Amino acid dipepetide frequency for Alces alces faeces associated microvirus MP11 5517

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.772AlaAla: 0.772 ± 0.514
1.544AlaCys: 1.544 ± 1.406
3.089AlaAsp: 3.089 ± 1.728
1.544AlaGlu: 1.544 ± 0.925
1.544AlaPhe: 1.544 ± 1.028
2.317AlaGly: 2.317 ± 1.398
3.089AlaHis: 3.089 ± 1.155
3.861AlaIle: 3.861 ± 1.798
3.861AlaLys: 3.861 ± 2.65
3.089AlaLeu: 3.089 ± 1.265
1.544AlaMet: 1.544 ± 1.762
0.0AlaAsn: 0.0 ± 0.0
0.772AlaPro: 0.772 ± 0.514
1.544AlaGln: 1.544 ± 1.028
3.089AlaArg: 3.089 ± 1.459
6.178AlaSer: 6.178 ± 1.782
6.178AlaThr: 6.178 ± 3.207
3.089AlaVal: 3.089 ± 1.728
0.0AlaTrp: 0.0 ± 0.0
3.089AlaTyr: 3.089 ± 1.155
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.772CysCys: 0.772 ± 0.703
1.544CysAsp: 1.544 ± 1.08
1.544CysGlu: 1.544 ± 1.044
1.544CysPhe: 1.544 ± 1.406
0.772CysGly: 0.772 ± 0.703
0.0CysHis: 0.0 ± 0.0
0.772CysIle: 0.772 ± 0.703
0.772CysLys: 0.772 ± 1.001
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.544CysAsn: 1.544 ± 0.998
0.772CysPro: 0.772 ± 0.703
0.772CysGln: 0.772 ± 1.057
1.544CysArg: 1.544 ± 1.406
1.544CysSer: 1.544 ± 1.406
0.772CysThr: 0.772 ± 1.007
3.089CysVal: 3.089 ± 0.87
0.772CysTrp: 0.772 ± 0.703
0.772CysTyr: 0.772 ± 0.703
0.0CysXaa: 0.0 ± 0.0
Asp
2.317AspAla: 2.317 ± 1.543
2.317AspCys: 2.317 ± 1.519
1.544AspAsp: 1.544 ± 1.196
6.95AspGlu: 6.95 ± 1.071
4.633AspPhe: 4.633 ± 1.749
1.544AspGly: 1.544 ± 0.578
0.0AspHis: 0.0 ± 0.0
3.861AspIle: 3.861 ± 1.196
3.861AspLys: 3.861 ± 2.799
8.494AspLeu: 8.494 ± 0.906
0.0AspMet: 0.0 ± 0.0
4.633AspAsn: 4.633 ± 2.113
1.544AspPro: 1.544 ± 1.08
1.544AspGln: 1.544 ± 1.405
1.544AspArg: 1.544 ± 1.02
1.544AspSer: 1.544 ± 0.578
1.544AspThr: 1.544 ± 1.028
3.861AspVal: 3.861 ± 1.085
0.0AspTrp: 0.0 ± 0.0
5.405AspTyr: 5.405 ± 1.882
0.0AspXaa: 0.0 ± 0.0
Glu
2.317GluAla: 2.317 ± 1.311
3.089GluCys: 3.089 ± 1.567
1.544GluAsp: 1.544 ± 0.578
2.317GluGlu: 2.317 ± 1.92
4.633GluPhe: 4.633 ± 2.003
1.544GluGly: 1.544 ± 1.196
2.317GluHis: 2.317 ± 0.838
3.089GluIle: 3.089 ± 1.939
5.405GluLys: 5.405 ± 2.517
2.317GluLeu: 2.317 ± 1.472
3.089GluMet: 3.089 ± 1.265
9.266GluAsn: 9.266 ± 1.93
1.544GluPro: 1.544 ± 2.014
3.861GluGln: 3.861 ± 1.95
6.178GluArg: 6.178 ± 3.387
4.633GluSer: 4.633 ± 2.993
3.089GluThr: 3.089 ± 1.851
3.861GluVal: 3.861 ± 1.733
0.772GluTrp: 0.772 ± 0.514
3.861GluTyr: 3.861 ± 1.344
0.0GluXaa: 0.0 ± 0.0
Phe
2.317PheAla: 2.317 ± 1.232
0.0PheCys: 0.0 ± 0.0
3.089PheAsp: 3.089 ± 1.155
3.861PheGlu: 3.861 ± 1.733
2.317PhePhe: 2.317 ± 1.108
4.633PheGly: 4.633 ± 0.866
0.0PheHis: 0.0 ± 0.0
6.178PheIle: 6.178 ± 1.948
2.317PheLys: 2.317 ± 1.746
1.544PheLeu: 1.544 ± 0.578
4.633PheMet: 4.633 ± 1.77
3.861PheAsn: 3.861 ± 2.038
1.544PhePro: 1.544 ± 1.044
1.544PheGln: 1.544 ± 1.196
0.772PheArg: 0.772 ± 0.514
1.544PheSer: 1.544 ± 1.044
2.317PheThr: 2.317 ± 1.108
0.772PheVal: 0.772 ± 0.514
0.772PheTrp: 0.772 ± 0.514
0.772PheTyr: 0.772 ± 0.514
0.0PheXaa: 0.0 ± 0.0
Gly
2.317GlyAla: 2.317 ± 1.398
0.772GlyCys: 0.772 ± 0.703
3.089GlyAsp: 3.089 ± 2.057
5.405GlyGlu: 5.405 ± 1.856
2.317GlyPhe: 2.317 ± 1.519
2.317GlyGly: 2.317 ± 1.398
0.772GlyHis: 0.772 ± 0.514
3.861GlyIle: 3.861 ± 1.491
3.089GlyLys: 3.089 ± 1.854
3.089GlyLeu: 3.089 ± 1.265
2.317GlyMet: 2.317 ± 1.217
1.544GlyAsn: 1.544 ± 1.028
0.0GlyPro: 0.0 ± 0.0
3.861GlyGln: 3.861 ± 1.887
0.772GlyArg: 0.772 ± 0.703
6.178GlySer: 6.178 ± 2.339
3.861GlyThr: 3.861 ± 1.886
5.405GlyVal: 5.405 ± 2.983
0.0GlyTrp: 0.0 ± 0.0
6.178GlyTyr: 6.178 ± 1.388
0.0GlyXaa: 0.0 ± 0.0
His
1.544HisAla: 1.544 ± 1.406
0.772HisCys: 0.772 ± 0.514
0.772HisAsp: 0.772 ± 0.514
0.772HisGlu: 0.772 ± 0.703
3.861HisPhe: 3.861 ± 1.344
0.772HisGly: 0.772 ± 0.514
0.0HisHis: 0.0 ± 0.0
0.772HisIle: 0.772 ± 0.514
0.772HisLys: 0.772 ± 0.703
3.089HisLeu: 3.089 ± 1.155
0.0HisMet: 0.0 ± 0.0
0.772HisAsn: 0.772 ± 0.703
0.0HisPro: 0.0 ± 0.0
0.772HisGln: 0.772 ± 0.514
0.0HisArg: 0.0 ± 0.0
2.317HisSer: 2.317 ± 1.543
0.0HisThr: 0.0 ± 0.0
0.772HisVal: 0.772 ± 1.001
1.544HisTrp: 1.544 ± 0.578
0.772HisTyr: 0.772 ± 0.703
0.0HisXaa: 0.0 ± 0.0
Ile
3.089IleAla: 3.089 ± 1.145
1.544IleCys: 1.544 ± 1.02
4.633IleAsp: 4.633 ± 1.099
5.405IleGlu: 5.405 ± 2.528
0.772IlePhe: 0.772 ± 0.703
4.633IleGly: 4.633 ± 1.214
1.544IleHis: 1.544 ± 0.578
2.317IleIle: 2.317 ± 1.956
1.544IleLys: 1.544 ± 1.406
3.089IleLeu: 3.089 ± 1.145
0.772IleMet: 0.772 ± 0.514
2.317IleAsn: 2.317 ± 1.232
3.861IlePro: 3.861 ± 2.146
2.317IleGln: 2.317 ± 1.232
2.317IleArg: 2.317 ± 1.369
3.089IleSer: 3.089 ± 1.652
3.089IleThr: 3.089 ± 1.265
3.861IleVal: 3.861 ± 1.739
0.772IleTrp: 0.772 ± 0.514
3.089IleTyr: 3.089 ± 0.977
0.0IleXaa: 0.0 ± 0.0
Lys
3.089LysAla: 3.089 ± 2.53
0.772LysCys: 0.772 ± 0.703
7.722LysAsp: 7.722 ± 2.508
5.405LysGlu: 5.405 ± 2.463
5.405LysPhe: 5.405 ± 1.519
4.633LysGly: 4.633 ± 1.753
1.544LysHis: 1.544 ± 1.406
1.544LysIle: 1.544 ± 1.724
9.266LysLys: 9.266 ± 7.554
3.861LysLeu: 3.861 ± 2.881
3.861LysMet: 3.861 ± 2.003
4.633LysAsn: 4.633 ± 2.668
0.772LysPro: 0.772 ± 1.007
1.544LysGln: 1.544 ± 1.724
6.178LysArg: 6.178 ± 2.426
3.861LysSer: 3.861 ± 1.776
3.861LysThr: 3.861 ± 2.044
4.633LysVal: 4.633 ± 2.433
0.772LysTrp: 0.772 ± 0.703
0.772LysTyr: 0.772 ± 0.703
0.0LysXaa: 0.0 ± 0.0
Leu
3.089LeuAla: 3.089 ± 1.265
0.772LeuCys: 0.772 ± 0.703
3.089LeuAsp: 3.089 ± 0.931
4.633LeuGlu: 4.633 ± 2.96
0.772LeuPhe: 0.772 ± 0.703
6.178LeuGly: 6.178 ± 2.367
1.544LeuHis: 1.544 ± 1.406
3.089LeuIle: 3.089 ± 1.265
5.405LeuLys: 5.405 ± 1.856
2.317LeuLeu: 2.317 ± 0.812
1.544LeuMet: 1.544 ± 1.405
4.633LeuAsn: 4.633 ± 1.24
6.178LeuPro: 6.178 ± 1.456
3.089LeuGln: 3.089 ± 1.265
3.861LeuArg: 3.861 ± 1.719
3.861LeuSer: 3.861 ± 1.837
6.178LeuThr: 6.178 ± 1.261
6.95LeuVal: 6.95 ± 1.261
0.0LeuTrp: 0.0 ± 0.0
2.317LeuTyr: 2.317 ± 1.472
0.0LeuXaa: 0.0 ± 0.0
Met
1.544MetAla: 1.544 ± 0.925
0.0MetCys: 0.0 ± 0.0
1.544MetAsp: 1.544 ± 0.925
0.772MetGlu: 0.772 ± 1.001
0.772MetPhe: 0.772 ± 1.186
0.772MetGly: 0.772 ± 0.514
0.772MetHis: 0.772 ± 0.514
2.317MetIle: 2.317 ± 1.48
3.861MetLys: 3.861 ± 2.232
2.317MetLeu: 2.317 ± 1.244
1.544MetMet: 1.544 ± 1.739
3.861MetAsn: 3.861 ± 1.696
0.772MetPro: 0.772 ± 0.514
0.772MetGln: 0.772 ± 0.514
1.544MetArg: 1.544 ± 0.578
3.089MetSer: 3.089 ± 2.057
0.772MetThr: 0.772 ± 0.703
0.772MetVal: 0.772 ± 0.703
0.772MetTrp: 0.772 ± 0.703
1.544MetTyr: 1.544 ± 1.593
0.0MetXaa: 0.0 ± 0.0
Asn
6.178AsnAla: 6.178 ± 1.718
0.772AsnCys: 0.772 ± 0.703
1.544AsnAsp: 1.544 ± 0.998
3.861AsnGlu: 3.861 ± 1.916
3.861AsnPhe: 3.861 ± 0.738
3.089AsnGly: 3.089 ± 1.265
0.0AsnHis: 0.0 ± 0.0
0.772AsnIle: 0.772 ± 0.703
1.544AsnLys: 1.544 ± 0.578
3.861AsnLeu: 3.861 ± 1.592
0.0AsnMet: 0.0 ± 0.0
1.544AsnAsn: 1.544 ± 0.998
6.178AsnPro: 6.178 ± 1.889
2.317AsnGln: 2.317 ± 1.448
1.544AsnArg: 1.544 ± 0.998
3.861AsnSer: 3.861 ± 1.12
3.089AsnThr: 3.089 ± 2.91
3.861AsnVal: 3.861 ± 1.739
0.772AsnTrp: 0.772 ± 0.703
3.861AsnTyr: 3.861 ± 2.677
0.0AsnXaa: 0.0 ± 0.0
Pro
3.861ProAla: 3.861 ± 1.718
0.772ProCys: 0.772 ± 0.703
0.772ProAsp: 0.772 ± 0.514
3.861ProGlu: 3.861 ± 1.95
0.772ProPhe: 0.772 ± 0.514
2.317ProGly: 2.317 ± 1.543
0.772ProHis: 0.772 ± 0.703
5.405ProIle: 5.405 ± 2.278
0.772ProLys: 0.772 ± 1.186
4.633ProLeu: 4.633 ± 1.418
1.544ProMet: 1.544 ± 0.578
0.0ProAsn: 0.0 ± 0.0
1.544ProPro: 1.544 ± 0.578
5.405ProGln: 5.405 ± 1.882
0.0ProArg: 0.0 ± 0.0
4.633ProSer: 4.633 ± 4.847
1.544ProThr: 1.544 ± 0.925
4.633ProVal: 4.633 ± 0.866
0.772ProTrp: 0.772 ± 0.514
0.772ProTyr: 0.772 ± 1.007
0.0ProXaa: 0.0 ± 0.0
Gln
1.544GlnAla: 1.544 ± 1.028
0.0GlnCys: 0.0 ± 0.0
1.544GlnAsp: 1.544 ± 2.014
5.405GlnGlu: 5.405 ± 2.055
2.317GlnPhe: 2.317 ± 1.48
2.317GlnGly: 2.317 ± 1.232
0.772GlnHis: 0.772 ± 0.514
2.317GlnIle: 2.317 ± 1.108
2.317GlnLys: 2.317 ± 0.838
3.861GlnLeu: 3.861 ± 1.981
2.317GlnMet: 2.317 ± 1.384
2.317GlnAsn: 2.317 ± 1.653
1.544GlnPro: 1.544 ± 1.19
3.089GlnGln: 3.089 ± 1.54
0.772GlnArg: 0.772 ± 0.514
3.089GlnSer: 3.089 ± 2.85
3.089GlnThr: 3.089 ± 1.284
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
3.089GlnTyr: 3.089 ± 1.344
0.0GlnXaa: 0.0 ± 0.0
Arg
3.089ArgAla: 3.089 ± 1.145
0.772ArgCys: 0.772 ± 1.001
2.317ArgAsp: 2.317 ± 1.108
0.0ArgGlu: 0.0 ± 0.0
0.772ArgPhe: 0.772 ± 1.186
2.317ArgGly: 2.317 ± 1.398
0.0ArgHis: 0.0 ± 0.0
2.317ArgIle: 2.317 ± 0.838
6.95ArgLys: 6.95 ± 3.24
6.178ArgLeu: 6.178 ± 1.929
1.544ArgMet: 1.544 ± 1.196
0.0ArgAsn: 0.0 ± 0.0
1.544ArgPro: 1.544 ± 1.028
0.772ArgGln: 0.772 ± 0.514
0.0ArgArg: 0.0 ± 0.0
6.178ArgSer: 6.178 ± 2.053
2.317ArgThr: 2.317 ± 0.838
1.544ArgVal: 1.544 ± 1.028
0.772ArgTrp: 0.772 ± 0.514
3.089ArgTyr: 3.089 ± 0.728
0.0ArgXaa: 0.0 ± 0.0
Ser
4.633SerAla: 4.633 ± 2.348
0.772SerCys: 0.772 ± 1.001
4.633SerAsp: 4.633 ± 1.623
6.178SerGlu: 6.178 ± 1.567
2.317SerPhe: 2.317 ± 0.838
2.317SerGly: 2.317 ± 1.398
2.317SerHis: 2.317 ± 1.543
3.861SerIle: 3.861 ± 2.183
8.494SerLys: 8.494 ± 2.526
7.722SerLeu: 7.722 ± 2.159
0.772SerMet: 0.772 ± 1.001
3.861SerAsn: 3.861 ± 1.509
1.544SerPro: 1.544 ± 0.578
2.317SerGln: 2.317 ± 1.18
3.089SerArg: 3.089 ± 2.38
3.089SerSer: 3.089 ± 0.87
9.266SerThr: 9.266 ± 2.683
2.317SerVal: 2.317 ± 1.232
0.772SerTrp: 0.772 ± 0.703
5.405SerTyr: 5.405 ± 1.809
0.0SerXaa: 0.0 ± 0.0
Thr
6.178ThrAla: 6.178 ± 3.319
0.772ThrCys: 0.772 ± 0.703
4.633ThrAsp: 4.633 ± 0.934
3.861ThrGlu: 3.861 ± 1.592
0.772ThrPhe: 0.772 ± 0.514
6.178ThrGly: 6.178 ± 1.718
0.772ThrHis: 0.772 ± 0.703
1.544ThrIle: 1.544 ± 0.998
2.317ThrLys: 2.317 ± 2.222
4.633ThrLeu: 4.633 ± 0.934
1.544ThrMet: 1.544 ± 0.925
1.544ThrAsn: 1.544 ± 1.044
6.95ThrPro: 6.95 ± 2.598
0.772ThrGln: 0.772 ± 0.514
2.317ThrArg: 2.317 ± 1.543
4.633ThrSer: 4.633 ± 1.854
4.633ThrThr: 4.633 ± 2.826
5.405ThrVal: 5.405 ± 3.679
0.0ThrTrp: 0.0 ± 0.0
1.544ThrTyr: 1.544 ± 1.406
0.0ThrXaa: 0.0 ± 0.0
Val
1.544ValAla: 1.544 ± 0.925
2.317ValCys: 2.317 ± 1.472
4.633ValAsp: 4.633 ± 0.655
3.861ValGlu: 3.861 ± 2.955
2.317ValPhe: 2.317 ± 1.232
5.405ValGly: 5.405 ± 1.602
0.772ValHis: 0.772 ± 0.514
2.317ValIle: 2.317 ± 0.838
6.178ValLys: 6.178 ± 3.13
2.317ValLeu: 2.317 ± 2.109
1.544ValMet: 1.544 ± 0.998
1.544ValAsn: 1.544 ± 1.08
4.633ValPro: 4.633 ± 3.085
0.772ValGln: 0.772 ± 1.007
4.633ValArg: 4.633 ± 1.483
5.405ValSer: 5.405 ± 1.218
3.089ValThr: 3.089 ± 1.14
6.95ValVal: 6.95 ± 2.598
0.772ValTrp: 0.772 ± 0.514
5.405ValTyr: 5.405 ± 2.829
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.772TrpCys: 0.772 ± 0.514
0.0TrpAsp: 0.0 ± 0.0
0.772TrpGlu: 0.772 ± 0.514
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
2.317TrpHis: 2.317 ± 0.838
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.772TrpPro: 0.772 ± 0.514
0.0TrpGln: 0.0 ± 0.0
0.772TrpArg: 0.772 ± 0.703
3.089TrpSer: 3.089 ± 1.854
0.772TrpThr: 0.772 ± 0.514
0.772TrpVal: 0.772 ± 0.514
0.0TrpTrp: 0.0 ± 0.0
1.544TrpTyr: 1.544 ± 0.578
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.544TyrAla: 1.544 ± 0.578
0.0TyrCys: 0.0 ± 0.0
5.405TyrAsp: 5.405 ± 2.46
2.317TyrGlu: 2.317 ± 1.555
3.089TyrPhe: 3.089 ± 1.603
3.089TyrGly: 3.089 ± 1.265
0.772TyrHis: 0.772 ± 1.001
3.861TyrIle: 3.861 ± 1.003
5.405TyrLys: 5.405 ± 2.463
3.089TyrLeu: 3.089 ± 0.728
0.772TyrMet: 0.772 ± 0.514
4.633TyrAsn: 4.633 ± 1.733
2.317TyrPro: 2.317 ± 1.108
4.633TyrGln: 4.633 ± 3.005
1.544TyrArg: 1.544 ± 0.578
3.861TyrSer: 3.861 ± 1.719
1.544TyrThr: 1.544 ± 0.925
3.861TyrVal: 3.861 ± 2.749
1.544TyrTrp: 1.544 ± 1.028
5.405TyrTyr: 5.405 ± 2.278
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1296 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski