Amino acid dipepetide frequency for Fuerstia marisgermanicae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.462AlaAla: 12.462 ± 0.1	1.089AlaCys: 1.089 ± 0.023	6.922AlaAsp: 6.922 ± 0.067	6.598AlaGlu: 6.598 ± 0.083	3.504AlaPhe: 3.504 ± 0.036	7.736AlaGly: 7.736 ± 0.106	1.67AlaHis: 1.67 ± 0.029	5.298AlaIle: 5.298 ± 0.057	3.938AlaLys: 3.938 ± 0.057	7.768AlaLeu: 7.768 ± 0.068	2.426AlaMet: 2.426 ± 0.038	3.405AlaAsn: 3.405 ± 0.05	3.796AlaPro: 3.796 ± 0.047	3.058AlaGln: 3.058 ± 0.037	5.095AlaArg: 5.095 ± 0.066	6.143AlaSer: 6.143 ± 0.067	6.452AlaThr: 6.452 ± 0.098	7.568AlaVal: 7.568 ± 0.059	1.355AlaTrp: 1.355 ± 0.027	1.805AlaTyr: 1.805 ± 0.029	0.0AlaXaa: 0.0 ± 0.0
Cys	0.852CysAla: 0.852 ± 0.023	0.276CysCys: 0.276 ± 0.013	0.759CysAsp: 0.759 ± 0.019	0.675CysGlu: 0.675 ± 0.016	0.496CysPhe: 0.496 ± 0.015	1.094CysGly: 1.094 ± 0.032	0.462CysHis: 0.462 ± 0.017	0.463CysIle: 0.463 ± 0.016	0.29CysLys: 0.29 ± 0.011	1.129CysLeu: 1.129 ± 0.023	0.212CysMet: 0.212 ± 0.008	0.315CysAsn: 0.315 ± 0.012	0.572CysPro: 0.572 ± 0.019	0.383CysGln: 0.383 ± 0.013	0.842CysArg: 0.842 ± 0.022	0.739CysSer: 0.739 ± 0.021	0.51CysThr: 0.51 ± 0.015	0.913CysVal: 0.913 ± 0.023	0.19CysTrp: 0.19 ± 0.009	0.329CysTyr: 0.329 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.509AspAla: 6.509 ± 0.083	0.668AspCys: 0.668 ± 0.017	4.795AspAsp: 4.795 ± 0.085	4.316AspGlu: 4.316 ± 0.045	2.587AspPhe: 2.587 ± 0.034	6.218AspGly: 6.218 ± 0.105	1.469AspHis: 1.469 ± 0.029	2.916AspIle: 2.916 ± 0.049	2.028AspLys: 2.028 ± 0.034	5.692AspLeu: 5.692 ± 0.046	1.112AspMet: 1.112 ± 0.024	2.099AspAsn: 2.099 ± 0.049	3.159AspPro: 3.159 ± 0.046	2.386AspGln: 2.386 ± 0.032	4.054AspArg: 4.054 ± 0.054	4.117AspSer: 4.117 ± 0.057	3.184AspThr: 3.184 ± 0.087	5.035AspVal: 5.035 ± 0.065	1.052AspTrp: 1.052 ± 0.023	1.616AspTyr: 1.616 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	5.783GluAla: 5.783 ± 0.061	0.587GluCys: 0.587 ± 0.017	3.221GluAsp: 3.221 ± 0.046	3.32GluGlu: 3.32 ± 0.055	2.581GluPhe: 2.581 ± 0.04	3.552GluGly: 3.552 ± 0.048	1.334GluHis: 1.334 ± 0.025	3.186GluIle: 3.186 ± 0.038	2.383GluLys: 2.383 ± 0.044	6.476GluLeu: 6.476 ± 0.067	1.41GluMet: 1.41 ± 0.028	1.967GluAsn: 1.967 ± 0.028	2.648GluPro: 2.648 ± 0.036	2.853GluGln: 2.853 ± 0.048	3.759GluArg: 3.759 ± 0.055	3.993GluSer: 3.993 ± 0.043	3.562GluThr: 3.562 ± 0.036	4.099GluVal: 4.099 ± 0.045	0.87GluTrp: 0.87 ± 0.02	1.356GluTyr: 1.356 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	3.798PheAla: 3.798 ± 0.042	0.522PheCys: 0.522 ± 0.016	2.955PheAsp: 2.955 ± 0.036	2.443PheGlu: 2.443 ± 0.036	1.374PhePhe: 1.374 ± 0.023	3.394PheGly: 3.394 ± 0.045	0.887PheHis: 0.887 ± 0.021	1.429PheIle: 1.429 ± 0.026	0.982PheLys: 0.982 ± 0.021	3.371PheLeu: 3.371 ± 0.047	0.694PheMet: 0.694 ± 0.019	1.3PheAsn: 1.3 ± 0.028	1.707PhePro: 1.707 ± 0.026	1.396PheGln: 1.396 ± 0.026	2.625PheArg: 2.625 ± 0.037	2.57PheSer: 2.57 ± 0.039	2.213PheThr: 2.213 ± 0.045	2.999PheVal: 2.999 ± 0.041	0.547PheTrp: 0.547 ± 0.016	0.903PheTyr: 0.903 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	5.793GlyAla: 5.793 ± 0.082	0.988GlyCys: 0.988 ± 0.024	5.08GlyAsp: 5.08 ± 0.097	4.283GlyGlu: 4.283 ± 0.042	3.072GlyPhe: 3.072 ± 0.04	6.624GlyGly: 6.624 ± 0.139	1.751GlyHis: 1.751 ± 0.029	3.873GlyIle: 3.873 ± 0.048	3.359GlyLys: 3.359 ± 0.053	6.644GlyLeu: 6.644 ± 0.061	1.92GlyMet: 1.92 ± 0.038	3.014GlyAsn: 3.014 ± 0.093	2.909GlyPro: 2.909 ± 0.04	3.06GlyGln: 3.06 ± 0.054	4.984GlyArg: 4.984 ± 0.053	5.064GlySer: 5.064 ± 0.1	5.149GlyThr: 5.149 ± 0.14	5.318GlyVal: 5.318 ± 0.069	1.233GlyTrp: 1.233 ± 0.027	1.977GlyTyr: 1.977 ± 0.032	0.0GlyXaa: 0.0 ± 0.0
His	2.034HisAla: 2.034 ± 0.032	0.328HisCys: 0.328 ± 0.012	1.447HisAsp: 1.447 ± 0.025	1.269HisGlu: 1.269 ± 0.023	0.958HisPhe: 0.958 ± 0.021	1.888HisGly: 1.888 ± 0.033	0.646HisHis: 0.646 ± 0.02	0.948HisIle: 0.948 ± 0.018	0.717HisLys: 0.717 ± 0.018	2.069HisLeu: 2.069 ± 0.034	0.387HisMet: 0.387 ± 0.013	0.798HisAsn: 0.798 ± 0.02	1.329HisPro: 1.329 ± 0.027	0.869HisGln: 0.869 ± 0.023	1.584HisArg: 1.584 ± 0.032	1.416HisSer: 1.416 ± 0.026	1.086HisThr: 1.086 ± 0.022	1.625HisVal: 1.625 ± 0.03	0.426HisTrp: 0.426 ± 0.015	0.587HisTyr: 0.587 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	5.296IleAla: 5.296 ± 0.047	0.658IleCys: 0.658 ± 0.019	3.833IleAsp: 3.833 ± 0.063	3.195IleGlu: 3.195 ± 0.043	1.481IlePhe: 1.481 ± 0.03	3.995IleGly: 3.995 ± 0.065	1.091IleHis: 1.091 ± 0.021	1.854IleIle: 1.854 ± 0.032	1.445IleLys: 1.445 ± 0.026	4.012IleLeu: 4.012 ± 0.045	0.813IleMet: 0.813 ± 0.019	1.67IleAsn: 1.67 ± 0.037	2.47IlePro: 2.47 ± 0.039	1.703IleGln: 1.703 ± 0.029	3.286IleArg: 3.286 ± 0.036	3.186IleSer: 3.186 ± 0.046	3.066IleThr: 3.066 ± 0.095	4.075IleVal: 4.075 ± 0.047	0.603IleTrp: 0.603 ± 0.016	1.077IleTyr: 1.077 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	3.701LysAla: 3.701 ± 0.061	0.374LysCys: 0.374 ± 0.012	2.071LysAsp: 2.071 ± 0.041	1.966LysGlu: 1.966 ± 0.04	1.281LysPhe: 1.281 ± 0.025	2.161LysGly: 2.161 ± 0.04	0.908LysHis: 0.908 ± 0.023	1.804LysIle: 1.804 ± 0.03	1.888LysLys: 1.888 ± 0.053	3.94LysLeu: 3.94 ± 0.056	0.89LysMet: 0.89 ± 0.021	1.291LysAsn: 1.291 ± 0.024	2.371LysPro: 2.371 ± 0.045	1.808LysGln: 1.808 ± 0.039	2.448LysArg: 2.448 ± 0.042	2.582LysSer: 2.582 ± 0.041	2.319LysThr: 2.319 ± 0.038	2.578LysVal: 2.578 ± 0.039	0.567LysTrp: 0.567 ± 0.017	0.874LysTyr: 0.874 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	9.739LeuAla: 9.739 ± 0.087	1.107LeuCys: 1.107 ± 0.027	5.353LeuAsp: 5.353 ± 0.048	5.013LeuGlu: 5.013 ± 0.048	3.339LeuPhe: 3.339 ± 0.04	6.013LeuGly: 6.013 ± 0.053	2.032LeuHis: 2.032 ± 0.033	4.507LeuIle: 4.507 ± 0.049	4.342LeuLys: 4.342 ± 0.058	9.77LeuLeu: 9.77 ± 0.106	2.047LeuMet: 2.047 ± 0.036	3.532LeuAsn: 3.532 ± 0.036	5.212LeuPro: 5.212 ± 0.063	4.237LeuGln: 4.237 ± 0.052	5.868LeuArg: 5.868 ± 0.063	6.359LeuSer: 6.359 ± 0.055	6.255LeuThr: 6.255 ± 0.079	6.263LeuVal: 6.263 ± 0.054	1.184LeuTrp: 1.184 ± 0.025	1.919LeuTyr: 1.919 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.209MetAla: 2.209 ± 0.034	0.207MetCys: 0.207 ± 0.01	1.062MetAsp: 1.062 ± 0.024	1.089MetGlu: 1.089 ± 0.021	0.776MetPhe: 0.776 ± 0.02	1.349MetGly: 1.349 ± 0.034	0.458MetHis: 0.458 ± 0.015	1.036MetIle: 1.036 ± 0.024	1.148MetLys: 1.148 ± 0.026	2.305MetLeu: 2.305 ± 0.04	0.56MetMet: 0.56 ± 0.016	0.887MetAsn: 0.887 ± 0.02	1.355MetPro: 1.355 ± 0.026	0.987MetGln: 0.987 ± 0.022	1.207MetArg: 1.207 ± 0.025	1.576MetSer: 1.576 ± 0.029	1.53MetThr: 1.53 ± 0.025	1.402MetVal: 1.402 ± 0.026	0.261MetTrp: 0.261 ± 0.011	0.42MetTyr: 0.42 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.461AsnAla: 3.461 ± 0.049	0.404AsnCys: 0.404 ± 0.014	2.457AsnAsp: 2.457 ± 0.072	1.92AsnGlu: 1.92 ± 0.036	1.224AsnPhe: 1.224 ± 0.023	3.319AsnGly: 3.319 ± 0.068	0.801AsnHis: 0.801 ± 0.02	1.569AsnIle: 1.569 ± 0.034	1.026AsnLys: 1.026 ± 0.025	3.147AsnLeu: 3.147 ± 0.043	0.648AsnMet: 0.648 ± 0.015	1.343AsnAsn: 1.343 ± 0.04	2.068AsnPro: 2.068 ± 0.029	1.295AsnGln: 1.295 ± 0.025	2.334AsnArg: 2.334 ± 0.032	2.459AsnSer: 2.459 ± 0.048	1.89AsnThr: 1.89 ± 0.057	2.732AsnVal: 2.732 ± 0.049	0.549AsnTrp: 0.549 ± 0.018	0.855AsnTyr: 0.855 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	4.949ProAla: 4.949 ± 0.052	0.347ProCys: 0.347 ± 0.012	3.878ProAsp: 3.878 ± 0.047	3.726ProGlu: 3.726 ± 0.045	1.82ProPhe: 1.82 ± 0.032	3.808ProGly: 3.808 ± 0.049	1.093ProHis: 1.093 ± 0.023	2.292ProIle: 2.292 ± 0.034	1.93ProLys: 1.93 ± 0.038	4.179ProLeu: 4.179 ± 0.049	1.027ProMet: 1.027 ± 0.021	1.897ProAsn: 1.897 ± 0.028	2.712ProPro: 2.712 ± 0.048	2.044ProGln: 2.044 ± 0.037	2.457ProArg: 2.457 ± 0.038	3.204ProSer: 3.204 ± 0.036	3.057ProThr: 3.057 ± 0.045	3.863ProVal: 3.863 ± 0.048	0.713ProTrp: 0.713 ± 0.018	1.017ProTyr: 1.017 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.625GlnAla: 3.625 ± 0.046	0.419GlnCys: 0.419 ± 0.013	1.722GlnAsp: 1.722 ± 0.026	1.83GlnGlu: 1.83 ± 0.032	1.59GlnPhe: 1.59 ± 0.027	2.09GlnGly: 2.09 ± 0.046	1.141GlnHis: 1.141 ± 0.022	2.236GlnIle: 2.236 ± 0.032	1.757GlnLys: 1.757 ± 0.031	4.502GlnLeu: 4.502 ± 0.056	0.99GlnMet: 0.99 ± 0.023	1.366GlnAsn: 1.366 ± 0.025	2.427GlnPro: 2.427 ± 0.042	2.702GlnGln: 2.702 ± 0.061	2.884GlnArg: 2.884 ± 0.046	2.583GlnSer: 2.583 ± 0.035	2.545GlnThr: 2.545 ± 0.037	2.509GlnVal: 2.509 ± 0.036	0.569GlnTrp: 0.569 ± 0.015	0.858GlnTyr: 0.858 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	4.38ArgAla: 4.38 ± 0.052	0.757ArgCys: 0.757 ± 0.021	3.688ArgAsp: 3.688 ± 0.045	3.659ArgGlu: 3.659 ± 0.055	2.836ArgPhe: 2.836 ± 0.042	3.741ArgGly: 3.741 ± 0.052	1.572ArgHis: 1.572 ± 0.027	3.635ArgIle: 3.635 ± 0.04	2.579ArgLys: 2.579 ± 0.048	6.517ArgLeu: 6.517 ± 0.075	1.718ArgMet: 1.718 ± 0.032	2.332ArgAsn: 2.332 ± 0.033	2.995ArgPro: 2.995 ± 0.045	2.816ArgGln: 2.816 ± 0.05	4.968ArgArg: 4.968 ± 0.071	4.151ArgSer: 4.151 ± 0.057	3.497ArgThr: 3.497 ± 0.045	4.174ArgVal: 4.174 ± 0.047	1.079ArgTrp: 1.079 ± 0.022	1.684ArgTyr: 1.684 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	6.26SerAla: 6.26 ± 0.073	0.679SerCys: 0.679 ± 0.019	4.515SerAsp: 4.515 ± 0.056	3.963SerGlu: 3.963 ± 0.048	2.428SerPhe: 2.428 ± 0.036	6.12SerGly: 6.12 ± 0.1	1.422SerHis: 1.422 ± 0.026	3.106SerIle: 3.106 ± 0.052	2.203SerLys: 2.203 ± 0.036	6.244SerLeu: 6.244 ± 0.057	1.432SerMet: 1.432 ± 0.026	2.318SerAsn: 2.318 ± 0.043	3.506SerPro: 3.506 ± 0.043	2.396SerGln: 2.396 ± 0.032	4.001SerArg: 4.001 ± 0.054	4.536SerSer: 4.536 ± 0.06	3.877SerThr: 3.877 ± 0.067	4.972SerVal: 4.972 ± 0.058	0.897SerTrp: 0.897 ± 0.02	1.424SerTyr: 1.424 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	6.392ThrAla: 6.392 ± 0.101	0.586ThrCys: 0.586 ± 0.02	4.02ThrAsp: 4.02 ± 0.093	3.294ThrGlu: 3.294 ± 0.039	2.46ThrPhe: 2.46 ± 0.046	5.136ThrGly: 5.136 ± 0.103	1.197ThrHis: 1.197 ± 0.022	3.405ThrIle: 3.405 ± 0.109	1.936ThrLys: 1.936 ± 0.036	5.785ThrLeu: 5.785 ± 0.077	1.172ThrMet: 1.172 ± 0.023	2.058ThrAsn: 2.058 ± 0.052	3.385ThrPro: 3.385 ± 0.048	2.05ThrGln: 2.05 ± 0.031	2.954ThrArg: 2.954 ± 0.042	4.108ThrSer: 4.108 ± 0.077	3.855ThrThr: 3.855 ± 0.113	5.147ThrVal: 5.147 ± 0.144	0.888ThrTrp: 0.888 ± 0.019	1.317ThrTyr: 1.317 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	7.808ValAla: 7.808 ± 0.063	0.966ValCys: 0.966 ± 0.024	4.859ValAsp: 4.859 ± 0.074	4.382ValGlu: 4.382 ± 0.054	2.717ValPhe: 2.717 ± 0.034	5.076ValGly: 5.076 ± 0.06	1.469ValHis: 1.469 ± 0.026	3.675ValIle: 3.675 ± 0.056	2.433ValLys: 2.433 ± 0.036	6.73ValLeu: 6.73 ± 0.063	1.579ValMet: 1.579 ± 0.025	2.568ValAsn: 2.568 ± 0.053	3.649ValPro: 3.649 ± 0.044	2.582ValGln: 2.582 ± 0.036	4.614ValArg: 4.614 ± 0.053	5.008ValSer: 5.008 ± 0.063	5.028ValThr: 5.028 ± 0.124	6.061ValVal: 6.061 ± 0.055	1.02ValTrp: 1.02 ± 0.027	1.651ValTyr: 1.651 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.008TrpAla: 1.008 ± 0.021	0.202TrpCys: 0.202 ± 0.009	0.828TrpAsp: 0.828 ± 0.02	0.631TrpGlu: 0.631 ± 0.018	0.601TrpPhe: 0.601 ± 0.017	0.866TrpGly: 0.866 ± 0.022	0.431TrpHis: 0.431 ± 0.016	0.746TrpIle: 0.746 ± 0.018	0.773TrpLys: 0.773 ± 0.021	1.687TrpLeu: 1.687 ± 0.033	0.414TrpMet: 0.414 ± 0.014	0.62TrpAsn: 0.62 ± 0.018	0.69TrpPro: 0.69 ± 0.017	0.769TrpGln: 0.769 ± 0.019	0.982TrpArg: 0.982 ± 0.021	0.99TrpSer: 0.99 ± 0.023	0.877TrpThr: 0.877 ± 0.021	0.907TrpVal: 0.907 ± 0.023	0.268TrpTrp: 0.268 ± 0.012	0.374TrpTyr: 0.374 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.03TyrAla: 2.03 ± 0.035	0.336TyrCys: 0.336 ± 0.013	1.545TyrAsp: 1.545 ± 0.036	1.37TyrGlu: 1.37 ± 0.029	0.982TyrPhe: 0.982 ± 0.021	1.92TyrGly: 1.92 ± 0.033	0.577TyrHis: 0.577 ± 0.016	0.831TyrIle: 0.831 ± 0.018	0.668TyrLys: 0.668 ± 0.02	2.124TyrLeu: 2.124 ± 0.032	0.372TyrMet: 0.372 ± 0.012	0.721TyrAsn: 0.721 ± 0.018	1.05TyrPro: 1.05 ± 0.024	0.954TyrGln: 0.954 ± 0.021	1.83TyrArg: 1.83 ± 0.027	1.515TyrSer: 1.515 ± 0.026	1.192TyrThr: 1.192 ± 0.035	1.635TyrVal: 1.635 ± 0.028	0.392TyrTrp: 0.392 ± 0.013	0.629TyrTyr: 0.629 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6466 proteins (2532177 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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