Amino acid dipepetide frequency for Crimson clover cryptic virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.638AlaAla: 5.638 ± 2.124
0.705AlaCys: 0.705 ± 0.506
2.114AlaAsp: 2.114 ± 0.555
2.819AlaGlu: 2.819 ± 0.098
0.705AlaPhe: 0.705 ± 0.506
2.114AlaGly: 2.114 ± 0.555
3.524AlaHis: 3.524 ± 0.604
4.228AlaIle: 4.228 ± 2.075
2.819AlaLys: 2.819 ± 0.866
2.819AlaLeu: 2.819 ± 1.062
1.409AlaMet: 1.409 ± 0.049
4.933AlaAsn: 4.933 ± 1.617
6.342AlaPro: 6.342 ± 1.226
2.819AlaGln: 2.819 ± 1.062
4.933AlaArg: 4.933 ± 1.275
4.228AlaSer: 4.228 ± 2.075
7.047AlaThr: 7.047 ± 2.173
4.933AlaVal: 4.933 ± 1.617
0.0AlaTrp: 0.0 ± 0.0
6.342AlaTyr: 6.342 ± 0.262
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.705CysCys: 0.705 ± 0.458
0.0CysAsp: 0.0 ± 0.0
0.705CysGlu: 0.705 ± 0.506
0.705CysPhe: 0.705 ± 0.506
0.705CysGly: 0.705 ± 0.458
0.0CysHis: 0.0 ± 0.0
1.409CysIle: 1.409 ± 0.049
1.409CysLys: 1.409 ± 0.049
0.705CysLeu: 0.705 ± 0.506
0.0CysMet: 0.0 ± 0.0
0.705CysAsn: 0.705 ± 0.458
0.0CysPro: 0.0 ± 0.0
0.705CysGln: 0.705 ± 0.458
1.409CysArg: 1.409 ± 0.915
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
2.114CysTyr: 2.114 ± 0.409
0.0CysXaa: 0.0 ± 0.0
Asp
4.933AspAla: 4.933 ± 0.311
0.0AspCys: 0.0 ± 0.0
5.638AspAsp: 5.638 ± 1.732
1.409AspGlu: 1.409 ± 0.049
3.524AspPhe: 3.524 ± 1.324
4.228AspGly: 4.228 ± 0.147
2.819AspHis: 2.819 ± 1.062
3.524AspIle: 3.524 ± 0.36
2.819AspLys: 2.819 ± 0.098
6.342AspLeu: 6.342 ± 2.63
0.705AspMet: 0.705 ± 0.458
4.228AspAsn: 4.228 ± 1.781
5.638AspPro: 5.638 ± 0.768
1.409AspGln: 1.409 ± 0.049
2.114AspArg: 2.114 ± 0.555
4.228AspSer: 4.228 ± 0.817
4.228AspThr: 4.228 ± 0.817
2.819AspVal: 2.819 ± 0.866
0.705AspTrp: 0.705 ± 0.458
3.524AspTyr: 3.524 ± 2.288
0.0AspXaa: 0.0 ± 0.0
Glu
5.638GluAla: 5.638 ± 1.16
0.0GluCys: 0.0 ± 0.0
3.524GluAsp: 3.524 ± 0.604
0.705GluGlu: 0.705 ± 0.506
2.819GluPhe: 2.819 ± 1.062
0.0GluGly: 0.0 ± 0.0
1.409GluHis: 1.409 ± 0.049
2.114GluIle: 2.114 ± 0.409
0.705GluLys: 0.705 ± 0.458
2.819GluLeu: 2.819 ± 0.866
2.114GluMet: 2.114 ± 0.409
4.228GluAsn: 4.228 ± 0.817
0.705GluPro: 0.705 ± 0.506
1.409GluGln: 1.409 ± 0.915
1.409GluArg: 1.409 ± 0.915
2.819GluSer: 2.819 ± 1.062
3.524GluThr: 3.524 ± 0.36
2.114GluVal: 2.114 ± 0.555
0.705GluTrp: 0.705 ± 0.458
