Amino acid dipepetide frequency for Cordyceps fumosorosea (strain ARSEF 2679) (Isaria fumosorosea)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.03AlaAla: 14.03 ± 0.099	1.233AlaCys: 1.233 ± 0.018	5.368AlaAsp: 5.368 ± 0.039	5.807AlaGlu: 5.807 ± 0.053	3.296AlaPhe: 3.296 ± 0.029	7.278AlaGly: 7.278 ± 0.053	2.102AlaHis: 2.102 ± 0.022	4.136AlaIle: 4.136 ± 0.037	4.303AlaLys: 4.303 ± 0.043	8.956AlaLeu: 8.956 ± 0.055	2.255AlaMet: 2.255 ± 0.024	3.006AlaAsn: 3.006 ± 0.026	5.652AlaPro: 5.652 ± 0.048	3.72AlaGln: 3.72 ± 0.031	6.213AlaArg: 6.213 ± 0.052	7.923AlaSer: 7.923 ± 0.051	6.192AlaThr: 6.192 ± 0.043	6.721AlaVal: 6.721 ± 0.044	1.355AlaTrp: 1.355 ± 0.019	2.268AlaTyr: 2.268 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	1.103CysAla: 1.103 ± 0.018	0.247CysCys: 0.247 ± 0.008	0.689CysAsp: 0.689 ± 0.014	0.581CysGlu: 0.581 ± 0.011	0.526CysPhe: 0.526 ± 0.012	0.987CysGly: 0.987 ± 0.016	0.315CysHis: 0.315 ± 0.009	0.626CysIle: 0.626 ± 0.011	0.495CysLys: 0.495 ± 0.012	1.255CysLeu: 1.255 ± 0.016	0.269CysMet: 0.269 ± 0.009	0.401CysAsn: 0.401 ± 0.012	0.674CysPro: 0.674 ± 0.015	0.435CysGln: 0.435 ± 0.01	0.813CysArg: 0.813 ± 0.014	0.842CysSer: 0.842 ± 0.015	0.678CysThr: 0.678 ± 0.012	0.845CysVal: 0.845 ± 0.015	0.197CysTrp: 0.197 ± 0.006	0.338CysTyr: 0.338 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.002AspAla: 6.002 ± 0.046	0.667AspCys: 0.667 ± 0.014	4.951AspAsp: 4.951 ± 0.053	4.723AspGlu: 4.723 ± 0.044	2.172AspPhe: 2.172 ± 0.023	4.817AspGly: 4.817 ± 0.036	1.182AspHis: 1.182 ± 0.017	2.642AspIle: 2.642 ± 0.021	2.512AspLys: 2.512 ± 0.026	4.826AspLeu: 4.826 ± 0.036	1.374AspMet: 1.374 ± 0.017	1.831AspAsn: 1.831 ± 0.024	3.114AspPro: 3.114 ± 0.03	1.735AspGln: 1.735 ± 0.021	3.234AspArg: 3.234 ± 0.033	3.914AspSer: 3.914 ± 0.033	2.868AspThr: 2.868 ± 0.025	3.931AspVal: 3.931 ± 0.031	0.88AspTrp: 0.88 ± 0.015	1.515AspTyr: 1.515 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	6.107GluAla: 6.107 ± 0.051	0.595GluCys: 0.595 ± 0.012	4.081GluAsp: 4.081 ± 0.044	5.253GluGlu: 5.253 ± 0.071	1.847GluPhe: 1.847 ± 0.02	3.533GluGly: 3.533 ± 0.028	1.384GluHis: 1.384 ± 0.017	2.494GluIle: 2.494 ± 0.023	3.106GluLys: 3.106 ± 0.039	5.155GluLeu: 5.155 ± 0.039	1.479GluMet: 1.479 ± 0.018	1.947GluAsn: 1.947 ± 0.025	2.905GluPro: 2.905 ± 0.041	2.436GluGln: 2.436 ± 0.029	3.981GluArg: 3.981 ± 0.033	3.795GluSer: 3.795 ± 0.029	3.317GluThr: 3.317 ± 0.027	3.444GluVal: 3.444 ± 0.033	0.816GluTrp: 0.816 ± 0.014	1.546GluTyr: 1.546 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.369PheAla: 3.369 ± 0.032	0.549PheCys: 0.549 ± 0.011	2.266PheAsp: 2.266 ± 0.024	1.97PheGlu: 1.97 ± 0.02	1.566PhePhe: 1.566 ± 0.022	2.811PheGly: 2.811 ± 0.031	0.856PheHis: 0.856 ± 0.014	1.557PheIle: 1.557 ± 0.02	1.358PheLys: 1.358 ± 0.018	3.311PheLeu: 3.311 ± 0.033	0.764PheMet: 0.764 ± 0.012	1.297PheAsn: 1.297 ± 0.017	1.776PhePro: 1.776 ± 0.02	1.279PheGln: 1.279 ± 0.019	2.001PheArg: 2.001 ± 0.021	2.695PheSer: 2.695 ± 0.023	1.986PheThr: 1.986 ± 0.019	2.405PheVal: 2.405 ± 0.024	0.625PheTrp: 0.625 ± 0.013	1.062PheTyr: 1.062 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	6.622GlyAla: 6.622 ± 0.046	0.915GlyCys: 0.915 ± 0.016	4.057GlyAsp: 4.057 ± 0.03	3.788GlyGlu: 3.788 ± 0.028	2.735GlyPhe: 2.735 ± 0.025	7.147GlyGly: 7.147 ± 0.068	1.765GlyHis: 1.765 ± 0.021	3.247GlyIle: 3.247 ± 0.028	3.378GlyLys: 3.378 ± 0.034	6.138GlyLeu: 6.138 ± 0.042	1.625GlyMet: 1.625 ± 0.02	2.498GlyAsn: 2.498 ± 0.037	3.486GlyPro: 3.486 ± 0.046	2.617GlyGln: 2.617 ± 0.026	4.76GlyArg: 4.76 ± 0.035	5.773GlySer: 5.773 ± 0.042	4.032GlyThr: 4.032 ± 0.037	4.667GlyVal: 4.667 ± 0.036	1.209GlyTrp: 1.209 ± 0.017	2.123GlyTyr: 2.123 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	2.159HisAla: 2.159 ± 0.024	0.327HisCys: 0.327 ± 0.009	1.415HisAsp: 1.415 ± 0.017	1.276HisGlu: 1.276 ± 0.019	0.877HisPhe: 0.877 ± 0.014	1.862HisGly: 1.862 ± 0.021	0.943HisHis: 0.943 ± 0.022	1.071HisIle: 1.071 ± 0.016	0.84HisLys: 0.84 ± 0.013	2.175HisLeu: 2.175 ± 0.024	0.518HisMet: 0.518 ± 0.011	0.782HisAsn: 0.782 ± 0.014	1.587HisPro: 1.587 ± 0.02	0.973HisGln: 0.973 ± 0.019	1.652HisArg: 1.652 ± 0.023	1.643HisSer: 1.643 ± 0.023	1.129HisThr: 1.129 ± 0.014	1.558HisVal: 1.558 ± 0.018	0.343HisTrp: 0.343 ± 0.007	0.648HisTyr: 0.648 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.087IleAla: 4.087 ± 0.03	0.647IleCys: 0.647 ± 0.012	2.606IleAsp: 2.606 ± 0.023	2.424IleGlu: 2.424 ± 0.026	1.701IlePhe: 1.701 ± 0.02	2.94IleGly: 2.94 ± 0.032	1.028IleHis: 1.028 ± 0.015	2.156IleIle: 2.156 ± 0.047	1.916IleLys: 1.916 ± 0.024	4.024IleLeu: 4.024 ± 0.034	0.97IleMet: 0.97 ± 0.013	1.531IleAsn: 1.531 ± 0.018	2.595IlePro: 2.595 ± 0.023	1.598IleGln: 1.598 ± 0.02	2.556IleArg: 2.556 ± 0.026	3.17IleSer: 3.17 ± 0.028	2.484IleThr: 2.484 ± 0.027	2.986IleVal: 2.986 ± 0.028	0.613IleTrp: 0.613 ± 0.012	1.167IleTyr: 1.167 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.275LysAla: 4.275 ± 0.038	0.446LysCys: 0.446 ± 0.009	2.581LysAsp: 2.581 ± 0.027	2.909LysGlu: 2.909 ± 0.034	1.343LysPhe: 1.343 ± 0.016	2.687LysGly: 2.687 ± 0.03	0.999LysHis: 0.999 ± 0.015	1.945LysIle: 1.945 ± 0.021	3.06LysLys: 3.06 ± 0.055	3.897LysLeu: 3.897 ± 0.035	1.027LysMet: 1.027 ± 0.015	1.528LysAsn: 1.528 ± 0.022	2.562LysPro: 2.562 ± 0.03	1.806LysGln: 1.806 ± 0.019	3.142LysArg: 3.142 ± 0.034	3.129LysSer: 3.129 ± 0.031	2.76LysThr: 2.76 ± 0.026	2.569LysVal: 2.569 ± 0.029	0.587LysTrp: 0.587 ± 0.012	1.21LysTyr: 1.21 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	9.166LeuAla: 9.166 ± 0.051	1.227LeuCys: 1.227 ± 0.016	5.277LeuAsp: 5.277 ± 0.039	5.108LeuGlu: 5.108 ± 0.045	3.256LeuPhe: 3.256 ± 0.034	6.111LeuGly: 6.111 ± 0.039	2.212LeuHis: 2.212 ± 0.023	3.485LeuIle: 3.485 ± 0.031	3.626LeuLys: 3.626 ± 0.029	8.558LeuLeu: 8.558 ± 0.069	1.756LeuMet: 1.756 ± 0.021	2.788LeuAsn: 2.788 ± 0.029	5.589LeuPro: 5.589 ± 0.038	3.729LeuGln: 3.729 ± 0.033	6.259LeuArg: 6.259 ± 0.049	6.737LeuSer: 6.737 ± 0.046	4.676LeuThr: 4.676 ± 0.037	5.736LeuVal: 5.736 ± 0.041	1.233LeuTrp: 1.233 ± 0.02	2.228LeuTyr: 2.228 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.505MetAla: 2.505 ± 0.021	0.245MetCys: 0.245 ± 0.007	1.297MetAsp: 1.297 ± 0.018	1.224MetGlu: 1.224 ± 0.018	0.711MetPhe: 0.711 ± 0.013	1.46MetGly: 1.46 ± 0.021	0.506MetHis: 0.506 ± 0.011	0.89MetIle: 0.89 ± 0.015	0.929MetLys: 0.929 ± 0.015	1.933MetLeu: 1.933 ± 0.018	0.596MetMet: 0.596 ± 0.012	0.721MetAsn: 0.721 ± 0.013	1.419MetPro: 1.419 ± 0.02	0.895MetGln: 0.895 ± 0.016	1.399MetArg: 1.399 ± 0.02	1.784MetSer: 1.784 ± 0.021	1.35MetThr: 1.35 ± 0.015	1.335MetVal: 1.335 ± 0.019	0.253MetTrp: 0.253 ± 0.008	0.53MetTyr: 0.53 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.125AsnAla: 3.125 ± 0.025	0.407AsnCys: 0.407 ± 0.01	1.808AsnAsp: 1.808 ± 0.022	1.711AsnGlu: 1.711 ± 0.019	1.224AsnPhe: 1.224 ± 0.017	2.866AsnGly: 2.866 ± 0.034	0.762AsnHis: 0.762 ± 0.014	1.694AsnIle: 1.694 ± 0.021	1.457AsnLys: 1.457 ± 0.021	2.916AsnLeu: 2.916 ± 0.024	0.828AsnMet: 0.828 ± 0.013	1.37AsnAsn: 1.37 ± 0.024	2.134AsnPro: 2.134 ± 0.026	1.157AsnGln: 1.157 ± 0.016	1.798AsnArg: 1.798 ± 0.02	2.316AsnSer: 2.316 ± 0.025	1.918AsnThr: 1.918 ± 0.023	2.165AsnVal: 2.165 ± 0.022	0.504AsnTrp: 0.504 ± 0.011	0.934AsnTyr: 0.934 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	6.361ProAla: 6.361 ± 0.062	0.543ProCys: 0.543 ± 0.013	3.297ProAsp: 3.297 ± 0.029	3.658ProGlu: 3.658 ± 0.035	1.92ProPhe: 1.92 ± 0.024	4.262ProGly: 4.262 ± 0.042	1.27ProHis: 1.27 ± 0.018	2.214ProIle: 2.214 ± 0.024	2.431ProLys: 2.431 ± 0.029	4.699ProLeu: 4.699 ± 0.037	1.064ProMet: 1.064 ± 0.016	1.929ProAsn: 1.929 ± 0.02	5.624ProPro: 5.624 ± 0.081	2.388ProGln: 2.388 ± 0.032	3.749ProArg: 3.749 ± 0.032	5.563ProSer: 5.563 ± 0.043	3.823ProThr: 3.823 ± 0.035	3.746ProVal: 3.746 ± 0.033	0.743ProTrp: 0.743 ± 0.013	1.358ProTyr: 1.358 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.65GlnAla: 3.65 ± 0.033	0.423GlnCys: 0.423 ± 0.01	2.09GlnAsp: 2.09 ± 0.021	2.203GlnGlu: 2.203 ± 0.024	1.231GlnPhe: 1.231 ± 0.017	2.429GlnGly: 2.429 ± 0.026	1.17GlnHis: 1.17 ± 0.019	1.619GlnIle: 1.619 ± 0.017	1.73GlnLys: 1.73 ± 0.022	3.497GlnLeu: 3.497 ± 0.029	0.884GlnMet: 0.884 ± 0.017	1.309GlnAsn: 1.309 ± 0.019	2.612GlnPro: 2.612 ± 0.029	2.847GlnGln: 2.847 ± 0.072	2.747GlnArg: 2.747 ± 0.03	2.81GlnSer: 2.81 ± 0.027	2.134GlnThr: 2.134 ± 0.023	2.216GlnVal: 2.216 ± 0.024	0.528GlnTrp: 0.528 ± 0.011	1.079GlnTyr: 1.079 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	5.926ArgAla: 5.926 ± 0.046	0.812ArgCys: 0.812 ± 0.015	3.8ArgAsp: 3.8 ± 0.033	3.86ArgGlu: 3.86 ± 0.036	2.191ArgPhe: 2.191 ± 0.025	4.358ArgGly: 4.358 ± 0.04	1.79ArgHis: 1.79 ± 0.02	2.741ArgIle: 2.741 ± 0.024	3.166ArgLys: 3.166 ± 0.031	5.891ArgLeu: 5.891 ± 0.046	1.369ArgMet: 1.369 ± 0.019	2.088ArgAsn: 2.088 ± 0.021	3.796ArgPro: 3.796 ± 0.034	2.762ArgGln: 2.762 ± 0.025	6.126ArgArg: 6.126 ± 0.051	4.712ArgSer: 4.712 ± 0.04	3.273ArgThr: 3.273 ± 0.03	3.762ArgVal: 3.762 ± 0.029	1.01ArgTrp: 1.01 ± 0.017	1.635ArgTyr: 1.635 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	7.169SerAla: 7.169 ± 0.042	0.842SerCys: 0.842 ± 0.016	4.021SerAsp: 4.021 ± 0.036	3.675SerGlu: 3.675 ± 0.033	2.746SerPhe: 2.746 ± 0.028	5.555SerGly: 5.555 ± 0.038	1.787SerHis: 1.787 ± 0.021	3.397SerIle: 3.397 ± 0.033	3.339SerLys: 3.339 ± 0.032	6.671SerLeu: 6.671 ± 0.046	1.661SerMet: 1.661 ± 0.021	2.554SerAsn: 2.554 ± 0.026	5.148SerPro: 5.148 ± 0.046	2.947SerGln: 2.947 ± 0.029	4.956SerArg: 4.956 ± 0.042	8.308SerSer: 8.308 ± 0.083	5.031SerThr: 5.031 ± 0.059	4.524SerVal: 4.524 ± 0.033	1.057SerTrp: 1.057 ± 0.014	1.841SerTyr: 1.841 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	6.012ThrAla: 6.012 ± 0.038	0.718ThrCys: 0.718 ± 0.014	2.792ThrAsp: 2.792 ± 0.027	2.986ThrGlu: 2.986 ± 0.03	2.079ThrPhe: 2.079 ± 0.022	4.227ThrGly: 4.227 ± 0.048	1.223ThrHis: 1.223 ± 0.016	2.703ThrIle: 2.703 ± 0.029	2.421ThrLys: 2.421 ± 0.024	5.074ThrLeu: 5.074 ± 0.036	1.184ThrMet: 1.184 ± 0.015	1.852ThrAsn: 1.852 ± 0.023	4.194ThrPro: 4.194 ± 0.045	1.955ThrGln: 1.955 ± 0.023	3.208ThrArg: 3.208 ± 0.024	4.859ThrSer: 4.859 ± 0.045	4.466ThrThr: 4.466 ± 0.051	3.86ThrVal: 3.86 ± 0.03	0.809ThrTrp: 0.809 ± 0.015	1.459ThrTyr: 1.459 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	6.578ValAla: 6.578 ± 0.046	0.872ValCys: 0.872 ± 0.014	3.971ValAsp: 3.971 ± 0.031	3.836ValGlu: 3.836 ± 0.037	2.463ValPhe: 2.463 ± 0.027	4.314ValGly: 4.314 ± 0.036	1.423ValHis: 1.423 ± 0.018	2.733ValIle: 2.733 ± 0.027	2.662ValLys: 2.662 ± 0.028	5.932ValLeu: 5.932 ± 0.047	1.367ValMet: 1.367 ± 0.018	2.088ValAsn: 2.088 ± 0.022	3.797ValPro: 3.797 ± 0.03	2.348ValGln: 2.348 ± 0.021	3.875ValArg: 3.875 ± 0.03	4.477ValSer: 4.477 ± 0.033	3.618ValThr: 3.618 ± 0.029	4.838ValVal: 4.838 ± 0.037	0.899ValTrp: 0.899 ± 0.013	1.737ValTyr: 1.737 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.26TrpAla: 1.26 ± 0.017	0.205TrpCys: 0.205 ± 0.007	0.895TrpAsp: 0.895 ± 0.015	0.794TrpGlu: 0.794 ± 0.014	0.522TrpPhe: 0.522 ± 0.011	0.931TrpGly: 0.931 ± 0.016	0.362TrpHis: 0.362 ± 0.01	0.68TrpIle: 0.68 ± 0.013	0.675TrpLys: 0.675 ± 0.011	1.392TrpLeu: 1.392 ± 0.024	0.367TrpMet: 0.367 ± 0.009	0.569TrpAsn: 0.569 ± 0.011	0.627TrpPro: 0.627 ± 0.011	0.584TrpGln: 0.584 ± 0.011	1.034TrpArg: 1.034 ± 0.016	1.006TrpSer: 1.006 ± 0.017	0.884TrpThr: 0.884 ± 0.014	0.875TrpVal: 0.875 ± 0.014	0.282TrpTrp: 0.282 ± 0.008	0.418TrpTyr: 0.418 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.305TyrAla: 2.305 ± 0.024	0.398TyrCys: 0.398 ± 0.01	1.626TyrAsp: 1.626 ± 0.019	1.434TyrGlu: 1.434 ± 0.02	1.097TyrPhe: 1.097 ± 0.018	2.006TyrGly: 2.006 ± 0.024	0.701TyrHis: 0.701 ± 0.014	1.17TyrIle: 1.17 ± 0.016	1.061TyrLys: 1.061 ± 0.017	2.457TyrLeu: 2.457 ± 0.023	0.628TyrMet: 0.628 ± 0.012	1.005TyrAsn: 1.005 ± 0.014	1.349TyrPro: 1.349 ± 0.018	0.999TyrGln: 0.999 ± 0.017	1.565TyrArg: 1.565 ± 0.019	1.773TyrSer: 1.773 ± 0.021	1.461TyrThr: 1.461 ± 0.019	1.643TyrVal: 1.643 ± 0.017	0.421TyrTrp: 0.421 ± 0.009	0.883TyrTyr: 0.883 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10050 proteins (4864145 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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