Amino acid dipepetide frequency for Sediminibacterium goheungense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.134AlaAla: 7.134 ± 0.1	0.699AlaCys: 0.699 ± 0.026	4.403AlaAsp: 4.403 ± 0.076	4.212AlaGlu: 4.212 ± 0.061	3.552AlaPhe: 3.552 ± 0.055	5.949AlaGly: 5.949 ± 0.077	1.268AlaHis: 1.268 ± 0.035	5.592AlaIle: 5.592 ± 0.073	4.472AlaLys: 4.472 ± 0.072	6.825AlaLeu: 6.825 ± 0.088	1.88AlaMet: 1.88 ± 0.048	3.66AlaAsn: 3.66 ± 0.082	2.5AlaPro: 2.5 ± 0.062	2.747AlaGln: 2.747 ± 0.057	2.728AlaArg: 2.728 ± 0.053	4.679AlaSer: 4.679 ± 0.074	4.511AlaThr: 4.511 ± 0.099	5.161AlaVal: 5.161 ± 0.076	0.817AlaTrp: 0.817 ± 0.025	2.837AlaTyr: 2.837 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.541CysAla: 0.541 ± 0.023	0.137CysCys: 0.137 ± 0.012	0.402CysAsp: 0.402 ± 0.022	0.435CysGlu: 0.435 ± 0.02	0.501CysPhe: 0.501 ± 0.02	0.722CysGly: 0.722 ± 0.028	0.199CysHis: 0.199 ± 0.013	0.716CysIle: 0.716 ± 0.027	0.571CysLys: 0.571 ± 0.025	0.773CysLeu: 0.773 ± 0.029	0.244CysMet: 0.244 ± 0.015	0.465CysAsn: 0.465 ± 0.022	0.352CysPro: 0.352 ± 0.019	0.244CysGln: 0.244 ± 0.016	0.314CysArg: 0.314 ± 0.016	0.602CysSer: 0.602 ± 0.034	0.55CysThr: 0.55 ± 0.026	0.538CysVal: 0.538 ± 0.026	0.127CysTrp: 0.127 ± 0.01	0.343CysTyr: 0.343 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	4.028AspAla: 4.028 ± 0.068	0.44AspCys: 0.44 ± 0.021	2.349AspAsp: 2.349 ± 0.055	3.137AspGlu: 3.137 ± 0.059	2.745AspPhe: 2.745 ± 0.051	3.553AspGly: 3.553 ± 0.07	1.034AspHis: 1.034 ± 0.026	4.104AspIle: 4.104 ± 0.071	3.569AspLys: 3.569 ± 0.066	4.433AspLeu: 4.433 ± 0.076	1.269AspMet: 1.269 ± 0.033	2.341AspAsn: 2.341 ± 0.046	1.973AspPro: 1.973 ± 0.047	1.759AspGln: 1.759 ± 0.041	2.013AspArg: 2.013 ± 0.045	2.943AspSer: 2.943 ± 0.069	2.884AspThr: 2.884 ± 0.063	2.964AspVal: 2.964 ± 0.049	0.683AspTrp: 0.683 ± 0.028	2.239AspTyr: 2.239 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	4.381GluAla: 4.381 ± 0.076	0.371GluCys: 0.371 ± 0.018	2.422GluAsp: 2.422 ± 0.056	3.896GluGlu: 3.896 ± 0.079	2.101GluPhe: 2.101 ± 0.044	3.353GluGly: 3.353 ± 0.061	1.056GluHis: 1.056 ± 0.031	4.096GluIle: 4.096 ± 0.072	5.261GluLys: 5.261 ± 0.081	5.477GluLeu: 5.477 ± 0.088	1.697GluMet: 1.697 ± 0.044	3.028GluAsn: 3.028 ± 0.058	1.709GluPro: 1.709 ± 0.046	2.789GluGln: 2.789 ± 0.049	2.508GluArg: 2.508 ± 0.053	2.693GluSer: 2.693 ± 0.047	3.003GluThr: 3.003 ± 0.048	3.539GluVal: 3.539 ± 0.072	0.792GluTrp: 0.792 ± 0.027	2.0GluTyr: 2.0 ± 0.046	0.0GluXaa: 0.0 ± 0.0
Phe	3.401PheAla: 3.401 ± 0.059	0.492PheCys: 0.492 ± 0.023	2.656PheAsp: 2.656 ± 0.055	2.64PheGlu: 2.64 ± 0.049	2.746PhePhe: 2.746 ± 0.062	3.364PheGly: 3.364 ± 0.065	0.929PheHis: 0.929 ± 0.029	3.528PheIle: 3.528 ± 0.061	2.692PheLys: 2.692 ± 0.051	4.387PheLeu: 4.387 ± 0.068	1.177PheMet: 1.177 ± 0.034	2.709PheAsn: 2.709 ± 0.057	1.746PhePro: 1.746 ± 0.042	1.568PheGln: 1.568 ± 0.039	2.101PheArg: 2.101 ± 0.046	3.842PheSer: 3.842 ± 0.071	3.372PheThr: 3.372 ± 0.065	2.851PheVal: 2.851 ± 0.052	0.622PheTrp: 0.622 ± 0.027	1.989PheTyr: 1.989 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	4.806GlyAla: 4.806 ± 0.094	0.75GlyCys: 0.75 ± 0.034	3.19GlyAsp: 3.19 ± 0.056	3.328GlyGlu: 3.328 ± 0.07	3.696GlyPhe: 3.696 ± 0.065	5.161GlyGly: 5.161 ± 0.123	1.191GlyHis: 1.191 ± 0.033	5.618GlyIle: 5.618 ± 0.075	5.418GlyLys: 5.418 ± 0.075	6.036GlyLeu: 6.036 ± 0.084	1.916GlyMet: 1.916 ± 0.044	3.864GlyAsn: 3.864 ± 0.08	1.62GlyPro: 1.62 ± 0.043	2.166GlyGln: 2.166 ± 0.047	2.616GlyArg: 2.616 ± 0.054	4.51GlySer: 4.51 ± 0.088	4.51GlyThr: 4.51 ± 0.116	4.231GlyVal: 4.231 ± 0.072	1.063GlyTrp: 1.063 ± 0.037	3.075GlyTyr: 3.075 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.31HisAla: 1.31 ± 0.04	0.226HisCys: 0.226 ± 0.013	0.855HisAsp: 0.855 ± 0.03	1.048HisGlu: 1.048 ± 0.029	1.239HisPhe: 1.239 ± 0.037	1.18HisGly: 1.18 ± 0.038	0.584HisHis: 0.584 ± 0.027	1.5HisIle: 1.5 ± 0.041	1.108HisLys: 1.108 ± 0.035	1.877HisLeu: 1.877 ± 0.045	0.399HisMet: 0.399 ± 0.019	0.876HisAsn: 0.876 ± 0.035	1.054HisPro: 1.054 ± 0.033	0.828HisGln: 0.828 ± 0.029	0.84HisArg: 0.84 ± 0.033	1.099HisSer: 1.099 ± 0.029	1.205HisThr: 1.205 ± 0.031	0.986HisVal: 0.986 ± 0.029	0.255HisTrp: 0.255 ± 0.016	0.933HisTyr: 0.933 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.812IleAla: 5.812 ± 0.074	0.853IleCys: 0.853 ± 0.029	4.09IleAsp: 4.09 ± 0.071	4.306IleGlu: 4.306 ± 0.072	3.092IlePhe: 3.092 ± 0.059	4.833IleGly: 4.833 ± 0.075	1.58IleHis: 1.58 ± 0.044	5.091IleIle: 5.091 ± 0.074	4.42IleLys: 4.42 ± 0.075	6.255IleLeu: 6.255 ± 0.097	1.439IleMet: 1.439 ± 0.039	3.881IleAsn: 3.881 ± 0.067	3.307IlePro: 3.307 ± 0.056	2.981IleGln: 2.981 ± 0.056	3.494IleArg: 3.494 ± 0.066	5.022IleSer: 5.022 ± 0.075	4.815IleThr: 4.815 ± 0.085	4.43IleVal: 4.43 ± 0.076	0.759IleTrp: 0.759 ± 0.026	2.423IleTyr: 2.423 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	5.264LysAla: 5.264 ± 0.088	0.313LysCys: 0.313 ± 0.017	3.778LysAsp: 3.778 ± 0.07	5.195LysGlu: 5.195 ± 0.082	2.164LysPhe: 2.164 ± 0.047	4.661LysGly: 4.661 ± 0.076	1.169LysHis: 1.169 ± 0.032	4.683LysIle: 4.683 ± 0.078	6.104LysLys: 6.104 ± 0.083	5.774LysLeu: 5.774 ± 0.074	2.024LysMet: 2.024 ± 0.044	3.808LysAsn: 3.808 ± 0.065	2.614LysPro: 2.614 ± 0.056	3.106LysGln: 3.106 ± 0.057	2.786LysArg: 2.786 ± 0.054	3.467LysSer: 3.467 ± 0.063	4.15LysThr: 4.15 ± 0.06	4.039LysVal: 4.039 ± 0.063	0.85LysTrp: 0.85 ± 0.028	2.554LysTyr: 2.554 ± 0.053	0.0LysXaa: 0.0 ± 0.0
Leu	6.458LeuAla: 6.458 ± 0.082	0.846LeuCys: 0.846 ± 0.031	4.258LeuAsp: 4.258 ± 0.07	4.707LeuGlu: 4.707 ± 0.075	4.959LeuPhe: 4.959 ± 0.075	5.661LeuGly: 5.661 ± 0.092	1.948LeuHis: 1.948 ± 0.051	6.379LeuIle: 6.379 ± 0.087	6.337LeuLys: 6.337 ± 0.079	10.087LeuLeu: 10.087 ± 0.151	2.275LeuMet: 2.275 ± 0.049	4.838LeuAsn: 4.838 ± 0.073	4.203LeuPro: 4.203 ± 0.062	4.348LeuGln: 4.348 ± 0.079	3.841LeuArg: 3.841 ± 0.062	6.931LeuSer: 6.931 ± 0.102	5.313LeuThr: 5.313 ± 0.076	5.722LeuVal: 5.722 ± 0.076	0.954LeuTrp: 0.954 ± 0.034	3.352LeuTyr: 3.352 ± 0.066	0.0LeuXaa: 0.0 ± 0.0
Met	1.932MetAla: 1.932 ± 0.045	0.139MetCys: 0.139 ± 0.013	1.21MetAsp: 1.21 ± 0.033	1.477MetGlu: 1.477 ± 0.045	0.879MetPhe: 0.879 ± 0.03	1.739MetGly: 1.739 ± 0.044	0.522MetHis: 0.522 ± 0.023	1.756MetIle: 1.756 ± 0.042	2.152MetLys: 2.152 ± 0.045	2.325MetLeu: 2.325 ± 0.057	0.771MetMet: 0.771 ± 0.029	1.393MetAsn: 1.393 ± 0.04	1.12MetPro: 1.12 ± 0.032	1.185MetGln: 1.185 ± 0.038	1.163MetArg: 1.163 ± 0.036	1.542MetSer: 1.542 ± 0.039	1.151MetThr: 1.151 ± 0.03	1.63MetVal: 1.63 ± 0.041	0.205MetTrp: 0.205 ± 0.014	0.737MetTyr: 0.737 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.979AsnAla: 3.979 ± 0.093	0.487AsnCys: 0.487 ± 0.026	2.627AsnAsp: 2.627 ± 0.063	2.848AsnGlu: 2.848 ± 0.057	2.326AsnPhe: 2.326 ± 0.056	4.18AsnGly: 4.18 ± 0.097	1.015AsnHis: 1.015 ± 0.03	4.159AsnIle: 4.159 ± 0.082	3.415AsnLys: 3.415 ± 0.066	4.42AsnLeu: 4.42 ± 0.082	1.183AsnMet: 1.183 ± 0.032	3.134AsnAsn: 3.134 ± 0.075	2.686AsnPro: 2.686 ± 0.052	2.015AsnGln: 2.015 ± 0.045	2.474AsnArg: 2.474 ± 0.054	2.935AsnSer: 2.935 ± 0.064	3.486AsnThr: 3.486 ± 0.083	2.716AsnVal: 2.716 ± 0.061	0.808AsnTrp: 0.808 ± 0.03	2.223AsnTyr: 2.223 ± 0.052	0.0AsnXaa: 0.0 ± 0.0
Pro	3.432ProAla: 3.432 ± 0.064	0.231ProCys: 0.231 ± 0.014	2.521ProAsp: 2.521 ± 0.049	2.601ProGlu: 2.601 ± 0.048	2.015ProPhe: 2.015 ± 0.05	2.803ProGly: 2.803 ± 0.051	0.661ProHis: 0.661 ± 0.03	2.297ProIle: 2.297 ± 0.048	2.054ProLys: 2.054 ± 0.048	3.451ProLeu: 3.451 ± 0.052	0.821ProMet: 0.821 ± 0.026	1.911ProAsn: 1.911 ± 0.049	1.079ProPro: 1.079 ± 0.039	1.439ProGln: 1.439 ± 0.037	1.182ProArg: 1.182 ± 0.029	2.402ProSer: 2.402 ± 0.048	2.021ProThr: 2.021 ± 0.051	3.572ProVal: 3.572 ± 0.065	0.463ProTrp: 0.463 ± 0.023	1.543ProTyr: 1.543 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	2.659GlnAla: 2.659 ± 0.052	0.235GlnCys: 0.235 ± 0.016	1.535GlnAsp: 1.535 ± 0.038	2.108GlnGlu: 2.108 ± 0.039	1.92GlnPhe: 1.92 ± 0.039	2.002GlnGly: 2.002 ± 0.045	0.913GlnHis: 0.913 ± 0.033	2.508GlnIle: 2.508 ± 0.056	2.973GlnLys: 2.973 ± 0.057	4.836GlnLeu: 4.836 ± 0.075	1.055GlnMet: 1.055 ± 0.032	1.843GlnAsn: 1.843 ± 0.046	1.753GlnPro: 1.753 ± 0.043	2.777GlnGln: 2.777 ± 0.052	1.756GlnArg: 1.756 ± 0.041	2.264GlnSer: 2.264 ± 0.051	2.231GlnThr: 2.231 ± 0.047	2.576GlnVal: 2.576 ± 0.048	0.604GlnTrp: 0.604 ± 0.025	1.791GlnTyr: 1.791 ± 0.045	0.0GlnXaa: 0.0 ± 0.0
Arg	2.375ArgAla: 2.375 ± 0.051	0.261ArgCys: 0.261 ± 0.012	1.955ArgAsp: 1.955 ± 0.049	2.272ArgGlu: 2.272 ± 0.055	2.44ArgPhe: 2.44 ± 0.05	2.218ArgGly: 2.218 ± 0.047	0.71ArgHis: 0.71 ± 0.03	3.486ArgIle: 3.486 ± 0.056	3.335ArgLys: 3.335 ± 0.055	3.87ArgLeu: 3.87 ± 0.061	1.284ArgMet: 1.284 ± 0.04	2.587ArgAsn: 2.587 ± 0.052	1.422ArgPro: 1.422 ± 0.039	1.614ArgGln: 1.614 ± 0.039	1.7ArgArg: 1.7 ± 0.046	2.416ArgSer: 2.416 ± 0.048	2.187ArgThr: 2.187 ± 0.054	2.453ArgVal: 2.453 ± 0.046	0.629ArgTrp: 0.629 ± 0.024	1.906ArgTyr: 1.906 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	4.632SerAla: 4.632 ± 0.078	0.617SerCys: 0.617 ± 0.026	2.905SerAsp: 2.905 ± 0.051	2.758SerGlu: 2.758 ± 0.047	4.043SerPhe: 4.043 ± 0.062	4.915SerGly: 4.915 ± 0.091	1.064SerHis: 1.064 ± 0.033	4.91SerIle: 4.91 ± 0.077	3.569SerLys: 3.569 ± 0.058	6.129SerLeu: 6.129 ± 0.075	1.511SerMet: 1.511 ± 0.039	3.241SerAsn: 3.241 ± 0.091	2.204SerPro: 2.204 ± 0.046	2.009SerGln: 2.009 ± 0.049	2.41SerArg: 2.41 ± 0.045	4.2SerSer: 4.2 ± 0.09	3.546SerThr: 3.546 ± 0.072	4.367SerVal: 4.367 ± 0.077	0.857SerTrp: 0.857 ± 0.031	2.718SerTyr: 2.718 ± 0.061	0.0SerXaa: 0.0 ± 0.0
Thr	5.146ThrAla: 5.146 ± 0.102	0.49ThrCys: 0.49 ± 0.023	3.505ThrAsp: 3.505 ± 0.062	3.269ThrGlu: 3.269 ± 0.061	2.292ThrPhe: 2.292 ± 0.05	5.364ThrGly: 5.364 ± 0.099	1.16ThrHis: 1.16 ± 0.037	4.618ThrIle: 4.618 ± 0.076	3.206ThrLys: 3.206 ± 0.062	5.351ThrLeu: 5.351 ± 0.084	1.176ThrMet: 1.176 ± 0.035	3.013ThrAsn: 3.013 ± 0.083	2.573ThrPro: 2.573 ± 0.066	2.001ThrGln: 2.001 ± 0.044	2.191ThrArg: 2.191 ± 0.051	3.527ThrSer: 3.527 ± 0.082	3.862ThrThr: 3.862 ± 0.111	4.534ThrVal: 4.534 ± 0.125	0.667ThrTrp: 0.667 ± 0.025	2.29ThrTyr: 2.29 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	4.695ValAla: 4.695 ± 0.077	0.698ValCys: 0.698 ± 0.03	3.113ValAsp: 3.113 ± 0.059	3.286ValGlu: 3.286 ± 0.064	3.309ValPhe: 3.309 ± 0.057	3.638ValGly: 3.638 ± 0.066	1.177ValHis: 1.177 ± 0.032	4.49ValIle: 4.49 ± 0.067	4.354ValLys: 4.354 ± 0.069	6.098ValLeu: 6.098 ± 0.082	1.596ValMet: 1.596 ± 0.043	3.587ValAsn: 3.587 ± 0.066	2.584ValPro: 2.584 ± 0.053	2.375ValGln: 2.375 ± 0.045	2.421ValArg: 2.421 ± 0.046	4.386ValSer: 4.386 ± 0.077	4.165ValThr: 4.165 ± 0.123	4.34ValVal: 4.34 ± 0.072	0.76ValTrp: 0.76 ± 0.024	2.524ValTyr: 2.524 ± 0.054	0.0ValXaa: 0.0 ± 0.0
Trp	0.725TrpAla: 0.725 ± 0.028	0.121TrpCys: 0.121 ± 0.011	0.664TrpAsp: 0.664 ± 0.026	0.612TrpGlu: 0.612 ± 0.022	0.61TrpPhe: 0.61 ± 0.027	0.817TrpGly: 0.817 ± 0.032	0.275TrpHis: 0.275 ± 0.017	0.889TrpIle: 0.889 ± 0.029	0.949TrpLys: 0.949 ± 0.03	1.31TrpLeu: 1.31 ± 0.041	0.474TrpMet: 0.474 ± 0.021	0.76TrpAsn: 0.76 ± 0.027	0.33TrpPro: 0.33 ± 0.018	0.605TrpGln: 0.605 ± 0.023	0.584TrpArg: 0.584 ± 0.024	0.743TrpSer: 0.743 ± 0.03	0.64TrpThr: 0.64 ± 0.025	0.83TrpVal: 0.83 ± 0.03	0.255TrpTrp: 0.255 ± 0.017	0.533TrpTyr: 0.533 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.917TyrAla: 2.917 ± 0.056	0.373TyrCys: 0.373 ± 0.02	2.023TyrAsp: 2.023 ± 0.045	2.037TyrGlu: 2.037 ± 0.049	2.183TyrPhe: 2.183 ± 0.049	2.652TyrGly: 2.652 ± 0.048	0.947TyrHis: 0.947 ± 0.033	2.461TyrIle: 2.461 ± 0.047	2.544TyrLys: 2.544 ± 0.051	3.704TyrLeu: 3.704 ± 0.061	0.835TyrMet: 0.835 ± 0.032	2.179TyrAsn: 2.179 ± 0.049	1.671TyrPro: 1.671 ± 0.044	1.783TyrGln: 1.783 ± 0.039	1.997TyrArg: 1.997 ± 0.048	2.403TyrSer: 2.403 ± 0.044	2.633TyrThr: 2.633 ± 0.063	2.115TyrVal: 2.115 ± 0.042	0.555TyrTrp: 0.555 ± 0.024	1.904TyrTyr: 1.904 ± 0.051	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3224 proteins (1116394 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---