human papillomavirus 153

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 13

Average proteome isoelectric point is 5.98

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|G8GMN0|G8GMN0_9PAPI Major capsid protein L1 OS=human papillomavirus 153 OX=1110710 GN=L1 PE=3 SV=1
MM1 pKa = 7.38SNNRR5 pKa = 11.84KK6 pKa = 9.02RR7 pKa = 11.84RR8 pKa = 11.84AAPIDD13 pKa = 4.13LYY15 pKa = 11.09KK16 pKa = 10.2SCQMGGDD23 pKa = 4.47CFPDD27 pKa = 3.35VQNKK31 pKa = 9.49IEE33 pKa = 4.19GTTLADD39 pKa = 3.55RR40 pKa = 11.84LLQIFSSVLYY50 pKa = 10.39FGGLGIGSGKK60 pKa = 8.44GTGGSTGYY68 pKa = 10.81KK69 pKa = 9.67PLTPGATQRR78 pKa = 11.84PSQFPQTFRR87 pKa = 11.84PTIPIDD93 pKa = 3.58PLGGADD99 pKa = 5.25VIPLDD104 pKa = 4.98IIDD107 pKa = 4.54ASTPSVVPLIDD118 pKa = 3.68GTPEE122 pKa = 3.63TTIISSGTGPTVEE135 pKa = 5.19IGDD138 pKa = 4.41LDD140 pKa = 3.68VTTTVDD146 pKa = 3.18ISATSVARR154 pKa = 11.84GDD156 pKa = 3.55HH157 pKa = 6.39PAIIDD162 pKa = 3.41ISEE165 pKa = 4.34EE166 pKa = 4.12GSSVIDD172 pKa = 3.88VQNGPPPPKK181 pKa = 10.08KK182 pKa = 10.4LQLDD186 pKa = 3.88TLLNPPEE193 pKa = 4.63TIDD196 pKa = 4.85LVTPPTTTYY205 pKa = 10.46RR206 pKa = 11.84DD207 pKa = 3.32SNINVFVDD215 pKa = 3.67THH217 pKa = 7.5ISGEE221 pKa = 4.34VIGAEE226 pKa = 4.29SIPLDD231 pKa = 3.68EE232 pKa = 5.69LSTIEE237 pKa = 3.84QFEE240 pKa = 4.29IEE242 pKa = 4.58EE243 pKa = 4.34PRR245 pKa = 11.84QTSTPEE251 pKa = 3.38ARR253 pKa = 11.84LNKK256 pKa = 10.07AIYY259 pKa = 8.93KK260 pKa = 10.57AKK262 pKa = 9.07TLYY265 pKa = 10.58NRR267 pKa = 11.84FVKK270 pKa = 10.0QVPTQDD276 pKa = 3.46LHH278 pKa = 6.68TLLQPSRR285 pKa = 11.84QVTFEE290 pKa = 3.71FDD292 pKa = 3.13NPAFSDD298 pKa = 3.65DD299 pKa = 3.63VSFEE303 pKa = 4.38FINDD307 pKa = 3.69LQEE310 pKa = 3.78VTAAPNPDD318 pKa = 3.37FQDD321 pKa = 2.95IQTLSRR327 pKa = 11.84PIISEE332 pKa = 4.17TEE334 pKa = 4.08SGSVRR339 pKa = 11.84YY340 pKa = 9.8SRR342 pKa = 11.84LGQRR346 pKa = 11.84ASMQTRR352 pKa = 11.84SGLVIGEE359 pKa = 4.33KK360 pKa = 9.73VHH362 pKa = 7.24FYY364 pKa = 11.22YY365 pKa = 10.66DD366 pKa = 3.72LSTIEE371 pKa = 4.29PADD374 pKa = 4.15SIEE377 pKa = 4.65LSTFVNTSADD387 pKa = 3.47AIVQNEE393 pKa = 4.14QIEE396 pKa = 4.71SLFIDD401 pKa = 4.09EE402 pKa = 5.55ASALLPDD409 pKa = 4.57EE410 pKa = 4.93EE411 pKa = 5.17LLDD414 pKa = 3.93SAAEE418 pKa = 4.16SFRR421 pKa = 11.84NSHH424 pKa = 6.33LVFSFTNEE432 pKa = 3.45EE433 pKa = 4.36AEE435 pKa = 4.55TVTLPILPSNFGLQPYY451 pKa = 10.19IPDD454 pKa = 3.33QFKK457 pKa = 10.87KK458 pKa = 10.57IFVSYY463 pKa = 9.26PISGSDD469 pKa = 3.41VAPYY473 pKa = 10.27LPSIPLSPLYY483 pKa = 8.52PTEE486 pKa = 3.82VTVYY490 pKa = 10.5GDD492 pKa = 3.77SFVIDD497 pKa = 3.66PFFLKK502 pKa = 10.34RR503 pKa = 11.84KK504 pKa = 8.0RR505 pKa = 11.84KK506 pKa = 9.91RR507 pKa = 11.84YY508 pKa = 7.13TLYY511 pKa = 11.02

Molecular weight: 55.98 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|G8GMM8|G8GMM8_9PAPI E4 protein OS=human papillomavirus 153 OX=1110710 GN=E4 PE=4 SV=1
MM1 pKa = 6.96NQAEE5 pKa = 4.22LTARR9 pKa = 11.84FDD11 pKa = 3.78ALQEE15 pKa = 3.95EE16 pKa = 5.01LLNLIEE22 pKa = 4.85AAGDD26 pKa = 3.68DD27 pKa = 4.43LEE29 pKa = 4.39TQIRR33 pKa = 11.84HH34 pKa = 5.23WDD36 pKa = 3.56LNRR39 pKa = 11.84KK40 pKa = 9.19LNVYY44 pKa = 9.01MYY46 pKa = 9.43YY47 pKa = 10.64GRR49 pKa = 11.84KK50 pKa = 9.08EE51 pKa = 4.33GIRR54 pKa = 11.84HH55 pKa = 6.51FGLQQLPTLQVSEE68 pKa = 4.71YY69 pKa = 9.19NAKK72 pKa = 10.15LAISISILLKK82 pKa = 10.68SLAKK86 pKa = 10.45SRR88 pKa = 11.84FAYY91 pKa = 9.03EE92 pKa = 3.39KK93 pKa = 8.8WTFADD98 pKa = 4.21TSAEE102 pKa = 4.4LILTPPKK109 pKa = 10.73NCLKK113 pKa = 10.53KK114 pKa = 10.19SAYY117 pKa = 7.69TVQVIYY123 pKa = 10.91DD124 pKa = 4.33DD125 pKa = 5.38DD126 pKa = 4.51PEE128 pKa = 4.72NMSVHH133 pKa = 5.9TNWDD137 pKa = 3.43HH138 pKa = 7.86IYY140 pKa = 10.32YY141 pKa = 9.94QDD143 pKa = 6.09LEE145 pKa = 4.57EE146 pKa = 4.28QWHH149 pKa = 5.68KK150 pKa = 11.37VPGQVDD156 pKa = 4.13HH157 pKa = 7.31NGMFYY162 pKa = 11.12DD163 pKa = 5.21DD164 pKa = 3.89ILGEE168 pKa = 3.83RR169 pKa = 11.84VYY171 pKa = 10.67FHH173 pKa = 6.73VFAPDD178 pKa = 3.24ADD180 pKa = 4.37TYY182 pKa = 11.53SKK184 pKa = 10.02TGTWTVKK191 pKa = 10.59YY192 pKa = 10.03KK193 pKa = 9.87STTISSVVTSSSKK206 pKa = 9.92QSSRR210 pKa = 11.84GYY212 pKa = 9.06SARR215 pKa = 11.84DD216 pKa = 3.13STTSSRR222 pKa = 11.84CSSPEE227 pKa = 3.59EE228 pKa = 4.42GPSTRR233 pKa = 11.84RR234 pKa = 11.84SEE236 pKa = 4.16TSRR239 pKa = 11.84QEE241 pKa = 3.94SSGCSPTSSSLGNRR255 pKa = 11.84RR256 pKa = 11.84RR257 pKa = 11.84RR258 pKa = 11.84NQQGEE263 pKa = 4.55SEE265 pKa = 4.36SQRR268 pKa = 11.84DD269 pKa = 3.55SGGTSGKK276 pKa = 9.64RR277 pKa = 11.84KK278 pKa = 9.79RR279 pKa = 11.84PISLGVSAEE288 pKa = 4.26AVGSRR293 pKa = 11.84HH294 pKa = 6.33RR295 pKa = 11.84SLPRR299 pKa = 11.84QGLGRR304 pKa = 11.84LEE306 pKa = 4.25RR307 pKa = 11.84LTEE310 pKa = 3.92EE311 pKa = 4.84ARR313 pKa = 11.84DD314 pKa = 3.67PPIIIIKK321 pKa = 10.47GPANNLKK328 pKa = 10.1CWRR331 pKa = 11.84FRR333 pKa = 11.84CNNRR337 pKa = 11.84YY338 pKa = 8.71GHH340 pKa = 7.16LFSSISTVFRR350 pKa = 11.84WVEE353 pKa = 3.61DD354 pKa = 3.84CNNKK358 pKa = 9.74NEE360 pKa = 4.21AFFGSRR366 pKa = 11.84MLIAFKK372 pKa = 11.01DD373 pKa = 3.3NTQRR377 pKa = 11.84QKK379 pKa = 11.05FLSTVHH385 pKa = 6.79LPRR388 pKa = 11.84NTTYY392 pKa = 11.72ALGFLDD398 pKa = 4.7SLL400 pKa = 4.36

Molecular weight: 45.56 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2410

96

605

344.3

38.94

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.602 ± 0.531

2.365 ± 0.978

6.763 ± 0.445

6.1 ± 0.614

4.772 ± 0.429

5.187 ± 0.532

2.365 ± 0.556

5.726 ± 0.678

5.145 ± 0.63

9.585 ± 0.679

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.245 ± 0.25

5.145 ± 0.686

6.017 ± 1.113

4.564 ± 0.277

5.56 ± 0.713

7.718 ± 1.062

6.349 ± 0.804

5.394 ± 0.365

1.203 ± 0.356

3.195 ± 0.249
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski