Amino acid dipepetide frequency for Leptonychotes weddellii papillomavirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.412AlaAla: 5.412 ± 3.068
2.082AlaCys: 2.082 ± 1.406
4.58AlaAsp: 4.58 ± 1.173
4.996AlaGlu: 4.996 ± 1.775
4.58AlaPhe: 4.58 ± 0.775
4.58AlaGly: 4.58 ± 1.002
0.416AlaHis: 0.416 ± 0.358
1.665AlaIle: 1.665 ± 0.596
3.747AlaLys: 3.747 ± 0.811
5.828AlaLeu: 5.828 ± 1.939
0.833AlaMet: 0.833 ± 0.865
2.082AlaAsn: 2.082 ± 1.1
5.412AlaPro: 5.412 ± 1.892
1.665AlaGln: 1.665 ± 0.606
4.163AlaArg: 4.163 ± 1.607
6.661AlaSer: 6.661 ± 0.792
4.58AlaThr: 4.58 ± 1.644
3.331AlaVal: 3.331 ± 1.512
0.416AlaTrp: 0.416 ± 0.335
1.249AlaTyr: 1.249 ± 0.611
0.0AlaXaa: 0.0 ± 0.0
Cys
2.498CysAla: 2.498 ± 0.771
0.416CysCys: 0.416 ± 0.579
0.833CysAsp: 0.833 ± 0.718
2.498CysGlu: 2.498 ± 1.474
2.082CysPhe: 2.082 ± 1.007
0.833CysGly: 0.833 ± 0.615
0.833CysHis: 0.833 ± 0.558
0.833CysIle: 0.833 ± 0.566
2.082CysLys: 2.082 ± 0.744
2.498CysLeu: 2.498 ± 1.519
0.416CysMet: 0.416 ± 0.335
1.249CysAsn: 1.249 ± 0.682
2.914CysPro: 2.914 ± 1.16
0.833CysGln: 0.833 ± 0.566
1.665CysArg: 1.665 ± 0.836
0.416CysSer: 0.416 ± 0.335
0.833CysThr: 0.833 ± 0.45
1.249CysVal: 1.249 ± 0.8
0.833CysTrp: 0.833 ± 0.469
0.416CysTyr: 0.416 ± 0.335
0.0CysXaa: 0.0 ± 0.0
Asp
6.661AspAla: 6.661 ± 0.903
1.249AspCys: 1.249 ± 1.006
4.163AspAsp: 4.163 ± 1.226
3.331AspGlu: 3.331 ± 1.009
2.082AspPhe: 2.082 ± 0.337
3.747AspGly: 3.747 ± 1.259
0.833AspHis: 0.833 ± 0.409
2.914AspIle: 2.914 ± 1.206
0.416AspLys: 0.416 ± 0.432
4.163AspLeu: 4.163 ± 1.891
1.249AspMet: 1.249 ± 0.405
1.665AspAsn: 1.665 ± 0.606
4.996AspPro: 4.996 ± 1.231
1.665AspGln: 1.665 ± 0.566
1.665AspArg: 1.665 ± 1.039
4.996AspSer: 4.996 ± 1.142
6.245AspThr: 6.245 ± 2.334
4.58AspVal: 4.58 ± 1.229
2.498AspTrp: 2.498 ± 0.894
2.082AspTyr: 2.082 ± 0.876
0.0AspXaa: 0.0 ± 0.0
Glu
4.58GluAla: 4.58 ± 1.263
1.249GluCys: 1.249 ± 0.609
6.245GluAsp: 6.245 ± 1.472
5.412GluGlu: 5.412 ± 1.384
2.082GluPhe: 2.082 ± 0.892
5.412GluGly: 5.412 ± 1.52
1.249GluHis: 1.249 ± 0.71
1.665GluIle: 1.665 ± 0.707
2.082GluLys: 2.082 ± 1.119
4.996GluLeu: 4.996 ± 0.47
0.833GluMet: 0.833 ± 0.45
1.249GluAsn: 1.249 ± 0.829
3.747GluPro: 3.747 ± 1.531
3.747GluGln: 3.747 ± 1.097
2.914GluArg: 2.914 ± 1.734
3.331GluSer: 3.331 ± 1.562
4.996GluThr: 4.996 ± 1.328
5.828GluVal: 5.828 ± 2.265
0.416GluTrp: 0.416 ± 0.335
2.082GluTyr: 2.082 ± 0.626
0.0GluXaa: 0.0 ± 0.0
Phe
2.082PheAla: 2.082 ± 0.59
0.833PheCys: 0.833 ± 0.566
1.665PheAsp: 1.665 ± 0.932
1.665PheGlu: 1.665 ± 1.431
2.498PhePhe: 2.498 ± 0.609
2.498PheGly: 2.498 ± 0.75
0.416PheHis: 0.416 ± 0.358
1.665PheIle: 1.665 ± 1.183
2.498PheLys: 2.498 ± 1.295
4.58PheLeu: 4.58 ± 1.171
0.416PheMet: 0.416 ± 0.354
3.331PheAsn: 3.331 ± 2.387
2.498PhePro: 2.498 ± 0.886
0.833PheGln: 0.833 ± 0.671
2.082PheArg: 2.082 ± 0.337
2.498PheSer: 2.498 ± 0.921
0.833PheThr: 0.833 ± 0.566
2.498PheVal: 2.498 ± 0.828
2.082PheTrp: 2.082 ± 0.739
0.833PheTyr: 0.833 ± 0.409
0.0PheXaa: 0.0 ± 0.0
Gly
2.914GlyAla: 2.914 ± 1.2
0.833GlyCys: 0.833 ± 0.469
4.58GlyAsp: 4.58 ± 1.499
6.661GlyGlu: 6.661 ± 1.416
0.416GlyPhe: 0.416 ± 0.335
7.91GlyGly: 7.91 ± 3.624
2.914GlyHis: 2.914 ± 1.326
1.249GlyIle: 1.249 ± 0.863
2.082GlyLys: 2.082 ± 0.66
4.163GlyLeu: 4.163 ± 0.928
0.416GlyMet: 0.416 ± 0.358
2.914GlyAsn: 2.914 ± 0.503
5.828GlyPro: 5.828 ± 2.419
2.914GlyGln: 2.914 ± 1.169
7.077GlyArg: 7.077 ± 1.163
6.661GlySer: 6.661 ± 1.61
6.661GlyThr: 6.661 ± 2.128
6.661GlyVal: 6.661 ± 0.834
0.416GlyTrp: 0.416 ± 0.354
4.163GlyTyr: 4.163 ± 0.782
0.0GlyXaa: 0.0 ± 0.0
His
1.665HisAla: 1.665 ± 0.612
1.665HisCys: 1.665 ± 0.76
1.665HisAsp: 1.665 ± 0.641
0.0HisGlu: 0.0 ± 0.0
1.665HisPhe: 1.665 ± 0.504
1.665HisGly: 1.665 ± 0.528
0.0HisHis: 0.0 ± 0.0
0.416HisIle: 0.416 ± 0.358
2.082HisLys: 2.082 ± 1.107
0.416HisLeu: 0.416 ± 0.432
0.0HisMet: 0.0 ± 0.0
0.833HisAsn: 0.833 ± 0.397
2.082HisPro: 2.082 ± 1.017
1.249HisGln: 1.249 ± 0.609
1.665HisArg: 1.665 ± 0.868
0.833HisSer: 0.833 ± 0.397
0.416HisThr: 0.416 ± 0.354
1.665HisVal: 1.665 ± 0.606
0.833HisTrp: 0.833 ± 0.469
0.833HisTyr: 0.833 ± 0.397
0.0HisXaa: 0.0 ± 0.0
Ile
1.249IleAla: 1.249 ± 0.374
0.833IleCys: 0.833 ± 0.865
1.249IleAsp: 1.249 ± 0.616
2.914IleGlu: 2.914 ± 0.903
0.833IlePhe: 0.833 ± 0.592
2.914IleGly: 2.914 ± 1.631
1.249IleHis: 1.249 ± 0.737
0.416IleIle: 0.416 ± 0.358
0.833IleLys: 0.833 ± 0.409
2.082IleLeu: 2.082 ± 1.018
0.0IleMet: 0.0 ± 0.0
0.833IleAsn: 0.833 ± 0.5
0.416IlePro: 0.416 ± 0.354
0.833IleGln: 0.833 ± 0.671
2.082IleArg: 2.082 ± 1.723
4.58IleSer: 4.58 ± 3.27
1.249IleThr: 1.249 ± 0.668
1.665IleVal: 1.665 ± 0.868
0.0IleTrp: 0.0 ± 0.0
0.833IleTyr: 0.833 ± 0.409
0.0IleXaa: 0.0 ± 0.0
Lys
3.747LysAla: 3.747 ± 1.215
1.249LysCys: 1.249 ± 0.71
0.833LysAsp: 0.833 ± 0.409
0.833LysGlu: 0.833 ± 0.615
2.082LysPhe: 2.082 ± 0.984
2.082LysGly: 2.082 ± 0.692
1.249LysHis: 1.249 ± 0.71
0.416LysIle: 0.416 ± 0.475
3.331LysLys: 3.331 ± 1.115
1.665LysLeu: 1.665 ± 0.707
1.249LysMet: 1.249 ± 0.738
1.249LysAsn: 1.249 ± 0.559
2.498LysPro: 2.498 ± 0.833
1.249LysGln: 1.249 ± 0.71
5.412LysArg: 5.412 ± 0.844
2.914LysSer: 2.914 ± 0.94
2.082LysThr: 2.082 ± 0.739
4.163LysVal: 4.163 ± 1.131
0.833LysTrp: 0.833 ± 0.397
2.082LysTyr: 2.082 ± 0.81
0.0LysXaa: 0.0 ± 0.0
Leu
4.58LeuAla: 4.58 ± 1.405
2.498LeuCys: 2.498 ± 1.248
6.245LeuAsp: 6.245 ± 1.901
4.996LeuGlu: 4.996 ± 2.42
4.58LeuPhe: 4.58 ± 1.559
7.494LeuGly: 7.494 ± 2.054
2.914LeuHis: 2.914 ± 1.444
1.249LeuIle: 1.249 ± 0.379
3.331LeuLys: 3.331 ± 1.156
8.326LeuLeu: 8.326 ± 1.931
1.665LeuMet: 1.665 ± 0.383
1.665LeuAsn: 1.665 ± 0.899
3.331LeuPro: 3.331 ± 1.469
2.498LeuGln: 2.498 ± 0.813
5.828LeuArg: 5.828 ± 0.959
5.828LeuSer: 5.828 ± 0.979
5.828LeuThr: 5.828 ± 0.716
6.661LeuVal: 6.661 ± 1.4
0.833LeuTrp: 0.833 ± 0.566
2.914LeuTyr: 2.914 ± 0.503
0.0LeuXaa: 0.0 ± 0.0
Met
2.082MetAla: 2.082 ± 1.208
0.0MetCys: 0.0 ± 0.0
1.249MetAsp: 1.249 ± 0.772
1.665MetGlu: 1.665 ± 1.112
0.0MetPhe: 0.0 ± 0.0
0.416MetGly: 0.416 ± 0.432
0.833MetHis: 0.833 ± 0.387
1.249MetIle: 1.249 ± 0.637
0.0MetLys: 0.0 ± 0.0
0.416MetLeu: 0.416 ± 0.354
0.0MetMet: 0.0 ± 0.0
0.416MetAsn: 0.416 ± 0.432
0.416MetPro: 0.416 ± 0.432
0.416MetGln: 0.416 ± 0.335
2.082MetArg: 2.082 ± 0.984
1.249MetSer: 1.249 ± 0.63
0.0MetThr: 0.0 ± 0.0
0.833MetVal: 0.833 ± 0.671
0.416MetTrp: 0.416 ± 0.354
0.416MetTyr: 0.416 ± 0.432
0.0MetXaa: 0.0 ± 0.0
Asn
0.833AsnAla: 0.833 ± 0.671
0.416AsnCys: 0.416 ± 0.335
1.665AsnAsp: 1.665 ± 0.528
1.665AsnGlu: 1.665 ± 1.039
0.416AsnPhe: 0.416 ± 0.432
0.833AsnGly: 0.833 ± 0.865
0.416AsnHis: 0.416 ± 0.579
1.665AsnIle: 1.665 ± 0.952
1.665AsnLys: 1.665 ± 1.271
1.665AsnLeu: 1.665 ± 0.768
0.833AsnMet: 0.833 ± 0.528
1.249AsnAsn: 1.249 ± 0.611
3.331AsnPro: 3.331 ± 1.383
2.498AsnGln: 2.498 ± 0.616
2.914AsnArg: 2.914 ± 1.438
3.331AsnSer: 3.331 ± 0.486
1.249AsnThr: 1.249 ± 0.374
2.498AsnVal: 2.498 ± 0.609
0.833AsnTrp: 0.833 ± 0.671
0.416AsnTyr: 0.416 ± 0.432
0.0AsnXaa: 0.0 ± 0.0
Pro
5.828ProAla: 5.828 ± 2.119
2.082ProCys: 2.082 ± 0.697
5.828ProAsp: 5.828 ± 2.281
3.747ProGlu: 3.747 ± 0.749
1.665ProPhe: 1.665 ± 0.606
6.245ProGly: 6.245 ± 2.707
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
2.498ProLys: 2.498 ± 0.811
6.245ProLeu: 6.245 ± 1.65
0.416ProMet: 0.416 ± 0.335
1.665ProAsn: 1.665 ± 0.606
7.91ProPro: 7.91 ± 2.515
0.416ProGln: 0.416 ± 0.354
4.996ProArg: 4.996 ± 1.142
6.245ProSer: 6.245 ± 1.702
4.996ProThr: 4.996 ± 0.793
7.077ProVal: 7.077 ± 1.045
0.416ProTrp: 0.416 ± 0.354
1.665ProTyr: 1.665 ± 1.049
0.0ProXaa: 0.0 ± 0.0
Gln
2.914GlnAla: 2.914 ± 1.154
0.0GlnCys: 0.0 ± 0.0
0.833GlnAsp: 0.833 ± 0.469
3.747GlnGlu: 3.747 ± 1.729
0.0GlnPhe: 0.0 ± 0.0
3.331GlnGly: 3.331 ± 0.7
0.416GlnHis: 0.416 ± 0.335
0.833GlnIle: 0.833 ± 0.45
0.833GlnLys: 0.833 ± 0.865
4.996GlnLeu: 4.996 ± 1.022
0.416GlnMet: 0.416 ± 0.432
2.082GlnAsn: 2.082 ± 0.901
2.082GlnPro: 2.082 ± 0.81
1.665GlnGln: 1.665 ± 1.015
0.833GlnArg: 0.833 ± 0.397
0.833GlnSer: 0.833 ± 0.409
2.914GlnThr: 2.914 ± 0.899
2.914GlnVal: 2.914 ± 0.922
0.416GlnTrp: 0.416 ± 0.335
0.416GlnTyr: 0.416 ± 0.432
0.0GlnXaa: 0.0 ± 0.0
Arg
6.661ArgAla: 6.661 ± 1.002
3.331ArgCys: 3.331 ± 1.513
2.082ArgAsp: 2.082 ± 1.643
2.498ArgGlu: 2.498 ± 1.353
1.249ArgPhe: 1.249 ± 0.616
5.412ArgGly: 5.412 ± 0.936
2.082ArgHis: 2.082 ± 0.95
1.665ArgIle: 1.665 ± 0.963
2.498ArgLys: 2.498 ± 0.402
7.91ArgLeu: 7.91 ± 1.181
1.249ArgMet: 1.249 ± 0.611
0.833ArgAsn: 0.833 ± 0.409
4.996ArgPro: 4.996 ± 1.674
2.082ArgGln: 2.082 ± 0.346
7.077ArgArg: 7.077 ± 1.841
4.996ArgSer: 4.996 ± 1.64
4.58ArgThr: 4.58 ± 1.25
3.331ArgVal: 3.331 ± 1.107
1.249ArgTrp: 1.249 ± 0.8
2.914ArgTyr: 2.914 ± 0.531
0.0ArgXaa: 0.0 ± 0.0
Ser
3.331SerAla: 3.331 ± 0.995
1.249SerCys: 1.249 ± 0.921
4.58SerAsp: 4.58 ± 1.022
5.412SerGlu: 5.412 ± 1.306
2.914SerPhe: 2.914 ± 1.056
8.326SerGly: 8.326 ± 2.019
2.498SerHis: 2.498 ± 1.205
2.914SerIle: 2.914 ± 0.656
4.163SerLys: 4.163 ± 0.991
7.077SerLeu: 7.077 ± 1.729
1.249SerMet: 1.249 ± 0.625
1.249SerAsn: 1.249 ± 0.63
5.412SerPro: 5.412 ± 2.502
2.498SerGln: 2.498 ± 0.486
4.58SerArg: 4.58 ± 1.125
11.241SerSer: 11.241 ± 3.063
6.661SerThr: 6.661 ± 1.348
5.412SerVal: 5.412 ± 1.871
0.0SerTrp: 0.0 ± 0.0
1.249SerTyr: 1.249 ± 0.63
0.0SerXaa: 0.0 ± 0.0
Thr
3.331ThrAla: 3.331 ± 0.999
2.082ThrCys: 2.082 ± 0.754
4.996ThrAsp: 4.996 ± 0.606
2.914ThrGlu: 2.914 ± 1.323
4.58ThrPhe: 4.58 ± 1.459
5.828ThrGly: 5.828 ± 1.81
0.0ThrHis: 0.0 ± 0.0
1.249ThrIle: 1.249 ± 0.666
2.498ThrLys: 2.498 ± 0.811
4.58ThrLeu: 4.58 ± 0.749
0.833ThrMet: 0.833 ± 0.409
2.082ThrAsn: 2.082 ± 0.744
5.412ThrPro: 5.412 ± 0.813
1.665ThrGln: 1.665 ± 0.642
3.747ThrArg: 3.747 ± 1.027
6.245ThrSer: 6.245 ± 1.36
4.996ThrThr: 4.996 ± 1.387
6.661ThrVal: 6.661 ± 0.731
0.0ThrTrp: 0.0 ± 0.0
4.996ThrTyr: 4.996 ± 1.869
0.0ThrXaa: 0.0 ± 0.0
Val
3.747ValAla: 3.747 ± 1.343
2.498ValCys: 2.498 ± 1.037
6.245ValAsp: 6.245 ± 2.646
4.996ValGlu: 4.996 ± 0.966
2.498ValPhe: 2.498 ± 0.941
3.331ValGly: 3.331 ± 0.91
2.498ValHis: 2.498 ± 1.638
4.163ValIle: 4.163 ± 1.558
2.082ValLys: 2.082 ± 1.029
7.077ValLeu: 7.077 ± 1.996
0.416ValMet: 0.416 ± 0.335
2.498ValAsn: 2.498 ± 0.418
4.163ValPro: 4.163 ± 1.532
1.665ValGln: 1.665 ± 0.896
5.412ValArg: 5.412 ± 2.392
7.077ValSer: 7.077 ± 0.939
5.828ValThr: 5.828 ± 0.752
4.996ValVal: 4.996 ± 1.356
1.665ValTrp: 1.665 ± 0.767
2.498ValTyr: 2.498 ± 0.813
0.0ValXaa: 0.0 ± 0.0
Trp
1.665TrpAla: 1.665 ± 0.709
0.833TrpCys: 0.833 ± 0.558
0.0TrpAsp: 0.0 ± 0.0
0.833TrpGlu: 0.833 ± 0.592
0.416TrpPhe: 0.416 ± 0.335
1.249TrpGly: 1.249 ± 0.737
0.416TrpHis: 0.416 ± 0.354
0.416TrpIle: 0.416 ± 0.335
1.249TrpLys: 1.249 ± 0.8
1.665TrpLeu: 1.665 ± 0.896
0.0TrpMet: 0.0 ± 0.0
0.416TrpAsn: 0.416 ± 0.432
0.416TrpPro: 0.416 ± 0.354
0.833TrpGln: 0.833 ± 0.709
0.833TrpArg: 0.833 ± 0.566
0.416TrpSer: 0.416 ± 0.335
1.249TrpThr: 1.249 ± 0.71
1.249TrpVal: 1.249 ± 0.737
0.416TrpTrp: 0.416 ± 0.354
0.416TrpTyr: 0.416 ± 0.335
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.498TyrAla: 2.498 ± 0.801
0.833TyrCys: 0.833 ± 1.157
1.665TyrAsp: 1.665 ± 0.709
3.331TyrGlu: 3.331 ± 0.442
1.665TyrPhe: 1.665 ± 0.606
3.331TyrGly: 3.331 ± 1.112
0.416TyrHis: 0.416 ± 0.432
0.416TyrIle: 0.416 ± 0.432
1.249TyrLys: 1.249 ± 0.611
3.331TyrLeu: 3.331 ± 1.167
1.249TyrMet: 1.249 ± 0.611
0.833TyrAsn: 0.833 ± 0.598
2.082TyrPro: 2.082 ± 0.68
1.249TyrGln: 1.249 ± 0.737
1.665TyrArg: 1.665 ± 0.768
1.665TyrSer: 1.665 ± 0.584
2.498TyrThr: 2.498 ± 0.978
2.082TyrVal: 2.082 ± 0.416
0.416TyrTrp: 0.416 ± 0.432
2.082TyrTyr: 2.082 ± 0.81
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2403 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski