Amino acid dipepetide frequency for Allium cepa amalgavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.19AlaAla: 6.19 ± 1.99
0.0AlaCys: 0.0 ± 0.0
3.439AlaAsp: 3.439 ± 0.425
4.814AlaGlu: 4.814 ± 2.662
2.751AlaPhe: 2.751 ± 0.09
5.502AlaGly: 5.502 ± 0.179
2.063AlaHis: 2.063 ± 0.246
5.502AlaIle: 5.502 ± 0.179
2.063AlaLys: 2.063 ± 0.246
7.565AlaLeu: 7.565 ± 1.319
1.376AlaMet: 1.376 ± 0.582
2.751AlaAsn: 2.751 ± 0.09
2.063AlaPro: 2.063 ± 1.499
0.688AlaGln: 0.688 ± 0.336
12.38AlaArg: 12.38 ± 2.728
9.629AlaSer: 9.629 ± 1.565
3.439AlaThr: 3.439 ± 0.827
6.19AlaVal: 6.19 ± 0.515
0.688AlaTrp: 0.688 ± 0.336
3.439AlaTyr: 3.439 ± 0.425
0.0AlaXaa: 0.0 ± 0.0
Cys
2.063CysAla: 2.063 ± 0.246
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.688CysGlu: 0.688 ± 0.336
1.376CysPhe: 1.376 ± 0.671
0.688CysGly: 0.688 ± 0.336
0.0CysHis: 0.0 ± 0.0
0.688CysIle: 0.688 ± 0.336
1.376CysLys: 1.376 ± 0.582
0.688CysLeu: 0.688 ± 0.336
0.688CysMet: 0.688 ± 0.336
0.688CysAsn: 0.688 ± 0.336
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.688CysVal: 0.688 ± 0.336
1.376CysTrp: 1.376 ± 0.582
0.688CysTyr: 0.688 ± 0.336
0.0CysXaa: 0.0 ± 0.0
Asp
6.878AspAla: 6.878 ± 0.402
0.688AspCys: 0.688 ± 0.336
1.376AspAsp: 1.376 ± 0.671
2.063AspGlu: 2.063 ± 0.246
3.439AspPhe: 3.439 ± 0.425
1.376AspGly: 1.376 ± 0.582
0.0AspHis: 0.0 ± 0.0
5.502AspIle: 5.502 ± 0.179
0.0AspLys: 0.0 ± 0.0
7.565AspLeu: 7.565 ± 0.067
0.688AspMet: 0.688 ± 0.336
3.439AspAsn: 3.439 ± 0.425
4.127AspPro: 4.127 ± 0.492
4.127AspGln: 4.127 ± 1.745
4.127AspArg: 4.127 ± 0.761
6.19AspSer: 6.19 ± 1.99
2.751AspThr: 2.751 ± 0.09
3.439AspVal: 3.439 ± 0.425
2.751AspTrp: 2.751 ± 1.342
2.751AspTyr: 2.751 ± 0.09
0.0AspXaa: 0.0 ± 0.0
Glu
3.439GluAla: 3.439 ± 0.425
2.063GluCys: 2.063 ± 0.246
4.127GluAsp: 4.127 ± 0.761
6.19GluGlu: 6.19 ± 1.99
3.439GluPhe: 3.439 ± 0.827
4.814GluGly: 4.814 ± 0.156
2.751GluHis: 2.751 ± 2.416
1.376GluIle: 1.376 ± 0.582
0.688GluLys: 0.688 ± 0.336
5.502GluLeu: 5.502 ± 1.073
2.751GluMet: 2.751 ± 0.742
2.751GluAsn: 2.751 ± 1.342
0.688GluPro: 0.688 ± 0.336
5.502GluGln: 5.502 ± 1.073
5.502GluArg: 5.502 ± 1.073
2.063GluSer: 2.063 ± 1.499
1.376GluThr: 1.376 ± 0.671
4.814GluVal: 4.814 ± 1.096
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.127PheAla: 4.127 ± 0.492
1.376PheCys: 1.376 ± 0.582
1.376PheAsp: 1.376 ± 0.671
1.376PheGlu: 1.376 ± 0.582
2.063PhePhe: 2.063 ± 1.007
1.376PheGly: 1.376 ± 0.671
0.0PheHis: 0.0 ± 0.0
0.688PheIle: 0.688 ± 0.336
1.376PheLys: 1.376 ± 0.671
4.814PheLeu: 4.814 ± 1.096
1.376PheMet: 1.376 ± 0.671
2.063PheAsn: 2.063 ± 1.007
2.751PhePro: 2.751 ± 0.09
0.0PheGln: 0.0 ± 0.0
6.19PheArg: 6.19 ± 1.767
2.063PheSer: 2.063 ± 1.007
4.127PheThr: 4.127 ± 0.492
5.502PheVal: 5.502 ± 2.684
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.127GlyAla: 4.127 ± 0.492
0.688GlyCys: 0.688 ± 0.336
4.127GlyAsp: 4.127 ± 1.745
5.502GlyGlu: 5.502 ± 0.179
2.063GlyPhe: 2.063 ± 1.007
6.878GlyGly: 6.878 ± 0.402
0.0GlyHis: 0.0 ± 0.0
4.127GlyIle: 4.127 ± 2.013
1.376GlyLys: 1.376 ± 0.671
2.063GlyLeu: 2.063 ± 1.007
1.376GlyMet: 1.376 ± 0.671
3.439GlyAsn: 3.439 ± 0.425
2.751GlyPro: 2.751 ± 1.163
2.063GlyGln: 2.063 ± 1.499
4.127GlyArg: 4.127 ± 0.761
2.063GlySer: 2.063 ± 0.246
2.063GlyThr: 2.063 ± 1.007
4.127GlyVal: 4.127 ± 0.492
0.688GlyTrp: 0.688 ± 0.336
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.063HisAla: 2.063 ± 1.499
0.688HisCys: 0.688 ± 0.336
1.376HisAsp: 1.376 ± 0.582
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.688HisHis: 0.688 ± 0.336
0.688HisIle: 0.688 ± 0.336
0.0HisLys: 0.0 ± 0.0
4.814HisLeu: 4.814 ± 1.409
0.0HisMet: 0.0 ± 0.0
2.063HisAsn: 2.063 ± 0.246
0.688HisPro: 0.688 ± 0.336
0.688HisGln: 0.688 ± 0.917
4.127HisArg: 4.127 ± 0.492
2.063HisSer: 2.063 ± 1.499
0.688HisThr: 0.688 ± 0.917
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.063IleAla: 2.063 ± 0.246
0.688IleCys: 0.688 ± 0.336
5.502IleAsp: 5.502 ± 1.432
4.814IleGlu: 4.814 ± 1.096
0.688IlePhe: 0.688 ± 0.336
4.127IleGly: 4.127 ± 0.761
2.751IleHis: 2.751 ± 0.09
2.063IleIle: 2.063 ± 1.007
1.376IleLys: 1.376 ± 0.671
6.878IleLeu: 6.878 ± 0.85
0.0IleMet: 0.0 ± 0.0
4.814IleAsn: 4.814 ± 0.156
2.751IlePro: 2.751 ± 0.09
1.376IleGln: 1.376 ± 0.582
4.814IleArg: 4.814 ± 1.096
2.751IleSer: 2.751 ± 0.09
1.376IleThr: 1.376 ± 0.582
2.751IleVal: 2.751 ± 0.09
0.0IleTrp: 0.0 ± 0.0
0.688IleTyr: 0.688 ± 0.336
0.0IleXaa: 0.0 ± 0.0
Lys
4.814LysAla: 4.814 ± 0.156
0.688LysCys: 0.688 ± 0.336
0.688LysAsp: 0.688 ± 0.336
1.376LysGlu: 1.376 ± 0.582
2.751LysPhe: 2.751 ± 1.342
0.688LysGly: 0.688 ± 0.336
2.063LysHis: 2.063 ± 1.499
4.814LysIle: 4.814 ± 1.409
6.19LysLys: 6.19 ± 3.243
2.063LysLeu: 2.063 ± 1.007
0.688LysMet: 0.688 ± 0.336
4.127LysAsn: 4.127 ± 0.492
2.063LysPro: 2.063 ± 0.246
1.376LysGln: 1.376 ± 0.582
5.502LysArg: 5.502 ± 2.326
0.688LysSer: 0.688 ± 0.336
0.688LysThr: 0.688 ± 0.336
3.439LysVal: 3.439 ± 1.678
0.688LysTrp: 0.688 ± 0.336
1.376LysTyr: 1.376 ± 0.671
0.0LysXaa: 0.0 ± 0.0
Leu
8.941LeuAla: 8.941 ± 1.901
0.0LeuCys: 0.0 ± 0.0
7.565LeuAsp: 7.565 ± 0.067
1.376LeuGlu: 1.376 ± 0.671
2.063LeuPhe: 2.063 ± 1.007
2.751LeuGly: 2.751 ± 0.09
0.0LeuHis: 0.0 ± 0.0
1.376LeuIle: 1.376 ± 0.671
6.878LeuLys: 6.878 ± 0.402
13.755LeuLeu: 13.755 ± 0.448
0.0LeuMet: 0.0 ± 0.0
2.751LeuAsn: 2.751 ± 1.342
6.878LeuPro: 6.878 ± 0.85
6.19LeuGln: 6.19 ± 1.99
9.629LeuArg: 9.629 ± 0.313
11.004LeuSer: 11.004 ± 0.358
3.439LeuThr: 3.439 ± 0.425
1.376LeuVal: 1.376 ± 0.671
2.751LeuTrp: 2.751 ± 1.342
3.439LeuTyr: 3.439 ± 0.425
0.0LeuXaa: 0.0 ± 0.0
Met
2.063MetAla: 2.063 ± 1.499
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.688MetGlu: 0.688 ± 0.336
0.688MetPhe: 0.688 ± 0.336
1.376MetGly: 1.376 ± 0.582
0.688MetHis: 0.688 ± 0.336
2.063MetIle: 2.063 ± 1.007
0.0MetLys: 0.0 ± 0.0
2.751MetLeu: 2.751 ± 0.09
1.376MetMet: 1.376 ± 0.671
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
1.376MetGln: 1.376 ± 0.671
2.751MetArg: 2.751 ± 0.09
1.376MetSer: 1.376 ± 0.582
1.376MetThr: 1.376 ± 0.671
3.439MetVal: 3.439 ± 0.425
0.688MetTrp: 0.688 ± 0.336
0.688MetTyr: 0.688 ± 0.336
0.0MetXaa: 0.0 ± 0.0
Asn
6.19AsnAla: 6.19 ± 0.515
0.0AsnCys: 0.0 ± 0.0
4.127AsnAsp: 4.127 ± 0.761
2.751AsnGlu: 2.751 ± 1.163
2.063AsnPhe: 2.063 ± 0.246
1.376AsnGly: 1.376 ± 0.671
1.376AsnHis: 1.376 ± 0.671
3.439AsnIle: 3.439 ± 0.425
4.127AsnLys: 4.127 ± 0.492
2.063AsnLeu: 2.063 ± 0.246
0.688AsnMet: 0.688 ± 0.336
2.751AsnAsn: 2.751 ± 0.09
2.063AsnPro: 2.063 ± 1.007
3.439AsnGln: 3.439 ± 0.827
2.063AsnArg: 2.063 ± 0.246
2.063AsnSer: 2.063 ± 1.007
1.376AsnThr: 1.376 ± 0.671
4.127AsnVal: 4.127 ± 0.492
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.127ProAla: 4.127 ± 1.745
0.688ProCys: 0.688 ± 0.336
4.814ProAsp: 4.814 ± 1.409
3.439ProGlu: 3.439 ± 0.827
3.439ProPhe: 3.439 ± 1.678
0.688ProGly: 0.688 ± 0.336
0.0ProHis: 0.0 ± 0.0
2.751ProIle: 2.751 ± 1.342
1.376ProLys: 1.376 ± 0.671
2.751ProLeu: 2.751 ± 1.342
2.063ProMet: 2.063 ± 1.196
0.688ProAsn: 0.688 ± 0.917
4.127ProPro: 4.127 ± 0.492
1.376ProGln: 1.376 ± 0.582
0.688ProArg: 0.688 ± 0.336
5.502ProSer: 5.502 ± 2.326
4.127ProThr: 4.127 ± 0.761
2.063ProVal: 2.063 ± 0.246
1.376ProTrp: 1.376 ± 0.582
0.688ProTyr: 0.688 ± 0.336
0.0ProXaa: 0.0 ± 0.0
Gln
3.439GlnAla: 3.439 ± 0.425
0.0GlnCys: 0.0 ± 0.0
6.19GlnAsp: 6.19 ± 1.99
6.19GlnGlu: 6.19 ± 1.99
2.063GlnPhe: 2.063 ± 0.246
1.376GlnGly: 1.376 ± 0.582
4.814GlnHis: 4.814 ± 2.662
2.063GlnIle: 2.063 ± 0.246
0.0GlnLys: 0.0 ± 0.0
0.688GlnLeu: 0.688 ± 0.336
2.063GlnMet: 2.063 ± 0.246
0.0GlnAsn: 0.0 ± 0.0
0.688GlnPro: 0.688 ± 0.917
2.751GlnGln: 2.751 ± 1.163
4.127GlnArg: 4.127 ± 0.492
1.376GlnSer: 1.376 ± 0.671
2.751GlnThr: 2.751 ± 1.163
4.814GlnVal: 4.814 ± 0.156
0.0GlnTrp: 0.0 ± 0.0
2.751GlnTyr: 2.751 ± 0.09
0.0GlnXaa: 0.0 ± 0.0
Arg
5.502ArgAla: 5.502 ± 0.179
2.063ArgCys: 2.063 ± 1.007
8.253ArgAsp: 8.253 ± 0.984
5.502ArgGlu: 5.502 ± 0.179
6.878ArgPhe: 6.878 ± 0.85
6.878ArgGly: 6.878 ± 0.85
0.688ArgHis: 0.688 ± 0.917
3.439ArgIle: 3.439 ± 0.827
4.127ArgLys: 4.127 ± 1.745
6.19ArgLeu: 6.19 ± 0.515
2.063ArgMet: 2.063 ± 0.246
3.439ArgAsn: 3.439 ± 0.425
4.814ArgPro: 4.814 ± 2.349
6.878ArgGln: 6.878 ± 0.85
6.19ArgArg: 6.19 ± 1.99
6.19ArgSer: 6.19 ± 0.515
3.439ArgThr: 3.439 ± 0.425
5.502ArgVal: 5.502 ± 2.326
2.063ArgTrp: 2.063 ± 0.246
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.063SerAla: 2.063 ± 0.246
0.688SerCys: 0.688 ± 0.336
5.502SerAsp: 5.502 ± 1.073
2.751SerGlu: 2.751 ± 1.163
2.751SerPhe: 2.751 ± 0.09
6.19SerGly: 6.19 ± 1.99
1.376SerHis: 1.376 ± 0.582
4.814SerIle: 4.814 ± 0.156
6.878SerLys: 6.878 ± 1.655
6.19SerLeu: 6.19 ± 0.515
2.063SerMet: 2.063 ± 0.246
5.502SerAsn: 5.502 ± 0.179
1.376SerPro: 1.376 ± 0.671
3.439SerGln: 3.439 ± 0.425
4.127SerArg: 4.127 ± 0.761
10.316SerSer: 10.316 ± 1.23
2.063SerThr: 2.063 ± 0.246
4.127SerVal: 4.127 ± 0.492
3.439SerTrp: 3.439 ± 1.678
0.688SerTyr: 0.688 ± 0.336
0.0SerXaa: 0.0 ± 0.0
Thr
6.19ThrAla: 6.19 ± 0.738
0.0ThrCys: 0.0 ± 0.0
2.063ThrAsp: 2.063 ± 1.007
2.751ThrGlu: 2.751 ± 0.09
0.0ThrPhe: 0.0 ± 0.0
1.376ThrGly: 1.376 ± 0.671
1.376ThrHis: 1.376 ± 0.671
1.376ThrIle: 1.376 ± 0.671
2.063ThrLys: 2.063 ± 1.007
2.751ThrLeu: 2.751 ± 0.09
0.688ThrMet: 0.688 ± 0.336
2.751ThrAsn: 2.751 ± 1.163
4.814ThrPro: 4.814 ± 2.662
2.063ThrGln: 2.063 ± 0.246
2.751ThrArg: 2.751 ± 0.09
3.439ThrSer: 3.439 ± 0.425
1.376ThrThr: 1.376 ± 0.582
1.376ThrVal: 1.376 ± 0.671
2.063ThrTrp: 2.063 ± 0.246
0.688ThrTyr: 0.688 ± 0.336
0.0ThrXaa: 0.0 ± 0.0
Val
4.127ValAla: 4.127 ± 0.492
0.0ValCys: 0.0 ± 0.0
2.751ValAsp: 2.751 ± 1.342
4.127ValGlu: 4.127 ± 0.761
2.751ValPhe: 2.751 ± 1.342
4.814ValGly: 4.814 ± 1.096
0.0ValHis: 0.0 ± 0.0
4.814ValIle: 4.814 ± 1.096
4.127ValLys: 4.127 ± 0.492
6.878ValLeu: 6.878 ± 0.402
2.063ValMet: 2.063 ± 0.246
0.0ValAsn: 0.0 ± 0.0
4.127ValPro: 4.127 ± 0.761
4.127ValGln: 4.127 ± 1.745
6.19ValArg: 6.19 ± 0.515
6.19ValSer: 6.19 ± 1.767
4.814ValThr: 4.814 ± 0.156
1.376ValVal: 1.376 ± 0.671
0.688ValTrp: 0.688 ± 0.336
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
2.751TrpAla: 2.751 ± 0.09
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.751TrpGlu: 2.751 ± 0.09
0.688TrpPhe: 0.688 ± 0.336
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.688TrpIle: 0.688 ± 0.336
2.063TrpLys: 2.063 ± 1.007
3.439TrpLeu: 3.439 ± 0.425
0.688TrpMet: 0.688 ± 0.336
1.376TrpAsn: 1.376 ± 0.582
0.0TrpPro: 0.0 ± 0.0
0.688TrpGln: 0.688 ± 0.336
2.063TrpArg: 2.063 ± 1.007
0.0TrpSer: 0.0 ± 0.0
0.688TrpThr: 0.688 ± 0.336
2.063TrpVal: 2.063 ± 1.007
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.376TyrAla: 1.376 ± 0.582
1.376TyrCys: 1.376 ± 0.582
0.0TyrAsp: 0.0 ± 0.0
0.688TyrGlu: 0.688 ± 0.336
0.688TyrPhe: 0.688 ± 0.336
1.376TyrGly: 1.376 ± 0.671
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.688TyrLys: 0.688 ± 0.336
2.751TyrLeu: 2.751 ± 0.09
0.0TyrMet: 0.0 ± 0.0
0.688TyrAsn: 0.688 ± 0.336
0.688TyrPro: 0.688 ± 0.336
0.0TyrGln: 0.0 ± 0.0
2.751TyrArg: 2.751 ± 1.342
1.376TyrSer: 1.376 ± 0.671
0.0TyrThr: 0.0 ± 0.0
2.751TyrVal: 2.751 ± 0.09
0.688TyrTrp: 0.688 ± 0.336
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1455 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski