Amino acid dipepetide frequency for Simian adenovirus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.041AlaAla: 10.041 ± 1.678
1.461AlaCys: 1.461 ± 0.467
3.377AlaAsp: 3.377 ± 0.556
3.925AlaGlu: 3.925 ± 0.723
3.195AlaPhe: 3.195 ± 0.539
4.108AlaGly: 4.108 ± 0.761
1.369AlaHis: 1.369 ± 0.351
4.016AlaIle: 4.016 ± 0.546
2.008AlaLys: 2.008 ± 0.365
9.311AlaLeu: 9.311 ± 1.196
1.461AlaMet: 1.461 ± 0.333
3.377AlaAsn: 3.377 ± 1.105
5.477AlaPro: 5.477 ± 0.872
2.83AlaGln: 2.83 ± 0.373
5.66AlaArg: 5.66 ± 0.989
4.838AlaSer: 4.838 ± 0.799
4.747AlaThr: 4.747 ± 0.518
6.207AlaVal: 6.207 ± 0.894
0.639AlaTrp: 0.639 ± 0.224
2.373AlaTyr: 2.373 ± 0.409
0.0AlaXaa: 0.0 ± 0.0
Cys
1.552CysAla: 1.552 ± 0.439
0.639CysCys: 0.639 ± 0.321
1.004CysAsp: 1.004 ± 0.243
1.004CysGlu: 1.004 ± 0.338
1.004CysPhe: 1.004 ± 0.318
1.369CysGly: 1.369 ± 0.46
0.548CysHis: 0.548 ± 0.194
0.73CysIle: 0.73 ± 0.352
0.456CysLys: 0.456 ± 0.193
1.734CysLeu: 1.734 ± 0.401
0.456CysMet: 0.456 ± 0.216
0.913CysAsn: 0.913 ± 0.35
1.369CysPro: 1.369 ± 0.296
0.548CysGln: 0.548 ± 0.246
1.004CysArg: 1.004 ± 0.346
1.917CysSer: 1.917 ± 0.427
1.095CysThr: 1.095 ± 0.296
1.278CysVal: 1.278 ± 0.398
0.365CysTrp: 0.365 ± 0.198
0.73CysTyr: 0.73 ± 0.254
0.0CysXaa: 0.0 ± 0.0
Asp
2.921AspAla: 2.921 ± 0.547
1.187AspCys: 1.187 ± 0.384
2.008AspAsp: 2.008 ± 0.56
3.651AspGlu: 3.651 ± 0.66
2.008AspPhe: 2.008 ± 0.362
2.738AspGly: 2.738 ± 0.606
1.369AspHis: 1.369 ± 0.516
1.734AspIle: 1.734 ± 0.359
1.187AspLys: 1.187 ± 0.238
5.203AspLeu: 5.203 ± 1.001
1.552AspMet: 1.552 ± 0.467
2.008AspAsn: 2.008 ± 0.441
3.56AspPro: 3.56 ± 0.54
0.913AspGln: 0.913 ± 0.232
3.651AspArg: 3.651 ± 0.689
2.921AspSer: 2.921 ± 0.551
2.099AspThr: 2.099 ± 0.452
4.108AspVal: 4.108 ± 0.509
1.095AspTrp: 1.095 ± 0.312
1.917AspTyr: 1.917 ± 0.386
0.0AspXaa: 0.0 ± 0.0
Glu
5.294GluAla: 5.294 ± 1.037
0.73GluCys: 0.73 ± 0.268
3.834GluAsp: 3.834 ± 0.804
7.029GluGlu: 7.029 ± 1.368
1.826GluPhe: 1.826 ± 0.351
3.104GluGly: 3.104 ± 0.494
1.369GluHis: 1.369 ± 0.344
2.556GluIle: 2.556 ± 0.443
2.556GluLys: 2.556 ± 0.695
5.386GluLeu: 5.386 ± 0.788
1.278GluMet: 1.278 ± 0.412
3.012GluAsn: 3.012 ± 0.829
3.104GluPro: 3.104 ± 0.541
2.282GluGln: 2.282 ± 0.522
3.743GluArg: 3.743 ± 0.692
2.191GluSer: 2.191 ± 0.604
4.108GluThr: 4.108 ± 0.567
4.016GluVal: 4.016 ± 0.836
0.73GluTrp: 0.73 ± 0.263
1.552GluTyr: 1.552 ± 0.351
0.0GluXaa: 0.0 ± 0.0
Phe
2.556PheAla: 2.556 ± 0.374
0.548PheCys: 0.548 ± 0.216
2.465PheAsp: 2.465 ± 0.419
1.369PheGlu: 1.369 ± 0.489
2.008PhePhe: 2.008 ± 0.421
1.369PheGly: 1.369 ± 0.425
1.369PheHis: 1.369 ± 0.455
0.913PheIle: 0.913 ± 0.287
1.187PheLys: 1.187 ± 0.382
4.199PheLeu: 4.199 ± 0.567
1.461PheMet: 1.461 ± 0.353
2.099PheAsn: 2.099 ± 0.528
2.008PhePro: 2.008 ± 0.341
1.917PheGln: 1.917 ± 0.362
3.469PheArg: 3.469 ± 0.579
3.469PheSer: 3.469 ± 0.528
2.83PheThr: 2.83 ± 0.671
3.743PheVal: 3.743 ± 0.5
0.365PheTrp: 0.365 ± 0.203
1.826PheTyr: 1.826 ± 0.415
0.0PheXaa: 0.0 ± 0.0
Gly
4.108GlyAla: 4.108 ± 0.631
0.913GlyCys: 0.913 ± 0.237
3.195GlyAsp: 3.195 ± 0.528
3.195GlyGlu: 3.195 ± 0.567
2.282GlyPhe: 2.282 ± 0.489
4.747GlyGly: 4.747 ± 1.37
1.643GlyHis: 1.643 ± 0.486
3.286GlyIle: 3.286 ± 0.484
1.461GlyLys: 1.461 ± 0.477
5.477GlyLeu: 5.477 ± 1.082
1.095GlyMet: 1.095 ± 0.277
2.647GlyAsn: 2.647 ± 0.824
3.195GlyPro: 3.195 ± 0.629
2.647GlyGln: 2.647 ± 0.588
5.203GlyArg: 5.203 ± 0.636
4.29GlySer: 4.29 ± 0.601
2.373GlyThr: 2.373 ± 0.414
4.838GlyVal: 4.838 ± 0.782
0.913GlyTrp: 0.913 ± 0.251
1.917GlyTyr: 1.917 ± 0.535
0.0GlyXaa: 0.0 ± 0.0
His
1.734HisAla: 1.734 ± 0.397
0.822HisCys: 0.822 ± 0.276
1.187HisAsp: 1.187 ± 0.338
1.004HisGlu: 1.004 ± 0.32
0.913HisPhe: 0.913 ± 0.269
1.917HisGly: 1.917 ± 0.313
0.639HisHis: 0.639 ± 0.276
0.73HisIle: 0.73 ± 0.283
0.73HisLys: 0.73 ± 0.275
3.195HisLeu: 3.195 ± 0.742
0.365HisMet: 0.365 ± 0.194
1.004HisAsn: 1.004 ± 0.383
1.552HisPro: 1.552 ± 0.489
0.639HisGln: 0.639 ± 0.166
2.373HisArg: 2.373 ± 0.409
1.643HisSer: 1.643 ± 0.388
0.822HisThr: 0.822 ± 0.257
1.552HisVal: 1.552 ± 0.424
0.183HisTrp: 0.183 ± 0.139
0.913HisTyr: 0.913 ± 0.249
0.0HisXaa: 0.0 ± 0.0
Ile
3.195IleAla: 3.195 ± 0.493
0.822IleCys: 0.822 ± 0.308
2.191IleAsp: 2.191 ± 0.408
1.734IleGlu: 1.734 ± 0.31
1.917IlePhe: 1.917 ± 0.456
2.099IleGly: 2.099 ± 0.639
1.187IleHis: 1.187 ± 0.443
1.917IleIle: 1.917 ± 0.498
2.465IleLys: 2.465 ± 0.603
3.651IleLeu: 3.651 ± 0.515
0.913IleMet: 0.913 ± 0.254
2.099IleAsn: 2.099 ± 0.417
3.012IlePro: 3.012 ± 0.509
1.643IleGln: 1.643 ± 0.475
2.282IleArg: 2.282 ± 0.582
3.743IleSer: 3.743 ± 0.825
2.008IleThr: 2.008 ± 0.411
2.373IleVal: 2.373 ± 0.377
0.456IleTrp: 0.456 ± 0.193
1.095IleTyr: 1.095 ± 0.436
0.0IleXaa: 0.0 ± 0.0
Lys
2.191LysAla: 2.191 ± 0.504
0.456LysCys: 0.456 ± 0.265
1.278LysAsp: 1.278 ± 0.393
2.373LysGlu: 2.373 ± 0.434
1.826LysPhe: 1.826 ± 0.383
2.647LysGly: 2.647 ± 0.401
0.913LysHis: 0.913 ± 0.346
2.465LysIle: 2.465 ± 0.672
0.913LysLys: 0.913 ± 0.291
2.465LysLeu: 2.465 ± 0.523
0.639LysMet: 0.639 ± 0.286
1.734LysAsn: 1.734 ± 0.332
2.373LysPro: 2.373 ± 0.359
1.004LysGln: 1.004 ± 0.27
3.469LysArg: 3.469 ± 0.634
2.099LysSer: 2.099 ± 0.512
2.008LysThr: 2.008 ± 0.419
2.282LysVal: 2.282 ± 0.569
0.365LysTrp: 0.365 ± 0.24
0.822LysTyr: 0.822 ± 0.252
0.0LysXaa: 0.0 ± 0.0
Leu
7.576LeuAla: 7.576 ± 0.962
2.008LeuCys: 2.008 ± 0.557
3.925LeuAsp: 3.925 ± 0.57
5.66LeuGlu: 5.66 ± 1.115
2.647LeuPhe: 2.647 ± 0.68
5.568LeuGly: 5.568 ± 0.603
3.651LeuHis: 3.651 ± 0.56
2.921LeuIle: 2.921 ± 0.51
4.747LeuLys: 4.747 ± 1.024
9.767LeuLeu: 9.767 ± 1.095
2.465LeuMet: 2.465 ± 0.364
5.203LeuAsn: 5.203 ± 0.922
7.394LeuPro: 7.394 ± 0.812
5.386LeuGln: 5.386 ± 0.816
7.303LeuArg: 7.303 ± 0.941
6.937LeuSer: 6.937 ± 1.029
6.846LeuThr: 6.846 ± 1.023
5.112LeuVal: 5.112 ± 0.777
1.278LeuTrp: 1.278 ± 0.32
3.743LeuTyr: 3.743 ± 0.597
0.0LeuXaa: 0.0 ± 0.0
Met
2.373MetAla: 2.373 ± 0.406
0.274MetCys: 0.274 ± 0.186
0.822MetAsp: 0.822 ± 0.274
1.917MetGlu: 1.917 ± 0.462
0.639MetPhe: 0.639 ± 0.298
1.552MetGly: 1.552 ± 0.313
0.822MetHis: 0.822 ± 0.318
1.004MetIle: 1.004 ± 0.24
0.639MetLys: 0.639 ± 0.251
1.917MetLeu: 1.917 ± 0.68
0.456MetMet: 0.456 ± 0.186
1.004MetAsn: 1.004 ± 0.277
1.734MetPro: 1.734 ± 0.418
0.73MetGln: 0.73 ± 0.3
1.278MetArg: 1.278 ± 0.356
1.004MetSer: 1.004 ± 0.229
1.461MetThr: 1.461 ± 0.379
1.095MetVal: 1.095 ± 0.41
0.365MetTrp: 0.365 ± 0.192
0.822MetTyr: 0.822 ± 0.216
0.0MetXaa: 0.0 ± 0.0
Asn
3.286AsnAla: 3.286 ± 0.611
1.187AsnCys: 1.187 ± 0.311
2.008AsnAsp: 2.008 ± 0.463
2.099AsnGlu: 2.099 ± 0.393
3.286AsnPhe: 3.286 ± 0.441
2.282AsnGly: 2.282 ± 0.69
1.004AsnHis: 1.004 ± 0.374
1.917AsnIle: 1.917 ± 0.469
1.187AsnLys: 1.187 ± 0.323
3.925AsnLeu: 3.925 ± 0.558
1.187AsnMet: 1.187 ± 0.438
2.099AsnAsn: 2.099 ± 0.781
3.56AsnPro: 3.56 ± 0.637
1.826AsnGln: 1.826 ± 0.361
2.83AsnArg: 2.83 ± 0.504
3.012AsnSer: 3.012 ± 0.645
2.373AsnThr: 2.373 ± 0.578
2.373AsnVal: 2.373 ± 0.621
0.73AsnTrp: 0.73 ± 0.278
1.917AsnTyr: 1.917 ± 0.513
0.0AsnXaa: 0.0 ± 0.0
Pro
5.386ProAla: 5.386 ± 0.791
0.822ProCys: 0.822 ± 0.284
3.286ProAsp: 3.286 ± 0.46
5.112ProGlu: 5.112 ± 0.802
2.738ProPhe: 2.738 ± 0.61
4.016ProGly: 4.016 ± 0.657
1.187ProHis: 1.187 ± 0.301
2.008ProIle: 2.008 ± 0.347
2.647ProLys: 2.647 ± 0.908
5.386ProLeu: 5.386 ± 0.868
1.734ProMet: 1.734 ± 0.502
2.191ProAsn: 2.191 ± 0.457
7.394ProPro: 7.394 ± 1.116
3.651ProGln: 3.651 ± 0.587
5.021ProArg: 5.021 ± 0.861
5.568ProSer: 5.568 ± 0.587
3.743ProThr: 3.743 ± 0.722
4.838ProVal: 4.838 ± 0.75
0.822ProTrp: 0.822 ± 0.319
2.282ProTyr: 2.282 ± 0.492
0.0ProXaa: 0.0 ± 0.0
Gln
4.747GlnAla: 4.747 ± 0.744
0.913GlnCys: 0.913 ± 0.349
1.643GlnAsp: 1.643 ± 0.331
2.465GlnGlu: 2.465 ± 0.432
1.095GlnPhe: 1.095 ± 0.398
1.917GlnGly: 1.917 ± 0.449
0.73GlnHis: 0.73 ± 0.192
2.008GlnIle: 2.008 ± 0.428
1.461GlnLys: 1.461 ± 0.347
4.564GlnLeu: 4.564 ± 0.776
1.095GlnMet: 1.095 ± 0.322
1.734GlnAsn: 1.734 ± 0.492
2.83GlnPro: 2.83 ± 0.62
2.373GlnGln: 2.373 ± 0.45
3.286GlnArg: 3.286 ± 0.417
3.195GlnSer: 3.195 ± 0.547
3.104GlnThr: 3.104 ± 0.662
2.282GlnVal: 2.282 ± 0.378
0.365GlnTrp: 0.365 ± 0.198
0.73GlnTyr: 0.73 ± 0.29
0.0GlnXaa: 0.0 ± 0.0
Arg
6.116ArgAla: 6.116 ± 0.942
2.191ArgCys: 2.191 ± 0.524
4.382ArgAsp: 4.382 ± 0.756
4.382ArgGlu: 4.382 ± 0.738
2.738ArgPhe: 2.738 ± 0.424
5.386ArgGly: 5.386 ± 0.919
1.552ArgHis: 1.552 ± 0.357
2.099ArgIle: 2.099 ± 0.411
2.099ArgLys: 2.099 ± 0.334
7.029ArgLeu: 7.029 ± 0.963
1.095ArgMet: 1.095 ± 0.296
3.195ArgAsn: 3.195 ± 0.512
4.655ArgPro: 4.655 ± 1.03
3.104ArgGln: 3.104 ± 0.495
8.946ArgArg: 8.946 ± 2.19
4.016ArgSer: 4.016 ± 0.867
3.377ArgThr: 3.377 ± 0.63
4.655ArgVal: 4.655 ± 0.914
1.278ArgTrp: 1.278 ± 0.302
2.191ArgTyr: 2.191 ± 0.351
0.0ArgXaa: 0.0 ± 0.0
Ser
5.842SerAla: 5.842 ± 0.776
1.461SerCys: 1.461 ± 0.462
2.83SerAsp: 2.83 ± 0.611
3.012SerGlu: 3.012 ± 0.523
2.83SerPhe: 2.83 ± 0.617
4.655SerGly: 4.655 ± 0.822
1.461SerHis: 1.461 ± 0.382
3.195SerIle: 3.195 ± 0.589
1.552SerLys: 1.552 ± 0.405
7.394SerLeu: 7.394 ± 1.185
1.004SerMet: 1.004 ± 0.343
3.104SerAsn: 3.104 ± 0.57
5.021SerPro: 5.021 ± 0.766
2.738SerGln: 2.738 ± 0.392
4.747SerArg: 4.747 ± 0.685
6.116SerSer: 6.116 ± 1.017
4.199SerThr: 4.199 ± 0.649
3.925SerVal: 3.925 ± 0.504
0.639SerTrp: 0.639 ± 0.233
2.282SerTyr: 2.282 ± 0.648
0.0SerXaa: 0.0 ± 0.0
Thr
4.199ThrAla: 4.199 ± 0.818
1.369ThrCys: 1.369 ± 0.41
2.647ThrAsp: 2.647 ± 0.402
1.917ThrGlu: 1.917 ± 0.38
3.195ThrPhe: 3.195 ± 0.696
3.651ThrGly: 3.651 ± 0.73
1.095ThrHis: 1.095 ± 0.303
3.469ThrIle: 3.469 ± 0.979
2.008ThrLys: 2.008 ± 0.335
8.398ThrLeu: 8.398 ± 1.026
1.095ThrMet: 1.095 ± 0.28
1.826ThrAsn: 1.826 ± 0.505
4.108ThrPro: 4.108 ± 0.642
2.556ThrGln: 2.556 ± 0.439
2.647ThrArg: 2.647 ± 0.365
2.556ThrSer: 2.556 ± 0.535
3.56ThrThr: 3.56 ± 0.592
4.108ThrVal: 4.108 ± 0.701
1.095ThrTrp: 1.095 ± 0.269
2.647ThrTyr: 2.647 ± 0.579
0.0ThrXaa: 0.0 ± 0.0
Val
4.747ValAla: 4.747 ± 0.677
1.095ValCys: 1.095 ± 0.251
3.651ValAsp: 3.651 ± 0.741
4.655ValGlu: 4.655 ± 0.824
2.282ValPhe: 2.282 ± 0.487
3.377ValGly: 3.377 ± 0.615
1.004ValHis: 1.004 ± 0.286
2.465ValIle: 2.465 ± 0.424
2.282ValLys: 2.282 ± 0.466
5.66ValLeu: 5.66 ± 0.577
1.278ValMet: 1.278 ± 0.327
2.556ValAsn: 2.556 ± 0.423
4.747ValPro: 4.747 ± 0.713
3.104ValGln: 3.104 ± 0.551
4.838ValArg: 4.838 ± 1.037
4.473ValSer: 4.473 ± 0.643
4.29ValThr: 4.29 ± 0.345
4.382ValVal: 4.382 ± 0.861
1.095ValTrp: 1.095 ± 0.316
3.56ValTyr: 3.56 ± 0.541
0.0ValXaa: 0.0 ± 0.0
Trp
0.365TrpAla: 0.365 ± 0.161
0.183TrpCys: 0.183 ± 0.132
0.639TrpAsp: 0.639 ± 0.183
1.004TrpGlu: 1.004 ± 0.369
0.456TrpPhe: 0.456 ± 0.288
0.822TrpGly: 0.822 ± 0.279
0.183TrpHis: 0.183 ± 0.149
0.456TrpIle: 0.456 ± 0.198
1.004TrpLys: 1.004 ± 0.327
1.461TrpLeu: 1.461 ± 0.396
0.365TrpMet: 0.365 ± 0.167
0.73TrpAsn: 0.73 ± 0.266
0.73TrpPro: 0.73 ± 0.205
0.639TrpGln: 0.639 ± 0.219
0.639TrpArg: 0.639 ± 0.235
1.461TrpSer: 1.461 ± 0.447
1.278TrpThr: 1.278 ± 0.311
0.365TrpVal: 0.365 ± 0.196
0.183TrpTrp: 0.183 ± 0.117
0.456TrpTyr: 0.456 ± 0.192
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.191TyrAla: 2.191 ± 0.418
0.639TyrCys: 0.639 ± 0.215
1.552TyrAsp: 1.552 ± 0.504
2.191TyrGlu: 2.191 ± 0.569
2.282TyrPhe: 2.282 ± 0.583
2.099TyrGly: 2.099 ± 0.477
0.822TyrHis: 0.822 ± 0.284
0.913TyrIle: 0.913 ± 0.316
1.734TyrLys: 1.734 ± 0.517
4.016TyrLeu: 4.016 ± 0.477
0.822TyrMet: 0.822 ± 0.311
1.552TyrAsn: 1.552 ± 0.573
2.008TyrPro: 2.008 ± 0.391
2.008TyrGln: 2.008 ± 0.426
2.099TyrArg: 2.099 ± 0.356
2.556TyrSer: 2.556 ± 0.641
1.826TyrThr: 1.826 ± 0.368
2.008TyrVal: 2.008 ± 0.458
0.456TyrTrp: 0.456 ± 0.171
0.822TyrTyr: 0.822 ± 0.337
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 32 proteins (10956 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski