Amino acid dipepetide frequency for Wenzhou crab virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.168AlaAla: 7.168 ± 2.39
2.389AlaCys: 2.389 ± 0.658
3.584AlaAsp: 3.584 ± 0.705
1.792AlaGlu: 1.792 ± 0.614
1.195AlaPhe: 1.195 ± 0.829
6.571AlaGly: 6.571 ± 0.593
3.584AlaHis: 3.584 ± 0.971
1.195AlaIle: 1.195 ± 0.381
3.584AlaLys: 3.584 ± 1.671
8.363AlaLeu: 8.363 ± 1.198
1.792AlaMet: 1.792 ± 0.778
2.987AlaAsn: 2.987 ± 1.074
5.376AlaPro: 5.376 ± 1.61
4.182AlaGln: 4.182 ± 0.966
5.974AlaArg: 5.974 ± 1.868
2.987AlaSer: 2.987 ± 1.121
8.363AlaThr: 8.363 ± 0.859
8.363AlaVal: 8.363 ± 1.198
1.195AlaTrp: 1.195 ± 0.381
1.792AlaTyr: 1.792 ± 1.318
0.0AlaXaa: 0.0 ± 0.0
Cys
1.195CysAla: 1.195 ± 0.829
1.195CysCys: 1.195 ± 1.014
2.389CysAsp: 2.389 ± 1.278
0.0CysGlu: 0.0 ± 0.0
1.195CysPhe: 1.195 ± 0.829
1.195CysGly: 1.195 ± 0.733
1.195CysHis: 1.195 ± 1.014
1.195CysIle: 1.195 ± 0.829
0.0CysLys: 0.0 ± 0.0
2.987CysLeu: 2.987 ± 0.934
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.389CysPro: 2.389 ± 0.232
2.389CysGln: 2.389 ± 0.232
1.792CysArg: 1.792 ± 0.614
1.792CysSer: 1.792 ± 1.521
0.597CysThr: 0.597 ± 0.414
1.195CysVal: 1.195 ± 0.829
0.0CysTrp: 0.0 ± 0.0
0.597CysTyr: 0.597 ± 0.414
0.0CysXaa: 0.0 ± 0.0
Asp
5.376AspAla: 5.376 ± 0.925
0.597AspCys: 0.597 ± 0.414
2.987AspAsp: 2.987 ± 1.074
1.195AspGlu: 1.195 ± 0.829
6.571AspPhe: 6.571 ± 0.593
3.584AspGly: 3.584 ± 0.971
0.0AspHis: 0.0 ± 0.0
2.389AspIle: 2.389 ± 1.467
4.182AspLys: 4.182 ± 0.927
4.182AspLeu: 4.182 ± 1.354
0.597AspMet: 0.597 ± 0.507
2.389AspAsn: 2.389 ± 0.975
4.779AspPro: 4.779 ± 2.059
1.792AspGln: 1.792 ± 1.243
4.779AspArg: 4.779 ± 1.038
2.987AspSer: 2.987 ± 1.775
2.389AspThr: 2.389 ± 0.232
2.987AspVal: 2.987 ± 2.071
1.195AspTrp: 1.195 ± 0.733
1.195AspTyr: 1.195 ± 1.014
0.0AspXaa: 0.0 ± 0.0
Glu
3.584GluAla: 3.584 ± 0.971
1.195GluCys: 1.195 ± 0.574
0.597GluAsp: 0.597 ± 0.414
2.987GluGlu: 2.987 ± 1.14
1.195GluPhe: 1.195 ± 1.014
3.584GluGly: 3.584 ± 0.971
2.389GluHis: 2.389 ± 0.762
0.597GluIle: 0.597 ± 0.507
2.389GluLys: 2.389 ± 0.658
4.182GluLeu: 4.182 ± 0.43
0.597GluMet: 0.597 ± 0.678
1.195GluAsn: 1.195 ± 0.733
2.389GluPro: 2.389 ± 1.278
1.792GluGln: 1.792 ± 0.614
4.182GluArg: 4.182 ± 0.571
1.195GluSer: 1.195 ± 0.574
1.792GluThr: 1.792 ± 1.063
3.584GluVal: 3.584 ± 0.263
1.195GluTrp: 1.195 ± 1.014
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.792PheAla: 1.792 ± 0.614
1.792PheCys: 1.792 ± 0.795
2.389PheAsp: 2.389 ± 0.762
0.597PheGlu: 0.597 ± 0.507
0.0PhePhe: 0.0 ± 0.0
0.597PheGly: 0.597 ± 0.678
2.987PheHis: 2.987 ± 1.14
3.584PheIle: 3.584 ± 0.263
1.792PheLys: 1.792 ± 1.521
1.792PheLeu: 1.792 ± 0.353
0.597PheMet: 0.597 ± 0.626
2.389PheAsn: 2.389 ± 1.844
1.195PhePro: 1.195 ± 0.381
2.389PheGln: 2.389 ± 1.147
3.584PheArg: 3.584 ± 0.787
2.389PheSer: 2.389 ± 0.975
1.792PheThr: 1.792 ± 1.185
1.195PheVal: 1.195 ± 0.733
0.597PheTrp: 0.597 ± 0.507
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.779GlyAla: 4.779 ± 1.79
0.0GlyCys: 0.0 ± 0.0
3.584GlyAsp: 3.584 ± 0.787
3.584GlyGlu: 3.584 ± 0.971
1.792GlyPhe: 1.792 ± 0.353
3.584GlyGly: 3.584 ± 1.8
2.389GlyHis: 2.389 ± 1.657
2.987GlyIle: 2.987 ± 1.121
2.389GlyLys: 2.389 ± 0.232
3.584GlyLeu: 3.584 ± 1.228
1.195GlyMet: 1.195 ± 0.918
1.792GlyAsn: 1.792 ± 2.033
4.182GlyPro: 4.182 ± 0.634
1.195GlyGln: 1.195 ± 0.574
5.974GlyArg: 5.974 ± 1.86
8.363GlySer: 8.363 ± 2.736
2.987GlyThr: 2.987 ± 2.626
5.974GlyVal: 5.974 ± 0.751
0.597GlyTrp: 0.597 ± 0.507
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.597HisAla: 0.597 ± 0.507
1.195HisCys: 1.195 ± 0.381
0.597HisAsp: 0.597 ± 0.414
2.389HisGlu: 2.389 ± 0.762
0.597HisPhe: 0.597 ± 0.414
2.987HisGly: 2.987 ± 1.367
0.597HisHis: 0.597 ± 0.414
1.195HisIle: 1.195 ± 0.829
1.195HisLys: 1.195 ± 0.381
3.584HisLeu: 3.584 ± 0.263
0.0HisMet: 0.0 ± 0.0
0.597HisAsn: 0.597 ± 0.414
1.792HisPro: 1.792 ± 1.521
1.195HisGln: 1.195 ± 0.381
2.389HisArg: 2.389 ± 0.975
2.389HisSer: 2.389 ± 1.048
2.987HisThr: 2.987 ± 1.964
2.389HisVal: 2.389 ± 0.975
1.195HisTrp: 1.195 ± 0.829
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.389IleAla: 2.389 ± 1.278
1.792IleCys: 1.792 ± 0.353
1.195IleAsp: 1.195 ± 0.829
3.584IleGlu: 3.584 ± 2.276
1.195IlePhe: 1.195 ± 1.355
1.792IleGly: 1.792 ± 1.243
0.597IleHis: 0.597 ± 0.507
1.195IleIle: 1.195 ± 1.014
1.195IleLys: 1.195 ± 0.381
1.792IleLeu: 1.792 ± 1.243
1.195IleMet: 1.195 ± 0.829
0.597IleAsn: 0.597 ± 0.678
1.792IlePro: 1.792 ± 0.795
1.195IleGln: 1.195 ± 1.355
2.987IleArg: 2.987 ± 0.571
3.584IleSer: 3.584 ± 0.263
1.792IleThr: 1.792 ± 2.033
4.182IleVal: 4.182 ± 0.966
0.597IleTrp: 0.597 ± 0.507
1.792IleTyr: 1.792 ± 1.063
0.0IleXaa: 0.0 ± 0.0
Lys
2.389LysAla: 2.389 ± 1.011
0.597LysCys: 0.597 ± 0.414
1.792LysAsp: 1.792 ± 0.353
1.792LysGlu: 1.792 ± 0.353
1.792LysPhe: 1.792 ± 1.063
0.597LysGly: 0.597 ± 0.507
0.0LysHis: 0.0 ± 0.0
1.195LysIle: 1.195 ± 1.355
0.0LysLys: 0.0 ± 0.0
4.779LysLeu: 4.779 ± 0.512
0.0LysMet: 0.0 ± 0.0
1.195LysAsn: 1.195 ± 0.574
3.584LysPro: 3.584 ± 0.263
2.987LysGln: 2.987 ± 1.775
3.584LysArg: 3.584 ± 2.126
1.792LysSer: 1.792 ± 0.795
1.792LysThr: 1.792 ± 0.614
5.376LysVal: 5.376 ± 1.781
0.597LysTrp: 0.597 ± 0.414
0.597LysTyr: 0.597 ± 0.507
0.0LysXaa: 0.0 ± 0.0
Leu
10.155LeuAla: 10.155 ± 0.611
2.389LeuCys: 2.389 ± 0.762
4.779LeuAsp: 4.779 ± 0.612
2.987LeuGlu: 2.987 ± 1.074
1.195LeuPhe: 1.195 ± 0.574
7.766LeuGly: 7.766 ± 2.42
2.389LeuHis: 2.389 ± 0.975
2.987LeuIle: 2.987 ± 0.282
1.195LeuLys: 1.195 ± 1.014
6.571LeuLeu: 6.571 ± 1.3
1.792LeuMet: 1.792 ± 0.736
2.987LeuAsn: 2.987 ± 0.282
10.155LeuPro: 10.155 ± 2.802
4.182LeuGln: 4.182 ± 2.068
8.363LeuArg: 8.363 ± 1.974
9.558LeuSer: 9.558 ± 1.493
3.584LeuThr: 3.584 ± 1.228
7.766LeuVal: 7.766 ± 0.878
1.195LeuTrp: 1.195 ± 0.574
2.987LeuTyr: 2.987 ± 0.806
0.0LeuXaa: 0.0 ± 0.0
Met
3.584MetAla: 3.584 ± 0.787
1.195MetCys: 1.195 ± 0.829
0.0MetAsp: 0.0 ± 0.0
0.597MetGlu: 0.597 ± 0.678
1.195MetPhe: 1.195 ± 0.381
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.597MetIle: 0.597 ± 0.678
0.597MetLys: 0.597 ± 0.678
1.792MetLeu: 1.792 ± 0.614
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.597MetGln: 0.597 ± 0.678
0.0MetArg: 0.0 ± 0.0
0.597MetSer: 0.597 ± 0.414
3.584MetThr: 3.584 ± 0.705
0.597MetVal: 0.597 ± 0.507
0.0MetTrp: 0.0 ± 0.0
0.597MetTyr: 0.597 ± 0.414
0.0MetXaa: 0.0 ± 0.0
Asn
2.389AsnAla: 2.389 ± 1.844
0.597AsnCys: 0.597 ± 0.414
1.195AsnAsp: 1.195 ± 0.829
0.597AsnGlu: 0.597 ± 0.414
3.584AsnPhe: 3.584 ± 1.671
3.584AsnGly: 3.584 ± 1.471
0.597AsnHis: 0.597 ± 0.507
1.195AsnIle: 1.195 ± 0.381
0.0AsnLys: 0.0 ± 0.0
2.389AsnLeu: 2.389 ± 0.762
0.597AsnMet: 0.597 ± 0.414
0.597AsnAsn: 0.597 ± 0.678
2.987AsnPro: 2.987 ± 1.253
2.389AsnGln: 2.389 ± 0.232
2.389AsnArg: 2.389 ± 0.232
1.792AsnSer: 1.792 ± 0.736
2.389AsnThr: 2.389 ± 1.048
1.195AsnVal: 1.195 ± 0.574
0.0AsnTrp: 0.0 ± 0.0
0.597AsnTyr: 0.597 ± 0.678
0.0AsnXaa: 0.0 ± 0.0
Pro
5.376ProAla: 5.376 ± 0.876
0.597ProCys: 0.597 ± 0.414
5.974ProAsp: 5.974 ± 0.317
1.195ProGlu: 1.195 ± 1.014
2.389ProPhe: 2.389 ± 0.232
5.376ProGly: 5.376 ± 2.208
2.987ProHis: 2.987 ± 1.367
2.987ProIle: 2.987 ± 1.14
1.792ProLys: 1.792 ± 1.063
8.363ProLeu: 8.363 ± 1.141
0.0ProMet: 0.0 ± 0.0
2.987ProAsn: 2.987 ± 1.413
3.584ProPro: 3.584 ± 1.471
1.792ProGln: 1.792 ± 1.185
5.974ProArg: 5.974 ± 0.565
4.779ProSer: 4.779 ± 1.358
8.961ProThr: 8.961 ± 0.88
4.182ProVal: 4.182 ± 0.43
1.792ProTrp: 1.792 ± 0.795
1.792ProTyr: 1.792 ± 0.795
0.0ProXaa: 0.0 ± 0.0
Gln
4.182GlnAla: 4.182 ± 1.805
0.0GlnCys: 0.0 ± 0.0
2.987GlnAsp: 2.987 ± 1.755
2.389GlnGlu: 2.389 ± 0.232
0.597GlnPhe: 0.597 ± 0.414
4.182GlnGly: 4.182 ± 0.927
0.597GlnHis: 0.597 ± 0.507
2.389GlnIle: 2.389 ± 1.048
0.597GlnLys: 0.597 ± 0.678
4.182GlnLeu: 4.182 ± 1.293
1.792GlnMet: 1.792 ± 0.353
1.195GlnAsn: 1.195 ± 0.829
3.584GlnPro: 3.584 ± 0.263
2.987GlnGln: 2.987 ± 0.806
3.584GlnArg: 3.584 ± 0.971
1.195GlnSer: 1.195 ± 0.733
2.389GlnThr: 2.389 ± 1.011
2.389GlnVal: 2.389 ± 1.147
1.195GlnTrp: 1.195 ± 0.733
1.792GlnTyr: 1.792 ± 1.243
0.0GlnXaa: 0.0 ± 0.0
Arg
4.182ArgAla: 4.182 ± 1.293
1.195ArgCys: 1.195 ± 0.381
3.584ArgAsp: 3.584 ± 1.769
3.584ArgGlu: 3.584 ± 0.787
4.182ArgPhe: 4.182 ± 0.927
4.779ArgGly: 4.779 ± 1.951
1.792ArgHis: 1.792 ± 0.614
2.987ArgIle: 2.987 ± 0.806
5.376ArgLys: 5.376 ± 1.917
5.974ArgLeu: 5.974 ± 1.86
1.792ArgMet: 1.792 ± 0.353
2.987ArgAsn: 2.987 ± 0.934
7.168ArgPro: 7.168 ± 2.686
4.182ArgGln: 4.182 ± 0.571
8.961ArgArg: 8.961 ± 0.847
4.182ArgSer: 4.182 ± 0.966
4.779ArgThr: 4.779 ± 1.928
10.155ArgVal: 10.155 ± 3.336
0.0ArgTrp: 0.0 ± 0.0
1.792ArgTyr: 1.792 ± 0.736
0.0ArgXaa: 0.0 ± 0.0
Ser
5.376SerAla: 5.376 ± 2.648
2.389SerCys: 2.389 ± 0.762
2.987SerAsp: 2.987 ± 0.806
1.792SerGlu: 1.792 ± 0.353
1.195SerPhe: 1.195 ± 0.381
2.389SerGly: 2.389 ± 0.232
2.389SerHis: 2.389 ± 0.762
2.987SerIle: 2.987 ± 0.806
3.584SerLys: 3.584 ± 1.228
4.182SerLeu: 4.182 ± 0.634
1.195SerMet: 1.195 ± 0.381
3.584SerAsn: 3.584 ± 0.787
4.779SerPro: 4.779 ± 1.104
1.792SerGln: 1.792 ± 1.318
7.766SerArg: 7.766 ± 2.402
5.974SerSer: 5.974 ± 1.86
2.389SerThr: 2.389 ± 0.762
7.168SerVal: 7.168 ± 2.39
2.987SerTrp: 2.987 ± 1.367
2.987SerTyr: 2.987 ± 0.934
0.0SerXaa: 0.0 ± 0.0
Thr
7.766ThrAla: 7.766 ± 1.58
0.597ThrCys: 0.597 ± 0.507
4.779ThrAsp: 4.779 ± 2.059
2.987ThrGlu: 2.987 ± 1.074
1.792ThrPhe: 1.792 ± 0.795
4.182ThrGly: 4.182 ± 2.144
1.195ThrHis: 1.195 ± 0.381
2.987ThrIle: 2.987 ± 1.367
0.0ThrLys: 0.0 ± 0.0
8.363ThrLeu: 8.363 ± 1.235
0.0ThrMet: 0.0 ± 0.0
0.597ThrAsn: 0.597 ± 0.414
5.376ThrPro: 5.376 ± 0.973
1.792ThrGln: 1.792 ± 1.318
5.376ThrArg: 5.376 ± 0.973
5.376ThrSer: 5.376 ± 0.876
5.376ThrThr: 5.376 ± 1.448
4.182ThrVal: 4.182 ± 1.354
1.792ThrTrp: 1.792 ± 1.521
1.792ThrTyr: 1.792 ± 1.243
0.0ThrXaa: 0.0 ± 0.0
Val
8.961ValAla: 8.961 ± 2.555
2.987ValCys: 2.987 ± 0.934
7.168ValAsp: 7.168 ± 2.153
1.792ValGlu: 1.792 ± 0.614
1.195ValPhe: 1.195 ± 0.381
2.987ValGly: 2.987 ± 1.413
3.584ValHis: 3.584 ± 0.787
1.792ValIle: 1.792 ± 1.063
5.376ValLys: 5.376 ± 1.058
11.35ValLeu: 11.35 ± 1.795
1.195ValMet: 1.195 ± 0.733
1.792ValAsn: 1.792 ± 0.736
5.376ValPro: 5.376 ± 1.058
2.389ValGln: 2.389 ± 1.011
2.987ValArg: 2.987 ± 0.571
7.766ValSer: 7.766 ± 0.979
6.571ValThr: 6.571 ± 0.833
4.182ValVal: 4.182 ± 1.293
0.597ValTrp: 0.597 ± 0.678
1.792ValTyr: 1.792 ± 0.614
0.0ValXaa: 0.0 ± 0.0
Trp
1.195TrpAla: 1.195 ± 0.381
0.597TrpCys: 0.597 ± 0.414
1.792TrpAsp: 1.792 ± 0.795
3.584TrpGlu: 3.584 ± 0.705
1.195TrpPhe: 1.195 ± 0.381
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.195TrpLys: 1.195 ± 1.014
1.792TrpLeu: 1.792 ± 0.795
0.0TrpMet: 0.0 ± 0.0
1.195TrpAsn: 1.195 ± 0.574
0.0TrpPro: 0.0 ± 0.0
0.597TrpGln: 0.597 ± 0.507
0.597TrpArg: 0.597 ± 0.507
0.597TrpSer: 0.597 ± 0.507
0.597TrpThr: 0.597 ± 0.414
1.792TrpVal: 1.792 ± 0.353
0.597TrpTrp: 0.597 ± 0.507
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.792TyrAsp: 1.792 ± 0.614
1.195TyrGlu: 1.195 ± 0.829
0.0TyrPhe: 0.0 ± 0.0
1.195TyrGly: 1.195 ± 0.381
0.597TyrHis: 0.597 ± 0.414
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
4.779TyrLeu: 4.779 ± 1.8
0.597TyrMet: 0.597 ± 0.507
0.0TyrAsn: 0.0 ± 0.0
2.389TyrPro: 2.389 ± 0.232
2.389TyrGln: 2.389 ± 0.232
2.389TyrArg: 2.389 ± 1.048
0.597TyrSer: 0.597 ± 0.507
1.195TyrThr: 1.195 ± 0.574
2.987TyrVal: 2.987 ± 0.806
0.0TyrTrp: 0.0 ± 0.0
0.597TyrTyr: 0.597 ± 0.678
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1675 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski