Cosavirus A (isolate Human/Pakistan/0553/-) (HCoSV-A)

Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Cosavirus; Cosavirus A; Human cosavirus A

Average proteome isoelectric point is 5.95

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>sp|B8XTP8|POLG_COSAA Genome polyprotein OS=Cosavirus A (isolate Human/Pakistan/0553/-) OX=1554483 PE=3 SV=1
MM1 pKa = 7.44GANNSKK7 pKa = 10.69EE8 pKa = 4.34SVSSNGNEE16 pKa = 3.66GTIVNNFYY24 pKa = 11.14SNQYY28 pKa = 8.31YY29 pKa = 11.04ASIDD33 pKa = 3.3ASAQGVGTSTTPEE46 pKa = 3.87NGNVSGFLGLAGSAFNALSLLASPRR71 pKa = 11.84TEE73 pKa = 3.63TGMMMEE79 pKa = 4.75DD80 pKa = 2.88RR81 pKa = 11.84VLSRR85 pKa = 11.84TAGNTSVNSQAAEE98 pKa = 4.24GVLQAYY104 pKa = 7.31GTEE107 pKa = 4.25TDD109 pKa = 3.84SNSPTSCGDD118 pKa = 3.57DD119 pKa = 3.6PSKK122 pKa = 10.45GTHH125 pKa = 4.9ATDD128 pKa = 3.13RR129 pKa = 11.84AFVIQLLPWKK139 pKa = 8.73QTTNSYY145 pKa = 8.9FAQWVRR151 pKa = 11.84LTQKK155 pKa = 10.66LSNNLHH161 pKa = 5.91GNVMAKK167 pKa = 10.11NIKK170 pKa = 9.11SHH172 pKa = 6.68AFAKK176 pKa = 10.1MGFEE180 pKa = 5.1VMLQANTSPFHH191 pKa = 6.57NGILGLFLVPEE202 pKa = 4.83FVRR205 pKa = 11.84KK206 pKa = 10.36GEE208 pKa = 4.24ITDD211 pKa = 3.23EE212 pKa = 4.61WIDD215 pKa = 3.78LTPTSSLVSNTEE227 pKa = 3.76LYY229 pKa = 10.78NPQTYY234 pKa = 11.29ANFPFDD240 pKa = 3.86AKK242 pKa = 10.88HH243 pKa = 6.23SFDD246 pKa = 4.11YY247 pKa = 11.37SDD249 pKa = 3.24ITPEE253 pKa = 3.49QFMIFPHH260 pKa = 5.9QLINPKK266 pKa = 8.59DD267 pKa = 3.78TNVATVRR274 pKa = 11.84VPYY277 pKa = 10.58INIAPTNDD285 pKa = 3.49TTVHH289 pKa = 5.1TVWTAVVMVLVPLNFSSGASPTVSLTLTITPINSVFNGLHH329 pKa = 5.86HH330 pKa = 6.79TAQGPIPVRR339 pKa = 11.84PFHH342 pKa = 6.67NFQQFSTTVPLRR354 pKa = 11.84TEE356 pKa = 3.73PCYY359 pKa = 11.16GMTVTPPVDD368 pKa = 3.94YY369 pKa = 9.95MPLPITDD376 pKa = 4.12LVEE379 pKa = 4.06LAKK382 pKa = 10.79VPSFVTVANSDD393 pKa = 3.71TTSEE397 pKa = 3.82RR398 pKa = 11.84SFPYY402 pKa = 9.94FSVSNTEE409 pKa = 3.54QGRR412 pKa = 11.84NLFKK416 pKa = 11.01SSVVLSDD423 pKa = 3.46LHH425 pKa = 5.74YY426 pKa = 10.95QHH428 pKa = 6.8TLVANLARR436 pKa = 11.84YY437 pKa = 7.6FCNYY441 pKa = 9.54RR442 pKa = 11.84GSLQFDD448 pKa = 4.67FIAATTAMTRR458 pKa = 11.84GKK460 pKa = 10.5LLISYY465 pKa = 7.5TPPGAGEE472 pKa = 4.02PQSIDD477 pKa = 3.18QAMMGTYY484 pKa = 10.25AIWDD488 pKa = 4.09LGLQSTFNFVVPFISASDD506 pKa = 3.61FRR508 pKa = 11.84FNTSSVSNALNSDD521 pKa = 2.97GWITVWLMNPLTYY534 pKa = 10.18PPSTPPTQQILMLMSAGSDD553 pKa = 3.22FSYY556 pKa = 10.79RR557 pKa = 11.84LPISPGFAEE566 pKa = 5.23GEE568 pKa = 4.38TSEE571 pKa = 5.48HH572 pKa = 6.27PMDD575 pKa = 3.93NAEE578 pKa = 4.83CGKK581 pKa = 10.05IDD583 pKa = 5.15DD584 pKa = 4.9KK585 pKa = 11.5DD586 pKa = 3.69AGMFSGHH593 pKa = 5.75SVGLPTPHH601 pKa = 6.9TSTSFFYY608 pKa = 10.74DD609 pKa = 3.36RR610 pKa = 11.84YY611 pKa = 9.76RR612 pKa = 11.84FVGIVKK618 pKa = 10.1SVVNNTPKK626 pKa = 10.36PVNIYY631 pKa = 11.04DD632 pKa = 3.67DD633 pKa = 3.59TGKK636 pKa = 10.62VKK638 pKa = 10.49NLQQVFPTSDD648 pKa = 2.89TLLPHH653 pKa = 6.77SLMSLSPCASVCGQPISSFLFAQRR677 pKa = 11.84ANPKK681 pKa = 8.58KK682 pKa = 8.68TLKK685 pKa = 10.38LRR687 pKa = 11.84SGDD690 pKa = 3.4EE691 pKa = 3.79FLYY694 pKa = 10.28RR695 pKa = 11.84CCPFSYY701 pKa = 10.0IKK703 pKa = 10.45CDD705 pKa = 3.46LEE707 pKa = 4.38FTVVPPANSTRR718 pKa = 11.84DD719 pKa = 4.15YY720 pKa = 10.49IVHH723 pKa = 7.25WYY725 pKa = 9.12PPGATLDD732 pKa = 3.7AGEE735 pKa = 4.29VAVGNTSGSNGFDD748 pKa = 3.7DD749 pKa = 4.75NGMNAGSSLFSYY761 pKa = 10.83NPTFHH766 pKa = 6.96ARR768 pKa = 11.84APSKK772 pKa = 10.63VSAVIPFCLPVSLLPLYY789 pKa = 10.78FDD791 pKa = 4.83GFPDD795 pKa = 3.66YY796 pKa = 10.84STTKK800 pKa = 10.49GMYY803 pKa = 8.88GCSPSFSFGTIYY815 pKa = 10.27IEE817 pKa = 4.68SGLQEE822 pKa = 4.33TYY824 pKa = 10.68SVYY827 pKa = 10.31IRR829 pKa = 11.84YY830 pKa = 9.56KK831 pKa = 10.37DD832 pKa = 3.69FKK834 pKa = 10.79GYY836 pKa = 10.87APRR839 pKa = 11.84PLIRR843 pKa = 11.84TPHH846 pKa = 5.5IRR848 pKa = 11.84LSEE851 pKa = 3.9RR852 pKa = 11.84ARR854 pKa = 11.84YY855 pKa = 9.48IMADD859 pKa = 3.2SVLPRR864 pKa = 11.84PLTRR868 pKa = 11.84AEE870 pKa = 3.73RR871 pKa = 11.84DD872 pKa = 3.47VARR875 pKa = 11.84DD876 pKa = 3.43LLLIAGDD883 pKa = 3.76IEE885 pKa = 5.27SNPGPAFNPEE895 pKa = 4.01YY896 pKa = 9.13TAHH899 pKa = 6.57GPVTEE904 pKa = 5.45LIQLARR910 pKa = 11.84KK911 pKa = 9.31PEE913 pKa = 4.09TVDD916 pKa = 3.04NVNRR920 pKa = 11.84LLTTLNTLMAKK931 pKa = 9.25WNNLKK936 pKa = 9.28DD937 pKa = 3.81TVTDD941 pKa = 3.8AVFLRR946 pKa = 11.84DD947 pKa = 4.01MVCLLVKK954 pKa = 9.69LTSLMYY960 pKa = 10.23LVHH963 pKa = 6.11GQGPGAYY970 pKa = 8.82FAAASILLADD980 pKa = 5.8GITFFDD986 pKa = 3.76WYY988 pKa = 10.08EE989 pKa = 3.97KK990 pKa = 10.59IKK992 pKa = 10.86IFMARR997 pKa = 11.84KK998 pKa = 9.43LRR1000 pKa = 11.84VSPPFFPAAQGPDD1013 pKa = 3.01LRR1015 pKa = 11.84DD1016 pKa = 3.1FVTFFNAARR1025 pKa = 11.84GAQWMIDD1032 pKa = 3.6SLKK1035 pKa = 11.18SLITCIKK1042 pKa = 9.21QWLEE1046 pKa = 3.8LEE1048 pKa = 4.4EE1049 pKa = 4.2EE1050 pKa = 4.33NEE1052 pKa = 4.05AVQLEE1057 pKa = 4.41KK1058 pKa = 10.56MLIDD1062 pKa = 4.15SPRR1065 pKa = 11.84HH1066 pKa = 5.01CKK1068 pKa = 10.32AINDD1072 pKa = 3.9YY1073 pKa = 11.24NRR1075 pKa = 11.84GDD1077 pKa = 3.56SFQRR1081 pKa = 11.84PTNSFEE1087 pKa = 4.03FMDD1090 pKa = 4.42RR1091 pKa = 11.84LVEE1094 pKa = 4.14CATKK1098 pKa = 10.46LGKK1101 pKa = 9.82VQIATYY1107 pKa = 9.9FRR1109 pKa = 11.84NFTTADD1115 pKa = 3.42SDD1117 pKa = 3.76TSRR1120 pKa = 11.84PEE1122 pKa = 3.56PVVVVLRR1129 pKa = 11.84GKK1131 pKa = 9.88PGVGKK1136 pKa = 10.22SAAATVMAAAVSKK1149 pKa = 10.64LLVGSQSVYY1158 pKa = 10.15TLSPDD1163 pKa = 3.6TEE1165 pKa = 4.51HH1166 pKa = 6.78MDD1168 pKa = 3.77GYY1170 pKa = 10.59HH1171 pKa = 5.7GQFVTLMDD1179 pKa = 5.37DD1180 pKa = 4.56LGQNPDD1186 pKa = 3.91GEE1188 pKa = 4.55DD1189 pKa = 3.66FRR1191 pKa = 11.84CFCQMVSCAQYY1202 pKa = 10.05RR1203 pKa = 11.84PAMADD1208 pKa = 3.39LKK1210 pKa = 11.27DD1211 pKa = 3.54KK1212 pKa = 11.42GILFTSRR1219 pKa = 11.84LLIATTNLPDD1229 pKa = 4.43FNPVTISDD1237 pKa = 3.62PRR1239 pKa = 11.84ALDD1242 pKa = 3.27RR1243 pKa = 11.84RR1244 pKa = 11.84ITFDD1248 pKa = 3.01ILVTPGSAATKK1259 pKa = 10.28NGKK1262 pKa = 9.44LDD1264 pKa = 3.43LAAALKK1270 pKa = 10.15PDD1272 pKa = 3.77GPGEE1276 pKa = 4.0HH1277 pKa = 7.72PYY1279 pKa = 10.74TSDD1282 pKa = 4.19CPILHH1287 pKa = 5.53TTGLLLKK1294 pKa = 10.27NLRR1297 pKa = 11.84NNQTMNLKK1305 pKa = 10.45DD1306 pKa = 4.09LVDD1309 pKa = 4.5MIVKK1313 pKa = 10.32RR1314 pKa = 11.84IKK1316 pKa = 10.17HH1317 pKa = 5.4KK1318 pKa = 11.1KK1319 pKa = 8.58EE1320 pKa = 3.62VGNMLDD1326 pKa = 3.38SLVAQGPTMIVGYY1339 pKa = 8.73TKK1341 pKa = 10.88DD1342 pKa = 3.7DD1343 pKa = 3.99DD1344 pKa = 5.14GIAIVDD1350 pKa = 5.04CLEE1353 pKa = 3.81EE1354 pKa = 4.0WNKK1357 pKa = 10.37IKK1359 pKa = 10.58DD1360 pKa = 3.68KK1361 pKa = 10.93KK1362 pKa = 10.54KK1363 pKa = 10.12KK1364 pKa = 9.72QLALEE1369 pKa = 4.3MVAQEE1374 pKa = 4.87LKK1376 pKa = 10.73DD1377 pKa = 3.14KK1378 pKa = 11.17HH1379 pKa = 6.42EE1380 pKa = 4.12EE1381 pKa = 3.92HH1382 pKa = 6.98KK1383 pKa = 10.77GTIKK1387 pKa = 10.3LLKK1390 pKa = 9.96MFVTGLGVVAAVAGAYY1406 pKa = 8.54ATMKK1410 pKa = 10.53YY1411 pKa = 7.49FTKK1414 pKa = 10.49DD1415 pKa = 2.9KK1416 pKa = 10.42PKK1418 pKa = 10.67EE1419 pKa = 4.01EE1420 pKa = 4.18EE1421 pKa = 4.11EE1422 pKa = 4.06EE1423 pKa = 4.27PEE1425 pKa = 3.95EE1426 pKa = 4.18KK1427 pKa = 10.23KK1428 pKa = 10.62EE1429 pKa = 4.15KK1430 pKa = 9.4KK1431 pKa = 9.08TEE1433 pKa = 3.98EE1434 pKa = 4.23SKK1436 pKa = 10.93EE1437 pKa = 3.66AAGPYY1442 pKa = 9.7NGPTKK1447 pKa = 10.73KK1448 pKa = 10.18EE1449 pKa = 3.75IKK1451 pKa = 8.92TLKK1454 pKa = 10.52LKK1456 pKa = 10.54AQSPLMDD1463 pKa = 3.75MEE1465 pKa = 5.07KK1466 pKa = 10.51KK1467 pKa = 9.74IAQNVMPFQIFYY1479 pKa = 10.15NGKK1482 pKa = 10.16RR1483 pKa = 11.84YY1484 pKa = 7.02TQSCLAIGKK1493 pKa = 9.4RR1494 pKa = 11.84VILVNKK1500 pKa = 9.56HH1501 pKa = 5.21AFEE1504 pKa = 4.28SVEE1507 pKa = 4.01HH1508 pKa = 6.54KK1509 pKa = 10.72FVVDD1513 pKa = 3.56QKK1515 pKa = 11.3EE1516 pKa = 4.1YY1517 pKa = 10.4TLDD1520 pKa = 3.27QVTAISLDD1528 pKa = 3.8CGSGVTDD1535 pKa = 3.4VCAVCLPPGPDD1546 pKa = 3.05FKK1548 pKa = 11.19SIKK1551 pKa = 10.01KK1552 pKa = 9.85HH1553 pKa = 5.15FLPFNTTMFPGTRR1566 pKa = 11.84LTILSNDD1573 pKa = 3.97HH1574 pKa = 6.4YY1575 pKa = 10.84PMSRR1579 pKa = 11.84EE1580 pKa = 3.68GSFLRR1585 pKa = 11.84FEE1587 pKa = 5.19DD1588 pKa = 4.27EE1589 pKa = 4.2VPTNVGNMPFVMLYY1603 pKa = 10.63KK1604 pKa = 8.86STSYY1608 pKa = 10.94FGMCGSVVCSRR1619 pKa = 11.84FVDD1622 pKa = 3.63GGGIIGMHH1630 pKa = 6.46CAGGGGVSVGTRR1642 pKa = 11.84LTARR1646 pKa = 11.84MIEE1649 pKa = 4.23SVFDD1653 pKa = 3.36YY1654 pKa = 9.25FYY1656 pKa = 10.86PPVAQGIIEE1665 pKa = 4.1NTEE1668 pKa = 3.62TGPRR1672 pKa = 11.84VHH1674 pKa = 6.75VPRR1677 pKa = 11.84TSKK1680 pKa = 10.76LKK1682 pKa = 9.56RR1683 pKa = 11.84TNATYY1688 pKa = 8.91PATEE1692 pKa = 4.33KK1693 pKa = 10.78YY1694 pKa = 10.62GPAALSRR1701 pKa = 11.84YY1702 pKa = 9.53DD1703 pKa = 3.27PRR1705 pKa = 11.84LNEE1708 pKa = 3.99GVNLDD1713 pKa = 3.47EE1714 pKa = 5.67VIFSKK1719 pKa = 8.98HH1720 pKa = 4.04TQNTLVEE1727 pKa = 4.39KK1728 pKa = 10.9GSTFRR1733 pKa = 11.84SALDD1737 pKa = 3.46MAAEE1741 pKa = 4.29IYY1743 pKa = 10.66GEE1745 pKa = 4.14KK1746 pKa = 10.52FRR1748 pKa = 11.84GNDD1751 pKa = 3.59FSPLSVEE1758 pKa = 4.35DD1759 pKa = 5.12AILGIPGLDD1768 pKa = 2.74RR1769 pKa = 11.84LDD1771 pKa = 4.44PNTASGLPYY1780 pKa = 10.17TKK1782 pKa = 9.69TRR1784 pKa = 11.84RR1785 pKa = 11.84QMIDD1789 pKa = 3.19FNTGQILDD1797 pKa = 4.04DD1798 pKa = 3.77TLKK1801 pKa = 10.81CRR1803 pKa = 11.84LGQWLAGRR1811 pKa = 11.84PPQEE1815 pKa = 3.37VHH1817 pKa = 5.59YY1818 pKa = 9.24QTFLKK1823 pKa = 10.93DD1824 pKa = 3.64EE1825 pKa = 4.03IRR1827 pKa = 11.84PIEE1830 pKa = 4.16KK1831 pKa = 10.27VKK1833 pKa = 10.79AGKK1836 pKa = 7.9TRR1838 pKa = 11.84IIDD1841 pKa = 3.9VPPLDD1846 pKa = 3.69HH1847 pKa = 7.18VIAFRR1852 pKa = 11.84MLFGRR1857 pKa = 11.84FIAHH1861 pKa = 5.05YY1862 pKa = 9.5HH1863 pKa = 5.98LNFGFKK1869 pKa = 9.07TGSAIGCDD1877 pKa = 3.86PDD1879 pKa = 3.85VAWASFGFEE1888 pKa = 3.95LSGFPYY1894 pKa = 10.39LYY1896 pKa = 11.01DD1897 pKa = 3.56FDD1899 pKa = 4.97YY1900 pKa = 11.67SNFDD1904 pKa = 3.55ASHH1907 pKa = 5.52STSIFEE1913 pKa = 4.13ILEE1916 pKa = 3.91QKK1918 pKa = 10.39FFSPEE1923 pKa = 3.61LGFDD1927 pKa = 3.78PRR1929 pKa = 11.84CSLLLKK1935 pKa = 10.33SLAVSTHH1942 pKa = 5.95CYY1944 pKa = 8.41EE1945 pKa = 4.26NKK1947 pKa = 9.91RR1948 pKa = 11.84LQIAGGLPSGTAGTSVLNTVINNIIFHH1975 pKa = 6.35GALYY1979 pKa = 8.48HH1980 pKa = 6.61TYY1982 pKa = 10.79TNFEE1986 pKa = 4.04RR1987 pKa = 11.84DD1988 pKa = 4.55DD1989 pKa = 4.13ISMLAYY1995 pKa = 10.42GDD1997 pKa = 4.92DD1998 pKa = 3.15IVVASKK2004 pKa = 11.22FEE2006 pKa = 4.49LDD2008 pKa = 3.44LVMVKK2013 pKa = 10.9AFMNRR2018 pKa = 11.84IGYY2021 pKa = 9.68KK2022 pKa = 8.63ITPADD2027 pKa = 3.51KK2028 pKa = 10.75SDD2030 pKa = 3.46EE2031 pKa = 4.03FRR2033 pKa = 11.84PKK2035 pKa = 10.81CMDD2038 pKa = 5.12DD2039 pKa = 2.85ICFLKK2044 pKa = 10.63RR2045 pKa = 11.84RR2046 pKa = 11.84FVKK2049 pKa = 10.62VAGVWAPVMEE2059 pKa = 4.42TEE2061 pKa = 4.36NLEE2064 pKa = 5.53AMLSWYY2070 pKa = 10.36KK2071 pKa = 10.66PGTLNEE2077 pKa = 4.2KK2078 pKa = 9.44LQSVSRR2084 pKa = 11.84LAHH2087 pKa = 5.46FSGRR2091 pKa = 11.84DD2092 pKa = 3.57VYY2094 pKa = 11.78DD2095 pKa = 3.5HH2096 pKa = 6.89LFKK2099 pKa = 10.98PFIRR2103 pKa = 11.84DD2104 pKa = 3.53GFDD2107 pKa = 3.03VTPWKK2112 pKa = 10.04QLHH2115 pKa = 6.23LEE2117 pKa = 4.12WLNKK2121 pKa = 10.04LSAA2124 pKa = 4.12

Molecular weight:
235.74 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>sp|B8XTP8|POLG_COSAA Genome polyprotein OS=Cosavirus A (isolate Human/Pakistan/0553/-) OX=1554483 PE=3 SV=1
MM1 pKa = 7.44GANNSKK7 pKa = 10.69EE8 pKa = 4.34SVSSNGNEE16 pKa = 3.66GTIVNNFYY24 pKa = 11.14SNQYY28 pKa = 8.31YY29 pKa = 11.04ASIDD33 pKa = 3.3ASAQGVGTSTTPEE46 pKa = 3.87NGNVSGFLGLAGSAFNALSLLASPRR71 pKa = 11.84TEE73 pKa = 3.63TGMMMEE79 pKa = 4.75DD80 pKa = 2.88RR81 pKa = 11.84VLSRR85 pKa = 11.84TAGNTSVNSQAAEE98 pKa = 4.24GVLQAYY104 pKa = 7.31GTEE107 pKa = 4.25TDD109 pKa = 3.84SNSPTSCGDD118 pKa = 3.57DD119 pKa = 3.6PSKK122 pKa = 10.45GTHH125 pKa = 4.9ATDD128 pKa = 3.13RR129 pKa = 11.84AFVIQLLPWKK139 pKa = 8.73QTTNSYY145 pKa = 8.9FAQWVRR151 pKa = 11.84LTQKK155 pKa = 10.66LSNNLHH161 pKa = 5.91GNVMAKK167 pKa = 10.11NIKK170 pKa = 9.11SHH172 pKa = 6.68AFAKK176 pKa = 10.1MGFEE180 pKa = 5.1VMLQANTSPFHH191 pKa = 6.57NGILGLFLVPEE202 pKa = 4.83FVRR205 pKa = 11.84KK206 pKa = 10.36GEE208 pKa = 4.24ITDD211 pKa = 3.23EE212 pKa = 4.61WIDD215 pKa = 3.78LTPTSSLVSNTEE227 pKa = 3.76LYY229 pKa = 10.78NPQTYY234 pKa = 11.29ANFPFDD240 pKa = 3.86AKK242 pKa = 10.88HH243 pKa = 6.23SFDD246 pKa = 4.11YY247 pKa = 11.37SDD249 pKa = 3.24ITPEE253 pKa = 3.49QFMIFPHH260 pKa = 5.9QLINPKK266 pKa = 8.59DD267 pKa = 3.78TNVATVRR274 pKa = 11.84VPYY277 pKa = 10.58INIAPTNDD285 pKa = 3.49TTVHH289 pKa = 5.1TVWTAVVMVLVPLNFSSGASPTVSLTLTITPINSVFNGLHH329 pKa = 5.86HH330 pKa = 6.79TAQGPIPVRR339 pKa = 11.84PFHH342 pKa = 6.67NFQQFSTTVPLRR354 pKa = 11.84TEE356 pKa = 3.73PCYY359 pKa = 11.16GMTVTPPVDD368 pKa = 3.94YY369 pKa = 9.95MPLPITDD376 pKa = 4.12LVEE379 pKa = 4.06LAKK382 pKa = 10.79VPSFVTVANSDD393 pKa = 3.71TTSEE397 pKa = 3.82RR398 pKa = 11.84SFPYY402 pKa = 9.94FSVSNTEE409 pKa = 3.54QGRR412 pKa = 11.84NLFKK416 pKa = 11.01SSVVLSDD423 pKa = 3.46LHH425 pKa = 5.74YY426 pKa = 10.95QHH428 pKa = 6.8TLVANLARR436 pKa = 11.84YY437 pKa = 7.6FCNYY441 pKa = 9.54RR442 pKa = 11.84GSLQFDD448 pKa = 4.67FIAATTAMTRR458 pKa = 11.84GKK460 pKa = 10.5LLISYY465 pKa = 7.5TPPGAGEE472 pKa = 4.02PQSIDD477 pKa = 3.18QAMMGTYY484 pKa = 10.25AIWDD488 pKa = 4.09LGLQSTFNFVVPFISASDD506 pKa = 3.61FRR508 pKa = 11.84FNTSSVSNALNSDD521 pKa = 2.97GWITVWLMNPLTYY534 pKa = 10.18PPSTPPTQQILMLMSAGSDD553 pKa = 3.22FSYY556 pKa = 10.79RR557 pKa = 11.84LPISPGFAEE566 pKa = 5.23GEE568 pKa = 4.38TSEE571 pKa = 5.48HH572 pKa = 6.27PMDD575 pKa = 3.93NAEE578 pKa = 4.83CGKK581 pKa = 10.05IDD583 pKa = 5.15DD584 pKa = 4.9KK585 pKa = 11.5DD586 pKa = 3.69AGMFSGHH593 pKa = 5.75SVGLPTPHH601 pKa = 6.9TSTSFFYY608 pKa = 10.74DD609 pKa = 3.36RR610 pKa = 11.84YY611 pKa = 9.76RR612 pKa = 11.84FVGIVKK618 pKa = 10.1SVVNNTPKK626 pKa = 10.36PVNIYY631 pKa = 11.04DD632 pKa = 3.67DD633 pKa = 3.59TGKK636 pKa = 10.62VKK638 pKa = 10.49NLQQVFPTSDD648 pKa = 2.89TLLPHH653 pKa = 6.77SLMSLSPCASVCGQPISSFLFAQRR677 pKa = 11.84ANPKK681 pKa = 8.58KK682 pKa = 8.68TLKK685 pKa = 10.38LRR687 pKa = 11.84SGDD690 pKa = 3.4EE691 pKa = 3.79FLYY694 pKa = 10.28RR695 pKa = 11.84CCPFSYY701 pKa = 10.0IKK703 pKa = 10.45CDD705 pKa = 3.46LEE707 pKa = 4.38FTVVPPANSTRR718 pKa = 11.84DD719 pKa = 4.15YY720 pKa = 10.49IVHH723 pKa = 7.25WYY725 pKa = 9.12PPGATLDD732 pKa = 3.7AGEE735 pKa = 4.29VAVGNTSGSNGFDD748 pKa = 3.7DD749 pKa = 4.75NGMNAGSSLFSYY761 pKa = 10.83NPTFHH766 pKa = 6.96ARR768 pKa = 11.84APSKK772 pKa = 10.63VSAVIPFCLPVSLLPLYY789 pKa = 10.78FDD791 pKa = 4.83GFPDD795 pKa = 3.66YY796 pKa = 10.84STTKK800 pKa = 10.49GMYY803 pKa = 8.88GCSPSFSFGTIYY815 pKa = 10.27IEE817 pKa = 4.68SGLQEE822 pKa = 4.33TYY824 pKa = 10.68SVYY827 pKa = 10.31IRR829 pKa = 11.84YY830 pKa = 9.56KK831 pKa = 10.37DD832 pKa = 3.69FKK834 pKa = 10.79GYY836 pKa = 10.87APRR839 pKa = 11.84PLIRR843 pKa = 11.84TPHH846 pKa = 5.5IRR848 pKa = 11.84LSEE851 pKa = 3.9RR852 pKa = 11.84ARR854 pKa = 11.84YY855 pKa = 9.48IMADD859 pKa = 3.2SVLPRR864 pKa = 11.84PLTRR868 pKa = 11.84AEE870 pKa = 3.73RR871 pKa = 11.84DD872 pKa = 3.47VARR875 pKa = 11.84DD876 pKa = 3.43LLLIAGDD883 pKa = 3.76IEE885 pKa = 5.27SNPGPAFNPEE895 pKa = 4.01YY896 pKa = 9.13TAHH899 pKa = 6.57GPVTEE904 pKa = 5.45LIQLARR910 pKa = 11.84KK911 pKa = 9.31PEE913 pKa = 4.09TVDD916 pKa = 3.04NVNRR920 pKa = 11.84LLTTLNTLMAKK931 pKa = 9.25WNNLKK936 pKa = 9.28DD937 pKa = 3.81TVTDD941 pKa = 3.8AVFLRR946 pKa = 11.84DD947 pKa = 4.01MVCLLVKK954 pKa = 9.69LTSLMYY960 pKa = 10.23LVHH963 pKa = 6.11GQGPGAYY970 pKa = 8.82FAAASILLADD980 pKa = 5.8GITFFDD986 pKa = 3.76WYY988 pKa = 10.08EE989 pKa = 3.97KK990 pKa = 10.59IKK992 pKa = 10.86IFMARR997 pKa = 11.84KK998 pKa = 9.43LRR1000 pKa = 11.84VSPPFFPAAQGPDD1013 pKa = 3.01LRR1015 pKa = 11.84DD1016 pKa = 3.1FVTFFNAARR1025 pKa = 11.84GAQWMIDD1032 pKa = 3.6SLKK1035 pKa = 11.18SLITCIKK1042 pKa = 9.21QWLEE1046 pKa = 3.8LEE1048 pKa = 4.4EE1049 pKa = 4.2EE1050 pKa = 4.33NEE1052 pKa = 4.05AVQLEE1057 pKa = 4.41KK1058 pKa = 10.56MLIDD1062 pKa = 4.15SPRR1065 pKa = 11.84HH1066 pKa = 5.01CKK1068 pKa = 10.32AINDD1072 pKa = 3.9YY1073 pKa = 11.24NRR1075 pKa = 11.84GDD1077 pKa = 3.56SFQRR1081 pKa = 11.84PTNSFEE1087 pKa = 4.03FMDD1090 pKa = 4.42RR1091 pKa = 11.84LVEE1094 pKa = 4.14CATKK1098 pKa = 10.46LGKK1101 pKa = 9.82VQIATYY1107 pKa = 9.9FRR1109 pKa = 11.84NFTTADD1115 pKa = 3.42SDD1117 pKa = 3.76TSRR1120 pKa = 11.84PEE1122 pKa = 3.56PVVVVLRR1129 pKa = 11.84GKK1131 pKa = 9.88PGVGKK1136 pKa = 10.22SAAATVMAAAVSKK1149 pKa = 10.64LLVGSQSVYY1158 pKa = 10.15TLSPDD1163 pKa = 3.6TEE1165 pKa = 4.51HH1166 pKa = 6.78MDD1168 pKa = 3.77GYY1170 pKa = 10.59HH1171 pKa = 5.7GQFVTLMDD1179 pKa = 5.37DD1180 pKa = 4.56LGQNPDD1186 pKa = 3.91GEE1188 pKa = 4.55DD1189 pKa = 3.66FRR1191 pKa = 11.84CFCQMVSCAQYY1202 pKa = 10.05RR1203 pKa = 11.84PAMADD1208 pKa = 3.39LKK1210 pKa = 11.27DD1211 pKa = 3.54KK1212 pKa = 11.42GILFTSRR1219 pKa = 11.84LLIATTNLPDD1229 pKa = 4.43FNPVTISDD1237 pKa = 3.62PRR1239 pKa = 11.84ALDD1242 pKa = 3.27RR1243 pKa = 11.84RR1244 pKa = 11.84ITFDD1248 pKa = 3.01ILVTPGSAATKK1259 pKa = 10.28NGKK1262 pKa = 9.44LDD1264 pKa = 3.43LAAALKK1270 pKa = 10.15PDD1272 pKa = 3.77GPGEE1276 pKa = 4.0HH1277 pKa = 7.72PYY1279 pKa = 10.74TSDD1282 pKa = 4.19CPILHH1287 pKa = 5.53TTGLLLKK1294 pKa = 10.27NLRR1297 pKa = 11.84NNQTMNLKK1305 pKa = 10.45DD1306 pKa = 4.09LVDD1309 pKa = 4.5MIVKK1313 pKa = 10.32RR1314 pKa = 11.84IKK1316 pKa = 10.17HH1317 pKa = 5.4KK1318 pKa = 11.1KK1319 pKa = 8.58EE1320 pKa = 3.62VGNMLDD1326 pKa = 3.38SLVAQGPTMIVGYY1339 pKa = 8.73TKK1341 pKa = 10.88DD1342 pKa = 3.7DD1343 pKa = 3.99DD1344 pKa = 5.14GIAIVDD1350 pKa = 5.04CLEE1353 pKa = 3.81EE1354 pKa = 4.0WNKK1357 pKa = 10.37IKK1359 pKa = 10.58DD1360 pKa = 3.68KK1361 pKa = 10.93KK1362 pKa = 10.54KK1363 pKa = 10.12KK1364 pKa = 9.72QLALEE1369 pKa = 4.3MVAQEE1374 pKa = 4.87LKK1376 pKa = 10.73DD1377 pKa = 3.14KK1378 pKa = 11.17HH1379 pKa = 6.42EE1380 pKa = 4.12EE1381 pKa = 3.92HH1382 pKa = 6.98KK1383 pKa = 10.77GTIKK1387 pKa = 10.3LLKK1390 pKa = 9.96MFVTGLGVVAAVAGAYY1406 pKa = 8.54ATMKK1410 pKa = 10.53YY1411 pKa = 7.49FTKK1414 pKa = 10.49DD1415 pKa = 2.9KK1416 pKa = 10.42PKK1418 pKa = 10.67EE1419 pKa = 4.01EE1420 pKa = 4.18EE1421 pKa = 4.11EE1422 pKa = 4.06EE1423 pKa = 4.27PEE1425 pKa = 3.95EE1426 pKa = 4.18KK1427 pKa = 10.23KK1428 pKa = 10.62EE1429 pKa = 4.15KK1430 pKa = 9.4KK1431 pKa = 9.08TEE1433 pKa = 3.98EE1434 pKa = 4.23SKK1436 pKa = 10.93EE1437 pKa = 3.66AAGPYY1442 pKa = 9.7NGPTKK1447 pKa = 10.73KK1448 pKa = 10.18EE1449 pKa = 3.75IKK1451 pKa = 8.92TLKK1454 pKa = 10.52LKK1456 pKa = 10.54AQSPLMDD1463 pKa = 3.75MEE1465 pKa = 5.07KK1466 pKa = 10.51KK1467 pKa = 9.74IAQNVMPFQIFYY1479 pKa = 10.15NGKK1482 pKa = 10.16RR1483 pKa = 11.84YY1484 pKa = 7.02TQSCLAIGKK1493 pKa = 9.4RR1494 pKa = 11.84VILVNKK1500 pKa = 9.56HH1501 pKa = 5.21AFEE1504 pKa = 4.28SVEE1507 pKa = 4.01HH1508 pKa = 6.54KK1509 pKa = 10.72FVVDD1513 pKa = 3.56QKK1515 pKa = 11.3EE1516 pKa = 4.1YY1517 pKa = 10.4TLDD1520 pKa = 3.27QVTAISLDD1528 pKa = 3.8CGSGVTDD1535 pKa = 3.4VCAVCLPPGPDD1546 pKa = 3.05FKK1548 pKa = 11.19SIKK1551 pKa = 10.01KK1552 pKa = 9.85HH1553 pKa = 5.15FLPFNTTMFPGTRR1566 pKa = 11.84LTILSNDD1573 pKa = 3.97HH1574 pKa = 6.4YY1575 pKa = 10.84PMSRR1579 pKa = 11.84EE1580 pKa = 3.68GSFLRR1585 pKa = 11.84FEE1587 pKa = 5.19DD1588 pKa = 4.27EE1589 pKa = 4.2VPTNVGNMPFVMLYY1603 pKa = 10.63KK1604 pKa = 8.86STSYY1608 pKa = 10.94FGMCGSVVCSRR1619 pKa = 11.84FVDD1622 pKa = 3.63GGGIIGMHH1630 pKa = 6.46CAGGGGVSVGTRR1642 pKa = 11.84LTARR1646 pKa = 11.84MIEE1649 pKa = 4.23SVFDD1653 pKa = 3.36YY1654 pKa = 9.25FYY1656 pKa = 10.86PPVAQGIIEE1665 pKa = 4.1NTEE1668 pKa = 3.62TGPRR1672 pKa = 11.84VHH1674 pKa = 6.75VPRR1677 pKa = 11.84TSKK1680 pKa = 10.76LKK1682 pKa = 9.56RR1683 pKa = 11.84TNATYY1688 pKa = 8.91PATEE1692 pKa = 4.33KK1693 pKa = 10.78YY1694 pKa = 10.62GPAALSRR1701 pKa = 11.84YY1702 pKa = 9.53DD1703 pKa = 3.27PRR1705 pKa = 11.84LNEE1708 pKa = 3.99GVNLDD1713 pKa = 3.47EE1714 pKa = 5.67VIFSKK1719 pKa = 8.98HH1720 pKa = 4.04TQNTLVEE1727 pKa = 4.39KK1728 pKa = 10.9GSTFRR1733 pKa = 11.84SALDD1737 pKa = 3.46MAAEE1741 pKa = 4.29IYY1743 pKa = 10.66GEE1745 pKa = 4.14KK1746 pKa = 10.52FRR1748 pKa = 11.84GNDD1751 pKa = 3.59FSPLSVEE1758 pKa = 4.35DD1759 pKa = 5.12AILGIPGLDD1768 pKa = 2.74RR1769 pKa = 11.84LDD1771 pKa = 4.44PNTASGLPYY1780 pKa = 10.17TKK1782 pKa = 9.69TRR1784 pKa = 11.84RR1785 pKa = 11.84QMIDD1789 pKa = 3.19FNTGQILDD1797 pKa = 4.04DD1798 pKa = 3.77TLKK1801 pKa = 10.81CRR1803 pKa = 11.84LGQWLAGRR1811 pKa = 11.84PPQEE1815 pKa = 3.37VHH1817 pKa = 5.59YY1818 pKa = 9.24QTFLKK1823 pKa = 10.93DD1824 pKa = 3.64EE1825 pKa = 4.03IRR1827 pKa = 11.84PIEE1830 pKa = 4.16KK1831 pKa = 10.27VKK1833 pKa = 10.79AGKK1836 pKa = 7.9TRR1838 pKa = 11.84IIDD1841 pKa = 3.9VPPLDD1846 pKa = 3.69HH1847 pKa = 7.18VIAFRR1852 pKa = 11.84MLFGRR1857 pKa = 11.84FIAHH1861 pKa = 5.05YY1862 pKa = 9.5HH1863 pKa = 5.98LNFGFKK1869 pKa = 9.07TGSAIGCDD1877 pKa = 3.86PDD1879 pKa = 3.85VAWASFGFEE1888 pKa = 3.95LSGFPYY1894 pKa = 10.39LYY1896 pKa = 11.01DD1897 pKa = 3.56FDD1899 pKa = 4.97YY1900 pKa = 11.67SNFDD1904 pKa = 3.55ASHH1907 pKa = 5.52STSIFEE1913 pKa = 4.13ILEE1916 pKa = 3.91QKK1918 pKa = 10.39FFSPEE1923 pKa = 3.61LGFDD1927 pKa = 3.78PRR1929 pKa = 11.84CSLLLKK1935 pKa = 10.33SLAVSTHH1942 pKa = 5.95CYY1944 pKa = 8.41EE1945 pKa = 4.26NKK1947 pKa = 9.91RR1948 pKa = 11.84LQIAGGLPSGTAGTSVLNTVINNIIFHH1975 pKa = 6.35GALYY1979 pKa = 8.48HH1980 pKa = 6.61TYY1982 pKa = 10.79TNFEE1986 pKa = 4.04RR1987 pKa = 11.84DD1988 pKa = 4.55DD1989 pKa = 4.13ISMLAYY1995 pKa = 10.42GDD1997 pKa = 4.92DD1998 pKa = 3.15IVVASKK2004 pKa = 11.22FEE2006 pKa = 4.49LDD2008 pKa = 3.44LVMVKK2013 pKa = 10.9AFMNRR2018 pKa = 11.84IGYY2021 pKa = 9.68KK2022 pKa = 8.63ITPADD2027 pKa = 3.51KK2028 pKa = 10.75SDD2030 pKa = 3.46EE2031 pKa = 4.03FRR2033 pKa = 11.84PKK2035 pKa = 10.81CMDD2038 pKa = 5.12DD2039 pKa = 2.85ICFLKK2044 pKa = 10.63RR2045 pKa = 11.84RR2046 pKa = 11.84FVKK2049 pKa = 10.62VAGVWAPVMEE2059 pKa = 4.42TEE2061 pKa = 4.36NLEE2064 pKa = 5.53AMLSWYY2070 pKa = 10.36KK2071 pKa = 10.66PGTLNEE2077 pKa = 4.2KK2078 pKa = 9.44LQSVSRR2084 pKa = 11.84LAHH2087 pKa = 5.46FSGRR2091 pKa = 11.84DD2092 pKa = 3.57VYY2094 pKa = 11.78DD2095 pKa = 3.5HH2096 pKa = 6.89LFKK2099 pKa = 10.98PFIRR2103 pKa = 11.84DD2104 pKa = 3.53GFDD2107 pKa = 3.03VTPWKK2112 pKa = 10.04QLHH2115 pKa = 6.23LEE2117 pKa = 4.12WLNKK2121 pKa = 10.04LSAA2124 pKa = 4.12

Molecular weight:
235.74 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

2124

2124

2124

2124.0

235.74

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.874 ± 0.0

1.554 ± 0.0

5.932 ± 0.0

4.614 ± 0.0

5.791 ± 0.0

6.685 ± 0.0

2.213 ± 0.0

4.755 ± 0.0

5.603 ± 0.0

8.757 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.872 ± 0.0

4.849 ± 0.0

6.356 ± 0.0

2.919 ± 0.0

4.19 ± 0.0

7.392 ± 0.0

7.486 ± 0.0

6.733 ± 0.0

0.895 ± 0.0

3.531 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski