Amino acid dipepetide frequency for Cyphellophora europaea CBS 101466

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.975AlaAla: 9.975 ± 0.06	1.058AlaCys: 1.058 ± 0.015	4.693AlaAsp: 4.693 ± 0.032	5.45AlaGlu: 5.45 ± 0.042	3.27AlaPhe: 3.27 ± 0.03	6.395AlaGly: 6.395 ± 0.039	1.901AlaHis: 1.901 ± 0.019	4.28AlaIle: 4.28 ± 0.031	4.16AlaLys: 4.16 ± 0.035	8.087AlaLeu: 8.087 ± 0.045	2.112AlaMet: 2.112 ± 0.022	3.12AlaAsn: 3.12 ± 0.023	4.95AlaPro: 4.95 ± 0.045	3.719AlaGln: 3.719 ± 0.033	5.294AlaArg: 5.294 ± 0.034	7.596AlaSer: 7.596 ± 0.05	5.644AlaThr: 5.644 ± 0.034	5.713AlaVal: 5.713 ± 0.037	1.24AlaTrp: 1.24 ± 0.015	2.279AlaTyr: 2.279 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.931CysAla: 0.931 ± 0.013	0.22CysCys: 0.22 ± 0.006	0.597CysAsp: 0.597 ± 0.012	0.55CysGlu: 0.55 ± 0.012	0.512CysPhe: 0.512 ± 0.01	0.898CysGly: 0.898 ± 0.013	0.304CysHis: 0.304 ± 0.006	0.671CysIle: 0.671 ± 0.012	0.473CysLys: 0.473 ± 0.009	1.22CysLeu: 1.22 ± 0.016	0.259CysMet: 0.259 ± 0.007	0.401CysAsn: 0.401 ± 0.009	0.589CysPro: 0.589 ± 0.012	0.417CysGln: 0.417 ± 0.009	0.685CysArg: 0.685 ± 0.012	0.799CysSer: 0.799 ± 0.014	0.66CysThr: 0.66 ± 0.012	0.781CysVal: 0.781 ± 0.014	0.211CysTrp: 0.211 ± 0.007	0.352CysTyr: 0.352 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	5.138AspAla: 5.138 ± 0.033	0.582AspCys: 0.582 ± 0.009	4.379AspAsp: 4.379 ± 0.039	4.516AspGlu: 4.516 ± 0.037	2.264AspPhe: 2.264 ± 0.021	4.155AspGly: 4.155 ± 0.031	1.296AspHis: 1.296 ± 0.017	2.804AspIle: 2.804 ± 0.022	2.361AspLys: 2.361 ± 0.024	5.143AspLeu: 5.143 ± 0.04	1.285AspMet: 1.285 ± 0.013	1.865AspAsn: 1.865 ± 0.02	3.383AspPro: 3.383 ± 0.027	1.998AspGln: 1.998 ± 0.021	3.154AspArg: 3.154 ± 0.026	4.066AspSer: 4.066 ± 0.031	3.024AspThr: 3.024 ± 0.025	3.85AspVal: 3.85 ± 0.025	0.906AspTrp: 0.906 ± 0.013	1.584AspTyr: 1.584 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.679GluAla: 5.679 ± 0.04	0.587GluCys: 0.587 ± 0.013	4.171GluAsp: 4.171 ± 0.035	5.073GluGlu: 5.073 ± 0.045	1.741GluPhe: 1.741 ± 0.018	4.011GluGly: 4.011 ± 0.032	1.449GluHis: 1.449 ± 0.018	2.78GluIle: 2.78 ± 0.024	3.462GluLys: 3.462 ± 0.033	5.127GluLeu: 5.127 ± 0.036	1.454GluMet: 1.454 ± 0.018	2.008GluAsn: 2.008 ± 0.018	2.752GluPro: 2.752 ± 0.03	2.68GluGln: 2.68 ± 0.028	4.016GluArg: 4.016 ± 0.032	4.08GluSer: 4.08 ± 0.031	3.31GluThr: 3.31 ± 0.028	3.794GluVal: 3.794 ± 0.03	0.902GluTrp: 0.902 ± 0.013	1.56GluTyr: 1.56 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.201PheAla: 3.201 ± 0.026	0.525PheCys: 0.525 ± 0.01	2.31PheAsp: 2.31 ± 0.021	2.146PheGlu: 2.146 ± 0.021	1.597PhePhe: 1.597 ± 0.021	2.89PheGly: 2.89 ± 0.031	0.834PheHis: 0.834 ± 0.011	1.655PheIle: 1.655 ± 0.021	1.391PheLys: 1.391 ± 0.016	3.313PheLeu: 3.313 ± 0.034	0.793PheMet: 0.793 ± 0.013	1.366PheAsn: 1.366 ± 0.016	1.857PhePro: 1.857 ± 0.02	1.357PheGln: 1.357 ± 0.017	1.924PheArg: 1.924 ± 0.018	2.803PheSer: 2.803 ± 0.027	2.066PheThr: 2.066 ± 0.019	2.41PheVal: 2.41 ± 0.022	0.647PheTrp: 0.647 ± 0.012	1.077PheTyr: 1.077 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.719GlyAla: 5.719 ± 0.037	0.819GlyCys: 0.819 ± 0.014	3.7GlyAsp: 3.7 ± 0.031	3.793GlyGlu: 3.793 ± 0.031	2.844GlyPhe: 2.844 ± 0.026	6.324GlyGly: 6.324 ± 0.057	1.698GlyHis: 1.698 ± 0.018	3.453GlyIle: 3.453 ± 0.029	3.475GlyLys: 3.475 ± 0.029	6.3GlyLeu: 6.3 ± 0.039	1.756GlyMet: 1.756 ± 0.021	2.461GlyAsn: 2.461 ± 0.024	3.435GlyPro: 3.435 ± 0.033	2.773GlyGln: 2.773 ± 0.025	4.345GlyArg: 4.345 ± 0.034	5.646GlySer: 5.646 ± 0.037	4.08GlyThr: 4.08 ± 0.034	4.638GlyVal: 4.638 ± 0.034	1.285GlyTrp: 1.285 ± 0.017	2.158GlyTyr: 2.158 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	2.005HisAla: 2.005 ± 0.021	0.315HisCys: 0.315 ± 0.009	1.409HisAsp: 1.409 ± 0.015	1.348HisGlu: 1.348 ± 0.015	0.924HisPhe: 0.924 ± 0.013	1.748HisGly: 1.748 ± 0.02	0.831HisHis: 0.831 ± 0.015	1.163HisIle: 1.163 ± 0.015	0.924HisLys: 0.924 ± 0.013	2.25HisLeu: 2.25 ± 0.02	0.496HisMet: 0.496 ± 0.011	0.838HisAsn: 0.838 ± 0.012	1.62HisPro: 1.62 ± 0.017	0.999HisGln: 0.999 ± 0.016	1.535HisArg: 1.535 ± 0.019	1.799HisSer: 1.799 ± 0.021	1.284HisThr: 1.284 ± 0.016	1.472HisVal: 1.472 ± 0.018	0.359HisTrp: 0.359 ± 0.008	0.705HisTyr: 0.705 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.195IleAla: 4.195 ± 0.032	0.679IleCys: 0.679 ± 0.013	2.881IleAsp: 2.881 ± 0.024	2.736IleGlu: 2.736 ± 0.026	1.875IlePhe: 1.875 ± 0.02	3.144IleGly: 3.144 ± 0.029	1.112IleHis: 1.112 ± 0.013	2.284IleIle: 2.284 ± 0.025	2.002IleLys: 2.002 ± 0.02	4.204IleLeu: 4.204 ± 0.028	0.984IleMet: 0.984 ± 0.013	1.725IleAsn: 1.725 ± 0.017	2.817IlePro: 2.817 ± 0.024	1.728IleGln: 1.728 ± 0.019	2.632IleArg: 2.632 ± 0.025	3.548IleSer: 3.548 ± 0.027	2.722IleThr: 2.722 ± 0.023	3.087IleVal: 3.087 ± 0.029	0.717IleTrp: 0.717 ± 0.012	1.338IleTyr: 1.338 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.345LysAla: 4.345 ± 0.034	0.456LysCys: 0.456 ± 0.011	2.75LysAsp: 2.75 ± 0.027	3.152LysGlu: 3.152 ± 0.03	1.348LysPhe: 1.348 ± 0.017	2.966LysGly: 2.966 ± 0.029	1.187LysHis: 1.187 ± 0.014	2.065LysIle: 2.065 ± 0.023	3.091LysLys: 3.091 ± 0.046	3.927LysLeu: 3.927 ± 0.026	0.991LysMet: 0.991 ± 0.013	1.525LysAsn: 1.525 ± 0.018	2.748LysPro: 2.748 ± 0.029	1.958LysGln: 1.958 ± 0.021	3.424LysArg: 3.424 ± 0.028	3.377LysSer: 3.377 ± 0.029	2.708LysThr: 2.708 ± 0.025	2.798LysVal: 2.798 ± 0.024	0.666LysTrp: 0.666 ± 0.012	1.283LysTyr: 1.283 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.204LeuAla: 8.204 ± 0.049	1.189LeuCys: 1.189 ± 0.017	5.149LeuAsp: 5.149 ± 0.033	5.342LeuGlu: 5.342 ± 0.038	3.217LeuPhe: 3.217 ± 0.03	5.992LeuGly: 5.992 ± 0.036	2.209LeuHis: 2.209 ± 0.023	3.804LeuIle: 3.804 ± 0.035	4.055LeuLys: 4.055 ± 0.031	8.359LeuLeu: 8.359 ± 0.055	1.857LeuMet: 1.857 ± 0.021	3.122LeuAsn: 3.122 ± 0.028	5.487LeuPro: 5.487 ± 0.035	3.875LeuGln: 3.875 ± 0.026	5.722LeuArg: 5.722 ± 0.038	7.121LeuSer: 7.121 ± 0.041	4.983LeuThr: 4.983 ± 0.034	5.388LeuVal: 5.388 ± 0.044	1.255LeuTrp: 1.255 ± 0.017	2.305LeuTyr: 2.305 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.302MetAla: 2.302 ± 0.02	0.263MetCys: 0.263 ± 0.007	1.195MetAsp: 1.195 ± 0.016	1.178MetGlu: 1.178 ± 0.014	0.773MetPhe: 0.773 ± 0.014	1.541MetGly: 1.541 ± 0.018	0.528MetHis: 0.528 ± 0.01	0.944MetIle: 0.944 ± 0.014	0.964MetLys: 0.964 ± 0.013	1.974MetLeu: 1.974 ± 0.019	0.57MetMet: 0.57 ± 0.012	0.797MetAsn: 0.797 ± 0.012	1.389MetPro: 1.389 ± 0.015	0.963MetGln: 0.963 ± 0.016	1.308MetArg: 1.308 ± 0.015	1.935MetSer: 1.935 ± 0.02	1.334MetThr: 1.334 ± 0.016	1.314MetVal: 1.314 ± 0.015	0.27MetTrp: 0.27 ± 0.007	0.546MetTyr: 0.546 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.317AsnAla: 3.317 ± 0.029	0.387AsnCys: 0.387 ± 0.008	1.981AsnAsp: 1.981 ± 0.02	1.967AsnGlu: 1.967 ± 0.018	1.33AsnPhe: 1.33 ± 0.016	2.961AsnGly: 2.961 ± 0.028	0.824AsnHis: 0.824 ± 0.011	1.878AsnIle: 1.878 ± 0.019	1.483AsnLys: 1.483 ± 0.021	3.129AsnLeu: 3.129 ± 0.027	0.792AsnMet: 0.792 ± 0.013	1.403AsnAsn: 1.403 ± 0.018	2.301AsnPro: 2.301 ± 0.024	1.302AsnGln: 1.302 ± 0.015	1.829AsnArg: 1.829 ± 0.02	2.537AsnSer: 2.537 ± 0.024	2.11AsnThr: 2.11 ± 0.021	2.366AsnVal: 2.366 ± 0.021	0.523AsnTrp: 0.523 ± 0.01	1.015AsnTyr: 1.015 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.524ProAla: 5.524 ± 0.049	0.454ProCys: 0.454 ± 0.01	3.243ProAsp: 3.243 ± 0.025	3.78ProGlu: 3.78 ± 0.03	2.028ProPhe: 2.028 ± 0.021	3.944ProGly: 3.944 ± 0.036	1.358ProHis: 1.358 ± 0.018	2.384ProIle: 2.384 ± 0.021	2.578ProLys: 2.578 ± 0.026	4.655ProLeu: 4.655 ± 0.029	1.116ProMet: 1.116 ± 0.018	2.196ProAsn: 2.196 ± 0.023	5.254ProPro: 5.254 ± 0.069	2.599ProGln: 2.599 ± 0.027	3.435ProArg: 3.435 ± 0.029	5.941ProSer: 5.941 ± 0.042	4.162ProThr: 4.162 ± 0.036	3.513ProVal: 3.513 ± 0.03	0.733ProTrp: 0.733 ± 0.012	1.509ProTyr: 1.509 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.759GlnAla: 3.759 ± 0.03	0.428GlnCys: 0.428 ± 0.01	2.188GlnAsp: 2.188 ± 0.022	2.418GlnGlu: 2.418 ± 0.023	1.24GlnPhe: 1.24 ± 0.016	2.599GlnGly: 2.599 ± 0.026	1.204GlnHis: 1.204 ± 0.015	1.86GlnIle: 1.86 ± 0.018	1.971GlnLys: 1.971 ± 0.021	3.537GlnLeu: 3.537 ± 0.028	0.932GlnMet: 0.932 ± 0.015	1.499GlnAsn: 1.499 ± 0.019	2.69GlnPro: 2.69 ± 0.026	2.772GlnGln: 2.772 ± 0.043	2.878GlnArg: 2.878 ± 0.026	3.224GlnSer: 3.224 ± 0.031	2.358GlnThr: 2.358 ± 0.022	2.276GlnVal: 2.276 ± 0.022	0.592GlnTrp: 0.592 ± 0.009	1.214GlnTyr: 1.214 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.052ArgAla: 5.052 ± 0.033	0.683ArgCys: 0.683 ± 0.013	3.458ArgAsp: 3.458 ± 0.031	3.811ArgGlu: 3.811 ± 0.031	2.07ArgPhe: 2.07 ± 0.021	3.91ArgGly: 3.91 ± 0.03	1.596ArgHis: 1.596 ± 0.02	2.746ArgIle: 2.746 ± 0.03	3.488ArgLys: 3.488 ± 0.03	5.467ArgLeu: 5.467 ± 0.029	1.378ArgMet: 1.378 ± 0.018	2.207ArgAsn: 2.207 ± 0.02	3.613ArgPro: 3.613 ± 0.035	2.773ArgGln: 2.773 ± 0.028	5.183ArgArg: 5.183 ± 0.046	4.867ArgSer: 4.867 ± 0.038	3.379ArgThr: 3.379 ± 0.024	3.414ArgVal: 3.414 ± 0.029	1.007ArgTrp: 1.007 ± 0.013	1.702ArgTyr: 1.702 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.944SerAla: 6.944 ± 0.045	0.773SerCys: 0.773 ± 0.013	4.266SerAsp: 4.266 ± 0.03	4.087SerGlu: 4.087 ± 0.03	2.805SerPhe: 2.805 ± 0.024	5.567SerGly: 5.567 ± 0.041	1.866SerHis: 1.866 ± 0.024	3.838SerIle: 3.838 ± 0.027	3.658SerLys: 3.658 ± 0.033	6.912SerLeu: 6.912 ± 0.039	1.751SerMet: 1.751 ± 0.022	2.935SerAsn: 2.935 ± 0.027	5.501SerPro: 5.501 ± 0.055	3.274SerGln: 3.274 ± 0.029	4.963SerArg: 4.963 ± 0.041	8.299SerSer: 8.299 ± 0.069	5.664SerThr: 5.664 ± 0.04	4.51SerVal: 4.51 ± 0.032	1.098SerTrp: 1.098 ± 0.016	2.026SerTyr: 2.026 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.531ThrAla: 5.531 ± 0.033	0.695ThrCys: 0.695 ± 0.013	2.99ThrAsp: 2.99 ± 0.021	3.089ThrGlu: 3.089 ± 0.027	2.227ThrPhe: 2.227 ± 0.018	4.229ThrGly: 4.229 ± 0.029	1.29ThrHis: 1.29 ± 0.015	2.986ThrIle: 2.986 ± 0.03	2.581ThrLys: 2.581 ± 0.023	5.235ThrLeu: 5.235 ± 0.035	1.225ThrMet: 1.225 ± 0.015	2.135ThrAsn: 2.135 ± 0.022	4.316ThrPro: 4.316 ± 0.036	2.2ThrGln: 2.2 ± 0.023	3.137ThrArg: 3.137 ± 0.025	5.491ThrSer: 5.491 ± 0.043	4.446ThrThr: 4.446 ± 0.047	3.721ThrVal: 3.721 ± 0.033	0.886ThrTrp: 0.886 ± 0.015	1.615ThrTyr: 1.615 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.616ValAla: 5.616 ± 0.038	0.814ValCys: 0.814 ± 0.015	3.813ValAsp: 3.813 ± 0.027	3.865ValGlu: 3.865 ± 0.029	2.37ValPhe: 2.37 ± 0.025	4.307ValGly: 4.307 ± 0.03	1.398ValHis: 1.398 ± 0.017	2.767ValIle: 2.767 ± 0.024	2.852ValLys: 2.852 ± 0.024	5.714ValLeu: 5.714 ± 0.041	1.344ValMet: 1.344 ± 0.017	2.191ValAsn: 2.191 ± 0.021	3.651ValPro: 3.651 ± 0.03	2.49ValGln: 2.49 ± 0.02	3.674ValArg: 3.674 ± 0.024	4.588ValSer: 4.588 ± 0.032	3.503ValThr: 3.503 ± 0.027	4.472ValVal: 4.472 ± 0.035	0.932ValTrp: 0.932 ± 0.015	1.693ValTyr: 1.693 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.199TrpAla: 1.199 ± 0.016	0.196TrpCys: 0.196 ± 0.006	0.868TrpAsp: 0.868 ± 0.013	0.836TrpGlu: 0.836 ± 0.013	0.568TrpPhe: 0.568 ± 0.011	0.972TrpGly: 0.972 ± 0.015	0.393TrpHis: 0.393 ± 0.008	0.759TrpIle: 0.759 ± 0.013	0.758TrpLys: 0.758 ± 0.013	1.446TrpLeu: 1.446 ± 0.02	0.395TrpMet: 0.395 ± 0.009	0.576TrpAsn: 0.576 ± 0.011	0.629TrpPro: 0.629 ± 0.012	0.648TrpGln: 0.648 ± 0.01	1.046TrpArg: 1.046 ± 0.014	1.072TrpSer: 1.072 ± 0.015	0.963TrpThr: 0.963 ± 0.015	0.887TrpVal: 0.887 ± 0.013	0.3TrpTrp: 0.3 ± 0.008	0.459TrpTyr: 0.459 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.3TyrAla: 2.3 ± 0.021	0.404TyrCys: 0.404 ± 0.01	1.712TyrAsp: 1.712 ± 0.018	1.501TyrGlu: 1.501 ± 0.018	1.159TyrPhe: 1.159 ± 0.016	2.149TyrGly: 2.149 ± 0.021	0.748TyrHis: 0.748 ± 0.013	1.291TyrIle: 1.291 ± 0.016	1.04TyrLys: 1.04 ± 0.013	2.633TyrLeu: 2.633 ± 0.023	0.595TyrMet: 0.595 ± 0.012	1.069TyrAsn: 1.069 ± 0.014	1.426TyrPro: 1.426 ± 0.019	1.116TyrGln: 1.116 ± 0.015	1.621TyrArg: 1.621 ± 0.018	1.944TyrSer: 1.944 ± 0.02	1.622TyrThr: 1.622 ± 0.018	1.65TyrVal: 1.65 ± 0.018	0.439TyrTrp: 0.439 ± 0.011	0.885TyrTyr: 0.885 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11090 proteins (5402066 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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