Amino acid dipepetide frequency for Changjiang tombus-like virus 20

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.43AlaAla: 4.43 ± 0.106
0.0AlaCys: 0.0 ± 0.0
1.899AlaAsp: 1.899 ± 0.109
3.165AlaGlu: 3.165 ± 1.622
3.797AlaPhe: 3.797 ± 0.864
3.797AlaGly: 3.797 ± 1.301
0.0AlaHis: 0.0 ± 0.0
5.696AlaIle: 5.696 ± 0.755
4.43AlaLys: 4.43 ± 0.977
5.063AlaLeu: 5.063 ± 3.901
2.532AlaMet: 2.532 ± 0.731
2.532AlaAsn: 2.532 ± 0.868
5.063AlaPro: 5.063 ± 0.43
0.633AlaGln: 0.633 ± 0.324
3.165AlaArg: 3.165 ± 0.54
8.228AlaSer: 8.228 ± 2.278
8.228AlaThr: 8.228 ± 2.278
4.43AlaVal: 4.43 ± 2.06
0.633AlaTrp: 0.633 ± 0.324
1.266AlaTyr: 1.266 ± 0.649
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.633CysCys: 0.633 ± 0.324
0.633CysAsp: 0.633 ± 0.758
1.266CysGlu: 1.266 ± 0.434
1.266CysPhe: 1.266 ± 0.649
1.266CysGly: 1.266 ± 0.434
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.266CysLeu: 1.266 ± 0.649
0.0CysMet: 0.0 ± 0.0
1.266CysAsn: 1.266 ± 0.649
0.633CysPro: 0.633 ± 0.324
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
3.165CysSer: 3.165 ± 0.543
0.633CysThr: 0.633 ± 0.324
0.633CysVal: 0.633 ± 0.324
0.0CysTrp: 0.0 ± 0.0
0.633CysTyr: 0.633 ± 0.324
0.0CysXaa: 0.0 ± 0.0
Asp
3.797AspAla: 3.797 ± 0.219
1.266AspCys: 1.266 ± 0.649
2.532AspAsp: 2.532 ± 0.868
2.532AspGlu: 2.532 ± 1.298
3.165AspPhe: 3.165 ± 0.54
6.329AspGly: 6.329 ± 1.079
0.633AspHis: 0.633 ± 0.324
1.266AspIle: 1.266 ± 0.649
4.43AspLys: 4.43 ± 0.106
3.165AspLeu: 3.165 ± 0.54
1.899AspMet: 1.899 ± 0.973
3.797AspAsn: 3.797 ± 0.219
1.266AspPro: 1.266 ± 0.434
1.266AspGln: 1.266 ± 0.434
1.266AspArg: 1.266 ± 0.649
4.43AspSer: 4.43 ± 0.106
5.063AspThr: 5.063 ± 1.513
1.899AspVal: 1.899 ± 0.973
0.0AspTrp: 0.0 ± 0.0
1.899AspTyr: 1.899 ± 0.109
0.0AspXaa: 0.0 ± 0.0
Glu
3.165GluAla: 3.165 ± 0.54
0.0GluCys: 0.0 ± 0.0
3.165GluAsp: 3.165 ± 1.622
2.532GluGlu: 2.532 ± 0.215
1.899GluPhe: 1.899 ± 0.109
3.797GluGly: 3.797 ± 1.947
1.266GluHis: 1.266 ± 0.649
1.899GluIle: 1.899 ± 0.109
3.165GluLys: 3.165 ± 0.54
4.43GluLeu: 4.43 ± 2.271
0.633GluMet: 0.633 ± 0.324
0.0GluAsn: 0.0 ± 0.0
2.532GluPro: 2.532 ± 0.868
0.0GluGln: 0.0 ± 0.0
1.899GluArg: 1.899 ± 0.973
2.532GluSer: 2.532 ± 0.215
3.797GluThr: 3.797 ± 0.864
5.063GluVal: 5.063 ± 1.513
0.633GluTrp: 0.633 ± 0.758
2.532GluTyr: 2.532 ± 0.215
0.0GluXaa: 0.0 ± 0.0
Phe
1.899PheAla: 1.899 ± 1.192
0.633PheCys: 0.633 ± 0.324
1.899PheAsp: 1.899 ± 1.192
1.266PheGlu: 1.266 ± 0.649
1.266PhePhe: 1.266 ± 0.649
1.899PheGly: 1.899 ± 0.973
0.0PheHis: 0.0 ± 0.0
1.899PheIle: 1.899 ± 1.192
2.532PheLys: 2.532 ± 0.215
3.797PheLeu: 3.797 ± 0.864
1.266PheMet: 1.266 ± 0.649
3.165PheAsn: 3.165 ± 0.54
0.633PhePro: 0.633 ± 0.324
1.266PheGln: 1.266 ± 0.649
2.532PheArg: 2.532 ± 1.95
3.165PheSer: 3.165 ± 0.543
4.43PheThr: 4.43 ± 0.106
1.899PheVal: 1.899 ± 0.973
0.633PheTrp: 0.633 ± 0.324
1.266PheTyr: 1.266 ± 0.434
0.0PheXaa: 0.0 ± 0.0
Gly
3.797GlyAla: 3.797 ± 0.219
0.633GlyCys: 0.633 ± 0.324
5.063GlyAsp: 5.063 ± 0.43
3.797GlyGlu: 3.797 ± 1.947
3.165GlyPhe: 3.165 ± 0.54
4.43GlyGly: 4.43 ± 0.106
1.899GlyHis: 1.899 ± 0.973
3.165GlyIle: 3.165 ± 0.54
4.43GlyLys: 4.43 ± 0.106
2.532GlyLeu: 2.532 ± 0.215
2.532GlyMet: 2.532 ± 0.215
6.962GlyAsn: 6.962 ± 1.845
6.329GlyPro: 6.329 ± 0.003
1.266GlyGln: 1.266 ± 0.434
3.165GlyArg: 3.165 ± 1.622
2.532GlySer: 2.532 ± 0.868
5.696GlyThr: 5.696 ± 2.493
5.063GlyVal: 5.063 ± 1.735
0.0GlyTrp: 0.0 ± 0.0
4.43GlyTyr: 4.43 ± 0.106
0.0GlyXaa: 0.0 ± 0.0
His
0.633HisAla: 0.633 ± 0.324
0.633HisCys: 0.633 ± 0.324
1.266HisAsp: 1.266 ± 0.434
3.165HisGlu: 3.165 ± 1.622
0.0HisPhe: 0.0 ± 0.0
1.266HisGly: 1.266 ± 0.434
1.266HisHis: 1.266 ± 0.649
1.266HisIle: 1.266 ± 0.649
1.266HisLys: 1.266 ± 0.649
1.899HisLeu: 1.899 ± 0.973
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.266HisPro: 1.266 ± 0.649
2.532HisGln: 2.532 ± 1.298
0.0HisArg: 0.0 ± 0.0
2.532HisSer: 2.532 ± 0.215
0.633HisThr: 0.633 ± 0.324
0.633HisVal: 0.633 ± 0.324
1.266HisTrp: 1.266 ± 0.649
2.532HisTyr: 2.532 ± 0.215
0.0HisXaa: 0.0 ± 0.0
Ile
3.165IleAla: 3.165 ± 0.543
0.0IleCys: 0.0 ± 0.0
1.899IleAsp: 1.899 ± 1.192
4.43IleGlu: 4.43 ± 1.189
1.266IlePhe: 1.266 ± 0.434
2.532IleGly: 2.532 ± 0.215
1.899IleHis: 1.899 ± 0.109
2.532IleIle: 2.532 ± 0.868
5.063IleLys: 5.063 ± 2.596
3.165IleLeu: 3.165 ± 0.543
0.633IleMet: 0.633 ± 0.324
3.165IleAsn: 3.165 ± 0.543
3.165IlePro: 3.165 ± 0.543
1.899IleGln: 1.899 ± 1.192
1.266IleArg: 1.266 ± 0.649
2.532IleSer: 2.532 ± 0.868
2.532IleThr: 2.532 ± 1.95
5.696IleVal: 5.696 ± 2.493
0.0IleTrp: 0.0 ± 0.0
1.899IleTyr: 1.899 ± 0.109
0.0IleXaa: 0.0 ± 0.0
Lys
3.797LysAla: 3.797 ± 1.301
1.266LysCys: 1.266 ± 0.649
3.797LysAsp: 3.797 ± 0.864
5.063LysGlu: 5.063 ± 0.43
1.899LysPhe: 1.899 ± 0.109
1.266LysGly: 1.266 ± 0.649
2.532LysHis: 2.532 ± 1.298
2.532LysIle: 2.532 ± 1.298
1.899LysLys: 1.899 ± 0.973
5.063LysLeu: 5.063 ± 1.513
1.266LysMet: 1.266 ± 0.649
8.228LysAsn: 8.228 ± 0.113
2.532LysPro: 2.532 ± 1.298
6.962LysGln: 6.962 ± 1.404
4.43LysArg: 4.43 ± 0.106
2.532LysSer: 2.532 ± 1.298
5.063LysThr: 5.063 ± 1.513
3.797LysVal: 3.797 ± 0.864
1.266LysTrp: 1.266 ± 0.649
1.266LysTyr: 1.266 ± 0.649
0.0LysXaa: 0.0 ± 0.0
Leu
5.696LeuAla: 5.696 ± 1.411
0.0LeuCys: 0.0 ± 0.0
5.063LeuAsp: 5.063 ± 1.513
4.43LeuGlu: 4.43 ± 1.189
1.899LeuPhe: 1.899 ± 0.109
2.532LeuGly: 2.532 ± 0.215
3.165LeuHis: 3.165 ± 0.54
3.797LeuIle: 3.797 ± 0.864
5.063LeuLys: 5.063 ± 2.596
3.797LeuLeu: 3.797 ± 0.864
1.899LeuMet: 1.899 ± 0.973
2.532LeuAsn: 2.532 ± 0.868
3.165LeuPro: 3.165 ± 0.543
1.899LeuGln: 1.899 ± 0.109
3.797LeuArg: 3.797 ± 1.301
8.228LeuSer: 8.228 ± 1.196
3.797LeuThr: 3.797 ± 0.219
6.329LeuVal: 6.329 ± 3.245
0.633LeuTrp: 0.633 ± 0.758
3.797LeuTyr: 3.797 ± 1.301
0.0LeuXaa: 0.0 ± 0.0
Met
2.532MetAla: 2.532 ± 1.298
1.266MetCys: 1.266 ± 0.434
1.899MetAsp: 1.899 ± 0.973
0.633MetGlu: 0.633 ± 0.324
0.633MetPhe: 0.633 ± 0.324
3.165MetGly: 3.165 ± 0.54
1.266MetHis: 1.266 ± 0.649
0.0MetIle: 0.0 ± 0.0
1.899MetLys: 1.899 ± 0.973
0.633MetLeu: 0.633 ± 0.758
0.633MetMet: 0.633 ± 0.324
1.899MetAsn: 1.899 ± 0.109
1.266MetPro: 1.266 ± 0.649
0.633MetGln: 0.633 ± 0.758
1.266MetArg: 1.266 ± 0.434
0.633MetSer: 0.633 ± 0.758
1.899MetThr: 1.899 ± 0.973
2.532MetVal: 2.532 ± 0.868
0.0MetTrp: 0.0 ± 0.0
0.633MetTyr: 0.633 ± 0.324
0.0MetXaa: 0.0 ± 0.0
Asn
5.696AsnAla: 5.696 ± 1.411
0.633AsnCys: 0.633 ± 0.758
2.532AsnAsp: 2.532 ± 1.298
0.633AsnGlu: 0.633 ± 0.324
0.633AsnPhe: 0.633 ± 0.324
3.797AsnGly: 3.797 ± 0.219
1.899AsnHis: 1.899 ± 0.973
1.266AsnIle: 1.266 ± 0.434
2.532AsnLys: 2.532 ± 1.298
5.063AsnLeu: 5.063 ± 0.43
1.899AsnMet: 1.899 ± 0.109
3.165AsnAsn: 3.165 ± 0.543
2.532AsnPro: 2.532 ± 1.95
1.266AsnGln: 1.266 ± 0.434
4.43AsnArg: 4.43 ± 2.271
6.962AsnSer: 6.962 ± 1.845
7.595AsnThr: 7.595 ± 0.437
2.532AsnVal: 2.532 ± 0.215
0.0AsnTrp: 0.0 ± 0.0
4.43AsnTyr: 4.43 ± 0.977
0.0AsnXaa: 0.0 ± 0.0
Pro
2.532ProAla: 2.532 ± 0.868
0.633ProCys: 0.633 ± 0.324
1.899ProAsp: 1.899 ± 0.973
1.266ProGlu: 1.266 ± 0.434
1.266ProPhe: 1.266 ± 0.434
5.696ProGly: 5.696 ± 1.838
0.633ProHis: 0.633 ± 0.324
3.165ProIle: 3.165 ± 0.543
3.797ProLys: 3.797 ± 1.947
6.329ProLeu: 6.329 ± 1.079
0.0ProMet: 0.0 ± 0.0
2.532ProAsn: 2.532 ± 0.868
1.266ProPro: 1.266 ± 0.649
1.899ProGln: 1.899 ± 1.192
3.797ProArg: 3.797 ± 0.219
4.43ProSer: 4.43 ± 4.225
4.43ProThr: 4.43 ± 3.142
1.266ProVal: 1.266 ± 0.649
0.633ProTrp: 0.633 ± 0.324
1.899ProTyr: 1.899 ± 0.973
0.0ProXaa: 0.0 ± 0.0
Gln
1.266GlnAla: 1.266 ± 1.517
0.0GlnCys: 0.0 ± 0.0
1.266GlnAsp: 1.266 ± 0.649
2.532GlnGlu: 2.532 ± 0.868
1.899GlnPhe: 1.899 ± 0.109
1.899GlnGly: 1.899 ± 0.109
0.0GlnHis: 0.0 ± 0.0
3.797GlnIle: 3.797 ± 1.301
2.532GlnLys: 2.532 ± 1.298
2.532GlnLeu: 2.532 ± 0.868
1.266GlnMet: 1.266 ± 0.241
0.633GlnAsn: 0.633 ± 0.324
2.532GlnPro: 2.532 ± 0.868
1.899GlnGln: 1.899 ± 2.275
3.165GlnArg: 3.165 ± 0.543
3.165GlnSer: 3.165 ± 1.622
0.633GlnThr: 0.633 ± 0.324
3.165GlnVal: 3.165 ± 1.626
1.266GlnTrp: 1.266 ± 0.434
1.899GlnTyr: 1.899 ± 0.109
0.0GlnXaa: 0.0 ± 0.0
Arg
5.063ArgAla: 5.063 ± 1.513
0.0ArgCys: 0.0 ± 0.0
3.165ArgAsp: 3.165 ± 1.622
1.266ArgGlu: 1.266 ± 0.434
2.532ArgPhe: 2.532 ± 0.215
1.899ArgGly: 1.899 ± 0.109
1.266ArgHis: 1.266 ± 0.649
1.266ArgIle: 1.266 ± 0.649
3.165ArgLys: 3.165 ± 1.622
2.532ArgLeu: 2.532 ± 1.298
1.266ArgMet: 1.266 ± 1.517
5.063ArgAsn: 5.063 ± 2.596
1.266ArgPro: 1.266 ± 0.649
2.532ArgGln: 2.532 ± 0.215
1.266ArgArg: 1.266 ± 0.649
3.165ArgSer: 3.165 ± 1.626
4.43ArgThr: 4.43 ± 2.06
3.797ArgVal: 3.797 ± 0.864
0.0ArgTrp: 0.0 ± 0.0
1.899ArgTyr: 1.899 ± 0.109
0.0ArgXaa: 0.0 ± 0.0
Ser
6.329SerAla: 6.329 ± 0.003
1.899SerCys: 1.899 ± 0.973
3.165SerAsp: 3.165 ± 1.626
0.0SerGlu: 0.0 ± 0.0
1.899SerPhe: 1.899 ± 1.192
7.595SerGly: 7.595 ± 0.646
1.899SerHis: 1.899 ± 0.973
5.063SerIle: 5.063 ± 4.984
2.532SerLys: 2.532 ± 1.298
5.696SerLeu: 5.696 ± 0.328
0.0SerMet: 0.0 ± 0.0
5.063SerAsn: 5.063 ± 0.652
6.329SerPro: 6.329 ± 0.003
3.165SerGln: 3.165 ± 1.626
4.43SerArg: 4.43 ± 1.189
5.696SerSer: 5.696 ± 0.328
8.228SerThr: 8.228 ± 1.196
3.797SerVal: 3.797 ± 2.384
0.633SerTrp: 0.633 ± 0.758
3.165SerTyr: 3.165 ± 1.626
0.0SerXaa: 0.0 ± 0.0
Thr
4.43ThrAla: 4.43 ± 1.189
1.899ThrCys: 1.899 ± 1.192
4.43ThrAsp: 4.43 ± 1.189
1.899ThrGlu: 1.899 ± 0.973
3.797ThrPhe: 3.797 ± 0.219
7.595ThrGly: 7.595 ± 3.686
1.266ThrHis: 1.266 ± 0.649
3.797ThrIle: 3.797 ± 0.219
6.329ThrLys: 6.329 ± 2.169
4.43ThrLeu: 4.43 ± 0.977
0.633ThrMet: 0.633 ± 0.324
3.797ThrAsn: 3.797 ± 0.219
1.899ThrPro: 1.899 ± 1.192
5.063ThrGln: 5.063 ± 0.43
3.165ThrArg: 3.165 ± 0.54
7.595ThrSer: 7.595 ± 0.646
10.127ThrThr: 10.127 ± 4.553
9.494ThrVal: 9.494 ± 3.795
0.0ThrTrp: 0.0 ± 0.0
3.797ThrTyr: 3.797 ± 1.301
0.0ThrXaa: 0.0 ± 0.0
Val
6.962ValAla: 6.962 ± 2.927
0.633ValCys: 0.633 ± 0.324
3.797ValAsp: 3.797 ± 0.864
2.532ValGlu: 2.532 ± 1.298
3.797ValPhe: 3.797 ± 0.219
4.43ValGly: 4.43 ± 2.06
1.899ValHis: 1.899 ± 0.973
3.797ValIle: 3.797 ± 0.219
8.228ValLys: 8.228 ± 0.97
7.595ValLeu: 7.595 ± 0.437
4.43ValMet: 4.43 ± 1.189
1.266ValAsn: 1.266 ± 0.434
4.43ValPro: 4.43 ± 2.06
2.532ValGln: 2.532 ± 1.95
2.532ValArg: 2.532 ± 1.298
1.899ValSer: 1.899 ± 0.973
4.43ValThr: 4.43 ± 0.977
3.797ValVal: 3.797 ± 1.947
0.633ValTrp: 0.633 ± 0.324
0.633ValTyr: 0.633 ± 0.758
0.0ValXaa: 0.0 ± 0.0
Trp
0.633TrpAla: 0.633 ± 0.324
0.0TrpCys: 0.0 ± 0.0
0.633TrpAsp: 0.633 ± 0.324
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.633TrpGly: 0.633 ± 0.324
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.633TrpLys: 0.633 ± 0.758
0.633TrpLeu: 0.633 ± 0.324
0.633TrpMet: 0.633 ± 0.324
1.899TrpAsn: 1.899 ± 0.109
1.266TrpPro: 1.266 ± 0.649
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.266TrpSer: 1.266 ± 1.517
0.0TrpThr: 0.0 ± 0.0
0.633TrpVal: 0.633 ± 0.324
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.797TyrAla: 3.797 ± 2.384
1.266TyrCys: 1.266 ± 0.434
1.899TyrAsp: 1.899 ± 0.973
2.532TyrGlu: 2.532 ± 0.868
1.266TyrPhe: 1.266 ± 0.434
5.063TyrGly: 5.063 ± 0.652
1.266TyrHis: 1.266 ± 1.517
2.532TyrIle: 2.532 ± 1.95
2.532TyrLys: 2.532 ± 1.298
1.899TyrLeu: 1.899 ± 0.973
1.266TyrMet: 1.266 ± 0.434
2.532TyrAsn: 2.532 ± 1.298
0.0TyrPro: 0.0 ± 0.0
0.633TyrGln: 0.633 ± 0.758
1.266TyrArg: 1.266 ± 0.649
1.899TyrSer: 1.899 ± 0.109
3.797TyrThr: 3.797 ± 0.219
3.797TyrVal: 3.797 ± 0.864
0.633TyrTrp: 0.633 ± 0.324
2.532TyrTyr: 2.532 ± 1.298
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1581 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski