Amino acid dipepetide frequency for Digitaria streak virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.833AlaAla: 7.833 ± 2.782
0.0AlaCys: 0.0 ± 0.0
5.222AlaAsp: 5.222 ± 2.816
5.222AlaGlu: 5.222 ± 2.767
1.305AlaPhe: 1.305 ± 1.103
2.611AlaGly: 2.611 ± 2.205
0.0AlaHis: 0.0 ± 0.0
3.916AlaIle: 3.916 ± 1.243
2.611AlaLys: 2.611 ± 0.927
6.527AlaLeu: 6.527 ± 1.628
1.305AlaMet: 1.305 ± 0.892
5.222AlaAsn: 5.222 ± 1.34
5.222AlaPro: 5.222 ± 0.94
5.222AlaGln: 5.222 ± 2.505
1.305AlaArg: 1.305 ± 1.336
7.833AlaSer: 7.833 ± 5.273
7.833AlaThr: 7.833 ± 0.384
6.527AlaVal: 6.527 ± 3.67
0.0AlaTrp: 0.0 ± 0.0
2.611AlaTyr: 2.611 ± 0.927
0.0AlaXaa: 0.0 ± 0.0
Cys
1.305CysAla: 1.305 ± 1.103
0.0CysCys: 0.0 ± 0.0
1.305CysAsp: 1.305 ± 0.982
0.0CysGlu: 0.0 ± 0.0
1.305CysPhe: 1.305 ± 1.103
0.0CysGly: 0.0 ± 0.0
2.611CysHis: 2.611 ± 2.205
1.305CysIle: 1.305 ± 1.468
1.305CysLys: 1.305 ± 1.103
2.611CysLeu: 2.611 ± 1.467
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.305CysPro: 1.305 ± 1.336
2.611CysGln: 2.611 ± 1.474
1.305CysArg: 1.305 ± 1.103
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.305CysTrp: 1.305 ± 1.336
1.305CysTyr: 1.305 ± 0.982
0.0CysXaa: 0.0 ± 0.0
Asp
2.611AspAla: 2.611 ± 1.317
0.0AspCys: 0.0 ± 0.0
3.916AspAsp: 3.916 ± 2.636
3.916AspGlu: 3.916 ± 2.414
1.305AspPhe: 1.305 ± 1.103
3.916AspGly: 3.916 ± 0.895
3.916AspHis: 3.916 ± 2.946
5.222AspIle: 5.222 ± 1.34
1.305AspLys: 1.305 ± 1.103
6.527AspLeu: 6.527 ± 3.703
1.305AspMet: 1.305 ± 1.336
0.0AspAsn: 0.0 ± 0.0
1.305AspPro: 1.305 ± 1.468
0.0AspGln: 0.0 ± 0.0
2.611AspArg: 2.611 ± 0.927
0.0AspSer: 0.0 ± 0.0
2.611AspThr: 2.611 ± 1.694
1.305AspVal: 1.305 ± 0.982
5.222AspTrp: 5.222 ± 2.947
2.611AspTyr: 2.611 ± 0.927
0.0AspXaa: 0.0 ± 0.0
Glu
7.833GluAla: 7.833 ± 4.236
0.0GluCys: 0.0 ± 0.0
1.305GluAsp: 1.305 ± 1.336
5.222GluGlu: 5.222 ± 2.026
2.611GluPhe: 2.611 ± 1.467
5.222GluGly: 5.222 ± 2.634
1.305GluHis: 1.305 ± 0.982
1.305GluIle: 1.305 ± 1.468
3.916GluLys: 3.916 ± 2.946
2.611GluLeu: 2.611 ± 1.467
0.0GluMet: 0.0 ± 0.0
1.305GluAsn: 1.305 ± 0.982
1.305GluPro: 1.305 ± 0.982
0.0GluGln: 0.0 ± 0.0
2.611GluArg: 2.611 ± 1.474
3.916GluSer: 3.916 ± 2.019
5.222GluThr: 5.222 ± 1.835
2.611GluVal: 2.611 ± 1.694
