Amino acid dipepetide frequency for Mucilaginibacter corticis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.949AlaAla: 6.949 ± 0.082	0.699AlaCys: 0.699 ± 0.023	5.153AlaAsp: 5.153 ± 0.068	4.297AlaGlu: 4.297 ± 0.073	3.609AlaPhe: 3.609 ± 0.05	6.04AlaGly: 6.04 ± 0.065	1.364AlaHis: 1.364 ± 0.029	5.808AlaIle: 5.808 ± 0.072	5.099AlaLys: 5.099 ± 0.072	7.208AlaLeu: 7.208 ± 0.083	1.796AlaMet: 1.796 ± 0.037	3.941AlaAsn: 3.941 ± 0.059	2.573AlaPro: 2.573 ± 0.043	3.154AlaGln: 3.154 ± 0.05	2.551AlaArg: 2.551 ± 0.043	4.332AlaSer: 4.332 ± 0.047	4.416AlaThr: 4.416 ± 0.066	5.177AlaVal: 5.177 ± 0.058	0.83AlaTrp: 0.83 ± 0.025	3.054AlaTyr: 3.054 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.537CysAla: 0.537 ± 0.019	0.148CysCys: 0.148 ± 0.01	0.418CysAsp: 0.418 ± 0.017	0.348CysGlu: 0.348 ± 0.017	0.446CysPhe: 0.446 ± 0.019	0.613CysGly: 0.613 ± 0.022	0.196CysHis: 0.196 ± 0.011	0.576CysIle: 0.576 ± 0.022	0.496CysLys: 0.496 ± 0.018	0.853CysLeu: 0.853 ± 0.022	0.183CysMet: 0.183 ± 0.011	0.378CysAsn: 0.378 ± 0.017	0.324CysPro: 0.324 ± 0.016	0.219CysGln: 0.219 ± 0.011	0.323CysArg: 0.323 ± 0.016	0.523CysSer: 0.523 ± 0.02	0.437CysThr: 0.437 ± 0.017	0.485CysVal: 0.485 ± 0.018	0.09CysTrp: 0.09 ± 0.008	0.335CysTyr: 0.335 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.263AspAla: 4.263 ± 0.05	0.41AspCys: 0.41 ± 0.018	3.012AspAsp: 3.012 ± 0.052	3.455AspGlu: 3.455 ± 0.05	3.091AspPhe: 3.091 ± 0.044	4.021AspGly: 4.021 ± 0.059	1.22AspHis: 1.22 ± 0.029	4.095AspIle: 4.095 ± 0.052	4.177AspLys: 4.177 ± 0.056	5.208AspLeu: 5.208 ± 0.06	1.267AspMet: 1.267 ± 0.033	2.946AspAsn: 2.946 ± 0.049	2.373AspPro: 2.373 ± 0.045	2.022AspGln: 2.022 ± 0.032	2.168AspArg: 2.168 ± 0.036	3.056AspSer: 3.056 ± 0.051	2.94AspThr: 2.94 ± 0.044	3.662AspVal: 3.662 ± 0.047	0.817AspTrp: 0.817 ± 0.023	2.569AspTyr: 2.569 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	3.986GluAla: 3.986 ± 0.063	0.316GluCys: 0.316 ± 0.014	2.61GluAsp: 2.61 ± 0.047	3.003GluGlu: 3.003 ± 0.066	2.279GluPhe: 2.279 ± 0.041	3.005GluGly: 3.005 ± 0.05	1.13GluHis: 1.13 ± 0.027	4.055GluIle: 4.055 ± 0.061	4.246GluLys: 4.246 ± 0.068	5.371GluLeu: 5.371 ± 0.063	1.32GluMet: 1.32 ± 0.031	2.925GluAsn: 2.925 ± 0.041	1.739GluPro: 1.739 ± 0.034	2.368GluGln: 2.368 ± 0.043	2.351GluArg: 2.351 ± 0.046	2.587GluSer: 2.587 ± 0.04	2.818GluThr: 2.818 ± 0.046	3.417GluVal: 3.417 ± 0.056	0.634GluTrp: 0.634 ± 0.018	1.912GluTyr: 1.912 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.624PheAla: 3.624 ± 0.051	0.497PheCys: 0.497 ± 0.02	3.027PheAsp: 3.027 ± 0.045	2.599PheGlu: 2.599 ± 0.045	2.444PhePhe: 2.444 ± 0.044	3.3PheGly: 3.3 ± 0.046	0.863PheHis: 0.863 ± 0.02	3.57PheIle: 3.57 ± 0.057	3.441PheLys: 3.441 ± 0.053	4.201PheLeu: 4.201 ± 0.06	1.083PheMet: 1.083 ± 0.028	2.989PheAsn: 2.989 ± 0.047	1.714PhePro: 1.714 ± 0.03	1.2PheGln: 1.2 ± 0.028	1.691PheArg: 1.691 ± 0.035	3.373PheSer: 3.373 ± 0.049	3.226PheThr: 3.226 ± 0.049	2.819PheVal: 2.819 ± 0.043	0.606PheTrp: 0.606 ± 0.023	2.118PheTyr: 2.118 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	4.75GlyAla: 4.75 ± 0.078	0.589GlyCys: 0.589 ± 0.022	3.742GlyAsp: 3.742 ± 0.056	3.274GlyGlu: 3.274 ± 0.05	3.643GlyPhe: 3.643 ± 0.057	4.913GlyGly: 4.913 ± 0.067	1.305GlyHis: 1.305 ± 0.029	5.361GlyIle: 5.361 ± 0.053	5.271GlyLys: 5.271 ± 0.059	6.407GlyLeu: 6.407 ± 0.064	1.643GlyMet: 1.643 ± 0.033	3.631GlyAsn: 3.631 ± 0.06	1.89GlyPro: 1.89 ± 0.04	2.276GlyGln: 2.276 ± 0.043	2.537GlyArg: 2.537 ± 0.043	4.333GlySer: 4.333 ± 0.059	4.297GlyThr: 4.297 ± 0.061	4.367GlyVal: 4.367 ± 0.056	1.004GlyTrp: 1.004 ± 0.029	3.144GlyTyr: 3.144 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.261HisAla: 1.261 ± 0.028	0.172HisCys: 0.172 ± 0.012	1.042HisAsp: 1.042 ± 0.027	1.006HisGlu: 1.006 ± 0.026	1.149HisPhe: 1.149 ± 0.029	1.257HisGly: 1.257 ± 0.032	0.575HisHis: 0.575 ± 0.019	1.472HisIle: 1.472 ± 0.032	1.109HisLys: 1.109 ± 0.03	1.943HisLeu: 1.943 ± 0.039	0.386HisMet: 0.386 ± 0.018	1.018HisAsn: 1.018 ± 0.024	1.09HisPro: 1.09 ± 0.027	0.77HisGln: 0.77 ± 0.024	0.763HisArg: 0.763 ± 0.023	1.076HisSer: 1.076 ± 0.027	1.074HisThr: 1.074 ± 0.027	1.056HisVal: 1.056 ± 0.026	0.289HisTrp: 0.289 ± 0.013	0.946HisTyr: 0.946 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.381IleAla: 6.381 ± 0.067	0.714IleCys: 0.714 ± 0.021	4.454IleAsp: 4.454 ± 0.056	3.848IleGlu: 3.848 ± 0.052	3.088IlePhe: 3.088 ± 0.047	4.892IleGly: 4.892 ± 0.063	1.324IleHis: 1.324 ± 0.03	5.245IleIle: 5.245 ± 0.07	5.137IleLys: 5.137 ± 0.073	6.327IleLeu: 6.327 ± 0.075	1.356IleMet: 1.356 ± 0.033	4.408IleAsn: 4.408 ± 0.061	3.078IlePro: 3.078 ± 0.049	2.119IleGln: 2.119 ± 0.041	2.902IleArg: 2.902 ± 0.046	4.919IleSer: 4.919 ± 0.063	4.975IleThr: 4.975 ± 0.061	4.356IleVal: 4.356 ± 0.065	0.777IleTrp: 0.777 ± 0.021	2.705IleTyr: 2.705 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	5.531LysAla: 5.531 ± 0.069	0.326LysCys: 0.326 ± 0.013	4.153LysAsp: 4.153 ± 0.055	4.034LysGlu: 4.034 ± 0.055	2.676LysPhe: 2.676 ± 0.04	4.416LysGly: 4.416 ± 0.061	1.316LysHis: 1.316 ± 0.031	5.12LysIle: 5.12 ± 0.054	5.386LysLys: 5.386 ± 0.065	6.398LysLeu: 6.398 ± 0.06	1.863LysMet: 1.863 ± 0.04	4.25LysAsn: 4.25 ± 0.065	3.084LysPro: 3.084 ± 0.052	2.941LysGln: 2.941 ± 0.04	2.667LysArg: 2.667 ± 0.043	3.784LysSer: 3.784 ± 0.052	4.409LysThr: 4.409 ± 0.061	4.365LysVal: 4.365 ± 0.055	0.809LysTrp: 0.809 ± 0.027	2.891LysTyr: 2.891 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	7.205LeuAla: 7.205 ± 0.073	0.807LeuCys: 0.807 ± 0.023	4.877LeuAsp: 4.877 ± 0.053	4.426LeuGlu: 4.426 ± 0.071	4.771LeuPhe: 4.771 ± 0.074	5.793LeuGly: 5.793 ± 0.066	1.776LeuHis: 1.776 ± 0.039	6.683LeuIle: 6.683 ± 0.079	7.306LeuLys: 7.306 ± 0.081	9.482LeuLeu: 9.482 ± 0.1	2.158LeuMet: 2.158 ± 0.041	5.461LeuAsn: 5.461 ± 0.065	4.229LeuPro: 4.229 ± 0.064	3.634LeuGln: 3.634 ± 0.058	3.525LeuArg: 3.525 ± 0.051	6.669LeuSer: 6.669 ± 0.071	5.706LeuThr: 5.706 ± 0.06	5.629LeuVal: 5.629 ± 0.058	0.944LeuTrp: 0.944 ± 0.022	3.433LeuTyr: 3.433 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	1.97MetAla: 1.97 ± 0.038	0.13MetCys: 0.13 ± 0.01	1.218MetAsp: 1.218 ± 0.031	1.211MetGlu: 1.211 ± 0.029	0.829MetPhe: 0.829 ± 0.022	1.528MetGly: 1.528 ± 0.033	0.48MetHis: 0.48 ± 0.018	1.5MetIle: 1.5 ± 0.033	1.868MetLys: 1.868 ± 0.032	2.061MetLeu: 2.061 ± 0.037	0.562MetMet: 0.562 ± 0.021	1.165MetAsn: 1.165 ± 0.023	1.113MetPro: 1.113 ± 0.024	0.991MetGln: 0.991 ± 0.026	0.939MetArg: 0.939 ± 0.026	1.346MetSer: 1.346 ± 0.029	1.14MetThr: 1.14 ± 0.024	1.473MetVal: 1.473 ± 0.034	0.184MetTrp: 0.184 ± 0.011	0.667MetTyr: 0.667 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	4.16AsnAla: 4.16 ± 0.054	0.431AsnCys: 0.431 ± 0.017	2.977AsnAsp: 2.977 ± 0.053	2.679AsnGlu: 2.679 ± 0.045	2.548AsnPhe: 2.548 ± 0.051	4.107AsnGly: 4.107 ± 0.067	1.037AsnHis: 1.037 ± 0.025	4.121AsnIle: 4.121 ± 0.054	3.73AsnLys: 3.73 ± 0.054	4.979AsnLeu: 4.979 ± 0.058	1.204AsnMet: 1.204 ± 0.033	3.469AsnAsn: 3.469 ± 0.065	2.625AsnPro: 2.625 ± 0.043	2.015AsnGln: 2.015 ± 0.038	2.148AsnArg: 2.148 ± 0.041	3.19AsnSer: 3.19 ± 0.05	3.382AsnThr: 3.382 ± 0.056	3.275AsnVal: 3.275 ± 0.049	0.796AsnTrp: 0.796 ± 0.023	2.759AsnTyr: 2.759 ± 0.046	0.0AsnXaa: 0.0 ± 0.0
Pro	3.704ProAla: 3.704 ± 0.055	0.225ProCys: 0.225 ± 0.013	2.929ProAsp: 2.929 ± 0.039	2.684ProGlu: 2.684 ± 0.043	1.965ProPhe: 1.965 ± 0.033	3.151ProGly: 3.151 ± 0.052	0.766ProHis: 0.766 ± 0.022	2.369ProIle: 2.369 ± 0.04	2.413ProLys: 2.413 ± 0.041	3.47ProLeu: 3.47 ± 0.046	0.779ProMet: 0.779 ± 0.022	1.992ProAsn: 1.992 ± 0.037	1.271ProPro: 1.271 ± 0.044	1.543ProGln: 1.543 ± 0.031	1.082ProArg: 1.082 ± 0.025	2.137ProSer: 2.137 ± 0.04	2.086ProThr: 2.086 ± 0.041	3.537ProVal: 3.537 ± 0.049	0.465ProTrp: 0.465 ± 0.017	1.595ProTyr: 1.595 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	2.745GlnAla: 2.745 ± 0.046	0.197GlnCys: 0.197 ± 0.012	1.66GlnAsp: 1.66 ± 0.038	1.78GlnGlu: 1.78 ± 0.036	1.757GlnPhe: 1.757 ± 0.034	2.003GlnGly: 2.003 ± 0.04	0.829GlnHis: 0.829 ± 0.022	2.594GlnIle: 2.594 ± 0.044	2.574GlnLys: 2.574 ± 0.038	4.017GlnLeu: 4.017 ± 0.051	0.893GlnMet: 0.893 ± 0.025	1.998GlnAsn: 1.998 ± 0.041	1.61GlnPro: 1.61 ± 0.032	2.091GlnGln: 2.091 ± 0.045	1.479GlnArg: 1.479 ± 0.03	2.238GlnSer: 2.238 ± 0.036	2.227GlnThr: 2.227 ± 0.034	2.439GlnVal: 2.439 ± 0.035	0.422GlnTrp: 0.422 ± 0.017	1.565GlnTyr: 1.565 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	2.467ArgAla: 2.467 ± 0.039	0.229ArgCys: 0.229 ± 0.014	2.035ArgAsp: 2.035 ± 0.038	2.151ArgGlu: 2.151 ± 0.042	2.015ArgPhe: 2.015 ± 0.04	2.095ArgGly: 2.095 ± 0.042	0.747ArgHis: 0.747 ± 0.024	2.947ArgIle: 2.947 ± 0.04	2.678ArgLys: 2.678 ± 0.041	3.826ArgLeu: 3.826 ± 0.054	1.017ArgMet: 1.017 ± 0.025	2.012ArgAsn: 2.012 ± 0.039	1.435ArgPro: 1.435 ± 0.032	1.514ArgGln: 1.514 ± 0.039	1.584ArgArg: 1.584 ± 0.039	2.255ArgSer: 2.255 ± 0.038	1.933ArgThr: 1.933 ± 0.032	2.399ArgVal: 2.399 ± 0.037	0.473ArgTrp: 0.473 ± 0.019	1.74ArgTyr: 1.74 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	4.929SerAla: 4.929 ± 0.058	0.506SerCys: 0.506 ± 0.019	3.167SerAsp: 3.167 ± 0.049	2.627SerGlu: 2.627 ± 0.045	3.353SerPhe: 3.353 ± 0.047	4.837SerGly: 4.837 ± 0.063	1.1SerHis: 1.1 ± 0.028	4.432SerIle: 4.432 ± 0.058	3.848SerLys: 3.848 ± 0.047	5.859SerLeu: 5.859 ± 0.055	1.254SerMet: 1.254 ± 0.03	2.987SerAsn: 2.987 ± 0.06	2.532SerPro: 2.532 ± 0.04	1.97SerGln: 1.97 ± 0.039	2.258SerArg: 2.258 ± 0.037	3.634SerSer: 3.634 ± 0.057	3.501SerThr: 3.501 ± 0.056	4.235SerVal: 4.235 ± 0.054	0.716SerTrp: 0.716 ± 0.025	2.66SerTyr: 2.66 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	4.944ThrAla: 4.944 ± 0.063	0.41ThrCys: 0.41 ± 0.017	3.738ThrAsp: 3.738 ± 0.052	2.977ThrGlu: 2.977 ± 0.042	2.74ThrPhe: 2.74 ± 0.046	5.105ThrGly: 5.105 ± 0.067	1.107ThrHis: 1.107 ± 0.024	4.568ThrIle: 4.568 ± 0.061	3.263ThrLys: 3.263 ± 0.045	5.57ThrLeu: 5.57 ± 0.058	1.007ThrMet: 1.007 ± 0.026	2.972ThrAsn: 2.972 ± 0.056	2.737ThrPro: 2.737 ± 0.046	2.002ThrGln: 2.002 ± 0.039	1.964ThrArg: 1.964 ± 0.033	3.363ThrSer: 3.363 ± 0.057	3.734ThrThr: 3.734 ± 0.066	4.194ThrVal: 4.194 ± 0.053	0.728ThrTrp: 0.728 ± 0.019	2.539ThrTyr: 2.539 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	4.925ValAla: 4.925 ± 0.062	0.596ValCys: 0.596 ± 0.021	3.516ValAsp: 3.516 ± 0.047	3.197ValGlu: 3.197 ± 0.051	3.151ValPhe: 3.151 ± 0.049	3.71ValGly: 3.71 ± 0.051	1.058ValHis: 1.058 ± 0.027	5.125ValIle: 5.125 ± 0.06	4.827ValLys: 4.827 ± 0.058	6.091ValLeu: 6.091 ± 0.066	1.523ValMet: 1.523 ± 0.031	3.81ValAsn: 3.81 ± 0.048	2.525ValPro: 2.525 ± 0.044	1.973ValGln: 1.973 ± 0.034	2.251ValArg: 2.251 ± 0.039	4.316ValSer: 4.316 ± 0.057	4.094ValThr: 4.094 ± 0.063	4.33ValVal: 4.33 ± 0.066	0.682ValTrp: 0.682 ± 0.021	2.629ValTyr: 2.629 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.833TrpAla: 0.833 ± 0.028	0.123TrpCys: 0.123 ± 0.009	0.703TrpAsp: 0.703 ± 0.021	0.575TrpGlu: 0.575 ± 0.019	0.597TrpPhe: 0.597 ± 0.02	0.871TrpGly: 0.871 ± 0.026	0.309TrpHis: 0.309 ± 0.013	0.743TrpIle: 0.743 ± 0.023	0.829TrpLys: 0.829 ± 0.028	1.246TrpLeu: 1.246 ± 0.028	0.357TrpMet: 0.357 ± 0.013	0.648TrpAsn: 0.648 ± 0.021	0.41TrpPro: 0.41 ± 0.016	0.585TrpGln: 0.585 ± 0.02	0.502TrpArg: 0.502 ± 0.016	0.636TrpSer: 0.636 ± 0.021	0.616TrpThr: 0.616 ± 0.021	0.744TrpVal: 0.744 ± 0.024	0.203TrpTrp: 0.203 ± 0.011	0.492TrpTyr: 0.492 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.886TyrAla: 2.886 ± 0.046	0.403TyrCys: 0.403 ± 0.017	2.341TyrAsp: 2.341 ± 0.038	1.9TyrGlu: 1.9 ± 0.036	2.237TyrPhe: 2.237 ± 0.039	2.721TyrGly: 2.721 ± 0.051	0.951TyrHis: 0.951 ± 0.022	2.622TyrIle: 2.622 ± 0.04	2.721TyrLys: 2.721 ± 0.043	3.998TyrLeu: 3.998 ± 0.053	0.724TyrMet: 0.724 ± 0.023	2.631TyrAsn: 2.631 ± 0.045	1.811TyrPro: 1.811 ± 0.032	1.729TyrGln: 1.729 ± 0.038	1.865TyrArg: 1.865 ± 0.036	2.641TyrSer: 2.641 ± 0.046	2.651TyrThr: 2.651 ± 0.055	2.37TyrVal: 2.37 ± 0.04	0.552TyrTrp: 0.552 ± 0.018	2.007TyrTyr: 2.007 ± 0.039	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4741 proteins (1574943 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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