Amino acid dipepetide frequency for Tortoise microvirus 43

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.91AlaAla: 5.91 ± 1.125
0.591AlaCys: 0.591 ± 0.559
1.182AlaAsp: 1.182 ± 0.57
10.047AlaGlu: 10.047 ± 1.393
3.546AlaPhe: 3.546 ± 1.435
5.91AlaGly: 5.91 ± 1.855
1.773AlaHis: 1.773 ± 1.877
2.955AlaIle: 2.955 ± 0.817
8.865AlaLys: 8.865 ± 3.232
2.955AlaLeu: 2.955 ± 1.004
1.773AlaMet: 1.773 ± 1.2
4.728AlaAsn: 4.728 ± 1.931
7.683AlaPro: 7.683 ± 1.864
1.182AlaGln: 1.182 ± 0.612
9.456AlaArg: 9.456 ± 2.312
4.137AlaSer: 4.137 ± 2.099
7.092AlaThr: 7.092 ± 2.324
9.456AlaVal: 9.456 ± 4.721
1.182AlaTrp: 1.182 ± 0.71
3.546AlaTyr: 3.546 ± 1.42
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.182CysGly: 1.182 ± 1.114
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.773CysLys: 1.773 ± 1.152
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.182CysVal: 1.182 ± 1.251
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.546AspAla: 3.546 ± 0.975
0.591AspCys: 0.591 ± 0.626
1.182AspAsp: 1.182 ± 0.544
2.955AspGlu: 2.955 ± 1.55
2.364AspPhe: 2.364 ± 0.753
7.092AspGly: 7.092 ± 2.061
2.364AspHis: 2.364 ± 0.735
1.182AspIle: 1.182 ± 0.749
1.773AspLys: 1.773 ± 0.796
3.546AspLeu: 3.546 ± 1.126
0.591AspMet: 0.591 ± 0.397
2.955AspAsn: 2.955 ± 1.476
3.546AspPro: 3.546 ± 1.345
2.955AspGln: 2.955 ± 1.02
3.546AspArg: 3.546 ± 1.344
3.546AspSer: 3.546 ± 1.047
1.182AspThr: 1.182 ± 0.793
1.182AspVal: 1.182 ± 0.544
3.546AspTrp: 3.546 ± 1.134
1.182AspTyr: 1.182 ± 0.878
0.0AspXaa: 0.0 ± 0.0
Glu
5.319GluAla: 5.319 ± 1.35
0.0GluCys: 0.0 ± 0.0
2.364GluAsp: 2.364 ± 1.088
4.137GluGlu: 4.137 ± 1.39
1.182GluPhe: 1.182 ± 0.544
5.319GluGly: 5.319 ± 1.687
0.0GluHis: 0.0 ± 0.0
1.773GluIle: 1.773 ± 0.598
4.728GluLys: 4.728 ± 1.603
4.728GluLeu: 4.728 ± 2.236
4.728GluMet: 4.728 ± 1.289
0.591GluAsn: 0.591 ± 0.397
5.91GluPro: 5.91 ± 2.289
7.092GluGln: 7.092 ± 4.297
5.319GluArg: 5.319 ± 1.389
4.137GluSer: 4.137 ± 1.337
4.728GluThr: 4.728 ± 1.993
5.319GluVal: 5.319 ± 2.288
2.364GluTrp: 2.364 ± 1.179
3.546GluTyr: 3.546 ± 1.422
0.0GluXaa: 0.0 ± 0.0
Phe
2.364PheAla: 2.364 ± 0.753
0.0PheCys: 0.0 ± 0.0
2.364PheAsp: 2.364 ± 1.172
3.546PheGlu: 3.546 ± 1.147
1.773PhePhe: 1.773 ± 1.03
1.773PheGly: 1.773 ± 0.846
0.0PheHis: 0.0 ± 0.0
2.364PheIle: 2.364 ± 0.96
2.364PheLys: 2.364 ± 1.269
2.364PheLeu: 2.364 ± 1.14
1.773PheMet: 1.773 ± 1.03
0.0PheAsn: 0.0 ± 0.0
1.182PhePro: 1.182 ± 1.119
1.773PheGln: 1.773 ± 0.863
0.591PheArg: 0.591 ± 0.397
1.182PheSer: 1.182 ± 1.119
0.591PheThr: 0.591 ± 0.397
0.0PheVal: 0.0 ± 0.0
1.773PheTrp: 1.773 ± 0.638
1.773PheTyr: 1.773 ± 0.638
0.0PheXaa: 0.0 ± 0.0
Gly
6.501GlyAla: 6.501 ± 2.294
0.0GlyCys: 0.0 ± 0.0
3.546GlyAsp: 3.546 ± 1.985
5.319GlyGlu: 5.319 ± 1.928
1.182GlyPhe: 1.182 ± 0.749
15.957GlyGly: 15.957 ± 7.034
2.364GlyHis: 2.364 ± 1.14
3.546GlyIle: 3.546 ± 0.848
4.728GlyLys: 4.728 ± 1.389
5.91GlyLeu: 5.91 ± 1.372
2.364GlyMet: 2.364 ± 1.717
5.319GlyAsn: 5.319 ± 1.744
5.319GlyPro: 5.319 ± 3.127
0.591GlyGln: 0.591 ± 0.397
4.728GlyArg: 4.728 ± 3.175
5.91GlySer: 5.91 ± 2.285
3.546GlyThr: 3.546 ± 1.203
4.728GlyVal: 4.728 ± 1.272
1.182GlyTrp: 1.182 ± 1.034
4.137GlyTyr: 4.137 ± 1.336
0.0GlyXaa: 0.0 ± 0.0
His
2.364HisAla: 2.364 ± 0.725
1.773HisCys: 1.773 ± 1.291
1.182HisAsp: 1.182 ± 0.752
0.591HisGlu: 0.591 ± 0.559
0.0HisPhe: 0.0 ± 0.0
4.728HisGly: 4.728 ± 1.832
0.0HisHis: 0.0 ± 0.0
1.182HisIle: 1.182 ± 0.641
1.773HisLys: 1.773 ± 1.004
0.591HisLeu: 0.591 ± 0.397
0.591HisMet: 0.591 ± 0.626
0.0HisAsn: 0.0 ± 0.0
1.182HisPro: 1.182 ± 0.641
0.0HisGln: 0.0 ± 0.0
1.182HisArg: 1.182 ± 0.749
1.773HisSer: 1.773 ± 0.638
1.773HisThr: 1.773 ± 0.863
0.591HisVal: 0.591 ± 0.711
1.773HisTrp: 1.773 ± 1.262
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.955IleAla: 2.955 ± 1.22
0.0IleCys: 0.0 ± 0.0
2.364IleAsp: 2.364 ± 1.098
2.955IleGlu: 2.955 ± 1.22
0.0IlePhe: 0.0 ± 0.0
2.364IleGly: 2.364 ± 0.756
0.591IleHis: 0.591 ± 0.397
0.591IleIle: 0.591 ± 0.397
1.182IleLys: 1.182 ± 0.891
2.955IleLeu: 2.955 ± 1.007
0.591IleMet: 0.591 ± 0.626
2.364IleAsn: 2.364 ± 0.983
1.773IlePro: 1.773 ± 1.004
3.546IleGln: 3.546 ± 2.015
1.773IleArg: 1.773 ± 1.134
0.591IleSer: 0.591 ± 0.397
0.0IleThr: 0.0 ± 0.0
4.137IleVal: 4.137 ± 0.985
0.591IleTrp: 0.591 ± 0.397
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
8.865LysAla: 8.865 ± 2.87
0.0LysCys: 0.0 ± 0.0
3.546LysAsp: 3.546 ± 1.093
3.546LysGlu: 3.546 ± 1.794
2.364LysPhe: 2.364 ± 0.96
3.546LysGly: 3.546 ± 1.228
0.591LysHis: 0.591 ± 0.626
0.0LysIle: 0.0 ± 0.0
4.137LysLys: 4.137 ± 2.729
0.591LysLeu: 0.591 ± 0.397
1.773LysMet: 1.773 ± 0.846
1.182LysAsn: 1.182 ± 0.793
5.91LysPro: 5.91 ± 3.136
3.546LysGln: 3.546 ± 0.864
4.137LysArg: 4.137 ± 1.7
2.955LysSer: 2.955 ± 1.559
1.773LysThr: 1.773 ± 0.911
4.137LysVal: 4.137 ± 1.163
1.182LysTrp: 1.182 ± 1.251
2.955LysTyr: 2.955 ± 1.15
0.0LysXaa: 0.0 ± 0.0
Leu
8.865LeuAla: 8.865 ± 2.97
0.0LeuCys: 0.0 ± 0.0
2.955LeuAsp: 2.955 ± 1.622
7.683LeuGlu: 7.683 ± 1.805
2.364LeuPhe: 2.364 ± 1.566
2.955LeuGly: 2.955 ± 0.927
3.546LeuHis: 3.546 ± 1.142
0.591LeuIle: 0.591 ± 0.589
2.955LeuLys: 2.955 ± 1.202
4.728LeuLeu: 4.728 ± 1.388
1.773LeuMet: 1.773 ± 0.97
1.182LeuAsn: 1.182 ± 0.793
5.91LeuPro: 5.91 ± 2.511
1.773LeuGln: 1.773 ± 1.134
7.092LeuArg: 7.092 ± 2.044
5.319LeuSer: 5.319 ± 1.8
3.546LeuThr: 3.546 ± 1.199
4.137LeuVal: 4.137 ± 1.045
0.591LeuTrp: 0.591 ± 0.397
0.591LeuTyr: 0.591 ± 0.626
0.0LeuXaa: 0.0 ± 0.0
Met
2.364MetAla: 2.364 ± 0.756
0.0MetCys: 0.0 ± 0.0
1.773MetAsp: 1.773 ± 0.911
2.364MetGlu: 2.364 ± 1.18
0.591MetPhe: 0.591 ± 0.559
2.955MetGly: 2.955 ± 1.745
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.773MetLys: 1.773 ± 0.863
1.773MetLeu: 1.773 ± 0.846
0.0MetMet: 0.0 ± 0.0
0.591MetAsn: 0.591 ± 0.397
0.591MetPro: 0.591 ± 0.626
0.591MetGln: 0.591 ± 0.397
2.364MetArg: 2.364 ± 0.933
1.773MetSer: 1.773 ± 1.134
1.773MetThr: 1.773 ± 0.824
2.364MetVal: 2.364 ± 0.753
0.0MetTrp: 0.0 ± 0.0
1.182MetTyr: 1.182 ± 0.544
0.0MetXaa: 0.0 ± 0.0
Asn
4.137AsnAla: 4.137 ± 1.766
0.0AsnCys: 0.0 ± 0.0
1.182AsnAsp: 1.182 ± 0.57
0.591AsnGlu: 0.591 ± 0.397
1.182AsnPhe: 1.182 ± 1.114
2.955AsnGly: 2.955 ± 0.905
1.182AsnHis: 1.182 ± 0.793
0.591AsnIle: 0.591 ± 0.397
1.773AsnLys: 1.773 ± 1.004
3.546AsnLeu: 3.546 ± 1.476
0.0AsnMet: 0.0 ± 0.0
2.364AsnAsn: 2.364 ± 0.725
2.364AsnPro: 2.364 ± 1.172
0.591AsnGln: 0.591 ± 0.559
3.546AsnArg: 3.546 ± 1.924
2.364AsnSer: 2.364 ± 1.088
2.364AsnThr: 2.364 ± 1.048
0.591AsnVal: 0.591 ± 0.559
0.0AsnTrp: 0.0 ± 0.0
1.182AsnTyr: 1.182 ± 0.793
0.0AsnXaa: 0.0 ± 0.0
Pro
6.501ProAla: 6.501 ± 2.47
0.0ProCys: 0.0 ± 0.0
4.137ProAsp: 4.137 ± 1.471
5.91ProGlu: 5.91 ± 2.045
2.364ProPhe: 2.364 ± 1.282
4.137ProGly: 4.137 ± 1.832
2.364ProHis: 2.364 ± 1.269
1.773ProIle: 1.773 ± 1.004
4.137ProLys: 4.137 ± 2.55
7.683ProLeu: 7.683 ± 2.022
1.182ProMet: 1.182 ± 0.612
0.591ProAsn: 0.591 ± 0.559
3.546ProPro: 3.546 ± 2.103
1.182ProGln: 1.182 ± 0.544
5.91ProArg: 5.91 ± 2.081
4.137ProSer: 4.137 ± 2.161
4.728ProThr: 4.728 ± 2.551
8.274ProVal: 8.274 ± 2.747
1.773ProTrp: 1.773 ± 1.004
1.182ProTyr: 1.182 ± 0.612
0.0ProXaa: 0.0 ± 0.0
Gln
4.728GlnAla: 4.728 ± 2.161
0.0GlnCys: 0.0 ± 0.0
1.773GlnAsp: 1.773 ± 1.678
4.728GlnGlu: 4.728 ± 1.187
2.364GlnPhe: 2.364 ± 0.753
2.955GlnGly: 2.955 ± 2.113
0.591GlnHis: 0.591 ± 0.397
0.591GlnIle: 0.591 ± 0.397
1.773GlnLys: 1.773 ± 1.134
1.773GlnLeu: 1.773 ± 0.771
1.773GlnMet: 1.773 ± 1.203
0.0GlnAsn: 0.0 ± 0.0
1.182GlnPro: 1.182 ± 0.544
3.546GlnGln: 3.546 ± 1.633
5.91GlnArg: 5.91 ± 1.8
3.546GlnSer: 3.546 ± 2.067
1.182GlnThr: 1.182 ± 1.177
1.773GlnVal: 1.773 ± 1.203
0.591GlnTrp: 0.591 ± 0.559
1.182GlnTyr: 1.182 ± 1.119
0.0GlnXaa: 0.0 ± 0.0
Arg
8.274ArgAla: 8.274 ± 2.284
0.0ArgCys: 0.0 ± 0.0
4.728ArgAsp: 4.728 ± 2.289
7.092ArgGlu: 7.092 ± 1.958
2.364ArgPhe: 2.364 ± 1.098
2.364ArgGly: 2.364 ± 0.652
1.182ArgHis: 1.182 ± 0.749
5.91ArgIle: 5.91 ± 1.305
5.319ArgLys: 5.319 ± 2.53
6.501ArgLeu: 6.501 ± 1.54
2.364ArgMet: 2.364 ± 1.262
1.182ArgAsn: 1.182 ± 0.57
4.137ArgPro: 4.137 ± 1.5
5.91ArgGln: 5.91 ± 1.921
3.546ArgArg: 3.546 ± 0.817
5.91ArgSer: 5.91 ± 2.396
5.91ArgThr: 5.91 ± 1.268
2.364ArgVal: 2.364 ± 1.276
0.591ArgTrp: 0.591 ± 0.559
3.546ArgTyr: 3.546 ± 2.015
0.0ArgXaa: 0.0 ± 0.0
Ser
3.546SerAla: 3.546 ± 1.684
0.0SerCys: 0.0 ± 0.0
2.955SerAsp: 2.955 ± 0.632
1.773SerGlu: 1.773 ± 1.016
1.182SerPhe: 1.182 ± 0.749
7.092SerGly: 7.092 ± 2.311
1.773SerHis: 1.773 ± 1.306
2.955SerIle: 2.955 ± 1.005
2.955SerLys: 2.955 ± 1.681
3.546SerLeu: 3.546 ± 1.371
0.591SerMet: 0.591 ± 0.559
2.955SerAsn: 2.955 ± 1.114
8.865SerPro: 8.865 ± 4.192
0.591SerGln: 0.591 ± 0.397
7.683SerArg: 7.683 ± 3.021
5.91SerSer: 5.91 ± 4.161
5.319SerThr: 5.319 ± 1.744
2.955SerVal: 2.955 ± 1.169
1.773SerTrp: 1.773 ± 0.759
1.773SerTyr: 1.773 ± 0.846
0.0SerXaa: 0.0 ± 0.0
Thr
6.501ThrAla: 6.501 ± 2.95
0.0ThrCys: 0.0 ± 0.0
2.955ThrAsp: 2.955 ± 1.544
1.773ThrGlu: 1.773 ± 0.796
0.591ThrPhe: 0.591 ± 0.397
5.91ThrGly: 5.91 ± 2.164
1.773ThrHis: 1.773 ± 1.016
0.591ThrIle: 0.591 ± 0.711
1.182ThrLys: 1.182 ± 0.612
4.728ThrLeu: 4.728 ± 0.936
0.591ThrMet: 0.591 ± 0.397
1.773ThrAsn: 1.773 ± 1.004
5.319ThrPro: 5.319 ± 1.774
2.955ThrGln: 2.955 ± 1.531
4.728ThrArg: 4.728 ± 2.391
5.319ThrSer: 5.319 ± 2.95
2.364ThrThr: 2.364 ± 1.586
2.364ThrVal: 2.364 ± 1.136
0.0ThrTrp: 0.0 ± 0.0
1.773ThrTyr: 1.773 ± 1.134
0.0ThrXaa: 0.0 ± 0.0
Val
5.319ValAla: 5.319 ± 1.636
0.0ValCys: 0.0 ± 0.0
7.092ValAsp: 7.092 ± 1.412
3.546ValGlu: 3.546 ± 1.482
2.364ValPhe: 2.364 ± 0.753
2.364ValGly: 2.364 ± 1.136
2.364ValHis: 2.364 ± 0.933
0.591ValIle: 0.591 ± 0.397
1.773ValLys: 1.773 ± 1.512
6.501ValLeu: 6.501 ± 1.593
1.182ValMet: 1.182 ± 0.612
0.0ValAsn: 0.0 ± 0.0
5.319ValPro: 5.319 ± 1.908
2.364ValGln: 2.364 ± 1.179
6.501ValArg: 6.501 ± 2.285
4.728ValSer: 4.728 ± 1.349
4.137ValThr: 4.137 ± 1.482
4.728ValVal: 4.728 ± 1.395
0.591ValTrp: 0.591 ± 0.559
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
3.546TrpAla: 3.546 ± 1.39
1.182TrpCys: 1.182 ± 1.114
2.364TrpAsp: 2.364 ± 1.498
1.773TrpGlu: 1.773 ± 0.793
0.591TrpPhe: 0.591 ± 0.589
1.773TrpGly: 1.773 ± 0.884
0.591TrpHis: 0.591 ± 0.559
0.0TrpIle: 0.0 ± 0.0
0.591TrpLys: 0.591 ± 0.626
0.591TrpLeu: 0.591 ± 0.397
0.0TrpMet: 0.0 ± 0.0
2.364TrpAsn: 2.364 ± 0.886
0.591TrpPro: 0.591 ± 0.626
1.182TrpGln: 1.182 ± 1.119
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.591TrpVal: 0.591 ± 0.589
0.0TrpTrp: 0.0 ± 0.0
1.773TrpTyr: 1.773 ± 0.598
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.955TyrAla: 2.955 ± 0.612
0.0TyrCys: 0.0 ± 0.0
1.182TyrAsp: 1.182 ± 0.891
2.955TyrGlu: 2.955 ± 0.98
1.182TyrPhe: 1.182 ± 1.119
3.546TyrGly: 3.546 ± 1.732
0.0TyrHis: 0.0 ± 0.0
4.137TyrIle: 4.137 ± 1.488
1.182TyrLys: 1.182 ± 0.784
3.546TyrLeu: 3.546 ± 1.491
0.591TyrMet: 0.591 ± 0.626
2.364TyrAsn: 2.364 ± 0.725
1.182TyrPro: 1.182 ± 1.119
0.591TyrGln: 0.591 ± 0.589
1.182TyrArg: 1.182 ± 0.612
2.955TyrSer: 2.955 ± 1.251
1.182TyrThr: 1.182 ± 0.612
0.591TyrVal: 0.591 ± 0.559
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1693 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski