAla: 2.491 ± 0.023	0.264MetCys: 0.264 ± 0.007	1.304MetAsp: 1.304 ± 0.017	1.254MetGlu: 1.254 ± 0.016	0.705MetPhe: 0.705 ± 0.011	1.47MetGly: 1.47 ± 0.02	0.535MetHis: 0.535 ± 0.011	0.934MetIle: 0.934 ± 0.017	0.971MetLys: 0.971 ± 0.015	1.981MetLeu: 1.981 ± 0.021	0.635MetMet: 0.635 ± 0.012	0.745MetAsn: 0.745 ± 0.014	1.399MetPro: 1.399 ± 0.021	0.947MetGln: 0.947 ± 0.014	1.402MetArg: 1.402 ± 0.018	1.855MetSer: 1.855 ± 0.019	1.413MetThr: 1.413 ± 0.02	1.319MetVal: 1.319 ± 0.018	0.261MetTrp: 0.261 ± 0.008	0.556MetTyr: 0.556 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.165AsnAla: 3.165 ± 0.028	0.422AsnCys: 0.422 ± 0.01	1.964AsnAsp: 1.964 ± 0.023	1.878AsnGlu: 1.878 ± 0.019	1.261AsnPhe: 1.261 ± 0.017	2.946AsnGly: 2.946 ± 0.034	0.829AsnHis: 0.829 ± 0.014	1.847AsnIle: 1.847 ± 0.022	1.588AsnLys: 1.588 ± 0.02	3.058AsnLeu: 3.058 ± 0.023	0.876AsnMet: 0.876 ± 0.015	1.464AsnAsn: 1.464 ± 0.022	2.124AsnPro: 2.124 ± 0.027	1.203AsnGln: 1.203 ± 0.019	1.863AsnArg: 1.863 ± 0.02	2.523AsnSer: 2.523 ± 0.029	2.014AsnThr: 2.014 ± 0.023	2.305AsnVal: 2.305 ± 0.024	0.531AsnTrp: 0.531 ± 0.011	0.965AsnTyr: 0.965 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.755ProAla: 5.755 ± 0.044	0.53ProCys: 0.53 ± 0.011	3.247ProAsp: 3.247 ± 0.027	3.522ProGlu: 3.522 ± 0.029	1.898ProPhe: 1.898 ± 0.02	3.893ProGly: 3.893 ± 0.044	1.277ProHis: 1.277 ± 0.018	2.262ProIle: 2.262 ± 0.024	2.502ProLys: 2.502 ± 0.026	4.608ProLeu: 4.608 ± 0.038	1.094ProMet: 1.094 ± 0.017	1.965ProAsn: 1.965 ± 0.022	5.029ProPro: 5.029 ± 0.073	2.333ProGln: 2.333 ± 0.031	3.485ProArg: 3.485 ± 0.034	5.419ProSer: 5.419 ± 0.053	3.639ProThr: 3.639 ± 0.037	3.605ProVal: 3.605 ± 0.03	0.702ProTrp: 0.702 ± 0.013	1.358ProTyr: 1.358 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.596GlnAla: 3.596 ± 0.035	0.433GlnCys: 0.433 ± 0.01	2.216GlnAsp: 2.216 ± 0.024	2.281GlnGlu: 2.281 ± 0.024	1.253GlnPhe: 1.253 ± 0.017	2.436GlnGly: 2.436 ± 0.025	1.178GlnHis: 1.178 ± 0.018	1.755GlnIle: 1.755 ± 0.021	1.891GlnLys: 1.891 ± 0.021	3.586GlnLeu: 3.586 ± 0.027	0.93GlnMet: 0.93 ± 0.015	1.394GlnAsn: 1.394 ± 0.018	2.472GlnPro: 2.472 ± 0.029	2.782GlnGln: 2.782 ± 0.054	2.84GlnArg: 2.84 ± 0.024	3.006GlnSer: 3.006 ± 0.029	2.273GlnThr: 2.273 ± 0.02	2.308GlnVal: 2.308 ± 0.025	0.546GlnTrp: 0.546 ± 0.011	1.097GlnTyr: 1.097 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.451ArgAla: 5.451 ± 0.039	0.759ArgCys: 0.759 ± 0.013	3.694ArgAsp: 3.694 ± 0.034	3.66ArgGlu: 3.66 ± 0.032	2.171ArgPhe: 2.171 ± 0.024	4.129ArgGly: 4.129 ± 0.042	1.724ArgHis: 1.724 ± 0.023	2.863ArgIle: 2.863 ± 0.025	3.237ArgLys: 3.237 ± 0.03	5.756ArgLeu: 5.756 ± 0.036	1.35ArgMet: 1.35 ± 0.017	2.219ArgAsn: 2.219 ± 0.023	3.562ArgPro: 3.562 ± 0.034	2.807ArgGln: 2.807 ± 0.03	5.669ArgArg: 5.669 ± 0.053	4.706ArgSer: 4.706 ± 0.043	3.224ArgThr: 3.224 ± 0.024	3.556ArgVal: 3.556 ± 0.028	0.937ArgTrp: 0.937 ± 0.015	1.594ArgTyr: 1.594 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	7.167SerAla: 7.167 ± 0.05	0.848SerCys: 0.848 ± 0.015	4.188SerAsp: 4.188 ± 0.038	3.808SerGlu: 3.808 ± 0.032	2.836SerPhe: 2.836 ± 0.027	5.481SerGly: 5.481 ± 0.041	1.851SerHis: 1.851 ± 0.021	3.721SerIle: 3.721 ± 0.031	3.595SerLys: 3.595 ± 0.035	6.87SerLeu: 6.87 ± 0.048	1.721SerMet: 1.721 ± 0.018	2.792SerAsn: 2.792 ± 0.03	5.012SerPro: 5.012 ± 0.054	3.108SerGln: 3.108 ± 0.029	5.007SerArg: 5.007 ± 0.039	8.659SerSer: 8.659 ± 0.09	5.164SerThr: 5.164 ± 0.053	4.579SerVal: 4.579 ± 0.034	1.054SerTrp: 1.054 ± 0.018	1.898SerTyr: 1.898 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.758ThrAla: 5.758 ± 0.036	0.706ThrCys: 0.706 ± 0.013	2.882ThrAsp: 2.882 ± 0.027	3.051ThrGlu: 3.051 ± 0.03	2.11ThrPhe: 2.11 ± 0.024	4.11ThrGly: 4.11 ± 0.043	1.226ThrHis: 1.226 ± 0.016	2.857ThrIle: 2.857 ± 0.029	2.557ThrLys: 2.557 ± 0.026	5.114ThrLeu: 5.114 ± 0.037	1.24ThrMet: 1.24 ± 0.017	1.959ThrAsn: 1.959 ± 0.021	4.138ThrPro: 4.138 ± 0.042	2.017ThrGln: 2.017 ± 0.024	3.212ThrArg: 3.212 ± 0.026	4.972ThrSer: 4.972 ± 0.048	4.44ThrThr: 4.44 ± 0.054	3.784ThrVal: 3.784 ± 0.03	0.814ThrTrp: 0.814 ± 0.014	1.462ThrTyr: 1.462 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	6.222ValAla: 6.222 ± 0.041	0.86ValCys: 0.86 ± 0.014	3.945ValAsp: 3.945 ± 0.032	3.841ValGlu: 3.841 ± 0.031	2.462ValPhe: 2.462 ± 0.023	4.219ValGly: 4.219 ± 0.038	1.425ValHis: 1.425 ± 0.018	2.838ValIle: 2.838 ± 0.027	2.8ValLys: 2.8 ± 0.027	5.772ValLeu: 5.772 ± 0.041	1.402ValMet: 1.402 ± 0.017	2.154ValAsn: 2.154 ± 0.02	3.667ValPro: 3.667 ± 0.046	2.417ValGln: 2.417 ± 0.025	3.648ValArg: 3.648 ± 0.033	4.529ValSer: 4.529 ± 0.032	3.521ValThr: 3.521 ± 0.028	4.655ValVal: 4.655 ± 0.042	0.868ValTrp: 0.868 ± 0.017	1.683ValTyr: 1.683 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.206TrpAla: 1.206 ± 0.019	0.193TrpCys: 0.193 ± 0.006	0.891TrpAsp: 0.891 ± 0.016	0.781TrpGlu: 0.781 ± 0.014	0.516TrpPhe: 0.516 ± 0.011	0.887TrpGly: 0.887 ± 0.014	0.361TrpHis: 0.361 ± 0.009	0.701TrpIle: 0.701 ± 0.012	0.745TrpLys: 0.745 ± 0.012	1.354TrpLeu: 1.354 ± 0.019	0.362TrpMet: 0.362 ± 0.008	0.584TrpAsn: 0.584 ± 0.011	0.622TrpPro: 0.622 ± 0.013	0.596TrpGln: 0.596 ± 0.011	0.978TrpArg: 0.978 ± 0.016	1.031TrpSer: 1.031 ± 0.015	0.879TrpThr: 0.879 ± 0.015	0.857TrpVal: 0.857 ± 0.014	0.27TrpTrp: 0.27 ± 0.008	0.416TrpTyr: 0.416 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.223TyrAla: 2.223 ± 0.023	0.388TyrCys: 0.388 ± 0.01	1.636TyrAsp: 1.636 ± 0.02	1.423TyrGlu: 1.423 ± 0.02	1.094TyrPhe: 1.094 ± 0.014	1.984TyrGly: 1.984 ± 0.023	0.705TyrHis: 0.705 ± 0.012	1.282TyrIle: 1.282 ± 0.018	1.123TyrLys: 1.123 ± 0.014	2.43TyrLeu: 2.43 ± 0.024	0.643TyrMet: 0.643 ± 0.012	1.05TyrAsn: 1.05 ± 0.018	1.312TyrPro: 1.312 ± 0.02	1.003TyrGln: 1.003 ± 0.015	1.56TyrArg: 1.56 ± 0.02	1.854TyrSer: 1.854 ± 0.021	1.515TyrThr: 1.515 ± 0.018	1.594TyrVal: 1.594 ± 0.021	0.426TyrTrp: 0.426 ± 0.01	0.876TyrTyr: 0.876 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10656 proteins (4698728 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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