2.611GluTrp: 2.611 ± 1.694
3.916GluTyr: 3.916 ± 2.118
0.0GluXaa: 0.0 ± 0.0
Phe
1.305PheAla: 1.305 ± 1.103
1.305PheCys: 1.305 ± 1.336
2.611PheAsp: 2.611 ± 0.927
3.916PheGlu: 3.916 ± 2.118
2.611PhePhe: 2.611 ± 1.474
2.611PheGly: 2.611 ± 1.694
2.611PheHis: 2.611 ± 0.927
1.305PheIle: 1.305 ± 0.982
2.611PheLys: 2.611 ± 1.317
2.611PheLeu: 2.611 ± 1.964
0.0PheMet: 0.0 ± 0.0
1.305PheAsn: 1.305 ± 1.336
3.916PhePro: 3.916 ± 1.785
1.305PheGln: 1.305 ± 0.982
1.305PheArg: 1.305 ± 0.982
2.611PheSer: 2.611 ± 1.317
3.916PheThr: 3.916 ± 3.308
6.527PheVal: 6.527 ± 2.761
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.916GlyAla: 3.916 ± 2.452
1.305GlyCys: 1.305 ± 1.336
1.305GlyAsp: 1.305 ± 1.103
5.222GlyGlu: 5.222 ± 0.94
0.0GlyPhe: 0.0 ± 0.0
2.611GlyGly: 2.611 ± 2.205
0.0GlyHis: 0.0 ± 0.0
1.305GlyIle: 1.305 ± 1.103
2.611GlyLys: 2.611 ± 2.673
2.611GlyLeu: 2.611 ± 1.317
0.0GlyMet: 0.0 ± 0.0
2.611GlyAsn: 2.611 ± 1.694
6.527GlyPro: 6.527 ± 1.948
1.305GlyGln: 1.305 ± 1.103
6.527GlyArg: 6.527 ± 2.995
10.444GlySer: 10.444 ± 5.637
2.611GlyThr: 2.611 ± 0.927
7.833GlyVal: 7.833 ± 5.084
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
3.916HisAla: 3.916 ± 2.946
0.0HisCys: 0.0 ± 0.0
1.305HisAsp: 1.305 ± 1.103
0.0HisGlu: 0.0 ± 0.0
1.305HisPhe: 1.305 ± 1.103
0.0HisGly: 0.0 ± 0.0
1.305HisHis: 1.305 ± 0.982
0.0HisIle: 0.0 ± 0.0
1.305HisLys: 1.305 ± 1.103
3.916HisLeu: 3.916 ± 1.243
0.0HisMet: 0.0 ± 0.0
2.611HisAsn: 2.611 ± 1.474
2.611HisPro: 2.611 ± 1.964
0.0HisGln: 0.0 ± 0.0
3.916HisArg: 3.916 ± 1.243
2.611HisSer: 2.611 ± 1.964
1.305HisThr: 1.305 ± 1.103
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.222IleAla: 5.222 ± 1.835
0.0IleCys: 0.0 ± 0.0
3.916IleAsp: 3.916 ± 0.895
0.0IleGlu: 0.0 ± 0.0
2.611IlePhe: 2.611 ± 1.694
3.916IleGly: 3.916 ± 2.029
0.0IleHis: 0.0 ± 0.0
2.611IleIle: 2.611 ± 1.474
1.305IleLys: 1.305 ± 1.103
7.833IleLeu: 7.833 ± 3.225
0.0IleMet: 0.0 ± 0.0
1.305IleAsn: 1.305 ± 0.982
2.611IlePro: 2.611 ± 2.673
2.611IleGln: 2.611 ± 0.927
1.305IleArg: 1.305 ± 1.103
1.305IleSer: 1.305 ± 0.982
1.305IleThr: 1.305 ± 0.982
0.0IleVal: 0.0 ± 0.0
1.305IleTrp: 1.305 ± 1.468
5.222IleTyr: 5.222 ± 0.94
0.0IleXaa: 0.0 ± 0.0
Lys
2.611LysAla: 2.611 ± 0.927
1.305LysCys: 1.305 ± 0.982
2.611LysAsp: 2.611 ± 1.474
2.611LysGlu: 2.611 ± 1.474
3.916LysPhe: 3.916 ± 0.895
2.611LysGly: 2.611 ± 2.205
1.305LysHis: 1.305 ± 0.982
0.0LysIle: 0.0 ± 0.0
7.833LysLys: 7.833 ± 2.516
1.305LysLeu: 1.305 ± 0.982
1.305LysMet: 1.305 ± 1.336
2.611LysAsn: 2.611 ± 0.927
2.611LysPro: 2.611 ± 1.694
2.611LysGln: 2.611 ± 1.474
7.833LysArg: 7.833 ± 4.057
9.138LysSer: 9.138 ± 2.057
1.305LysThr: 1.305 ± 1.103
2.611LysVal: 2.611 ± 0.927
0.0LysTrp: 0.0 ± 0.0
1.305LysTyr: 1.305 ± 1.336
0.0LysXaa: 0.0 ± 0.0
Leu
3.916LeuAla: 3.916 ± 3.034
2.611LeuCys: 2.611 ± 1.467
1.305LeuAsp: 1.305 ± 1.336
3.916LeuGlu: 3.916 ± 2.019
3.916LeuPhe: 3.916 ± 1.56
7.833LeuGly: 7.833 ± 1.801
2.611LeuHis: 2.611 ± 1.467
3.916LeuIle: 3.916 ± 1.661
2.611LeuLys: 2.611 ± 1.964
9.138LeuLeu: 9.138 ± 3.351
0.0LeuMet: 0.0 ± 0.0
1.305LeuAsn: 1.305 ± 0.982
3.916LeuPro: 3.916 ± 2.766
5.222LeuGln: 5.222 ± 1.855
1.305LeuArg: 1.305 ± 1.468
5.222LeuSer: 5.222 ± 1.34
3.916LeuThr: 3.916 ± 1.661
3.916LeuVal: 3.916 ± 1.56
2.611LeuTrp: 2.611 ± 0.927
3.916LeuTyr: 3.916 ± 1.669
0.0LeuXaa: 0.0 ± 0.0
Met
1.305MetAla: 1.305 ± 0.982
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.611MetGlu: 2.611 ± 1.694
0.0MetPhe: 0.0 ± 0.0
1.305MetGly: 1.305 ± 0.982
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.611MetLys: 2.611 ± 1.317
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.305MetArg: 1.305 ± 0.982
2.611MetSer: 2.611 ± 0.927
2.611MetThr: 2.611 ± 2.673
1.305MetVal: 1.305 ± 0.982
0.0MetTrp: 0.0 ± 0.0
1.305MetTyr: 1.305 ± 1.103
0.0MetXaa: 0.0 ± 0.0
Asn
5.222AsnAla: 5.222 ± 1.855
0.0AsnCys: 0.0 ± 0.0
1.305AsnAsp: 1.305 ± 0.982
1.305AsnGlu: 1.305 ± 1.103
0.0AsnPhe: 0.0 ± 0.0
1.305AsnGly: 1.305 ± 1.103
0.0AsnHis: 0.0 ± 0.0
1.305AsnIle: 1.305 ± 0.982
2.611AsnLys: 2.611 ± 1.964
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
1.305AsnAsn: 1.305 ± 1.336
7.833AsnPro: 7.833 ± 4.236
3.916AsnGln: 3.916 ± 1.243
2.611AsnArg: 2.611 ± 1.467
0.0AsnSer: 0.0 ± 0.0
5.222AsnThr: 5.222 ± 1.34
2.611AsnVal: 2.611 ± 2.673
0.0AsnTrp: 0.0 ± 0.0
1.305AsnTyr: 1.305 ± 1.336
0.0AsnXaa: 0.0 ± 0.0
Pro
9.138ProAla: 9.138 ± 4.043
5.222ProCys: 5.222 ± 2.16
2.611ProAsp: 2.611 ± 1.474
1.305ProGlu: 1.305 ± 0.982
3.916ProPhe: 3.916 ± 2.118
1.305ProGly: 1.305 ± 1.103
2.611ProHis: 2.611 ± 0.927
1.305ProIle: 1.305 ± 0.982
1.305ProLys: 1.305 ± 1.336
0.0ProLeu: 0.0 ± 0.0
0.0ProMet: 0.0 ± 0.0
1.305ProAsn: 1.305 ± 0.982
5.222ProPro: 5.222 ± 1.835
2.611ProGln: 2.611 ± 1.467
2.611ProArg: 2.611 ± 1.467
7.833ProSer: 7.833 ± 2.309
5.222ProThr: 5.222 ± 0.94
2.611ProVal: 2.611 ± 1.964
1.305ProTrp: 1.305 ± 1.468
2.611ProTyr: 2.611 ± 0.927
0.0ProXaa: 0.0 ± 0.0
Gln
1.305GlnAla: 1.305 ± 1.468
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
2.611GlnGlu: 2.611 ± 1.964
1.305GlnPhe: 1.305 ± 1.336
1.305GlnGly: 1.305 ± 1.468
0.0GlnHis: 0.0 ± 0.0
1.305GlnIle: 1.305 ± 1.103
3.916GlnLys: 3.916 ± 1.661
3.916GlnLeu: 3.916 ± 2.636
0.0GlnMet: 0.0 ± 0.88
2.611GlnAsn: 2.611 ± 1.474
1.305GlnPro: 1.305 ± 1.103
1.305GlnGln: 1.305 ± 0.982
1.305GlnArg: 1.305 ± 0.982
7.833GlnSer: 7.833 ± 4.082
1.305GlnThr: 1.305 ± 0.982
5.222GlnVal: 5.222 ± 1.608
1.305GlnTrp: 1.305 ± 0.982
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.305ArgAla: 1.305 ± 1.103
0.0ArgCys: 0.0 ± 0.0
2.611ArgAsp: 2.611 ± 1.467
2.611ArgGlu: 2.611 ± 0.927
5.222ArgPhe: 5.222 ± 1.364
5.222ArgGly: 5.222 ± 0.94
3.916ArgHis: 3.916 ± 0.895
1.305ArgIle: 1.305 ± 1.103
3.916ArgLys: 3.916 ± 0.895
2.611ArgLeu: 2.611 ± 1.467
3.916ArgMet: 3.916 ± 1.299
1.305ArgAsn: 1.305 ± 0.982
1.305ArgPro: 1.305 ± 1.103
0.0ArgGln: 0.0 ± 0.0
2.611ArgArg: 2.611 ± 2.205
9.138ArgSer: 9.138 ± 3.475
5.222ArgThr: 5.222 ± 1.364
2.611ArgVal: 2.611 ± 2.104
1.305ArgTrp: 1.305 ± 1.103
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
10.444SerAla: 10.444 ± 2.744
0.0SerCys: 0.0 ± 0.0
5.222SerAsp: 5.222 ± 1.466
6.527SerGlu: 6.527 ± 3.703
3.916SerPhe: 3.916 ± 1.785
5.222SerGly: 5.222 ± 4.41
2.611SerHis: 2.611 ± 1.467
6.527SerIle: 6.527 ± 3.238
3.916SerLys: 3.916 ± 2.118
7.833SerLeu: 7.833 ± 3.857
2.611SerMet: 2.611 ± 0.927
2.611SerAsn: 2.611 ± 1.694
3.916SerPro: 3.916 ± 2.019
1.305SerGln: 1.305 ± 1.468
6.527SerArg: 6.527 ± 2.761
13.055SerSer: 13.055 ± 5.245
2.611SerThr: 2.611 ± 1.474
3.916SerVal: 3.916 ± 1.56
1.305SerTrp: 1.305 ± 0.982
6.527SerTyr: 6.527 ± 3.376
0.0SerXaa: 0.0 ± 0.0
Thr
1.305ThrAla: 1.305 ± 1.336
2.611ThrCys: 2.611 ± 0.927
6.527ThrAsp: 6.527 ± 2.314
5.222ThrGlu: 5.222 ± 0.94
2.611ThrPhe: 2.611 ± 1.964
5.222ThrGly: 5.222 ± 2.16
0.0ThrHis: 0.0 ± 0.0
2.611ThrIle: 2.611 ± 0.927
2.611ThrLys: 2.611 ± 0.927
3.916ThrLeu: 3.916 ± 2.452
1.305ThrMet: 1.305 ± 1.103
5.222ThrAsn: 5.222 ± 1.364
1.305ThrPro: 1.305 ± 1.336
1.305ThrGln: 1.305 ± 1.468
5.222ThrArg: 5.222 ± 2.026
3.916ThrSer: 3.916 ± 1.56
3.916ThrThr: 3.916 ± 1.785
2.611ThrVal: 2.611 ± 1.317
2.611ThrTrp: 2.611 ± 1.317
3.916ThrTyr: 3.916 ± 1.56
0.0ThrXaa: 0.0 ± 0.0
Val
3.916ValAla: 3.916 ± 1.661
2.611ValCys: 2.611 ± 2.205
1.305ValAsp: 1.305 ± 1.336
2.611ValGlu: 2.611 ± 1.964
0.0ValPhe: 0.0 ± 0.0
5.222ValGly: 5.222 ± 4.41
0.0ValHis: 0.0 ± 0.0
3.916ValIle: 3.916 ± 2.414
2.611ValLys: 2.611 ± 2.205
3.916ValLeu: 3.916 ± 2.972
1.305ValMet: 1.305 ± 0.982
3.916ValAsn: 3.916 ± 2.118
6.527ValPro: 6.527 ± 2.804
3.916ValGln: 3.916 ± 2.946
3.916ValArg: 3.916 ± 1.661
2.611ValSer: 2.611 ± 0.927
3.916ValThr: 3.916 ± 2.029
6.527ValVal: 6.527 ± 4.222
1.305ValTrp: 1.305 ± 1.103
1.305ValTyr: 1.305 ± 1.103
0.0ValXaa: 0.0 ± 0.0
Trp
3.916TrpAla: 3.916 ± 2.636
1.305TrpCys: 1.305 ± 1.103
1.305TrpAsp: 1.305 ± 0.982
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
3.916TrpLys: 3.916 ± 2.029
2.611TrpLeu: 2.611 ± 0.927
2.611TrpMet: 2.611 ± 1.474
1.305TrpAsn: 1.305 ± 0.982
1.305TrpPro: 1.305 ± 1.103
1.305TrpGln: 1.305 ± 1.336
0.0TrpArg: 0.0 ± 0.0
1.305TrpSer: 1.305 ± 1.468
0.0TrpThr: 0.0 ± 0.0
1.305TrpVal: 1.305 ± 1.468
0.0TrpTrp: 0.0 ± 0.0
1.305TrpTyr: 1.305 ± 1.468
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.305TyrAla: 1.305 ± 1.336
1.305TyrCys: 1.305 ± 0.982
3.916TyrAsp: 3.916 ± 0.895
0.0TyrGlu: 0.0 ± 0.0
6.527TyrPhe: 6.527 ± 2.314
1.305TyrGly: 1.305 ± 1.336
1.305TyrHis: 1.305 ± 1.103
5.222TyrIle: 5.222 ± 2.026
2.611TyrLys: 2.611 ± 1.317
2.611TyrLeu: 2.611 ± 1.467
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.0TyrPro: 0.0 ± 0.0
1.305TyrGln: 1.305 ± 1.468
0.0TyrArg: 0.0 ± 0.0
5.222TyrSer: 5.222 ± 1.855
3.916TyrThr: 3.916 ± 1.56
1.305TyrVal: 1.305 ± 1.336
1.305TyrTrp: 1.305 ± 1.336
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (767 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski