Amino acid dipepetide frequency for Hubei sobemo-like virus 26

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.876AlaAla: 6.876 ± 2.349
0.982AlaCys: 0.982 ± 0.549
1.965AlaAsp: 1.965 ± 0.394
3.929AlaGlu: 3.929 ± 0.703
4.912AlaPhe: 4.912 ± 1.252
5.894AlaGly: 5.894 ± 0.309
2.947AlaHis: 2.947 ± 0.155
0.982AlaIle: 0.982 ± 0.549
6.876AlaLys: 6.876 ± 0.634
4.912AlaLeu: 4.912 ± 1.252
0.982AlaMet: 0.982 ± 0.549
5.894AlaAsn: 5.894 ± 0.309
2.947AlaPro: 2.947 ± 0.155
1.965AlaGln: 1.965 ± 1.097
7.859AlaArg: 7.859 ± 0.085
5.894AlaSer: 5.894 ± 1.182
3.929AlaThr: 3.929 ± 0.788
8.841AlaVal: 8.841 ± 3.446
0.982AlaTrp: 0.982 ± 0.943
2.947AlaTyr: 2.947 ± 0.155
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.965CysAsp: 1.965 ± 0.394
0.982CysGlu: 0.982 ± 0.549
0.982CysPhe: 0.982 ± 0.549
0.0CysGly: 0.0 ± 0.0
0.982CysHis: 0.982 ± 0.549
1.965CysIle: 1.965 ± 1.885
0.0CysLys: 0.0 ± 0.0
1.965CysLeu: 1.965 ± 0.394
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.965CysGln: 1.965 ± 0.394
0.982CysArg: 0.982 ± 0.549
0.982CysSer: 0.982 ± 0.549
0.982CysThr: 0.982 ± 0.549
2.947CysVal: 2.947 ± 1.337
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.929AspAla: 3.929 ± 0.788
0.982AspCys: 0.982 ± 0.549
5.894AspAsp: 5.894 ± 1.182
3.929AspGlu: 3.929 ± 2.279
2.947AspPhe: 2.947 ± 0.155
2.947AspGly: 2.947 ± 0.155
0.982AspHis: 0.982 ± 0.943
0.0AspIle: 0.0 ± 0.0
0.982AspLys: 0.982 ± 0.549
1.965AspLeu: 1.965 ± 1.097
0.982AspMet: 0.982 ± 0.943
1.965AspAsn: 1.965 ± 1.885
0.982AspPro: 0.982 ± 0.943
2.947AspGln: 2.947 ± 2.828
4.912AspArg: 4.912 ± 1.731
0.982AspSer: 0.982 ± 0.549
1.965AspThr: 1.965 ± 1.097
2.947AspVal: 2.947 ± 0.155
4.912AspTrp: 4.912 ± 0.239
0.982AspTyr: 0.982 ± 0.549
0.0AspXaa: 0.0 ± 0.0
Glu
6.876GluAla: 6.876 ± 0.634
0.982GluCys: 0.982 ± 0.549
1.965GluAsp: 1.965 ± 1.097
4.912GluGlu: 4.912 ± 2.743
5.894GluPhe: 5.894 ± 1.182
1.965GluGly: 1.965 ± 1.097
0.0GluHis: 0.0 ± 0.0
1.965GluIle: 1.965 ± 1.097
4.912GluLys: 4.912 ± 1.252
5.894GluLeu: 5.894 ± 2.673
1.965GluMet: 1.965 ± 0.394
0.0GluAsn: 0.0 ± 0.0
2.947GluPro: 2.947 ± 1.646
2.947GluGln: 2.947 ± 0.155
5.894GluArg: 5.894 ± 0.309
7.859GluSer: 7.859 ± 2.897
0.982GluThr: 0.982 ± 0.549
3.929GluVal: 3.929 ± 0.788
0.982GluTrp: 0.982 ± 0.549
0.982GluTyr: 0.982 ± 0.549
0.0GluXaa: 0.0 ± 0.0
Phe
2.947PheAla: 2.947 ± 0.155
0.982PheCys: 0.982 ± 0.943
4.912PheAsp: 4.912 ± 0.239
0.982PheGlu: 0.982 ± 0.943
0.982PhePhe: 0.982 ± 0.549
3.929PheGly: 3.929 ± 0.788
0.0PheHis: 0.0 ± 0.0
2.947PheIle: 2.947 ± 2.828
0.0PheLys: 0.0 ± 0.0
4.912PheLeu: 4.912 ± 0.239
1.965PheMet: 1.965 ± 0.929
1.965PheAsn: 1.965 ± 1.885
1.965PhePro: 1.965 ± 1.097
2.947PheGln: 2.947 ± 1.646
2.947PheArg: 2.947 ± 0.155
5.894PheSer: 5.894 ± 1.8
1.965PheThr: 1.965 ± 0.394
1.965PheVal: 1.965 ± 0.394
0.982PheTrp: 0.982 ± 0.549
0.982PheTyr: 0.982 ± 0.549
0.0PheXaa: 0.0 ± 0.0
Gly
5.894GlyAla: 5.894 ± 3.291
2.947GlyCys: 2.947 ± 1.337
2.947GlyAsp: 2.947 ± 1.337
6.876GlyGlu: 6.876 ± 3.84
3.929GlyPhe: 3.929 ± 0.788
2.947GlyGly: 2.947 ± 1.337
1.965GlyHis: 1.965 ± 1.097
2.947GlyIle: 2.947 ± 0.155
6.876GlyLys: 6.876 ± 0.858
8.841GlyLeu: 8.841 ± 0.464
4.912GlyMet: 4.912 ± 1.252
0.0GlyAsn: 0.0 ± 0.0
0.982GlyPro: 0.982 ± 0.549
3.929GlyGln: 3.929 ± 2.194
0.982GlyArg: 0.982 ± 0.549
3.929GlySer: 3.929 ± 0.703
1.965GlyThr: 1.965 ± 1.885
1.965GlyVal: 1.965 ± 0.394
1.965GlyTrp: 1.965 ± 1.885
2.947GlyTyr: 2.947 ± 1.337
0.0GlyXaa: 0.0 ± 0.0
His
1.965HisAla: 1.965 ± 1.885
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.982HisPhe: 0.982 ± 0.943
0.982HisGly: 0.982 ± 0.549
0.982HisHis: 0.982 ± 0.549
0.0HisIle: 0.0 ± 0.0
1.965HisLys: 1.965 ± 0.394
1.965HisLeu: 1.965 ± 1.097
2.947HisMet: 2.947 ± 1.337
0.0HisAsn: 0.0 ± 0.0
0.982HisPro: 0.982 ± 0.549
2.947HisGln: 2.947 ± 1.646
0.982HisArg: 0.982 ± 0.943
0.0HisSer: 0.0 ± 0.0
1.965HisThr: 1.965 ± 0.394
0.982HisVal: 0.982 ± 0.549
0.0HisTrp: 0.0 ± 0.0
1.965HisTyr: 1.965 ± 1.097
0.0HisXaa: 0.0 ± 0.0
Ile
1.965IleAla: 1.965 ± 1.885
0.0IleCys: 0.0 ± 0.0
1.965IleAsp: 1.965 ± 1.097
2.947IleGlu: 2.947 ± 0.155
0.982IlePhe: 0.982 ± 0.943
0.982IleGly: 0.982 ± 0.549
0.982IleHis: 0.982 ± 0.549
1.965IleIle: 1.965 ± 0.394
2.947IleLys: 2.947 ± 0.155
6.876IleLeu: 6.876 ± 0.634
0.982IleMet: 0.982 ± 0.943
0.982IleAsn: 0.982 ± 0.549
2.947IlePro: 2.947 ± 2.828
0.0IleGln: 0.0 ± 0.0
2.947IleArg: 2.947 ± 0.155
3.929IleSer: 3.929 ± 2.279
0.0IleThr: 0.0 ± 0.0
5.894IleVal: 5.894 ± 0.309
0.982IleTrp: 0.982 ± 0.943
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.929LysAla: 3.929 ± 0.788
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
4.912LysGlu: 4.912 ± 1.252
2.947LysPhe: 2.947 ± 1.646
3.929LysGly: 3.929 ± 0.788
0.982LysHis: 0.982 ± 0.943
0.0LysIle: 0.0 ± 0.0
4.912LysLys: 4.912 ± 1.252
4.912LysLeu: 4.912 ± 1.252
1.965LysMet: 1.965 ± 1.097
0.982LysAsn: 0.982 ± 0.943
3.929LysPro: 3.929 ± 0.788
1.965LysGln: 1.965 ± 0.394
0.982LysArg: 0.982 ± 0.549
7.859LysSer: 7.859 ± 0.085
0.982LysThr: 0.982 ± 0.943
3.929LysVal: 3.929 ± 0.703
0.0LysTrp: 0.0 ± 0.0
0.982LysTyr: 0.982 ± 0.549
0.0LysXaa: 0.0 ± 0.0
Leu
10.806LeuAla: 10.806 ± 3.052
0.982LeuCys: 0.982 ± 0.943
5.894LeuAsp: 5.894 ± 0.309
4.912LeuGlu: 4.912 ± 1.731
6.876LeuPhe: 6.876 ± 3.616
4.912LeuGly: 4.912 ± 1.252
1.965LeuHis: 1.965 ± 1.885
5.894LeuIle: 5.894 ± 0.309
3.929LeuLys: 3.929 ± 2.279
8.841LeuLeu: 8.841 ± 0.464
0.982LeuMet: 0.982 ± 0.549
2.947LeuAsn: 2.947 ± 0.155
3.929LeuPro: 3.929 ± 0.703
1.965LeuGln: 1.965 ± 1.885
8.841LeuArg: 8.841 ± 1.955
6.876LeuSer: 6.876 ± 2.349
2.947LeuThr: 2.947 ± 0.155
5.894LeuVal: 5.894 ± 1.8
0.0LeuTrp: 0.0 ± 0.0
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.929MetAla: 3.929 ± 2.279
0.0MetCys: 0.0 ± 0.0
1.965MetAsp: 1.965 ± 0.394
1.965MetGlu: 1.965 ± 0.394
1.965MetPhe: 1.965 ± 0.394
1.965MetGly: 1.965 ± 1.885
0.0MetHis: 0.0 ± 0.0
0.982MetIle: 0.982 ± 0.549
0.982MetLys: 0.982 ± 0.943
2.947MetLeu: 2.947 ± 1.337
0.982MetMet: 0.982 ± 0.549
1.965MetAsn: 1.965 ± 0.394
0.982MetPro: 0.982 ± 0.943
0.982MetGln: 0.982 ± 0.943
3.929MetArg: 3.929 ± 0.703
2.947MetSer: 2.947 ± 1.646
0.0MetThr: 0.0 ± 0.0
2.947MetVal: 2.947 ± 1.646
0.982MetTrp: 0.982 ± 0.549
1.965MetTyr: 1.965 ± 1.097
0.0MetXaa: 0.0 ± 0.0
Asn
1.965AsnAla: 1.965 ± 1.097
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.965AsnGlu: 1.965 ± 0.394
0.0AsnPhe: 0.0 ± 0.0
1.965AsnGly: 1.965 ± 1.885
0.982AsnHis: 0.982 ± 0.549
0.982AsnIle: 0.982 ± 0.943
0.982AsnLys: 0.982 ± 0.943
1.965AsnLeu: 1.965 ± 1.885
0.982AsnMet: 0.982 ± 0.441
1.965AsnAsn: 1.965 ± 0.394
0.0AsnPro: 0.0 ± 0.0
0.982AsnGln: 0.982 ± 0.549
0.982AsnArg: 0.982 ± 0.549
4.912AsnSer: 4.912 ± 0.239
3.929AsnThr: 3.929 ± 0.703
3.929AsnVal: 3.929 ± 0.703
2.947AsnTrp: 2.947 ± 1.337
1.965AsnTyr: 1.965 ± 0.394
0.0AsnXaa: 0.0 ± 0.0
Pro
0.982ProAla: 0.982 ± 0.549
1.965ProCys: 1.965 ± 1.097
1.965ProAsp: 1.965 ± 1.097
3.929ProGlu: 3.929 ± 0.788
2.947ProPhe: 2.947 ± 1.337
8.841ProGly: 8.841 ± 0.464
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
2.947ProLys: 2.947 ± 1.646
0.982ProLeu: 0.982 ± 0.549
0.982ProMet: 0.982 ± 0.943
0.982ProAsn: 0.982 ± 0.943
0.982ProPro: 0.982 ± 0.549
0.0ProGln: 0.0 ± 0.0
2.947ProArg: 2.947 ± 0.155
5.894ProSer: 5.894 ± 1.182
0.982ProThr: 0.982 ± 0.549
5.894ProVal: 5.894 ± 1.182
1.965ProTrp: 1.965 ± 1.885
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.929GlnAla: 3.929 ± 0.788
0.982GlnCys: 0.982 ± 0.549
1.965GlnAsp: 1.965 ± 0.394
1.965GlnGlu: 1.965 ± 1.097
2.947GlnPhe: 2.947 ± 1.337
4.912GlnGly: 4.912 ± 1.252
0.0GlnHis: 0.0 ± 0.0
1.965GlnIle: 1.965 ± 1.885
2.947GlnLys: 2.947 ± 1.337
2.947GlnLeu: 2.947 ± 0.155
0.0GlnMet: 0.0 ± 0.0
4.912GlnAsn: 4.912 ± 1.252
1.965GlnPro: 1.965 ± 0.394
0.0GlnGln: 0.0 ± 0.0
0.982GlnArg: 0.982 ± 0.943
2.947GlnSer: 2.947 ± 1.646
0.982GlnThr: 0.982 ± 0.549
3.929GlnVal: 3.929 ± 0.703
0.982GlnTrp: 0.982 ± 0.943
0.982GlnTyr: 0.982 ± 0.549
0.0GlnXaa: 0.0 ± 0.0
Arg
6.876ArgAla: 6.876 ± 2.349
0.982ArgCys: 0.982 ± 0.549
1.965ArgAsp: 1.965 ± 1.885
1.965ArgGlu: 1.965 ± 0.394
1.965ArgPhe: 1.965 ± 0.394
3.929ArgGly: 3.929 ± 0.703
1.965ArgHis: 1.965 ± 1.097
4.912ArgIle: 4.912 ± 0.239
2.947ArgLys: 2.947 ± 1.646
7.859ArgLeu: 7.859 ± 1.576
0.982ArgMet: 0.982 ± 0.943
1.965ArgAsn: 1.965 ± 0.394
3.929ArgPro: 3.929 ± 0.703
2.947ArgGln: 2.947 ± 0.155
1.965ArgArg: 1.965 ± 0.394
3.929ArgSer: 3.929 ± 0.788
2.947ArgThr: 2.947 ± 0.155
6.876ArgVal: 6.876 ± 0.858
2.947ArgTrp: 2.947 ± 0.155
3.929ArgTyr: 3.929 ± 0.788
0.0ArgXaa: 0.0 ± 0.0
Ser
8.841SerAla: 8.841 ± 3.446
1.965SerCys: 1.965 ± 0.394
2.947SerAsp: 2.947 ± 1.337
6.876SerGlu: 6.876 ± 0.858
1.965SerPhe: 1.965 ± 1.097
7.859SerGly: 7.859 ± 0.085
2.947SerHis: 2.947 ± 0.155
5.894SerIle: 5.894 ± 1.182
2.947SerLys: 2.947 ± 0.155
2.947SerLeu: 2.947 ± 1.646
3.929SerMet: 3.929 ± 0.788
0.982SerAsn: 0.982 ± 0.549
3.929SerPro: 3.929 ± 0.788
6.876SerGln: 6.876 ± 2.349
1.965SerArg: 1.965 ± 1.097
4.912SerSer: 4.912 ± 0.239
2.947SerThr: 2.947 ± 0.155
7.859SerVal: 7.859 ± 0.085
0.982SerTrp: 0.982 ± 0.549
2.947SerTyr: 2.947 ± 1.337
0.0SerXaa: 0.0 ± 0.0
Thr
2.947ThrAla: 2.947 ± 1.337
1.965ThrCys: 1.965 ± 0.394
3.929ThrAsp: 3.929 ± 0.788
1.965ThrGlu: 1.965 ± 1.097
0.982ThrPhe: 0.982 ± 0.549
4.912ThrGly: 4.912 ± 2.743
0.0ThrHis: 0.0 ± 0.0
0.982ThrIle: 0.982 ± 0.943
0.982ThrLys: 0.982 ± 0.549
5.894ThrLeu: 5.894 ± 1.8
0.982ThrMet: 0.982 ± 0.549
0.982ThrAsn: 0.982 ± 0.549
1.965ThrPro: 1.965 ± 1.885
0.982ThrGln: 0.982 ± 0.943
0.982ThrArg: 0.982 ± 0.943
3.929ThrSer: 3.929 ± 2.279
0.982ThrThr: 0.982 ± 0.549
0.982ThrVal: 0.982 ± 0.943
0.0ThrTrp: 0.0 ± 0.0
0.982ThrTyr: 0.982 ± 0.549
0.0ThrXaa: 0.0 ± 0.0
Val
5.894ValAla: 5.894 ± 1.8
0.982ValCys: 0.982 ± 0.943
3.929ValAsp: 3.929 ± 3.77
3.929ValGlu: 3.929 ± 2.194
2.947ValPhe: 2.947 ± 1.646
4.912ValGly: 4.912 ± 1.252
2.947ValHis: 2.947 ± 0.155
2.947ValIle: 2.947 ± 0.155
1.965ValLys: 1.965 ± 1.097
7.859ValLeu: 7.859 ± 1.576
1.965ValMet: 1.965 ± 0.394
3.929ValAsn: 3.929 ± 0.788
6.876ValPro: 6.876 ± 2.349
4.912ValGln: 4.912 ± 1.731
7.859ValArg: 7.859 ± 1.406
3.929ValSer: 3.929 ± 2.194
3.929ValThr: 3.929 ± 0.788
4.912ValVal: 4.912 ± 1.731
0.982ValTrp: 0.982 ± 0.943
1.965ValTyr: 1.965 ± 1.097
0.0ValXaa: 0.0 ± 0.0
Trp
0.982TrpAla: 0.982 ± 0.549
0.0TrpCys: 0.0 ± 0.0
0.982TrpAsp: 0.982 ± 0.943
0.982TrpGlu: 0.982 ± 0.549
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.965TrpIle: 1.965 ± 1.097
0.0TrpLys: 0.0 ± 0.0
2.947TrpLeu: 2.947 ± 0.155
1.965TrpMet: 1.965 ± 1.885
0.982TrpAsn: 0.982 ± 0.549
0.982TrpPro: 0.982 ± 0.943
0.982TrpGln: 0.982 ± 0.943
3.929TrpArg: 3.929 ± 2.279
2.947TrpSer: 2.947 ± 1.337
2.947TrpThr: 2.947 ± 1.337
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.982TyrAla: 0.982 ± 0.549
0.0TyrCys: 0.0 ± 0.0
0.982TyrAsp: 0.982 ± 0.549
3.929TyrGlu: 3.929 ± 0.703
0.0TyrPhe: 0.0 ± 0.0
1.965TyrGly: 1.965 ± 1.097
0.982TyrHis: 0.982 ± 0.943
0.982TyrIle: 0.982 ± 0.943
0.0TyrLys: 0.0 ± 0.0
1.965TyrLeu: 1.965 ± 1.097
2.947TyrMet: 2.947 ± 1.646
0.0TyrAsn: 0.0 ± 0.0
1.965TyrPro: 1.965 ± 0.394
0.0TyrGln: 0.0 ± 0.0
4.912TyrArg: 4.912 ± 0.239
1.965TyrSer: 1.965 ± 1.097
0.0TyrThr: 0.0 ± 0.0
2.947TyrVal: 2.947 ± 1.337
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1019 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski