Amino acid dipepetide frequency for Saliniradius amylolyticus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.78AlaAla: 7.78 ± 0.106
0.965AlaCys: 0.965 ± 0.034
5.34AlaAsp: 5.34 ± 0.076
6.278AlaGlu: 6.278 ± 0.09
3.343AlaPhe: 3.343 ± 0.062
6.513AlaGly: 6.513 ± 0.092
1.827AlaHis: 1.827 ± 0.042
5.461AlaIle: 5.461 ± 0.084
4.119AlaLys: 4.119 ± 0.081
10.315AlaLeu: 10.315 ± 0.139
2.727AlaMet: 2.727 ± 0.061
3.233AlaAsn: 3.233 ± 0.07
3.119AlaPro: 3.119 ± 0.062
4.02AlaGln: 4.02 ± 0.066
4.841AlaArg: 4.841 ± 0.075
5.438AlaSer: 5.438 ± 0.077
4.089AlaThr: 4.089 ± 0.068
6.079AlaVal: 6.079 ± 0.097
0.925AlaTrp: 0.925 ± 0.035
2.566AlaTyr: 2.566 ± 0.054
0.0AlaXaa: 0.0 ± 0.0
Cys
0.723CysAla: 0.723 ± 0.027
0.136CysCys: 0.136 ± 0.011
0.557CysAsp: 0.557 ± 0.027
0.54CysGlu: 0.54 ± 0.024
0.407CysPhe: 0.407 ± 0.023
0.812CysGly: 0.812 ± 0.036
0.336CysHis: 0.336 ± 0.02
0.45CysIle: 0.45 ± 0.022
0.277CysLys: 0.277 ± 0.015
0.957CysLeu: 0.957 ± 0.028
0.189CysMet: 0.189 ± 0.015
0.271CysAsn: 0.271 ± 0.017
0.517CysPro: 0.517 ± 0.022
0.662CysGln: 0.662 ± 0.027
0.558CysArg: 0.558 ± 0.026
0.587CysSer: 0.587 ± 0.026
0.401CysThr: 0.401 ± 0.018
0.591CysVal: 0.591 ± 0.028
0.142CysTrp: 0.142 ± 0.012
0.333CysTyr: 0.333 ± 0.022
0.0CysXaa: 0.0 ± 0.0
Asp
4.905AspAla: 4.905 ± 0.078
0.537AspCys: 0.537 ± 0.025
3.697AspAsp: 3.697 ± 0.063
4.172AspGlu: 4.172 ± 0.087
2.585AspPhe: 2.585 ± 0.059
4.181AspGly: 4.181 ± 0.078
1.197AspHis: 1.197 ± 0.037
3.731AspIle: 3.731 ± 0.066
3.465AspLys: 3.465 ± 0.069
5.073AspLeu: 5.073 ± 0.077
1.654AspMet: 1.654 ± 0.034
2.612AspAsn: 2.612 ± 0.063
2.394AspPro: 2.394 ± 0.052
2.183AspGln: 2.183 ± 0.049
2.673AspArg: 2.673 ± 0.054
3.581AspSer: 3.581 ± 0.063
3.017AspThr: 3.017 ± 0.057
3.872AspVal: 3.872 ± 0.075
1.127AspTrp: 1.127 ± 0.035
2.523AspTyr: 2.523 ± 0.055
0.0AspXaa: 0.0 ± 0.0
Glu
5.778GluAla: 5.778 ± 0.09
0.468GluCys: 0.468 ± 0.024
3.207GluAsp: 3.207 ± 0.065
3.745GluGlu: 3.745 ± 0.084
2.269GluPhe: 2.269 ± 0.059
3.899GluGly: 3.899 ± 0.065
1.807GluHis: 1.807 ± 0.043
3.045GluIle: 3.045 ± 0.064
3.021GluLys: 3.021 ± 0.057
7.476GluLeu: 7.476 ± 0.104
1.575GluMet: 1.575 ± 0.041
2.041GluAsn: 2.041 ± 0.047
2.574GluPro: 2.574 ± 0.058
5.326GluGln: 5.326 ± 0.088
4.127GluArg: 4.127 ± 0.063
3.687GluSer: 3.687 ± 0.07
2.931GluThr: 2.931 ± 0.056
4.686GluVal: 4.686 ± 0.087
0.651GluTrp: 0.651 ± 0.028
1.735GluTyr: 1.735 ± 0.046
0.0GluXaa: 0.0 ± 0.0
Phe
3.331PheAla: 3.331 ± 0.075
0.46PheCys: 0.46 ± 0.023
2.772PheAsp: 2.772 ± 0.053
2.581PheGlu: 2.581 ± 0.065
1.546PhePhe: 1.546 ± 0.048
3.043PheGly: 3.043 ± 0.061
0.842PheHis: 0.842 ± 0.033
2.235PheIle: 2.235 ± 0.056
1.648PheLys: 1.648 ± 0.041
3.143PheLeu: 3.143 ± 0.071
0.905PheMet: 0.905 ± 0.034
1.838PheAsn: 1.838 ± 0.049
1.395PhePro: 1.395 ± 0.041
1.243PheGln: 1.243 ± 0.039
1.819PheArg: 1.819 ± 0.052
2.864PheSer: 2.864 ± 0.061
2.078PheThr: 2.078 ± 0.051
2.584PheVal: 2.584 ± 0.055
0.617PheTrp: 0.617 ± 0.025
1.365PheTyr: 1.365 ± 0.041
0.0PheXaa: 0.0 ± 0.0
Gly
5.669GlyAla: 5.669 ± 0.093
0.822GlyCys: 0.822 ± 0.033
4.245GlyAsp: 4.245 ± 0.073
4.645GlyGlu: 4.645 ± 0.074
3.335GlyPhe: 3.335 ± 0.062
5.117GlyGly: 5.117 ± 0.087
1.787GlyHis: 1.787 ± 0.043
4.309GlyIle: 4.309 ± 0.072
3.681GlyLys: 3.681 ± 0.069
7.636GlyLeu: 7.636 ± 0.095
2.06GlyMet: 2.06 ± 0.039
2.572GlyAsn: 2.572 ± 0.06
2.089GlyPro: 2.089 ± 0.051
3.702GlyGln: 3.702 ± 0.064
3.669GlyArg: 3.669 ± 0.063
4.107GlySer: 4.107 ± 0.07
3.312GlyThr: 3.312 ± 0.076
5.23GlyVal: 5.23 ± 0.079
1.085GlyTrp: 1.085 ± 0.039
2.549GlyTyr: 2.549 ± 0.061
0.0GlyXaa: 0.0 ± 0.0
His
1.602HisAla: 1.602 ± 0.041
0.354HisCys: 0.354 ± 0.02
1.155HisAsp: 1.155 ± 0.032
1.179HisGlu: 1.179 ± 0.039
1.116HisPhe: 1.116 ± 0.028
1.712HisGly: 1.712 ± 0.048
0.747HisHis: 0.747 ± 0.032
1.335HisIle: 1.335 ± 0.041
1.099HisLys: 1.099 ± 0.033
2.569HisLeu: 2.569 ± 0.055
0.504HisMet: 0.504 ± 0.022
0.843HisAsn: 0.843 ± 0.029
1.39HisPro: 1.39 ± 0.038
1.58HisGln: 1.58 ± 0.047
1.468HisArg: 1.468 ± 0.04
1.483HisSer: 1.483 ± 0.04
1.075HisThr: 1.075 ± 0.034
1.179HisVal: 1.179 ± 0.042
0.522HisTrp: 0.522 ± 0.023
1.056HisTyr: 1.056 ± 0.031
0.0HisXaa: 0.0 ± 0.0
Ile
5.22IleAla: 5.22 ± 0.088
0.524IleCys: 0.524 ± 0.023
3.507IleAsp: 3.507 ± 0.063
3.987IleGlu: 3.987 ± 0.065
1.73IlePhe: 1.73 ± 0.055
4.225IleGly: 4.225 ± 0.081
1.224IleHis: 1.224 ± 0.034
2.602IleIle: 2.602 ± 0.062
2.587IleLys: 2.587 ± 0.054
4.729IleLeu: 4.729 ± 0.07
1.167IleMet: 1.167 ± 0.035
2.359IleAsn: 2.359 ± 0.054
2.351IlePro: 2.351 ± 0.049
2.394IleGln: 2.394 ± 0.053
3.018IleArg: 3.018 ± 0.055
3.461IleSer: 3.461 ± 0.064
2.96IleThr: 2.96 ± 0.054
3.403IleVal: 3.403 ± 0.069
0.61IleTrp: 0.61 ± 0.026
1.512IleTyr: 1.512 ± 0.038
0.0IleXaa: 0.0 ± 0.0
Lys
4.77LysAla: 4.77 ± 0.08
0.267LysCys: 0.267 ± 0.026
2.718LysAsp: 2.718 ± 0.057
2.733LysGlu: 2.733 ± 0.064
1.16LysPhe: 1.16 ± 0.034
3.124LysGly: 3.124 ± 0.065
1.165LysHis: 1.165 ± 0.038
1.967LysIle: 1.967 ± 0.044
2.118LysLys: 2.118 ± 0.053
4.879LysLeu: 4.879 ± 0.075
1.07LysMet: 1.07 ± 0.035
1.599LysAsn: 1.599 ± 0.046
2.234LysPro: 2.234 ± 0.052
2.931LysGln: 2.931 ± 0.055
2.733LysArg: 2.733 ± 0.056
2.393LysSer: 2.393 ± 0.054
2.445LysThr: 2.445 ± 0.052
3.455LysVal: 3.455 ± 0.063
0.449LysTrp: 0.449 ± 0.023
1.141LysTyr: 1.141 ± 0.041
0.0LysXaa: 0.0 ± 0.0
Leu
10.529LeuAla: 10.529 ± 0.123
1.072LeuCys: 1.072 ± 0.034
6.278LeuAsp: 6.278 ± 0.085
6.561LeuGlu: 6.561 ± 0.087
4.013LeuPhe: 4.013 ± 0.077
7.232LeuGly: 7.232 ± 0.119
2.211LeuHis: 2.211 ± 0.053
5.499LeuIle: 5.499 ± 0.094
5.24LeuLys: 5.24 ± 0.078
11.012LeuLeu: 11.012 ± 0.152
2.926LeuMet: 2.926 ± 0.063
4.45LeuAsn: 4.45 ± 0.071
5.181LeuPro: 5.181 ± 0.079
4.117LeuGln: 4.117 ± 0.074
4.926LeuArg: 4.926 ± 0.076
7.914LeuSer: 7.914 ± 0.092
6.348LeuThr: 6.348 ± 0.091
7.273LeuVal: 7.273 ± 0.094
1.195LeuTrp: 1.195 ± 0.038
2.876LeuTyr: 2.876 ± 0.061
0.0LeuXaa: 0.0 ± 0.0
Met
2.766MetAla: 2.766 ± 0.057
0.153MetCys: 0.153 ± 0.013
1.506MetAsp: 1.506 ± 0.035
1.428MetGlu: 1.428 ± 0.041
0.671MetPhe: 0.671 ± 0.025
1.883MetGly: 1.883 ± 0.046
0.509MetHis: 0.509 ± 0.024
1.247MetIle: 1.247 ± 0.035
1.21MetLys: 1.21 ± 0.035
2.734MetLeu: 2.734 ± 0.055
0.717MetMet: 0.717 ± 0.029
0.941MetAsn: 0.941 ± 0.029
1.307MetPro: 1.307 ± 0.037
1.343MetGln: 1.343 ± 0.042
1.342MetArg: 1.342 ± 0.035
1.712MetSer: 1.712 ± 0.043
1.704MetThr: 1.704 ± 0.04
1.855MetVal: 1.855 ± 0.043
0.185MetTrp: 0.185 ± 0.014
0.458MetTyr: 0.458 ± 0.019
0.0MetXaa: 0.0 ± 0.0
Asn
3.27AsnAla: 3.27 ± 0.064
0.333AsnCys: 0.333 ± 0.017
2.187AsnAsp: 2.187 ± 0.053
2.11AsnGlu: 2.11 ± 0.052
1.284AsnPhe: 1.284 ± 0.043
2.838AsnGly: 2.838 ± 0.058
0.866AsnHis: 0.866 ± 0.03
2.161AsnIle: 2.161 ± 0.05
1.681AsnLys: 1.681 ± 0.046
3.729AsnLeu: 3.729 ± 0.071
0.852AsnMet: 0.852 ± 0.032
1.496AsnAsn: 1.496 ± 0.044
2.007AsnPro: 2.007 ± 0.048
2.107AsnGln: 2.107 ± 0.049
2.103AsnArg: 2.103 ± 0.046
2.019AsnSer: 2.019 ± 0.046
2.001AsnThr: 2.001 ± 0.045
2.258AsnVal: 2.258 ± 0.049
0.666AsnTrp: 0.666 ± 0.029
1.264AsnTyr: 1.264 ± 0.034
0.0AsnXaa: 0.0 ± 0.0
Pro
3.475ProAla: 3.475 ± 0.069
0.348ProCys: 0.348 ± 0.018
3.067ProAsp: 3.067 ± 0.057
3.967ProGlu: 3.967 ± 0.058
1.671ProPhe: 1.671 ± 0.044
3.114ProGly: 3.114 ± 0.063
0.886ProHis: 0.886 ± 0.032
2.055ProIle: 2.055 ± 0.046
2.021ProLys: 2.021 ± 0.048
4.417ProLeu: 4.417 ± 0.081
1.097ProMet: 1.097 ± 0.033
1.533ProAsn: 1.533 ± 0.042
1.372ProPro: 1.372 ± 0.043
1.937ProGln: 1.937 ± 0.045
1.666ProArg: 1.666 ± 0.049
2.408ProSer: 2.408 ± 0.054
1.895ProThr: 1.895 ± 0.045
3.566ProVal: 3.566 ± 0.065
0.581ProTrp: 0.581 ± 0.028
1.341ProTyr: 1.341 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
5.573GlnAla: 5.573 ± 0.09
0.418GlnCys: 0.418 ± 0.021
2.514GlnAsp: 2.514 ± 0.045
2.64GlnGlu: 2.64 ± 0.061
1.824GlnPhe: 1.824 ± 0.044
3.768GlnGly: 3.768 ± 0.064
1.552GlnHis: 1.552 ± 0.041
2.351GlnIle: 2.351 ± 0.049
2.077GlnLys: 2.077 ± 0.046
5.968GlnLeu: 5.968 ± 0.097
1.311GlnMet: 1.311 ± 0.036
1.627GlnAsn: 1.627 ± 0.045
2.375GlnPro: 2.375 ± 0.056
4.458GlnGln: 4.458 ± 0.094
3.358GlnArg: 3.358 ± 0.062
3.403GlnSer: 3.403 ± 0.064
2.529GlnThr: 2.529 ± 0.048
3.559GlnVal: 3.559 ± 0.069
0.975GlnTrp: 0.975 ± 0.035
1.4GlnTyr: 1.4 ± 0.034
0.0GlnXaa: 0.0 ± 0.0
Arg
4.155ArgAla: 4.155 ± 0.068
0.504ArgCys: 0.504 ± 0.02
2.861ArgAsp: 2.861 ± 0.056
3.327ArgGlu: 3.327 ± 0.061
2.559ArgPhe: 2.559 ± 0.053
2.979ArgGly: 2.979 ± 0.058
1.562ArgHis: 1.562 ± 0.045
3.208ArgIle: 3.208 ± 0.061
2.26ArgLys: 2.26 ± 0.057
6.384ArgLeu: 6.384 ± 0.086
1.324ArgMet: 1.324 ± 0.038
1.836ArgAsn: 1.836 ± 0.049
2.068ArgPro: 2.068 ± 0.045
3.726ArgGln: 3.726 ± 0.062
3.332ArgArg: 3.332 ± 0.072
2.786ArgSer: 2.786 ± 0.054
2.278ArgThr: 2.278 ± 0.051
3.756ArgVal: 3.756 ± 0.065
0.867ArgTrp: 0.867 ± 0.034
1.984ArgTyr: 1.984 ± 0.049
0.0ArgXaa: 0.0 ± 0.0
Ser
5.454SerAla: 5.454 ± 0.079
0.534SerCys: 0.534 ± 0.023
3.731SerAsp: 3.731 ± 0.081
4.21SerGlu: 4.21 ± 0.076
2.385SerPhe: 2.385 ± 0.05
5.185SerGly: 5.185 ± 0.084
1.477SerHis: 1.477 ± 0.04
3.176SerIle: 3.176 ± 0.065
2.384SerLys: 2.384 ± 0.052
6.89SerLeu: 6.89 ± 0.094
1.618SerMet: 1.618 ± 0.04
2.06SerAsn: 2.06 ± 0.055
2.581SerPro: 2.581 ± 0.056
3.349SerGln: 3.349 ± 0.068
3.274SerArg: 3.274 ± 0.057
3.684SerSer: 3.684 ± 0.06
2.753SerThr: 2.753 ± 0.061
4.602SerVal: 4.602 ± 0.07
0.801SerTrp: 0.801 ± 0.028
1.875SerTyr: 1.875 ± 0.043
0.0SerXaa: 0.0 ± 0.0
Thr
4.406ThrAla: 4.406 ± 0.07
0.369ThrCys: 0.369 ± 0.019
3.096ThrAsp: 3.096 ± 0.07
3.237ThrGlu: 3.237 ± 0.068
1.751ThrPhe: 1.751 ± 0.041
4.278ThrGly: 4.278 ± 0.061
1.214ThrHis: 1.214 ± 0.034
2.74ThrIle: 2.74 ± 0.057
1.661ThrLys: 1.661 ± 0.045
6.338ThrLeu: 6.338 ± 0.086
1.046ThrMet: 1.046 ± 0.033
1.718ThrAsn: 1.718 ± 0.045
2.689ThrPro: 2.689 ± 0.052
2.584ThrGln: 2.584 ± 0.056
2.49ThrArg: 2.49 ± 0.051
2.965ThrSer: 2.965 ± 0.058
2.483ThrThr: 2.483 ± 0.05
3.456ThrVal: 3.456 ± 0.061
0.477ThrTrp: 0.477 ± 0.022
1.381ThrTyr: 1.381 ± 0.036
0.0ThrXaa: 0.0 ± 0.0
Val
6.255ValAla: 6.255 ± 0.089
0.663ValCys: 0.663 ± 0.027
4.333ValAsp: 4.333 ± 0.062
4.538ValGlu: 4.538 ± 0.071
2.742ValPhe: 2.742 ± 0.059
4.656ValGly: 4.656 ± 0.073
1.411ValHis: 1.411 ± 0.036
4.055ValIle: 4.055 ± 0.077
3.286ValLys: 3.286 ± 0.071
7.135ValLeu: 7.135 ± 0.089
1.905ValMet: 1.905 ± 0.044
2.813ValAsn: 2.813 ± 0.05
2.759ValPro: 2.759 ± 0.057
2.484ValGln: 2.484 ± 0.049
3.452ValArg: 3.452 ± 0.073
4.892ValSer: 4.892 ± 0.067
4.255ValThr: 4.255 ± 0.075
5.293ValVal: 5.293 ± 0.082
0.747ValTrp: 0.747 ± 0.03
1.79ValTyr: 1.79 ± 0.047
0.0ValXaa: 0.0 ± 0.0
Trp
0.89TrpAla: 0.89 ± 0.032
0.148TrpCys: 0.148 ± 0.013
0.638TrpAsp: 0.638 ± 0.025
0.537TrpGlu: 0.537 ± 0.025
0.624TrpPhe: 0.624 ± 0.028
0.845TrpGly: 0.845 ± 0.034
0.457TrpHis: 0.457 ± 0.023
0.521TrpIle: 0.521 ± 0.023
0.365TrpLys: 0.365 ± 0.02
2.037TrpLeu: 2.037 ± 0.054
0.344TrpMet: 0.344 ± 0.021
0.366TrpAsn: 0.366 ± 0.021
0.565TrpPro: 0.565 ± 0.027
1.37TrpGln: 1.37 ± 0.047
0.873TrpArg: 0.873 ± 0.032
0.767TrpSer: 0.767 ± 0.026
0.467TrpThr: 0.467 ± 0.026
0.927TrpVal: 0.927 ± 0.034
0.249TrpTrp: 0.249 ± 0.018
0.411TrpTyr: 0.411 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.426TyrAla: 2.426 ± 0.056
0.373TyrCys: 0.373 ± 0.023
1.767TyrAsp: 1.767 ± 0.043
1.632TyrGlu: 1.632 ± 0.043
1.294TyrPhe: 1.294 ± 0.038
2.219TyrGly: 2.219 ± 0.049
0.893TyrHis: 0.893 ± 0.034
1.42TyrIle: 1.42 ± 0.044
1.152TyrLys: 1.152 ± 0.038
3.432TyrLeu: 3.432 ± 0.065
0.676TyrMet: 0.676 ± 0.023
1.024TyrAsn: 1.024 ± 0.036
1.45TyrPro: 1.45 ± 0.041
2.164TyrGln: 2.164 ± 0.053
2.037TyrArg: 2.037 ± 0.047
1.874TyrSer: 1.874 ± 0.046
1.356TyrThr: 1.356 ± 0.033
1.839TyrVal: 1.839 ± 0.044
0.532TyrTrp: 0.532 ± 0.026
1.089TyrTyr: 1.089 ± 0.037
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2945 proteins (972597 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski