Amino acid dipepetide frequency for La Piedad-Michoacan-Mexico virus (LPMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.642AlaAla: 7.642 ± 2.078
1.337AlaCys: 1.337 ± 0.451
2.675AlaAsp: 2.675 ± 0.527
2.866AlaGlu: 2.866 ± 0.539
1.72AlaPhe: 1.72 ± 0.727
5.35AlaGly: 5.35 ± 0.615
1.337AlaHis: 1.337 ± 0.433
5.732AlaIle: 5.732 ± 1.073
2.675AlaLys: 2.675 ± 0.962
9.362AlaLeu: 9.362 ± 2.507
2.675AlaMet: 2.675 ± 1.473
3.248AlaAsn: 3.248 ± 0.44
6.114AlaPro: 6.114 ± 3.017
4.012AlaGln: 4.012 ± 0.683
5.732AlaArg: 5.732 ± 2.278
4.585AlaSer: 4.585 ± 0.902
4.776AlaThr: 4.776 ± 1.582
3.248AlaVal: 3.248 ± 1.109
0.573AlaTrp: 0.573 ± 0.26
2.484AlaTyr: 2.484 ± 0.562
0.0AlaXaa: 0.0 ± 0.0
Cys
2.293CysAla: 2.293 ± 0.698
0.191CysCys: 0.191 ± 0.129
0.382CysAsp: 0.382 ± 0.186
0.573CysGlu: 0.573 ± 0.279
0.955CysPhe: 0.955 ± 0.462
1.146CysGly: 1.146 ± 0.503
0.382CysHis: 0.382 ± 0.329
0.764CysIle: 0.764 ± 0.258
0.573CysLys: 0.573 ± 0.26
2.484CysLeu: 2.484 ± 1.087
0.382CysMet: 0.382 ± 0.301
0.382CysAsn: 0.382 ± 0.309
1.911CysPro: 1.911 ± 1.312
1.146CysGln: 1.146 ± 0.59
0.191CysArg: 0.191 ± 0.201
1.337CysSer: 1.337 ± 0.504
0.955CysThr: 0.955 ± 0.553
1.146CysVal: 1.146 ± 0.4
0.0CysTrp: 0.0 ± 0.0
0.764CysTyr: 0.764 ± 0.475
0.0CysXaa: 0.0 ± 0.0
Asp
2.484AspAla: 2.484 ± 0.85
0.382AspCys: 0.382 ± 0.237
1.337AspAsp: 1.337 ± 0.674
3.439AspGlu: 3.439 ± 0.85
1.72AspPhe: 1.72 ± 0.717
4.012AspGly: 4.012 ± 1.126
0.573AspHis: 0.573 ± 0.493
2.484AspIle: 2.484 ± 0.946
1.146AspLys: 1.146 ± 0.404
5.541AspLeu: 5.541 ± 1.169
0.955AspMet: 0.955 ± 0.65
1.72AspAsn: 1.72 ± 0.609
5.541AspPro: 5.541 ± 1.169
2.484AspGln: 2.484 ± 0.451
2.675AspArg: 2.675 ± 0.652
1.911AspSer: 1.911 ± 0.564
2.675AspThr: 2.675 ± 0.532
1.337AspVal: 1.337 ± 0.475
0.764AspTrp: 0.764 ± 0.442
0.764AspTyr: 0.764 ± 0.348
0.0AspXaa: 0.0 ± 0.0
Glu
2.102GluAla: 2.102 ± 0.6
0.764GluCys: 0.764 ± 0.313
1.72GluAsp: 1.72 ± 0.727
3.821GluGlu: 3.821 ± 1.012
1.146GluPhe: 1.146 ± 0.425
4.012GluGly: 4.012 ± 1.555
0.764GluHis: 0.764 ± 0.348
4.394GluIle: 4.394 ± 0.426
1.911GluLys: 1.911 ± 0.76
6.878GluLeu: 6.878 ± 1.749
0.955GluMet: 0.955 ± 0.263
2.675GluAsn: 2.675 ± 0.869
1.528GluPro: 1.528 ± 0.765
2.675GluGln: 2.675 ± 0.8
4.394GluArg: 4.394 ± 1.102
4.585GluSer: 4.585 ± 1.167
3.248GluThr: 3.248 ± 0.589
4.203GluVal: 4.203 ± 1.214
0.573GluTrp: 0.573 ± 0.307
2.102GluTyr: 2.102 ± 0.625
0.0GluXaa: 0.0 ± 0.0
Phe
3.057PheAla: 3.057 ± 0.792
0.573PheCys: 0.573 ± 0.242
1.528PheAsp: 1.528 ± 0.611
2.102PheGlu: 2.102 ± 0.615
1.528PhePhe: 1.528 ± 0.59
1.72PheGly: 1.72 ± 0.502
0.955PheHis: 0.955 ± 0.643
2.102PheIle: 2.102 ± 1.095
1.337PheLys: 1.337 ± 0.482
3.248PheLeu: 3.248 ± 0.813
1.337PheMet: 1.337 ± 0.431
1.337PheAsn: 1.337 ± 0.423
0.764PhePro: 0.764 ± 0.28
1.72PheGln: 1.72 ± 0.634
1.72PheArg: 1.72 ± 0.543
3.248PheSer: 3.248 ± 0.537
2.675PheThr: 2.675 ± 0.314
1.528PheVal: 1.528 ± 0.561
0.191PheTrp: 0.191 ± 0.129
0.955PheTyr: 0.955 ± 0.336
0.0PheXaa: 0.0 ± 0.0
Gly
4.776GlyAla: 4.776 ± 1.851
1.337GlyCys: 1.337 ± 0.981
4.776GlyAsp: 4.776 ± 0.856
3.439GlyGlu: 3.439 ± 0.98
1.72GlyPhe: 1.72 ± 0.552
5.541GlyGly: 5.541 ± 2.211
1.146GlyHis: 1.146 ± 0.428
3.439GlyIle: 3.439 ± 0.645
2.675GlyLys: 2.675 ± 0.735
6.496GlyLeu: 6.496 ± 0.663
0.764GlyMet: 0.764 ± 0.237
2.484GlyAsn: 2.484 ± 0.939
3.821GlyPro: 3.821 ± 1.414
2.484GlyGln: 2.484 ± 0.927
3.057GlyArg: 3.057 ± 0.48
6.687GlySer: 6.687 ± 2.285
3.821GlyThr: 3.821 ± 0.962
4.012GlyVal: 4.012 ± 1.034
0.573GlyTrp: 0.573 ± 0.444
0.955GlyTyr: 0.955 ± 0.38
0.0GlyXaa: 0.0 ± 0.0
His
0.955HisAla: 0.955 ± 0.497
0.764HisCys: 0.764 ± 0.828
1.337HisAsp: 1.337 ± 0.669
0.955HisGlu: 0.955 ± 0.454
0.382HisPhe: 0.382 ± 0.257
0.191HisGly: 0.191 ± 0.129
0.764HisHis: 0.764 ± 0.442
0.764HisIle: 0.764 ± 0.33
0.764HisLys: 0.764 ± 0.514
3.439HisLeu: 3.439 ± 0.981
0.191HisMet: 0.191 ± 0.201
0.955HisAsn: 0.955 ± 0.306
2.102HisPro: 2.102 ± 0.704
0.573HisGln: 0.573 ± 0.34
1.337HisArg: 1.337 ± 0.453
1.337HisSer: 1.337 ± 0.406
1.146HisThr: 1.146 ± 0.392
1.337HisVal: 1.337 ± 0.347
0.573HisTrp: 0.573 ± 0.269
0.191HisTyr: 0.191 ± 0.129
0.0HisXaa: 0.0 ± 0.0
Ile
4.776IleAla: 4.776 ± 0.774
0.191IleCys: 0.191 ± 0.209
2.484IleAsp: 2.484 ± 0.69
4.585IleGlu: 4.585 ± 1.022
2.293IlePhe: 2.293 ± 0.645
3.439IleGly: 3.439 ± 0.561
1.337IleHis: 1.337 ± 0.445
4.012IleIle: 4.012 ± 1.432
2.675IleLys: 2.675 ± 0.756
6.496IleLeu: 6.496 ± 1.458
1.146IleMet: 1.146 ± 0.636
3.057IleAsn: 3.057 ± 0.759
3.63IlePro: 3.63 ± 1.169
3.821IleGln: 3.821 ± 0.618
3.057IleArg: 3.057 ± 0.733
6.114IleSer: 6.114 ± 1.713
4.968IleThr: 4.968 ± 1.358
2.866IleVal: 2.866 ± 0.49
0.764IleTrp: 0.764 ± 0.357
2.102IleTyr: 2.102 ± 0.594
0.0IleXaa: 0.0 ± 0.0
Lys
2.102LysAla: 2.102 ± 0.744
0.764LysCys: 0.764 ± 0.331
0.955LysAsp: 0.955 ± 0.497
2.102LysGlu: 2.102 ± 0.703
2.293LysPhe: 2.293 ± 0.761
1.72LysGly: 1.72 ± 0.659
0.955LysHis: 0.955 ± 0.643
2.675LysIle: 2.675 ± 1.031
1.911LysLys: 1.911 ± 0.564
2.675LysLeu: 2.675 ± 1.379
0.764LysMet: 0.764 ± 0.629
1.528LysAsn: 1.528 ± 0.661
0.955LysPro: 0.955 ± 0.34
1.337LysGln: 1.337 ± 0.432
3.057LysArg: 3.057 ± 0.813
2.102LysSer: 2.102 ± 0.605
2.484LysThr: 2.484 ± 0.748
3.248LysVal: 3.248 ± 0.881
0.191LysTrp: 0.191 ± 0.209
1.911LysTyr: 1.911 ± 0.606
0.0LysXaa: 0.0 ± 0.0
Leu
7.833LeuAla: 7.833 ± 1.413
2.293LeuCys: 2.293 ± 0.937
4.776LeuAsp: 4.776 ± 1.122
6.687LeuGlu: 6.687 ± 1.279
2.484LeuPhe: 2.484 ± 0.883
7.642LeuGly: 7.642 ± 1.449
1.337LeuHis: 1.337 ± 0.421
6.878LeuIle: 6.878 ± 0.855
5.159LeuLys: 5.159 ± 1.213
9.553LeuLeu: 9.553 ± 1.691
4.203LeuMet: 4.203 ± 1.213
4.968LeuAsn: 4.968 ± 0.798
6.114LeuPro: 6.114 ± 1.704
4.203LeuGln: 4.203 ± 0.81
4.776LeuArg: 4.776 ± 1.179
10.317LeuSer: 10.317 ± 1.399
9.171LeuThr: 9.171 ± 1.627
6.878LeuVal: 6.878 ± 0.948
1.146LeuTrp: 1.146 ± 0.515
2.293LeuTyr: 2.293 ± 0.571
0.0LeuXaa: 0.0 ± 0.0
Met
3.248MetAla: 3.248 ± 1.085
0.382MetCys: 0.382 ± 0.206
1.146MetAsp: 1.146 ± 0.568
1.337MetGlu: 1.337 ± 0.516
0.955MetPhe: 0.955 ± 0.412
0.955MetGly: 0.955 ± 0.503
0.573MetHis: 0.573 ± 0.278
1.72MetIle: 1.72 ± 0.491
0.955MetLys: 0.955 ± 0.323
2.293MetLeu: 2.293 ± 0.876
0.764MetMet: 0.764 ± 0.332
0.573MetAsn: 0.573 ± 0.386
0.573MetPro: 0.573 ± 0.29
0.955MetGln: 0.955 ± 0.282
2.102MetArg: 2.102 ± 0.902
2.293MetSer: 2.293 ± 0.74
1.337MetThr: 1.337 ± 0.345
2.102MetVal: 2.102 ± 0.6
0.382MetTrp: 0.382 ± 0.206
0.764MetTyr: 0.764 ± 0.237
0.0MetXaa: 0.0 ± 0.0
Asn
3.057AsnAla: 3.057 ± 1.184
0.382AsnCys: 0.382 ± 0.196
2.293AsnAsp: 2.293 ± 0.595
1.146AsnGlu: 1.146 ± 0.307
1.911AsnPhe: 1.911 ± 0.418
2.675AsnGly: 2.675 ± 0.415
1.337AsnHis: 1.337 ± 0.514
2.293AsnIle: 2.293 ± 0.826
0.955AsnLys: 0.955 ± 0.307
2.484AsnLeu: 2.484 ± 1.071
0.382AsnMet: 0.382 ± 0.338
0.955AsnAsn: 0.955 ± 0.47
4.776AsnPro: 4.776 ± 1.296
4.394AsnGln: 4.394 ± 0.949
3.248AsnArg: 3.248 ± 0.541
2.102AsnSer: 2.102 ± 0.647
0.955AsnThr: 0.955 ± 0.453
1.337AsnVal: 1.337 ± 0.347
0.573AsnTrp: 0.573 ± 0.386
1.337AsnTyr: 1.337 ± 0.46
0.0AsnXaa: 0.0 ± 0.0
Pro
6.114ProAla: 6.114 ± 2.618
0.191ProCys: 0.191 ± 0.209
2.866ProAsp: 2.866 ± 0.545
3.057ProGlu: 3.057 ± 1.241
1.72ProPhe: 1.72 ± 0.695
6.878ProGly: 6.878 ± 3.099
1.528ProHis: 1.528 ± 0.712
2.675ProIle: 2.675 ± 1.046
1.528ProLys: 1.528 ± 0.764
8.789ProLeu: 8.789 ± 1.963
0.573ProMet: 0.573 ± 0.279
2.293ProAsn: 2.293 ± 0.756
3.439ProPro: 3.439 ± 0.925
3.63ProGln: 3.63 ± 1.09
2.866ProArg: 2.866 ± 1.201
2.675ProSer: 2.675 ± 1.088
6.878ProThr: 6.878 ± 2.335
4.012ProVal: 4.012 ± 0.933
0.382ProTrp: 0.382 ± 0.225
2.102ProTyr: 2.102 ± 0.631
0.0ProXaa: 0.0 ± 0.0
Gln
3.821GlnAla: 3.821 ± 1.198
0.955GlnCys: 0.955 ± 0.467
2.293GlnAsp: 2.293 ± 0.71
3.248GlnGlu: 3.248 ± 0.65
2.293GlnPhe: 2.293 ± 0.934
2.675GlnGly: 2.675 ± 0.504
0.955GlnHis: 0.955 ± 0.67
3.439GlnIle: 3.439 ± 1.404
1.72GlnLys: 1.72 ± 0.609
5.541GlnLeu: 5.541 ± 1.558
0.955GlnMet: 0.955 ± 0.282
1.337GlnAsn: 1.337 ± 0.752
3.63GlnPro: 3.63 ± 1.095
2.293GlnGln: 2.293 ± 0.576
2.675GlnArg: 2.675 ± 0.6
3.63GlnSer: 3.63 ± 1.231
2.102GlnThr: 2.102 ± 0.771
3.248GlnVal: 3.248 ± 0.838
0.382GlnTrp: 0.382 ± 0.257
1.337GlnTyr: 1.337 ± 0.467
0.0GlnXaa: 0.0 ± 0.0
Arg
4.012ArgAla: 4.012 ± 0.837
0.955ArgCys: 0.955 ± 0.451
3.057ArgAsp: 3.057 ± 0.818
1.911ArgGlu: 1.911 ± 0.367
1.528ArgPhe: 1.528 ± 0.469
4.394ArgGly: 4.394 ± 1.758
1.146ArgHis: 1.146 ± 0.653
3.821ArgIle: 3.821 ± 0.761
3.439ArgLys: 3.439 ± 0.67
6.687ArgLeu: 6.687 ± 1.691
2.102ArgMet: 2.102 ± 0.876
1.528ArgAsn: 1.528 ± 0.401
3.439ArgPro: 3.439 ± 1.174
2.293ArgGln: 2.293 ± 0.733
3.63ArgArg: 3.63 ± 0.945
4.012ArgSer: 4.012 ± 1.119
2.866ArgThr: 2.866 ± 0.477
4.203ArgVal: 4.203 ± 1.12
1.146ArgTrp: 1.146 ± 0.59
1.72ArgTyr: 1.72 ± 0.705
0.0ArgXaa: 0.0 ± 0.0
Ser
5.35SerAla: 5.35 ± 0.746
2.675SerCys: 2.675 ± 0.641
3.63SerAsp: 3.63 ± 0.716
4.585SerGlu: 4.585 ± 1.495
2.102SerPhe: 2.102 ± 0.504
3.821SerGly: 3.821 ± 0.674
1.528SerHis: 1.528 ± 0.515
5.35SerIle: 5.35 ± 1.051
1.337SerLys: 1.337 ± 0.531
7.069SerLeu: 7.069 ± 1.239
1.911SerMet: 1.911 ± 0.655
3.248SerAsn: 3.248 ± 0.757
4.012SerPro: 4.012 ± 0.85
2.675SerGln: 2.675 ± 0.561
3.821SerArg: 3.821 ± 1.146
6.878SerSer: 6.878 ± 1.941
6.878SerThr: 6.878 ± 2.013
2.866SerVal: 2.866 ± 0.683
1.337SerTrp: 1.337 ± 0.609
2.102SerTyr: 2.102 ± 0.479
0.0SerXaa: 0.0 ± 0.0
Thr
5.732ThrAla: 5.732 ± 1.499
1.72ThrCys: 1.72 ± 0.516
2.866ThrAsp: 2.866 ± 0.872
3.057ThrGlu: 3.057 ± 0.289
3.057ThrPhe: 3.057 ± 1.073
3.248ThrGly: 3.248 ± 0.835
1.72ThrHis: 1.72 ± 0.483
5.541ThrIle: 5.541 ± 0.708
1.72ThrLys: 1.72 ± 0.575
7.451ThrLeu: 7.451 ± 0.699
1.528ThrMet: 1.528 ± 0.626
1.911ThrAsn: 1.911 ± 0.637
4.585ThrPro: 4.585 ± 2.15
3.439ThrGln: 3.439 ± 1.335
3.63ThrArg: 3.63 ± 0.935
4.203ThrSer: 4.203 ± 1.282
6.305ThrThr: 6.305 ± 2.329
3.63ThrVal: 3.63 ± 0.56
0.955ThrTrp: 0.955 ± 0.224
3.439ThrTyr: 3.439 ± 1.183
0.0ThrXaa: 0.0 ± 0.0
Val
4.968ValAla: 4.968 ± 0.57
0.764ValCys: 0.764 ± 0.331
2.484ValAsp: 2.484 ± 0.74
3.821ValGlu: 3.821 ± 1.042
2.293ValPhe: 2.293 ± 0.87
2.484ValGly: 2.484 ± 0.635
1.337ValHis: 1.337 ± 0.573
3.63ValIle: 3.63 ± 0.944
1.72ValLys: 1.72 ± 0.615
7.069ValLeu: 7.069 ± 1.061
2.293ValMet: 2.293 ± 0.669
2.293ValAsn: 2.293 ± 0.938
4.203ValPro: 4.203 ± 1.512
2.102ValGln: 2.102 ± 0.602
3.821ValArg: 3.821 ± 0.933
2.484ValSer: 2.484 ± 0.573
4.585ValThr: 4.585 ± 0.719
3.63ValVal: 3.63 ± 0.915
0.573ValTrp: 0.573 ± 0.278
1.72ValTyr: 1.72 ± 0.51
0.0ValXaa: 0.0 ± 0.0
Trp
1.337TrpAla: 1.337 ± 0.528
0.382TrpCys: 0.382 ± 0.344
0.191TrpAsp: 0.191 ± 0.129
0.191TrpGlu: 0.191 ± 0.129
0.191TrpPhe: 0.191 ± 0.129
0.764TrpGly: 0.764 ± 0.313
0.191TrpHis: 0.191 ± 0.129
0.764TrpIle: 0.764 ± 0.237
0.764TrpLys: 0.764 ± 0.442
0.382TrpLeu: 0.382 ± 0.257
0.382TrpMet: 0.382 ± 0.257
0.764TrpAsn: 0.764 ± 0.281
1.146TrpPro: 1.146 ± 0.538
0.191TrpGln: 0.191 ± 0.209
0.955TrpArg: 0.955 ± 0.527
0.955TrpSer: 0.955 ± 0.475
0.955TrpThr: 0.955 ± 0.306
0.955TrpVal: 0.955 ± 0.293
0.382TrpTrp: 0.382 ± 0.389
0.191TrpTyr: 0.191 ± 0.129
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.484TyrAla: 2.484 ± 0.616
0.955TyrCys: 0.955 ± 0.537
1.146TyrAsp: 1.146 ± 0.443
1.528TyrGlu: 1.528 ± 0.475
1.337TyrPhe: 1.337 ± 0.397
1.337TyrGly: 1.337 ± 0.618
0.191TyrHis: 0.191 ± 0.129
1.337TyrIle: 1.337 ± 0.514
0.764TyrLys: 0.764 ± 0.281
4.776TyrLeu: 4.776 ± 1.437
0.955TyrMet: 0.955 ± 0.434
1.337TyrAsn: 1.337 ± 0.395
1.911TyrPro: 1.911 ± 0.414
2.102TyrGln: 2.102 ± 0.615
1.146TyrArg: 1.146 ± 0.534
1.911TyrSer: 1.911 ± 0.782
0.955TyrThr: 0.955 ± 0.762
2.484TyrVal: 2.484 ± 0.542
0.573TyrTrp: 0.573 ± 0.34
2.484TyrTyr: 2.484 ± 0.787
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (5235 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski