Amino acid dipepetide frequency for Dishui Lake large algae virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.313AlaAla: 4.313 ± 0.502
1.007AlaCys: 1.007 ± 0.125
3.507AlaAsp: 3.507 ± 0.264
2.915AlaGlu: 2.915 ± 0.226
1.967AlaPhe: 1.967 ± 0.162
3.614AlaGly: 3.614 ± 0.417
1.007AlaHis: 1.007 ± 0.122
4.242AlaIle: 4.242 ± 0.23
3.258AlaLys: 3.258 ± 0.298
4.266AlaLeu: 4.266 ± 0.285
1.351AlaMet: 1.351 ± 0.146
2.938AlaAsn: 2.938 ± 0.197
2.571AlaPro: 2.571 ± 0.295
1.837AlaGln: 1.837 ± 0.173
3.294AlaArg: 3.294 ± 0.327
5.0AlaSer: 5.0 ± 0.432
3.318AlaThr: 3.318 ± 0.577
3.792AlaVal: 3.792 ± 0.226
0.853AlaTrp: 0.853 ± 0.1
2.761AlaTyr: 2.761 ± 0.247
0.0AlaXaa: 0.0 ± 0.0
Cys
0.64CysAla: 0.64 ± 0.108
0.403CysCys: 0.403 ± 0.102
0.865CysAsp: 0.865 ± 0.117
0.746CysGlu: 0.746 ± 0.177
0.675CysPhe: 0.675 ± 0.108
1.315CysGly: 1.315 ± 0.168
0.45CysHis: 0.45 ± 0.079
0.96CysIle: 0.96 ± 0.109
1.351CysLys: 1.351 ± 0.288
1.066CysLeu: 1.066 ± 0.129
0.379CysMet: 0.379 ± 0.074
0.983CysAsn: 0.983 ± 0.131
0.711CysPro: 0.711 ± 0.101
0.581CysGln: 0.581 ± 0.109
0.995CysArg: 0.995 ± 0.151
1.209CysSer: 1.209 ± 0.151
1.066CysThr: 1.066 ± 0.139
0.865CysVal: 0.865 ± 0.102
0.154CysTrp: 0.154 ± 0.041
0.746CysTyr: 0.746 ± 0.106
0.0CysXaa: 0.0 ± 0.0
Asp
3.946AspAla: 3.946 ± 0.34
0.735AspCys: 0.735 ± 0.107
4.277AspAsp: 4.277 ± 0.415
4.04AspGlu: 4.04 ± 0.349
2.026AspPhe: 2.026 ± 0.16
4.443AspGly: 4.443 ± 0.294
1.102AspHis: 1.102 ± 0.146
5.391AspIle: 5.391 ± 0.273
4.42AspLys: 4.42 ± 0.377
4.171AspLeu: 4.171 ± 0.244
2.204AspMet: 2.204 ± 0.179
3.401AspAsn: 3.401 ± 0.2
2.358AspPro: 2.358 ± 0.196
1.398AspGln: 1.398 ± 0.145
2.453AspArg: 2.453 ± 0.219
2.571AspSer: 2.571 ± 0.191
4.218AspThr: 4.218 ± 0.272
4.87AspVal: 4.87 ± 0.307
0.474AspTrp: 0.474 ± 0.073
2.405AspTyr: 2.405 ± 0.197
0.0AspXaa: 0.0 ± 0.0
Glu
3.531GluAla: 3.531 ± 0.303
1.055GluCys: 1.055 ± 0.162
3.294GluAsp: 3.294 ± 0.338
4.1GluGlu: 4.1 ± 0.477
2.038GluPhe: 2.038 ± 0.197
2.784GluGly: 2.784 ± 0.228
1.754GluHis: 1.754 ± 0.191
3.803GluIle: 3.803 ± 0.285
4.965GluLys: 4.965 ± 0.451
5.142GluLeu: 5.142 ± 0.35
1.434GluMet: 1.434 ± 0.127
3.401GluAsn: 3.401 ± 0.252
2.074GluPro: 2.074 ± 0.177
2.239GluGln: 2.239 ± 0.208
3.27GluArg: 3.27 ± 0.255
1.611GluSer: 1.611 ± 0.155
3.045GluThr: 3.045 ± 0.247
2.713GluVal: 2.713 ± 0.201
1.043GluTrp: 1.043 ± 0.132
2.37GluTyr: 2.37 ± 0.194
0.0GluXaa: 0.0 ± 0.0
Phe
2.038PheAla: 2.038 ± 0.194
0.652PheCys: 0.652 ± 0.111
2.346PheAsp: 2.346 ± 0.184
2.145PheGlu: 2.145 ± 0.176
1.564PhePhe: 1.564 ± 0.189
2.299PheGly: 2.299 ± 0.16
0.889PheHis: 0.889 ± 0.119
2.619PheIle: 2.619 ± 0.199
2.239PheLys: 2.239 ± 0.17
2.666PheLeu: 2.666 ± 0.206
1.102PheMet: 1.102 ± 0.106
2.085PheAsn: 2.085 ± 0.162
1.588PhePro: 1.588 ± 0.149
1.303PheGln: 1.303 ± 0.123
1.588PheArg: 1.588 ± 0.136
2.962PheSer: 2.962 ± 0.273
2.429PheThr: 2.429 ± 0.216
2.524PheVal: 2.524 ± 0.202
0.521PheTrp: 0.521 ± 0.094
1.623PheTyr: 1.623 ± 0.128
0.0PheXaa: 0.0 ± 0.0
Gly
3.649GlyAla: 3.649 ± 0.333
1.055GlyCys: 1.055 ± 0.147
3.353GlyAsp: 3.353 ± 0.227
2.619GlyGlu: 2.619 ± 0.236
2.512GlyPhe: 2.512 ± 0.182
4.728GlyGly: 4.728 ± 0.522
1.244GlyHis: 1.244 ± 0.139
5.64GlyIle: 5.64 ± 0.534
3.886GlyLys: 3.886 ± 0.251
4.384GlyLeu: 4.384 ± 0.25
2.062GlyMet: 2.062 ± 0.162
3.898GlyAsn: 3.898 ± 0.515
0.723GlyPro: 0.723 ± 0.113
1.742GlyGln: 1.742 ± 0.172
2.654GlyArg: 2.654 ± 0.19
5.237GlySer: 5.237 ± 0.635
5.273GlyThr: 5.273 ± 1.4
3.638GlyVal: 3.638 ± 0.243
0.652GlyTrp: 0.652 ± 0.091
3.199GlyTyr: 3.199 ± 0.217
0.0GlyXaa: 0.0 ± 0.0
His
1.137HisAla: 1.137 ± 0.137
0.379HisCys: 0.379 ± 0.071
1.149HisAsp: 1.149 ± 0.119
1.386HisGlu: 1.386 ± 0.176
0.723HisPhe: 0.723 ± 0.102
1.552HisGly: 1.552 ± 0.17
0.64HisHis: 0.64 ± 0.096
2.062HisIle: 2.062 ± 0.194
1.505HisLys: 1.505 ± 0.172
1.611HisLeu: 1.611 ± 0.151
0.853HisMet: 0.853 ± 0.093
1.28HisAsn: 1.28 ± 0.135
1.031HisPro: 1.031 ± 0.149
0.711HisGln: 0.711 ± 0.091
1.161HisArg: 1.161 ± 0.138
1.197HisSer: 1.197 ± 0.151
1.611HisThr: 1.611 ± 0.143
1.659HisVal: 1.659 ± 0.132
0.154HisTrp: 0.154 ± 0.05
0.924HisTyr: 0.924 ± 0.128
0.0HisXaa: 0.0 ± 0.0
Ile
4.325IleAla: 4.325 ± 0.202
1.244IleCys: 1.244 ± 0.196
5.19IleAsp: 5.19 ± 0.279
4.502IleGlu: 4.502 ± 0.296
2.393IlePhe: 2.393 ± 0.192
5.498IleGly: 5.498 ± 0.603
2.062IleHis: 2.062 ± 0.174
4.941IleIle: 4.941 ± 0.302
4.514IleLys: 4.514 ± 0.344
5.095IleLeu: 5.095 ± 0.313
2.014IleMet: 2.014 ± 0.18
4.017IleAsn: 4.017 ± 0.332
3.792IlePro: 3.792 ± 0.241
2.63IleGln: 2.63 ± 0.164
3.815IleArg: 3.815 ± 0.24
5.474IleSer: 5.474 ± 0.386
4.396IleThr: 4.396 ± 0.259
4.87IleVal: 4.87 ± 0.272
0.794IleTrp: 0.794 ± 0.096
3.412IleTyr: 3.412 ± 0.299
0.0IleXaa: 0.0 ± 0.0
Lys
3.981LysAla: 3.981 ± 0.297
1.055LysCys: 1.055 ± 0.142
4.645LysAsp: 4.645 ± 0.369
5.213LysGlu: 5.213 ± 0.481
1.588LysPhe: 1.588 ± 0.157
3.152LysGly: 3.152 ± 0.26
1.659LysHis: 1.659 ± 0.185
4.882LysIle: 4.882 ± 0.327
6.979LysLys: 6.979 ± 0.597
5.403LysLeu: 5.403 ± 0.254
1.943LysMet: 1.943 ± 0.193
4.55LysAsn: 4.55 ± 0.32
2.867LysPro: 2.867 ± 0.248
2.322LysGln: 2.322 ± 0.239
3.744LysArg: 3.744 ± 0.304
3.957LysSer: 3.957 ± 0.291
4.218LysThr: 4.218 ± 0.278
3.827LysVal: 3.827 ± 0.24
0.972LysTrp: 0.972 ± 0.117
2.832LysTyr: 2.832 ± 0.301
0.0LysXaa: 0.0 ± 0.0
Leu
4.42LeuAla: 4.42 ± 0.261
1.291LeuCys: 1.291 ± 0.174
5.19LeuAsp: 5.19 ± 0.245
4.206LeuGlu: 4.206 ± 0.274
3.081LeuPhe: 3.081 ± 0.216
4.147LeuGly: 4.147 ± 0.227
1.943LeuHis: 1.943 ± 0.199
4.55LeuIle: 4.55 ± 0.249
5.356LeuLys: 5.356 ± 0.388
6.493LeuLeu: 6.493 ± 0.354
2.287LeuMet: 2.287 ± 0.165
3.566LeuAsn: 3.566 ± 0.197
3.649LeuPro: 3.649 ± 0.246
2.938LeuGln: 2.938 ± 0.178
4.301LeuArg: 4.301 ± 0.244
5.391LeuSer: 5.391 ± 0.332
4.633LeuThr: 4.633 ± 0.3
5.083LeuVal: 5.083 ± 0.296
0.983LeuTrp: 0.983 ± 0.106
4.1LeuTyr: 4.1 ± 0.257
0.0LeuXaa: 0.0 ± 0.0
Met
1.434MetAla: 1.434 ± 0.139
0.45MetCys: 0.45 ± 0.082
1.552MetAsp: 1.552 ± 0.144
1.694MetGlu: 1.694 ± 0.182
1.517MetPhe: 1.517 ± 0.15
1.351MetGly: 1.351 ± 0.165
0.367MetHis: 0.367 ± 0.063
1.991MetIle: 1.991 ± 0.218
2.263MetLys: 2.263 ± 0.199
2.69MetLeu: 2.69 ± 0.193
0.9MetMet: 0.9 ± 0.105
1.422MetAsn: 1.422 ± 0.136
1.754MetPro: 1.754 ± 0.18
0.557MetGln: 0.557 ± 0.092
1.611MetArg: 1.611 ± 0.15
2.239MetSer: 2.239 ± 0.175
1.422MetThr: 1.422 ± 0.133
1.659MetVal: 1.659 ± 0.143
0.438MetTrp: 0.438 ± 0.062
1.635MetTyr: 1.635 ± 0.145
0.0MetXaa: 0.0 ± 0.0
Asn
3.223AsnAla: 3.223 ± 0.251
0.687AsnCys: 0.687 ± 0.097
3.069AsnAsp: 3.069 ± 0.209
2.867AsnGlu: 2.867 ± 0.195
1.837AsnPhe: 1.837 ± 0.176
4.657AsnGly: 4.657 ± 0.411
1.161AsnHis: 1.161 ± 0.152
5.924AsnIle: 5.924 ± 0.551
3.46AsnLys: 3.46 ± 0.275
3.946AsnLeu: 3.946 ± 0.346
1.623AsnMet: 1.623 ± 0.169
3.792AsnAsn: 3.792 ± 0.463
2.796AsnPro: 2.796 ± 0.171
1.647AsnGln: 1.647 ± 0.165
2.773AsnArg: 2.773 ± 0.186
3.803AsnSer: 3.803 ± 0.441
3.993AsnThr: 3.993 ± 0.421
4.325AsnVal: 4.325 ± 0.524
0.486AsnTrp: 0.486 ± 0.08
2.109AsnTyr: 2.109 ± 0.278
0.0AsnXaa: 0.0 ± 0.0
Pro
2.05ProAla: 2.05 ± 0.198
0.64ProCys: 0.64 ± 0.105
3.128ProAsp: 3.128 ± 0.245
2.524ProGlu: 2.524 ± 0.221
1.635ProPhe: 1.635 ± 0.129
1.967ProGly: 1.967 ± 0.189
0.948ProHis: 0.948 ± 0.129
3.081ProIle: 3.081 ± 0.2
2.429ProLys: 2.429 ± 0.202
3.555ProLeu: 3.555 ± 0.236
1.031ProMet: 1.031 ± 0.111
1.919ProAsn: 1.919 ± 0.157
2.192ProPro: 2.192 ± 0.315
1.351ProGln: 1.351 ± 0.173
1.777ProArg: 1.777 ± 0.14
3.306ProSer: 3.306 ± 0.234
2.867ProThr: 2.867 ± 0.225
3.211ProVal: 3.211 ± 0.231
0.438ProTrp: 0.438 ± 0.074
1.979ProTyr: 1.979 ± 0.168
0.0ProXaa: 0.0 ± 0.0
Gln
1.434GlnAla: 1.434 ± 0.129
0.533GlnCys: 0.533 ± 0.098
1.73GlnAsp: 1.73 ± 0.149
1.884GlnGlu: 1.884 ± 0.196
1.327GlnPhe: 1.327 ± 0.132
1.683GlnGly: 1.683 ± 0.174
0.96GlnHis: 0.96 ± 0.137
2.002GlnIle: 2.002 ± 0.156
2.31GlnLys: 2.31 ± 0.195
3.14GlnLeu: 3.14 ± 0.231
0.853GlnMet: 0.853 ± 0.101
1.777GlnAsn: 1.777 ± 0.17
1.363GlnPro: 1.363 ± 0.17
1.872GlnGln: 1.872 ± 0.199
1.446GlnArg: 1.446 ± 0.147
1.979GlnSer: 1.979 ± 0.186
1.813GlnThr: 1.813 ± 0.128
1.825GlnVal: 1.825 ± 0.183
0.521GlnTrp: 0.521 ± 0.088
1.683GlnTyr: 1.683 ± 0.159
0.0GlnXaa: 0.0 ± 0.0
Arg
2.666ArgAla: 2.666 ± 0.211
0.96ArgCys: 0.96 ± 0.164
3.235ArgAsp: 3.235 ± 0.276
3.021ArgGlu: 3.021 ± 0.289
2.192ArgPhe: 2.192 ± 0.194
2.512ArgGly: 2.512 ± 0.204
1.244ArgHis: 1.244 ± 0.117
3.969ArgIle: 3.969 ± 0.284
3.614ArgLys: 3.614 ± 0.307
4.005ArgLeu: 4.005 ± 0.251
1.54ArgMet: 1.54 ± 0.166
2.773ArgAsn: 2.773 ± 0.213
1.754ArgPro: 1.754 ± 0.192
1.505ArgGln: 1.505 ± 0.185
2.536ArgArg: 2.536 ± 0.223
2.974ArgSer: 2.974 ± 0.209
2.204ArgThr: 2.204 ± 0.184
2.867ArgVal: 2.867 ± 0.211
0.936ArgTrp: 0.936 ± 0.141
2.216ArgTyr: 2.216 ± 0.171
0.0ArgXaa: 0.0 ± 0.0
Ser
3.91SerAla: 3.91 ± 0.338
0.972SerCys: 0.972 ± 0.114
3.46SerAsp: 3.46 ± 0.198
2.334SerGlu: 2.334 ± 0.193
2.938SerPhe: 2.938 ± 0.202
4.716SerGly: 4.716 ± 0.813
1.185SerHis: 1.185 ± 0.161
5.391SerIle: 5.391 ± 0.374
4.609SerLys: 4.609 ± 0.284
5.048SerLeu: 5.048 ± 0.249
1.955SerMet: 1.955 ± 0.163
5.865SerAsn: 5.865 ± 1.319
2.761SerPro: 2.761 ± 0.217
2.026SerGln: 2.026 ± 0.207
2.5SerArg: 2.5 ± 0.2
6.138SerSer: 6.138 ± 0.566
4.609SerThr: 4.609 ± 0.326
4.479SerVal: 4.479 ± 0.263
0.581SerTrp: 0.581 ± 0.076
3.401SerTyr: 3.401 ± 0.268
0.0SerXaa: 0.0 ± 0.0
Thr
3.934ThrAla: 3.934 ± 0.757
1.066ThrCys: 1.066 ± 0.121
3.72ThrAsp: 3.72 ± 0.218
3.436ThrGlu: 3.436 ± 0.273
2.074ThrPhe: 2.074 ± 0.217
4.218ThrGly: 4.218 ± 0.561
1.505ThrHis: 1.505 ± 0.141
4.526ThrIle: 4.526 ± 0.446
3.768ThrLys: 3.768 ± 0.33
4.775ThrLeu: 4.775 ± 0.287
1.86ThrMet: 1.86 ± 0.132
3.519ThrAsn: 3.519 ± 0.377
3.033ThrPro: 3.033 ± 0.178
1.967ThrGln: 1.967 ± 0.199
2.82ThrArg: 2.82 ± 0.203
5.249ThrSer: 5.249 ± 0.739
5.32ThrThr: 5.32 ± 1.036
4.147ThrVal: 4.147 ± 0.345
0.723ThrTrp: 0.723 ± 0.183
2.974ThrTyr: 2.974 ± 0.25
0.0ThrXaa: 0.0 ± 0.0
Val
4.123ValAla: 4.123 ± 0.279
1.09ValCys: 1.09 ± 0.137
3.709ValAsp: 3.709 ± 0.233
3.199ValGlu: 3.199 ± 0.241
2.808ValPhe: 2.808 ± 0.18
3.839ValGly: 3.839 ± 0.526
1.623ValHis: 1.623 ± 0.146
4.55ValIle: 4.55 ± 0.257
4.135ValLys: 4.135 ± 0.278
5.545ValLeu: 5.545 ± 0.272
1.73ValMet: 1.73 ± 0.169
3.104ValAsn: 3.104 ± 0.26
2.784ValPro: 2.784 ± 0.182
1.955ValGln: 1.955 ± 0.222
3.258ValArg: 3.258 ± 0.217
4.609ValSer: 4.609 ± 0.362
3.898ValThr: 3.898 ± 0.362
3.78ValVal: 3.78 ± 0.232
0.806ValTrp: 0.806 ± 0.107
3.152ValTyr: 3.152 ± 0.201
0.0ValXaa: 0.0 ± 0.0
Trp
0.675TrpAla: 0.675 ± 0.172
0.308TrpCys: 0.308 ± 0.067
0.818TrpAsp: 0.818 ± 0.097
0.616TrpGlu: 0.616 ± 0.081
0.367TrpPhe: 0.367 ± 0.082
0.64TrpGly: 0.64 ± 0.091
0.19TrpHis: 0.19 ± 0.052
1.007TrpIle: 1.007 ± 0.128
0.995TrpLys: 0.995 ± 0.111
1.043TrpLeu: 1.043 ± 0.138
0.462TrpMet: 0.462 ± 0.075
0.675TrpAsn: 0.675 ± 0.081
0.391TrpPro: 0.391 ± 0.069
0.32TrpGln: 0.32 ± 0.059
0.616TrpArg: 0.616 ± 0.09
0.77TrpSer: 0.77 ± 0.115
0.841TrpThr: 0.841 ± 0.13
0.758TrpVal: 0.758 ± 0.077
0.095TrpTrp: 0.095 ± 0.028
0.427TrpTyr: 0.427 ± 0.071
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.393TyrAla: 2.393 ± 0.185
0.581TyrCys: 0.581 ± 0.108
2.666TyrAsp: 2.666 ± 0.231
2.216TyrGlu: 2.216 ± 0.196
1.919TyrPhe: 1.919 ± 0.163
3.033TyrGly: 3.033 ± 0.279
0.794TyrHis: 0.794 ± 0.109
3.448TyrIle: 3.448 ± 0.24
3.732TyrLys: 3.732 ± 0.258
3.566TyrLeu: 3.566 ± 0.262
1.351TyrMet: 1.351 ± 0.137
3.211TyrAsn: 3.211 ± 0.227
1.837TyrPro: 1.837 ± 0.143
1.232TyrGln: 1.232 ± 0.19
2.109TyrArg: 2.109 ± 0.217
3.199TyrSer: 3.199 ± 0.281
3.46TyrThr: 3.46 ± 0.256
2.808TyrVal: 2.808 ± 0.179
0.391TyrTrp: 0.391 ± 0.065
1.86TyrTyr: 1.86 ± 0.166
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 208 proteins (84399 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski