Amino acid dipepetide frequency for Gallaecimonas xiamenensis 3-C-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.926AlaAla: 11.926 ± 0.147	1.06AlaCys: 1.06 ± 0.038	6.063AlaAsp: 6.063 ± 0.092	6.356AlaGlu: 6.356 ± 0.094	3.995AlaPhe: 3.995 ± 0.065	8.721AlaGly: 8.721 ± 0.095	1.867AlaHis: 1.867 ± 0.038	5.261AlaIle: 5.261 ± 0.072	5.271AlaLys: 5.271 ± 0.086	15.545AlaLeu: 15.545 ± 0.172	3.299AlaMet: 3.299 ± 0.051	3.21AlaAsn: 3.21 ± 0.063	4.677AlaPro: 4.677 ± 0.073	5.706AlaGln: 5.706 ± 0.084	5.893AlaArg: 5.893 ± 0.081	6.124AlaSer: 6.124 ± 0.083	4.726AlaThr: 4.726 ± 0.061	7.104AlaVal: 7.104 ± 0.081	1.577AlaTrp: 1.577 ± 0.039	2.496AlaTyr: 2.496 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	0.834CysAla: 0.834 ± 0.032	0.134CysCys: 0.134 ± 0.011	0.523CysAsp: 0.523 ± 0.033	0.412CysGlu: 0.412 ± 0.017	0.374CysPhe: 0.374 ± 0.017	0.831CysGly: 0.831 ± 0.027	0.294CysHis: 0.294 ± 0.015	0.395CysIle: 0.395 ± 0.017	0.249CysLys: 0.249 ± 0.016	1.122CysLeu: 1.122 ± 0.028	0.169CysMet: 0.169 ± 0.011	0.267CysAsn: 0.267 ± 0.016	0.536CysPro: 0.536 ± 0.033	0.642CysGln: 0.642 ± 0.034	0.618CysArg: 0.618 ± 0.026	0.539CysSer: 0.539 ± 0.021	0.444CysThr: 0.444 ± 0.018	0.491CysVal: 0.491 ± 0.02	0.149CysTrp: 0.149 ± 0.011	0.319CysTyr: 0.319 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	5.956AspAla: 5.956 ± 0.078	0.503AspCys: 0.503 ± 0.018	3.451AspAsp: 3.451 ± 0.074	3.292AspGlu: 3.292 ± 0.054	2.549AspPhe: 2.549 ± 0.05	5.122AspGly: 5.122 ± 0.128	1.148AspHis: 1.148 ± 0.034	2.941AspIle: 2.941 ± 0.052	3.065AspLys: 3.065 ± 0.051	6.126AspLeu: 6.126 ± 0.073	1.37AspMet: 1.37 ± 0.032	2.249AspAsn: 2.249 ± 0.065	2.872AspPro: 2.872 ± 0.045	2.787AspGln: 2.787 ± 0.06	2.966AspArg: 2.966 ± 0.048	3.452AspSer: 3.452 ± 0.06	2.597AspThr: 2.597 ± 0.057	3.24AspVal: 3.24 ± 0.057	1.206AspTrp: 1.206 ± 0.034	1.897AspTyr: 1.897 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.468GluAla: 6.468 ± 0.091	0.323GluCys: 0.323 ± 0.017	2.787GluAsp: 2.787 ± 0.055	3.243GluGlu: 3.243 ± 0.074	1.503GluPhe: 1.503 ± 0.035	4.018GluGly: 4.018 ± 0.062	1.232GluHis: 1.232 ± 0.034	2.169GluIle: 2.169 ± 0.046	2.391GluLys: 2.391 ± 0.053	6.821GluLeu: 6.821 ± 0.095	1.192GluMet: 1.192 ± 0.037	1.436GluAsn: 1.436 ± 0.03	2.304GluPro: 2.304 ± 0.043	3.406GluGln: 3.406 ± 0.065	3.756GluArg: 3.756 ± 0.074	2.502GluSer: 2.502 ± 0.045	2.088GluThr: 2.088 ± 0.043	4.127GluVal: 4.127 ± 0.066	0.505GluTrp: 0.505 ± 0.021	1.05GluTyr: 1.05 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.997PheAla: 3.997 ± 0.06	0.447PheCys: 0.447 ± 0.018	2.764PheAsp: 2.764 ± 0.06	2.203PheGlu: 2.203 ± 0.044	1.566PhePhe: 1.566 ± 0.044	3.305PheGly: 3.305 ± 0.06	0.72PheHis: 0.72 ± 0.027	1.712PheIle: 1.712 ± 0.044	1.587PheLys: 1.587 ± 0.035	3.333PheLeu: 3.333 ± 0.058	0.859PheMet: 0.859 ± 0.028	1.478PheAsn: 1.478 ± 0.034	1.378PhePro: 1.378 ± 0.034	1.255PheGln: 1.255 ± 0.034	1.675PheArg: 1.675 ± 0.038	2.565PheSer: 2.565 ± 0.045	1.93PheThr: 1.93 ± 0.044	2.424PheVal: 2.424 ± 0.052	0.642PheTrp: 0.642 ± 0.025	1.193PheTyr: 1.193 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	7.468GlyAla: 7.468 ± 0.097	0.869GlyCys: 0.869 ± 0.026	4.71GlyAsp: 4.71 ± 0.098	4.57GlyGlu: 4.57 ± 0.064	3.458GlyPhe: 3.458 ± 0.056	5.972GlyGly: 5.972 ± 0.084	1.955GlyHis: 1.955 ± 0.049	4.007GlyIle: 4.007 ± 0.07	3.738GlyLys: 3.738 ± 0.06	9.775GlyLeu: 9.775 ± 0.102	1.948GlyMet: 1.948 ± 0.039	2.513GlyAsn: 2.513 ± 0.057	2.937GlyPro: 2.937 ± 0.055	4.972GlyGln: 4.972 ± 0.075	4.65GlyArg: 4.65 ± 0.066	4.601GlySer: 4.601 ± 0.076	3.789GlyThr: 3.789 ± 0.06	5.41GlyVal: 5.41 ± 0.075	1.338GlyTrp: 1.338 ± 0.037	2.538GlyTyr: 2.538 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.485HisAla: 1.485 ± 0.033	0.355HisCys: 0.355 ± 0.017	0.968HisAsp: 0.968 ± 0.029	0.839HisGlu: 0.839 ± 0.029	1.132HisPhe: 1.132 ± 0.033	1.744HisGly: 1.744 ± 0.04	0.707HisHis: 0.707 ± 0.025	0.982HisIle: 0.982 ± 0.028	0.83HisLys: 0.83 ± 0.026	2.678HisLeu: 2.678 ± 0.049	0.473HisMet: 0.473 ± 0.02	0.682HisAsn: 0.682 ± 0.022	1.365HisPro: 1.365 ± 0.035	1.467HisGln: 1.467 ± 0.034	1.281HisArg: 1.281 ± 0.039	1.296HisSer: 1.296 ± 0.032	0.762HisThr: 0.762 ± 0.027	0.955HisVal: 0.955 ± 0.031	0.557HisTrp: 0.557 ± 0.025	0.932HisTyr: 0.932 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	4.815IleAla: 4.815 ± 0.067	0.455IleCys: 0.455 ± 0.019	3.013IleAsp: 3.013 ± 0.052	2.7IleGlu: 2.7 ± 0.054	1.409IlePhe: 1.409 ± 0.037	3.555IleGly: 3.555 ± 0.07	0.888IleHis: 0.888 ± 0.026	1.928IleIle: 1.928 ± 0.048	2.164IleLys: 2.164 ± 0.051	3.793IleLeu: 3.793 ± 0.057	0.777IleMet: 0.777 ± 0.026	1.797IleAsn: 1.797 ± 0.044	1.981IlePro: 1.981 ± 0.05	1.607IleGln: 1.607 ± 0.037	2.438IleArg: 2.438 ± 0.052	2.78IleSer: 2.78 ± 0.052	2.339IleThr: 2.339 ± 0.046	2.394IleVal: 2.394 ± 0.051	0.515IleTrp: 0.515 ± 0.021	1.173IleTyr: 1.173 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	6.228LysAla: 6.228 ± 0.086	0.207LysCys: 0.207 ± 0.015	2.838LysAsp: 2.838 ± 0.058	2.397LysGlu: 2.397 ± 0.05	0.885LysPhe: 0.885 ± 0.03	3.886LysGly: 3.886 ± 0.068	0.8LysHis: 0.8 ± 0.025	1.458LysIle: 1.458 ± 0.039	1.732LysLys: 1.732 ± 0.047	4.413LysLeu: 4.413 ± 0.071	0.816LysMet: 0.816 ± 0.028	1.031LysAsn: 1.031 ± 0.033	2.127LysPro: 2.127 ± 0.043	1.469LysGln: 1.469 ± 0.04	2.369LysArg: 2.369 ± 0.044	1.923LysSer: 1.923 ± 0.045	2.009LysThr: 2.009 ± 0.04	3.753LysVal: 3.753 ± 0.057	0.419LysTrp: 0.419 ± 0.016	0.779LysTyr: 0.779 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	17.358LeuAla: 17.358 ± 0.183	1.271LeuCys: 1.271 ± 0.035	7.574LeuAsp: 7.574 ± 0.08	6.042LeuGlu: 6.042 ± 0.087	4.198LeuPhe: 4.198 ± 0.061	10.411LeuGly: 10.411 ± 0.109	2.23LeuHis: 2.23 ± 0.049	4.428LeuIle: 4.428 ± 0.07	5.234LeuLys: 5.234 ± 0.071	14.22LeuLeu: 14.22 ± 0.181	2.921LeuMet: 2.921 ± 0.056	3.408LeuAsn: 3.408 ± 0.052	6.359LeuPro: 6.359 ± 0.092	3.844LeuGln: 3.844 ± 0.063	5.743LeuArg: 5.743 ± 0.087	7.597LeuSer: 7.597 ± 0.095	6.147LeuThr: 6.147 ± 0.073	9.518LeuVal: 9.518 ± 0.112	1.788LeuTrp: 1.788 ± 0.046	2.929LeuTyr: 2.929 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	3.161MetAla: 3.161 ± 0.048	0.098MetCys: 0.098 ± 0.008	1.361MetAsp: 1.361 ± 0.035	1.191MetGlu: 1.191 ± 0.03	0.559MetPhe: 0.559 ± 0.019	1.792MetGly: 1.792 ± 0.036	0.412MetHis: 0.412 ± 0.021	0.8MetIle: 0.8 ± 0.029	1.106MetLys: 1.106 ± 0.033	2.671MetLeu: 2.671 ± 0.046	0.613MetMet: 0.613 ± 0.025	0.711MetAsn: 0.711 ± 0.025	1.144MetPro: 1.144 ± 0.028	0.956MetGln: 0.956 ± 0.027	1.16MetArg: 1.16 ± 0.028	1.46MetSer: 1.46 ± 0.032	1.465MetThr: 1.465 ± 0.034	1.782MetVal: 1.782 ± 0.037	0.179MetTrp: 0.179 ± 0.013	0.355MetTyr: 0.355 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.934AsnAla: 2.934 ± 0.054	0.336AsnCys: 0.336 ± 0.038	1.74AsnAsp: 1.74 ± 0.043	1.305AsnGlu: 1.305 ± 0.037	1.04AsnPhe: 1.04 ± 0.037	2.639AsnGly: 2.639 ± 0.056	0.681AsnHis: 0.681 ± 0.024	1.434AsnIle: 1.434 ± 0.036	1.184AsnLys: 1.184 ± 0.03	3.559AsnLeu: 3.559 ± 0.06	0.602AsnMet: 0.602 ± 0.024	1.059AsnAsn: 1.059 ± 0.034	1.942AsnPro: 1.942 ± 0.041	1.529AsnGln: 1.529 ± 0.037	1.761AsnArg: 1.761 ± 0.042	1.667AsnSer: 1.667 ± 0.04	1.457AsnThr: 1.457 ± 0.036	1.67AsnVal: 1.67 ± 0.037	0.558AsnTrp: 0.558 ± 0.025	0.928AsnTyr: 0.928 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	5.392ProAla: 5.392 ± 0.079	0.373ProCys: 0.373 ± 0.02	2.942ProAsp: 2.942 ± 0.055	2.852ProGlu: 2.852 ± 0.043	1.871ProPhe: 1.871 ± 0.038	4.005ProGly: 4.005 ± 0.066	0.953ProHis: 0.953 ± 0.031	1.763ProIle: 1.763 ± 0.043	2.08ProLys: 2.08 ± 0.035	5.915ProLeu: 5.915 ± 0.076	1.133ProMet: 1.133 ± 0.031	1.302ProAsn: 1.302 ± 0.031	1.706ProPro: 1.706 ± 0.038	2.459ProGln: 2.459 ± 0.048	2.092ProArg: 2.092 ± 0.048	2.584ProSer: 2.584 ± 0.048	1.755ProThr: 1.755 ± 0.05	3.627ProVal: 3.627 ± 0.058	0.875ProTrp: 0.875 ± 0.027	1.373ProTyr: 1.373 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	6.625GlnAla: 6.625 ± 0.092	0.451GlnCys: 0.451 ± 0.021	2.576GlnAsp: 2.576 ± 0.051	2.331GlnGlu: 2.331 ± 0.048	1.564GlnPhe: 1.564 ± 0.039	5.026GlnGly: 5.026 ± 0.07	1.147GlnHis: 1.147 ± 0.035	1.716GlnIle: 1.716 ± 0.036	1.593GlnLys: 1.593 ± 0.036	6.34GlnLeu: 6.34 ± 0.079	1.106GlnMet: 1.106 ± 0.032	1.09GlnAsn: 1.09 ± 0.03	2.432GlnPro: 2.432 ± 0.046	3.439GlnGln: 3.439 ± 0.083	2.872GlnArg: 2.872 ± 0.055	2.861GlnSer: 2.861 ± 0.055	1.9GlnThr: 1.9 ± 0.044	3.854GlnVal: 3.854 ± 0.053	0.975GlnTrp: 0.975 ± 0.032	1.468GlnTyr: 1.468 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	4.722ArgAla: 4.722 ± 0.068	0.511ArgCys: 0.511 ± 0.02	3.071ArgAsp: 3.071 ± 0.055	2.862ArgGlu: 2.862 ± 0.059	2.914ArgPhe: 2.914 ± 0.062	3.263ArgGly: 3.263 ± 0.055	1.756ArgHis: 1.756 ± 0.04	2.758ArgIle: 2.758 ± 0.053	1.81ArgLys: 1.81 ± 0.046	7.745ArgLeu: 7.745 ± 0.108	1.187ArgMet: 1.187 ± 0.027	1.535ArgAsn: 1.535 ± 0.033	2.407ArgPro: 2.407 ± 0.04	3.867ArgGln: 3.867 ± 0.068	3.702ArgArg: 3.702 ± 0.06	2.682ArgSer: 2.682 ± 0.042	2.207ArgThr: 2.207 ± 0.042	3.43ArgVal: 3.43 ± 0.058	1.007ArgTrp: 1.007 ± 0.028	2.181ArgTyr: 2.181 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	5.728SerAla: 5.728 ± 0.071	0.536SerCys: 0.536 ± 0.023	3.315SerAsp: 3.315 ± 0.06	2.807SerGlu: 2.807 ± 0.049	2.329SerPhe: 2.329 ± 0.046	4.895SerGly: 4.895 ± 0.075	1.433SerHis: 1.433 ± 0.036	2.291SerIle: 2.291 ± 0.051	1.894SerLys: 1.894 ± 0.04	7.595SerLeu: 7.595 ± 0.099	1.102SerMet: 1.102 ± 0.031	1.654SerAsn: 1.654 ± 0.048	2.988SerPro: 2.988 ± 0.053	3.122SerGln: 3.122 ± 0.056	3.438SerArg: 3.438 ± 0.053	3.167SerSer: 3.167 ± 0.069	2.49SerThr: 2.49 ± 0.046	3.441SerVal: 3.441 ± 0.057	0.931SerTrp: 0.931 ± 0.028	1.712SerTyr: 1.712 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	4.517ThrAla: 4.517 ± 0.068	0.314ThrCys: 0.314 ± 0.017	2.796ThrAsp: 2.796 ± 0.059	2.406ThrGlu: 2.406 ± 0.048	1.698ThrPhe: 1.698 ± 0.043	4.136ThrGly: 4.136 ± 0.062	0.841ThrHis: 0.841 ± 0.028	1.871ThrIle: 1.871 ± 0.049	1.448ThrLys: 1.448 ± 0.04	7.034ThrLeu: 7.034 ± 0.089	0.824ThrMet: 0.824 ± 0.029	1.212ThrAsn: 1.212 ± 0.032	2.553ThrPro: 2.553 ± 0.046	2.371ThrGln: 2.371 ± 0.047	2.326ThrArg: 2.326 ± 0.048	2.359ThrSer: 2.359 ± 0.048	2.077ThrThr: 2.077 ± 0.048	3.278ThrVal: 3.278 ± 0.059	0.601ThrTrp: 0.601 ± 0.021	1.075ThrTyr: 1.075 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.908ValAla: 7.908 ± 0.082	0.598ValCys: 0.598 ± 0.022	4.059ValAsp: 4.059 ± 0.062	3.889ValGlu: 3.889 ± 0.055	2.292ValPhe: 2.292 ± 0.046	4.606ValGly: 4.606 ± 0.064	1.261ValHis: 1.261 ± 0.036	3.19ValIle: 3.19 ± 0.057	2.983ValLys: 2.983 ± 0.055	8.235ValLeu: 8.235 ± 0.093	1.795ValMet: 1.795 ± 0.041	2.255ValAsn: 2.255 ± 0.046	3.154ValPro: 3.154 ± 0.056	2.758ValGln: 2.758 ± 0.048	3.72ValArg: 3.72 ± 0.059	4.333ValSer: 4.333 ± 0.056	3.92ValThr: 3.92 ± 0.065	5.365ValVal: 5.365 ± 0.082	0.721ValTrp: 0.721 ± 0.028	1.464ValTyr: 1.464 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.191TrpAla: 1.191 ± 0.032	0.176TrpCys: 0.176 ± 0.014	0.74TrpAsp: 0.74 ± 0.027	0.519TrpGlu: 0.519 ± 0.022	0.554TrpPhe: 0.554 ± 0.019	0.963TrpGly: 0.963 ± 0.029	0.48TrpHis: 0.48 ± 0.022	0.456TrpIle: 0.456 ± 0.02	0.311TrpLys: 0.311 ± 0.019	2.727TrpLeu: 2.727 ± 0.064	0.313TrpMet: 0.313 ± 0.017	0.347TrpAsn: 0.347 ± 0.016	0.789TrpPro: 0.789 ± 0.028	1.605TrpGln: 1.605 ± 0.043	1.071TrpArg: 1.071 ± 0.034	0.712TrpSer: 0.712 ± 0.025	0.618TrpThr: 0.618 ± 0.021	1.085TrpVal: 1.085 ± 0.028	0.27TrpTrp: 0.27 ± 0.016	0.4TrpTyr: 0.4 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.167TyrAla: 2.167 ± 0.047	0.327TyrCys: 0.327 ± 0.016	1.498TyrAsp: 1.498 ± 0.046	1.103TyrGlu: 1.103 ± 0.033	1.142TyrPhe: 1.142 ± 0.032	2.326TyrGly: 2.326 ± 0.049	0.682TyrHis: 0.682 ± 0.027	0.96TyrIle: 0.96 ± 0.034	0.868TyrLys: 0.868 ± 0.035	3.573TyrLeu: 3.573 ± 0.061	0.481TyrMet: 0.481 ± 0.018	0.786TyrAsn: 0.786 ± 0.027	1.403TyrPro: 1.403 ± 0.029	2.105TyrGln: 2.105 ± 0.046	2.087TyrArg: 2.087 ± 0.051	1.665TyrSer: 1.665 ± 0.043	1.017TyrThr: 1.017 ± 0.032	1.558TyrVal: 1.558 ± 0.036	0.514TyrTrp: 0.514 ± 0.021	0.91TyrTyr: 0.91 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3798 proteins (1224611 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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