3.524GluTyr: 3.524 ± 1.324
0.0GluXaa: 0.0 ± 0.0
Phe
2.819PheAla: 2.819 ± 1.062
2.114PheCys: 2.114 ± 0.409
1.409PheAsp: 1.409 ± 1.013
2.819PheGlu: 2.819 ± 0.866
2.114PhePhe: 2.114 ± 0.409
3.524PheGly: 3.524 ± 0.36
1.409PheHis: 1.409 ± 0.915
4.228PheIle: 4.228 ± 0.817
2.819PheLys: 2.819 ± 0.098
7.752PheLeu: 7.752 ± 0.213
0.705PheMet: 0.705 ± 0.458
5.638PheAsn: 5.638 ± 1.732
4.933PhePro: 4.933 ± 1.617
0.0PheGln: 0.0 ± 0.0
2.819PheArg: 2.819 ± 0.098
4.228PheSer: 4.228 ± 2.075
3.524PheThr: 3.524 ± 0.604
2.114PheVal: 2.114 ± 0.555
0.0PheTrp: 0.0 ± 0.0
1.409PheTyr: 1.409 ± 0.049
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
1.409GlyAsp: 1.409 ± 0.049
0.705GlyGlu: 0.705 ± 0.506
2.819GlyPhe: 2.819 ± 1.062
0.0GlyGly: 0.0 ± 0.0
0.705GlyHis: 0.705 ± 0.458
2.819GlyIle: 2.819 ± 0.098
0.705GlyLys: 0.705 ± 0.506
4.228GlyLeu: 4.228 ± 0.817
2.819GlyMet: 2.819 ± 0.098
0.705GlyAsn: 0.705 ± 0.458
1.409GlyPro: 1.409 ± 0.915
0.705GlyGln: 0.705 ± 0.458
1.409GlyArg: 1.409 ± 1.013
3.524GlySer: 3.524 ± 0.604
2.114GlyThr: 2.114 ± 0.409
1.409GlyVal: 1.409 ± 0.049
0.0GlyTrp: 0.0 ± 0.0
5.638GlyTyr: 5.638 ± 1.732
0.0GlyXaa: 0.0 ± 0.0
His
2.114HisAla: 2.114 ± 0.555
0.0HisCys: 0.0 ± 0.0
4.228HisAsp: 4.228 ± 1.111
0.0HisGlu: 0.0 ± 0.0
4.933HisPhe: 4.933 ± 1.275
1.409HisGly: 1.409 ± 0.049
0.705HisHis: 0.705 ± 0.506
2.114HisIle: 2.114 ± 0.409
1.409HisLys: 1.409 ± 0.915
1.409HisLeu: 1.409 ± 0.915
0.705HisMet: 0.705 ± 0.506
1.409HisAsn: 1.409 ± 0.915
1.409HisPro: 1.409 ± 0.049
2.114HisGln: 2.114 ± 0.409
0.705HisArg: 0.705 ± 0.458
2.114HisSer: 2.114 ± 0.555
3.524HisThr: 3.524 ± 1.568
3.524HisVal: 3.524 ± 1.568
0.0HisTrp: 0.0 ± 0.0
1.409HisTyr: 1.409 ± 0.049
0.0HisXaa: 0.0 ± 0.0
Ile
2.114IleAla: 2.114 ± 0.409
2.114IleCys: 2.114 ± 0.409
3.524IleAsp: 3.524 ± 1.324
2.819IleGlu: 2.819 ± 0.098
3.524IlePhe: 3.524 ± 0.36
2.114IleGly: 2.114 ± 0.409
2.114IleHis: 2.114 ± 0.409
3.524IleIle: 3.524 ± 0.36
3.524IleLys: 3.524 ± 0.36
4.228IleLeu: 4.228 ± 1.111
1.409IleMet: 1.409 ± 0.915
6.342IleAsn: 6.342 ± 0.702
3.524IlePro: 3.524 ± 0.36
2.819IleGln: 2.819 ± 1.83
5.638IleArg: 5.638 ± 1.16
2.819IleSer: 2.819 ± 0.866
3.524IleThr: 3.524 ± 0.604
1.409IleVal: 1.409 ± 0.049
0.0IleTrp: 0.0 ± 0.0
2.114IleTyr: 2.114 ± 0.409
0.0IleXaa: 0.0 ± 0.0
Lys
2.114LysAla: 2.114 ± 0.555
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
3.524LysGlu: 3.524 ± 1.324
2.114LysPhe: 2.114 ± 0.409
2.114LysGly: 2.114 ± 1.373
2.819LysHis: 2.819 ± 0.098
2.819LysIle: 2.819 ± 0.098
0.705LysLys: 0.705 ± 0.458
4.228LysLeu: 4.228 ± 0.147
0.0LysMet: 0.0 ± 0.0
0.705LysAsn: 0.705 ± 0.506
2.819LysPro: 2.819 ± 1.83
1.409LysGln: 1.409 ± 0.915
2.819LysArg: 2.819 ± 1.83
3.524LysSer: 3.524 ± 0.604
4.228LysThr: 4.228 ± 0.147
1.409LysVal: 1.409 ± 0.049
0.705LysTrp: 0.705 ± 0.458
3.524LysTyr: 3.524 ± 1.324
0.0LysXaa: 0.0 ± 0.0
Leu
2.114LeuAla: 2.114 ± 0.555
0.705LeuCys: 0.705 ± 0.458
7.047LeuAsp: 7.047 ± 1.684
4.228LeuGlu: 4.228 ± 2.745
5.638LeuPhe: 5.638 ± 2.124
2.819LeuGly: 2.819 ± 0.098
4.933LeuHis: 4.933 ± 1.275
4.228LeuIle: 4.228 ± 1.111
2.819LeuLys: 2.819 ± 0.866
6.342LeuLeu: 6.342 ± 0.262
2.114LeuMet: 2.114 ± 1.373
8.457LeuAsn: 8.457 ± 4.15
11.276LeuPro: 11.276 ± 2.319
2.114LeuGln: 2.114 ± 1.519
2.819LeuArg: 2.819 ± 1.062
3.524LeuSer: 3.524 ± 0.604
7.047LeuThr: 7.047 ± 0.245
5.638LeuVal: 5.638 ± 1.732
1.409LeuTrp: 1.409 ± 0.049
4.228LeuTyr: 4.228 ± 0.147
0.0LeuXaa: 0.0 ± 0.0
Met
1.409MetAla: 1.409 ± 0.049
0.0MetCys: 0.0 ± 0.0
0.705MetAsp: 0.705 ± 0.458
0.705MetGlu: 0.705 ± 0.458
2.114MetPhe: 2.114 ± 0.409
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.705MetIle: 0.705 ± 0.506
1.409MetLys: 1.409 ± 0.049
3.524MetLeu: 3.524 ± 0.36
0.0MetMet: 0.0 ± 0.0
0.705MetAsn: 0.705 ± 0.458
2.819MetPro: 2.819 ± 0.098
0.705MetGln: 0.705 ± 0.506
0.705MetArg: 0.705 ± 0.458
1.409MetSer: 1.409 ± 0.049
2.819MetThr: 2.819 ± 0.866
0.705MetVal: 0.705 ± 0.458
0.0MetTrp: 0.0 ± 0.0
2.819MetTyr: 2.819 ± 0.866
0.0MetXaa: 0.0 ± 0.0
Asn
8.457AsnAla: 8.457 ± 0.671
1.409AsnCys: 1.409 ± 1.013
3.524AsnAsp: 3.524 ± 0.604
3.524AsnGlu: 3.524 ± 0.36
1.409AsnPhe: 1.409 ± 0.049
2.114AsnGly: 2.114 ± 0.409
2.114AsnHis: 2.114 ± 0.409
2.819AsnIle: 2.819 ± 0.098
2.114AsnLys: 2.114 ± 0.409
7.047AsnLeu: 7.047 ± 0.719
2.819AsnMet: 2.819 ± 0.098
4.228AsnAsn: 4.228 ± 0.147
2.114AsnPro: 2.114 ± 1.519
0.705AsnGln: 0.705 ± 0.506
2.819AsnArg: 2.819 ± 0.866
4.228AsnSer: 4.228 ± 1.111
3.524AsnThr: 3.524 ± 0.604
3.524AsnVal: 3.524 ± 0.604
0.0AsnTrp: 0.0 ± 0.0
2.819AsnTyr: 2.819 ± 0.098
0.0AsnXaa: 0.0 ± 0.0
Pro
4.933ProAla: 4.933 ± 1.617
0.0ProCys: 0.0 ± 0.0
7.047ProAsp: 7.047 ± 1.684
2.819ProGlu: 2.819 ± 1.062
3.524ProPhe: 3.524 ± 0.36
2.114ProGly: 2.114 ± 1.519
1.409ProHis: 1.409 ± 0.049
6.342ProIle: 6.342 ± 3.154
2.114ProLys: 2.114 ± 1.373
9.161ProLeu: 9.161 ± 0.8
0.0ProMet: 0.0 ± 0.343
4.933ProAsn: 4.933 ± 2.581
3.524ProPro: 3.524 ± 0.36
0.705ProGln: 0.705 ± 0.506
3.524ProArg: 3.524 ± 1.568
6.342ProSer: 6.342 ± 0.262
4.933ProThr: 4.933 ± 1.275
5.638ProVal: 5.638 ± 1.16
0.0ProTrp: 0.0 ± 0.0
2.819ProTyr: 2.819 ± 0.098
0.0ProXaa: 0.0 ± 0.0
Gln
0.705GlnAla: 0.705 ± 0.458
0.705GlnCys: 0.705 ± 0.458
3.524GlnAsp: 3.524 ± 0.36
1.409GlnGlu: 1.409 ± 0.049
2.114GlnPhe: 2.114 ± 0.555
0.705GlnGly: 0.705 ± 0.506
0.705GlnHis: 0.705 ± 0.506
2.114GlnIle: 2.114 ± 1.373
2.114GlnLys: 2.114 ± 1.373
1.409GlnLeu: 1.409 ± 0.049
0.0GlnMet: 0.0 ± 0.0
0.705GlnAsn: 0.705 ± 0.506
1.409GlnPro: 1.409 ± 0.915
0.0GlnGln: 0.0 ± 0.0
2.114GlnArg: 2.114 ± 0.555
2.819GlnSer: 2.819 ± 0.098
0.0GlnThr: 0.0 ± 0.0
2.819GlnVal: 2.819 ± 0.098
0.705GlnTrp: 0.705 ± 0.506
0.705GlnTyr: 0.705 ± 0.458
0.0GlnXaa: 0.0 ± 0.0
Arg
2.819ArgAla: 2.819 ± 0.098
0.0ArgCys: 0.0 ± 0.0
3.524ArgAsp: 3.524 ± 1.324
2.114ArgGlu: 2.114 ± 0.555
2.819ArgPhe: 2.819 ± 0.098
0.705ArgGly: 0.705 ± 0.458
1.409ArgHis: 1.409 ± 1.013
1.409ArgIle: 1.409 ± 0.049
1.409ArgLys: 1.409 ± 0.915
4.933ArgLeu: 4.933 ± 0.653
2.819ArgMet: 2.819 ± 1.83
2.114ArgAsn: 2.114 ± 0.409
5.638ArgPro: 5.638 ± 1.16
1.409ArgGln: 1.409 ± 0.049
2.819ArgArg: 2.819 ± 0.098
4.228ArgSer: 4.228 ± 0.817
4.933ArgThr: 4.933 ± 0.653
3.524ArgVal: 3.524 ± 0.604
0.0ArgTrp: 0.0 ± 0.0
4.228ArgTyr: 4.228 ± 1.781
0.0ArgXaa: 0.0 ± 0.0
Ser
7.752SerAla: 7.752 ± 3.643
1.409SerCys: 1.409 ± 0.915
5.638SerAsp: 5.638 ± 1.732
3.524SerGlu: 3.524 ± 0.604
5.638SerPhe: 5.638 ± 0.196
2.114SerGly: 2.114 ± 0.555
2.819SerHis: 2.819 ± 0.098
1.409SerIle: 1.409 ± 1.013
4.933SerLys: 4.933 ± 1.275
4.933SerLeu: 4.933 ± 1.275
2.114SerMet: 2.114 ± 1.292
2.114SerAsn: 2.114 ± 0.555
2.819SerPro: 2.819 ± 1.062
0.705SerGln: 0.705 ± 0.506
3.524SerArg: 3.524 ± 0.604
4.933SerSer: 4.933 ± 1.617
7.047SerThr: 7.047 ± 0.245
2.114SerVal: 2.114 ± 0.555
1.409SerTrp: 1.409 ± 1.013
0.705SerTyr: 0.705 ± 0.458
0.0SerXaa: 0.0 ± 0.0
Thr
5.638ThrAla: 5.638 ± 4.052
0.705ThrCys: 0.705 ± 0.506
7.752ThrAsp: 7.752 ± 1.177
2.114ThrGlu: 2.114 ± 1.519
5.638ThrPhe: 5.638 ± 2.697
2.819ThrGly: 2.819 ± 0.866
0.705ThrHis: 0.705 ± 0.458
7.752ThrIle: 7.752 ± 0.213
4.228ThrLys: 4.228 ± 0.147
4.933ThrLeu: 4.933 ± 1.617
2.114ThrMet: 2.114 ± 0.409
2.114ThrAsn: 2.114 ± 1.519
2.819ThrPro: 2.819 ± 0.098
2.819ThrGln: 2.819 ± 0.866
3.524ThrArg: 3.524 ± 0.36
3.524ThrSer: 3.524 ± 1.568
7.752ThrThr: 7.752 ± 1.715
3.524ThrVal: 3.524 ± 0.604
0.705ThrTrp: 0.705 ± 0.506
5.638ThrTyr: 5.638 ± 0.196
0.0ThrXaa: 0.0 ± 0.0
Val
3.524ValAla: 3.524 ± 0.604
0.0ValCys: 0.0 ± 0.0
2.819ValAsp: 2.819 ± 0.098
1.409ValGlu: 1.409 ± 0.049
2.819ValPhe: 2.819 ± 2.026
0.0ValGly: 0.0 ± 0.0
2.819ValHis: 2.819 ± 2.026
3.524ValIle: 3.524 ± 2.288
0.0ValLys: 0.0 ± 0.0
7.752ValLeu: 7.752 ± 1.715
0.705ValMet: 0.705 ± 0.506
2.114ValAsn: 2.114 ± 0.555
7.752ValPro: 7.752 ± 0.751
0.705ValGln: 0.705 ± 0.458
3.524ValArg: 3.524 ± 0.36
2.114ValSer: 2.114 ± 0.555
3.524ValThr: 3.524 ± 0.604
2.114ValVal: 2.114 ± 0.409
0.0ValTrp: 0.0 ± 0.0
2.819ValTyr: 2.819 ± 0.866
0.0ValXaa: 0.0 ± 0.0
Trp
0.705TrpAla: 0.705 ± 0.506
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.409TrpLys: 1.409 ± 0.049
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.705TrpAsn: 0.705 ± 0.458
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.114TrpSer: 2.114 ± 0.555
0.705TrpThr: 0.705 ± 0.506
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.705TrpTyr: 0.705 ± 0.458
0.0TrpXaa: 0.0 ± 0.0
Tyr
7.047TyrAla: 7.047 ± 1.684
0.705TyrCys: 0.705 ± 0.458
1.409TyrAsp: 1.409 ± 0.049
4.933TyrGlu: 4.933 ± 1.275
1.409TyrPhe: 1.409 ± 0.049
3.524TyrGly: 3.524 ± 0.36
2.819TyrHis: 2.819 ± 0.866
2.114TyrIle: 2.114 ± 0.409
2.114TyrLys: 2.114 ± 0.555
4.933TyrLeu: 4.933 ± 1.275
0.0TyrMet: 0.0 ± 0.0
4.228TyrAsn: 4.228 ± 2.745
5.638TyrPro: 5.638 ± 0.768
3.524TyrGln: 3.524 ± 0.36
4.228TyrArg: 4.228 ± 1.781
4.933TyrSer: 4.933 ± 2.239
2.819TyrThr: 2.819 ± 1.062
0.705TyrVal: 0.705 ± 0.506
0.0TyrTrp: 0.0 ± 0.0
2.114TyrTyr: 2.114 ± 0.409
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1420 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski