Amino acid dipepetide frequency for Black grass cryptic virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.868AlaAla: 3.868 ± 0.013
2.901AlaCys: 2.901 ± 2.06
3.868AlaAsp: 3.868 ± 0.013
2.901AlaGlu: 2.901 ± 0.7
2.901AlaPhe: 2.901 ± 0.7
4.836AlaGly: 4.836 ± 0.673
0.967AlaHis: 0.967 ± 0.694
3.868AlaIle: 3.868 ± 1.367
2.901AlaLys: 2.901 ± 0.7
3.868AlaLeu: 3.868 ± 0.013
1.934AlaMet: 1.934 ± 1.084
2.901AlaAsn: 2.901 ± 0.68
7.737AlaPro: 7.737 ± 1.354
4.836AlaGln: 4.836 ± 0.673
0.967AlaArg: 0.967 ± 0.687
3.868AlaSer: 3.868 ± 0.013
6.77AlaThr: 6.77 ± 2.047
0.967AlaVal: 0.967 ± 0.687
0.0AlaTrp: 0.0 ± 0.0
1.934AlaTyr: 1.934 ± 1.387
0.0AlaXaa: 0.0 ± 0.0
Cys
0.967CysAla: 0.967 ± 0.687
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.967CysPhe: 0.967 ± 0.694
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.967CysIle: 0.967 ± 0.694
1.934CysLys: 1.934 ± 1.387
0.0CysLeu: 0.0 ± 0.0
1.934CysMet: 1.934 ± 0.007
0.0CysAsn: 0.0 ± 0.0
1.934CysPro: 1.934 ± 1.374
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.967CysThr: 0.967 ± 0.687
0.967CysVal: 0.967 ± 0.694
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.803AspAla: 5.803 ± 2.741
0.0AspCys: 0.0 ± 0.0
3.868AspAsp: 3.868 ± 1.367
0.967AspGlu: 0.967 ± 0.694
1.934AspPhe: 1.934 ± 1.374
1.934AspGly: 1.934 ± 0.007
2.901AspHis: 2.901 ± 2.081
0.967AspIle: 0.967 ± 0.687
0.967AspLys: 0.967 ± 0.687
5.803AspLeu: 5.803 ± 2.781
1.934AspMet: 1.934 ± 0.007
2.901AspAsn: 2.901 ± 0.7
7.737AspPro: 7.737 ± 4.114
1.934AspGln: 1.934 ± 1.374
1.934AspArg: 1.934 ± 0.007
3.868AspSer: 3.868 ± 2.774
0.0AspThr: 0.0 ± 0.0
2.901AspVal: 2.901 ± 2.06
0.967AspTrp: 0.967 ± 0.694
3.868AspTyr: 3.868 ± 0.013
0.0AspXaa: 0.0 ± 0.0
Glu
1.934GluAla: 1.934 ± 1.387
0.967GluCys: 0.967 ± 0.694
1.934GluAsp: 1.934 ± 1.387
2.901GluGlu: 2.901 ± 2.06
0.967GluPhe: 0.967 ± 0.694
2.901GluGly: 2.901 ± 2.06
0.967GluHis: 0.967 ± 0.687
6.77GluIle: 6.77 ± 4.855
3.868GluLys: 3.868 ± 2.774
1.934GluLeu: 1.934 ± 1.387
0.967GluMet: 0.967 ± 0.694
3.868GluAsn: 3.868 ± 0.013
0.967GluPro: 0.967 ± 0.687
0.967GluGln: 0.967 ± 0.687
4.836GluArg: 4.836 ± 0.707
4.836GluSer: 4.836 ± 0.673
3.868GluThr: 3.868 ± 0.013
0.967GluVal: 0.967 ± 0.687
0.0GluTrp: 0.0 ± 0.0
1.934GluTyr: 1.934 ± 0.007
0.0GluXaa: 0.0 ± 0.0
Phe
4.836PheAla: 4.836 ± 2.054
0.0PheCys: 0.0 ± 0.0
4.836PheAsp: 4.836 ± 0.707
1.934PheGlu: 1.934 ± 1.387
0.967PhePhe: 0.967 ± 0.687
4.836PheGly: 4.836 ± 3.434
2.901PheHis: 2.901 ± 0.7
2.901PheIle: 2.901 ± 0.68
1.934PheLys: 1.934 ± 1.387
3.868PheLeu: 3.868 ± 0.013
1.934PheMet: 1.934 ± 0.007
4.836PheAsn: 4.836 ± 0.673
4.836PhePro: 4.836 ± 0.673
1.934PheGln: 1.934 ± 1.374
3.868PheArg: 3.868 ± 0.013
1.934PheSer: 1.934 ± 0.007
4.836PheThr: 4.836 ± 0.707
3.868PheVal: 3.868 ± 0.013
1.934PheTrp: 1.934 ± 0.007
0.967PheTyr: 0.967 ± 0.687
0.0PheXaa: 0.0 ± 0.0
Gly
1.934GlyAla: 1.934 ± 0.007
0.0GlyCys: 0.0 ± 0.0
2.901GlyAsp: 2.901 ± 0.7
1.934GlyGlu: 1.934 ± 0.007
2.901GlyPhe: 2.901 ± 0.68
0.967GlyGly: 0.967 ± 0.694
1.934GlyHis: 1.934 ± 0.007
2.901GlyIle: 2.901 ± 0.7
4.836GlyLys: 4.836 ± 0.707
3.868GlyLeu: 3.868 ± 1.367
2.901GlyMet: 2.901 ± 0.68
2.901GlyAsn: 2.901 ± 2.06
1.934GlyPro: 1.934 ± 0.007
0.0GlyGln: 0.0 ± 0.0
2.901GlyArg: 2.901 ± 2.081
1.934GlySer: 1.934 ± 1.387
1.934GlyThr: 1.934 ± 1.374
3.868GlyVal: 3.868 ± 1.394
0.967GlyTrp: 0.967 ± 0.694
2.901GlyTyr: 2.901 ± 0.7
0.0GlyXaa: 0.0 ± 0.0
His
0.967HisAla: 0.967 ± 0.687
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.967HisGlu: 0.967 ± 0.694
3.868HisPhe: 3.868 ± 1.394
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.934HisIle: 1.934 ± 0.007
0.0HisLys: 0.0 ± 0.0
0.967HisLeu: 0.967 ± 0.694
0.0HisMet: 0.0 ± 0.0
2.901HisAsn: 2.901 ± 0.7
2.901HisPro: 2.901 ± 2.06
0.967HisGln: 0.967 ± 0.687
1.934HisArg: 1.934 ± 1.387
1.934HisSer: 1.934 ± 1.374
0.967HisThr: 0.967 ± 0.694
2.901HisVal: 2.901 ± 2.06
0.0HisTrp: 0.0 ± 0.0
3.868HisTyr: 3.868 ± 2.774
0.0HisXaa: 0.0 ± 0.0
Ile
3.868IleAla: 3.868 ± 2.774
0.0IleCys: 0.0 ± 0.0
3.868IleAsp: 3.868 ± 2.747
2.901IleGlu: 2.901 ± 2.081
3.868IlePhe: 3.868 ± 1.394
2.901IleGly: 2.901 ± 2.06
2.901IleHis: 2.901 ± 0.7
5.803IleIle: 5.803 ± 0.02
2.901IleLys: 2.901 ± 2.081
3.868IleLeu: 3.868 ± 1.394
0.967IleMet: 0.967 ± 0.694
3.868IleAsn: 3.868 ± 2.774
12.573IlePro: 12.573 ± 7.548
3.868IleGln: 3.868 ± 1.394
0.0IleArg: 0.0 ± 0.0
2.901IleSer: 2.901 ± 0.68
3.868IleThr: 3.868 ± 0.013
3.868IleVal: 3.868 ± 0.013
0.0IleTrp: 0.0 ± 0.0
0.967IleTyr: 0.967 ± 0.694
0.0IleXaa: 0.0 ± 0.0
Lys
1.934LysAla: 1.934 ± 1.387
1.934LysCys: 1.934 ± 1.387
1.934LysAsp: 1.934 ± 0.007
0.967LysGlu: 0.967 ± 0.687
3.868LysPhe: 3.868 ± 1.394
0.0LysGly: 0.0 ± 0.0
3.868LysHis: 3.868 ± 0.013
1.934LysIle: 1.934 ± 1.387
2.901LysLys: 2.901 ± 0.68
3.868LysLeu: 3.868 ± 2.774
0.967LysMet: 0.967 ± 0.694
1.934LysAsn: 1.934 ± 1.387
3.868LysPro: 3.868 ± 1.367
2.901LysGln: 2.901 ± 0.68
0.967LysArg: 0.967 ± 0.687
4.836LysSer: 4.836 ± 0.673
2.901LysThr: 2.901 ± 0.7
4.836LysVal: 4.836 ± 2.087
1.934LysTrp: 1.934 ± 1.387
4.836LysTyr: 4.836 ± 0.707
0.0LysXaa: 0.0 ± 0.0
Leu
5.803LeuAla: 5.803 ± 1.36
0.0LeuCys: 0.0 ± 0.0
4.836LeuAsp: 4.836 ± 0.707
5.803LeuGlu: 5.803 ± 0.02
4.836LeuPhe: 4.836 ± 2.087
6.77LeuGly: 6.77 ± 3.474
0.0LeuHis: 0.0 ± 0.0
3.868LeuIle: 3.868 ± 0.013
3.868LeuLys: 3.868 ± 1.394
9.671LeuLeu: 9.671 ± 4.174
2.901LeuMet: 2.901 ± 0.7
0.967LeuAsn: 0.967 ± 0.687
2.901LeuPro: 2.901 ± 2.06
1.934LeuGln: 1.934 ± 1.374
4.836LeuArg: 4.836 ± 0.673
5.803LeuSer: 5.803 ± 2.781
4.836LeuThr: 4.836 ± 0.707
5.803LeuVal: 5.803 ± 1.36
0.967LeuTrp: 0.967 ± 0.694
5.803LeuTyr: 5.803 ± 2.781
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.967MetCys: 0.967 ± 0.687
1.934MetAsp: 1.934 ± 1.374
1.934MetGlu: 1.934 ± 0.007
3.868MetPhe: 3.868 ± 0.013
0.967MetGly: 0.967 ± 0.694
0.967MetHis: 0.967 ± 0.687
0.967MetIle: 0.967 ± 0.694
0.967MetLys: 0.967 ± 0.694
1.934MetLeu: 1.934 ± 0.007
1.934MetMet: 1.934 ± 1.374
3.868MetAsn: 3.868 ± 1.367
0.967MetPro: 0.967 ± 0.694
0.0MetGln: 0.0 ± 0.0
1.934MetArg: 1.934 ± 0.007
1.934MetSer: 1.934 ± 0.007
1.934MetThr: 1.934 ± 0.007
0.967MetVal: 0.967 ± 0.694
0.0MetTrp: 0.0 ± 0.0
0.967MetTyr: 0.967 ± 0.694
0.0MetXaa: 0.0 ± 0.0
Asn
5.803AsnAla: 5.803 ± 0.02
0.967AsnCys: 0.967 ± 0.694
2.901AsnAsp: 2.901 ± 0.68
3.868AsnGlu: 3.868 ± 0.013
2.901AsnPhe: 2.901 ± 0.68
6.77AsnGly: 6.77 ± 3.474
0.0AsnHis: 0.0 ± 0.0
5.803AsnIle: 5.803 ± 2.741
3.868AsnLys: 3.868 ± 1.367
3.868AsnLeu: 3.868 ± 1.367
0.967AsnMet: 0.967 ± 0.687
5.803AsnAsn: 5.803 ± 4.121
0.967AsnPro: 0.967 ± 0.687
0.967AsnGln: 0.967 ± 0.694
4.836AsnArg: 4.836 ± 0.707
1.934AsnSer: 1.934 ± 0.007
2.901AsnThr: 2.901 ± 0.7
0.967AsnVal: 0.967 ± 0.687
0.967AsnTrp: 0.967 ± 0.687
1.934AsnTyr: 1.934 ± 0.007
0.0AsnXaa: 0.0 ± 0.0
Pro
2.901ProAla: 2.901 ± 2.06
0.0ProCys: 0.0 ± 0.0
8.704ProAsp: 8.704 ± 2.04
5.803ProGlu: 5.803 ± 1.36
4.836ProPhe: 4.836 ± 0.673
3.868ProGly: 3.868 ± 0.013
1.934ProHis: 1.934 ± 0.007
2.901ProIle: 2.901 ± 0.68
3.868ProLys: 3.868 ± 1.367
7.737ProLeu: 7.737 ± 0.027
0.967ProMet: 0.967 ± 0.48
4.836ProAsn: 4.836 ± 3.434
5.803ProPro: 5.803 ± 1.36
2.901ProGln: 2.901 ± 0.7
2.901ProArg: 2.901 ± 0.68
4.836ProSer: 4.836 ± 0.673
7.737ProThr: 7.737 ± 2.734
3.868ProVal: 3.868 ± 1.367
0.967ProTrp: 0.967 ± 0.694
0.967ProTyr: 0.967 ± 0.694
0.0ProXaa: 0.0 ± 0.0
Gln
1.934GlnAla: 1.934 ± 0.007
0.0GlnCys: 0.0 ± 0.0
2.901GlnAsp: 2.901 ± 0.68
0.0GlnGlu: 0.0 ± 0.0
1.934GlnPhe: 1.934 ± 1.374
0.967GlnGly: 0.967 ± 0.687
0.0GlnHis: 0.0 ± 0.0
2.901GlnIle: 2.901 ± 2.081
2.901GlnLys: 2.901 ± 0.7
6.77GlnLeu: 6.77 ± 3.427
0.0GlnMet: 0.0 ± 0.0
1.934GlnAsn: 1.934 ± 1.374
1.934GlnPro: 1.934 ± 1.387
0.967GlnGln: 0.967 ± 0.687
1.934GlnArg: 1.934 ± 1.374
0.967GlnSer: 0.967 ± 0.687
1.934GlnThr: 1.934 ± 1.374
2.901GlnVal: 2.901 ± 2.06
1.934GlnTrp: 1.934 ± 0.007
0.967GlnTyr: 0.967 ± 0.694
0.0GlnXaa: 0.0 ± 0.0
Arg
1.934ArgAla: 1.934 ± 1.374
0.967ArgCys: 0.967 ± 0.694
1.934ArgAsp: 1.934 ± 0.007
0.0ArgGlu: 0.0 ± 0.0
4.836ArgPhe: 4.836 ± 2.054
0.967ArgGly: 0.967 ± 0.687
0.967ArgHis: 0.967 ± 0.687
2.901ArgIle: 2.901 ± 0.7
0.967ArgLys: 0.967 ± 0.694
5.803ArgLeu: 5.803 ± 0.02
1.934ArgMet: 1.934 ± 1.387
4.836ArgAsn: 4.836 ± 2.087
4.836ArgPro: 4.836 ± 0.707
0.967ArgGln: 0.967 ± 0.694
1.934ArgArg: 1.934 ± 0.007
3.868ArgSer: 3.868 ± 1.367
4.836ArgThr: 4.836 ± 3.468
4.836ArgVal: 4.836 ± 0.707
0.0ArgTrp: 0.0 ± 0.0
0.967ArgTyr: 0.967 ± 0.694
0.0ArgXaa: 0.0 ± 0.0
Ser
6.77SerAla: 6.77 ± 2.047
0.0SerCys: 0.0 ± 0.0
1.934SerAsp: 1.934 ± 0.007
3.868SerGlu: 3.868 ± 0.013
3.868SerPhe: 3.868 ± 0.013
2.901SerGly: 2.901 ± 0.7
0.0SerHis: 0.0 ± 0.0
2.901SerIle: 2.901 ± 0.68
4.836SerLys: 4.836 ± 0.707
6.77SerLeu: 6.77 ± 2.094
0.0SerMet: 0.0 ± 0.0
3.868SerAsn: 3.868 ± 0.013
1.934SerPro: 1.934 ± 0.007
2.901SerGln: 2.901 ± 2.06
3.868SerArg: 3.868 ± 1.394
7.737SerSer: 7.737 ± 1.407
5.803SerThr: 5.803 ± 1.36
1.934SerVal: 1.934 ± 0.007
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.77ThrAla: 6.77 ± 0.667
0.0ThrCys: 0.0 ± 0.0
1.934ThrAsp: 1.934 ± 0.007
4.836ThrGlu: 4.836 ± 2.087
3.868ThrPhe: 3.868 ± 1.367
1.934ThrGly: 1.934 ± 1.387
3.868ThrHis: 3.868 ± 2.747
6.77ThrIle: 6.77 ± 0.714
4.836ThrLys: 4.836 ± 2.087
2.901ThrLeu: 2.901 ± 0.7
3.868ThrMet: 3.868 ± 1.367
1.934ThrAsn: 1.934 ± 0.007
5.803ThrPro: 5.803 ± 1.36
3.868ThrGln: 3.868 ± 1.367
3.868ThrArg: 3.868 ± 0.013
1.934ThrSer: 1.934 ± 1.374
3.868ThrThr: 3.868 ± 0.013
1.934ThrVal: 1.934 ± 0.007
0.967ThrTrp: 0.967 ± 0.687
0.967ThrTyr: 0.967 ± 0.694
0.0ThrXaa: 0.0 ± 0.0
Val
2.901ValAla: 2.901 ± 2.06
1.934ValCys: 1.934 ± 0.007
0.0ValAsp: 0.0 ± 0.0
3.868ValGlu: 3.868 ± 1.394
4.836ValPhe: 4.836 ± 3.434
0.967ValGly: 0.967 ± 0.694
1.934ValHis: 1.934 ± 1.387
5.803ValIle: 5.803 ± 0.02
2.901ValLys: 2.901 ± 0.68
4.836ValLeu: 4.836 ± 0.673
0.967ValMet: 0.967 ± 0.687
1.934ValAsn: 1.934 ± 1.374
3.868ValPro: 3.868 ± 1.394
2.901ValGln: 2.901 ± 0.68
2.901ValArg: 2.901 ± 0.7
3.868ValSer: 3.868 ± 1.367
2.901ValThr: 2.901 ± 0.68
0.967ValVal: 0.967 ± 0.687
2.901ValTrp: 2.901 ± 0.7
0.967ValTyr: 0.967 ± 0.694
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.967TrpPhe: 0.967 ± 0.687
0.967TrpGly: 0.967 ± 0.694
0.0TrpHis: 0.0 ± 0.0
0.967TrpIle: 0.967 ± 0.687
1.934TrpLys: 1.934 ± 0.007
0.967TrpLeu: 0.967 ± 0.694
0.967TrpMet: 0.967 ± 0.694
0.0TrpAsn: 0.0 ± 0.0
2.901TrpPro: 2.901 ± 2.081
0.967TrpGln: 0.967 ± 0.687
0.0TrpArg: 0.0 ± 0.0
1.934TrpSer: 1.934 ± 1.387
2.901TrpThr: 2.901 ± 0.7
0.967TrpVal: 0.967 ± 0.687
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.868TyrAla: 3.868 ± 2.774
0.0TyrCys: 0.0 ± 0.0
2.901TyrAsp: 2.901 ± 0.7
2.901TyrGlu: 2.901 ± 2.081
0.967TyrPhe: 0.967 ± 0.687
0.967TyrGly: 0.967 ± 0.694
0.967TyrHis: 0.967 ± 0.694
1.934TyrIle: 1.934 ± 1.374
0.0TyrLys: 0.0 ± 0.0
2.901TyrLeu: 2.901 ± 2.081
0.0TyrMet: 0.0 ± 0.0
2.901TyrAsn: 2.901 ± 0.7
2.901TyrPro: 2.901 ± 2.081
0.0TyrGln: 0.0 ± 0.0
3.868TyrArg: 3.868 ± 2.774
0.967TyrSer: 0.967 ± 0.687
0.967TyrThr: 0.967 ± 0.687
3.868TyrVal: 3.868 ± 1.394
1.934TyrTrp: 1.934 ± 0.007
1.934TyrTyr: 1.934 ± 0.007
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1035 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski