Amino acid dipepetide frequency for Magnetospira sp. (strain QH-2) (Marine magnetic spirillum (strain QH-2))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.652AlaAla: 12.652 ± 0.144	1.045AlaCys: 1.045 ± 0.032	6.724AlaAsp: 6.724 ± 0.105	7.195AlaGlu: 7.195 ± 0.089	3.933AlaPhe: 3.933 ± 0.067	8.514AlaGly: 8.514 ± 0.098	2.258AlaHis: 2.258 ± 0.048	4.862AlaIle: 4.862 ± 0.063	4.182AlaLys: 4.182 ± 0.074	11.823AlaLeu: 11.823 ± 0.155	3.183AlaMet: 3.183 ± 0.054	2.703AlaAsn: 2.703 ± 0.055	4.688AlaPro: 4.688 ± 0.086	3.588AlaGln: 3.588 ± 0.053	7.273AlaArg: 7.273 ± 0.101	4.843AlaSer: 4.843 ± 0.065	5.23AlaThr: 5.23 ± 0.084	7.849AlaVal: 7.849 ± 0.096	1.437AlaTrp: 1.437 ± 0.04	2.423AlaTyr: 2.423 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.885CysAla: 0.885 ± 0.028	0.103CysCys: 0.103 ± 0.01	0.576CysAsp: 0.576 ± 0.023	0.467CysGlu: 0.467 ± 0.021	0.312CysPhe: 0.312 ± 0.016	0.963CysGly: 0.963 ± 0.033	0.406CysHis: 0.406 ± 0.026	0.434CysIle: 0.434 ± 0.019	0.276CysLys: 0.276 ± 0.015	0.923CysLeu: 0.923 ± 0.028	0.201CysMet: 0.201 ± 0.013	0.23CysAsn: 0.23 ± 0.017	0.526CysPro: 0.526 ± 0.025	0.32CysGln: 0.32 ± 0.017	0.691CysArg: 0.691 ± 0.025	0.466CysSer: 0.466 ± 0.02	0.447CysThr: 0.447 ± 0.021	0.577CysVal: 0.577 ± 0.026	0.104CysTrp: 0.104 ± 0.009	0.231CysTyr: 0.231 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.636AspAla: 5.636 ± 0.084	0.599AspCys: 0.599 ± 0.023	4.075AspAsp: 4.075 ± 0.106	3.821AspGlu: 3.821 ± 0.065	2.328AspPhe: 2.328 ± 0.05	6.09AspGly: 6.09 ± 0.191	1.691AspHis: 1.691 ± 0.045	3.101AspIle: 3.101 ± 0.053	2.38AspLys: 2.38 ± 0.052	7.706AspLeu: 7.706 ± 0.083	1.788AspMet: 1.788 ± 0.04	1.716AspAsn: 1.716 ± 0.039	3.962AspPro: 3.962 ± 0.061	2.331AspGln: 2.331 ± 0.048	4.571AspArg: 4.571 ± 0.064	3.041AspSer: 3.041 ± 0.065	2.858AspThr: 2.858 ± 0.092	4.036AspVal: 4.036 ± 0.066	1.106AspTrp: 1.106 ± 0.03	1.615AspTyr: 1.615 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	7.482GluAla: 7.482 ± 0.095	0.417GluCys: 0.417 ± 0.021	3.834GluAsp: 3.834 ± 0.06	4.213GluGlu: 4.213 ± 0.069	1.83GluPhe: 1.83 ± 0.035	4.82GluGly: 4.82 ± 0.082	1.162GluHis: 1.162 ± 0.031	3.597GluIle: 3.597 ± 0.057	2.829GluLys: 2.829 ± 0.069	5.017GluLeu: 5.017 ± 0.072	1.82GluMet: 1.82 ± 0.044	1.89GluAsn: 1.89 ± 0.041	2.719GluPro: 2.719 ± 0.061	2.519GluGln: 2.519 ± 0.045	4.471GluArg: 4.471 ± 0.076	3.275GluSer: 3.275 ± 0.055	4.049GluThr: 4.049 ± 0.064	4.108GluVal: 4.108 ± 0.065	0.68GluTrp: 0.68 ± 0.027	1.121GluTyr: 1.121 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.574PheAla: 3.574 ± 0.067	0.404PheCys: 0.404 ± 0.019	2.673PheAsp: 2.673 ± 0.052	2.276PheGlu: 2.276 ± 0.045	1.425PhePhe: 1.425 ± 0.04	3.405PheGly: 3.405 ± 0.067	0.882PheHis: 0.882 ± 0.029	1.704PheIle: 1.704 ± 0.044	1.328PheLys: 1.328 ± 0.032	3.639PheLeu: 3.639 ± 0.075	0.9PheMet: 0.9 ± 0.026	1.172PheAsn: 1.172 ± 0.033	1.568PhePro: 1.568 ± 0.038	1.189PheGln: 1.189 ± 0.032	2.016PheArg: 2.016 ± 0.04	2.161PheSer: 2.161 ± 0.047	2.006PheThr: 2.006 ± 0.042	2.519PheVal: 2.519 ± 0.047	0.543PheTrp: 0.543 ± 0.027	0.905PheTyr: 0.905 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	7.957GlyAla: 7.957 ± 0.122	0.869GlyCys: 0.869 ± 0.032	5.388GlyAsp: 5.388 ± 0.136	5.056GlyGlu: 5.056 ± 0.063	3.312GlyPhe: 3.312 ± 0.054	7.598GlyGly: 7.598 ± 0.175	2.006GlyHis: 2.006 ± 0.037	4.602GlyIle: 4.602 ± 0.061	3.563GlyLys: 3.563 ± 0.068	9.261GlyLeu: 9.261 ± 0.111	2.514GlyMet: 2.514 ± 0.052	2.56GlyAsn: 2.56 ± 0.085	3.363GlyPro: 3.363 ± 0.059	3.085GlyGln: 3.085 ± 0.053	5.511GlyArg: 5.511 ± 0.075	4.67GlySer: 4.67 ± 0.107	4.752GlyThr: 4.752 ± 0.109	5.693GlyVal: 5.693 ± 0.084	1.29GlyTrp: 1.29 ± 0.039	2.344GlyTyr: 2.344 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.14HisAla: 2.14 ± 0.047	0.308HisCys: 0.308 ± 0.017	1.351HisAsp: 1.351 ± 0.035	1.218HisGlu: 1.218 ± 0.034	0.927HisPhe: 0.927 ± 0.026	2.111HisGly: 2.111 ± 0.045	0.74HisHis: 0.74 ± 0.028	1.006HisIle: 1.006 ± 0.029	0.767HisLys: 0.767 ± 0.024	2.493HisLeu: 2.493 ± 0.049	0.668HisMet: 0.668 ± 0.021	0.554HisAsn: 0.554 ± 0.022	1.515HisPro: 1.515 ± 0.041	0.823HisGln: 0.823 ± 0.025	1.625HisArg: 1.625 ± 0.041	0.97HisSer: 0.97 ± 0.03	0.949HisThr: 0.949 ± 0.03	1.528HisVal: 1.528 ± 0.037	0.407HisTrp: 0.407 ± 0.017	0.638HisTyr: 0.638 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.539IleAla: 5.539 ± 0.082	0.554IleCys: 0.554 ± 0.02	3.711IleAsp: 3.711 ± 0.058	3.379IleGlu: 3.379 ± 0.057	1.589IlePhe: 1.589 ± 0.041	4.7IleGly: 4.7 ± 0.071	1.238IleHis: 1.238 ± 0.035	2.37IleIle: 2.37 ± 0.051	1.779IleLys: 1.779 ± 0.043	4.981IleLeu: 4.981 ± 0.078	1.095IleMet: 1.095 ± 0.031	1.624IleAsn: 1.624 ± 0.033	2.616IlePro: 2.616 ± 0.048	1.519IleGln: 1.519 ± 0.041	3.04IleArg: 3.04 ± 0.048	2.768IleSer: 2.768 ± 0.055	2.707IleThr: 2.707 ± 0.051	3.373IleVal: 3.373 ± 0.059	0.651IleTrp: 0.651 ± 0.025	1.151IleTyr: 1.151 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	4.672LysAla: 4.672 ± 0.087	0.239LysCys: 0.239 ± 0.014	2.321LysAsp: 2.321 ± 0.049	2.351LysGlu: 2.351 ± 0.053	1.019LysPhe: 1.019 ± 0.028	3.251LysGly: 3.251 ± 0.067	0.735LysHis: 0.735 ± 0.025	1.904LysIle: 1.904 ± 0.048	2.024LysLys: 2.024 ± 0.068	3.417LysLeu: 3.417 ± 0.066	1.096LysMet: 1.096 ± 0.032	1.17LysAsn: 1.17 ± 0.037	2.21LysPro: 2.21 ± 0.056	1.377LysGln: 1.377 ± 0.038	2.531LysArg: 2.531 ± 0.049	2.106LysSer: 2.106 ± 0.044	2.364LysThr: 2.364 ± 0.055	2.902LysVal: 2.902 ± 0.058	0.447LysTrp: 0.447 ± 0.022	0.793LysTyr: 0.793 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	11.99LeuAla: 11.99 ± 0.116	0.877LeuCys: 0.877 ± 0.029	6.815LeuAsp: 6.815 ± 0.096	6.078LeuGlu: 6.078 ± 0.089	4.042LeuPhe: 4.042 ± 0.08	8.219LeuGly: 8.219 ± 0.104	2.188LeuHis: 2.188 ± 0.049	5.265LeuIle: 5.265 ± 0.078	4.061LeuLys: 4.061 ± 0.065	9.87LeuLeu: 9.87 ± 0.13	2.659LeuMet: 2.659 ± 0.049	2.896LeuAsn: 2.896 ± 0.05	5.514LeuPro: 5.514 ± 0.073	2.798LeuGln: 2.798 ± 0.047	6.69LeuArg: 6.69 ± 0.097	6.554LeuSer: 6.554 ± 0.072	5.799LeuThr: 5.799 ± 0.069	7.553LeuVal: 7.553 ± 0.099	1.17LeuTrp: 1.17 ± 0.029	2.249LeuTyr: 2.249 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	3.499MetAla: 3.499 ± 0.064	0.147MetCys: 0.147 ± 0.012	1.797MetAsp: 1.797 ± 0.039	1.635MetGlu: 1.635 ± 0.037	0.732MetPhe: 0.732 ± 0.027	2.362MetGly: 2.362 ± 0.05	0.449MetHis: 0.449 ± 0.02	1.481MetIle: 1.481 ± 0.035	1.105MetLys: 1.105 ± 0.033	2.4MetLeu: 2.4 ± 0.054	0.793MetMet: 0.793 ± 0.028	0.856MetAsn: 0.856 ± 0.027	1.441MetPro: 1.441 ± 0.035	0.796MetGln: 0.796 ± 0.026	1.569MetArg: 1.569 ± 0.042	1.579MetSer: 1.579 ± 0.036	1.976MetThr: 1.976 ± 0.04	2.293MetVal: 2.293 ± 0.04	0.211MetTrp: 0.211 ± 0.014	0.386MetTyr: 0.386 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.79AsnAla: 2.79 ± 0.055	0.282AsnCys: 0.282 ± 0.016	1.822AsnAsp: 1.822 ± 0.078	1.505AsnGlu: 1.505 ± 0.042	1.014AsnPhe: 1.014 ± 0.032	2.62AsnGly: 2.62 ± 0.066	0.648AsnHis: 0.648 ± 0.024	1.423AsnIle: 1.423 ± 0.038	1.132AsnLys: 1.132 ± 0.036	3.155AsnLeu: 3.155 ± 0.05	0.774AsnMet: 0.774 ± 0.028	0.84AsnAsn: 0.84 ± 0.031	1.964AsnPro: 1.964 ± 0.047	0.983AsnGln: 0.983 ± 0.031	1.992AsnArg: 1.992 ± 0.044	1.273AsnSer: 1.273 ± 0.035	1.342AsnThr: 1.342 ± 0.039	1.816AsnVal: 1.816 ± 0.044	0.403AsnTrp: 0.403 ± 0.02	0.648AsnTyr: 0.648 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	4.787ProAla: 4.787 ± 0.077	0.4ProCys: 0.4 ± 0.022	3.918ProAsp: 3.918 ± 0.061	4.014ProGlu: 4.014 ± 0.074	1.936ProPhe: 1.936 ± 0.045	4.279ProGly: 4.279 ± 0.063	1.114ProHis: 1.114 ± 0.034	2.229ProIle: 2.229 ± 0.048	2.088ProLys: 2.088 ± 0.047	4.995ProLeu: 4.995 ± 0.066	1.362ProMet: 1.362 ± 0.036	1.348ProAsn: 1.348 ± 0.034	2.733ProPro: 2.733 ± 0.074	1.514ProGln: 1.514 ± 0.04	2.626ProArg: 2.626 ± 0.053	2.619ProSer: 2.619 ± 0.058	2.651ProThr: 2.651 ± 0.049	4.136ProVal: 4.136 ± 0.058	0.74ProTrp: 0.74 ± 0.027	1.239ProTyr: 1.239 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.465GlnAla: 4.465 ± 0.068	0.241GlnCys: 0.241 ± 0.014	1.777GlnAsp: 1.777 ± 0.042	1.87GlnGlu: 1.87 ± 0.044	1.06GlnPhe: 1.06 ± 0.033	2.829GlnGly: 2.829 ± 0.058	0.542GlnHis: 0.542 ± 0.022	1.647GlnIle: 1.647 ± 0.035	1.277GlnLys: 1.277 ± 0.036	2.766GlnLeu: 2.766 ± 0.05	0.977GlnMet: 0.977 ± 0.031	0.85GlnAsn: 0.85 ± 0.029	1.752GlnPro: 1.752 ± 0.044	1.22GlnGln: 1.22 ± 0.04	2.366GlnArg: 2.366 ± 0.05	1.889GlnSer: 1.889 ± 0.039	1.823GlnThr: 1.823 ± 0.044	2.7GlnVal: 2.7 ± 0.054	0.516GlnTrp: 0.516 ± 0.021	0.704GlnTyr: 0.704 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	6.303ArgAla: 6.303 ± 0.09	0.564ArgCys: 0.564 ± 0.022	4.27ArgAsp: 4.27 ± 0.08	4.035ArgGlu: 4.035 ± 0.068	2.601ArgPhe: 2.601 ± 0.049	4.368ArgGly: 4.368 ± 0.065	1.783ArgHis: 1.783 ± 0.037	3.682ArgIle: 3.682 ± 0.056	2.632ArgLys: 2.632 ± 0.06	7.46ArgLeu: 7.46 ± 0.115	1.971ArgMet: 1.971 ± 0.046	1.846ArgAsn: 1.846 ± 0.04	3.158ArgPro: 3.158 ± 0.067	2.513ArgGln: 2.513 ± 0.05	5.079ArgArg: 5.079 ± 0.087	3.228ArgSer: 3.228 ± 0.067	3.148ArgThr: 3.148 ± 0.054	4.482ArgVal: 4.482 ± 0.068	0.897ArgTrp: 0.897 ± 0.026	1.657ArgTyr: 1.657 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	5.055SerAla: 5.055 ± 0.067	0.486SerCys: 0.486 ± 0.024	3.195SerAsp: 3.195 ± 0.079	3.008SerGlu: 3.008 ± 0.056	2.133SerPhe: 2.133 ± 0.038	5.286SerGly: 5.286 ± 0.098	1.287SerHis: 1.287 ± 0.03	2.54SerIle: 2.54 ± 0.045	1.991SerLys: 1.991 ± 0.049	5.9SerLeu: 5.9 ± 0.068	1.497SerMet: 1.497 ± 0.039	1.494SerAsn: 1.494 ± 0.035	2.676SerPro: 2.676 ± 0.046	1.707SerGln: 1.707 ± 0.039	3.328SerArg: 3.328 ± 0.062	2.781SerSer: 2.781 ± 0.056	2.48SerThr: 2.48 ± 0.06	3.892SerVal: 3.892 ± 0.064	0.726SerTrp: 0.726 ± 0.025	1.345SerTyr: 1.345 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.468ThrAla: 5.468 ± 0.091	0.51ThrCys: 0.51 ± 0.022	3.396ThrAsp: 3.396 ± 0.086	3.077ThrGlu: 3.077 ± 0.057	2.007ThrPhe: 2.007 ± 0.041	5.143ThrGly: 5.143 ± 0.092	1.172ThrHis: 1.172 ± 0.033	2.836ThrIle: 2.836 ± 0.059	1.782ThrLys: 1.782 ± 0.047	6.116ThrLeu: 6.116 ± 0.086	1.272ThrMet: 1.272 ± 0.03	1.434ThrAsn: 1.434 ± 0.034	3.148ThrPro: 3.148 ± 0.05	1.618ThrGln: 1.618 ± 0.04	3.074ThrArg: 3.074 ± 0.056	2.565ThrSer: 2.565 ± 0.056	2.697ThrThr: 2.697 ± 0.066	4.284ThrVal: 4.284 ± 0.08	0.76ThrTrp: 0.76 ± 0.032	1.311ThrTyr: 1.311 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	8.169ValAla: 8.169 ± 0.097	0.71ValCys: 0.71 ± 0.027	4.483ValAsp: 4.483 ± 0.065	4.571ValGlu: 4.571 ± 0.056	2.621ValPhe: 2.621 ± 0.061	5.576ValGly: 5.576 ± 0.073	1.465ValHis: 1.465 ± 0.038	4.032ValIle: 4.032 ± 0.063	2.397ValLys: 2.397 ± 0.053	7.379ValLeu: 7.379 ± 0.097	1.912ValMet: 1.912 ± 0.037	2.087ValAsn: 2.087 ± 0.051	3.474ValPro: 3.474 ± 0.065	2.024ValGln: 2.024 ± 0.041	4.407ValArg: 4.407 ± 0.07	4.062ValSer: 4.062 ± 0.059	4.576ValThr: 4.576 ± 0.079	5.877ValVal: 5.877 ± 0.08	0.862ValTrp: 0.862 ± 0.031	1.524ValTyr: 1.524 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.238TrpAla: 1.238 ± 0.036	0.138TrpCys: 0.138 ± 0.011	0.735TrpAsp: 0.735 ± 0.029	0.742TrpGlu: 0.742 ± 0.023	0.512TrpPhe: 0.512 ± 0.021	0.989TrpGly: 0.989 ± 0.036	0.346TrpHis: 0.346 ± 0.017	0.731TrpIle: 0.731 ± 0.024	0.525TrpLys: 0.525 ± 0.02	1.489TrpLeu: 1.489 ± 0.041	0.409TrpMet: 0.409 ± 0.019	0.469TrpAsn: 0.469 ± 0.02	0.612TrpPro: 0.612 ± 0.024	0.524TrpGln: 0.524 ± 0.02	1.021TrpArg: 1.021 ± 0.028	0.813TrpSer: 0.813 ± 0.027	0.784TrpThr: 0.784 ± 0.023	0.936TrpVal: 0.936 ± 0.03	0.244TrpTrp: 0.244 ± 0.015	0.318TrpTyr: 0.318 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.107TyrAla: 2.107 ± 0.04	0.242TyrCys: 0.242 ± 0.015	1.589TyrAsp: 1.589 ± 0.04	1.341TyrGlu: 1.341 ± 0.036	0.955TyrPhe: 0.955 ± 0.033	2.272TyrGly: 2.272 ± 0.054	0.628TyrHis: 0.628 ± 0.025	0.937TyrIle: 0.937 ± 0.03	0.811TyrLys: 0.811 ± 0.026	2.5TyrLeu: 2.5 ± 0.054	0.616TyrMet: 0.616 ± 0.023	0.686TyrAsn: 0.686 ± 0.026	1.092TyrPro: 1.092 ± 0.035	0.821TyrGln: 0.821 ± 0.027	1.795TyrArg: 1.795 ± 0.041	1.146TyrSer: 1.146 ± 0.033	1.03TyrThr: 1.03 ± 0.044	1.654TyrVal: 1.654 ± 0.04	0.379TyrTrp: 0.379 ± 0.02	0.657TyrTyr: 0.657 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3700 proteins (1196687 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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