Amino acid dipepetide frequency for Aedes alboannulatus toti-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.37AlaAla: 7.37 ± 1.671
1.134AlaCys: 1.134 ± 0.068
2.834AlaAsp: 2.834 ± 0.242
4.535AlaGlu: 4.535 ± 1.092
0.567AlaPhe: 0.567 ± 0.377
5.669AlaGly: 5.669 ± 1.981
1.134AlaHis: 1.134 ± 0.068
6.803AlaIle: 6.803 ± 2.06
1.701AlaLys: 1.701 ± 0.31
10.204AlaLeu: 10.204 ± 1.429
2.834AlaMet: 2.834 ± 1.064
1.701AlaAsn: 1.701 ± 0.512
5.102AlaPro: 5.102 ± 4.001
3.401AlaGln: 3.401 ± 1.024
6.236AlaArg: 6.236 ± 1.604
10.204AlaSer: 10.204 ± 1.035
5.669AlaThr: 5.669 ± 0.338
7.37AlaVal: 7.37 ± 0.028
1.134AlaTrp: 1.134 ± 0.068
1.134AlaTyr: 1.134 ± 0.754
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.567CysCys: 0.567 ± 0.377
1.134CysAsp: 1.134 ± 0.068
0.567CysGlu: 0.567 ± 0.445
1.134CysPhe: 1.134 ± 0.889
1.134CysGly: 1.134 ± 0.889
0.0CysHis: 0.0 ± 0.0
2.834CysIle: 2.834 ± 1.064
1.134CysLys: 1.134 ± 0.754
2.834CysLeu: 2.834 ± 1.064
0.567CysMet: 0.567 ± 0.377
1.134CysAsn: 1.134 ± 0.754
0.567CysPro: 0.567 ± 0.445
0.0CysGln: 0.0 ± 0.0
3.968CysArg: 3.968 ± 0.996
1.134CysSer: 1.134 ± 0.068
0.0CysThr: 0.0 ± 0.0
0.567CysVal: 0.567 ± 0.377
0.0CysTrp: 0.0 ± 0.0
1.701CysTyr: 1.701 ± 1.334
0.0CysXaa: 0.0 ± 0.0
Asp
3.968AspAla: 3.968 ± 0.174
0.0AspCys: 0.0 ± 0.0
2.834AspAsp: 2.834 ± 0.58
5.102AspGlu: 5.102 ± 0.929
2.268AspPhe: 2.268 ± 0.135
1.134AspGly: 1.134 ± 0.068
0.0AspHis: 0.0 ± 0.0
3.968AspIle: 3.968 ± 1.469
3.401AspLys: 3.401 ± 0.619
6.236AspLeu: 6.236 ± 1.604
2.834AspMet: 2.834 ± 0.242
2.268AspAsn: 2.268 ± 0.135
0.567AspPro: 0.567 ± 0.377
0.0AspGln: 0.0 ± 0.0
1.134AspArg: 1.134 ± 0.068
2.834AspSer: 2.834 ± 1.885
1.134AspThr: 1.134 ± 0.889
5.102AspVal: 5.102 ± 0.715
2.834AspTrp: 2.834 ± 0.242
3.401AspTyr: 3.401 ± 0.619
0.0AspXaa: 0.0 ± 0.0
Glu
3.968GluAla: 3.968 ± 0.996
0.567GluCys: 0.567 ± 0.377
1.134GluAsp: 1.134 ± 0.754
6.803GluGlu: 6.803 ± 2.06
3.968GluPhe: 3.968 ± 2.639
3.401GluGly: 3.401 ± 0.203
1.134GluHis: 1.134 ± 0.889
0.567GluIle: 0.567 ± 0.445
4.535GluLys: 4.535 ± 2.735
3.968GluLeu: 3.968 ± 0.996
1.701GluMet: 1.701 ± 1.131
0.0GluAsn: 0.0 ± 0.0
3.968GluPro: 3.968 ± 1.469
0.567GluGln: 0.567 ± 0.445
3.968GluArg: 3.968 ± 2.639
4.535GluSer: 4.535 ± 0.551
3.401GluThr: 3.401 ± 1.846
5.102GluVal: 5.102 ± 0.715
2.268GluTrp: 2.268 ± 0.687
1.701GluTyr: 1.701 ± 0.31
0.0GluXaa: 0.0 ± 0.0
Phe
3.968PheAla: 3.968 ± 2.29
0.0PheCys: 0.0 ± 0.0
4.535PheAsp: 4.535 ± 0.551
3.401PheGlu: 3.401 ± 1.441
1.134PhePhe: 1.134 ± 0.068
2.268PheGly: 2.268 ± 0.957
0.0PheHis: 0.0 ± 0.0
1.701PheIle: 1.701 ± 0.512
1.701PheLys: 1.701 ± 1.131
3.401PheLeu: 3.401 ± 0.203
0.567PheMet: 0.567 ± 0.445
2.834PheAsn: 2.834 ± 0.58
0.567PhePro: 0.567 ± 0.377
1.701PheGln: 1.701 ± 1.131
0.0PheArg: 0.0 ± 0.0
2.834PheSer: 2.834 ± 0.242
1.134PheThr: 1.134 ± 0.068
2.268PheVal: 2.268 ± 0.135
0.567PheTrp: 0.567 ± 0.377
1.134PheTyr: 1.134 ± 0.068
0.0PheXaa: 0.0 ± 0.0
Gly
5.669GlyAla: 5.669 ± 1.981
2.268GlyCys: 2.268 ± 0.135
2.268GlyAsp: 2.268 ± 0.687
2.834GlyGlu: 2.834 ± 1.401
4.535GlyPhe: 4.535 ± 1.092
3.968GlyGly: 3.968 ± 0.174
1.701GlyHis: 1.701 ± 0.512
2.268GlyIle: 2.268 ± 0.957
2.268GlyLys: 2.268 ± 0.135
9.637GlyLeu: 9.637 ± 0.658
3.968GlyMet: 3.968 ± 0.647
2.268GlyAsn: 2.268 ± 0.135
3.968GlyPro: 3.968 ± 1.469
2.834GlyGln: 2.834 ± 0.58
3.401GlyArg: 3.401 ± 0.203
1.701GlySer: 1.701 ± 0.31
2.834GlyThr: 2.834 ± 0.242
4.535GlyVal: 4.535 ± 1.092
0.567GlyTrp: 0.567 ± 0.377
2.268GlyTyr: 2.268 ± 0.135
0.0GlyXaa: 0.0 ± 0.0
His
1.134HisAla: 1.134 ± 0.068
1.701HisCys: 1.701 ± 0.31
1.701HisAsp: 1.701 ± 0.512
0.567HisGlu: 0.567 ± 0.445
1.134HisPhe: 1.134 ± 0.889
1.134HisGly: 1.134 ± 0.068
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.567HisLys: 0.567 ± 0.377
1.134HisLeu: 1.134 ± 0.068
0.567HisMet: 0.567 ± 0.377
0.0HisAsn: 0.0 ± 0.0
3.968HisPro: 3.968 ± 0.996
1.134HisGln: 1.134 ± 0.068
0.0HisArg: 0.0 ± 0.0
1.134HisSer: 1.134 ± 0.068
0.567HisThr: 0.567 ± 0.377
2.268HisVal: 2.268 ± 0.135
0.567HisTrp: 0.567 ± 0.377
1.134HisTyr: 1.134 ± 0.889
0.0HisXaa: 0.0 ± 0.0
Ile
5.669IleAla: 5.669 ± 0.338
1.134IleCys: 1.134 ± 0.754
4.535IleAsp: 4.535 ± 0.551
3.968IleGlu: 3.968 ± 1.818
0.0IlePhe: 0.0 ± 0.0
3.968IleGly: 3.968 ± 1.469
2.268IleHis: 2.268 ± 0.135
5.669IleIle: 5.669 ± 0.484
3.401IleLys: 3.401 ± 0.203
2.834IleLeu: 2.834 ± 0.58
1.701IleMet: 1.701 ± 0.512
2.834IleAsn: 2.834 ± 0.58
2.834IlePro: 2.834 ± 0.242
2.268IleGln: 2.268 ± 0.957
3.401IleArg: 3.401 ± 0.203
5.669IleSer: 5.669 ± 2.127
2.834IleThr: 2.834 ± 1.401
3.401IleVal: 3.401 ± 1.441
2.268IleTrp: 2.268 ± 0.135
1.134IleTyr: 1.134 ± 0.068
0.0IleXaa: 0.0 ± 0.0
Lys
8.503LysAla: 8.503 ± 0.726
0.567LysCys: 0.567 ± 0.377
1.134LysAsp: 1.134 ± 0.068
5.669LysGlu: 5.669 ± 2.803
1.134LysPhe: 1.134 ± 0.754
1.701LysGly: 1.701 ± 0.31
0.567LysHis: 0.567 ± 0.377
1.701LysIle: 1.701 ± 0.31
2.268LysLys: 2.268 ± 0.135
3.401LysLeu: 3.401 ± 0.619
1.701LysMet: 1.701 ± 0.31
1.134LysAsn: 1.134 ± 0.068
2.268LysPro: 2.268 ± 0.687
0.567LysGln: 0.567 ± 0.377
2.268LysArg: 2.268 ± 0.687
3.401LysSer: 3.401 ± 1.441
2.834LysThr: 2.834 ± 1.064
2.834LysVal: 2.834 ± 0.58
1.134LysTrp: 1.134 ± 0.754
0.567LysTyr: 0.567 ± 0.377
0.0LysXaa: 0.0 ± 0.0
Leu
6.236LeuAla: 6.236 ± 2.426
0.567LeuCys: 0.567 ± 0.445
2.834LeuAsp: 2.834 ± 1.064
3.401LeuGlu: 3.401 ± 1.441
2.834LeuPhe: 2.834 ± 0.242
5.669LeuGly: 5.669 ± 0.338
2.834LeuHis: 2.834 ± 0.242
4.535LeuIle: 4.535 ± 1.373
2.268LeuLys: 2.268 ± 0.957
7.937LeuLeu: 7.937 ± 2.814
1.134LeuMet: 1.134 ± 0.889
7.37LeuAsn: 7.37 ± 0.793
3.401LeuPro: 3.401 ± 0.203
1.701LeuGln: 1.701 ± 0.512
6.803LeuArg: 6.803 ± 2.06
8.503LeuSer: 8.503 ± 0.096
4.535LeuThr: 4.535 ± 2.735
9.637LeuVal: 9.637 ± 0.163
3.401LeuTrp: 3.401 ± 1.441
3.968LeuTyr: 3.968 ± 0.174
0.0LeuXaa: 0.0 ± 0.0
Met
2.834MetAla: 2.834 ± 0.58
1.134MetCys: 1.134 ± 0.068
2.834MetAsp: 2.834 ± 0.58
1.134MetGlu: 1.134 ± 0.068
2.834MetPhe: 2.834 ± 1.064
1.701MetGly: 1.701 ± 0.512
1.134MetHis: 1.134 ± 0.068
0.567MetIle: 0.567 ± 0.377
0.567MetLys: 0.567 ± 0.377
1.701MetLeu: 1.701 ± 0.31
0.0MetMet: 0.0 ± 0.0
1.134MetAsn: 1.134 ± 0.754
0.567MetPro: 0.567 ± 0.377
1.701MetGln: 1.701 ± 1.131
1.701MetArg: 1.701 ± 0.512
5.102MetSer: 5.102 ± 0.929
1.701MetThr: 1.701 ± 0.512
2.834MetVal: 2.834 ± 0.242
0.0MetTrp: 0.0 ± 0.0
0.567MetTyr: 0.567 ± 0.445
0.0MetXaa: 0.0 ± 0.0
Asn
0.567AsnAla: 0.567 ± 0.377
0.567AsnCys: 0.567 ± 0.377
2.268AsnAsp: 2.268 ± 0.135
2.834AsnGlu: 2.834 ± 0.242
2.834AsnPhe: 2.834 ± 0.242
1.701AsnGly: 1.701 ± 1.131
0.0AsnHis: 0.0 ± 0.0
4.535AsnIle: 4.535 ± 0.27
3.401AsnLys: 3.401 ± 0.203
3.401AsnLeu: 3.401 ± 0.619
1.134AsnMet: 1.134 ± 0.244
0.567AsnAsn: 0.567 ± 0.377
1.701AsnPro: 1.701 ± 0.31
1.134AsnGln: 1.134 ± 0.068
2.268AsnArg: 2.268 ± 0.135
1.701AsnSer: 1.701 ± 0.31
1.701AsnThr: 1.701 ± 0.31
3.401AsnVal: 3.401 ± 0.203
0.567AsnTrp: 0.567 ± 0.377
1.134AsnTyr: 1.134 ± 0.068
0.0AsnXaa: 0.0 ± 0.0
Pro
5.669ProAla: 5.669 ± 1.159
0.567ProCys: 0.567 ± 0.377
4.535ProAsp: 4.535 ± 0.551
0.0ProGlu: 0.0 ± 0.0
1.701ProPhe: 1.701 ± 0.512
2.834ProGly: 2.834 ± 0.58
2.268ProHis: 2.268 ± 0.957
3.401ProIle: 3.401 ± 0.619
1.134ProLys: 1.134 ± 0.068
3.968ProLeu: 3.968 ± 1.469
1.134ProMet: 1.134 ± 0.754
1.134ProAsn: 1.134 ± 0.068
2.834ProPro: 2.834 ± 1.401
2.268ProGln: 2.268 ± 0.135
4.535ProArg: 4.535 ± 0.551
3.401ProSer: 3.401 ± 0.203
1.701ProThr: 1.701 ± 0.512
3.401ProVal: 3.401 ± 2.667
0.0ProTrp: 0.0 ± 0.0
2.834ProTyr: 2.834 ± 1.401
0.0ProXaa: 0.0 ± 0.0
Gln
3.401GlnAla: 3.401 ± 0.619
0.567GlnCys: 0.567 ± 0.445
2.268GlnAsp: 2.268 ± 0.957
0.0GlnGlu: 0.0 ± 0.0
1.134GlnPhe: 1.134 ± 0.889
1.701GlnGly: 1.701 ± 0.31
1.701GlnHis: 1.701 ± 0.512
1.701GlnIle: 1.701 ± 0.31
0.567GlnLys: 0.567 ± 0.377
1.701GlnLeu: 1.701 ± 0.31
1.134GlnMet: 1.134 ± 0.754
1.701GlnAsn: 1.701 ± 0.31
3.401GlnPro: 3.401 ± 1.846
1.134GlnGln: 1.134 ± 0.068
1.701GlnArg: 1.701 ± 0.31
3.968GlnSer: 3.968 ± 1.818
1.134GlnThr: 1.134 ± 0.889
0.567GlnVal: 0.567 ± 0.445
0.567GlnTrp: 0.567 ± 0.377
0.567GlnTyr: 0.567 ± 0.445
0.0GlnXaa: 0.0 ± 0.0
Arg
7.937ArgAla: 7.937 ± 1.992
1.701ArgCys: 1.701 ± 0.512
3.401ArgAsp: 3.401 ± 1.024
3.401ArgGlu: 3.401 ± 0.619
1.134ArgPhe: 1.134 ± 0.068
4.535ArgGly: 4.535 ± 0.551
0.567ArgHis: 0.567 ± 0.377
4.535ArgIle: 4.535 ± 0.27
3.968ArgLys: 3.968 ± 1.818
5.102ArgLeu: 5.102 ± 0.107
2.268ArgMet: 2.268 ± 0.135
0.567ArgAsn: 0.567 ± 0.377
0.567ArgPro: 0.567 ± 0.377
1.701ArgGln: 1.701 ± 0.512
4.535ArgArg: 4.535 ± 0.551
3.968ArgSer: 3.968 ± 0.647
2.834ArgThr: 2.834 ± 0.242
5.669ArgVal: 5.669 ± 1.306
1.134ArgTrp: 1.134 ± 0.068
0.567ArgTyr: 0.567 ± 0.377
0.0ArgXaa: 0.0 ± 0.0
Ser
3.968SerAla: 3.968 ± 0.647
3.401SerCys: 3.401 ± 0.203
4.535SerAsp: 4.535 ± 1.373
3.968SerGlu: 3.968 ± 0.996
1.134SerPhe: 1.134 ± 0.889
7.37SerGly: 7.37 ± 0.028
1.134SerHis: 1.134 ± 0.754
4.535SerIle: 4.535 ± 0.551
5.669SerLys: 5.669 ± 2.127
6.236SerLeu: 6.236 ± 0.039
3.401SerMet: 3.401 ± 1.441
3.968SerAsn: 3.968 ± 2.639
3.401SerPro: 3.401 ± 0.619
1.701SerGln: 1.701 ± 0.31
3.401SerArg: 3.401 ± 1.441
9.637SerSer: 9.637 ± 0.658
6.236SerThr: 6.236 ± 2.426
5.669SerVal: 5.669 ± 0.338
1.701SerTrp: 1.701 ± 0.31
2.268SerTyr: 2.268 ± 1.508
0.0SerXaa: 0.0 ± 0.0
Thr
5.102ThrAla: 5.102 ± 0.715
0.567ThrCys: 0.567 ± 0.445
1.134ThrAsp: 1.134 ± 0.068
3.401ThrGlu: 3.401 ± 0.203
2.268ThrPhe: 2.268 ± 0.957
2.268ThrGly: 2.268 ± 0.135
0.567ThrHis: 0.567 ± 0.445
3.401ThrIle: 3.401 ± 0.203
1.134ThrLys: 1.134 ± 0.754
5.669ThrLeu: 5.669 ± 0.338
1.701ThrMet: 1.701 ± 1.334
2.268ThrAsn: 2.268 ± 0.135
1.134ThrPro: 1.134 ± 0.889
1.134ThrGln: 1.134 ± 0.754
3.401ThrArg: 3.401 ± 0.203
5.102ThrSer: 5.102 ± 1.536
2.834ThrThr: 2.834 ± 1.401
1.134ThrVal: 1.134 ± 0.068
1.701ThrTrp: 1.701 ± 1.334
1.134ThrTyr: 1.134 ± 0.754
0.0ThrXaa: 0.0 ± 0.0
Val
7.37ValAla: 7.37 ± 0.028
2.834ValCys: 2.834 ± 0.242
2.834ValAsp: 2.834 ± 1.401
3.968ValGlu: 3.968 ± 0.174
2.268ValPhe: 2.268 ± 1.508
7.37ValGly: 7.37 ± 0.85
1.701ValHis: 1.701 ± 0.31
5.102ValIle: 5.102 ± 3.18
3.968ValLys: 3.968 ± 0.996
5.102ValLeu: 5.102 ± 0.929
1.134ValMet: 1.134 ± 0.889
2.834ValAsn: 2.834 ± 0.242
6.236ValPro: 6.236 ± 0.782
4.535ValGln: 4.535 ± 1.092
5.102ValArg: 5.102 ± 1.536
3.968ValSer: 3.968 ± 0.996
2.834ValThr: 2.834 ± 1.885
3.968ValVal: 3.968 ± 1.469
1.134ValTrp: 1.134 ± 0.068
0.567ValTyr: 0.567 ± 0.445
0.0ValXaa: 0.0 ± 0.0
Trp
1.134TrpAla: 1.134 ± 0.068
0.567TrpCys: 0.567 ± 0.377
1.701TrpAsp: 1.701 ± 0.512
1.134TrpGlu: 1.134 ± 0.754
0.0TrpPhe: 0.0 ± 0.0
2.268TrpGly: 2.268 ± 0.957
1.134TrpHis: 1.134 ± 0.754
2.268TrpIle: 2.268 ± 0.687
1.134TrpLys: 1.134 ± 0.068
1.134TrpLeu: 1.134 ± 0.754
0.567TrpMet: 0.567 ± 0.377
0.0TrpAsn: 0.0 ± 0.0
1.701TrpPro: 1.701 ± 0.512
0.0TrpGln: 0.0 ± 0.0
1.134TrpArg: 1.134 ± 0.754
1.701TrpSer: 1.701 ± 0.512
0.567TrpThr: 0.567 ± 0.377
2.834TrpVal: 2.834 ± 1.064
1.134TrpTrp: 1.134 ± 0.889
0.567TrpTyr: 0.567 ± 0.377
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.268TyrAla: 2.268 ± 0.957
0.567TyrCys: 0.567 ± 0.377
0.567TyrAsp: 0.567 ± 0.445
0.567TyrGlu: 0.567 ± 0.377
1.701TyrPhe: 1.701 ± 0.512
3.968TyrGly: 3.968 ± 1.469
0.567TyrHis: 0.567 ± 0.377
1.701TyrIle: 1.701 ± 0.31
0.567TyrLys: 0.567 ± 0.377
3.968TyrLeu: 3.968 ± 0.647
1.134TyrMet: 1.134 ± 0.226
1.701TyrAsn: 1.701 ± 0.512
0.567TyrPro: 0.567 ± 0.377
1.134TyrGln: 1.134 ± 0.754
1.134TyrArg: 1.134 ± 0.068
2.834TyrSer: 2.834 ± 1.064
0.567TyrThr: 0.567 ± 0.377
2.268TyrVal: 2.268 ± 0.135
0.0TyrTrp: 0.0 ± 0.0
0.567TyrTyr: 0.567 ± 0.445
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1765 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski