Amino acid dipepetide frequency for Apis mellifera associated microvirus 55

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.995AlaAla: 3.995 ± 1.02
1.142AlaCys: 1.142 ± 1.603
7.991AlaAsp: 7.991 ± 2.087
4.566AlaGlu: 4.566 ± 2.718
2.283AlaPhe: 2.283 ± 0.379
3.425AlaGly: 3.425 ± 2.201
1.712AlaHis: 1.712 ± 0.959
2.283AlaIle: 2.283 ± 0.767
3.995AlaLys: 3.995 ± 2.421
3.995AlaLeu: 3.995 ± 0.54
0.571AlaMet: 0.571 ± 0.615
3.425AlaAsn: 3.425 ± 0.517
2.283AlaPro: 2.283 ± 0.887
2.283AlaGln: 2.283 ± 1.694
2.283AlaArg: 2.283 ± 1.118
7.991AlaSer: 7.991 ± 2.305
1.712AlaThr: 1.712 ± 1.101
2.854AlaVal: 2.854 ± 0.901
0.571AlaTrp: 0.571 ± 0.414
3.425AlaTyr: 3.425 ± 1.321
0.0AlaXaa: 0.0 ± 0.0
Cys
1.712CysAla: 1.712 ± 1.119
0.0CysCys: 0.0 ± 0.0
0.571CysAsp: 0.571 ± 0.414
0.0CysGlu: 0.0 ± 0.0
1.712CysPhe: 1.712 ± 1.324
0.571CysGly: 0.571 ± 0.441
0.0CysHis: 0.0 ± 0.0
1.712CysIle: 1.712 ± 1.324
0.0CysLys: 0.0 ± 0.0
1.712CysLeu: 1.712 ± 0.714
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.571CysPro: 0.571 ± 0.801
1.142CysGln: 1.142 ± 0.772
0.571CysArg: 0.571 ± 0.715
1.142CysSer: 1.142 ± 0.772
0.571CysThr: 0.571 ± 0.715
2.854CysVal: 2.854 ± 0.901
0.571CysTrp: 0.571 ± 0.441
1.712CysTyr: 1.712 ± 0.714
0.0CysXaa: 0.0 ± 0.0
Asp
4.566AspAla: 4.566 ± 1.454
1.142AspCys: 1.142 ± 0.611
2.283AspAsp: 2.283 ± 0.764
6.849AspGlu: 6.849 ± 1.748
5.137AspPhe: 5.137 ± 0.983
1.142AspGly: 1.142 ± 0.827
3.425AspHis: 3.425 ± 1.146
3.425AspIle: 3.425 ± 1.836
4.566AspLys: 4.566 ± 1.142
5.708AspLeu: 5.708 ± 1.53
1.712AspMet: 1.712 ± 0.904
1.712AspAsn: 1.712 ± 0.663
4.566AspPro: 4.566 ± 2.146
0.0AspGln: 0.0 ± 0.0
4.566AspArg: 4.566 ± 1.528
3.995AspSer: 3.995 ± 1.42
3.425AspThr: 3.425 ± 1.045
4.566AspVal: 4.566 ± 0.835
1.142AspTrp: 1.142 ± 0.882
2.283AspTyr: 2.283 ± 0.379
0.0AspXaa: 0.0 ± 0.0
Glu
3.995GluAla: 3.995 ± 0.822
0.0GluCys: 0.0 ± 0.0
2.283GluAsp: 2.283 ± 0.711
1.142GluGlu: 1.142 ± 0.882
2.854GluPhe: 2.854 ± 0.736
2.283GluGly: 2.283 ± 0.502
1.712GluHis: 1.712 ± 1.324
4.566GluIle: 4.566 ± 2.116
1.142GluLys: 1.142 ± 0.382
6.849GluLeu: 6.849 ± 1.639
0.571GluMet: 0.571 ± 0.615
1.712GluAsn: 1.712 ± 0.904
0.571GluPro: 0.571 ± 0.715
0.571GluGln: 0.571 ± 0.615
2.283GluArg: 2.283 ± 1.238
6.849GluSer: 6.849 ± 1.484
1.712GluThr: 1.712 ± 1.324
2.283GluVal: 2.283 ± 1.223
0.0GluTrp: 0.0 ± 0.0
3.425GluTyr: 3.425 ± 1.429
0.0GluXaa: 0.0 ± 0.0
Phe
2.854PheAla: 2.854 ± 1.198
0.571PheCys: 0.571 ± 0.441
6.279PheAsp: 6.279 ± 2.725
0.571PheGlu: 0.571 ± 0.414
2.283PhePhe: 2.283 ± 0.764
4.566PheGly: 4.566 ± 1.285
2.854PheHis: 2.854 ± 1.057
2.854PheIle: 2.854 ± 1.472
1.712PheLys: 1.712 ± 0.663
1.142PheLeu: 1.142 ± 0.382
0.0PheMet: 0.0 ± 0.0
5.137PheAsn: 5.137 ± 0.983
2.283PhePro: 2.283 ± 0.764
1.712PheGln: 1.712 ± 0.714
1.712PheArg: 1.712 ± 0.698
3.425PheSer: 3.425 ± 1.429
2.283PheThr: 2.283 ± 0.379
5.137PheVal: 5.137 ± 1.514
0.0PheTrp: 0.0 ± 0.0
1.712PheTyr: 1.712 ± 0.767
0.0PheXaa: 0.0 ± 0.0
Gly
2.854GlyAla: 2.854 ± 0.736
0.571GlyCys: 0.571 ± 0.441
3.425GlyAsp: 3.425 ± 0.517
0.571GlyGlu: 0.571 ± 0.441
6.279GlyPhe: 6.279 ± 2.192
1.712GlyGly: 1.712 ± 0.296
1.142GlyHis: 1.142 ± 0.382
6.279GlyIle: 6.279 ± 2.431
5.137GlyLys: 5.137 ± 0.79
4.566GlyLeu: 4.566 ± 3.083
0.0GlyMet: 0.0 ± 0.0
2.854GlyAsn: 2.854 ± 1.198
1.142GlyPro: 1.142 ± 0.882
2.854GlyGln: 2.854 ± 1.634
2.854GlyArg: 2.854 ± 1.0
3.995GlySer: 3.995 ± 3.554
2.283GlyThr: 2.283 ± 1.098
3.995GlyVal: 3.995 ± 0.999
1.142GlyTrp: 1.142 ± 0.382
3.425GlyTyr: 3.425 ± 1.429
0.0GlyXaa: 0.0 ± 0.0
His
2.854HisAla: 2.854 ± 0.924
1.142HisCys: 1.142 ± 1.138
1.712HisAsp: 1.712 ± 1.057
0.571HisGlu: 0.571 ± 0.414
1.712HisPhe: 1.712 ± 0.663
3.425HisGly: 3.425 ± 1.326
0.0HisHis: 0.0 ± 0.0
1.712HisIle: 1.712 ± 0.714
1.142HisLys: 1.142 ± 0.611
2.283HisLeu: 2.283 ± 1.238
0.571HisMet: 0.571 ± 0.414
0.571HisAsn: 0.571 ± 0.441
1.142HisPro: 1.142 ± 0.867
0.571HisGln: 0.571 ± 0.414
1.142HisArg: 1.142 ± 0.882
1.712HisSer: 1.712 ± 1.057
0.571HisThr: 0.571 ± 0.441
1.712HisVal: 1.712 ± 0.714
0.0HisTrp: 0.0 ± 0.0
1.142HisTyr: 1.142 ± 0.772
0.0HisXaa: 0.0 ± 0.0
Ile
1.142IleAla: 1.142 ± 0.611
0.0IleCys: 0.0 ± 0.0
6.279IleAsp: 6.279 ± 1.876
5.708IleGlu: 5.708 ± 1.382
2.854IlePhe: 2.854 ± 2.068
2.854IleGly: 2.854 ± 1.472
1.142IleHis: 1.142 ± 1.011
2.854IleIle: 2.854 ± 0.803
2.854IleLys: 2.854 ± 1.604
3.995IleLeu: 3.995 ± 0.627
1.712IleMet: 1.712 ± 0.886
4.566IleAsn: 4.566 ± 0.691
6.279IlePro: 6.279 ± 1.512
2.854IleGln: 2.854 ± 1.057
2.283IleArg: 2.283 ± 1.238
6.849IleSer: 6.849 ± 1.284
2.283IleThr: 2.283 ± 0.502
3.995IleVal: 3.995 ± 0.888
0.0IleTrp: 0.0 ± 0.0
