Amino acid dipepetide frequency for CRESS virus sp. ct6pe1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.246AlaAla: 7.246 ± 2.199
0.0AlaCys: 0.0 ± 0.0
4.348AlaAsp: 4.348 ± 3.388
1.449AlaGlu: 1.449 ± 1.028
2.899AlaPhe: 2.899 ± 3.444
5.797AlaGly: 5.797 ± 4.113
4.348AlaHis: 4.348 ± 3.388
5.797AlaIle: 5.797 ± 4.113
0.0AlaLys: 0.0 ± 0.0
4.348AlaLeu: 4.348 ± 1.571
2.899AlaMet: 2.899 ± 2.351
0.0AlaAsn: 0.0 ± 0.0
4.348AlaPro: 4.348 ± 3.388
2.899AlaGln: 2.899 ± 0.698
10.145AlaArg: 10.145 ± 2.5
4.348AlaSer: 4.348 ± 3.084
4.348AlaThr: 4.348 ± 1.347
1.449AlaVal: 1.449 ± 1.028
1.449AlaTrp: 1.449 ± 1.028
1.449AlaTyr: 1.449 ± 1.129
0.0AlaXaa: 0.0 ± 0.0
Cys
1.449CysAla: 1.449 ± 3.585
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
2.899CysPhe: 2.899 ± 2.258
0.0CysGly: 0.0 ± 0.0
1.449CysHis: 1.449 ± 1.028
0.0CysIle: 0.0 ± 0.0
1.449CysLys: 1.449 ± 1.129
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
7.246AspAsp: 7.246 ± 2.153
1.449AspGlu: 1.449 ± 1.129
1.449AspPhe: 1.449 ± 1.129
2.899AspGly: 2.899 ± 0.698
0.0AspHis: 0.0 ± 0.0
2.899AspIle: 2.899 ± 0.698
0.0AspLys: 0.0 ± 0.0
7.246AspLeu: 7.246 ± 3.288
1.449AspMet: 1.449 ± 1.835
5.797AspAsn: 5.797 ± 1.396
2.899AspPro: 2.899 ± 2.056
5.797AspGln: 5.797 ± 1.396
7.246AspArg: 7.246 ± 4.638
1.449AspSer: 1.449 ± 1.129
4.348AspThr: 4.348 ± 1.347
5.797AspVal: 5.797 ± 2.646
0.0AspTrp: 0.0 ± 0.0
1.449AspTyr: 1.449 ± 1.028
0.0AspXaa: 0.0 ± 0.0
Glu
4.348GluAla: 4.348 ± 3.084
0.0GluCys: 0.0 ± 0.0
5.797GluAsp: 5.797 ± 2.646
2.899GluGlu: 2.899 ± 2.258
4.348GluPhe: 4.348 ± 3.388
7.246GluGly: 7.246 ± 1.883
4.348GluHis: 4.348 ± 3.388
1.449GluIle: 1.449 ± 3.585
0.0GluLys: 0.0 ± 0.0
1.449GluLeu: 1.449 ± 1.129
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
1.449GluGln: 1.449 ± 1.129
1.449GluArg: 1.449 ± 1.129
5.797GluSer: 5.797 ± 1.396
1.449GluThr: 1.449 ± 1.028
1.449GluVal: 1.449 ± 1.129
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.899PheAla: 2.899 ± 2.056
1.449PheCys: 1.449 ± 1.129
0.0PheAsp: 0.0 ± 0.0
1.449PheGlu: 1.449 ± 1.028
4.348PhePhe: 4.348 ± 1.571
2.899PheGly: 2.899 ± 0.698
1.449PheHis: 1.449 ± 1.129
4.348PheIle: 4.348 ± 2.891
4.348PheLys: 4.348 ± 1.347
2.899PheLeu: 2.899 ± 2.258
0.0PheMet: 0.0 ± 0.0
2.899PheAsn: 2.899 ± 0.698
0.0PhePro: 0.0 ± 0.0
1.449PheGln: 1.449 ± 1.129
1.449PheArg: 1.449 ± 1.028
5.797PheSer: 5.797 ± 2.646
4.348PheThr: 4.348 ± 2.891
2.899PheVal: 2.899 ± 0.698
0.0PheTrp: 0.0 ± 0.0
1.449PheTyr: 1.449 ± 1.028
0.0PheXaa: 0.0 ± 0.0
Gly
10.145GlyAla: 10.145 ± 3.616
0.0GlyCys: 0.0 ± 0.0
4.348GlyAsp: 4.348 ± 1.347
1.449GlyGlu: 1.449 ± 1.028
1.449GlyPhe: 1.449 ± 1.129
4.348GlyGly: 4.348 ± 1.347
0.0GlyHis: 0.0 ± 0.0
5.797GlyIle: 5.797 ± 4.113
7.246GlyLys: 7.246 ± 3.752
1.449GlyLeu: 1.449 ± 1.028
2.899GlyMet: 2.899 ± 3.444
1.449GlyAsn: 1.449 ± 1.028
2.899GlyPro: 2.899 ± 3.444
4.348GlyGln: 4.348 ± 3.084
2.899GlyArg: 2.899 ± 2.258
2.899GlySer: 2.899 ± 3.444
8.696GlyThr: 8.696 ± 2.094
2.899GlyVal: 2.899 ± 2.056
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.449HisGlu: 1.449 ± 1.129
1.449HisPhe: 1.449 ± 1.028
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
7.246HisIle: 7.246 ± 3.752
0.0HisLys: 0.0 ± 0.0
2.899HisLeu: 2.899 ± 2.258
1.449HisMet: 1.449 ± 1.129
2.899HisAsn: 2.899 ± 2.056
2.899HisPro: 2.899 ± 2.258
1.449HisGln: 1.449 ± 1.028
2.899HisArg: 2.899 ± 0.698
1.449HisSer: 1.449 ± 3.585
1.449HisThr: 1.449 ± 1.129
2.899HisVal: 2.899 ± 0.698
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.348IleAla: 4.348 ± 3.084
1.449IleCys: 1.449 ± 1.129
4.348IleAsp: 4.348 ± 1.347
5.797IleGlu: 5.797 ± 1.396
4.348IlePhe: 4.348 ± 2.891
2.899IleGly: 2.899 ± 0.698
4.348IleHis: 4.348 ± 1.347
1.449IleIle: 1.449 ± 1.028
0.0IleLys: 0.0 ± 0.0
4.348IleLeu: 4.348 ± 1.571
1.449IleMet: 1.449 ± 1.028
2.899IleAsn: 2.899 ± 0.698
2.899IlePro: 2.899 ± 3.345
1.449IleGln: 1.449 ± 1.129
4.348IleArg: 4.348 ± 3.084
4.348IleSer: 4.348 ± 6.954
5.797IleThr: 5.797 ± 1.396
2.899IleVal: 2.899 ± 0.698
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.449LysAla: 1.449 ± 1.129
0.0LysCys: 0.0 ± 0.0
4.348LysAsp: 4.348 ± 1.571
1.449LysGlu: 1.449 ± 1.028
2.899LysPhe: 2.899 ± 2.056
1.449LysGly: 1.449 ± 1.129
1.449LysHis: 1.449 ± 1.028
1.449LysIle: 1.449 ± 1.028
5.797LysLys: 5.797 ± 2.292
1.449LysLeu: 1.449 ± 1.028
2.899LysMet: 2.899 ± 2.258
0.0LysAsn: 0.0 ± 0.0
0.0LysPro: 0.0 ± 0.0
0.0LysGln: 0.0 ± 0.0
7.246LysArg: 7.246 ± 3.288
4.348LysSer: 4.348 ± 1.571
7.246LysThr: 7.246 ± 3.0
4.348LysVal: 4.348 ± 1.347
1.449LysTrp: 1.449 ± 1.129
4.348LysTyr: 4.348 ± 1.571
0.0LysXaa: 0.0 ± 0.0
Leu
4.348LeuAla: 4.348 ± 1.571
0.0LeuCys: 0.0 ± 0.0
5.797LeuAsp: 5.797 ± 1.396
8.696LeuGlu: 8.696 ± 6.775
0.0LeuPhe: 0.0 ± 0.0
0.0LeuGly: 0.0 ± 0.0
0.0LeuHis: 0.0 ± 0.0
2.899LeuIle: 2.899 ± 0.698
4.348LeuLys: 4.348 ± 1.347
0.0LeuLeu: 0.0 ± 0.0
1.449LeuMet: 1.449 ± 1.129
4.348LeuAsn: 4.348 ± 1.571
1.449LeuPro: 1.449 ± 1.028
2.899LeuGln: 2.899 ± 2.258
4.348LeuArg: 4.348 ± 6.954
1.449LeuSer: 1.449 ± 1.129
7.246LeuThr: 7.246 ± 3.0
8.696LeuVal: 8.696 ± 2.093
0.0LeuTrp: 0.0 ± 0.0
4.348LeuTyr: 4.348 ± 1.347
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.449MetGlu: 1.449 ± 1.129
1.449MetPhe: 1.449 ± 1.028
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.899MetIle: 2.899 ± 3.444
4.348MetLys: 4.348 ± 1.347
4.348MetLeu: 4.348 ± 1.571
1.449MetMet: 1.449 ± 1.028
2.899MetAsn: 2.899 ± 2.258
2.899MetPro: 2.899 ± 0.698
0.0MetGln: 0.0 ± 0.0
2.899MetArg: 2.899 ± 2.056
2.899MetSer: 2.899 ± 0.698
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
2.899MetTyr: 2.899 ± 7.17
0.0MetXaa: 0.0 ± 0.0
Asn
1.449AsnAla: 1.449 ± 1.129
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
4.348AsnGlu: 4.348 ± 1.571
0.0AsnPhe: 0.0 ± 0.0
2.899AsnGly: 2.899 ± 0.698
1.449AsnHis: 1.449 ± 1.129
0.0AsnIle: 0.0 ± 0.0
4.348AsnLys: 4.348 ± 1.347
1.449AsnLeu: 1.449 ± 1.028
1.449AsnMet: 1.449 ± 1.028
1.449AsnAsn: 1.449 ± 1.129
1.449AsnPro: 1.449 ± 1.129
2.899AsnGln: 2.899 ± 2.056
0.0AsnArg: 0.0 ± 0.0
4.348AsnSer: 4.348 ± 3.603
2.899AsnThr: 2.899 ± 3.444
5.797AsnVal: 5.797 ± 2.646
1.449AsnTrp: 1.449 ± 1.028
4.348AsnTyr: 4.348 ± 1.571
0.0AsnXaa: 0.0 ± 0.0
Pro
4.348ProAla: 4.348 ± 1.571
0.0ProCys: 0.0 ± 0.0
5.797ProAsp: 5.797 ± 2.646
1.449ProGlu: 1.449 ± 1.129
1.449ProPhe: 1.449 ± 1.028
1.449ProGly: 1.449 ± 1.129
1.449ProHis: 1.449 ± 1.129
1.449ProIle: 1.449 ± 1.028
4.348ProLys: 4.348 ± 3.476
1.449ProLeu: 1.449 ± 3.585
1.449ProMet: 1.449 ± 0.883
0.0ProAsn: 0.0 ± 0.0
2.899ProPro: 2.899 ± 2.258
1.449ProGln: 1.449 ± 1.129
2.899ProArg: 2.899 ± 0.698
4.348ProSer: 4.348 ± 2.891
4.348ProThr: 4.348 ± 1.347
2.899ProVal: 2.899 ± 2.258
1.449ProTrp: 1.449 ± 1.129
1.449ProTyr: 1.449 ± 1.028
0.0ProXaa: 0.0 ± 0.0
Gln
7.246GlnAla: 7.246 ± 1.883
0.0GlnCys: 0.0 ± 0.0
1.449GlnAsp: 1.449 ± 1.028
0.0GlnGlu: 0.0 ± 0.0
2.899GlnPhe: 2.899 ± 0.698
2.899GlnGly: 2.899 ± 0.698
1.449GlnHis: 1.449 ± 1.028
0.0GlnIle: 0.0 ± 0.0
4.348GlnLys: 4.348 ± 1.347
2.899GlnLeu: 2.899 ± 2.258
2.899GlnMet: 2.899 ± 2.258
0.0GlnAsn: 0.0 ± 0.0
1.449GlnPro: 1.449 ± 1.129
0.0GlnGln: 0.0 ± 0.0
1.449GlnArg: 1.449 ± 1.129
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
2.899GlnVal: 2.899 ± 2.056
0.0GlnTrp: 0.0 ± 0.0
2.899GlnTyr: 2.899 ± 0.698
0.0GlnXaa: 0.0 ± 0.0
Arg
5.797ArgAla: 5.797 ± 2.763
2.899ArgCys: 2.899 ± 3.444
7.246ArgAsp: 7.246 ± 2.199
1.449ArgGlu: 1.449 ± 1.129
4.348ArgPhe: 4.348 ± 1.347
7.246ArgGly: 7.246 ± 3.004
7.246ArgHis: 7.246 ± 2.199
2.899ArgIle: 2.899 ± 2.258
2.899ArgLys: 2.899 ± 0.698
1.449ArgLeu: 1.449 ± 1.028
5.797ArgMet: 5.797 ± 4.027
5.797ArgAsn: 5.797 ± 2.763
4.348ArgPro: 4.348 ± 1.347
0.0ArgGln: 0.0 ± 0.0
14.493ArgArg: 14.493 ± 4.869
2.899ArgSer: 2.899 ± 2.056
4.348ArgThr: 4.348 ± 1.571
5.797ArgVal: 5.797 ± 2.292
0.0ArgTrp: 0.0 ± 0.0
1.449ArgTyr: 1.449 ± 1.129
0.0ArgXaa: 0.0 ± 0.0
Ser
4.348SerAla: 4.348 ± 1.571
0.0SerCys: 0.0 ± 0.0
2.899SerAsp: 2.899 ± 0.698
2.899SerGlu: 2.899 ± 3.444
0.0SerPhe: 0.0 ± 0.0
8.696SerGly: 8.696 ± 2.093
0.0SerHis: 0.0 ± 0.0
2.899SerIle: 2.899 ± 2.258
4.348SerLys: 4.348 ± 1.347
5.797SerLeu: 5.797 ± 6.691
0.0SerMet: 0.0 ± 0.0
4.348SerAsn: 4.348 ± 2.891
2.899SerPro: 2.899 ± 0.698
0.0SerGln: 0.0 ± 0.0
8.696SerArg: 8.696 ± 2.093
4.348SerSer: 4.348 ± 3.603
2.899SerThr: 2.899 ± 2.056
2.899SerVal: 2.899 ± 7.17
4.348SerTrp: 4.348 ± 1.347
1.449SerTyr: 1.449 ± 1.028
0.0SerXaa: 0.0 ± 0.0
Thr
4.348ThrAla: 4.348 ± 1.347
0.0ThrCys: 0.0 ± 0.0
1.449ThrAsp: 1.449 ± 1.129
4.348ThrGlu: 4.348 ± 1.347
1.449ThrPhe: 1.449 ± 1.129
4.348ThrGly: 4.348 ± 3.603
0.0ThrHis: 0.0 ± 0.0
7.246ThrIle: 7.246 ± 1.883
1.449ThrLys: 1.449 ± 1.129
2.899ThrLeu: 2.899 ± 3.345
0.0ThrMet: 0.0 ± 0.0
5.797ThrAsn: 5.797 ± 1.396
5.797ThrPro: 5.797 ± 2.646
1.449ThrGln: 1.449 ± 1.129
10.145ThrArg: 10.145 ± 6.321
7.246ThrSer: 7.246 ± 2.199
10.145ThrThr: 10.145 ± 6.214
7.246ThrVal: 7.246 ± 2.153
2.899ThrTrp: 2.899 ± 2.056
2.899ThrTyr: 2.899 ± 2.258
0.0ThrXaa: 0.0 ± 0.0
Val
4.348ValAla: 4.348 ± 1.571
0.0ValCys: 0.0 ± 0.0
2.899ValAsp: 2.899 ± 0.698
1.449ValGlu: 1.449 ± 1.129
2.899ValPhe: 2.899 ± 2.258
4.348ValGly: 4.348 ± 1.347
0.0ValHis: 0.0 ± 0.0
4.348ValIle: 4.348 ± 1.571
2.899ValLys: 2.899 ± 0.698
10.145ValLeu: 10.145 ± 2.789
1.449ValMet: 1.449 ± 1.028
1.449ValAsn: 1.449 ± 1.028
5.797ValPro: 5.797 ± 2.721
5.797ValGln: 5.797 ± 2.292
4.348ValArg: 4.348 ± 3.603
1.449ValSer: 1.449 ± 1.129
4.348ValThr: 4.348 ± 2.891
4.348ValVal: 4.348 ± 3.476
2.899ValTrp: 2.899 ± 2.056
1.449ValTyr: 1.449 ± 3.585
0.0ValXaa: 0.0 ± 0.0
Trp
1.449TrpAla: 1.449 ± 1.129
0.0TrpCys: 0.0 ± 0.0
1.449TrpAsp: 1.449 ± 1.028
0.0TrpGlu: 0.0 ± 0.0
2.899TrpPhe: 2.899 ± 0.698
2.899TrpGly: 2.899 ± 2.056
0.0TrpHis: 0.0 ± 0.0
1.449TrpIle: 1.449 ± 1.028
0.0TrpLys: 0.0 ± 0.0
1.449TrpLeu: 1.449 ± 1.028
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.449TrpGln: 1.449 ± 1.129
0.0TrpArg: 0.0 ± 0.0
1.449TrpSer: 1.449 ± 1.028
1.449TrpThr: 1.449 ± 1.028
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.449TyrCys: 1.449 ± 1.129
1.449TyrAsp: 1.449 ± 1.028
0.0TyrGlu: 0.0 ± 0.0
2.899TyrPhe: 2.899 ± 2.056
2.899TyrGly: 2.899 ± 2.056
1.449TyrHis: 1.449 ± 1.129
2.899TyrIle: 2.899 ± 3.444
1.449TyrLys: 1.449 ± 1.028
4.348TyrLeu: 4.348 ± 3.388
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
1.449TyrPro: 1.449 ± 1.129
0.0TyrGln: 0.0 ± 0.0
1.449TyrArg: 1.449 ± 1.028
2.899TyrSer: 2.899 ± 3.345
5.797TyrThr: 5.797 ± 2.646
1.449TyrVal: 1.449 ± 3.585
0.0TyrTrp: 0.0 ± 0.0
1.449TyrTyr: 1.449 ± 3.585
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (691 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski