Amino acid dipepetide frequency for Ophiocordyceps camponoti-leonardi (nom. inval.)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.907AlaAla: 11.907 ± 0.094	1.215AlaCys: 1.215 ± 0.021	5.247AlaAsp: 5.247 ± 0.035	5.652AlaGlu: 5.652 ± 0.048	3.074AlaPhe: 3.074 ± 0.034	6.381AlaGly: 6.381 ± 0.049	1.841AlaHis: 1.841 ± 0.022	3.784AlaIle: 3.784 ± 0.034	4.102AlaLys: 4.102 ± 0.045	8.12AlaLeu: 8.12 ± 0.055	2.189AlaMet: 2.189 ± 0.024	2.756AlaAsn: 2.756 ± 0.033	4.955AlaPro: 4.955 ± 0.052	3.382AlaGln: 3.382 ± 0.034	6.025AlaArg: 6.025 ± 0.036	8.269AlaSer: 8.269 ± 0.062	5.364AlaThr: 5.364 ± 0.041	6.483AlaVal: 6.483 ± 0.055	1.186AlaTrp: 1.186 ± 0.02	2.061AlaTyr: 2.061 ± 0.033	0.0AlaXaa: 0.0 ± 0.0
Cys	1.019CysAla: 1.019 ± 0.018	0.265CysCys: 0.265 ± 0.01	0.729CysAsp: 0.729 ± 0.015	0.639CysGlu: 0.639 ± 0.014	0.559CysPhe: 0.559 ± 0.013	1.006CysGly: 1.006 ± 0.018	0.39CysHis: 0.39 ± 0.011	0.608CysIle: 0.608 ± 0.012	0.486CysLys: 0.486 ± 0.013	1.36CysLeu: 1.36 ± 0.02	0.252CysMet: 0.252 ± 0.007	0.404CysAsn: 0.404 ± 0.01	0.748CysPro: 0.748 ± 0.018	0.464CysGln: 0.464 ± 0.012	0.959CysArg: 0.959 ± 0.018	0.963CysSer: 0.963 ± 0.018	0.59CysThr: 0.59 ± 0.014	0.881CysVal: 0.881 ± 0.019	0.197CysTrp: 0.197 ± 0.008	0.338CysTyr: 0.338 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	5.768AspAla: 5.768 ± 0.047	0.714AspCys: 0.714 ± 0.016	6.545AspAsp: 6.545 ± 0.09	5.251AspGlu: 5.251 ± 0.045	2.239AspPhe: 2.239 ± 0.023	5.131AspGly: 5.131 ± 0.045	1.258AspHis: 1.258 ± 0.018	2.448AspIle: 2.448 ± 0.029	2.57AspLys: 2.57 ± 0.031	5.048AspLeu: 5.048 ± 0.041	1.438AspMet: 1.438 ± 0.02	1.762AspAsn: 1.762 ± 0.022	3.1AspPro: 3.1 ± 0.031	1.886AspGln: 1.886 ± 0.026	3.591AspArg: 3.591 ± 0.037	4.172AspSer: 4.172 ± 0.048	2.498AspThr: 2.498 ± 0.026	4.381AspVal: 4.381 ± 0.039	0.892AspTrp: 0.892 ± 0.016	1.503AspTyr: 1.503 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	6.488GluAla: 6.488 ± 0.053	0.617GluCys: 0.617 ± 0.015	4.141GluAsp: 4.141 ± 0.039	5.444GluGlu: 5.444 ± 0.057	1.705GluPhe: 1.705 ± 0.022	3.651GluGly: 3.651 ± 0.037	1.199GluHis: 1.199 ± 0.022	2.27GluIle: 2.27 ± 0.027	3.36GluLys: 3.36 ± 0.041	5.114GluLeu: 5.114 ± 0.044	1.542GluMet: 1.542 ± 0.019	1.799GluAsn: 1.799 ± 0.024	2.997GluPro: 2.997 ± 0.038	2.353GluGln: 2.353 ± 0.034	4.177GluArg: 4.177 ± 0.04	4.103GluSer: 4.103 ± 0.038	3.369GluThr: 3.369 ± 0.031	3.405GluVal: 3.405 ± 0.03	0.792GluTrp: 0.792 ± 0.014	1.373GluTyr: 1.373 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	3.018PheAla: 3.018 ± 0.03	0.567PheCys: 0.567 ± 0.012	2.26PheAsp: 2.26 ± 0.024	1.931PheGlu: 1.931 ± 0.025	1.527PhePhe: 1.527 ± 0.023	2.636PheGly: 2.636 ± 0.033	0.884PheHis: 0.884 ± 0.016	1.475PheIle: 1.475 ± 0.02	1.294PheLys: 1.294 ± 0.019	3.292PheLeu: 3.292 ± 0.037	0.701PheMet: 0.701 ± 0.013	1.222PheAsn: 1.222 ± 0.018	1.802PhePro: 1.802 ± 0.019	1.199PheGln: 1.199 ± 0.019	2.184PheArg: 2.184 ± 0.024	2.769PheSer: 2.769 ± 0.032	1.774PheThr: 1.774 ± 0.023	2.463PheVal: 2.463 ± 0.032	0.559PheTrp: 0.559 ± 0.014	0.968PheTyr: 0.968 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.465GlyAla: 5.465 ± 0.046	0.938GlyCys: 0.938 ± 0.019	4.103GlyAsp: 4.103 ± 0.039	3.796GlyGlu: 3.796 ± 0.033	2.689GlyPhe: 2.689 ± 0.033	7.459GlyGly: 7.459 ± 0.109	1.784GlyHis: 1.784 ± 0.023	3.035GlyIle: 3.035 ± 0.034	3.276GlyLys: 3.276 ± 0.037	6.18GlyLeu: 6.18 ± 0.051	1.499GlyMet: 1.499 ± 0.023	2.406GlyAsn: 2.406 ± 0.063	3.732GlyPro: 3.732 ± 0.124	2.64GlyGln: 2.64 ± 0.029	5.134GlyArg: 5.134 ± 0.048	6.15GlySer: 6.15 ± 0.085	3.54GlyThr: 3.54 ± 0.04	4.311GlyVal: 4.311 ± 0.041	1.13GlyTrp: 1.13 ± 0.019	1.913GlyTyr: 1.913 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	1.898HisAla: 1.898 ± 0.021	0.347HisCys: 0.347 ± 0.01	1.501HisAsp: 1.501 ± 0.021	1.256HisGlu: 1.256 ± 0.023	0.835HisPhe: 0.835 ± 0.013	1.795HisGly: 1.795 ± 0.025	1.308HisHis: 1.308 ± 0.035	0.952HisIle: 0.952 ± 0.016	0.84HisLys: 0.84 ± 0.017	2.305HisLeu: 2.305 ± 0.026	0.498HisMet: 0.498 ± 0.012	0.722HisAsn: 0.722 ± 0.017	1.647HisPro: 1.647 ± 0.024	1.147HisGln: 1.147 ± 0.026	1.773HisArg: 1.773 ± 0.024	1.622HisSer: 1.622 ± 0.023	0.99HisThr: 0.99 ± 0.015	1.621HisVal: 1.621 ± 0.022	0.31HisTrp: 0.31 ± 0.009	0.637HisTyr: 0.637 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	3.392IleAla: 3.392 ± 0.037	0.659IleCys: 0.659 ± 0.013	2.567IleAsp: 2.567 ± 0.029	2.273IleGlu: 2.273 ± 0.028	1.658IlePhe: 1.658 ± 0.023	2.648IleGly: 2.648 ± 0.033	1.001IleHis: 1.001 ± 0.014	1.92IleIle: 1.92 ± 0.027	1.891IleLys: 1.891 ± 0.025	3.716IleLeu: 3.716 ± 0.037	0.901IleMet: 0.901 ± 0.015	1.476IleAsn: 1.476 ± 0.023	2.371IlePro: 2.371 ± 0.027	1.454IleGln: 1.454 ± 0.021	2.752IleArg: 2.752 ± 0.027	3.044IleSer: 3.044 ± 0.029	2.048IleThr: 2.048 ± 0.024	2.865IleVal: 2.865 ± 0.032	0.571IleTrp: 0.571 ± 0.014	1.071IleTyr: 1.071 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.408LysAla: 4.408 ± 0.045	0.48LysCys: 0.48 ± 0.014	2.57LysAsp: 2.57 ± 0.029	2.864LysGlu: 2.864 ± 0.03	1.222LysPhe: 1.222 ± 0.021	2.745LysGly: 2.745 ± 0.031	0.967LysHis: 0.967 ± 0.018	1.721LysIle: 1.721 ± 0.023	3.215LysLys: 3.215 ± 0.05	3.874LysLeu: 3.874 ± 0.038	1.072LysMet: 1.072 ± 0.017	1.405LysAsn: 1.405 ± 0.022	2.751LysPro: 2.751 ± 0.034	1.777LysGln: 1.777 ± 0.025	3.464LysArg: 3.464 ± 0.035	3.193LysSer: 3.193 ± 0.032	2.846LysThr: 2.846 ± 0.03	2.548LysVal: 2.548 ± 0.029	0.551LysTrp: 0.551 ± 0.012	1.061LysTyr: 1.061 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	8.639LeuAla: 8.639 ± 0.065	1.265LeuCys: 1.265 ± 0.019	5.527LeuAsp: 5.527 ± 0.04	5.176LeuGlu: 5.176 ± 0.05	3.188LeuPhe: 3.188 ± 0.036	5.977LeuGly: 5.977 ± 0.048	2.199LeuHis: 2.199 ± 0.026	3.407LeuIle: 3.407 ± 0.037	3.644LeuLys: 3.644 ± 0.037	8.856LeuLeu: 8.856 ± 0.078	1.844LeuMet: 1.844 ± 0.025	2.661LeuAsn: 2.661 ± 0.031	5.564LeuPro: 5.564 ± 0.048	3.59LeuGln: 3.59 ± 0.035	6.707LeuArg: 6.707 ± 0.049	7.448LeuSer: 7.448 ± 0.046	4.682LeuThr: 4.682 ± 0.032	6.025LeuVal: 6.025 ± 0.048	1.187LeuTrp: 1.187 ± 0.02	2.181LeuTyr: 2.181 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.562MetAla: 2.562 ± 0.026	0.232MetCys: 0.232 ± 0.007	1.287MetAsp: 1.287 ± 0.017	1.299MetGlu: 1.299 ± 0.019	0.655MetPhe: 0.655 ± 0.015	1.452MetGly: 1.452 ± 0.021	0.449MetHis: 0.449 ± 0.01	0.823MetIle: 0.823 ± 0.015	0.948MetLys: 0.948 ± 0.016	1.992MetLeu: 1.992 ± 0.025	0.667MetMet: 0.667 ± 0.014	0.688MetAsn: 0.688 ± 0.013	1.396MetPro: 1.396 ± 0.02	0.831MetGln: 0.831 ± 0.017	1.489MetArg: 1.489 ± 0.019	1.817MetSer: 1.817 ± 0.021	1.522MetThr: 1.522 ± 0.018	1.345MetVal: 1.345 ± 0.021	0.252MetTrp: 0.252 ± 0.008	0.459MetTyr: 0.459 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.712AsnAla: 2.712 ± 0.028	0.395AsnCys: 0.395 ± 0.009	1.829AsnAsp: 1.829 ± 0.024	1.668AsnGlu: 1.668 ± 0.024	1.156AsnPhe: 1.156 ± 0.021	2.653AsnGly: 2.653 ± 0.063	0.783AsnHis: 0.783 ± 0.015	1.454AsnIle: 1.454 ± 0.02	1.478AsnLys: 1.478 ± 0.021	2.803AsnLeu: 2.803 ± 0.029	0.769AsnMet: 0.769 ± 0.016	1.436AsnAsn: 1.436 ± 0.039	1.977AsnPro: 1.977 ± 0.025	1.132AsnGln: 1.132 ± 0.02	1.942AsnArg: 1.942 ± 0.025	2.297AsnSer: 2.297 ± 0.03	1.541AsnThr: 1.541 ± 0.021	2.099AsnVal: 2.099 ± 0.026	0.46AsnTrp: 0.46 ± 0.011	0.853AsnTyr: 0.853 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.677ProAla: 5.677 ± 0.065	0.629ProCys: 0.629 ± 0.013	3.59ProAsp: 3.59 ± 0.067	3.447ProGlu: 3.447 ± 0.038	1.925ProPhe: 1.925 ± 0.024	4.073ProGly: 4.073 ± 0.075	1.35ProHis: 1.35 ± 0.02	2.064ProIle: 2.064 ± 0.024	2.33ProLys: 2.33 ± 0.032	4.998ProLeu: 4.998 ± 0.036	1.123ProMet: 1.123 ± 0.018	1.727ProAsn: 1.727 ± 0.024	6.526ProPro: 6.526 ± 0.097	2.459ProGln: 2.459 ± 0.038	4.023ProArg: 4.023 ± 0.04	6.386ProSer: 6.386 ± 0.06	3.712ProThr: 3.712 ± 0.045	3.791ProVal: 3.791 ± 0.035	0.751ProTrp: 0.751 ± 0.016	1.383ProTyr: 1.383 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.585GlnAla: 3.585 ± 0.037	0.403GlnCys: 0.403 ± 0.011	2.05GlnAsp: 2.05 ± 0.024	2.132GlnGlu: 2.132 ± 0.029	1.104GlnPhe: 1.104 ± 0.019	2.475GlnGly: 2.475 ± 0.03	1.181GlnHis: 1.181 ± 0.023	1.451GlnIle: 1.451 ± 0.021	1.706GlnLys: 1.706 ± 0.023	3.559GlnLeu: 3.559 ± 0.038	0.902GlnMet: 0.902 ± 0.018	1.174GlnAsn: 1.174 ± 0.022	2.761GlnPro: 2.761 ± 0.042	3.703GlnGln: 3.703 ± 0.107	2.961GlnArg: 2.961 ± 0.032	2.841GlnSer: 2.841 ± 0.037	2.129GlnThr: 2.129 ± 0.025	2.194GlnVal: 2.194 ± 0.026	0.494GlnTrp: 0.494 ± 0.013	0.938GlnTyr: 0.938 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.636ArgAla: 5.636 ± 0.044	0.934ArgCys: 0.934 ± 0.018	4.138ArgAsp: 4.138 ± 0.04	4.162ArgGlu: 4.162 ± 0.039	2.396ArgPhe: 2.396 ± 0.027	4.481ArgGly: 4.481 ± 0.046	1.98ArgHis: 1.98 ± 0.025	2.86ArgIle: 2.86 ± 0.032	3.441ArgLys: 3.441 ± 0.038	6.823ArgLeu: 6.823 ± 0.046	1.432ArgMet: 1.432 ± 0.018	2.228ArgAsn: 2.228 ± 0.025	4.356ArgPro: 4.356 ± 0.044	3.124ArgGln: 3.124 ± 0.032	7.152ArgArg: 7.152 ± 0.063	5.389ArgSer: 5.389 ± 0.047	3.382ArgThr: 3.382 ± 0.034	3.831ArgVal: 3.831 ± 0.036	1.042ArgTrp: 1.042 ± 0.017	1.706ArgTyr: 1.706 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	7.128SerAla: 7.128 ± 0.06	0.982SerCys: 0.982 ± 0.016	4.45SerAsp: 4.45 ± 0.041	3.873SerGlu: 3.873 ± 0.038	2.895SerPhe: 2.895 ± 0.027	5.658SerGly: 5.658 ± 0.065	1.931SerHis: 1.931 ± 0.024	3.275SerIle: 3.275 ± 0.035	3.351SerLys: 3.351 ± 0.031	7.508SerLeu: 7.508 ± 0.047	1.709SerMet: 1.709 ± 0.021	2.492SerAsn: 2.492 ± 0.031	5.861SerPro: 5.861 ± 0.07	3.11SerGln: 3.11 ± 0.037	5.903SerArg: 5.903 ± 0.046	10.578SerSer: 10.578 ± 0.141	4.998SerThr: 4.998 ± 0.051	4.771SerVal: 4.771 ± 0.036	1.106SerTrp: 1.106 ± 0.017	1.868SerTyr: 1.868 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	5.497ThrAla: 5.497 ± 0.042	0.711ThrCys: 0.711 ± 0.015	2.804ThrAsp: 2.804 ± 0.029	2.803ThrGlu: 2.803 ± 0.032	1.834ThrPhe: 1.834 ± 0.023	3.882ThrGly: 3.882 ± 0.041	1.08ThrHis: 1.08 ± 0.017	2.423ThrIle: 2.423 ± 0.026	2.305ThrLys: 2.305 ± 0.029	4.802ThrLeu: 4.802 ± 0.04	1.304ThrMet: 1.304 ± 0.018	1.613ThrAsn: 1.613 ± 0.019	3.858ThrPro: 3.858 ± 0.039	1.777ThrGln: 1.777 ± 0.023	3.282ThrArg: 3.282 ± 0.032	4.919ThrSer: 4.919 ± 0.05	4.635ThrThr: 4.635 ± 0.072	3.661ThrVal: 3.661 ± 0.034	0.746ThrTrp: 0.746 ± 0.014	1.292ThrTyr: 1.292 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	6.092ValAla: 6.092 ± 0.046	0.915ValCys: 0.915 ± 0.017	4.37ValAsp: 4.37 ± 0.036	4.104ValGlu: 4.104 ± 0.034	2.41ValPhe: 2.41 ± 0.029	4.232ValGly: 4.232 ± 0.042	1.343ValHis: 1.343 ± 0.02	2.67ValIle: 2.67 ± 0.027	2.894ValLys: 2.894 ± 0.029	5.687ValLeu: 5.687 ± 0.055	1.427ValMet: 1.427 ± 0.019	2.074ValAsn: 2.074 ± 0.026	3.635ValPro: 3.635 ± 0.029	2.264ValGln: 2.264 ± 0.022	4.165ValArg: 4.165 ± 0.035	4.775ValSer: 4.775 ± 0.043	3.534ValThr: 3.534 ± 0.035	5.048ValVal: 5.048 ± 0.052	0.85ValTrp: 0.85 ± 0.016	1.599ValTyr: 1.599 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	1.115TrpAla: 1.115 ± 0.019	0.197TrpCys: 0.197 ± 0.007	0.864TrpAsp: 0.864 ± 0.018	0.766TrpGlu: 0.766 ± 0.014	0.494TrpPhe: 0.494 ± 0.012	0.793TrpGly: 0.793 ± 0.015	0.379TrpHis: 0.379 ± 0.01	0.648TrpIle: 0.648 ± 0.014	0.667TrpLys: 0.667 ± 0.013	1.374TrpLeu: 1.374 ± 0.021	0.341TrpMet: 0.341 ± 0.009	0.553TrpAsn: 0.553 ± 0.013	0.631TrpPro: 0.631 ± 0.013	0.546TrpGln: 0.546 ± 0.012	1.097TrpArg: 1.097 ± 0.018	1.009TrpSer: 1.009 ± 0.017	0.891TrpThr: 0.891 ± 0.016	0.748TrpVal: 0.748 ± 0.015	0.27TrpTrp: 0.27 ± 0.008	0.35TrpTyr: 0.35 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.985TyrAla: 1.985 ± 0.025	0.392TyrCys: 0.392 ± 0.011	1.621TyrAsp: 1.621 ± 0.02	1.363TyrGlu: 1.363 ± 0.025	0.961TyrPhe: 0.961 ± 0.016	2.05TyrGly: 2.05 ± 0.064	0.699TyrHis: 0.699 ± 0.014	0.989TyrIle: 0.989 ± 0.016	0.933TyrLys: 0.933 ± 0.017	2.355TyrLeu: 2.355 ± 0.026	0.555TyrMet: 0.555 ± 0.013	0.839TyrAsn: 0.839 ± 0.017	1.296TyrPro: 1.296 ± 0.021	0.907TyrGln: 0.907 ± 0.017	1.714TyrArg: 1.714 ± 0.024	1.704TyrSer: 1.704 ± 0.023	1.183TyrThr: 1.183 ± 0.021	1.621TyrVal: 1.621 ± 0.023	0.385TyrTrp: 0.385 ± 0.011	0.732TyrTyr: 0.732 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7043 proteins (3884336 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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