Amino acid dipepetide frequency for Blueberry virus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.918AlaAla: 5.918 ± 0.657
1.16AlaCys: 1.16 ± 0.308
2.553AlaAsp: 2.553 ± 0.35
3.713AlaGlu: 3.713 ± 0.588
3.713AlaPhe: 3.713 ± 0.644
3.365AlaGly: 3.365 ± 0.664
1.392AlaHis: 1.392 ± 0.37
2.321AlaIle: 2.321 ± 0.18
3.249AlaLys: 3.249 ± 0.868
7.89AlaLeu: 7.89 ± 0.704
2.205AlaMet: 2.205 ± 0.338
2.205AlaAsn: 2.205 ± 0.7
2.901AlaPro: 2.901 ± 0.477
1.741AlaGln: 1.741 ± 0.32
3.713AlaArg: 3.713 ± 0.512
6.382AlaSer: 6.382 ± 0.603
4.757AlaThr: 4.757 ± 0.727
6.15AlaVal: 6.15 ± 0.756
0.464AlaTrp: 0.464 ± 0.123
3.249AlaTyr: 3.249 ± 0.461
0.0AlaXaa: 0.0 ± 0.0
Cys
2.205CysAla: 2.205 ± 0.352
0.116CysCys: 0.116 ± 0.171
3.133CysAsp: 3.133 ± 0.455
0.464CysGlu: 0.464 ± 0.214
0.348CysPhe: 0.348 ± 0.112
1.508CysGly: 1.508 ± 0.292
0.348CysHis: 0.348 ± 0.139
0.58CysIle: 0.58 ± 0.163
1.16CysLys: 1.16 ± 0.262
1.276CysLeu: 1.276 ± 0.674
0.464CysMet: 0.464 ± 0.183
1.276CysAsn: 1.276 ± 0.312
0.812CysPro: 0.812 ± 0.22
0.696CysGln: 0.696 ± 0.201
1.625CysArg: 1.625 ± 0.321
2.205CysSer: 2.205 ± 0.275
1.276CysThr: 1.276 ± 0.142
1.741CysVal: 1.741 ± 0.224
0.464CysTrp: 0.464 ± 0.123
0.812CysTyr: 0.812 ± 0.154
0.0CysXaa: 0.0 ± 0.0
Asp
3.829AspAla: 3.829 ± 0.595
1.973AspCys: 1.973 ± 0.275
5.222AspAsp: 5.222 ± 0.363
3.597AspGlu: 3.597 ± 0.452
3.597AspPhe: 3.597 ± 0.32
2.205AspGly: 2.205 ± 0.277
1.741AspHis: 1.741 ± 0.216
3.713AspIle: 3.713 ± 0.429
1.857AspLys: 1.857 ± 0.285
6.266AspLeu: 6.266 ± 0.361
1.625AspMet: 1.625 ± 0.203
2.437AspAsn: 2.437 ± 0.688
1.276AspPro: 1.276 ± 0.284
0.58AspGln: 0.58 ± 0.134
3.481AspArg: 3.481 ± 0.294
7.078AspSer: 7.078 ± 0.53
1.857AspThr: 1.857 ± 0.342
5.57AspVal: 5.57 ± 0.303
0.464AspTrp: 0.464 ± 0.236
1.973AspTyr: 1.973 ± 0.391
0.0AspXaa: 0.0 ± 0.0
Glu
2.205GluAla: 2.205 ± 0.406
1.16GluCys: 1.16 ± 0.431
2.437GluAsp: 2.437 ± 0.737
3.597GluGlu: 3.597 ± 0.536
2.669GluPhe: 2.669 ± 0.423
1.857GluGly: 1.857 ± 0.289
0.58GluHis: 0.58 ± 0.134
3.829GluIle: 3.829 ± 0.737
3.597GluLys: 3.597 ± 0.403
4.177GluLeu: 4.177 ± 0.53
1.392GluMet: 1.392 ± 0.877
2.321GluAsn: 2.321 ± 0.602
1.973GluPro: 1.973 ± 0.271
0.348GluGln: 0.348 ± 0.317
2.321GluArg: 2.321 ± 0.385
4.177GluSer: 4.177 ± 0.605
2.205GluThr: 2.205 ± 0.51
4.409GluVal: 4.409 ± 1.033
1.16GluTrp: 1.16 ± 0.268
1.741GluTyr: 1.741 ± 0.233
0.0GluXaa: 0.0 ± 0.0
Phe
1.973PheAla: 1.973 ± 0.275
0.928PheCys: 0.928 ± 0.273
3.713PheAsp: 3.713 ± 0.584
2.205PheGlu: 2.205 ± 0.814
3.365PhePhe: 3.365 ± 0.429
3.133PheGly: 3.133 ± 0.293
1.392PheHis: 1.392 ± 0.464
3.829PheIle: 3.829 ± 0.392
1.741PheLys: 1.741 ± 0.343
5.338PheLeu: 5.338 ± 0.521
1.508PheMet: 1.508 ± 0.396
2.089PheAsn: 2.089 ± 0.707
1.044PhePro: 1.044 ± 0.193
0.696PheGln: 0.696 ± 0.215
2.321PheArg: 2.321 ± 0.37
4.061PheSer: 4.061 ± 0.565
3.249PheThr: 3.249 ± 0.469
3.945PheVal: 3.945 ± 0.598
0.464PheTrp: 0.464 ± 0.123
1.857PheTyr: 1.857 ± 0.347
0.0PheXaa: 0.0 ± 0.0
Gly
3.017GlyAla: 3.017 ± 0.353
1.044GlyCys: 1.044 ± 0.516
6.73GlyAsp: 6.73 ± 0.652
3.829GlyGlu: 3.829 ± 0.52
1.857GlyPhe: 1.857 ± 0.346
6.382GlyGly: 6.382 ± 0.669
1.044GlyHis: 1.044 ± 0.238
2.321GlyIle: 2.321 ± 0.196
1.973GlyLys: 1.973 ± 0.217
4.293GlyLeu: 4.293 ± 0.323
0.928GlyMet: 0.928 ± 0.139
1.857GlyAsn: 1.857 ± 0.252
1.044GlyPro: 1.044 ± 0.193
0.232GlyGln: 0.232 ± 0.062
3.713GlyArg: 3.713 ± 0.497
6.498GlySer: 6.498 ± 0.652
2.437GlyThr: 2.437 ± 0.286
5.454GlyVal: 5.454 ± 0.588
0.696GlyTrp: 0.696 ± 0.177
2.553GlyTyr: 2.553 ± 0.401
0.0GlyXaa: 0.0 ± 0.0
His
1.16HisAla: 1.16 ± 0.308
1.276HisCys: 1.276 ± 0.402
0.812HisAsp: 0.812 ± 0.246
0.696HisGlu: 0.696 ± 0.215
1.625HisPhe: 1.625 ± 0.222
1.741HisGly: 1.741 ± 0.393
0.696HisHis: 0.696 ± 0.185
0.928HisIle: 0.928 ± 0.247
0.464HisLys: 0.464 ± 0.123
2.321HisLeu: 2.321 ± 0.362
0.116HisMet: 0.116 ± 0.078
1.044HisAsn: 1.044 ± 0.195
0.464HisPro: 0.464 ± 0.123
0.348HisGln: 0.348 ± 0.156
0.58HisArg: 0.58 ± 0.146
2.089HisSer: 2.089 ± 0.387
1.392HisThr: 1.392 ± 0.413
2.089HisVal: 2.089 ± 0.264
0.232HisTrp: 0.232 ± 0.062
1.16HisTyr: 1.16 ± 0.301
0.0HisXaa: 0.0 ± 0.0
Ile
2.321IleAla: 2.321 ± 0.443
2.089IleCys: 2.089 ± 0.281
2.785IleAsp: 2.785 ± 0.153
2.553IleGlu: 2.553 ± 0.372
2.321IlePhe: 2.321 ± 0.362
2.785IleGly: 2.785 ± 0.372
0.696IleHis: 0.696 ± 0.141
2.553IleIle: 2.553 ± 0.415
3.713IleLys: 3.713 ± 0.528
4.757IleLeu: 4.757 ± 0.308
0.812IleMet: 0.812 ± 0.453
3.945IleAsn: 3.945 ± 0.425
1.741IlePro: 1.741 ± 0.259
1.276IleGln: 1.276 ± 0.244
4.641IleArg: 4.641 ± 0.556
4.874IleSer: 4.874 ± 0.478
2.785IleThr: 2.785 ± 1.113
2.437IleVal: 2.437 ± 0.508
0.232IleTrp: 0.232 ± 0.205
2.205IleTyr: 2.205 ± 0.29
0.0IleXaa: 0.0 ± 0.0
Lys
5.57LysAla: 5.57 ± 0.622
1.276LysCys: 1.276 ± 0.208
4.177LysAsp: 4.177 ± 0.515
2.785LysGlu: 2.785 ± 0.907
2.669LysPhe: 2.669 ± 0.621
1.508LysGly: 1.508 ± 0.41
1.044LysHis: 1.044 ± 0.226
1.392LysIle: 1.392 ± 0.276
2.669LysLys: 2.669 ± 0.795
6.846LysLeu: 6.846 ± 0.522
1.741LysMet: 1.741 ± 0.666
2.901LysAsn: 2.901 ± 0.74
1.16LysPro: 1.16 ± 0.262
0.928LysGln: 0.928 ± 0.265
3.017LysArg: 3.017 ± 0.481
4.061LysSer: 4.061 ± 0.73
2.437LysThr: 2.437 ± 0.485
5.222LysVal: 5.222 ± 0.935
0.812LysTrp: 0.812 ± 0.156
2.205LysTyr: 2.205 ± 0.615
0.0LysXaa: 0.0 ± 0.0
Leu
4.874LeuAla: 4.874 ± 0.737
3.249LeuCys: 3.249 ± 0.655
4.409LeuAsp: 4.409 ± 0.312
5.222LeuGlu: 5.222 ± 1.03
4.177LeuPhe: 4.177 ± 1.104
5.338LeuGly: 5.338 ± 0.389
1.625LeuHis: 1.625 ± 0.271
5.338LeuIle: 5.338 ± 0.259
6.034LeuLys: 6.034 ± 1.142
7.194LeuLeu: 7.194 ± 1.05
1.625LeuMet: 1.625 ± 0.463
5.106LeuAsn: 5.106 ± 0.87
3.829LeuPro: 3.829 ± 0.564
2.089LeuGln: 2.089 ± 0.575
4.99LeuArg: 4.99 ± 0.862
7.89LeuSer: 7.89 ± 0.658
6.266LeuThr: 6.266 ± 0.544
7.426LeuVal: 7.426 ± 0.817
0.696LeuTrp: 0.696 ± 0.203
2.553LeuTyr: 2.553 ± 0.394
0.0LeuXaa: 0.0 ± 0.0
Met
1.276MetAla: 1.276 ± 0.403
0.348MetCys: 0.348 ± 0.139
0.812MetAsp: 0.812 ± 0.294
1.16MetGlu: 1.16 ± 0.227
0.232MetPhe: 0.232 ± 0.338
1.044MetGly: 1.044 ± 0.147
0.464MetHis: 0.464 ± 0.532
1.857MetIle: 1.857 ± 0.312
1.508MetLys: 1.508 ± 0.39
2.437MetLeu: 2.437 ± 0.347
0.0MetMet: 0.0 ± 0.0
1.276MetAsn: 1.276 ± 0.477
0.58MetPro: 0.58 ± 0.134
0.232MetGln: 0.232 ± 0.332
1.508MetArg: 1.508 ± 0.2
2.901MetSer: 2.901 ± 0.342
1.741MetThr: 1.741 ± 0.581
2.089MetVal: 2.089 ± 0.459
0.0MetTrp: 0.0 ± 0.0
1.392MetTyr: 1.392 ± 0.371
0.0MetXaa: 0.0 ± 0.0
Asn
3.481AsnAla: 3.481 ± 0.826
1.392AsnCys: 1.392 ± 0.261
1.508AsnAsp: 1.508 ± 0.405
1.857AsnGlu: 1.857 ± 0.395
2.553AsnPhe: 2.553 ± 0.622
2.321AsnGly: 2.321 ± 0.394
0.58AsnHis: 0.58 ± 0.189
3.249AsnIle: 3.249 ± 0.265
2.553AsnLys: 2.553 ± 0.296
4.293AsnLeu: 4.293 ± 0.816
0.348AsnMet: 0.348 ± 0.139
1.857AsnAsn: 1.857 ± 0.338
2.089AsnPro: 2.089 ± 0.314
1.044AsnGln: 1.044 ± 0.193
3.945AsnArg: 3.945 ± 0.447
3.713AsnSer: 3.713 ± 0.395
1.973AsnThr: 1.973 ± 0.463
3.829AsnVal: 3.829 ± 0.991
0.696AsnTrp: 0.696 ± 0.27
1.508AsnTyr: 1.508 ± 0.323
0.0AsnXaa: 0.0 ± 0.0
Pro
3.597ProAla: 3.597 ± 0.706
0.232ProCys: 0.232 ± 0.245
1.741ProAsp: 1.741 ± 0.561
1.392ProGlu: 1.392 ± 0.249
1.973ProPhe: 1.973 ± 0.28
2.669ProGly: 2.669 ± 0.689
0.58ProHis: 0.58 ± 0.134
1.508ProIle: 1.508 ± 0.189
1.625ProLys: 1.625 ± 0.207
2.089ProLeu: 2.089 ± 0.623
0.928ProMet: 0.928 ± 0.396
1.625ProAsn: 1.625 ± 0.203
3.481ProPro: 3.481 ± 0.671
0.116ProGln: 0.116 ± 0.127
2.321ProArg: 2.321 ± 0.494
5.918ProSer: 5.918 ± 1.247
3.133ProThr: 3.133 ± 0.49
2.321ProVal: 2.321 ± 0.283
0.232ProTrp: 0.232 ± 0.062
0.696ProTyr: 0.696 ± 0.234
0.0ProXaa: 0.0 ± 0.0
Gln
1.276GlnAla: 1.276 ± 0.301
0.464GlnCys: 0.464 ± 0.123
0.58GlnAsp: 0.58 ± 0.194
0.464GlnGlu: 0.464 ± 0.147
1.857GlnPhe: 1.857 ± 0.265
1.625GlnGly: 1.625 ± 0.295
1.044GlnHis: 1.044 ± 0.177
2.089GlnIle: 2.089 ± 0.273
0.232GlnLys: 0.232 ± 0.247
2.437GlnLeu: 2.437 ± 0.379
0.348GlnMet: 0.348 ± 0.112
0.464GlnAsn: 0.464 ± 0.144
0.464GlnPro: 0.464 ± 0.123
0.232GlnGln: 0.232 ± 0.062
1.857GlnArg: 1.857 ± 0.357
2.901GlnSer: 2.901 ± 0.9
1.16GlnThr: 1.16 ± 0.23
1.044GlnVal: 1.044 ± 0.339
0.232GlnTrp: 0.232 ± 0.062
0.464GlnTyr: 0.464 ± 0.123
0.0GlnXaa: 0.0 ± 0.0
Arg
5.222ArgAla: 5.222 ± 0.346
1.392ArgCys: 1.392 ± 0.266
3.713ArgAsp: 3.713 ± 0.622
3.365ArgGlu: 3.365 ± 0.517
3.481ArgPhe: 3.481 ± 0.919
3.249ArgGly: 3.249 ± 0.398
1.044ArgHis: 1.044 ± 0.238
2.669ArgIle: 2.669 ± 0.45
3.829ArgLys: 3.829 ± 0.542
5.686ArgLeu: 5.686 ± 0.889
0.696ArgMet: 0.696 ± 0.403
1.508ArgAsn: 1.508 ± 0.259
1.973ArgPro: 1.973 ± 0.269
2.089ArgGln: 2.089 ± 0.329
6.382ArgArg: 6.382 ± 0.64
6.266ArgSer: 6.266 ± 0.411
2.321ArgThr: 2.321 ± 0.322
6.266ArgVal: 6.266 ± 1.225
0.812ArgTrp: 0.812 ± 0.246
1.857ArgTyr: 1.857 ± 0.68
0.0ArgXaa: 0.0 ± 0.0
Ser
8.239SerAla: 8.239 ± 0.871
1.392SerCys: 1.392 ± 0.392
4.757SerAsp: 4.757 ± 0.73
4.874SerGlu: 4.874 ± 0.392
2.669SerPhe: 2.669 ± 0.362
5.918SerGly: 5.918 ± 1.063
1.741SerHis: 1.741 ± 0.297
4.525SerIle: 4.525 ± 0.972
6.962SerLys: 6.962 ± 0.815
7.89SerLeu: 7.89 ± 1.342
2.553SerMet: 2.553 ± 0.337
5.338SerAsn: 5.338 ± 0.489
5.222SerPro: 5.222 ± 0.931
2.785SerGln: 2.785 ± 1.083
6.034SerArg: 6.034 ± 0.6
12.068SerSer: 12.068 ± 0.814
3.597SerThr: 3.597 ± 0.458
8.471SerVal: 8.471 ± 1.182
1.276SerTrp: 1.276 ± 0.23
3.597SerTyr: 3.597 ± 0.528
0.0SerXaa: 0.0 ± 0.0
Thr
2.669ThrAla: 2.669 ± 0.395
0.348ThrCys: 0.348 ± 0.141
2.205ThrAsp: 2.205 ± 0.399
1.625ThrGlu: 1.625 ± 0.427
4.409ThrPhe: 4.409 ± 0.561
2.669ThrGly: 2.669 ± 0.886
1.16ThrHis: 1.16 ± 0.218
2.321ThrIle: 2.321 ± 0.332
2.437ThrLys: 2.437 ± 0.408
6.382ThrLeu: 6.382 ± 0.973
1.276ThrMet: 1.276 ± 0.236
2.089ThrAsn: 2.089 ± 0.242
3.481ThrPro: 3.481 ± 0.419
1.973ThrGln: 1.973 ± 0.363
2.785ThrArg: 2.785 ± 0.524
4.409ThrSer: 4.409 ± 0.573
4.061ThrThr: 4.061 ± 0.721
4.177ThrVal: 4.177 ± 0.661
0.464ThrTrp: 0.464 ± 0.138
1.741ThrTyr: 1.741 ± 0.456
0.0ThrXaa: 0.0 ± 0.0
Val
8.355ValAla: 8.355 ± 0.618
2.089ValCys: 2.089 ± 0.277
6.266ValAsp: 6.266 ± 0.898
2.901ValGlu: 2.901 ± 0.483
3.249ValPhe: 3.249 ± 0.634
5.802ValGly: 5.802 ± 0.486
2.437ValHis: 2.437 ± 0.468
4.177ValIle: 4.177 ± 0.681
4.757ValLys: 4.757 ± 0.469
5.454ValLeu: 5.454 ± 1.165
2.205ValMet: 2.205 ± 0.211
2.669ValAsn: 2.669 ± 0.393
2.321ValPro: 2.321 ± 0.391
1.625ValGln: 1.625 ± 0.357
5.802ValArg: 5.802 ± 0.348
9.167ValSer: 9.167 ± 0.832
4.293ValThr: 4.293 ± 0.295
8.935ValVal: 8.935 ± 0.873
0.116ValTrp: 0.116 ± 0.168
3.481ValTyr: 3.481 ± 0.297
0.0ValXaa: 0.0 ± 0.0
Trp
0.116TrpAla: 0.116 ± 0.168
0.348TrpCys: 0.348 ± 0.189
0.348TrpAsp: 0.348 ± 0.139
0.116TrpGlu: 0.116 ± 0.168
0.928TrpPhe: 0.928 ± 0.247
0.928TrpGly: 0.928 ± 0.247
0.348TrpHis: 0.348 ± 0.139
0.58TrpIle: 0.58 ± 0.177
1.392TrpLys: 1.392 ± 0.305
0.812TrpLeu: 0.812 ± 0.328
0.58TrpMet: 0.58 ± 0.163
0.348TrpAsn: 0.348 ± 0.189
0.696TrpPro: 0.696 ± 0.185
0.116TrpGln: 0.116 ± 0.078
0.464TrpArg: 0.464 ± 0.123
0.58TrpSer: 0.58 ± 0.134
0.0TrpThr: 0.0 ± 0.0
0.696TrpVal: 0.696 ± 0.141
0.116TrpTrp: 0.116 ± 0.168
0.116TrpTyr: 0.116 ± 0.168
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.741TyrAla: 1.741 ± 0.404
0.232TyrCys: 0.232 ± 0.161
2.437TyrAsp: 2.437 ± 0.887
1.741TyrGlu: 1.741 ± 0.478
1.16TyrPhe: 1.16 ± 0.317
1.857TyrGly: 1.857 ± 0.269
1.276TyrHis: 1.276 ± 0.206
1.741TyrIle: 1.741 ± 0.245
2.669TyrLys: 2.669 ± 0.458
2.089TyrLeu: 2.089 ± 0.575
1.392TyrMet: 1.392 ± 0.282
2.437TyrAsn: 2.437 ± 0.479
1.625TyrPro: 1.625 ± 0.27
2.089TyrGln: 2.089 ± 0.274
2.321TyrArg: 2.321 ± 0.243
2.669TyrSer: 2.669 ± 0.912
1.741TyrThr: 1.741 ± 0.446
3.945TyrVal: 3.945 ± 0.439
0.0TyrTrp: 0.0 ± 0.0
1.741TyrTyr: 1.741 ± 0.344
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (8619 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski