Amino acid dipepetide frequency for Jiangella asiatica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.403AlaAla: 21.403 ± 0.132	0.912AlaCys: 0.912 ± 0.022	9.034AlaAsp: 9.034 ± 0.08	8.173AlaGlu: 8.173 ± 0.068	3.52AlaPhe: 3.52 ± 0.047	13.908AlaGly: 13.908 ± 0.112	2.419AlaHis: 2.419 ± 0.036	4.267AlaIle: 4.267 ± 0.052	1.741AlaLys: 1.741 ± 0.037	12.997AlaLeu: 12.997 ± 0.103	2.628AlaMet: 2.628 ± 0.039	2.026AlaAsn: 2.026 ± 0.03	6.271AlaPro: 6.271 ± 0.059	3.301AlaGln: 3.301 ± 0.039	9.861AlaArg: 9.861 ± 0.084	6.142AlaSer: 6.142 ± 0.061	7.649AlaThr: 7.649 ± 0.073	12.77AlaVal: 12.77 ± 0.113	1.994AlaTrp: 1.994 ± 0.032	2.55AlaTyr: 2.55 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	0.84CysAla: 0.84 ± 0.022	0.094CysCys: 0.094 ± 0.007	0.465CysAsp: 0.465 ± 0.014	0.351CysGlu: 0.351 ± 0.012	0.187CysPhe: 0.187 ± 0.009	0.855CysGly: 0.855 ± 0.023	0.211CysHis: 0.211 ± 0.011	0.166CysIle: 0.166 ± 0.009	0.061CysLys: 0.061 ± 0.006	0.576CysLeu: 0.576 ± 0.017	0.105CysMet: 0.105 ± 0.007	0.123CysAsn: 0.123 ± 0.008	0.411CysPro: 0.411 ± 0.016	0.164CysGln: 0.164 ± 0.009	0.537CysArg: 0.537 ± 0.017	0.382CysSer: 0.382 ± 0.016	0.423CysThr: 0.423 ± 0.016	0.601CysVal: 0.601 ± 0.017	0.124CysTrp: 0.124 ± 0.008	0.147CysTyr: 0.147 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	8.423AspAla: 8.423 ± 0.073	0.34AspCys: 0.34 ± 0.013	5.523AspAsp: 5.523 ± 0.061	4.564AspGlu: 4.564 ± 0.05	1.535AspPhe: 1.535 ± 0.026	7.964AspGly: 7.964 ± 0.086	1.572AspHis: 1.572 ± 0.029	2.015AspIle: 2.015 ± 0.033	0.68AspLys: 0.68 ± 0.02	6.798AspLeu: 6.798 ± 0.06	0.741AspMet: 0.741 ± 0.019	1.042AspAsn: 1.042 ± 0.028	4.942AspPro: 4.942 ± 0.057	1.838AspGln: 1.838 ± 0.034	5.093AspArg: 5.093 ± 0.055	2.413AspSer: 2.413 ± 0.04	3.316AspThr: 3.316 ± 0.045	6.396AspVal: 6.396 ± 0.057	1.033AspTrp: 1.033 ± 0.024	1.315AspTyr: 1.315 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	6.849GluAla: 6.849 ± 0.066	0.323GluCys: 0.323 ± 0.013	2.63GluAsp: 2.63 ± 0.042	2.763GluGlu: 2.763 ± 0.049	1.654GluPhe: 1.654 ± 0.03	3.578GluGly: 3.578 ± 0.043	1.657GluHis: 1.657 ± 0.029	2.298GluIle: 2.298 ± 0.033	0.89GluLys: 0.89 ± 0.025	7.108GluLeu: 7.108 ± 0.058	0.851GluMet: 0.851 ± 0.019	1.086GluAsn: 1.086 ± 0.023	3.901GluPro: 3.901 ± 0.051	2.12GluGln: 2.12 ± 0.029	5.358GluArg: 5.358 ± 0.059	2.69GluSer: 2.69 ± 0.034	2.921GluThr: 2.921 ± 0.035	5.003GluVal: 5.003 ± 0.063	0.84GluTrp: 0.84 ± 0.021	1.188GluTyr: 1.188 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	3.807PheAla: 3.807 ± 0.047	0.24PheCys: 0.24 ± 0.01	2.342PheAsp: 2.342 ± 0.034	1.605PheGlu: 1.605 ± 0.026	0.874PhePhe: 0.874 ± 0.023	3.019PheGly: 3.019 ± 0.05	0.602PheHis: 0.602 ± 0.016	0.858PheIle: 0.858 ± 0.025	0.324PheLys: 0.324 ± 0.013	2.528PheLeu: 2.528 ± 0.039	0.436PheMet: 0.436 ± 0.014	0.583PheAsn: 0.583 ± 0.02	1.364PhePro: 1.364 ± 0.025	0.72PheGln: 0.72 ± 0.02	1.839PheArg: 1.839 ± 0.029	1.415PheSer: 1.415 ± 0.031	1.928PheThr: 1.928 ± 0.031	2.694PheVal: 2.694 ± 0.041	0.438PheTrp: 0.438 ± 0.017	0.639PheTyr: 0.639 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	10.863GlyAla: 10.863 ± 0.089	0.811GlyCys: 0.811 ± 0.02	5.971GlyAsp: 5.971 ± 0.061	5.229GlyGlu: 5.229 ± 0.056	2.937GlyPhe: 2.937 ± 0.042	8.534GlyGly: 8.534 ± 0.088	2.153GlyHis: 2.153 ± 0.04	3.628GlyIle: 3.628 ± 0.043	1.473GlyLys: 1.473 ± 0.031	9.453GlyLeu: 9.453 ± 0.082	1.974GlyMet: 1.974 ± 0.028	1.679GlyAsn: 1.679 ± 0.032	4.915GlyPro: 4.915 ± 0.055	2.609GlyGln: 2.609 ± 0.031	7.772GlyArg: 7.772 ± 0.068	5.326GlySer: 5.326 ± 0.054	5.865GlyThr: 5.865 ± 0.067	8.288GlyVal: 8.288 ± 0.064	1.903GlyTrp: 1.903 ± 0.031	2.368GlyTyr: 2.368 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	2.514HisAla: 2.514 ± 0.046	0.167HisCys: 0.167 ± 0.009	1.652HisAsp: 1.652 ± 0.027	1.235HisGlu: 1.235 ± 0.027	0.551HisPhe: 0.551 ± 0.017	2.28HisGly: 2.28 ± 0.036	0.667HisHis: 0.667 ± 0.019	0.593HisIle: 0.593 ± 0.016	0.221HisLys: 0.221 ± 0.01	2.283HisLeu: 2.283 ± 0.04	0.262HisMet: 0.262 ± 0.01	0.362HisAsn: 0.362 ± 0.014	1.63HisPro: 1.63 ± 0.028	0.612HisGln: 0.612 ± 0.017	1.94HisArg: 1.94 ± 0.035	0.872HisSer: 0.872 ± 0.019	1.11HisThr: 1.11 ± 0.028	1.968HisVal: 1.968 ± 0.034	0.379HisTrp: 0.379 ± 0.015	0.496HisTyr: 0.496 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	4.978IleAla: 4.978 ± 0.052	0.255IleCys: 0.255 ± 0.01	2.797IleAsp: 2.797 ± 0.037	2.304IleGlu: 2.304 ± 0.034	0.905IlePhe: 0.905 ± 0.023	3.732IleGly: 3.732 ± 0.042	0.614IleHis: 0.614 ± 0.018	1.112IleIle: 1.112 ± 0.027	0.491IleLys: 0.491 ± 0.015	2.606IleLeu: 2.606 ± 0.043	0.56IleMet: 0.56 ± 0.016	0.687IleAsn: 0.687 ± 0.018	1.883IlePro: 1.883 ± 0.033	0.757IleGln: 0.757 ± 0.02	2.318IleArg: 2.318 ± 0.03	1.706IleSer: 1.706 ± 0.025	2.226IleThr: 2.226 ± 0.033	3.517IleVal: 3.517 ± 0.044	0.449IleTrp: 0.449 ± 0.015	0.694IleTyr: 0.694 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	1.691LysAla: 1.691 ± 0.033	0.059LysCys: 0.059 ± 0.005	0.71LysAsp: 0.71 ± 0.021	0.622LysGlu: 0.622 ± 0.018	0.314LysPhe: 0.314 ± 0.013	1.013LysGly: 1.013 ± 0.024	0.312LysHis: 0.312 ± 0.012	0.59LysIle: 0.59 ± 0.019	0.328LysLys: 0.328 ± 0.019	1.36LysLeu: 1.36 ± 0.025	0.225LysMet: 0.225 ± 0.01	0.291LysAsn: 0.291 ± 0.012	0.873LysPro: 0.873 ± 0.023	0.439LysGln: 0.439 ± 0.016	1.065LysArg: 1.065 ± 0.025	0.738LysSer: 0.738 ± 0.022	0.839LysThr: 0.839 ± 0.026	1.235LysVal: 1.235 ± 0.027	0.175LysTrp: 0.175 ± 0.008	0.287LysTyr: 0.287 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	15.228LeuAla: 15.228 ± 0.121	0.637LeuCys: 0.637 ± 0.018	7.295LeuAsp: 7.295 ± 0.062	4.875LeuGlu: 4.875 ± 0.053	2.598LeuPhe: 2.598 ± 0.04	9.19LeuGly: 9.19 ± 0.069	1.968LeuHis: 1.968 ± 0.034	3.343LeuIle: 3.343 ± 0.044	1.159LeuLys: 1.159 ± 0.025	10.066LeuLeu: 10.066 ± 0.096	1.624LeuMet: 1.624 ± 0.027	1.62LeuAsn: 1.62 ± 0.026	5.995LeuPro: 5.995 ± 0.06	2.056LeuGln: 2.056 ± 0.034	8.361LeuArg: 8.361 ± 0.068	5.285LeuSer: 5.285 ± 0.05	6.456LeuThr: 6.456 ± 0.056	9.59LeuVal: 9.59 ± 0.08	1.221LeuTrp: 1.221 ± 0.023	1.779LeuTyr: 1.779 ± 0.03	0.0LeuXaa: 0.0 ± 0.0
Met	2.206MetAla: 2.206 ± 0.037	0.116MetCys: 0.116 ± 0.007	0.844MetAsp: 0.844 ± 0.019	0.666MetGlu: 0.666 ± 0.016	0.499MetPhe: 0.499 ± 0.015	1.22MetGly: 1.22 ± 0.027	0.338MetHis: 0.338 ± 0.012	0.783MetIle: 0.783 ± 0.018	0.313MetLys: 0.313 ± 0.013	1.805MetLeu: 1.805 ± 0.027	0.324MetMet: 0.324 ± 0.013	0.425MetAsn: 0.425 ± 0.016	1.109MetPro: 1.109 ± 0.024	0.386MetGln: 0.386 ± 0.013	1.49MetArg: 1.49 ± 0.026	1.339MetSer: 1.339 ± 0.023	1.65MetThr: 1.65 ± 0.027	1.482MetVal: 1.482 ± 0.027	0.234MetTrp: 0.234 ± 0.01	0.348MetTyr: 0.348 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.104AsnAla: 2.104 ± 0.036	0.125AsnCys: 0.125 ± 0.008	1.132AsnAsp: 1.132 ± 0.024	0.882AsnGlu: 0.882 ± 0.022	0.486AsnPhe: 0.486 ± 0.017	1.809AsnGly: 1.809 ± 0.034	0.415AsnHis: 0.415 ± 0.015	0.662AsnIle: 0.662 ± 0.02	0.228AsnLys: 0.228 ± 0.011	1.763AsnLeu: 1.763 ± 0.031	0.24AsnMet: 0.24 ± 0.01	0.397AsnAsn: 0.397 ± 0.016	1.444AsnPro: 1.444 ± 0.026	0.546AsnGln: 0.546 ± 0.017	1.266AsnArg: 1.266 ± 0.026	0.847AsnSer: 0.847 ± 0.019	1.058AsnThr: 1.058 ± 0.024	1.614AsnVal: 1.614 ± 0.032	0.279AsnTrp: 0.279 ± 0.012	0.447AsnTyr: 0.447 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	8.269ProAla: 8.269 ± 0.074	0.292ProCys: 0.292 ± 0.013	4.909ProAsp: 4.909 ± 0.053	3.886ProGlu: 3.886 ± 0.048	1.656ProPhe: 1.656 ± 0.031	6.206ProGly: 6.206 ± 0.065	1.24ProHis: 1.24 ± 0.028	1.704ProIle: 1.704 ± 0.027	0.726ProLys: 0.726 ± 0.019	5.007ProLeu: 5.007 ± 0.052	1.111ProMet: 1.111 ± 0.021	1.087ProAsn: 1.087 ± 0.024	3.519ProPro: 3.519 ± 0.049	1.337ProGln: 1.337 ± 0.028	3.822ProArg: 3.822 ± 0.041	3.337ProSer: 3.337 ± 0.041	3.464ProThr: 3.464 ± 0.054	5.44ProVal: 5.44 ± 0.047	0.975ProTrp: 0.975 ± 0.023	1.294ProTyr: 1.294 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	3.486GlnAla: 3.486 ± 0.039	0.141GlnCys: 0.141 ± 0.008	1.243GlnAsp: 1.243 ± 0.025	1.221GlnGlu: 1.221 ± 0.025	0.755GlnPhe: 0.755 ± 0.022	1.816GlnGly: 1.816 ± 0.03	0.665GlnHis: 0.665 ± 0.019	1.103GlnIle: 1.103 ± 0.025	0.335GlnLys: 0.335 ± 0.013	3.174GlnLeu: 3.174 ± 0.043	0.411GlnMet: 0.411 ± 0.015	0.491GlnAsn: 0.491 ± 0.014	1.778GlnPro: 1.778 ± 0.031	0.987GlnGln: 0.987 ± 0.022	2.428GlnArg: 2.428 ± 0.039	1.178GlnSer: 1.178 ± 0.025	1.317GlnThr: 1.317 ± 0.025	2.581GlnVal: 2.581 ± 0.039	0.447GlnTrp: 0.447 ± 0.015	0.579GlnTyr: 0.579 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	9.286ArgAla: 9.286 ± 0.08	0.575ArgCys: 0.575 ± 0.017	4.787ArgAsp: 4.787 ± 0.049	4.31ArgGlu: 4.31 ± 0.051	2.484ArgPhe: 2.484 ± 0.034	5.752ArgGly: 5.752 ± 0.058	2.041ArgHis: 2.041 ± 0.033	3.042ArgIle: 3.042 ± 0.041	1.08ArgLys: 1.08 ± 0.024	8.634ArgLeu: 8.634 ± 0.077	1.706ArgMet: 1.706 ± 0.031	1.299ArgAsn: 1.299 ± 0.027	4.917ArgPro: 4.917 ± 0.058	2.34ArgGln: 2.34 ± 0.036	8.351ArgArg: 8.351 ± 0.091	4.305ArgSer: 4.305 ± 0.046	4.802ArgThr: 4.802 ± 0.054	6.352ArgVal: 6.352 ± 0.063	1.586ArgTrp: 1.586 ± 0.031	1.904ArgTyr: 1.904 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.476SerAla: 6.476 ± 0.055	0.387SerCys: 0.387 ± 0.014	3.013SerAsp: 3.013 ± 0.042	2.343SerGlu: 2.343 ± 0.035	1.636SerPhe: 1.636 ± 0.03	5.678SerGly: 5.678 ± 0.056	0.972SerHis: 0.972 ± 0.024	1.865SerIle: 1.865 ± 0.027	0.687SerLys: 0.687 ± 0.021	4.807SerLeu: 4.807 ± 0.049	1.168SerMet: 1.168 ± 0.024	0.875SerAsn: 0.875 ± 0.026	3.103SerPro: 3.103 ± 0.039	1.257SerGln: 1.257 ± 0.023	3.799SerArg: 3.799 ± 0.044	3.031SerSer: 3.031 ± 0.038	3.338SerThr: 3.338 ± 0.045	4.599SerVal: 4.599 ± 0.045	1.065SerTrp: 1.065 ± 0.022	1.216SerTyr: 1.216 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	8.117ThrAla: 8.117 ± 0.069	0.385ThrCys: 0.385 ± 0.014	3.803ThrAsp: 3.803 ± 0.056	3.128ThrGlu: 3.128 ± 0.044	1.906ThrPhe: 1.906 ± 0.031	6.261ThrGly: 6.261 ± 0.063	1.147ThrHis: 1.147 ± 0.025	2.235ThrIle: 2.235 ± 0.033	0.808ThrLys: 0.808 ± 0.021	5.715ThrLeu: 5.715 ± 0.056	1.174ThrMet: 1.174 ± 0.025	1.071ThrAsn: 1.071 ± 0.029	3.774ThrPro: 3.774 ± 0.045	1.338ThrGln: 1.338 ± 0.025	3.775ThrArg: 3.775 ± 0.041	3.363ThrSer: 3.363 ± 0.045	4.103ThrThr: 4.103 ± 0.05	6.56ThrVal: 6.56 ± 0.07	1.085ThrTrp: 1.085 ± 0.024	1.402ThrTyr: 1.402 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	12.754ValAla: 12.754 ± 0.096	0.661ValCys: 0.661 ± 0.019	6.783ValAsp: 6.783 ± 0.062	5.51ValGlu: 5.51 ± 0.057	2.56ValPhe: 2.56 ± 0.037	7.789ValGly: 7.789 ± 0.06	1.921ValHis: 1.921 ± 0.032	3.236ValIle: 3.236 ± 0.044	1.134ValLys: 1.134 ± 0.026	9.631ValLeu: 9.631 ± 0.083	1.475ValMet: 1.475 ± 0.026	1.718ValAsn: 1.718 ± 0.03	5.371ValPro: 5.371 ± 0.052	2.095ValGln: 2.095 ± 0.032	7.141ValArg: 7.141 ± 0.056	4.885ValSer: 4.885 ± 0.046	6.398ValThr: 6.398 ± 0.075	10.453ValVal: 10.453 ± 0.092	1.166ValTrp: 1.166 ± 0.027	1.648ValTyr: 1.648 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.688TrpAla: 1.688 ± 0.03	0.146TrpCys: 0.146 ± 0.008	0.957TrpAsp: 0.957 ± 0.023	0.775TrpGlu: 0.775 ± 0.019	0.545TrpPhe: 0.545 ± 0.016	1.092TrpGly: 1.092 ± 0.023	0.423TrpHis: 0.423 ± 0.014	0.561TrpIle: 0.561 ± 0.015	0.255TrpLys: 0.255 ± 0.011	1.845TrpLeu: 1.845 ± 0.033	0.327TrpMet: 0.327 ± 0.012	0.468TrpAsn: 0.468 ± 0.018	0.929TrpPro: 0.929 ± 0.02	0.604TrpGln: 0.604 ± 0.016	1.43TrpArg: 1.43 ± 0.028	1.066TrpSer: 1.066 ± 0.023	1.077TrpThr: 1.077 ± 0.023	1.214TrpVal: 1.214 ± 0.024	0.377TrpTrp: 0.377 ± 0.013	0.383TrpTyr: 0.383 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.587TyrAla: 2.587 ± 0.036	0.156TyrCys: 0.156 ± 0.01	1.652TyrAsp: 1.652 ± 0.028	1.265TyrGlu: 1.265 ± 0.025	0.654TyrPhe: 0.654 ± 0.02	2.053TyrGly: 2.053 ± 0.028	0.455TyrHis: 0.455 ± 0.015	0.532TyrIle: 0.532 ± 0.015	0.231TyrLys: 0.231 ± 0.01	2.192TyrLeu: 2.192 ± 0.032	0.235TyrMet: 0.235 ± 0.011	0.414TyrAsn: 0.414 ± 0.015	1.151TyrPro: 1.151 ± 0.024	0.629TyrGln: 0.629 ± 0.018	1.907TyrArg: 1.907 ± 0.033	0.997TyrSer: 0.997 ± 0.02	1.208TyrThr: 1.208 ± 0.024	1.973TyrVal: 1.973 ± 0.03	0.393TyrTrp: 0.393 ± 0.014	0.521TyrTyr: 0.521 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6206 proteins (2091672 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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