Amino acid dipepetide frequency for Butyrivibrio virus Arian

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.395AlaAla: 13.395 ± 2.504
0.985AlaCys: 0.985 ± 0.284
5.023AlaAsp: 5.023 ± 0.751
5.516AlaGlu: 5.516 ± 0.686
2.659AlaPhe: 2.659 ± 0.427
7.387AlaGly: 7.387 ± 1.152
1.379AlaHis: 1.379 ± 0.439
6.599AlaIle: 6.599 ± 1.374
4.531AlaLys: 4.531 ± 0.686
5.417AlaLeu: 5.417 ± 0.872
2.856AlaMet: 2.856 ± 0.479
4.432AlaAsn: 4.432 ± 0.772
2.167AlaPro: 2.167 ± 0.509
3.349AlaGln: 3.349 ± 0.785
3.644AlaArg: 3.644 ± 0.617
4.334AlaSer: 4.334 ± 0.968
5.91AlaThr: 5.91 ± 0.765
5.417AlaVal: 5.417 ± 0.998
1.083AlaTrp: 1.083 ± 0.498
3.349AlaTyr: 3.349 ± 0.57
0.0AlaXaa: 0.0 ± 0.0
Cys
0.689CysAla: 0.689 ± 0.271
0.197CysCys: 0.197 ± 0.127
1.083CysAsp: 1.083 ± 0.325
1.379CysGlu: 1.379 ± 0.369
0.295CysPhe: 0.295 ± 0.163
1.477CysGly: 1.477 ± 0.453
0.197CysHis: 0.197 ± 0.135
0.591CysIle: 0.591 ± 0.313
0.689CysLys: 0.689 ± 0.222
0.394CysLeu: 0.394 ± 0.155
0.394CysMet: 0.394 ± 0.201
0.886CysAsn: 0.886 ± 0.303
0.492CysPro: 0.492 ± 0.213
0.591CysGln: 0.591 ± 0.225
0.689CysArg: 0.689 ± 0.305
0.098CysSer: 0.098 ± 0.108
0.788CysThr: 0.788 ± 0.305
0.591CysVal: 0.591 ± 0.22
0.098CysTrp: 0.098 ± 0.084
0.492CysTyr: 0.492 ± 0.256
0.0CysXaa: 0.0 ± 0.0
Asp
6.402AspAla: 6.402 ± 1.092
0.492AspCys: 0.492 ± 0.23
4.531AspAsp: 4.531 ± 0.828
4.826AspGlu: 4.826 ± 0.779
2.167AspPhe: 2.167 ± 0.502
6.599AspGly: 6.599 ± 0.799
0.197AspHis: 0.197 ± 0.121
5.023AspIle: 5.023 ± 0.614
3.94AspLys: 3.94 ± 0.725
7.387AspLeu: 7.387 ± 1.123
1.871AspMet: 1.871 ± 0.454
3.94AspAsn: 3.94 ± 0.646
0.788AspPro: 0.788 ± 0.26
1.773AspGln: 1.773 ± 0.499
1.871AspArg: 1.871 ± 0.417
3.25AspSer: 3.25 ± 0.625
4.925AspThr: 4.925 ± 0.811
3.25AspVal: 3.25 ± 0.529
0.689AspTrp: 0.689 ± 0.226
3.349AspTyr: 3.349 ± 0.558
0.0AspXaa: 0.0 ± 0.0
Glu
4.925GluAla: 4.925 ± 0.983
0.788GluCys: 0.788 ± 0.297
2.265GluAsp: 2.265 ± 0.464
2.856GluGlu: 2.856 ± 0.604
2.659GluPhe: 2.659 ± 0.516
2.462GluGly: 2.462 ± 0.441
0.886GluHis: 0.886 ± 0.328
6.402GluIle: 6.402 ± 0.612
4.038GluLys: 4.038 ± 0.873
5.516GluLeu: 5.516 ± 1.046
1.28GluMet: 1.28 ± 0.302
5.614GluAsn: 5.614 ± 0.699
1.576GluPro: 1.576 ± 0.351
3.349GluGln: 3.349 ± 0.653
3.644GluArg: 3.644 ± 0.53
2.265GluSer: 2.265 ± 0.523
4.235GluThr: 4.235 ± 0.667
2.462GluVal: 2.462 ± 0.551
0.591GluTrp: 0.591 ± 0.276
3.25GluTyr: 3.25 ± 0.533
0.0GluXaa: 0.0 ± 0.0
Phe
1.773PheAla: 1.773 ± 0.531
0.394PheCys: 0.394 ± 0.189
4.137PheAsp: 4.137 ± 0.712
3.447PheGlu: 3.447 ± 0.574
1.871PhePhe: 1.871 ± 0.731
2.265PheGly: 2.265 ± 0.42
0.295PheHis: 0.295 ± 0.183
2.364PheIle: 2.364 ± 0.501
2.955PheLys: 2.955 ± 0.58
1.871PheLeu: 1.871 ± 0.465
1.477PheMet: 1.477 ± 0.333
2.659PheAsn: 2.659 ± 0.57
0.788PhePro: 0.788 ± 0.276
0.788PheGln: 0.788 ± 0.261
1.576PheArg: 1.576 ± 0.352
2.856PheSer: 2.856 ± 0.849
2.561PheThr: 2.561 ± 0.605
1.773PheVal: 1.773 ± 0.371
0.591PheTrp: 0.591 ± 0.221
2.758PheTyr: 2.758 ± 0.55
0.0PheXaa: 0.0 ± 0.0
Gly
6.993GlyAla: 6.993 ± 1.114
0.394GlyCys: 0.394 ± 0.162
4.531GlyAsp: 4.531 ± 0.742
4.531GlyGlu: 4.531 ± 0.648
2.955GlyPhe: 2.955 ± 0.557
4.925GlyGly: 4.925 ± 0.75
0.788GlyHis: 0.788 ± 0.325
4.432GlyIle: 4.432 ± 0.782
5.417GlyLys: 5.417 ± 0.925
4.334GlyLeu: 4.334 ± 0.929
1.182GlyMet: 1.182 ± 0.271
3.644GlyAsn: 3.644 ± 0.571
0.098GlyPro: 0.098 ± 0.104
1.97GlyGln: 1.97 ± 0.397
3.053GlyArg: 3.053 ± 0.516
2.462GlySer: 2.462 ± 0.589
6.008GlyThr: 6.008 ± 1.096
6.008GlyVal: 6.008 ± 0.775
0.886GlyTrp: 0.886 ± 0.33
2.659GlyTyr: 2.659 ± 0.626
0.0GlyXaa: 0.0 ± 0.0
His
0.689HisAla: 0.689 ± 0.291
0.394HisCys: 0.394 ± 0.185
1.379HisAsp: 1.379 ± 0.355
0.295HisGlu: 0.295 ± 0.173
0.492HisPhe: 0.492 ± 0.184
1.477HisGly: 1.477 ± 0.371
0.295HisHis: 0.295 ± 0.169
0.788HisIle: 0.788 ± 0.317
0.985HisLys: 0.985 ± 0.307
1.083HisLeu: 1.083 ± 0.331
0.197HisMet: 0.197 ± 0.139
1.083HisAsn: 1.083 ± 0.322
0.492HisPro: 0.492 ± 0.21
0.394HisGln: 0.394 ± 0.215
0.394HisArg: 0.394 ± 0.212
0.591HisSer: 0.591 ± 0.287
0.591HisThr: 0.591 ± 0.239
1.182HisVal: 1.182 ± 0.549
0.197HisTrp: 0.197 ± 0.139
0.985HisTyr: 0.985 ± 0.311
0.0HisXaa: 0.0 ± 0.0
Ile
5.811IleAla: 5.811 ± 0.664
0.591IleCys: 0.591 ± 0.246
6.402IleAsp: 6.402 ± 0.855
5.417IleGlu: 5.417 ± 1.07
2.561IlePhe: 2.561 ± 0.474
3.743IleGly: 3.743 ± 0.551
0.886IleHis: 0.886 ± 0.273
6.402IleIle: 6.402 ± 0.872
6.895IleLys: 6.895 ± 1.036
4.826IleLeu: 4.826 ± 0.68
1.871IleMet: 1.871 ± 0.38
4.235IleAsn: 4.235 ± 0.69
2.561IlePro: 2.561 ± 0.45
1.379IleGln: 1.379 ± 0.361
2.856IleArg: 2.856 ± 0.562
3.25IleSer: 3.25 ± 0.492
5.713IleThr: 5.713 ± 0.756
4.235IleVal: 4.235 ± 0.637
1.674IleTrp: 1.674 ± 0.49
2.758IleTyr: 2.758 ± 0.54
0.0IleXaa: 0.0 ± 0.0
Lys
6.304LysAla: 6.304 ± 1.037
0.689LysCys: 0.689 ± 0.305
4.235LysAsp: 4.235 ± 0.732
3.841LysGlu: 3.841 ± 0.723
2.167LysPhe: 2.167 ± 0.486
2.955LysGly: 2.955 ± 0.716
1.674LysHis: 1.674 ± 0.497
5.713LysIle: 5.713 ± 0.773
5.22LysLys: 5.22 ± 0.673
5.91LysLeu: 5.91 ± 0.818
1.871LysMet: 1.871 ± 0.464
4.235LysAsn: 4.235 ± 0.554
2.758LysPro: 2.758 ± 0.557
2.561LysGln: 2.561 ± 0.47
3.546LysArg: 3.546 ± 0.712
4.137LysSer: 4.137 ± 0.591
4.728LysThr: 4.728 ± 0.655
3.152LysVal: 3.152 ± 0.545
1.182LysTrp: 1.182 ± 0.357
3.25LysTyr: 3.25 ± 0.664
0.0LysXaa: 0.0 ± 0.0
Leu
5.319LeuAla: 5.319 ± 0.731
0.985LeuCys: 0.985 ± 0.304
4.038LeuAsp: 4.038 ± 1.076
4.235LeuGlu: 4.235 ± 0.603
2.068LeuPhe: 2.068 ± 0.388
2.167LeuGly: 2.167 ± 0.444
1.182LeuHis: 1.182 ± 0.475
4.531LeuIle: 4.531 ± 0.68
6.304LeuLys: 6.304 ± 0.788
4.728LeuLeu: 4.728 ± 0.888
1.379LeuMet: 1.379 ± 0.405
6.599LeuAsn: 6.599 ± 0.756
1.97LeuPro: 1.97 ± 0.392
4.334LeuGln: 4.334 ± 0.6
2.265LeuArg: 2.265 ± 0.453
4.925LeuSer: 4.925 ± 1.06
6.599LeuThr: 6.599 ± 1.088
1.97LeuVal: 1.97 ± 0.45
0.689LeuTrp: 0.689 ± 0.303
2.462LeuTyr: 2.462 ± 0.459
0.0LeuXaa: 0.0 ± 0.0
Met
1.97MetAla: 1.97 ± 0.397
0.295MetCys: 0.295 ± 0.202
1.28MetAsp: 1.28 ± 0.358
1.674MetGlu: 1.674 ± 0.336
2.462MetPhe: 2.462 ± 1.178
1.28MetGly: 1.28 ± 0.335
0.492MetHis: 0.492 ± 0.199
1.871MetIle: 1.871 ± 0.418
3.152MetLys: 3.152 ± 0.613
0.788MetLeu: 0.788 ± 0.35
0.788MetMet: 0.788 ± 0.243
1.379MetAsn: 1.379 ± 0.331
0.591MetPro: 0.591 ± 0.199
1.871MetGln: 1.871 ± 0.423
0.591MetArg: 0.591 ± 0.215
2.364MetSer: 2.364 ± 0.456
1.97MetThr: 1.97 ± 0.582
0.591MetVal: 0.591 ± 0.256
0.197MetTrp: 0.197 ± 0.14
0.689MetTyr: 0.689 ± 0.315
0.0MetXaa: 0.0 ± 0.0
Asn
5.713AsnAla: 5.713 ± 0.746
1.477AsnCys: 1.477 ± 0.524
4.629AsnAsp: 4.629 ± 0.826
2.955AsnGlu: 2.955 ± 0.733
1.871AsnPhe: 1.871 ± 0.446
5.614AsnGly: 5.614 ± 0.874
0.788AsnHis: 0.788 ± 0.444
5.713AsnIle: 5.713 ± 0.699
3.94AsnLys: 3.94 ± 0.805
4.235AsnLeu: 4.235 ± 0.624
2.659AsnMet: 2.659 ± 0.891
4.925AsnAsn: 4.925 ± 0.71
2.068AsnPro: 2.068 ± 0.417
0.689AsnGln: 0.689 ± 0.239
2.068AsnArg: 2.068 ± 0.493
2.659AsnSer: 2.659 ± 0.685
5.417AsnThr: 5.417 ± 0.579
5.713AsnVal: 5.713 ± 0.809
0.788AsnTrp: 0.788 ± 0.255
2.659AsnTyr: 2.659 ± 0.613
0.0AsnXaa: 0.0 ± 0.0
Pro
1.871ProAla: 1.871 ± 0.474
0.689ProCys: 0.689 ± 0.261
2.167ProAsp: 2.167 ± 0.485
1.182ProGlu: 1.182 ± 0.411
1.477ProPhe: 1.477 ± 0.35
0.689ProGly: 0.689 ± 0.32
0.492ProHis: 0.492 ± 0.22
1.871ProIle: 1.871 ± 0.398
1.674ProLys: 1.674 ± 0.421
1.674ProLeu: 1.674 ± 0.287
0.295ProMet: 0.295 ± 0.153
0.886ProAsn: 0.886 ± 0.286
0.591ProPro: 0.591 ± 0.213
1.182ProGln: 1.182 ± 0.346
1.674ProArg: 1.674 ± 0.538
1.379ProSer: 1.379 ± 0.408
2.167ProThr: 2.167 ± 0.493
1.97ProVal: 1.97 ± 0.446
0.492ProTrp: 0.492 ± 0.234
1.083ProTyr: 1.083 ± 0.285
0.0ProXaa: 0.0 ± 0.0
Gln
3.349GlnAla: 3.349 ± 0.917
0.197GlnCys: 0.197 ± 0.137
2.955GlnAsp: 2.955 ± 0.624
2.561GlnGlu: 2.561 ± 0.451
0.788GlnPhe: 0.788 ± 0.287
1.97GlnGly: 1.97 ± 0.467
0.098GlnHis: 0.098 ± 0.103
3.152GlnIle: 3.152 ± 0.678
2.955GlnLys: 2.955 ± 0.634
1.871GlnLeu: 1.871 ± 0.377
0.886GlnMet: 0.886 ± 0.282
2.659GlnAsn: 2.659 ± 0.594
0.689GlnPro: 0.689 ± 0.294
2.561GlnGln: 2.561 ± 0.513
1.97GlnArg: 1.97 ± 0.493
2.364GlnSer: 2.364 ± 0.502
2.758GlnThr: 2.758 ± 0.511
1.674GlnVal: 1.674 ± 0.394
0.098GlnTrp: 0.098 ± 0.096
1.083GlnTyr: 1.083 ± 0.29
0.0GlnXaa: 0.0 ± 0.0
Arg
3.053ArgAla: 3.053 ± 0.393
0.689ArgCys: 0.689 ± 0.271
2.561ArgAsp: 2.561 ± 0.762
2.462ArgGlu: 2.462 ± 0.394
2.167ArgPhe: 2.167 ± 0.389
3.94ArgGly: 3.94 ± 0.6
0.394ArgHis: 0.394 ± 0.184
2.659ArgIle: 2.659 ± 0.495
2.758ArgLys: 2.758 ± 0.517
2.856ArgLeu: 2.856 ± 0.484
1.083ArgMet: 1.083 ± 0.28
2.561ArgAsn: 2.561 ± 0.432
0.886ArgPro: 0.886 ± 0.295
2.167ArgGln: 2.167 ± 0.56
2.462ArgArg: 2.462 ± 0.62
2.462ArgSer: 2.462 ± 0.522
2.364ArgThr: 2.364 ± 0.593
3.152ArgVal: 3.152 ± 0.503
0.295ArgTrp: 0.295 ± 0.157
1.182ArgTyr: 1.182 ± 0.283
0.0ArgXaa: 0.0 ± 0.0
Ser
4.432SerAla: 4.432 ± 0.89
0.295SerCys: 0.295 ± 0.16
4.334SerAsp: 4.334 ± 0.607
3.644SerGlu: 3.644 ± 0.472
2.462SerPhe: 2.462 ± 0.76
5.417SerGly: 5.417 ± 0.783
0.886SerHis: 0.886 ± 0.276
3.743SerIle: 3.743 ± 0.646
3.447SerLys: 3.447 ± 0.69
4.235SerLeu: 4.235 ± 1.071
1.576SerMet: 1.576 ± 0.473
3.644SerAsn: 3.644 ± 0.889
1.083SerPro: 1.083 ± 0.415
1.674SerGln: 1.674 ± 0.378
2.167SerArg: 2.167 ± 0.447
2.758SerSer: 2.758 ± 0.695
2.955SerThr: 2.955 ± 0.613
3.644SerVal: 3.644 ± 0.771
0.492SerTrp: 0.492 ± 0.231
1.28SerTyr: 1.28 ± 0.446
0.0SerXaa: 0.0 ± 0.0
Thr
8.076ThrAla: 8.076 ± 0.815
0.394ThrCys: 0.394 ± 0.192
4.925ThrAsp: 4.925 ± 0.76