0.571IleTyr: 0.571 ± 0.441
0.0IleXaa: 0.0 ± 0.0
Lys
3.425LysAla: 3.425 ± 0.65
0.571LysCys: 0.571 ± 0.441
3.995LysAsp: 3.995 ± 0.54
4.566LysGlu: 4.566 ± 2.475
2.283LysPhe: 2.283 ± 1.654
2.854LysGly: 2.854 ± 0.298
1.712LysHis: 1.712 ± 0.714
3.995LysIle: 3.995 ± 1.471
1.142LysLys: 1.142 ± 0.882
3.995LysLeu: 3.995 ± 2.031
4.566LysMet: 4.566 ± 1.794
3.425LysAsn: 3.425 ± 1.045
1.712LysPro: 1.712 ± 1.324
2.854LysGln: 2.854 ± 1.447
2.283LysArg: 2.283 ± 0.856
5.708LysSer: 5.708 ± 2.098
1.712LysThr: 1.712 ± 0.296
5.137LysVal: 5.137 ± 1.875
1.142LysTrp: 1.142 ± 0.382
5.137LysTyr: 5.137 ± 2.63
0.0LysXaa: 0.0 ± 0.0
Leu
6.849LeuAla: 6.849 ± 4.572
1.142LeuCys: 1.142 ± 0.382
6.279LeuAsp: 6.279 ± 1.644
4.566LeuGlu: 4.566 ± 1.645
3.995LeuPhe: 3.995 ± 0.697
4.566LeuGly: 4.566 ± 0.759
4.566LeuHis: 4.566 ± 1.136
2.283LeuIle: 2.283 ± 1.238
5.708LeuLys: 5.708 ± 1.097
9.132LeuLeu: 9.132 ± 2.371
1.712LeuMet: 1.712 ± 1.416
7.42LeuAsn: 7.42 ± 2.656
3.995LeuPro: 3.995 ± 1.382
5.137LeuGln: 5.137 ± 0.79
6.279LeuArg: 6.279 ± 1.675
7.42LeuSer: 7.42 ± 1.783
4.566LeuThr: 4.566 ± 1.65
0.571LeuVal: 0.571 ± 0.801
1.142LeuTrp: 1.142 ± 0.882
4.566LeuTyr: 4.566 ± 2.286
0.0LeuXaa: 0.0 ± 0.0
Met
1.142MetAla: 1.142 ± 0.827
1.712MetCys: 1.712 ± 0.945
1.142MetAsp: 1.142 ± 0.611
0.0MetGlu: 0.0 ± 0.0
1.142MetPhe: 1.142 ± 0.787
1.142MetGly: 1.142 ± 0.559
0.0MetHis: 0.0 ± 0.0
1.142MetIle: 1.142 ± 0.882
2.854MetLys: 2.854 ± 0.764
3.425MetLeu: 3.425 ± 2.261
0.571MetMet: 0.571 ± 0.615
0.571MetAsn: 0.571 ± 0.414
2.283MetPro: 2.283 ± 0.842
1.142MetGln: 1.142 ± 0.559
0.0MetArg: 0.0 ± 0.0
3.425MetSer: 3.425 ± 0.592
0.571MetThr: 0.571 ± 0.414
0.571MetVal: 0.571 ± 0.441
0.0MetTrp: 0.0 ± 0.0
0.571MetTyr: 0.571 ± 0.414
0.0MetXaa: 0.0 ± 0.0
Asn
6.279AsnAla: 6.279 ± 1.914
1.142AsnCys: 1.142 ± 0.827
3.425AsnAsp: 3.425 ± 1.146
3.425AsnGlu: 3.425 ± 1.008
0.571AsnPhe: 0.571 ± 0.801
2.854AsnGly: 2.854 ± 1.277
1.142AsnHis: 1.142 ± 0.611
2.854AsnIle: 2.854 ± 0.651
4.566AsnLys: 4.566 ± 0.941
6.279AsnLeu: 6.279 ± 1.512
1.142AsnMet: 1.142 ± 0.827
2.283AsnAsn: 2.283 ± 0.767
1.142AsnPro: 1.142 ± 0.559
2.854AsnGln: 2.854 ± 2.298
3.425AsnArg: 3.425 ± 0.961
2.283AsnSer: 2.283 ± 1.037
5.708AsnThr: 5.708 ± 1.054
2.283AsnVal: 2.283 ± 1.118
1.142AsnTrp: 1.142 ± 0.827
1.142AsnTyr: 1.142 ± 0.787
0.0AsnXaa: 0.0 ± 0.0
Pro
1.712ProAla: 1.712 ± 0.296
0.571ProCys: 0.571 ± 0.441
3.995ProAsp: 3.995 ± 1.073
4.566ProGlu: 4.566 ± 1.503
1.712ProPhe: 1.712 ± 0.714
1.142ProGly: 1.142 ± 0.611
2.283ProHis: 2.283 ± 0.956
3.425ProIle: 3.425 ± 1.323
1.142ProLys: 1.142 ± 0.882
5.137ProLeu: 5.137 ± 1.666
1.712ProMet: 1.712 ± 0.658
0.571ProAsn: 0.571 ± 0.441
0.571ProPro: 0.571 ± 0.441
1.142ProGln: 1.142 ± 0.772
1.142ProArg: 1.142 ± 0.382
4.566ProSer: 4.566 ± 2.097
3.425ProThr: 3.425 ± 1.326
1.712ProVal: 1.712 ± 0.296
0.571ProTrp: 0.571 ± 0.441
1.712ProTyr: 1.712 ± 0.663
0.0ProXaa: 0.0 ± 0.0
Gln
0.571GlnAla: 0.571 ± 0.615
0.0GlnCys: 0.0 ± 0.0
1.142GlnAsp: 1.142 ± 0.611
1.712GlnGlu: 1.712 ± 0.871
1.142GlnPhe: 1.142 ± 0.827
3.995GlnGly: 3.995 ± 1.323
0.0GlnHis: 0.0 ± 0.0
2.854GlnIle: 2.854 ± 0.867
6.279GlnLys: 6.279 ± 2.056
3.425GlnLeu: 3.425 ± 1.499
0.571GlnMet: 0.571 ± 0.615
1.712GlnAsn: 1.712 ± 0.296
0.571GlnPro: 0.571 ± 0.441
2.283GlnGln: 2.283 ± 0.887
1.712GlnArg: 1.712 ± 1.241
3.425GlnSer: 3.425 ± 1.133
0.0GlnThr: 0.0 ± 0.0
1.712GlnVal: 1.712 ± 1.101
1.142GlnTrp: 1.142 ± 0.867
2.854GlnTyr: 2.854 ± 1.395
0.0GlnXaa: 0.0 ± 0.0
Arg
3.425ArgAla: 3.425 ± 0.868
1.142ArgCys: 1.142 ± 0.882
2.283ArgAsp: 2.283 ± 0.751
0.571ArgGlu: 0.571 ± 0.414
3.425ArgPhe: 3.425 ± 1.326
4.566ArgGly: 4.566 ± 1.84
0.0ArgHis: 0.0 ± 0.0
1.142ArgIle: 1.142 ± 0.827
2.854ArgLys: 2.854 ± 0.736
5.137ArgLeu: 5.137 ± 1.69
0.571ArgMet: 0.571 ± 0.441
2.283ArgAsn: 2.283 ± 0.502
2.854ArgPro: 2.854 ± 1.551
2.283ArgGln: 2.283 ± 1.299
1.712ArgArg: 1.712 ± 0.714
2.854ArgSer: 2.854 ± 0.736
1.142ArgThr: 1.142 ± 1.138
1.142ArgVal: 1.142 ± 0.882
0.0ArgTrp: 0.0 ± 0.0
5.137ArgTyr: 5.137 ± 1.731
0.0ArgXaa: 0.0 ± 0.0
Ser
6.849SerAla: 6.849 ± 4.958
2.854SerCys: 2.854 ± 1.591
5.708SerAsp: 5.708 ± 2.0
1.712SerGlu: 1.712 ± 1.145
1.142SerPhe: 1.142 ± 0.827
4.566SerGly: 4.566 ± 2.718
0.571SerHis: 0.571 ± 0.441
5.708SerIle: 5.708 ± 1.734
6.279SerLys: 6.279 ± 2.175
9.132SerLeu: 9.132 ± 1.495
2.854SerMet: 2.854 ± 0.776
4.566SerAsn: 4.566 ± 1.851
2.283SerPro: 2.283 ± 1.037
1.712SerGln: 1.712 ± 0.767
2.854SerArg: 2.854 ± 1.585
7.991SerSer: 7.991 ± 4.876
6.849SerThr: 6.849 ± 2.986
5.137SerVal: 5.137 ± 1.453
2.283SerTrp: 2.283 ± 1.124
5.137SerTyr: 5.137 ± 2.549
0.0SerXaa: 0.0 ± 0.0
Thr
5.137ThrAla: 5.137 ± 1.817
0.571ThrCys: 0.571 ± 0.441
1.142ThrAsp: 1.142 ± 0.738
1.712ThrGlu: 1.712 ± 0.714
1.712ThrPhe: 1.712 ± 0.663
7.42ThrGly: 7.42 ± 1.046
1.142ThrHis: 1.142 ± 0.867
3.995ThrIle: 3.995 ± 0.822
1.142ThrLys: 1.142 ± 0.382
5.137ThrLeu: 5.137 ± 0.79
0.0ThrMet: 0.0 ± 0.0
3.995ThrAsn: 3.995 ± 0.888
2.854ThrPro: 2.854 ± 1.433
0.571ThrGln: 0.571 ± 0.441
1.712ThrArg: 1.712 ± 0.663
2.283ThrSer: 2.283 ± 1.098
1.142ThrThr: 1.142 ± 0.827
2.854ThrVal: 2.854 ± 1.585
0.571ThrTrp: 0.571 ± 0.414
5.137ThrTyr: 5.137 ± 1.665
0.0ThrXaa: 0.0 ± 0.0
Val
1.142ValAla: 1.142 ± 0.611
0.0ValCys: 0.0 ± 0.0
3.425ValAsp: 3.425 ± 1.025
1.142ValGlu: 1.142 ± 0.787
2.283ValPhe: 2.283 ± 0.502
2.283ValGly: 2.283 ± 0.887
0.571ValHis: 0.571 ± 0.801
3.425ValIle: 3.425 ± 0.517
2.854ValLys: 2.854 ± 0.778
5.137ValLeu: 5.137 ± 2.093
1.142ValMet: 1.142 ± 0.827
6.279ValAsn: 6.279 ± 2.056
4.566ValPro: 4.566 ± 1.464
1.712ValGln: 1.712 ± 0.663
2.283ValArg: 2.283 ± 1.098
6.849ValSer: 6.849 ± 2.912
3.425ValThr: 3.425 ± 0.65
3.425ValVal: 3.425 ± 1.7
0.571ValTrp: 0.571 ± 0.441
2.283ValTyr: 2.283 ± 0.502
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.571TrpAsp: 0.571 ± 0.414
0.571TrpGlu: 0.571 ± 0.441
1.142TrpPhe: 1.142 ± 0.882
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.142TrpIle: 1.142 ± 0.867
1.712TrpLys: 1.712 ± 1.324
1.712TrpLeu: 1.712 ± 0.714
0.571TrpMet: 0.571 ± 0.414
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.571TrpGln: 0.571 ± 0.441
1.142TrpArg: 1.142 ± 0.382
1.142TrpSer: 1.142 ± 0.882
1.712TrpThr: 1.712 ± 1.241
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.283TyrAla: 2.283 ± 0.767
2.854TyrCys: 2.854 ± 1.551
2.283TyrAsp: 2.283 ± 0.764
2.283TyrGlu: 2.283 ± 0.842
3.425TyrPhe: 3.425 ± 1.326
1.712TyrGly: 1.712 ± 0.714
1.712TyrHis: 1.712 ± 1.324
3.425TyrIle: 3.425 ± 1.035
5.137TyrLys: 5.137 ± 1.077
4.566TyrLeu: 4.566 ± 1.65
2.283TyrMet: 2.283 ± 1.124
2.854TyrAsn: 2.854 ± 0.991
1.142TyrPro: 1.142 ± 0.827
2.854TyrGln: 2.854 ± 1.438
2.283TyrArg: 2.283 ± 0.764
2.283TyrSer: 2.283 ± 0.767
5.137TyrThr: 5.137 ± 1.331
2.854TyrVal: 2.854 ± 0.298
0.0TyrTrp: 0.0 ± 0.0
1.712TyrTyr: 1.712 ± 0.959
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1753 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski