Amino acid dipepetide frequency for Desulfatibacillum aliphaticivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.323AlaAla: 10.323 ± 0.126	1.359AlaCys: 1.359 ± 0.034	4.899AlaAsp: 4.899 ± 0.104	5.364AlaGlu: 5.364 ± 0.072	3.899AlaPhe: 3.899 ± 0.059	8.101AlaGly: 8.101 ± 0.225	1.625AlaHis: 1.625 ± 0.032	5.039AlaIle: 5.039 ± 0.066	4.997AlaLys: 4.997 ± 0.068	9.911AlaLeu: 9.911 ± 0.097	3.234AlaMet: 3.234 ± 0.051	2.917AlaAsn: 2.917 ± 0.081	4.033AlaPro: 4.033 ± 0.07	3.451AlaGln: 3.451 ± 0.049	4.783AlaArg: 4.783 ± 0.055	5.486AlaSer: 5.486 ± 0.076	3.556AlaThr: 3.556 ± 0.113	7.09AlaVal: 7.09 ± 0.067	1.197AlaTrp: 1.197 ± 0.031	2.683AlaTyr: 2.683 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	1.087CysAla: 1.087 ± 0.027	0.265CysCys: 0.265 ± 0.014	0.653CysAsp: 0.653 ± 0.022	0.656CysGlu: 0.656 ± 0.02	0.603CysPhe: 0.603 ± 0.022	1.262CysGly: 1.262 ± 0.034	0.347CysHis: 0.347 ± 0.019	0.74CysIle: 0.74 ± 0.021	0.626CysLys: 0.626 ± 0.021	1.338CysLeu: 1.338 ± 0.033	0.38CysMet: 0.38 ± 0.017	0.419CysAsn: 0.419 ± 0.014	0.821CysPro: 0.821 ± 0.027	0.483CysGln: 0.483 ± 0.016	0.739CysArg: 0.739 ± 0.021	0.825CysSer: 0.825 ± 0.025	0.691CysThr: 0.691 ± 0.019	0.86CysVal: 0.86 ± 0.025	0.131CysTrp: 0.131 ± 0.009	0.389CysTyr: 0.389 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.301AspAla: 5.301 ± 0.108	0.697AspCys: 0.697 ± 0.027	3.197AspAsp: 3.197 ± 0.07	3.687AspGlu: 3.687 ± 0.064	2.836AspPhe: 2.836 ± 0.041	4.677AspGly: 4.677 ± 0.112	1.122AspHis: 1.122 ± 0.026	3.673AspIle: 3.673 ± 0.108	3.126AspLys: 3.126 ± 0.052	6.198AspLeu: 6.198 ± 0.07	1.826AspMet: 1.826 ± 0.036	1.949AspAsn: 1.949 ± 0.044	3.218AspPro: 3.218 ± 0.054	2.036AspGln: 2.036 ± 0.035	2.803AspArg: 2.803 ± 0.049	3.236AspSer: 3.236 ± 0.052	2.103AspThr: 2.103 ± 0.065	4.075AspVal: 4.075 ± 0.107	0.805AspTrp: 0.805 ± 0.024	2.09AspTyr: 2.09 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	6.478GluAla: 6.478 ± 0.074	0.67GluCys: 0.67 ± 0.022	3.922GluAsp: 3.922 ± 0.056	5.134GluGlu: 5.134 ± 0.079	2.372GluPhe: 2.372 ± 0.04	4.201GluGly: 4.201 ± 0.055	1.136GluHis: 1.136 ± 0.03	4.478GluIle: 4.478 ± 0.053	5.109GluLys: 5.109 ± 0.089	5.488GluLeu: 5.488 ± 0.072	2.04GluMet: 2.04 ± 0.035	3.036GluAsn: 3.036 ± 0.046	2.426GluPro: 2.426 ± 0.044	2.38GluGln: 2.38 ± 0.043	3.298GluArg: 3.298 ± 0.05	3.555GluSer: 3.555 ± 0.053	3.447GluThr: 3.447 ± 0.041	4.147GluVal: 4.147 ± 0.047	0.721GluTrp: 0.721 ± 0.023	1.901GluTyr: 1.901 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.438PheAla: 3.438 ± 0.054	0.689PheCys: 0.689 ± 0.02	2.533PheAsp: 2.533 ± 0.035	2.42PheGlu: 2.42 ± 0.045	2.272PhePhe: 2.272 ± 0.047	3.218PheGly: 3.218 ± 0.046	0.88PheHis: 0.88 ± 0.023	2.276PheIle: 2.276 ± 0.038	2.05PheLys: 2.05 ± 0.04	4.098PheLeu: 4.098 ± 0.066	1.203PheMet: 1.203 ± 0.028	1.55PheAsn: 1.55 ± 0.029	1.829PhePro: 1.829 ± 0.039	1.36PheGln: 1.36 ± 0.028	1.986PheArg: 1.986 ± 0.04	3.234PheSer: 3.234 ± 0.053	2.373PheThr: 2.373 ± 0.043	2.76PheVal: 2.76 ± 0.043	0.546PheTrp: 0.546 ± 0.017	1.315PheTyr: 1.315 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	7.476GlyAla: 7.476 ± 0.147	1.189GlyCys: 1.189 ± 0.032	4.662GlyAsp: 4.662 ± 0.147	4.73GlyGlu: 4.73 ± 0.063	3.551GlyPhe: 3.551 ± 0.043	6.523GlyGly: 6.523 ± 0.173	1.431GlyHis: 1.431 ± 0.027	4.59GlyIle: 4.59 ± 0.056	4.79GlyLys: 4.79 ± 0.072	7.965GlyLeu: 7.965 ± 0.083	2.659GlyMet: 2.659 ± 0.041	2.588GlyAsn: 2.588 ± 0.107	2.749GlyPro: 2.749 ± 0.051	2.473GlyGln: 2.473 ± 0.041	4.163GlyArg: 4.163 ± 0.064	4.397GlySer: 4.397 ± 0.199	3.797GlyThr: 3.797 ± 0.155	6.263GlyVal: 6.263 ± 0.068	1.019GlyTrp: 1.019 ± 0.028	2.678GlyTyr: 2.678 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	1.559HisAla: 1.559 ± 0.03	0.294HisCys: 0.294 ± 0.013	1.035HisAsp: 1.035 ± 0.023	1.111HisGlu: 1.111 ± 0.028	0.905HisPhe: 0.905 ± 0.026	1.558HisGly: 1.558 ± 0.034	0.444HisHis: 0.444 ± 0.018	1.107HisIle: 1.107 ± 0.025	0.958HisLys: 0.958 ± 0.025	1.774HisLeu: 1.774 ± 0.039	0.534HisMet: 0.534 ± 0.019	0.673HisAsn: 0.673 ± 0.02	1.229HisPro: 1.229 ± 0.033	0.621HisGln: 0.621 ± 0.02	0.939HisArg: 0.939 ± 0.026	1.017HisSer: 1.017 ± 0.025	0.921HisThr: 0.921 ± 0.02	1.276HisVal: 1.276 ± 0.028	0.243HisTrp: 0.243 ± 0.011	0.688HisTyr: 0.688 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	5.414IleAla: 5.414 ± 0.064	0.836IleCys: 0.836 ± 0.025	3.111IleAsp: 3.111 ± 0.095	3.282IleGlu: 3.282 ± 0.044	2.405IlePhe: 2.405 ± 0.035	4.27IleGly: 4.27 ± 0.06	1.263IleHis: 1.263 ± 0.028	3.464IleIle: 3.464 ± 0.047	3.156IleLys: 3.156 ± 0.052	6.12IleLeu: 6.12 ± 0.061	1.652IleMet: 1.652 ± 0.033	2.351IleAsn: 2.351 ± 0.048	3.027IlePro: 3.027 ± 0.05	2.195IleGln: 2.195 ± 0.037	3.229IleArg: 3.229 ± 0.048	3.762IleSer: 3.762 ± 0.045	3.438IleThr: 3.438 ± 0.129	3.973IleVal: 3.973 ± 0.051	0.579IleTrp: 0.579 ± 0.019	1.639IleTyr: 1.639 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	5.873LysAla: 5.873 ± 0.079	0.563LysCys: 0.563 ± 0.019	3.526LysAsp: 3.526 ± 0.057	4.253LysGlu: 4.253 ± 0.073	1.55LysPhe: 1.55 ± 0.038	4.307LysGly: 4.307 ± 0.059	0.955LysHis: 0.955 ± 0.025	3.685LysIle: 3.685 ± 0.061	4.218LysLys: 4.218 ± 0.074	3.972LysLeu: 3.972 ± 0.064	1.69LysMet: 1.69 ± 0.04	2.393LysAsn: 2.393 ± 0.046	2.581LysPro: 2.581 ± 0.046	1.838LysGln: 1.838 ± 0.034	2.798LysArg: 2.798 ± 0.044	3.011LysSer: 3.011 ± 0.045	3.272LysThr: 3.272 ± 0.047	3.757LysVal: 3.757 ± 0.051	0.588LysTrp: 0.588 ± 0.019	1.609LysTyr: 1.609 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	9.894LeuAla: 9.894 ± 0.106	1.424LeuCys: 1.424 ± 0.034	6.133LeuAsp: 6.133 ± 0.063	7.093LeuGlu: 7.093 ± 0.089	4.215LeuPhe: 4.215 ± 0.07	7.415LeuGly: 7.415 ± 0.075	1.736LeuHis: 1.736 ± 0.035	5.278LeuIle: 5.278 ± 0.058	5.391LeuLys: 5.391 ± 0.072	8.545LeuLeu: 8.545 ± 0.104	2.5LeuMet: 2.5 ± 0.044	3.398LeuAsn: 3.398 ± 0.054	4.485LeuPro: 4.485 ± 0.065	2.832LeuGln: 2.832 ± 0.044	4.26LeuArg: 4.26 ± 0.062	6.157LeuSer: 6.157 ± 0.065	5.185LeuThr: 5.185 ± 0.081	6.139LeuVal: 6.139 ± 0.064	1.049LeuTrp: 1.049 ± 0.03	2.582LeuTyr: 2.582 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	3.363MetAla: 3.363 ± 0.054	0.269MetCys: 0.269 ± 0.012	2.161MetAsp: 2.161 ± 0.037	2.553MetGlu: 2.553 ± 0.044	0.963MetPhe: 0.963 ± 0.028	2.634MetGly: 2.634 ± 0.05	0.555MetHis: 0.555 ± 0.018	1.594MetIle: 1.594 ± 0.034	1.718MetLys: 1.718 ± 0.034	2.398MetLeu: 2.398 ± 0.042	0.717MetMet: 0.717 ± 0.023	1.079MetAsn: 1.079 ± 0.024	1.418MetPro: 1.418 ± 0.031	0.963MetGln: 0.963 ± 0.025	1.246MetArg: 1.246 ± 0.027	1.562MetSer: 1.562 ± 0.032	1.59MetThr: 1.59 ± 0.03	2.106MetVal: 2.106 ± 0.04	0.224MetTrp: 0.224 ± 0.011	0.586MetTyr: 0.586 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.334AsnAla: 3.334 ± 0.084	0.49AsnCys: 0.49 ± 0.018	1.728AsnAsp: 1.728 ± 0.041	1.871AsnGlu: 1.871 ± 0.032	1.407AsnPhe: 1.407 ± 0.03	2.976AsnGly: 2.976 ± 0.105	0.665AsnHis: 0.665 ± 0.018	2.346AsnIle: 2.346 ± 0.062	1.812AsnLys: 1.812 ± 0.036	3.8AsnLeu: 3.8 ± 0.051	1.087AsnMet: 1.087 ± 0.024	1.49AsnAsn: 1.49 ± 0.043	2.387AsnPro: 2.387 ± 0.045	1.429AsnGln: 1.429 ± 0.029	1.915AsnArg: 1.915 ± 0.04	1.974AsnSer: 1.974 ± 0.049	1.755AsnThr: 1.755 ± 0.055	2.5AsnVal: 2.5 ± 0.081	0.44AsnTrp: 0.44 ± 0.016	1.093AsnTyr: 1.093 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	4.003ProAla: 4.003 ± 0.05	0.554ProCys: 0.554 ± 0.019	3.319ProAsp: 3.319 ± 0.054	4.164ProGlu: 4.164 ± 0.061	1.971ProPhe: 1.971 ± 0.04	4.066ProGly: 4.066 ± 0.06	0.86ProHis: 0.86 ± 0.025	2.364ProIle: 2.364 ± 0.04	2.459ProLys: 2.459 ± 0.046	4.063ProLeu: 4.063 ± 0.065	1.267ProMet: 1.267 ± 0.03	1.54ProAsn: 1.54 ± 0.028	2.162ProPro: 2.162 ± 0.045	1.589ProGln: 1.589 ± 0.036	1.839ProArg: 1.839 ± 0.036	2.444ProSer: 2.444 ± 0.044	1.81ProThr: 1.81 ± 0.041	3.608ProVal: 3.608 ± 0.054	0.633ProTrp: 0.633 ± 0.025	1.407ProTyr: 1.407 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.117GlnAla: 4.117 ± 0.056	0.451GlnCys: 0.451 ± 0.015	2.11GlnAsp: 2.11 ± 0.039	2.674GlnGlu: 2.674 ± 0.051	1.122GlnPhe: 1.122 ± 0.029	2.868GlnGly: 2.868 ± 0.039	0.475GlnHis: 0.475 ± 0.019	1.895GlnIle: 1.895 ± 0.029	2.053GlnLys: 2.053 ± 0.036	2.475GlnLeu: 2.475 ± 0.044	0.967GlnMet: 0.967 ± 0.028	1.346GlnAsn: 1.346 ± 0.028	1.276GlnPro: 1.276 ± 0.026	1.026GlnGln: 1.026 ± 0.033	1.558GlnArg: 1.558 ± 0.034	1.91GlnSer: 1.91 ± 0.034	1.867GlnThr: 1.867 ± 0.032	2.551GlnVal: 2.551 ± 0.04	0.432GlnTrp: 0.432 ± 0.018	1.004GlnTyr: 1.004 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	3.845ArgAla: 3.845 ± 0.051	0.546ArgCys: 0.546 ± 0.019	2.855ArgAsp: 2.855 ± 0.047	3.765ArgGlu: 3.765 ± 0.06	2.376ArgPhe: 2.376 ± 0.04	2.991ArgGly: 2.991 ± 0.054	1.018ArgHis: 1.018 ± 0.027	3.531ArgIle: 3.531 ± 0.047	3.144ArgLys: 3.144 ± 0.051	5.205ArgLeu: 5.205 ± 0.07	1.549ArgMet: 1.549 ± 0.032	1.766ArgAsn: 1.766 ± 0.03	2.164ArgPro: 2.164 ± 0.041	1.875ArgGln: 1.875 ± 0.034	2.734ArgArg: 2.734 ± 0.048	2.559ArgSer: 2.559 ± 0.045	2.334ArgThr: 2.334 ± 0.041	3.404ArgVal: 3.404 ± 0.052	0.547ArgTrp: 0.547 ± 0.019	1.504ArgTyr: 1.504 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	4.852SerAla: 4.852 ± 0.089	0.717SerCys: 0.717 ± 0.021	3.02SerAsp: 3.02 ± 0.052	3.109SerGlu: 3.109 ± 0.048	2.494SerPhe: 2.494 ± 0.039	5.478SerGly: 5.478 ± 0.143	1.18SerHis: 1.18 ± 0.027	3.514SerIle: 3.514 ± 0.056	2.805SerLys: 2.805 ± 0.046	6.337SerLeu: 6.337 ± 0.068	1.939SerMet: 1.939 ± 0.036	1.896SerAsn: 1.896 ± 0.04	2.88SerPro: 2.88 ± 0.049	2.295SerGln: 2.295 ± 0.037	3.194SerArg: 3.194 ± 0.054	3.461SerSer: 3.461 ± 0.061	2.633SerThr: 2.633 ± 0.052	4.126SerVal: 4.126 ± 0.086	0.715SerTrp: 0.715 ± 0.02	1.647SerTyr: 1.647 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	4.827ThrAla: 4.827 ± 0.151	0.645ThrCys: 0.645 ± 0.02	2.821ThrAsp: 2.821 ± 0.065	2.744ThrGlu: 2.744 ± 0.047	1.81ThrPhe: 1.81 ± 0.036	5.061ThrGly: 5.061 ± 0.159	0.951ThrHis: 0.951 ± 0.022	3.031ThrIle: 3.031 ± 0.083	2.024ThrLys: 2.024 ± 0.035	4.796ThrLeu: 4.796 ± 0.08	1.299ThrMet: 1.299 ± 0.028	1.649ThrAsn: 1.649 ± 0.052	2.76ThrPro: 2.76 ± 0.045	1.64ThrGln: 1.64 ± 0.029	2.251ThrArg: 2.251 ± 0.038	2.639ThrSer: 2.639 ± 0.063	2.45ThrThr: 2.45 ± 0.076	3.843ThrVal: 3.843 ± 0.12	0.619ThrTrp: 0.619 ± 0.02	1.553ThrTyr: 1.553 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	5.3ValAla: 5.3 ± 0.066	1.054ValCys: 1.054 ± 0.026	4.375ValAsp: 4.375 ± 0.102	4.732ValGlu: 4.732 ± 0.057	3.311ValPhe: 3.311 ± 0.05	4.8ValGly: 4.8 ± 0.064	1.361ValHis: 1.361 ± 0.027	4.309ValIle: 4.309 ± 0.057	3.809ValLys: 3.809 ± 0.053	7.154ValLeu: 7.154 ± 0.071	2.056ValMet: 2.056 ± 0.037	2.805ValAsn: 2.805 ± 0.074	2.785ValPro: 2.785 ± 0.048	2.238ValGln: 2.238 ± 0.036	3.754ValArg: 3.754 ± 0.051	4.422ValSer: 4.422 ± 0.064	3.887ValThr: 3.887 ± 0.151	5.154ValVal: 5.154 ± 0.071	0.816ValTrp: 0.816 ± 0.025	2.177ValTyr: 2.177 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.052TrpAla: 1.052 ± 0.021	0.151TrpCys: 0.151 ± 0.008	0.742TrpAsp: 0.742 ± 0.025	0.803TrpGlu: 0.803 ± 0.025	0.502TrpPhe: 0.502 ± 0.016	0.932TrpGly: 0.932 ± 0.027	0.224TrpHis: 0.224 ± 0.011	0.735TrpIle: 0.735 ± 0.022	0.714TrpLys: 0.714 ± 0.018	1.155TrpLeu: 1.155 ± 0.026	0.355TrpMet: 0.355 ± 0.015	0.483TrpAsn: 0.483 ± 0.018	0.464TrpPro: 0.464 ± 0.015	0.392TrpGln: 0.392 ± 0.015	0.635TrpArg: 0.635 ± 0.019	0.646TrpSer: 0.646 ± 0.021	0.672TrpThr: 0.672 ± 0.02	0.793TrpVal: 0.793 ± 0.022	0.165TrpTrp: 0.165 ± 0.011	0.325TrpTyr: 0.325 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.414TyrAla: 2.414 ± 0.035	0.452TyrCys: 0.452 ± 0.017	1.854TyrAsp: 1.854 ± 0.05	1.793TyrGlu: 1.793 ± 0.034	1.464TyrPhe: 1.464 ± 0.032	2.355TyrGly: 2.355 ± 0.045	0.659TyrHis: 0.659 ± 0.018	1.519TyrIle: 1.519 ± 0.034	1.482TyrLys: 1.482 ± 0.037	2.919TyrLeu: 2.919 ± 0.045	0.744TyrMet: 0.744 ± 0.021	1.17TyrAsn: 1.17 ± 0.032	1.426TyrPro: 1.426 ± 0.032	1.06TyrGln: 1.06 ± 0.023	1.589TyrArg: 1.589 ± 0.034	1.995TyrSer: 1.995 ± 0.04	1.633TyrThr: 1.633 ± 0.045	1.875TyrVal: 1.875 ± 0.031	0.471TyrTrp: 0.471 ± 0.02	1.199TyrTyr: 1.199 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5198 proteins (1868736 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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