4.235ThrGlu: 4.235 ± 0.514
3.546ThrPhe: 3.546 ± 0.542
6.107ThrGly: 6.107 ± 0.873
1.182ThrHis: 1.182 ± 0.329
3.349ThrIle: 3.349 ± 0.531
3.349ThrLys: 3.349 ± 0.491
4.531ThrLeu: 4.531 ± 0.656
1.576ThrMet: 1.576 ± 0.419
4.432ThrAsn: 4.432 ± 0.766
3.25ThrPro: 3.25 ± 0.645
2.955ThrGln: 2.955 ± 0.626
3.25ThrArg: 3.25 ± 0.527
4.728ThrSer: 4.728 ± 1.604
4.629ThrThr: 4.629 ± 0.651
6.599ThrVal: 6.599 ± 0.91
0.591ThrTrp: 0.591 ± 0.212
2.364ThrTyr: 2.364 ± 0.465
0.0ThrXaa: 0.0 ± 0.0
Val
4.925ValAla: 4.925 ± 0.862
0.689ValCys: 0.689 ± 0.261
3.644ValAsp: 3.644 ± 0.735
2.364ValGlu: 2.364 ± 0.471
1.674ValPhe: 1.674 ± 0.405
2.462ValGly: 2.462 ± 0.582
0.886ValHis: 0.886 ± 0.371
3.94ValIle: 3.94 ± 0.676
4.925ValLys: 4.925 ± 0.629
3.94ValLeu: 3.94 ± 0.699
1.871ValMet: 1.871 ± 0.449
4.826ValAsn: 4.826 ± 0.783
1.773ValPro: 1.773 ± 0.362
1.674ValGln: 1.674 ± 0.466
2.167ValArg: 2.167 ± 0.535
4.629ValSer: 4.629 ± 0.747
5.22ValThr: 5.22 ± 1.157
2.659ValVal: 2.659 ± 0.528
0.492ValTrp: 0.492 ± 0.178
3.349ValTyr: 3.349 ± 0.464
0.0ValXaa: 0.0 ± 0.0
Trp
0.788TrpAla: 0.788 ± 0.27
0.098TrpCys: 0.098 ± 0.092
1.28TrpAsp: 1.28 ± 0.405
0.985TrpGlu: 0.985 ± 0.359
0.886TrpPhe: 0.886 ± 0.33
0.886TrpGly: 0.886 ± 0.373
0.197TrpHis: 0.197 ± 0.152
0.985TrpIle: 0.985 ± 0.323
0.591TrpLys: 0.591 ± 0.228
0.788TrpLeu: 0.788 ± 0.367
0.0TrpMet: 0.0 ± 0.0
0.985TrpAsn: 0.985 ± 0.296
0.0TrpPro: 0.0 ± 0.0
0.689TrpGln: 0.689 ± 0.241
0.591TrpArg: 0.591 ± 0.217
0.591TrpSer: 0.591 ± 0.305
0.689TrpThr: 0.689 ± 0.262
0.591TrpVal: 0.591 ± 0.216
0.0TrpTrp: 0.0 ± 0.0
0.098TrpTyr: 0.098 ± 0.11
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.053TyrAla: 3.053 ± 0.587
1.379TyrCys: 1.379 ± 0.535
1.871TyrAsp: 1.871 ± 0.373
2.659TyrGlu: 2.659 ± 0.513
1.97TyrPhe: 1.97 ± 0.473
3.447TyrGly: 3.447 ± 0.61
0.788TyrHis: 0.788 ± 0.317
3.94TyrIle: 3.94 ± 0.745
2.364TyrLys: 2.364 ± 0.526
2.364TyrLeu: 2.364 ± 0.402
1.083TyrMet: 1.083 ± 0.393
2.955TyrAsn: 2.955 ± 0.686
0.886TyrPro: 0.886 ± 0.437
0.689TyrGln: 0.689 ± 0.296
1.674TyrArg: 1.674 ± 0.409
2.068TyrSer: 2.068 ± 0.438
3.841TyrThr: 3.841 ± 0.608
1.477TyrVal: 1.477 ± 0.469
0.591TyrTrp: 0.591 ± 0.225
2.364TyrTyr: 2.364 ± 0.485
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 54 proteins (10154 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski