Amino acid dipepetide frequency for Gryllus bimaculatus nudivirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.161AlaAla: 1.161 ± 0.268
0.697AlaCys: 0.697 ± 0.171
1.493AlaAsp: 1.493 ± 0.236
1.46AlaGlu: 1.46 ± 0.211
2.19AlaPhe: 2.19 ± 0.269
0.564AlaGly: 0.564 ± 0.129
0.431AlaHis: 0.431 ± 0.126
2.986AlaIle: 2.986 ± 0.256
2.223AlaLys: 2.223 ± 0.267
3.218AlaLeu: 3.218 ± 0.318
0.332AlaMet: 0.332 ± 0.105
1.791AlaAsn: 1.791 ± 0.265
1.062AlaPro: 1.062 ± 0.197
0.829AlaGln: 0.829 ± 0.144
0.763AlaArg: 0.763 ± 0.148
2.389AlaSer: 2.389 ± 0.319
1.725AlaThr: 1.725 ± 0.305
1.957AlaVal: 1.957 ± 0.293
0.232AlaTrp: 0.232 ± 0.096
1.427AlaTyr: 1.427 ± 0.258
0.0AlaXaa: 0.0 ± 0.0
Cys
0.597CysAla: 0.597 ± 0.138
0.697CysCys: 0.697 ± 0.171
1.493CysAsp: 1.493 ± 0.236
1.194CysGlu: 1.194 ± 0.244
1.294CysPhe: 1.294 ± 0.223
0.829CysGly: 0.829 ± 0.179
0.332CysHis: 0.332 ± 0.102
2.09CysIle: 2.09 ± 0.259
2.09CysLys: 2.09 ± 0.316
2.057CysLeu: 2.057 ± 0.294
0.531CysMet: 0.531 ± 0.123
1.858CysAsn: 1.858 ± 0.29
0.763CysPro: 0.763 ± 0.151
0.697CysGln: 0.697 ± 0.134
0.863CysArg: 0.863 ± 0.184
1.825CysSer: 1.825 ± 0.218
0.929CysThr: 0.929 ± 0.17
1.626CysVal: 1.626 ± 0.205
0.1CysTrp: 0.1 ± 0.056
1.062CysTyr: 1.062 ± 0.202
0.0CysXaa: 0.0 ± 0.0
Asp
2.156AspAla: 2.156 ± 0.284
1.095AspCys: 1.095 ± 0.169
3.45AspAsp: 3.45 ± 0.4
4.313AspGlu: 4.313 ± 0.448
2.82AspPhe: 2.82 ± 0.362
2.19AspGly: 2.19 ± 0.38
0.531AspHis: 0.531 ± 0.116
5.142AspIle: 5.142 ± 0.404
4.445AspLys: 4.445 ± 0.371
4.545AspLeu: 4.545 ± 0.406
0.829AspMet: 0.829 ± 0.187
5.175AspAsn: 5.175 ± 0.35
1.227AspPro: 1.227 ± 0.227
1.327AspGln: 1.327 ± 0.198
1.592AspArg: 1.592 ± 0.194
4.479AspSer: 4.479 ± 0.445
3.318AspThr: 3.318 ± 0.304
3.085AspVal: 3.085 ± 0.364
0.464AspTrp: 0.464 ± 0.118
2.588AspTyr: 2.588 ± 0.273
0.0AspXaa: 0.0 ± 0.0
Glu
1.626GluAla: 1.626 ± 0.255
1.294GluCys: 1.294 ± 0.195
3.55GluAsp: 3.55 ± 0.399
5.972GluGlu: 5.972 ± 0.812
3.085GluPhe: 3.085 ± 0.285
1.36GluGly: 1.36 ± 0.212
1.36GluHis: 1.36 ± 0.197
5.839GluIle: 5.839 ± 0.563
6.768GluLys: 6.768 ± 0.617
4.611GluLeu: 4.611 ± 0.417
1.227GluMet: 1.227 ± 0.188
6.768GluAsn: 6.768 ± 0.47
1.36GluPro: 1.36 ± 0.198
2.024GluGln: 2.024 ± 0.317
2.521GluArg: 2.521 ± 0.277
4.313GluSer: 4.313 ± 0.362
4.114GluThr: 4.114 ± 0.366
1.626GluVal: 1.626 ± 0.2
0.365GluTrp: 0.365 ± 0.102
3.483GluTyr: 3.483 ± 0.297
0.0GluXaa: 0.0 ± 0.0
Phe
1.493PheAla: 1.493 ± 0.229
1.559PheCys: 1.559 ± 0.251
3.318PheAsp: 3.318 ± 0.316
2.787PheGlu: 2.787 ± 0.264
2.953PhePhe: 2.953 ± 0.451
1.526PheGly: 1.526 ± 0.233
1.194PheHis: 1.194 ± 0.212
5.64PheIle: 5.64 ± 0.503
5.772PheLys: 5.772 ± 0.464
5.209PheLeu: 5.209 ± 0.401
1.227PheMet: 1.227 ± 0.211
4.313PheAsn: 4.313 ± 0.381
2.09PhePro: 2.09 ± 0.236
1.791PheGln: 1.791 ± 0.222
1.161PheArg: 1.161 ± 0.153
3.881PheSer: 3.881 ± 0.31
3.318PheThr: 3.318 ± 0.43
3.384PheVal: 3.384 ± 0.318
0.332PheTrp: 0.332 ± 0.113
3.649PheTyr: 3.649 ± 0.472
0.0PheXaa: 0.0 ± 0.0
Gly
0.763GlyAla: 0.763 ± 0.135
0.664GlyCys: 0.664 ± 0.11
1.227GlyAsp: 1.227 ± 0.182
1.327GlyGlu: 1.327 ± 0.204
1.692GlyPhe: 1.692 ± 0.206
0.995GlyGly: 0.995 ± 0.239
0.332GlyHis: 0.332 ± 0.096
2.919GlyIle: 2.919 ± 0.34
2.687GlyLys: 2.687 ± 0.261
2.355GlyLeu: 2.355 ± 0.345
0.597GlyMet: 0.597 ± 0.124
1.858GlyAsn: 1.858 ± 0.242
0.929GlyPro: 0.929 ± 0.181
0.796GlyGln: 0.796 ± 0.253
0.796GlyArg: 0.796 ± 0.174
2.156GlySer: 2.156 ± 0.308
1.692GlyThr: 1.692 ± 0.269
1.791GlyVal: 1.791 ± 0.308
0.232GlyTrp: 0.232 ± 0.098
1.559GlyTyr: 1.559 ± 0.3
0.0GlyXaa: 0.0 ± 0.0
His
0.431HisAla: 0.431 ± 0.115
0.232HisCys: 0.232 ± 0.076
0.796HisAsp: 0.796 ± 0.155
1.128HisGlu: 1.128 ± 0.194
1.062HisPhe: 1.062 ± 0.198
0.796HisGly: 0.796 ± 0.145
0.564HisHis: 0.564 ± 0.155
1.36HisIle: 1.36 ± 0.247
1.493HisLys: 1.493 ± 0.253
1.427HisLeu: 1.427 ± 0.166
0.265HisMet: 0.265 ± 0.092
1.261HisAsn: 1.261 ± 0.213
0.498HisPro: 0.498 ± 0.151
0.531HisGln: 0.531 ± 0.123
0.464HisArg: 0.464 ± 0.111
1.393HisSer: 1.393 ± 0.204
1.261HisThr: 1.261 ± 0.218
1.327HisVal: 1.327 ± 0.226
0.166HisTrp: 0.166 ± 0.076
1.095HisTyr: 1.095 ± 0.2
0.0HisXaa: 0.0 ± 0.0
Ile
2.919IleAla: 2.919 ± 0.32
2.156IleCys: 2.156 ± 0.28
5.076IleAsp: 5.076 ± 0.376
5.64IleGlu: 5.64 ± 0.398
4.678IlePhe: 4.678 ± 0.322
1.692IleGly: 1.692 ± 0.204
2.156IleHis: 2.156 ± 0.282
8.592IleIle: 8.592 ± 0.573
8.758IleLys: 8.758 ± 0.517
9.986IleLeu: 9.986 ± 0.483
1.891IleMet: 1.891 ± 0.241
9.654IleAsn: 9.654 ± 0.623
2.787IlePro: 2.787 ± 0.331
3.152IleGln: 3.152 ± 0.34
2.521IleArg: 2.521 ± 0.253
6.37IleSer: 6.37 ± 0.528
5.573IleThr: 5.573 ± 0.399
4.645IleVal: 4.645 ± 0.443
0.531IleTrp: 0.531 ± 0.124
5.507IleTyr: 5.507 ± 0.923
0.0IleXaa: 0.0 ± 0.0
Lys
1.825LysAla: 1.825 ± 0.238
2.256LysCys: 2.256 ± 0.294
4.379LysAsp: 4.379 ± 0.341
6.403LysGlu: 6.403 ± 0.526
4.412LysPhe: 4.412 ± 0.392
2.19LysGly: 2.19 ± 0.24
2.024LysHis: 2.024 ± 0.282
9.919LysIle: 9.919 ± 0.595
10.417LysLys: 10.417 ± 0.718
8.062LysLeu: 8.062 ± 0.636
1.891LysMet: 1.891 ± 0.21
10.782LysAsn: 10.782 ± 0.58
2.389LysPro: 2.389 ± 0.283
3.019LysGln: 3.019 ± 0.272
3.915LysArg: 3.915 ± 0.348
5.54LysSer: 5.54 ± 0.43
5.706LysThr: 5.706 ± 0.421
2.787LysVal: 2.787 ± 0.306
0.166LysTrp: 0.166 ± 0.076
5.673LysTyr: 5.673 ± 0.441
0.0LysXaa: 0.0 ± 0.0
Leu
2.422LeuAla: 2.422 ± 0.328
2.488LeuCys: 2.488 ± 0.262
4.678LeuAsp: 4.678 ± 0.338
4.313LeuGlu: 4.313 ± 0.517
5.507LeuPhe: 5.507 ± 0.467
2.588LeuGly: 2.588 ± 0.295
1.858LeuHis: 1.858 ± 0.254
7.796LeuIle: 7.796 ± 0.615
8.924LeuLys: 8.924 ± 0.691
9.289LeuLeu: 9.289 ± 0.631
1.659LeuMet: 1.659 ± 0.239
9.057LeuAsn: 9.057 ± 0.609
3.682LeuPro: 3.682 ± 0.355
4.014LeuGln: 4.014 ± 0.413
2.322LeuArg: 2.322 ± 0.275
7.166LeuSer: 7.166 ± 0.485
4.943LeuThr: 4.943 ± 0.399
3.881LeuVal: 3.881 ± 0.293
0.863LeuTrp: 0.863 ± 0.151
5.573LeuTyr: 5.573 ± 0.464
0.0LeuXaa: 0.0 ± 0.0
Met
0.398MetAla: 0.398 ± 0.107
0.365MetCys: 0.365 ± 0.155
0.929MetAsp: 0.929 ± 0.156
1.194MetGlu: 1.194 ± 0.199
1.36MetPhe: 1.36 ± 0.209
0.431MetGly: 0.431 ± 0.105
0.431MetHis: 0.431 ± 0.115
1.626MetIle: 1.626 ± 0.224
1.592MetLys: 1.592 ± 0.257
1.393MetLeu: 1.393 ± 0.247
0.564MetMet: 0.564 ± 0.123
1.161MetAsn: 1.161 ± 0.185
0.531MetPro: 0.531 ± 0.135
0.398MetGln: 0.398 ± 0.111
0.431MetArg: 0.431 ± 0.119
1.692MetSer: 1.692 ± 0.272
1.393MetThr: 1.393 ± 0.22
0.365MetVal: 0.365 ± 0.106
0.066MetTrp: 0.066 ± 0.043
1.062MetTyr: 1.062 ± 0.189
0.0MetXaa: 0.0 ± 0.0
Asn
2.554AsnAla: 2.554 ± 0.296
1.858AsnCys: 1.858 ± 0.246
5.772AsnAsp: 5.772 ± 0.495
7.066AsnGlu: 7.066 ± 0.51
4.81AsnPhe: 4.81 ± 0.491
2.654AsnGly: 2.654 ± 0.33
0.863AsnHis: 0.863 ± 0.208
9.886AsnIle: 9.886 ± 0.618
8.891AsnLys: 8.891 ± 0.519
8.725AsnLeu: 8.725 ± 0.538
1.095AsnMet: 1.095 ± 0.159
7.365AsnAsn: 7.365 ± 0.561
1.991AsnPro: 1.991 ± 0.249
2.389AsnGln: 2.389 ± 0.385
2.289AsnArg: 2.289 ± 0.31
6.436AsnSer: 6.436 ± 0.484
4.545AsnThr: 4.545 ± 0.326
6.668AsnVal: 6.668 ± 0.582
0.564AsnTrp: 0.564 ± 0.134
4.313AsnTyr: 4.313 ± 0.361
0.0AsnXaa: 0.0 ± 0.0
Pro
0.63ProAla: 0.63 ± 0.136
0.829ProCys: 0.829 ± 0.163
1.659ProAsp: 1.659 ± 0.241
2.024ProGlu: 2.024 ± 0.273
1.427ProPhe: 1.427 ± 0.182
0.896ProGly: 0.896 ± 0.178
0.564ProHis: 0.564 ± 0.114
2.355ProIle: 2.355 ± 0.231
2.588ProLys: 2.588 ± 0.287
3.218ProLeu: 3.218 ± 0.313
0.332ProMet: 0.332 ± 0.087
2.488ProAsn: 2.488 ± 0.314
1.161ProPro: 1.161 ± 0.289
0.697ProGln: 0.697 ± 0.154
0.796ProArg: 0.796 ± 0.148
2.521ProSer: 2.521 ± 0.297
1.725ProThr: 1.725 ± 0.232
1.991ProVal: 1.991 ± 0.249
0.299ProTrp: 0.299 ± 0.107
1.791ProTyr: 1.791 ± 0.239
0.0ProXaa: 0.0 ± 0.0
Gln
0.962GlnAla: 0.962 ± 0.164
0.697GlnCys: 0.697 ± 0.139
1.427GlnAsp: 1.427 ± 0.247
2.09GlnGlu: 2.09 ± 0.235
1.46GlnPhe: 1.46 ± 0.177
0.796GlnGly: 0.796 ± 0.19
0.863GlnHis: 0.863 ± 0.169
2.72GlnIle: 2.72 ± 0.258
3.019GlnLys: 3.019 ± 0.434
2.588GlnLeu: 2.588 ± 0.343
0.498GlnMet: 0.498 ± 0.135
3.251GlnAsn: 3.251 ± 0.397
0.896GlnPro: 0.896 ± 0.172
1.427GlnGln: 1.427 ± 0.306
0.962GlnArg: 0.962 ± 0.21
2.19GlnSer: 2.19 ± 0.282
1.791GlnThr: 1.791 ± 0.231
1.327GlnVal: 1.327 ± 0.2
0.166GlnTrp: 0.166 ± 0.07
1.194GlnTyr: 1.194 ± 0.191
0.0GlnXaa: 0.0 ± 0.0
Arg
0.763ArgAla: 0.763 ± 0.142
0.597ArgCys: 0.597 ± 0.127
1.427ArgAsp: 1.427 ± 0.217
1.427ArgGlu: 1.427 ± 0.239
1.791ArgPhe: 1.791 ± 0.294
0.896ArgGly: 0.896 ± 0.189
0.498ArgHis: 0.498 ± 0.151
2.953ArgIle: 2.953 ± 0.266
2.919ArgLys: 2.919 ± 0.331
2.953ArgLeu: 2.953 ± 0.299
0.863ArgMet: 0.863 ± 0.153
3.052ArgAsn: 3.052 ± 0.3
0.564ArgPro: 0.564 ± 0.115
0.763ArgGln: 0.763 ± 0.175
1.692ArgArg: 1.692 ± 0.27
2.72ArgSer: 2.72 ± 0.751
1.692ArgThr: 1.692 ± 0.31
1.526ArgVal: 1.526 ± 0.237
0.133ArgTrp: 0.133 ± 0.068
1.891ArgTyr: 1.891 ± 0.248
0.0ArgXaa: 0.0 ± 0.0
Ser
2.455SerAla: 2.455 ± 0.372
1.659SerCys: 1.659 ± 0.22
4.578SerAsp: 4.578 ± 0.39
5.043SerGlu: 5.043 ± 0.538
4.91SerPhe: 4.91 ± 0.375
2.19SerGly: 2.19 ± 0.308
1.028SerHis: 1.028 ± 0.184
5.374SerIle: 5.374 ± 0.394
6.469SerLys: 6.469 ± 0.442
6.967SerLeu: 6.967 ± 0.485
1.095SerMet: 1.095 ± 0.186
5.64SerAsn: 5.64 ± 0.437
2.223SerPro: 2.223 ± 0.294
2.057SerGln: 2.057 ± 0.275
3.118SerArg: 3.118 ± 0.792
7.863SerSer: 7.863 ± 0.591
4.877SerThr: 4.877 ± 0.393
4.678SerVal: 4.678 ± 0.4
0.464SerTrp: 0.464 ± 0.118
3.45SerTyr: 3.45 ± 0.326
0.0SerXaa: 0.0 ± 0.0
Thr
2.156ThrAla: 2.156 ± 0.27
1.36ThrCys: 1.36 ± 0.238
3.45ThrAsp: 3.45 ± 0.353
3.848ThrGlu: 3.848 ± 0.315
4.346ThrPhe: 4.346 ± 0.421
1.692ThrGly: 1.692 ± 0.216
1.028ThrHis: 1.028 ± 0.17
5.341ThrIle: 5.341 ± 0.441
4.412ThrLys: 4.412 ± 0.305
5.441ThrLeu: 5.441 ± 0.419
0.796ThrMet: 0.796 ± 0.119
5.308ThrAsn: 5.308 ± 0.381
1.725ThrPro: 1.725 ± 0.206
1.692ThrGln: 1.692 ± 0.21
1.659ThrArg: 1.659 ± 0.228
4.346ThrSer: 4.346 ± 0.382
4.445ThrThr: 4.445 ± 0.491
3.716ThrVal: 3.716 ± 0.388
0.299ThrTrp: 0.299 ± 0.099
2.455ThrTyr: 2.455 ± 0.26
0.0ThrXaa: 0.0 ± 0.0
Val
1.957ValAla: 1.957 ± 0.247
0.995ValCys: 0.995 ± 0.171
2.621ValAsp: 2.621 ± 0.33
2.554ValGlu: 2.554 ± 0.288
3.318ValPhe: 3.318 ± 0.336
1.493ValGly: 1.493 ± 0.282
0.63ValHis: 0.63 ± 0.14
5.142ValIle: 5.142 ± 0.408
4.445ValLys: 4.445 ± 0.405
5.54ValLeu: 5.54 ± 0.413
0.796ValMet: 0.796 ± 0.165
4.578ValAsn: 4.578 ± 0.4
2.09ValPro: 2.09 ± 0.264
1.227ValGln: 1.227 ± 0.214
1.526ValArg: 1.526 ± 0.23
4.777ValSer: 4.777 ± 0.374
3.118ValThr: 3.118 ± 0.366
2.72ValVal: 2.72 ± 0.335
0.299ValTrp: 0.299 ± 0.111
2.754ValTyr: 2.754 ± 0.28
0.0ValXaa: 0.0 ± 0.0
Trp
0.166TrpAla: 0.166 ± 0.072
0.265TrpCys: 0.265 ± 0.094
0.531TrpAsp: 0.531 ± 0.119
0.398TrpGlu: 0.398 ± 0.136
0.464TrpPhe: 0.464 ± 0.132
0.232TrpGly: 0.232 ± 0.09
0.0TrpHis: 0.0 ± 0.0
0.299TrpIle: 0.299 ± 0.085
0.73TrpLys: 0.73 ± 0.16
0.431TrpLeu: 0.431 ± 0.101
0.199TrpMet: 0.199 ± 0.073
0.332TrpAsn: 0.332 ± 0.082
0.299TrpPro: 0.299 ± 0.094
0.166TrpGln: 0.166 ± 0.071
0.199TrpArg: 0.199 ± 0.079
0.597TrpSer: 0.597 ± 0.136
0.365TrpThr: 0.365 ± 0.113
0.066TrpVal: 0.066 ± 0.046
0.066TrpTrp: 0.066 ± 0.059
0.398TrpTyr: 0.398 ± 0.107
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.526TyrAla: 1.526 ± 0.203
1.161TyrCys: 1.161 ± 0.171
2.919TyrAsp: 2.919 ± 0.367
3.085TyrGlu: 3.085 ± 0.333
3.019TyrPhe: 3.019 ± 0.335
1.36TyrGly: 1.36 ± 0.192
0.863TyrHis: 0.863 ± 0.18
6.303TyrIle: 6.303 ± 0.94
5.109TyrLys: 5.109 ± 0.423
5.009TyrLeu: 5.009 ± 0.438
0.664TyrMet: 0.664 ± 0.136
5.043TyrAsn: 5.043 ± 0.53
1.725TyrPro: 1.725 ± 0.237
1.327TyrGln: 1.327 ± 0.239
1.526TyrArg: 1.526 ± 0.182
3.483TyrSer: 3.483 ± 0.347
2.986TyrThr: 2.986 ± 0.359
3.417TyrVal: 3.417 ± 0.326
0.398TyrTrp: 0.398 ± 0.098
2.621TyrTyr: 2.621 ± 0.239
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 98 proteins (30144 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski