Amino acid dipepetide frequency for Blastochloris viridis (Rhodopseudomonas viridis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.089AlaAla: 23.089 ± 0.246	1.138AlaCys: 1.138 ± 0.036	7.744AlaAsp: 7.744 ± 0.09	8.862AlaGlu: 8.862 ± 0.118	4.827AlaPhe: 4.827 ± 0.077	12.256AlaGly: 12.256 ± 0.131	2.333AlaHis: 2.333 ± 0.056	6.435AlaIle: 6.435 ± 0.086	4.24AlaLys: 4.24 ± 0.088	14.991AlaLeu: 14.991 ± 0.163	3.331AlaMet: 3.331 ± 0.066	2.815AlaAsn: 2.815 ± 0.061	6.619AlaPro: 6.619 ± 0.105	3.587AlaGln: 3.587 ± 0.065	10.523AlaArg: 10.523 ± 0.119	6.487AlaSer: 6.487 ± 0.098	7.14AlaThr: 7.14 ± 0.102	11.191AlaVal: 11.191 ± 0.128	1.595AlaTrp: 1.595 ± 0.043	2.361AlaTyr: 2.361 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.934CysAla: 0.934 ± 0.037	0.111CysCys: 0.111 ± 0.011	0.522CysAsp: 0.522 ± 0.025	0.47CysGlu: 0.47 ± 0.022	0.271CysPhe: 0.271 ± 0.016	0.917CysGly: 0.917 ± 0.028	0.243CysHis: 0.243 ± 0.019	0.344CysIle: 0.344 ± 0.019	0.156CysLys: 0.156 ± 0.013	0.769CysLeu: 0.769 ± 0.028	0.133CysMet: 0.133 ± 0.011	0.185CysAsn: 0.185 ± 0.016	0.491CysPro: 0.491 ± 0.024	0.199CysGln: 0.199 ± 0.014	0.73CysArg: 0.73 ± 0.028	0.451CysSer: 0.451 ± 0.022	0.381CysThr: 0.381 ± 0.022	0.58CysVal: 0.58 ± 0.023	0.104CysTrp: 0.104 ± 0.011	0.189CysTyr: 0.189 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.574AspAla: 7.574 ± 0.097	0.476AspCys: 0.476 ± 0.023	3.394AspAsp: 3.394 ± 0.075	3.17AspGlu: 3.17 ± 0.073	1.913AspPhe: 1.913 ± 0.049	5.322AspGly: 5.322 ± 0.09	1.212AspHis: 1.212 ± 0.033	2.936AspIle: 2.936 ± 0.061	1.564AspLys: 1.564 ± 0.052	6.172AspLeu: 6.172 ± 0.084	1.043AspMet: 1.043 ± 0.028	1.117AspAsn: 1.117 ± 0.032	3.612AspPro: 3.612 ± 0.053	1.565AspGln: 1.565 ± 0.036	4.608AspArg: 4.608 ± 0.084	2.107AspSer: 2.107 ± 0.045	2.747AspThr: 2.747 ± 0.05	4.399AspVal: 4.399 ± 0.068	0.838AspTrp: 0.838 ± 0.03	1.325AspTyr: 1.325 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	8.114GluAla: 8.114 ± 0.12	0.325GluCys: 0.325 ± 0.021	2.564GluAsp: 2.564 ± 0.059	2.488GluGlu: 2.488 ± 0.064	1.722GluPhe: 1.722 ± 0.045	3.732GluGly: 3.732 ± 0.071	1.019GluHis: 1.019 ± 0.033	3.135GluIle: 3.135 ± 0.063	1.662GluLys: 1.662 ± 0.044	5.473GluLeu: 5.473 ± 0.093	1.303GluMet: 1.303 ± 0.033	1.114GluAsn: 1.114 ± 0.031	3.165GluPro: 3.165 ± 0.075	1.903GluGln: 1.903 ± 0.05	5.447GluArg: 5.447 ± 0.097	2.153GluSer: 2.153 ± 0.045	3.223GluThr: 3.223 ± 0.058	4.454GluVal: 4.454 ± 0.073	0.591GluTrp: 0.591 ± 0.025	0.787GluTyr: 0.787 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	5.136PheAla: 5.136 ± 0.076	0.364PheCys: 0.364 ± 0.02	2.676PheAsp: 2.676 ± 0.065	2.205PheGlu: 2.205 ± 0.042	1.253PhePhe: 1.253 ± 0.036	3.763PheGly: 3.763 ± 0.061	0.664PheHis: 0.664 ± 0.026	1.392PheIle: 1.392 ± 0.04	0.979PheLys: 0.979 ± 0.038	3.144PheLeu: 3.144 ± 0.064	0.608PheMet: 0.608 ± 0.024	0.894PheAsn: 0.894 ± 0.031	1.534PhePro: 1.534 ± 0.041	0.923PheGln: 0.923 ± 0.032	2.444PheArg: 2.444 ± 0.053	1.784PheSer: 1.784 ± 0.046	1.822PheThr: 1.822 ± 0.046	2.995PheVal: 2.995 ± 0.06	0.451PheTrp: 0.451 ± 0.024	0.759PheTyr: 0.759 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	10.28GlyAla: 10.28 ± 0.131	0.913GlyCys: 0.913 ± 0.031	4.402GlyAsp: 4.402 ± 0.085	4.734GlyGlu: 4.734 ± 0.083	3.595GlyPhe: 3.595 ± 0.057	7.539GlyGly: 7.539 ± 0.131	1.893GlyHis: 1.893 ± 0.048	4.063GlyIle: 4.063 ± 0.069	2.74GlyLys: 2.74 ± 0.067	8.928GlyLeu: 8.928 ± 0.109	1.915GlyMet: 1.915 ± 0.044	1.823GlyAsn: 1.823 ± 0.052	3.923GlyPro: 3.923 ± 0.067	2.514GlyGln: 2.514 ± 0.052	7.218GlyArg: 7.218 ± 0.101	4.446GlySer: 4.446 ± 0.103	4.816GlyThr: 4.816 ± 0.118	6.51GlyVal: 6.51 ± 0.083	1.368GlyTrp: 1.368 ± 0.039	2.116GlyTyr: 2.116 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.469HisAla: 2.469 ± 0.051	0.203HisCys: 0.203 ± 0.016	1.265HisAsp: 1.265 ± 0.034	0.858HisGlu: 0.858 ± 0.03	0.745HisPhe: 0.745 ± 0.027	1.973HisGly: 1.973 ± 0.051	0.567HisHis: 0.567 ± 0.028	0.817HisIle: 0.817 ± 0.026	0.4HisLys: 0.4 ± 0.023	1.97HisLeu: 1.97 ± 0.046	0.403HisMet: 0.403 ± 0.02	0.361HisAsn: 0.361 ± 0.021	1.307HisPro: 1.307 ± 0.037	0.495HisGln: 0.495 ± 0.023	1.63HisArg: 1.63 ± 0.046	0.772HisSer: 0.772 ± 0.032	0.766HisThr: 0.766 ± 0.03	1.487HisVal: 1.487 ± 0.039	0.315HisTrp: 0.315 ± 0.016	0.479HisTyr: 0.479 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	7.595IleAla: 7.595 ± 0.088	0.416IleCys: 0.416 ± 0.02	3.484IleAsp: 3.484 ± 0.06	3.458IleGlu: 3.458 ± 0.057	1.24IlePhe: 1.24 ± 0.035	4.701IleGly: 4.701 ± 0.079	0.795IleHis: 0.795 ± 0.032	1.706IleIle: 1.706 ± 0.048	1.351IleLys: 1.351 ± 0.044	3.756IleLeu: 3.756 ± 0.076	0.699IleMet: 0.699 ± 0.028	1.15IleAsn: 1.15 ± 0.036	2.055IlePro: 2.055 ± 0.047	1.054IleGln: 1.054 ± 0.04	3.088IleArg: 3.088 ± 0.059	2.221IleSer: 2.221 ± 0.05	2.394IleThr: 2.394 ± 0.058	4.175IleVal: 4.175 ± 0.089	0.447IleTrp: 0.447 ± 0.022	0.967IleTyr: 0.967 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	4.021LysAla: 4.021 ± 0.081	0.129LysCys: 0.129 ± 0.012	1.509LysAsp: 1.509 ± 0.046	1.277LysGlu: 1.277 ± 0.037	0.748LysPhe: 0.748 ± 0.027	2.162LysGly: 2.162 ± 0.055	0.479LysHis: 0.479 ± 0.023	1.441LysIle: 1.441 ± 0.043	1.011LysLys: 1.011 ± 0.042	3.085LysLeu: 3.085 ± 0.064	0.605LysMet: 0.605 ± 0.029	0.66LysAsn: 0.66 ± 0.027	2.037LysPro: 2.037 ± 0.053	0.779LysGln: 0.779 ± 0.03	2.265LysArg: 2.265 ± 0.053	1.533LysSer: 1.533 ± 0.041	1.871LysThr: 1.871 ± 0.061	2.513LysVal: 2.513 ± 0.05	0.278LysTrp: 0.278 ± 0.017	0.495LysTyr: 0.495 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	16.273LeuAla: 16.273 ± 0.178	0.763LeuCys: 0.763 ± 0.027	6.582LeuAsp: 6.582 ± 0.098	4.981LeuGlu: 4.981 ± 0.076	3.494LeuPhe: 3.494 ± 0.062	8.667LeuGly: 8.667 ± 0.1	1.786LeuHis: 1.786 ± 0.044	4.77LeuIle: 4.77 ± 0.078	3.582LeuLys: 3.582 ± 0.062	8.947LeuLeu: 8.947 ± 0.123	2.046LeuMet: 2.046 ± 0.049	2.108LeuAsn: 2.108 ± 0.043	5.746LeuPro: 5.746 ± 0.095	2.406LeuGln: 2.406 ± 0.046	6.934LeuArg: 6.934 ± 0.107	5.581LeuSer: 5.581 ± 0.072	5.579LeuThr: 5.579 ± 0.093	8.513LeuVal: 8.513 ± 0.102	1.115LeuTrp: 1.115 ± 0.033	1.918LeuTyr: 1.918 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	2.936MetAla: 2.936 ± 0.061	0.148MetCys: 0.148 ± 0.012	0.804MetAsp: 0.804 ± 0.031	0.797MetGlu: 0.797 ± 0.03	0.671MetPhe: 0.671 ± 0.027	1.281MetGly: 1.281 ± 0.044	0.319MetHis: 0.319 ± 0.017	1.037MetIle: 1.037 ± 0.037	0.665MetLys: 0.665 ± 0.027	2.244MetLeu: 2.244 ± 0.05	0.605MetMet: 0.605 ± 0.027	0.557MetAsn: 0.557 ± 0.022	1.383MetPro: 1.383 ± 0.038	0.617MetGln: 0.617 ± 0.024	1.717MetArg: 1.717 ± 0.041	1.372MetSer: 1.372 ± 0.035	1.634MetThr: 1.634 ± 0.038	1.863MetVal: 1.863 ± 0.049	0.212MetTrp: 0.212 ± 0.015	0.232MetTyr: 0.232 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.887AsnAla: 2.887 ± 0.066	0.208AsnCys: 0.208 ± 0.017	1.171AsnAsp: 1.171 ± 0.037	0.992AsnGlu: 0.992 ± 0.034	0.776AsnPhe: 0.776 ± 0.03	2.021AsnGly: 2.021 ± 0.059	0.4AsnHis: 0.4 ± 0.02	1.047AsnIle: 1.047 ± 0.036	0.555AsnLys: 0.555 ± 0.023	2.285AsnLeu: 2.285 ± 0.048	0.455AsnMet: 0.455 ± 0.022	0.534AsnAsn: 0.534 ± 0.028	1.628AsnPro: 1.628 ± 0.042	0.591AsnGln: 0.591 ± 0.026	1.665AsnArg: 1.665 ± 0.041	0.937AsnSer: 0.937 ± 0.034	1.071AsnThr: 1.071 ± 0.042	1.779AsnVal: 1.779 ± 0.046	0.342AsnTrp: 0.342 ± 0.019	0.478AsnTyr: 0.478 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	8.308ProAla: 8.308 ± 0.123	0.377ProCys: 0.377 ± 0.022	3.857ProAsp: 3.857 ± 0.067	3.315ProGlu: 3.315 ± 0.068	2.045ProPhe: 2.045 ± 0.055	4.956ProGly: 4.956 ± 0.075	1.032ProHis: 1.032 ± 0.035	2.241ProIle: 2.241 ± 0.047	1.595ProLys: 1.595 ± 0.044	5.025ProLeu: 5.025 ± 0.076	1.11ProMet: 1.11 ± 0.031	1.272ProAsn: 1.272 ± 0.039	3.568ProPro: 3.568 ± 0.087	1.548ProGln: 1.548 ± 0.042	3.59ProArg: 3.59 ± 0.086	2.759ProSer: 2.759 ± 0.056	2.773ProThr: 2.773 ± 0.051	4.536ProVal: 4.536 ± 0.07	0.686ProTrp: 0.686 ± 0.025	1.017ProTyr: 1.017 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.675GlnAla: 3.675 ± 0.065	0.169GlnCys: 0.169 ± 0.015	1.314GlnAsp: 1.314 ± 0.038	1.129GlnGlu: 1.129 ± 0.037	0.953GlnPhe: 0.953 ± 0.033	1.906GlnGly: 1.906 ± 0.043	0.573GlnHis: 0.573 ± 0.024	1.594GlnIle: 1.594 ± 0.044	0.741GlnLys: 0.741 ± 0.028	2.8GlnLeu: 2.8 ± 0.058	0.681GlnMet: 0.681 ± 0.027	0.632GlnAsn: 0.632 ± 0.028	1.793GlnPro: 1.793 ± 0.046	1.019GlnGln: 1.019 ± 0.033	2.446GlnArg: 2.446 ± 0.056	1.415GlnSer: 1.415 ± 0.039	1.613GlnThr: 1.613 ± 0.047	2.222GlnVal: 2.222 ± 0.046	0.303GlnTrp: 0.303 ± 0.016	0.494GlnTyr: 0.494 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	9.623ArgAla: 9.623 ± 0.13	0.545ArgCys: 0.545 ± 0.027	4.247ArgAsp: 4.247 ± 0.071	4.215ArgGlu: 4.215 ± 0.075	3.254ArgPhe: 3.254 ± 0.056	5.58ArgGly: 5.58 ± 0.086	1.886ArgHis: 1.886 ± 0.052	3.926ArgIle: 3.926 ± 0.061	1.981ArgLys: 1.981 ± 0.056	9.389ArgLeu: 9.389 ± 0.126	1.78ArgMet: 1.78 ± 0.037	1.639ArgAsn: 1.639 ± 0.04	4.456ArgPro: 4.456 ± 0.102	2.446ArgGln: 2.446 ± 0.051	7.096ArgArg: 7.096 ± 0.109	3.588ArgSer: 3.588 ± 0.064	3.907ArgThr: 3.907 ± 0.072	5.433ArgVal: 5.433 ± 0.083	1.076ArgTrp: 1.076 ± 0.03	1.654ArgTyr: 1.654 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.195SerAla: 6.195 ± 0.092	0.39SerCys: 0.39 ± 0.021	2.595SerAsp: 2.595 ± 0.055	2.467SerGlu: 2.467 ± 0.052	2.002SerPhe: 2.002 ± 0.049	5.173SerGly: 5.173 ± 0.12	1.01SerHis: 1.01 ± 0.032	2.257SerIle: 2.257 ± 0.062	1.253SerLys: 1.253 ± 0.042	4.778SerLeu: 4.778 ± 0.079	1.011SerMet: 1.011 ± 0.03	1.152SerAsn: 1.152 ± 0.044	2.695SerPro: 2.695 ± 0.049	1.401SerGln: 1.401 ± 0.04	3.674SerArg: 3.674 ± 0.07	2.758SerSer: 2.758 ± 0.083	2.66SerThr: 2.66 ± 0.061	3.718SerVal: 3.718 ± 0.07	0.677SerTrp: 0.677 ± 0.026	1.169SerTyr: 1.169 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	7.332ThrAla: 7.332 ± 0.103	0.44ThrCys: 0.44 ± 0.02	2.776ThrAsp: 2.776 ± 0.05	2.61ThrGlu: 2.61 ± 0.053	2.02ThrPhe: 2.02 ± 0.042	4.843ThrGly: 4.843 ± 0.087	0.959ThrHis: 0.959 ± 0.031	2.609ThrIle: 2.609 ± 0.063	1.466ThrLys: 1.466 ± 0.047	6.068ThrLeu: 6.068 ± 0.098	0.972ThrMet: 0.972 ± 0.029	1.15ThrAsn: 1.15 ± 0.04	3.392ThrPro: 3.392 ± 0.069	1.288ThrGln: 1.288 ± 0.041	3.58ThrArg: 3.58 ± 0.058	2.698ThrSer: 2.698 ± 0.067	3.057ThrThr: 3.057 ± 0.098	5.071ThrVal: 5.071 ± 0.106	0.619ThrTrp: 0.619 ± 0.028	1.04ThrTyr: 1.04 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	11.559ValAla: 11.559 ± 0.114	0.694ValCys: 0.694 ± 0.029	4.327ValAsp: 4.327 ± 0.068	4.989ValGlu: 4.989 ± 0.071	2.991ValPhe: 2.991 ± 0.071	6.162ValGly: 6.162 ± 0.081	1.406ValHis: 1.406 ± 0.036	3.701ValIle: 3.701 ± 0.06	2.155ValLys: 2.155 ± 0.048	8.351ValLeu: 8.351 ± 0.115	1.747ValMet: 1.747 ± 0.052	1.831ValAsn: 1.831 ± 0.049	4.535ValPro: 4.535 ± 0.081	1.995ValGln: 1.995 ± 0.044	6.0ValArg: 6.0 ± 0.077	4.249ValSer: 4.249 ± 0.068	4.812ValThr: 4.812 ± 0.1	7.773ValVal: 7.773 ± 0.101	0.917ValTrp: 0.917 ± 0.032	1.439ValTyr: 1.439 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.175TrpAla: 1.175 ± 0.042	0.139TrpCys: 0.139 ± 0.012	0.558TrpAsp: 0.558 ± 0.026	0.453TrpGlu: 0.453 ± 0.024	0.484TrpPhe: 0.484 ± 0.021	0.848TrpGly: 0.848 ± 0.032	0.292TrpHis: 0.292 ± 0.019	0.574TrpIle: 0.574 ± 0.023	0.318TrpLys: 0.318 ± 0.017	1.614TrpLeu: 1.614 ± 0.042	0.303TrpMet: 0.303 ± 0.018	0.313TrpAsn: 0.313 ± 0.016	0.72TrpPro: 0.72 ± 0.023	0.522TrpGln: 0.522 ± 0.026	1.298TrpArg: 1.298 ± 0.035	0.771TrpSer: 0.771 ± 0.026	0.77TrpThr: 0.77 ± 0.029	0.841TrpVal: 0.841 ± 0.029	0.235TrpTrp: 0.235 ± 0.016	0.233TrpTyr: 0.233 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.389TyrAla: 2.389 ± 0.047	0.229TyrCys: 0.229 ± 0.015	1.3TyrAsp: 1.3 ± 0.042	0.904TyrGlu: 0.904 ± 0.036	0.787TyrPhe: 0.787 ± 0.028	1.933TyrGly: 1.933 ± 0.048	0.417TyrHis: 0.417 ± 0.019	0.727TyrIle: 0.727 ± 0.028	0.485TyrLys: 0.485 ± 0.025	1.999TyrLeu: 1.999 ± 0.043	0.344TyrMet: 0.344 ± 0.019	0.512TyrAsn: 0.512 ± 0.026	0.951TyrPro: 0.951 ± 0.034	0.622TyrGln: 0.622 ± 0.025	1.767TyrArg: 1.767 ± 0.042	0.953TyrSer: 0.953 ± 0.031	0.954TyrThr: 0.954 ± 0.045	1.582TyrVal: 1.582 ± 0.043	0.294TyrTrp: 0.294 ± 0.018	0.551TyrTyr: 0.551 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3241 proteins (1038761 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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