Amino acid dipepetide frequency for Sweet potato leaf curl virus-Spain

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.656AlaAla: 2.656 ± 1.741
0.0AlaCys: 0.0 ± 0.0
2.656AlaAsp: 2.656 ± 3.358
5.312AlaGlu: 5.312 ± 3.642
2.656AlaPhe: 2.656 ± 1.652
0.0AlaGly: 0.0 ± 0.0
0.0AlaHis: 0.0 ± 0.0
2.656AlaIle: 2.656 ± 1.253
6.64AlaLys: 6.64 ± 2.949
7.968AlaLeu: 7.968 ± 3.378
0.0AlaMet: 0.0 ± 0.0
3.984AlaAsn: 3.984 ± 1.768
2.656AlaPro: 2.656 ± 1.652
3.984AlaGln: 3.984 ± 3.008
1.328AlaArg: 1.328 ± 0.916
1.328AlaSer: 1.328 ± 0.916
0.0AlaThr: 0.0 ± 0.0
1.328AlaVal: 1.328 ± 0.916
0.0AlaTrp: 0.0 ± 0.0
1.328AlaTyr: 1.328 ± 0.916
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
2.656CysCys: 2.656 ± 2.428
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.328CysPhe: 1.328 ± 1.272
2.656CysGly: 2.656 ± 2.543
1.328CysHis: 1.328 ± 1.679
0.0CysIle: 0.0 ± 0.0
2.656CysLys: 2.656 ± 1.253
1.328CysLeu: 1.328 ± 1.679
1.328CysMet: 1.328 ± 1.214
2.656CysAsn: 2.656 ± 2.713
5.312CysPro: 5.312 ± 3.642
0.0CysGln: 0.0 ± 0.0
1.328CysArg: 1.328 ± 0.916
5.312CysSer: 5.312 ± 2.641
2.656CysThr: 2.656 ± 2.543
3.984CysVal: 3.984 ± 2.748
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
2.656AspCys: 2.656 ± 1.652
3.984AspAsp: 3.984 ± 1.212
2.656AspGlu: 2.656 ± 1.597
1.328AspPhe: 1.328 ± 0.916
1.328AspGly: 1.328 ± 0.916
1.328AspHis: 1.328 ± 0.916
1.328AspIle: 1.328 ± 0.916
0.0AspLys: 0.0 ± 0.0
2.656AspLeu: 2.656 ± 1.741
0.0AspMet: 0.0 ± 0.0
2.656AspAsn: 2.656 ± 1.832
3.984AspPro: 3.984 ± 1.398
0.0AspGln: 0.0 ± 0.0
5.312AspArg: 5.312 ± 2.717
6.64AspSer: 6.64 ± 1.097
3.984AspThr: 3.984 ± 2.786
2.656AspVal: 2.656 ± 1.211
1.328AspTrp: 1.328 ± 1.272
2.656AspTyr: 2.656 ± 1.253
0.0AspXaa: 0.0 ± 0.0
Glu
3.984GluAla: 3.984 ± 1.398
2.656GluCys: 2.656 ± 1.597
0.0GluAsp: 0.0 ± 0.0
5.312GluGlu: 5.312 ± 1.645
2.656GluPhe: 2.656 ± 1.211
2.656GluGly: 2.656 ± 1.597
0.0GluHis: 0.0 ± 0.0
1.328GluIle: 1.328 ± 1.214
1.328GluLys: 1.328 ± 1.214
7.968GluLeu: 7.968 ± 4.736
0.0GluMet: 0.0 ± 0.0
5.312GluAsn: 5.312 ± 2.505
3.984GluPro: 3.984 ± 1.398
1.328GluGln: 1.328 ± 0.916
2.656GluArg: 2.656 ± 2.713
5.312GluSer: 5.312 ± 3.304
2.656GluThr: 2.656 ± 1.328
2.656GluVal: 2.656 ± 2.023
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.328PheAla: 1.328 ± 1.214
0.0PheCys: 0.0 ± 0.0
1.328PheAsp: 1.328 ± 1.356
2.656PheGlu: 2.656 ± 1.328
2.656PhePhe: 2.656 ± 1.211
1.328PheGly: 1.328 ± 1.272
3.984PheHis: 3.984 ± 2.403
1.328PheIle: 1.328 ± 1.272
3.984PheLys: 3.984 ± 1.932
1.328PheLeu: 1.328 ± 1.356
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.0PhePro: 0.0 ± 0.0
2.656PheGln: 2.656 ± 1.667
3.984PheArg: 3.984 ± 2.582
3.984PheSer: 3.984 ± 1.212
5.312PheThr: 5.312 ± 1.95
2.656PheVal: 2.656 ± 1.832
0.0PheTrp: 0.0 ± 0.0
2.656PheTyr: 2.656 ± 1.211
0.0PheXaa: 0.0 ± 0.0
Gly
1.328GlyAla: 1.328 ± 1.356
3.984GlyCys: 3.984 ± 2.352
1.328GlyAsp: 1.328 ± 0.916
5.312GlyGlu: 5.312 ± 2.59
7.968GlyPhe: 7.968 ± 3.994
2.656GlyGly: 2.656 ± 1.832
0.0GlyHis: 0.0 ± 0.0
9.296GlyIle: 9.296 ± 2.811
3.984GlyLys: 3.984 ± 1.932
2.656GlyLeu: 2.656 ± 1.832
1.328GlyMet: 1.328 ± 1.101
2.656GlyAsn: 2.656 ± 1.741
2.656GlyPro: 2.656 ± 1.832
1.328GlyGln: 1.328 ± 1.272
6.64GlyArg: 6.64 ± 2.51
1.328GlySer: 1.328 ± 1.272
6.64GlyThr: 6.64 ± 2.361
2.656GlyVal: 2.656 ± 1.741
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.328HisAla: 1.328 ± 1.272
0.0HisCys: 0.0 ± 0.0
1.328HisAsp: 1.328 ± 0.916
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.328HisGly: 1.328 ± 1.272
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
3.984HisLys: 3.984 ± 1.665
2.656HisLeu: 2.656 ± 1.211
0.0HisMet: 0.0 ± 0.0
1.328HisAsn: 1.328 ± 0.916
2.656HisPro: 2.656 ± 1.741
3.984HisGln: 3.984 ± 2.618
3.984HisArg: 3.984 ± 1.673
1.328HisSer: 1.328 ± 1.356
2.656HisThr: 2.656 ± 1.832
2.656HisVal: 2.656 ± 1.253
1.328HisTrp: 1.328 ± 1.214
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.984IleAla: 3.984 ± 1.759
1.328IleCys: 1.328 ± 1.356
3.984IleAsp: 3.984 ± 1.665
1.328IleGlu: 1.328 ± 1.356
2.656IlePhe: 2.656 ± 1.667
1.328IleGly: 1.328 ± 1.356
0.0IleHis: 0.0 ± 0.0
2.656IleIle: 2.656 ± 1.211
2.656IleLys: 2.656 ± 1.652
3.984IleLeu: 3.984 ± 1.768
0.0IleMet: 0.0 ± 0.0
2.656IleAsn: 2.656 ± 1.211
7.968IlePro: 7.968 ± 3.356
2.656IleGln: 2.656 ± 2.543
7.968IleArg: 7.968 ± 0.668
1.328IleSer: 1.328 ± 1.214
3.984IleThr: 3.984 ± 2.352
3.984IleVal: 3.984 ± 1.212
0.0IleTrp: 0.0 ± 0.0
1.328IleTyr: 1.328 ± 1.356
0.0IleXaa: 0.0 ± 0.0
Lys
3.984LysAla: 3.984 ± 2.618
1.328LysCys: 1.328 ± 1.272
1.328LysAsp: 1.328 ± 0.916
3.984LysGlu: 3.984 ± 1.932
3.984LysPhe: 3.984 ± 1.665
3.984LysGly: 3.984 ± 1.789
0.0LysHis: 0.0 ± 0.0
3.984LysIle: 3.984 ± 1.665
3.984LysLys: 3.984 ± 1.398
1.328LysLeu: 1.328 ± 1.214
1.328LysMet: 1.328 ± 0.916
0.0LysAsn: 0.0 ± 0.0
0.0LysPro: 0.0 ± 0.0
0.0LysGln: 0.0 ± 0.0
7.968LysArg: 7.968 ± 2.729
2.656LysSer: 2.656 ± 1.253
1.328LysThr: 1.328 ± 1.214
3.984LysVal: 3.984 ± 2.219
1.328LysTrp: 1.328 ± 1.356
5.312LysTyr: 5.312 ± 2.299
0.0LysXaa: 0.0 ± 0.0
Leu
1.328LeuAla: 1.328 ± 1.356
5.312LeuCys: 5.312 ± 3.75
1.328LeuAsp: 1.328 ± 1.272
5.312LeuGlu: 5.312 ± 2.614
1.328LeuPhe: 1.328 ± 1.214
3.984LeuGly: 3.984 ± 1.363
2.656LeuHis: 2.656 ± 1.597
5.312LeuIle: 5.312 ± 1.645
3.984LeuLys: 3.984 ± 1.363
3.984LeuLeu: 3.984 ± 3.462
2.656LeuMet: 2.656 ± 1.741
3.984LeuAsn: 3.984 ± 2.219
5.312LeuPro: 5.312 ± 2.59
5.312LeuGln: 5.312 ± 2.544
6.64LeuArg: 6.64 ± 1.089
2.656LeuSer: 2.656 ± 1.667
5.312LeuThr: 5.312 ± 3.219
2.656LeuVal: 2.656 ± 1.211
2.656LeuTrp: 2.656 ± 2.428
5.312LeuTyr: 5.312 ± 1.616
0.0LeuXaa: 0.0 ± 0.0
Met
1.328MetAla: 1.328 ± 1.214
1.328MetCys: 1.328 ± 1.679
5.312MetAsp: 5.312 ± 2.399
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
2.656MetGly: 2.656 ± 1.741
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.328MetLys: 1.328 ± 0.916
3.984MetLeu: 3.984 ± 2.375
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
1.328MetGln: 1.328 ± 0.916
2.656MetArg: 2.656 ± 2.713
3.984MetSer: 3.984 ± 2.005
2.656MetThr: 2.656 ± 1.741
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.328MetTyr: 1.328 ± 0.916
0.0MetXaa: 0.0 ± 0.0
Asn
2.656AsnAla: 2.656 ± 1.832
1.328AsnCys: 1.328 ± 1.214
1.328AsnAsp: 1.328 ± 1.356
2.656AsnGlu: 2.656 ± 1.211
2.656AsnPhe: 2.656 ± 1.832
0.0AsnGly: 0.0 ± 0.0
6.64AsnHis: 6.64 ± 2.547
3.984AsnIle: 3.984 ± 1.212
1.328AsnLys: 1.328 ± 0.916
5.312AsnLeu: 5.312 ± 2.679
1.328AsnMet: 1.328 ± 0.911
2.656AsnAsn: 2.656 ± 1.253
3.984AsnPro: 3.984 ± 1.363
0.0AsnGln: 0.0 ± 0.0
0.0AsnArg: 0.0 ± 0.0
5.312AsnSer: 5.312 ± 3.216
0.0AsnThr: 0.0 ± 0.0
1.328AsnVal: 1.328 ± 0.916
1.328AsnTrp: 1.328 ± 1.272
1.328AsnTyr: 1.328 ± 1.356
0.0AsnXaa: 0.0 ± 0.0
Pro
2.656ProAla: 2.656 ± 2.543
1.328ProCys: 1.328 ± 0.916
3.984ProAsp: 3.984 ± 2.536
3.984ProGlu: 3.984 ± 2.618
1.328ProPhe: 1.328 ± 1.356
5.312ProGly: 5.312 ± 2.595
2.656ProHis: 2.656 ± 1.253
2.656ProIle: 2.656 ± 1.253
2.656ProLys: 2.656 ± 1.328
5.312ProLeu: 5.312 ± 2.299
3.984ProMet: 3.984 ± 3.128
2.656ProAsn: 2.656 ± 1.328
1.328ProPro: 1.328 ± 1.272
3.984ProGln: 3.984 ± 3.312
0.0ProArg: 0.0 ± 0.0
3.984ProSer: 3.984 ± 1.905
3.984ProThr: 3.984 ± 3.296
5.312ProVal: 5.312 ± 3.665
0.0ProTrp: 0.0 ± 0.0
3.984ProTyr: 3.984 ± 2.748
0.0ProXaa: 0.0 ± 0.0
Gln
1.328GlnAla: 1.328 ± 0.916
0.0GlnCys: 0.0 ± 0.0
2.656GlnAsp: 2.656 ± 1.253
1.328GlnGlu: 1.328 ± 1.272
1.328GlnPhe: 1.328 ± 1.356
5.312GlnGly: 5.312 ± 1.908
1.328GlnHis: 1.328 ± 1.272
2.656GlnIle: 2.656 ± 1.863
0.0GlnLys: 0.0 ± 0.0
2.656GlnLeu: 2.656 ± 2.543
1.328GlnMet: 1.328 ± 1.356
2.656GlnAsn: 2.656 ± 1.597
2.656GlnPro: 2.656 ± 1.863
0.0GlnGln: 0.0 ± 0.0
1.328GlnArg: 1.328 ± 1.679
2.656GlnSer: 2.656 ± 1.667
3.984GlnThr: 3.984 ± 1.212
2.656GlnVal: 2.656 ± 1.832
0.0GlnTrp: 0.0 ± 0.0
1.328GlnTyr: 1.328 ± 1.214
0.0GlnXaa: 0.0 ± 0.0
Arg
6.64ArgAla: 6.64 ± 2.904
2.656ArgCys: 2.656 ± 1.328
3.984ArgAsp: 3.984 ± 1.932
2.656ArgGlu: 2.656 ± 2.023
2.656ArgPhe: 2.656 ± 1.328
5.312ArgGly: 5.312 ± 2.551
2.656ArgHis: 2.656 ± 1.652
10.624ArgIle: 10.624 ± 2.98
5.312ArgLys: 5.312 ± 2.505
7.968ArgLeu: 7.968 ± 3.518
3.984ArgMet: 3.984 ± 2.748
0.0ArgAsn: 0.0 ± 0.0
9.296ArgPro: 9.296 ± 3.091
1.328ArgGln: 1.328 ± 1.214
6.64ArgArg: 6.64 ± 3.565
2.656ArgSer: 2.656 ± 1.741
6.64ArgThr: 6.64 ± 4.019
5.312ArgVal: 5.312 ± 2.372
1.328ArgTrp: 1.328 ± 1.356
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
6.64SerAla: 6.64 ± 2.904
1.328SerCys: 1.328 ± 1.272
5.312SerAsp: 5.312 ± 3.568
1.328SerGlu: 1.328 ± 1.214
0.0SerPhe: 0.0 ± 0.0
3.984SerGly: 3.984 ± 2.352
3.984SerHis: 3.984 ± 2.748
0.0SerIle: 0.0 ± 0.0
1.328SerLys: 1.328 ± 1.679
3.984SerLeu: 3.984 ± 2.786
3.984SerMet: 3.984 ± 1.783
2.656SerAsn: 2.656 ± 2.543
2.656SerPro: 2.656 ± 3.358
1.328SerGln: 1.328 ± 1.272
10.624SerArg: 10.624 ± 4.59
9.296SerSer: 9.296 ± 6.131
2.656SerThr: 2.656 ± 1.863
5.312SerVal: 5.312 ± 2.372
2.656SerTrp: 2.656 ± 1.667
2.656SerTyr: 2.656 ± 1.328
0.0SerXaa: 0.0 ± 0.0
Thr
3.984ThrAla: 3.984 ± 1.665
1.328ThrCys: 1.328 ± 1.272
0.0ThrAsp: 0.0 ± 0.0
1.328ThrGlu: 1.328 ± 1.214
2.656ThrPhe: 2.656 ± 1.741
13.28ThrGly: 13.28 ± 2.308
2.656ThrHis: 2.656 ± 1.253
3.984ThrIle: 3.984 ± 2.742
1.328ThrLys: 1.328 ± 1.272
6.64ThrLeu: 6.64 ± 3.543
2.656ThrMet: 2.656 ± 1.211
2.656ThrAsn: 2.656 ± 1.211
2.656ThrPro: 2.656 ± 1.863
2.656ThrGln: 2.656 ± 1.863
6.64ThrArg: 6.64 ± 3.343
2.656ThrSer: 2.656 ± 3.358
2.656ThrThr: 2.656 ± 1.211
1.328ThrVal: 1.328 ± 0.916
0.0ThrTrp: 0.0 ± 0.0
2.656ThrTyr: 2.656 ± 1.832
0.0ThrXaa: 0.0 ± 0.0
Val
1.328ValAla: 1.328 ± 0.916
3.984ValCys: 3.984 ± 1.789
1.328ValAsp: 1.328 ± 1.356
0.0ValGlu: 0.0 ± 0.0
1.328ValPhe: 1.328 ± 0.916
2.656ValGly: 2.656 ± 1.211
1.328ValHis: 1.328 ± 1.356
2.656ValIle: 2.656 ± 2.713
3.984ValLys: 3.984 ± 1.363
1.328ValLeu: 1.328 ± 0.916
0.0ValMet: 0.0 ± 0.0
3.984ValAsn: 3.984 ± 3.462
5.312ValPro: 5.312 ± 3.665
2.656ValGln: 2.656 ± 1.832
6.64ValArg: 6.64 ± 2.247
6.64ValSer: 6.64 ± 3.707
3.984ValThr: 3.984 ± 1.665
0.0ValVal: 0.0 ± 0.0
2.656ValTrp: 2.656 ± 1.253
2.656ValTyr: 2.656 ± 1.211
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.328TrpCys: 1.328 ± 1.272
1.328TrpAsp: 1.328 ± 1.214
1.328TrpGlu: 1.328 ± 1.214
0.0TrpPhe: 0.0 ± 0.0
1.328TrpGly: 1.328 ± 1.214
0.0TrpHis: 0.0 ± 0.0
1.328TrpIle: 1.328 ± 1.356
1.328TrpLys: 1.328 ± 1.272
1.328TrpLeu: 1.328 ± 0.916
1.328TrpMet: 1.328 ± 0.916
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.656TrpArg: 2.656 ± 1.667
0.0TrpSer: 0.0 ± 0.0
1.328TrpThr: 1.328 ± 1.356
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.328TrpTyr: 1.328 ± 1.272
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
3.984TyrAsp: 3.984 ± 1.932
5.312TyrGlu: 5.312 ± 1.742
2.656TyrPhe: 2.656 ± 1.253
2.656TyrGly: 2.656 ± 1.328
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
2.656TyrLeu: 2.656 ± 1.667
1.328TyrMet: 1.328 ± 1.122
2.656TyrAsn: 2.656 ± 1.832
0.0TyrPro: 0.0 ± 0.0
2.656TyrGln: 2.656 ± 1.253
2.656TyrArg: 2.656 ± 1.667
2.656TyrSer: 2.656 ± 1.832
1.328TyrThr: 1.328 ± 0.916
3.984TyrVal: 3.984 ± 2.403
1.328TyrTrp: 1.328 ± 0.916
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (754 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski