Amino acid dipepetide frequency for Gyrovirus Tu243

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.481AlaAla: 1.481 ± 1.178
4.444AlaCys: 4.444 ± 3.055
1.481AlaAsp: 1.481 ± 2.107
2.963AlaGlu: 2.963 ± 1.796
0.0AlaPhe: 0.0 ± 0.0
5.926AlaGly: 5.926 ± 2.852
0.0AlaHis: 0.0 ± 0.0
2.963AlaIle: 2.963 ± 1.796
1.481AlaLys: 1.481 ± 1.178
1.481AlaLeu: 1.481 ± 0.898
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
0.0AlaPro: 0.0 ± 0.0
2.963AlaGln: 2.963 ± 1.801
4.444AlaArg: 4.444 ± 1.608
4.444AlaSer: 4.444 ± 1.914
7.407AlaThr: 7.407 ± 1.581
7.407AlaVal: 7.407 ± 1.581
1.481AlaTrp: 1.481 ± 0.898
2.963AlaTyr: 2.963 ± 1.796
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.481CysAsp: 1.481 ± 1.178
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.481CysGly: 1.481 ± 1.178
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
2.963CysAsn: 2.963 ± 0.69
1.481CysPro: 1.481 ± 0.898
1.481CysGln: 1.481 ± 0.898
2.963CysArg: 2.963 ± 2.345
1.481CysSer: 1.481 ± 1.178
0.0CysThr: 0.0 ± 0.0
1.481CysVal: 1.481 ± 2.107
1.481CysTrp: 1.481 ± 1.178
1.481CysTyr: 1.481 ± 2.107
0.0CysXaa: 0.0 ± 0.0
Asp
2.963AspAla: 2.963 ± 2.345
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
2.963AspGlu: 2.963 ± 1.801
0.0AspPhe: 0.0 ± 0.0
2.963AspGly: 2.963 ± 0.69
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
0.0AspLys: 0.0 ± 0.0
4.444AspLeu: 4.444 ± 1.709
1.481AspMet: 1.481 ± 1.102
1.481AspAsn: 1.481 ± 0.898
2.963AspPro: 2.963 ± 0.69
0.0AspGln: 0.0 ± 0.0
1.481AspArg: 1.481 ± 2.107
5.926AspSer: 5.926 ± 1.38
4.444AspThr: 4.444 ± 1.085
2.963AspVal: 2.963 ± 0.69
1.481AspTrp: 1.481 ± 2.107
1.481AspTyr: 1.481 ± 1.178
0.0AspXaa: 0.0 ± 0.0
Glu
4.444GluAla: 4.444 ± 3.815
0.0GluCys: 0.0 ± 0.0
2.963GluAsp: 2.963 ± 2.355
5.926GluGlu: 5.926 ± 3.992
2.963GluPhe: 2.963 ± 1.801
2.963GluGly: 2.963 ± 2.355
0.0GluHis: 0.0 ± 0.0
5.926GluIle: 5.926 ± 2.168
1.481GluLys: 1.481 ± 1.178
5.926GluLeu: 5.926 ± 3.684
2.963GluMet: 2.963 ± 0.69
0.0GluAsn: 0.0 ± 0.0
7.407GluPro: 7.407 ± 1.265
1.481GluGln: 1.481 ± 0.898
1.481GluArg: 1.481 ± 1.178
1.481GluSer: 1.481 ± 1.178
2.963GluThr: 2.963 ± 2.345
1.481GluVal: 1.481 ± 0.898
4.444GluTrp: 4.444 ± 1.085
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.481PheAla: 1.481 ± 0.898
2.963PheCys: 2.963 ± 1.796
0.0PheAsp: 0.0 ± 0.0
1.481PheGlu: 1.481 ± 1.178
1.481PhePhe: 1.481 ± 2.107
5.926PheGly: 5.926 ± 1.38
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
5.926PheLys: 5.926 ± 1.134
4.444PheLeu: 4.444 ± 1.085
2.963PheMet: 2.963 ± 0.69
1.481PheAsn: 1.481 ± 0.898
1.481PhePro: 1.481 ± 0.898
5.926PheGln: 5.926 ± 1.134
4.444PheArg: 4.444 ± 1.608
1.481PheSer: 1.481 ± 1.178
2.963PheThr: 2.963 ± 0.69
1.481PheVal: 1.481 ± 0.898
0.0PheTrp: 0.0 ± 0.0
1.481PheTyr: 1.481 ± 0.898
0.0PheXaa: 0.0 ± 0.0
Gly
5.926GlyAla: 5.926 ± 1.38
0.0GlyCys: 0.0 ± 0.0
2.963GlyAsp: 2.963 ± 1.801
5.926GlyGlu: 5.926 ± 1.134
2.963GlyPhe: 2.963 ± 2.355
22.222GlyGly: 22.222 ± 11.211
1.481GlyHis: 1.481 ± 2.107
5.926GlyIle: 5.926 ± 4.711
0.0GlyLys: 0.0 ± 0.0
7.407GlyLeu: 7.407 ± 3.055
1.481GlyMet: 1.481 ± 0.898
4.444GlyAsn: 4.444 ± 1.085
2.963GlyPro: 2.963 ± 0.69
0.0GlyGln: 0.0 ± 0.0
11.852GlyArg: 11.852 ± 2.623
4.444GlySer: 4.444 ± 1.608
10.37GlyThr: 10.37 ± 2.973
4.444GlyVal: 4.444 ± 3.055
2.963GlyTrp: 2.963 ± 1.796
1.481GlyTyr: 1.481 ± 0.898
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.481HisCys: 1.481 ± 2.107
1.481HisAsp: 1.481 ± 0.898
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
2.963HisHis: 2.963 ± 1.796
0.0HisIle: 0.0 ± 0.0
1.481HisLys: 1.481 ± 1.178
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.481HisPro: 1.481 ± 0.898
0.0HisGln: 0.0 ± 0.0
1.481HisArg: 1.481 ± 0.898
4.444HisSer: 4.444 ± 1.914
0.0HisThr: 0.0 ± 0.0
1.481HisVal: 1.481 ± 0.898
1.481HisTrp: 1.481 ± 1.178
1.481HisTyr: 1.481 ± 0.898
0.0HisXaa: 0.0 ± 0.0
Ile
2.963IleAla: 2.963 ± 2.355
0.0IleCys: 0.0 ± 0.0
1.481IleAsp: 1.481 ± 1.178
4.444IleGlu: 4.444 ± 1.085
0.0IlePhe: 0.0 ± 0.0
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
1.481IleIle: 1.481 ± 1.178
4.444IleLys: 4.444 ± 1.085
5.926IleLeu: 5.926 ± 2.168
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
1.481IlePro: 1.481 ± 1.178
0.0IleGln: 0.0 ± 0.0
1.481IleArg: 1.481 ± 0.898
5.926IleSer: 5.926 ± 2.386
1.481IleThr: 1.481 ± 1.178
1.481IleVal: 1.481 ± 0.898
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
1.481LysAsp: 1.481 ± 1.178
1.481LysGlu: 1.481 ± 2.107
4.444LysPhe: 4.444 ± 1.709
2.963LysGly: 2.963 ± 0.69
1.481LysHis: 1.481 ± 0.898
0.0LysIle: 0.0 ± 0.0
2.963LysLys: 2.963 ± 2.355
1.481LysLeu: 1.481 ± 1.178
0.0LysMet: 0.0 ± 0.0
1.481LysAsn: 1.481 ± 1.178
0.0LysPro: 0.0 ± 0.0
7.407LysGln: 7.407 ± 4.016
8.889LysArg: 8.889 ± 0.531
2.963LysSer: 2.963 ± 0.69
1.481LysThr: 1.481 ± 0.898
5.926LysVal: 5.926 ± 2.386
2.963LysTrp: 2.963 ± 0.69
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.926LeuAla: 5.926 ± 1.134
0.0LeuCys: 0.0 ± 0.0
4.444LeuAsp: 4.444 ± 1.709
11.852LeuGlu: 11.852 ± 2.442
4.444LeuPhe: 4.444 ± 2.694
2.963LeuGly: 2.963 ± 0.69
0.0LeuHis: 0.0 ± 0.0
1.481LeuIle: 1.481 ± 0.898
1.481LeuLys: 1.481 ± 1.178
7.407LeuLeu: 7.407 ± 1.581
1.481LeuMet: 1.481 ± 1.517
2.963LeuAsn: 2.963 ± 0.69
2.963LeuPro: 2.963 ± 4.213
2.963LeuGln: 2.963 ± 1.801
7.407LeuArg: 7.407 ± 1.265
7.407LeuSer: 7.407 ± 1.581
2.963LeuThr: 2.963 ± 2.355
4.444LeuVal: 4.444 ± 1.914
0.0LeuTrp: 0.0 ± 0.0
2.963LeuTyr: 2.963 ± 1.796
0.0LeuXaa: 0.0 ± 0.0
Met
1.481MetAla: 1.481 ± 0.898
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.481MetGlu: 1.481 ± 1.178
0.0MetPhe: 0.0 ± 0.0
1.481MetGly: 1.481 ± 0.898
1.481MetHis: 1.481 ± 1.178
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.963MetLeu: 2.963 ± 1.801
0.0MetMet: 0.0 ± 0.0
1.481MetAsn: 1.481 ± 0.898
0.0MetPro: 0.0 ± 0.0
1.481MetGln: 1.481 ± 0.898
1.481MetArg: 1.481 ± 0.898
1.481MetSer: 1.481 ± 1.178
1.481MetThr: 1.481 ± 0.898
2.963MetVal: 2.963 ± 1.796
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.481AsnAla: 1.481 ± 0.898
1.481AsnCys: 1.481 ± 1.178
2.963AsnAsp: 2.963 ± 1.796
0.0AsnGlu: 0.0 ± 0.0
4.444AsnPhe: 4.444 ± 1.709
1.481AsnGly: 1.481 ± 1.178
4.444AsnHis: 4.444 ± 1.085
1.481AsnIle: 1.481 ± 1.178
1.481AsnLys: 1.481 ± 0.898
0.0AsnLeu: 0.0 ± 0.0
4.444AsnMet: 4.444 ± 2.694
1.481AsnAsn: 1.481 ± 0.898
1.481AsnPro: 1.481 ± 0.898
1.481AsnGln: 1.481 ± 0.898
2.963AsnArg: 2.963 ± 1.796
1.481AsnSer: 1.481 ± 1.178
4.444AsnThr: 4.444 ± 2.694
1.481AsnVal: 1.481 ± 1.178
1.481AsnTrp: 1.481 ± 0.898
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.481ProCys: 1.481 ± 0.898
0.0ProAsp: 0.0 ± 0.0
0.0ProGlu: 0.0 ± 0.0
0.0ProPhe: 0.0 ± 0.0
7.407ProGly: 7.407 ± 3.606
1.481ProHis: 1.481 ± 0.898
1.481ProIle: 1.481 ± 2.107
4.444ProLys: 4.444 ± 1.709
5.926ProLeu: 5.926 ± 1.134
1.481ProMet: 1.481 ± 1.615
0.0ProAsn: 0.0 ± 0.0
1.481ProPro: 1.481 ± 0.898
1.481ProGln: 1.481 ± 1.178
2.963ProArg: 2.963 ± 2.355
2.963ProSer: 2.963 ± 0.69
1.481ProThr: 1.481 ± 1.178
4.444ProVal: 4.444 ± 3.055
2.963ProTrp: 2.963 ± 1.796
1.481ProTyr: 1.481 ± 0.898
0.0ProXaa: 0.0 ± 0.0
Gln
4.444GlnAla: 4.444 ± 1.608
0.0GlnCys: 0.0 ± 0.0
2.963GlnAsp: 2.963 ± 1.796
4.444GlnGlu: 4.444 ± 4.299
1.481GlnPhe: 1.481 ± 2.107
2.963GlnGly: 2.963 ± 1.796
1.481GlnHis: 1.481 ± 0.898
2.963GlnIle: 2.963 ± 1.796
2.963GlnLys: 2.963 ± 2.345
5.926GlnLeu: 5.926 ± 1.134
0.0GlnMet: 0.0 ± 0.0
1.481GlnAsn: 1.481 ± 0.898
1.481GlnPro: 1.481 ± 0.898
1.481GlnGln: 1.481 ± 0.898
1.481GlnArg: 1.481 ± 0.898
2.963GlnSer: 2.963 ± 0.69
4.444GlnThr: 4.444 ± 1.085
5.926GlnVal: 5.926 ± 2.852
2.963GlnTrp: 2.963 ± 1.796
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.481ArgAla: 1.481 ± 0.898
1.481ArgCys: 1.481 ± 1.178
1.481ArgAsp: 1.481 ± 2.107
1.481ArgGlu: 1.481 ± 1.178
4.444ArgPhe: 4.444 ± 1.709
8.889ArgGly: 8.889 ± 2.17
1.481ArgHis: 1.481 ± 2.107
2.963ArgIle: 2.963 ± 1.796
5.926ArgLys: 5.926 ± 2.168
5.926ArgLeu: 5.926 ± 1.134
0.0ArgMet: 0.0 ± 0.0
2.963ArgAsn: 2.963 ± 0.69
7.407ArgPro: 7.407 ± 1.298
1.481ArgGln: 1.481 ± 2.107
17.778ArgArg: 17.778 ± 4.121
5.926ArgSer: 5.926 ± 3.592
2.963ArgThr: 2.963 ± 1.796
4.444ArgVal: 4.444 ± 2.694
2.963ArgTrp: 2.963 ± 1.796
4.444ArgTyr: 4.444 ± 2.694
0.0ArgXaa: 0.0 ± 0.0
Ser
4.444SerAla: 4.444 ± 1.085
2.963SerCys: 2.963 ± 2.345
7.407SerAsp: 7.407 ± 3.097
7.407SerGlu: 7.407 ± 3.919
8.889SerPhe: 8.889 ± 3.599
5.926SerGly: 5.926 ± 2.852
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
1.481SerLys: 1.481 ± 1.178
5.926SerLeu: 5.926 ± 1.868
0.0SerMet: 0.0 ± 0.0
4.444SerAsn: 4.444 ± 1.085
2.963SerPro: 2.963 ± 0.69
1.481SerGln: 1.481 ± 0.898
1.481SerArg: 1.481 ± 0.898
7.407SerSer: 7.407 ± 1.265
1.481SerThr: 1.481 ± 0.898
10.37SerVal: 10.37 ± 2.634
2.963SerTrp: 2.963 ± 1.796
4.444SerTyr: 4.444 ± 1.085
0.0SerXaa: 0.0 ± 0.0
Thr
2.963ThrAla: 2.963 ± 0.69
0.0ThrCys: 0.0 ± 0.0
4.444ThrAsp: 4.444 ± 1.085
4.444ThrGlu: 4.444 ± 1.709
1.481ThrPhe: 1.481 ± 0.898
8.889ThrGly: 8.889 ± 2.069
0.0ThrHis: 0.0 ± 0.0
1.481ThrIle: 1.481 ± 1.178
1.481ThrLys: 1.481 ± 0.898
2.963ThrLeu: 2.963 ± 0.69
0.0ThrMet: 0.0 ± 0.0
5.926ThrAsn: 5.926 ± 1.868
1.481ThrPro: 1.481 ± 1.178
10.37ThrGln: 10.37 ± 2.921
0.0ThrArg: 0.0 ± 0.0
7.407ThrSer: 7.407 ± 1.265
2.963ThrThr: 2.963 ± 0.69
1.481ThrVal: 1.481 ± 0.898
1.481ThrTrp: 1.481 ± 0.898
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.926ValAla: 5.926 ± 1.38
1.481ValCys: 1.481 ± 1.178
0.0ValAsp: 0.0 ± 0.0
0.0ValGlu: 0.0 ± 0.0
2.963ValPhe: 2.963 ± 1.796
8.889ValGly: 8.889 ± 5.304
0.0ValHis: 0.0 ± 0.0
2.963ValIle: 2.963 ± 0.69
2.963ValLys: 2.963 ± 1.796
5.926ValLeu: 5.926 ± 1.38
0.0ValMet: 0.0 ± 0.0
1.481ValAsn: 1.481 ± 0.898
4.444ValPro: 4.444 ± 1.608
5.926ValGln: 5.926 ± 3.602
5.926ValArg: 5.926 ± 3.592
7.407ValSer: 7.407 ± 2.324
4.444ValThr: 4.444 ± 2.694
0.0ValVal: 0.0 ± 0.0
1.481ValTrp: 1.481 ± 2.107
4.444ValTyr: 4.444 ± 1.709
0.0ValXaa: 0.0 ± 0.0
Trp
4.444TrpAla: 4.444 ± 2.694
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
5.926TrpPhe: 5.926 ± 1.134
4.444TrpGly: 4.444 ± 2.694
1.481TrpHis: 1.481 ± 0.898
0.0TrpIle: 0.0 ± 0.0
2.963TrpLys: 2.963 ± 0.69
1.481TrpLeu: 1.481 ± 1.178
1.481TrpMet: 1.481 ± 0.898
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
2.963TrpGln: 2.963 ± 1.796
1.481TrpArg: 1.481 ± 0.898
4.444TrpSer: 4.444 ± 1.608
0.0TrpThr: 0.0 ± 0.0
1.481TrpVal: 1.481 ± 0.898
2.963TrpTrp: 2.963 ± 1.801
1.481TrpTyr: 1.481 ± 0.898
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.481TyrAla: 1.481 ± 0.898
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
1.481TyrPhe: 1.481 ± 0.898
1.481TyrGly: 1.481 ± 2.107
1.481TyrHis: 1.481 ± 0.898
1.481TyrIle: 1.481 ± 0.898
4.444TyrLys: 4.444 ± 1.085
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
5.926TyrAsn: 5.926 ± 1.868
1.481TyrPro: 1.481 ± 1.178
1.481TyrGln: 1.481 ± 1.178
4.444TyrArg: 4.444 ± 2.694
0.0TyrSer: 0.0 ± 0.0
1.481TyrThr: 1.481 ± 0.898
1.481TyrVal: 1.481 ± 0.898
1.481TyrTrp: 1.481 ± 0.898
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (676 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski