Amino acid dipepetide frequency for Cosavirus A (isolate Human/Pakistan/0553/-) (HCoSV-A)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.008AlaAla: 8.008 ± 0.0
0.0AlaCys: 0.0 ± 0.0
2.355AlaAsp: 2.355 ± 0.0
2.355AlaGlu: 2.355 ± 0.0
3.297AlaPhe: 3.297 ± 0.0
7.537AlaGly: 7.537 ± 0.0
1.413AlaHis: 1.413 ± 0.0
3.297AlaIle: 3.297 ± 0.0
2.355AlaLys: 2.355 ± 0.0
3.768AlaLeu: 3.768 ± 0.0
1.884AlaMet: 1.884 ± 0.0
3.297AlaAsn: 3.297 ± 0.0
1.884AlaPro: 1.884 ± 0.0
5.652AlaGln: 5.652 ± 0.0
3.768AlaArg: 3.768 ± 0.0
5.181AlaSer: 5.181 ± 0.0
5.652AlaThr: 5.652 ± 0.0
4.239AlaVal: 4.239 ± 0.0
0.471AlaTrp: 0.471 ± 0.0
1.884AlaTyr: 1.884 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.355CysAla: 2.355 ± 0.0
0.471CysCys: 0.471 ± 0.0
0.942CysAsp: 0.942 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.942CysPhe: 0.942 ± 0.0
2.355CysGly: 2.355 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.471CysIle: 0.471 ± 0.0
0.471CysLys: 0.471 ± 0.0
2.355CysLeu: 2.355 ± 0.0
0.471CysMet: 0.471 ± 0.0
0.471CysAsn: 0.471 ± 0.0
0.942CysPro: 0.942 ± 0.0
0.471CysGln: 0.471 ± 0.0
0.471CysArg: 0.471 ± 0.0
1.413CysSer: 1.413 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.942CysTyr: 0.942 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.297AspAla: 3.297 ± 0.0
1.413AspCys: 1.413 ± 0.0
5.181AspAsp: 5.181 ± 0.0
2.826AspGlu: 2.826 ± 0.0
5.181AspPhe: 5.181 ± 0.0
4.239AspGly: 4.239 ± 0.0
1.413AspHis: 1.413 ± 0.0
2.826AspIle: 2.826 ± 0.0
2.826AspLys: 2.826 ± 0.0
5.652AspLeu: 5.652 ± 0.0
1.884AspMet: 1.884 ± 0.0
1.413AspAsn: 1.413 ± 0.0
2.826AspPro: 2.826 ± 0.0
1.413AspGln: 1.413 ± 0.0
2.826AspArg: 2.826 ± 0.0
3.297AspSer: 3.297 ± 0.0
4.239AspThr: 4.239 ± 0.0
2.826AspVal: 2.826 ± 0.0
0.471AspTrp: 0.471 ± 0.0
3.297AspTyr: 3.297 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.413GluAla: 1.413 ± 0.0
0.942GluCys: 0.942 ± 0.0
1.884GluAsp: 1.884 ± 0.0
4.71GluGlu: 4.71 ± 0.0
2.355GluPhe: 2.355 ± 0.0
2.355GluGly: 2.355 ± 0.0
2.355GluHis: 2.355 ± 0.0
2.355GluIle: 2.355 ± 0.0
4.71GluLys: 4.71 ± 0.0
3.768GluLeu: 3.768 ± 0.0
0.471GluMet: 0.471 ± 0.0
2.355GluAsn: 2.355 ± 0.0
1.884GluPro: 1.884 ± 0.0
1.413GluGln: 1.413 ± 0.0
1.884GluArg: 1.884 ± 0.0
2.826GluSer: 2.826 ± 0.0
3.297GluThr: 3.297 ± 0.0
2.826GluVal: 2.826 ± 0.0
1.413GluTrp: 1.413 ± 0.0
0.942GluTyr: 0.942 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.355PheAla: 2.355 ± 0.0
1.413PheCys: 1.413 ± 0.0
5.652PheAsp: 5.652 ± 0.0
3.768PheGlu: 3.768 ± 0.0
2.355PhePhe: 2.355 ± 0.0
2.355PheGly: 2.355 ± 0.0
1.884PheHis: 1.884 ± 0.0
1.884PheIle: 1.884 ± 0.0
2.355PheLys: 2.355 ± 0.0
4.239PheLeu: 4.239 ± 0.0
1.884PheMet: 1.884 ± 0.0
4.239PheAsn: 4.239 ± 0.0
3.768PhePro: 3.768 ± 0.0
1.413PheGln: 1.413 ± 0.0
3.297PheArg: 3.297 ± 0.0
5.652PheSer: 5.652 ± 0.0
1.884PheThr: 1.884 ± 0.0
5.652PheVal: 5.652 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.884PheTyr: 1.884 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.768GlyAla: 3.768 ± 0.0
0.942GlyCys: 0.942 ± 0.0
2.355GlyAsp: 2.355 ± 0.0
3.297GlyGlu: 3.297 ± 0.0
4.71GlyPhe: 4.71 ± 0.0
2.826GlyGly: 2.826 ± 0.0
0.471GlyHis: 0.471 ± 0.0
3.768GlyIle: 3.768 ± 0.0
4.71GlyLys: 4.71 ± 0.0
5.181GlyLeu: 5.181 ± 0.0
3.297GlyMet: 3.297 ± 0.0
3.768GlyAsn: 3.768 ± 0.0
5.652GlyPro: 5.652 ± 0.0
2.826GlyGln: 2.826 ± 0.0
1.884GlyArg: 1.884 ± 0.0
5.652GlySer: 5.652 ± 0.0
5.652GlyThr: 5.652 ± 0.0
3.768GlyVal: 3.768 ± 0.0
0.471GlyTrp: 0.471 ± 0.0
1.884GlyTyr: 1.884 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.884HisAla: 1.884 ± 0.0
1.413HisCys: 1.413 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.471HisGlu: 0.471 ± 0.0
0.942HisPhe: 0.942 ± 0.0
2.355HisGly: 2.355 ± 0.0
0.471HisHis: 0.471 ± 0.0
0.471HisIle: 0.471 ± 0.0
1.413HisLys: 1.413 ± 0.0
1.413HisLeu: 1.413 ± 0.0
0.471HisMet: 0.471 ± 0.0
0.942HisAsn: 0.942 ± 0.0
0.942HisPro: 0.942 ± 0.0
0.471HisGln: 0.471 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.884HisSer: 1.884 ± 0.0
3.297HisThr: 3.297 ± 0.0
0.942HisVal: 0.942 ± 0.0
0.471HisTrp: 0.471 ± 0.0
1.884HisTyr: 1.884 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.71IleAla: 4.71 ± 0.0
0.471IleCys: 0.471 ± 0.0
3.768IleAsp: 3.768 ± 0.0
2.355IleGlu: 2.355 ± 0.0
2.826IlePhe: 2.826 ± 0.0
1.884IleGly: 1.884 ± 0.0
0.0IleHis: 0.0 ± 0.0
1.884IleIle: 1.884 ± 0.0
4.239IleLys: 4.239 ± 0.0
5.181IleLeu: 5.181 ± 0.0
0.471IleMet: 0.471 ± 0.0
2.355IleAsn: 2.355 ± 0.0
1.413IlePro: 1.413 ± 0.0
0.942IleGln: 0.942 ± 0.0
2.355IleArg: 2.355 ± 0.0
3.297IleSer: 3.297 ± 0.0
4.239IleThr: 4.239 ± 0.0
3.297IleVal: 3.297 ± 0.0
0.471IleTrp: 0.471 ± 0.0
1.413IleTyr: 1.413 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.884LysAla: 1.884 ± 0.0
1.413LysCys: 1.413 ± 0.0
5.181LysAsp: 5.181 ± 0.0
3.297LysGlu: 3.297 ± 0.0
1.884LysPhe: 1.884 ± 0.0
3.297LysGly: 3.297 ± 0.0
2.826LysHis: 2.826 ± 0.0
2.826LysIle: 2.826 ± 0.0
4.71LysLys: 4.71 ± 0.0
6.123LysLeu: 6.123 ± 0.0
1.413LysMet: 1.413 ± 0.0
1.884LysAsn: 1.884 ± 0.0
3.297LysPro: 3.297 ± 0.0
1.884LysGln: 1.884 ± 0.0
2.826LysArg: 2.826 ± 0.0
4.239LysSer: 4.239 ± 0.0
2.826LysThr: 2.826 ± 0.0
2.826LysVal: 2.826 ± 0.0
0.471LysTrp: 0.471 ± 0.0
0.942LysTyr: 0.942 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.123LeuAla: 6.123 ± 0.0
0.0LeuCys: 0.0 ± 0.0
6.123LeuAsp: 6.123 ± 0.0
4.239LeuGlu: 4.239 ± 0.0
3.297LeuPhe: 3.297 ± 0.0
4.239LeuGly: 4.239 ± 0.0
2.355LeuHis: 2.355 ± 0.0
3.768LeuIle: 3.768 ± 0.0
7.537LeuLys: 7.537 ± 0.0
8.008LeuLeu: 8.008 ± 0.0
3.768LeuMet: 3.768 ± 0.0
3.768LeuAsn: 3.768 ± 0.0
6.123LeuPro: 6.123 ± 0.0
3.768LeuGln: 3.768 ± 0.0
3.768LeuArg: 3.768 ± 0.0
6.123LeuSer: 6.123 ± 0.0
4.71LeuThr: 4.71 ± 0.0
7.065LeuVal: 7.065 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
2.826LeuTyr: 2.826 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.297MetAla: 3.297 ± 0.0
0.471MetCys: 0.471 ± 0.0
2.826MetAsp: 2.826 ± 0.0
1.413MetGlu: 1.413 ± 0.0
1.413MetPhe: 1.413 ± 0.0
1.413MetGly: 1.413 ± 0.0
0.471MetHis: 0.471 ± 0.0
2.826MetIle: 2.826 ± 0.0
0.471MetLys: 0.471 ± 0.0
3.768MetLeu: 3.768 ± 0.0
1.413MetMet: 1.413 ± 0.0
1.884MetAsn: 1.884 ± 0.0
1.413MetPro: 1.413 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.413MetSer: 1.413 ± 0.0
0.942MetThr: 0.942 ± 0.0
2.355MetVal: 2.355 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.942MetTyr: 0.942 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.826AsnAla: 2.826 ± 0.0
0.0AsnCys: 0.0 ± 0.0
1.884AsnAsp: 1.884 ± 0.0
1.884AsnGlu: 1.884 ± 0.0
4.239AsnPhe: 4.239 ± 0.0
4.239AsnGly: 4.239 ± 0.0
0.0AsnHis: 0.0 ± 0.0
1.884AsnIle: 1.884 ± 0.0
1.884AsnLys: 1.884 ± 0.0
4.71AsnLeu: 4.71 ± 0.0
0.942AsnMet: 0.942 ± 0.0
3.297AsnAsn: 3.297 ± 0.0
4.239AsnPro: 4.239 ± 0.0
0.942AsnGln: 0.942 ± 0.0
1.413AsnArg: 1.413 ± 0.0
4.239AsnSer: 4.239 ± 0.0
6.594AsnThr: 6.594 ± 0.0
2.826AsnVal: 2.826 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
0.471AsnTyr: 0.471 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.297ProAla: 3.297 ± 0.0
0.942ProCys: 0.942 ± 0.0
3.768ProAsp: 3.768 ± 0.0
3.768ProGlu: 3.768 ± 0.0
5.181ProPhe: 5.181 ± 0.0
5.652ProGly: 5.652 ± 0.0
1.884ProHis: 1.884 ± 0.0
3.297ProIle: 3.297 ± 0.0
2.355ProLys: 2.355 ± 0.0
4.71ProLeu: 4.71 ± 0.0
0.942ProMet: 0.942 ± 0.0
0.471ProAsn: 0.471 ± 0.0
5.181ProPro: 5.181 ± 0.0
1.413ProGln: 1.413 ± 0.0
4.239ProArg: 4.239 ± 0.0
2.826ProSer: 2.826 ± 0.0
5.652ProThr: 5.652 ± 0.0
4.239ProVal: 4.239 ± 0.0
0.942ProTrp: 0.942 ± 0.0
2.826ProTyr: 2.826 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.884GlnAla: 1.884 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.413GlnGlu: 1.413 ± 0.0
1.884GlnPhe: 1.884 ± 0.0
3.297GlnGly: 3.297 ± 0.0
0.471GlnHis: 0.471 ± 0.0
2.355GlnIle: 2.355 ± 0.0
1.413GlnLys: 1.413 ± 0.0
2.826GlnLeu: 2.826 ± 0.0
0.942GlnMet: 0.942 ± 0.0
1.413GlnAsn: 1.413 ± 0.0
0.471GlnPro: 0.471 ± 0.0
1.413GlnGln: 1.413 ± 0.0
0.942GlnArg: 0.942 ± 0.0
2.826GlnSer: 2.826 ± 0.0
1.884GlnThr: 1.884 ± 0.0
0.942GlnVal: 0.942 ± 0.0
1.884GlnTrp: 1.884 ± 0.0
0.942GlnTyr: 0.942 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.826ArgAla: 2.826 ± 0.0
1.413ArgCys: 1.413 ± 0.0
3.768ArgAsp: 3.768 ± 0.0
0.471ArgGlu: 0.471 ± 0.0
2.826ArgPhe: 2.826 ± 0.0
2.826ArgGly: 2.826 ± 0.0
0.471ArgHis: 0.471 ± 0.0
1.884ArgIle: 1.884 ± 0.0
1.413ArgLys: 1.413 ± 0.0
6.123ArgLeu: 6.123 ± 0.0
0.942ArgMet: 0.942 ± 0.0
1.413ArgAsn: 1.413 ± 0.0
4.239ArgPro: 4.239 ± 0.0
0.471ArgGln: 0.471 ± 0.0
1.413ArgArg: 1.413 ± 0.0
1.413ArgSer: 1.413 ± 0.0
2.826ArgThr: 2.826 ± 0.0
2.355ArgVal: 2.355 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
2.826ArgTyr: 2.826 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.71SerAla: 4.71 ± 0.0
1.413SerCys: 1.413 ± 0.0
5.181SerAsp: 5.181 ± 0.0
1.413SerGlu: 1.413 ± 0.0
5.181SerPhe: 5.181 ± 0.0
5.181SerGly: 5.181 ± 0.0
0.942SerHis: 0.942 ± 0.0
2.355SerIle: 2.355 ± 0.0
3.768SerLys: 3.768 ± 0.0
7.065SerLeu: 7.065 ± 0.0
0.471SerMet: 0.471 ± 0.0
5.181SerAsn: 5.181 ± 0.0
6.123SerPro: 6.123 ± 0.0
0.942SerGln: 0.942 ± 0.0
3.297SerArg: 3.297 ± 0.0
3.297SerSer: 3.297 ± 0.0
5.181SerThr: 5.181 ± 0.0
8.95SerVal: 8.95 ± 0.0
0.471SerTrp: 0.471 ± 0.0
2.826SerTyr: 2.826 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.71ThrAla: 4.71 ± 0.0
0.471ThrCys: 0.471 ± 0.0
2.826ThrAsp: 2.826 ± 0.0
5.181ThrGlu: 5.181 ± 0.0
3.297ThrPhe: 3.297 ± 0.0
3.297ThrGly: 3.297 ± 0.0
0.942ThrHis: 0.942 ± 0.0
2.826ThrIle: 2.826 ± 0.0
3.297ThrLys: 3.297 ± 0.0
6.594ThrLeu: 6.594 ± 0.0
1.884ThrMet: 1.884 ± 0.0
3.768ThrAsn: 3.768 ± 0.0
6.123ThrPro: 6.123 ± 0.0
1.884ThrGln: 1.884 ± 0.0
3.297ThrArg: 3.297 ± 0.0
9.421ThrSer: 9.421 ± 0.0
5.652ThrThr: 5.652 ± 0.0
6.123ThrVal: 6.123 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
3.297ThrTyr: 3.297 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.123ValAla: 6.123 ± 0.0
2.355ValCys: 2.355 ± 0.0
2.826ValAsp: 2.826 ± 0.0
2.355ValGlu: 2.355 ± 0.0
1.884ValPhe: 1.884 ± 0.0
4.71ValGly: 4.71 ± 0.0
2.355ValHis: 2.355 ± 0.0
2.826ValIle: 2.826 ± 0.0
3.297ValLys: 3.297 ± 0.0
3.297ValLeu: 3.297 ± 0.0
3.768ValMet: 3.768 ± 0.0
3.297ValAsn: 3.297 ± 0.0
4.71ValPro: 4.71 ± 0.0
0.942ValGln: 0.942 ± 0.0
1.884ValArg: 1.884 ± 0.0
6.594ValSer: 6.594 ± 0.0
5.652ValThr: 5.652 ± 0.0
5.652ValVal: 5.652 ± 0.0
1.413ValTrp: 1.413 ± 0.0
1.413ValTyr: 1.413 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.942TrpAla: 0.942 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.471TrpAsp: 0.471 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.942TrpIle: 0.942 ± 0.0
0.942TrpLys: 0.942 ± 0.0
1.884TrpLeu: 1.884 ± 0.0
0.471TrpMet: 0.471 ± 0.0
0.942TrpAsn: 0.942 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.471TrpThr: 0.471 ± 0.0
0.471TrpVal: 0.471 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.413TrpTyr: 1.413 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.355TyrAla: 2.355 ± 0.0
0.0TyrCys: 0.0 ± 0.0
2.355TyrAsp: 2.355 ± 0.0
0.942TyrGlu: 0.942 ± 0.0
4.239TyrPhe: 4.239 ± 0.0
2.826TyrGly: 2.826 ± 0.0
1.413TyrHis: 1.413 ± 0.0
2.826TyrIle: 2.826 ± 0.0
1.884TyrLys: 1.884 ± 0.0
0.942TyrLeu: 0.942 ± 0.0
0.471TyrMet: 0.471 ± 0.0
2.355TyrAsn: 2.355 ± 0.0
2.355TyrPro: 2.355 ± 0.0
0.942TyrGln: 0.942 ± 0.0
2.355TyrArg: 2.355 ± 0.0
2.355TyrSer: 2.355 ± 0.0
4.239TyrThr: 4.239 ± 0.0
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.471TyrTyr: 0.471 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2124 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski