Amino acid dipepetide frequency for Albidovulum inexpectatum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.071AlaAla: 17.071 ± 0.207	1.137AlaCys: 1.137 ± 0.04	6.912AlaAsp: 6.912 ± 0.106	8.943AlaGlu: 8.943 ± 0.123	4.183AlaPhe: 4.183 ± 0.08	10.549AlaGly: 10.549 ± 0.122	2.463AlaHis: 2.463 ± 0.054	6.633AlaIle: 6.633 ± 0.095	2.774AlaLys: 2.774 ± 0.073	13.867AlaLeu: 13.867 ± 0.178	4.02AlaMet: 4.02 ± 0.074	2.543AlaAsn: 2.543 ± 0.051	6.068AlaPro: 6.068 ± 0.108	4.443AlaGln: 4.443 ± 0.082	12.02AlaArg: 12.02 ± 0.141	5.037AlaSer: 5.037 ± 0.076	5.663AlaThr: 5.663 ± 0.096	8.218AlaVal: 8.218 ± 0.104	1.712AlaTrp: 1.712 ± 0.048	2.425AlaTyr: 2.425 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	1.072CysAla: 1.072 ± 0.035	0.1CysCys: 0.1 ± 0.011	0.611CysAsp: 0.611 ± 0.026	0.44CysGlu: 0.44 ± 0.024	0.293CysPhe: 0.293 ± 0.017	0.968CysGly: 0.968 ± 0.038	0.268CysHis: 0.268 ± 0.018	0.388CysIle: 0.388 ± 0.022	0.158CysLys: 0.158 ± 0.013	0.902CysLeu: 0.902 ± 0.037	0.161CysMet: 0.161 ± 0.014	0.195CysAsn: 0.195 ± 0.014	0.536CysPro: 0.536 ± 0.026	0.199CysGln: 0.199 ± 0.015	0.677CysArg: 0.677 ± 0.027	0.409CysSer: 0.409 ± 0.023	0.409CysThr: 0.409 ± 0.022	0.613CysVal: 0.613 ± 0.026	0.116CysTrp: 0.116 ± 0.011	0.18CysTyr: 0.18 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.908AspAla: 6.908 ± 0.104	0.504AspCys: 0.504 ± 0.023	3.344AspAsp: 3.344 ± 0.083	3.741AspGlu: 3.741 ± 0.068	2.326AspPhe: 2.326 ± 0.06	5.361AspGly: 5.361 ± 0.091	1.432AspHis: 1.432 ± 0.045	2.983AspIle: 2.983 ± 0.062	1.403AspLys: 1.403 ± 0.041	6.777AspLeu: 6.777 ± 0.085	1.543AspMet: 1.543 ± 0.046	1.109AspAsn: 1.109 ± 0.038	4.226AspPro: 4.226 ± 0.077	1.857AspGln: 1.857 ± 0.051	5.258AspArg: 5.258 ± 0.083	2.088AspSer: 2.088 ± 0.042	2.503AspThr: 2.503 ± 0.05	3.836AspVal: 3.836 ± 0.061	1.214AspTrp: 1.214 ± 0.038	1.398AspTyr: 1.398 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	7.919GluAla: 7.919 ± 0.107	0.434GluCys: 0.434 ± 0.022	3.268GluAsp: 3.268 ± 0.066	3.877GluGlu: 3.877 ± 0.074	1.917GluPhe: 1.917 ± 0.043	4.584GluGly: 4.584 ± 0.089	1.099GluHis: 1.099 ± 0.038	4.092GluIle: 4.092 ± 0.08	2.036GluLys: 2.036 ± 0.051	5.616GluLeu: 5.616 ± 0.077	1.738GluMet: 1.738 ± 0.042	1.466GluAsn: 1.466 ± 0.038	2.721GluPro: 2.721 ± 0.058	1.848GluGln: 1.848 ± 0.049	5.453GluArg: 5.453 ± 0.078	2.616GluSer: 2.616 ± 0.063	3.663GluThr: 3.663 ± 0.06	4.025GluVal: 4.025 ± 0.072	0.879GluTrp: 0.879 ± 0.029	1.043GluTyr: 1.043 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.275PheAla: 4.275 ± 0.075	0.411PheCys: 0.411 ± 0.019	2.764PheAsp: 2.764 ± 0.058	2.073PheGlu: 2.073 ± 0.053	1.278PhePhe: 1.278 ± 0.043	3.546PheGly: 3.546 ± 0.079	0.751PheHis: 0.751 ± 0.029	1.562PheIle: 1.562 ± 0.044	0.721PheLys: 0.721 ± 0.03	3.433PheLeu: 3.433 ± 0.068	0.789PheMet: 0.789 ± 0.031	0.856PheAsn: 0.856 ± 0.032	1.576PhePro: 1.576 ± 0.047	0.901PheGln: 0.901 ± 0.036	2.4PheArg: 2.4 ± 0.054	1.843PheSer: 1.843 ± 0.048	1.833PheThr: 1.833 ± 0.047	2.677PheVal: 2.677 ± 0.06	0.561PheTrp: 0.561 ± 0.023	0.869PheTyr: 0.869 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	10.028GlyAla: 10.028 ± 0.121	0.848GlyCys: 0.848 ± 0.035	4.451GlyAsp: 4.451 ± 0.066	4.584GlyGlu: 4.584 ± 0.082	3.434GlyPhe: 3.434 ± 0.067	7.264GlyGly: 7.264 ± 0.134	1.941GlyHis: 1.941 ± 0.057	4.619GlyIle: 4.619 ± 0.074	2.863GlyLys: 2.863 ± 0.059	9.284GlyLeu: 9.284 ± 0.11	2.523GlyMet: 2.523 ± 0.053	2.001GlyAsn: 2.001 ± 0.059	4.043GlyPro: 4.043 ± 0.066	3.169GlyGln: 3.169 ± 0.066	7.248GlyArg: 7.248 ± 0.093	3.901GlySer: 3.901 ± 0.072	4.258GlyThr: 4.258 ± 0.085	6.059GlyVal: 6.059 ± 0.092	1.551GlyTrp: 1.551 ± 0.042	2.05GlyTyr: 2.05 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.546HisAla: 2.546 ± 0.057	0.203HisCys: 0.203 ± 0.017	1.398HisAsp: 1.398 ± 0.041	1.199HisGlu: 1.199 ± 0.034	0.851HisPhe: 0.851 ± 0.036	1.994HisGly: 1.994 ± 0.05	0.537HisHis: 0.537 ± 0.025	0.828HisIle: 0.828 ± 0.028	0.399HisLys: 0.399 ± 0.021	2.163HisLeu: 2.163 ± 0.053	0.489HisMet: 0.489 ± 0.023	0.38HisAsn: 0.38 ± 0.019	1.391HisPro: 1.391 ± 0.046	0.545HisGln: 0.545 ± 0.025	1.549HisArg: 1.549 ± 0.046	0.833HisSer: 0.833 ± 0.031	0.649HisThr: 0.649 ± 0.026	1.879HisVal: 1.879 ± 0.04	0.329HisTrp: 0.329 ± 0.02	0.595HisTyr: 0.595 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	7.568IleAla: 7.568 ± 0.096	0.596IleCys: 0.596 ± 0.027	3.75IleAsp: 3.75 ± 0.075	3.993IleGlu: 3.993 ± 0.068	1.612IlePhe: 1.612 ± 0.043	4.965IleGly: 4.965 ± 0.08	1.078IleHis: 1.078 ± 0.036	2.048IleIle: 2.048 ± 0.051	1.161IleLys: 1.161 ± 0.039	5.385IleLeu: 5.385 ± 0.087	1.056IleMet: 1.056 ± 0.038	1.159IleAsn: 1.159 ± 0.035	2.5IlePro: 2.5 ± 0.054	1.166IleGln: 1.166 ± 0.035	4.118IleArg: 4.118 ± 0.064	2.618IleSer: 2.618 ± 0.058	2.535IleThr: 2.535 ± 0.058	4.369IleVal: 4.369 ± 0.078	0.716IleTrp: 0.716 ± 0.032	1.079IleTyr: 1.079 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	3.51LysAla: 3.51 ± 0.066	0.188LysCys: 0.188 ± 0.015	1.452LysAsp: 1.452 ± 0.041	1.378LysGlu: 1.378 ± 0.044	0.785LysPhe: 0.785 ± 0.026	2.397LysGly: 2.397 ± 0.051	0.483LysHis: 0.483 ± 0.023	1.447LysIle: 1.447 ± 0.043	0.993LysLys: 0.993 ± 0.043	2.546LysLeu: 2.546 ± 0.057	0.695LysMet: 0.695 ± 0.027	0.626LysAsn: 0.626 ± 0.027	1.622LysPro: 1.622 ± 0.046	0.676LysGln: 0.676 ± 0.027	2.04LysArg: 2.04 ± 0.057	1.459LysSer: 1.459 ± 0.042	1.536LysThr: 1.536 ± 0.044	2.125LysVal: 2.125 ± 0.057	0.337LysTrp: 0.337 ± 0.019	0.596LysTyr: 0.596 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	13.684LeuAla: 13.684 ± 0.158	0.939LeuCys: 0.939 ± 0.031	6.082LeuAsp: 6.082 ± 0.079	4.997LeuGlu: 4.997 ± 0.081	3.489LeuPhe: 3.489 ± 0.072	8.54LeuGly: 8.54 ± 0.114	1.895LeuHis: 1.895 ± 0.056	5.442LeuIle: 5.442 ± 0.077	3.033LeuLys: 3.033 ± 0.063	8.398LeuLeu: 8.398 ± 0.126	2.611LeuMet: 2.611 ± 0.056	2.53LeuAsn: 2.53 ± 0.058	5.832LeuPro: 5.832 ± 0.085	2.658LeuGln: 2.658 ± 0.057	8.418LeuArg: 8.418 ± 0.109	6.324LeuSer: 6.324 ± 0.08	5.571LeuThr: 5.571 ± 0.086	7.216LeuVal: 7.216 ± 0.103	1.419LeuTrp: 1.419 ± 0.045	1.971LeuTyr: 1.971 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	3.553MetAla: 3.553 ± 0.065	0.169MetCys: 0.169 ± 0.014	1.356MetAsp: 1.356 ± 0.036	1.248MetGlu: 1.248 ± 0.042	0.72MetPhe: 0.72 ± 0.03	2.203MetGly: 2.203 ± 0.058	0.422MetHis: 0.422 ± 0.023	1.58MetIle: 1.58 ± 0.045	0.982MetLys: 0.982 ± 0.033	2.434MetLeu: 2.434 ± 0.052	0.648MetMet: 0.648 ± 0.027	0.796MetAsn: 0.796 ± 0.032	1.54MetPro: 1.54 ± 0.038	0.895MetGln: 0.895 ± 0.029	2.202MetArg: 2.202 ± 0.05	1.482MetSer: 1.482 ± 0.042	1.986MetThr: 1.986 ± 0.046	1.821MetVal: 1.821 ± 0.044	0.247MetTrp: 0.247 ± 0.02	0.305MetTyr: 0.305 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.923AsnAla: 2.923 ± 0.061	0.227AsnCys: 0.227 ± 0.017	1.326AsnAsp: 1.326 ± 0.039	1.112AsnGlu: 1.112 ± 0.033	0.799AsnPhe: 0.799 ± 0.029	2.116AsnGly: 2.116 ± 0.058	0.478AsnHis: 0.478 ± 0.021	1.155AsnIle: 1.155 ± 0.04	0.509AsnLys: 0.509 ± 0.021	2.331AsnLeu: 2.331 ± 0.048	0.547AsnMet: 0.547 ± 0.025	0.527AsnAsn: 0.527 ± 0.026	1.864AsnPro: 1.864 ± 0.042	0.592AsnGln: 0.592 ± 0.025	1.883AsnArg: 1.883 ± 0.05	0.957AsnSer: 0.957 ± 0.033	1.107AsnThr: 1.107 ± 0.034	1.703AsnVal: 1.703 ± 0.048	0.406AsnTrp: 0.406 ± 0.024	0.551AsnTyr: 0.551 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	6.402ProAla: 6.402 ± 0.104	0.398ProCys: 0.398 ± 0.018	4.527ProAsp: 4.527 ± 0.073	4.531ProGlu: 4.531 ± 0.078	1.887ProPhe: 1.887 ± 0.048	5.083ProGly: 5.083 ± 0.075	1.143ProHis: 1.143 ± 0.037	2.507ProIle: 2.507 ± 0.051	1.38ProLys: 1.38 ± 0.051	4.594ProLeu: 4.594 ± 0.078	1.299ProMet: 1.299 ± 0.038	1.232ProAsn: 1.232 ± 0.041	2.638ProPro: 2.638 ± 0.063	1.686ProGln: 1.686 ± 0.043	3.776ProArg: 3.776 ± 0.066	2.399ProSer: 2.399 ± 0.049	2.283ProThr: 2.283 ± 0.056	4.641ProVal: 4.641 ± 0.079	0.781ProTrp: 0.781 ± 0.035	1.112ProTyr: 1.112 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	4.325GlnAla: 4.325 ± 0.078	0.175GlnCys: 0.175 ± 0.015	1.624GlnAsp: 1.624 ± 0.042	1.552GlnGlu: 1.552 ± 0.042	0.917GlnPhe: 0.917 ± 0.035	2.529GlnGly: 2.529 ± 0.057	0.495GlnHis: 0.495 ± 0.023	2.104GlnIle: 2.104 ± 0.046	0.983GlnLys: 0.983 ± 0.037	2.548GlnLeu: 2.548 ± 0.06	1.045GlnMet: 1.045 ± 0.036	0.736GlnAsn: 0.736 ± 0.028	1.777GlnPro: 1.777 ± 0.046	0.941GlnGln: 0.941 ± 0.039	2.252GlnArg: 2.252 ± 0.056	1.523GlnSer: 1.523 ± 0.042	1.632GlnThr: 1.632 ± 0.046	2.226GlnVal: 2.226 ± 0.048	0.365GlnTrp: 0.365 ± 0.02	0.501GlnTyr: 0.501 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	10.58ArgAla: 10.58 ± 0.139	0.52ArgCys: 0.52 ± 0.027	4.902ArgAsp: 4.902 ± 0.075	4.802ArgGlu: 4.802 ± 0.077	2.942ArgPhe: 2.942 ± 0.065	5.568ArgGly: 5.568 ± 0.081	2.03ArgHis: 2.03 ± 0.049	5.159ArgIle: 5.159 ± 0.077	2.526ArgLys: 2.526 ± 0.056	9.347ArgLeu: 9.347 ± 0.107	2.315ArgMet: 2.315 ± 0.057	1.994ArgAsn: 1.994 ± 0.047	4.559ArgPro: 4.559 ± 0.07	2.721ArgGln: 2.721 ± 0.057	7.093ArgArg: 7.093 ± 0.093	3.496ArgSer: 3.496 ± 0.058	3.222ArgThr: 3.222 ± 0.068	5.72ArgVal: 5.72 ± 0.077	1.097ArgTrp: 1.097 ± 0.038	1.571ArgTyr: 1.571 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	5.583SerAla: 5.583 ± 0.076	0.435SerCys: 0.435 ± 0.023	2.99SerAsp: 2.99 ± 0.066	2.431SerGlu: 2.431 ± 0.057	1.895SerPhe: 1.895 ± 0.045	5.081SerGly: 5.081 ± 0.09	0.985SerHis: 0.985 ± 0.034	2.328SerIle: 2.328 ± 0.061	1.123SerLys: 1.123 ± 0.04	4.482SerLeu: 4.482 ± 0.07	1.132SerMet: 1.132 ± 0.036	1.081SerAsn: 1.081 ± 0.036	2.587SerPro: 2.587 ± 0.044	1.403SerGln: 1.403 ± 0.041	3.598SerArg: 3.598 ± 0.063	2.175SerSer: 2.175 ± 0.059	2.125SerThr: 2.125 ± 0.05	3.604SerVal: 3.604 ± 0.061	0.708SerTrp: 0.708 ± 0.026	1.107SerTyr: 1.107 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.614ThrAla: 5.614 ± 0.086	0.461ThrCys: 0.461 ± 0.023	2.918ThrAsp: 2.918 ± 0.061	2.779ThrGlu: 2.779 ± 0.058	1.803ThrPhe: 1.803 ± 0.046	5.147ThrGly: 5.147 ± 0.081	1.001ThrHis: 1.001 ± 0.035	2.823ThrIle: 2.823 ± 0.056	1.035ThrLys: 1.035 ± 0.038	5.309ThrLeu: 5.309 ± 0.079	1.137ThrMet: 1.137 ± 0.033	1.08ThrAsn: 1.08 ± 0.031	3.203ThrPro: 3.203 ± 0.064	1.303ThrGln: 1.303 ± 0.038	3.922ThrArg: 3.922 ± 0.069	2.037ThrSer: 2.037 ± 0.048	2.475ThrThr: 2.475 ± 0.061	3.834ThrVal: 3.834 ± 0.076	0.709ThrTrp: 0.709 ± 0.029	1.079ThrTyr: 1.079 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	9.285ValAla: 9.285 ± 0.129	0.6ValCys: 0.6 ± 0.027	3.915ValAsp: 3.915 ± 0.069	4.79ValGlu: 4.79 ± 0.077	2.638ValPhe: 2.638 ± 0.056	5.198ValGly: 5.198 ± 0.089	1.402ValHis: 1.402 ± 0.045	4.194ValIle: 4.194 ± 0.072	1.87ValLys: 1.87 ± 0.045	7.673ValLeu: 7.673 ± 0.106	2.019ValMet: 2.019 ± 0.046	1.87ValAsn: 1.87 ± 0.046	3.738ValPro: 3.738 ± 0.065	1.965ValGln: 1.965 ± 0.042	5.034ValArg: 5.034 ± 0.082	3.827ValSer: 3.827 ± 0.07	4.573ValThr: 4.573 ± 0.074	5.797ValVal: 5.797 ± 0.1	1.025ValTrp: 1.025 ± 0.04	1.388ValTyr: 1.388 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.552TrpAla: 1.552 ± 0.041	0.129TrpCys: 0.129 ± 0.012	0.739TrpAsp: 0.739 ± 0.033	0.673TrpGlu: 0.673 ± 0.03	0.574TrpPhe: 0.574 ± 0.028	1.035TrpGly: 1.035 ± 0.041	0.346TrpHis: 0.346 ± 0.019	0.803TrpIle: 0.803 ± 0.032	0.464TrpLys: 0.464 ± 0.023	1.778TrpLeu: 1.778 ± 0.049	0.365TrpMet: 0.365 ± 0.022	0.407TrpAsn: 0.407 ± 0.02	0.824TrpPro: 0.824 ± 0.029	0.661TrpGln: 0.661 ± 0.031	1.414TrpArg: 1.414 ± 0.047	0.77TrpSer: 0.77 ± 0.031	0.74TrpThr: 0.74 ± 0.027	0.937TrpVal: 0.937 ± 0.037	0.244TrpTrp: 0.244 ± 0.018	0.287TrpTyr: 0.287 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.283TyrAla: 2.283 ± 0.051	0.223TyrCys: 0.223 ± 0.016	1.48TyrAsp: 1.48 ± 0.041	1.153TyrGlu: 1.153 ± 0.041	0.777TyrPhe: 0.777 ± 0.031	1.992TyrGly: 1.992 ± 0.056	0.507TyrHis: 0.507 ± 0.027	0.777TyrIle: 0.777 ± 0.032	0.479TyrLys: 0.479 ± 0.02	2.18TyrLeu: 2.18 ± 0.055	0.454TyrMet: 0.454 ± 0.023	0.524TyrAsn: 0.524 ± 0.027	1.053TyrPro: 1.053 ± 0.036	0.623TyrGln: 0.623 ± 0.025	1.811TyrArg: 1.811 ± 0.048	1.059TyrSer: 1.059 ± 0.038	0.905TyrThr: 0.905 ± 0.033	1.502TyrVal: 1.502 ± 0.042	0.324TyrTrp: 0.324 ± 0.019	0.517TyrTyr: 0.517 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2911 proteins (916633 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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