Human papillomavirus 205

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 1

Average proteome isoelectric point is 6.13

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A166FKC2|A0A166FKC2_9PAPI Major capsid protein L1 OS=Human papillomavirus 205 OX=2259334 GN=L1 PE=3 SV=1
MM1 pKa = 6.91NTVKK5 pKa = 10.27SRR7 pKa = 11.84RR8 pKa = 11.84KK9 pKa = 9.37RR10 pKa = 11.84GSVVNLYY17 pKa = 9.91NKK19 pKa = 10.01CQLSGNCPEE28 pKa = 4.27DD29 pKa = 3.31VKK31 pKa = 11.6NKK33 pKa = 9.82IEE35 pKa = 4.45HH36 pKa = 5.69NTLADD41 pKa = 5.13RR42 pKa = 11.84LLKK45 pKa = 9.95WLGSFVYY52 pKa = 10.28FGGLGIGTSRR62 pKa = 11.84GTGGMTGYY70 pKa = 10.62NPLSTPSRR78 pKa = 11.84VTPQGTVIKK87 pKa = 8.45PTVVLDD93 pKa = 3.81PLGPPDD99 pKa = 4.44IVPIDD104 pKa = 3.66AVNPSSSSIVPLSEE118 pKa = 3.73VTPDD122 pKa = 3.48IEE124 pKa = 5.13LNTLGGVNVGGSDD137 pKa = 3.38LTTTEE142 pKa = 4.85LEE144 pKa = 4.66VITDD148 pKa = 4.45PDD150 pKa = 3.91PVSDD154 pKa = 3.84VTSTTSHH161 pKa = 6.23PTVITGGNDD170 pKa = 2.99DD171 pKa = 3.96VAVLDD176 pKa = 3.99VSPVEE181 pKa = 4.25PPPKK185 pKa = 9.98RR186 pKa = 11.84IALGTKK192 pKa = 9.26GNSSTPHH199 pKa = 6.52ISVTSSTTDD208 pKa = 2.55IGRR211 pKa = 11.84GADD214 pKa = 3.25FNVFVDD220 pKa = 3.86ATLGGDD226 pKa = 3.56SIGFAEE232 pKa = 5.7EE233 pKa = 4.11IPLDD237 pKa = 4.4EE238 pKa = 4.76INPRR242 pKa = 11.84LEE244 pKa = 4.12FEE246 pKa = 4.48IDD248 pKa = 3.21TAPRR252 pKa = 11.84TSTPRR257 pKa = 11.84EE258 pKa = 3.9VINRR262 pKa = 11.84TFGRR266 pKa = 11.84ARR268 pKa = 11.84NLYY271 pKa = 8.88NRR273 pKa = 11.84RR274 pKa = 11.84FRR276 pKa = 11.84QVATRR281 pKa = 11.84NLGFLGQPSRR291 pKa = 11.84AVTFEE296 pKa = 4.04FEE298 pKa = 4.22NPAYY302 pKa = 10.35APDD305 pKa = 3.44VSLSFEE311 pKa = 4.86RR312 pKa = 11.84DD313 pKa = 3.38LQDD316 pKa = 2.88IAAAPDD322 pKa = 3.39SDD324 pKa = 3.72FADD327 pKa = 3.79VVRR330 pKa = 11.84LGRR333 pKa = 11.84AQFSEE338 pKa = 4.39TDD340 pKa = 2.97SGTIRR345 pKa = 11.84LSRR348 pKa = 11.84AGKK351 pKa = 10.01RR352 pKa = 11.84GTIQTRR358 pKa = 11.84SGIRR362 pKa = 11.84IGEE365 pKa = 4.18DD366 pKa = 2.84VHH368 pKa = 7.92FYY370 pKa = 11.44YY371 pKa = 10.65DD372 pKa = 2.97ISKK375 pKa = 10.18IDD377 pKa = 3.4TADD380 pKa = 4.11AIEE383 pKa = 4.12MSNLGQHH390 pKa = 6.35SGDD393 pKa = 3.61LTIVDD398 pKa = 4.7ALAEE402 pKa = 4.26SSFVDD407 pKa = 3.66PFEE410 pKa = 4.74YY411 pKa = 9.89PDD413 pKa = 4.2PLHH416 pKa = 8.35SEE418 pKa = 4.21EE419 pKa = 4.73QQLLDD424 pKa = 3.97QLTEE428 pKa = 4.29DD429 pKa = 4.93FSNSHH434 pKa = 6.41LVLTGTRR441 pKa = 11.84RR442 pKa = 11.84NTTFTFPTLPPGIGLRR458 pKa = 11.84IYY460 pKa = 10.94LDD462 pKa = 4.58DD463 pKa = 4.74LPADD467 pKa = 4.28LFVSYY472 pKa = 9.4PQTTLTPAEE481 pKa = 4.6GLPITPFTPSVPIEE495 pKa = 4.13PLPPTFVDD503 pKa = 5.59FDD505 pKa = 3.75NFDD508 pKa = 3.81YY509 pKa = 11.07DD510 pKa = 3.36IHH512 pKa = 6.79PGLLRR517 pKa = 11.84RR518 pKa = 11.84KK519 pKa = 9.02KK520 pKa = 10.22RR521 pKa = 11.84KK522 pKa = 8.77RR523 pKa = 11.84TDD525 pKa = 3.18LVV527 pKa = 3.31

Molecular weight: 57.31 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A166FKB2|A0A166FKB2_9PAPI Minor capsid protein L2 OS=Human papillomavirus 205 OX=2259334 GN=L2 PE=3 SV=1
MM1 pKa = 7.68EE2 pKa = 4.78SLINRR7 pKa = 11.84FDD9 pKa = 3.79AVQEE13 pKa = 4.71AILSHH18 pKa = 6.76IEE20 pKa = 4.09SGSTTLEE27 pKa = 3.8SQIEE31 pKa = 4.06YY32 pKa = 9.38WEE34 pKa = 4.06NVRR37 pKa = 11.84KK38 pKa = 9.97EE39 pKa = 4.29NIIMHH44 pKa = 6.15YY45 pKa = 10.27ARR47 pKa = 11.84KK48 pKa = 9.63QGLTTLGMQPLPALAVTEE66 pKa = 4.36YY67 pKa = 10.4NAKK70 pKa = 10.05EE71 pKa = 4.03AIKK74 pKa = 10.71LSLTLQSLLKK84 pKa = 10.66SPFGTEE90 pKa = 3.25PWTLTEE96 pKa = 5.18VSAQLINTPPQNCLKK111 pKa = 10.46KK112 pKa = 10.02RR113 pKa = 11.84GYY115 pKa = 9.27EE116 pKa = 3.89VEE118 pKa = 3.93VWFDD122 pKa = 3.68NNKK125 pKa = 9.96DD126 pKa = 3.42NAMVYY131 pKa = 9.72PNWDD135 pKa = 3.53RR136 pKa = 11.84IYY138 pKa = 10.74YY139 pKa = 9.96QDD141 pKa = 3.98TNEE144 pKa = 3.55IWHH147 pKa = 5.91LVKK150 pKa = 11.2GEE152 pKa = 3.7VDD154 pKa = 3.06YY155 pKa = 11.42DD156 pKa = 3.3GCYY159 pKa = 10.03FVDD162 pKa = 3.58HH163 pKa = 6.77TGDD166 pKa = 3.08RR167 pKa = 11.84AYY169 pKa = 10.0FTIFNADD176 pKa = 3.18AEE178 pKa = 4.65RR179 pKa = 11.84FSEE182 pKa = 4.14TGKK185 pKa = 7.95WTVHH189 pKa = 5.79YY190 pKa = 7.41KK191 pKa = 8.25TQVISSSIVSSTSSHH206 pKa = 6.01YY207 pKa = 11.13SSIDD211 pKa = 3.25EE212 pKa = 4.7DD213 pKa = 5.13PIPGPSTYY221 pKa = 10.3TSPTKK226 pKa = 10.38KK227 pKa = 10.21SSAGHH232 pKa = 6.21KK233 pKa = 8.95EE234 pKa = 4.5SPGHH238 pKa = 6.21PSSTTSPEE246 pKa = 3.83TKK248 pKa = 9.8NIRR251 pKa = 11.84FRR253 pKa = 11.84RR254 pKa = 11.84GRR256 pKa = 11.84QQGEE260 pKa = 4.12SGASGGEE267 pKa = 4.08TPFKK271 pKa = 10.18RR272 pKa = 11.84RR273 pKa = 11.84RR274 pKa = 11.84RR275 pKa = 11.84GGLGSAPSAAEE286 pKa = 3.46VGQRR290 pKa = 11.84HH291 pKa = 5.46RR292 pKa = 11.84TPQRR296 pKa = 11.84KK297 pKa = 8.71GLSRR301 pKa = 11.84LGLLQEE307 pKa = 4.43EE308 pKa = 4.73ARR310 pKa = 11.84DD311 pKa = 3.72PPLICISGTANSLKK325 pKa = 9.47CWRR328 pKa = 11.84YY329 pKa = 9.58RR330 pKa = 11.84KK331 pKa = 9.93SNQYY335 pKa = 7.88PQRR338 pKa = 11.84FLVMSTVFQWVGDD351 pKa = 3.75TSPAHH356 pKa = 6.15SRR358 pKa = 11.84LLVAFINNAQRR369 pKa = 11.84EE370 pKa = 4.63AFVKK374 pKa = 9.08HH375 pKa = 4.93TQLPRR380 pKa = 11.84NATYY384 pKa = 10.42TFGNLNKK391 pKa = 10.42LL392 pKa = 3.63

Molecular weight: 44.28 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2274

97

603

379.0

42.59

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.761 ± 0.494

2.507 ± 0.731

6.069 ± 0.787

5.717 ± 0.352

5.057 ± 0.406

5.893 ± 0.729

1.979 ± 0.207

5.145 ± 0.288

5.145 ± 0.793

8.663 ± 0.524

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.495 ± 0.322

5.893 ± 0.531

5.849 ± 0.87

4.134 ± 0.567

5.145 ± 0.664

7.828 ± 0.468

6.904 ± 0.855

6.069 ± 0.487

1.187 ± 0.339

3.562 ± 0.499
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski