Amino acid dipepetide frequency for Trichosporon asahii var. asahii (strain CBS 8904) (Yeast)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.55AlaAla: 12.55 ± 0.089	1.004AlaCys: 1.004 ± 0.015	5.063AlaAsp: 5.063 ± 0.036	6.444AlaGlu: 6.444 ± 0.057	3.047AlaPhe: 3.047 ± 0.033	7.021AlaGly: 7.021 ± 0.049	2.162AlaHis: 2.162 ± 0.024	3.825AlaIle: 3.825 ± 0.033	4.583AlaLys: 4.583 ± 0.045	8.765AlaLeu: 8.765 ± 0.063	2.118AlaMet: 2.118 ± 0.024	2.974AlaAsn: 2.974 ± 0.028	7.214AlaPro: 7.214 ± 0.07	4.096AlaGln: 4.096 ± 0.043	6.222AlaArg: 6.222 ± 0.05	8.451AlaSer: 8.451 ± 0.077	5.67AlaThr: 5.67 ± 0.036	6.095AlaVal: 6.095 ± 0.049	1.285AlaTrp: 1.285 ± 0.017	2.178AlaTyr: 2.178 ± 0.027	0.0AlaXaa: 0.0 ± 0.0
Cys	1.001CysAla: 1.001 ± 0.017	0.218CysCys: 0.218 ± 0.009	0.62CysAsp: 0.62 ± 0.015	0.576CysGlu: 0.576 ± 0.012	0.418CysPhe: 0.418 ± 0.011	0.85CysGly: 0.85 ± 0.018	0.255CysHis: 0.255 ± 0.008	0.52CysIle: 0.52 ± 0.011	0.456CysLys: 0.456 ± 0.012	1.03CysLeu: 1.03 ± 0.018	0.238CysMet: 0.238 ± 0.008	0.332CysAsn: 0.332 ± 0.01	0.669CysPro: 0.669 ± 0.015	0.363CysGln: 0.363 ± 0.01	0.687CysArg: 0.687 ± 0.013	0.809CysSer: 0.809 ± 0.016	0.614CysThr: 0.614 ± 0.012	0.755CysVal: 0.755 ± 0.014	0.179CysTrp: 0.179 ± 0.007	0.294CysTyr: 0.294 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.525AspAla: 5.525 ± 0.04	0.57AspCys: 0.57 ± 0.013	4.615AspAsp: 4.615 ± 0.051	4.877AspGlu: 4.877 ± 0.049	1.867AspPhe: 1.867 ± 0.025	4.31AspGly: 4.31 ± 0.042	1.219AspHis: 1.219 ± 0.019	2.395AspIle: 2.395 ± 0.026	2.513AspLys: 2.513 ± 0.029	4.898AspLeu: 4.898 ± 0.039	1.278AspMet: 1.278 ± 0.016	1.647AspAsn: 1.647 ± 0.024	3.599AspPro: 3.599 ± 0.033	1.721AspGln: 1.721 ± 0.024	3.269AspArg: 3.269 ± 0.043	4.027AspSer: 4.027 ± 0.039	2.806AspThr: 2.806 ± 0.028	3.939AspVal: 3.939 ± 0.033	0.949AspTrp: 0.949 ± 0.016	1.415AspTyr: 1.415 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	6.194GluAla: 6.194 ± 0.049	0.618GluCys: 0.618 ± 0.013	4.285GluAsp: 4.285 ± 0.048	5.816GluGlu: 5.816 ± 0.067	1.688GluPhe: 1.688 ± 0.019	4.269GluGly: 4.269 ± 0.037	1.436GluHis: 1.436 ± 0.021	2.507GluIle: 2.507 ± 0.026	3.405GluLys: 3.405 ± 0.037	5.397GluLeu: 5.397 ± 0.044	1.342GluMet: 1.342 ± 0.018	1.732GluAsn: 1.732 ± 0.022	3.488GluPro: 3.488 ± 0.046	2.451GluGln: 2.451 ± 0.026	4.779GluArg: 4.779 ± 0.052	3.902GluSer: 3.902 ± 0.039	3.147GluThr: 3.147 ± 0.03	3.752GluVal: 3.752 ± 0.033	0.973GluTrp: 0.973 ± 0.015	1.526GluTyr: 1.526 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	2.963PheAla: 2.963 ± 0.034	0.446PheCys: 0.446 ± 0.012	2.074PheAsp: 2.074 ± 0.023	1.845PheGlu: 1.845 ± 0.022	1.234PhePhe: 1.234 ± 0.021	2.669PheGly: 2.669 ± 0.044	0.739PheHis: 0.739 ± 0.014	1.335PheIle: 1.335 ± 0.023	1.318PheLys: 1.318 ± 0.02	2.78PheLeu: 2.78 ± 0.028	0.653PheMet: 0.653 ± 0.013	1.167PheAsn: 1.167 ± 0.016	1.826PhePro: 1.826 ± 0.022	1.042PheGln: 1.042 ± 0.016	1.74PheArg: 1.74 ± 0.019	2.427PheSer: 2.427 ± 0.026	1.79PheThr: 1.79 ± 0.024	2.126PheVal: 2.126 ± 0.025	0.522PheTrp: 0.522 ± 0.012	0.84PheTyr: 0.84 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	6.518GlyAla: 6.518 ± 0.054	0.825GlyCys: 0.825 ± 0.02	3.918GlyAsp: 3.918 ± 0.037	4.228GlyGlu: 4.228 ± 0.038	2.412GlyPhe: 2.412 ± 0.033	6.96GlyGly: 6.96 ± 0.09	1.851GlyHis: 1.851 ± 0.028	2.902GlyIle: 2.902 ± 0.032	3.639GlyLys: 3.639 ± 0.039	5.913GlyLeu: 5.913 ± 0.05	1.648GlyMet: 1.648 ± 0.027	2.29GlyAsn: 2.29 ± 0.03	4.006GlyPro: 4.006 ± 0.035	2.89GlyGln: 2.89 ± 0.066	4.576GlyArg: 4.576 ± 0.042	6.171GlySer: 6.171 ± 0.062	4.09GlyThr: 4.09 ± 0.05	4.653GlyVal: 4.653 ± 0.038	1.281GlyTrp: 1.281 ± 0.022	1.93GlyTyr: 1.93 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	2.177HisAla: 2.177 ± 0.026	0.295HisCys: 0.295 ± 0.009	1.317HisAsp: 1.317 ± 0.017	1.238HisGlu: 1.238 ± 0.018	0.764HisPhe: 0.764 ± 0.015	1.77HisGly: 1.77 ± 0.023	0.896HisHis: 0.896 ± 0.021	0.995HisIle: 0.995 ± 0.016	0.805HisLys: 0.805 ± 0.015	2.25HisLeu: 2.25 ± 0.024	0.457HisMet: 0.457 ± 0.012	0.694HisAsn: 0.694 ± 0.011	1.889HisPro: 1.889 ± 0.023	0.906HisGln: 0.906 ± 0.018	1.545HisArg: 1.545 ± 0.019	1.898HisSer: 1.898 ± 0.027	1.257HisThr: 1.257 ± 0.017	1.493HisVal: 1.493 ± 0.023	0.344HisTrp: 0.344 ± 0.011	0.589HisTyr: 0.589 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.911IleAla: 3.911 ± 0.031	0.522IleCys: 0.522 ± 0.013	2.598IleAsp: 2.598 ± 0.026	2.459IleGlu: 2.459 ± 0.03	1.335IlePhe: 1.335 ± 0.019	2.737IleGly: 2.737 ± 0.031	0.855IleHis: 0.855 ± 0.016	1.726IleIle: 1.726 ± 0.026	1.838IleLys: 1.838 ± 0.024	3.385IleLeu: 3.385 ± 0.035	0.811IleMet: 0.811 ± 0.015	1.369IleAsn: 1.369 ± 0.02	2.694IlePro: 2.694 ± 0.027	1.332IleGln: 1.332 ± 0.019	2.348IleArg: 2.348 ± 0.022	2.822IleSer: 2.822 ± 0.03	2.218IleThr: 2.218 ± 0.025	2.82IleVal: 2.82 ± 0.031	0.533IleTrp: 0.533 ± 0.011	0.961IleTyr: 0.961 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.668LysAla: 4.668 ± 0.046	0.423LysCys: 0.423 ± 0.012	2.7LysAsp: 2.7 ± 0.033	3.331LysGlu: 3.331 ± 0.038	1.179LysPhe: 1.179 ± 0.017	3.087LysGly: 3.087 ± 0.035	1.012LysHis: 1.012 ± 0.014	1.746LysIle: 1.746 ± 0.023	3.138LysLys: 3.138 ± 0.05	3.798LysLeu: 3.798 ± 0.034	0.924LysMet: 0.924 ± 0.017	1.412LysAsn: 1.412 ± 0.023	3.017LysPro: 3.017 ± 0.031	1.702LysGln: 1.702 ± 0.023	3.566LysArg: 3.566 ± 0.034	2.979LysSer: 2.979 ± 0.029	2.462LysThr: 2.462 ± 0.026	2.719LysVal: 2.719 ± 0.031	0.636LysTrp: 0.636 ± 0.014	1.101LysTyr: 1.101 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	8.722LeuAla: 8.722 ± 0.05	1.093LeuCys: 1.093 ± 0.015	5.107LeuAsp: 5.107 ± 0.04	5.155LeuGlu: 5.155 ± 0.046	2.844LeuPhe: 2.844 ± 0.032	6.112LeuGly: 6.112 ± 0.048	2.105LeuHis: 2.105 ± 0.024	3.237LeuIle: 3.237 ± 0.036	3.769LeuLys: 3.769 ± 0.036	7.846LeuLeu: 7.846 ± 0.066	1.642LeuMet: 1.642 ± 0.022	2.765LeuAsn: 2.765 ± 0.028	6.289LeuPro: 6.289 ± 0.044	3.297LeuGln: 3.297 ± 0.031	5.953LeuArg: 5.953 ± 0.05	7.039LeuSer: 7.039 ± 0.057	4.72LeuThr: 4.72 ± 0.036	5.318LeuVal: 5.318 ± 0.051	1.111LeuTrp: 1.111 ± 0.019	1.947LeuTyr: 1.947 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.061MetAla: 2.061 ± 0.025	0.237MetCys: 0.237 ± 0.008	1.186MetAsp: 1.186 ± 0.016	1.106MetGlu: 1.106 ± 0.018	0.692MetPhe: 0.692 ± 0.013	1.498MetGly: 1.498 ± 0.023	0.403MetHis: 0.403 ± 0.011	0.774MetIle: 0.774 ± 0.015	0.818MetLys: 0.818 ± 0.016	1.775MetLeu: 1.775 ± 0.022	0.515MetMet: 0.515 ± 0.014	0.669MetAsn: 0.669 ± 0.014	1.444MetPro: 1.444 ± 0.021	0.726MetGln: 0.726 ± 0.016	1.372MetArg: 1.372 ± 0.02	1.995MetSer: 1.995 ± 0.024	1.268MetThr: 1.268 ± 0.02	1.176MetVal: 1.176 ± 0.018	0.257MetTrp: 0.257 ± 0.008	0.457MetTyr: 0.457 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.15AsnAla: 3.15 ± 0.029	0.324AsnCys: 0.324 ± 0.01	1.692AsnAsp: 1.692 ± 0.018	1.705AsnGlu: 1.705 ± 0.02	0.988AsnPhe: 0.988 ± 0.019	2.858AsnGly: 2.858 ± 0.036	0.671AsnHis: 0.671 ± 0.015	1.381AsnIle: 1.381 ± 0.02	1.344AsnLys: 1.344 ± 0.02	2.695AsnLeu: 2.695 ± 0.03	0.713AsnMet: 0.713 ± 0.014	1.147AsnAsn: 1.147 ± 0.024	2.226AsnPro: 2.226 ± 0.024	1.092AsnGln: 1.092 ± 0.02	1.732AsnArg: 1.732 ± 0.023	2.239AsnSer: 2.239 ± 0.024	1.705AsnThr: 1.705 ± 0.021	2.173AsnVal: 2.173 ± 0.023	0.461AsnTrp: 0.461 ± 0.013	0.804AsnTyr: 0.804 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	7.632ProAla: 7.632 ± 0.077	0.527ProCys: 0.527 ± 0.011	3.465ProAsp: 3.465 ± 0.029	4.419ProGlu: 4.419 ± 0.038	1.963ProPhe: 1.963 ± 0.026	4.762ProGly: 4.762 ± 0.044	1.617ProHis: 1.617 ± 0.024	2.42ProIle: 2.42 ± 0.025	3.033ProLys: 3.033 ± 0.034	5.51ProLeu: 5.51 ± 0.043	1.206ProMet: 1.206 ± 0.019	2.126ProAsn: 2.126 ± 0.026	7.793ProPro: 7.793 ± 0.119	2.791ProGln: 2.791 ± 0.034	4.464ProArg: 4.464 ± 0.053	7.658ProSer: 7.658 ± 0.095	4.921ProThr: 4.921 ± 0.049	4.384ProVal: 4.384 ± 0.04	0.759ProTrp: 0.759 ± 0.015	1.474ProTyr: 1.474 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.965GlnAla: 3.965 ± 0.04	0.403GlnCys: 0.403 ± 0.011	1.69GlnAsp: 1.69 ± 0.023	2.021GlnGlu: 2.021 ± 0.021	1.11GlnPhe: 1.11 ± 0.017	2.422GlnGly: 2.422 ± 0.068	1.086GlnHis: 1.086 ± 0.017	1.423GlnIle: 1.423 ± 0.016	1.572GlnLys: 1.572 ± 0.025	3.429GlnLeu: 3.429 ± 0.036	0.834GlnMet: 0.834 ± 0.015	1.194GlnAsn: 1.194 ± 0.02	3.031GlnPro: 3.031 ± 0.04	2.781GlnGln: 2.781 ± 0.075	2.799GlnArg: 2.799 ± 0.031	2.832GlnSer: 2.832 ± 0.033	2.072GlnThr: 2.072 ± 0.022	2.241GlnVal: 2.241 ± 0.054	0.565GlnTrp: 0.565 ± 0.013	0.987GlnTyr: 0.987 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	6.33ArgAla: 6.33 ± 0.051	0.68ArgCys: 0.68 ± 0.013	3.71ArgAsp: 3.71 ± 0.047	4.168ArgGlu: 4.168 ± 0.049	1.969ArgPhe: 1.969 ± 0.022	4.245ArgGly: 4.245 ± 0.04	1.651ArgHis: 1.651 ± 0.02	2.546ArgIle: 2.546 ± 0.025	3.317ArgLys: 3.317 ± 0.033	5.733ArgLeu: 5.733 ± 0.048	1.319ArgMet: 1.319 ± 0.016	1.978ArgAsn: 1.978 ± 0.022	4.51ArgPro: 4.51 ± 0.044	2.629ArgGln: 2.629 ± 0.03	6.122ArgArg: 6.122 ± 0.054	5.281ArgSer: 5.281 ± 0.061	3.517ArgThr: 3.517 ± 0.032	3.822ArgVal: 3.822 ± 0.029	0.962ArgTrp: 0.962 ± 0.018	1.534ArgTyr: 1.534 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	8.336SerAla: 8.336 ± 0.084	0.744SerCys: 0.744 ± 0.015	4.335SerAsp: 4.335 ± 0.042	4.086SerGlu: 4.086 ± 0.034	2.552SerPhe: 2.552 ± 0.032	6.004SerGly: 6.004 ± 0.05	1.883SerHis: 1.883 ± 0.027	2.923SerIle: 2.923 ± 0.026	3.283SerLys: 3.283 ± 0.035	6.735SerLeu: 6.735 ± 0.054	1.577SerMet: 1.577 ± 0.022	2.454SerAsn: 2.454 ± 0.031	6.89SerPro: 6.89 ± 0.076	2.888SerGln: 2.888 ± 0.032	5.142SerArg: 5.142 ± 0.044	9.268SerSer: 9.268 ± 0.105	5.728SerThr: 5.728 ± 0.081	4.764SerVal: 4.764 ± 0.036	0.985SerTrp: 0.985 ± 0.016	1.738SerTyr: 1.738 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.691ThrAla: 5.691 ± 0.041	0.624ThrCys: 0.624 ± 0.014	2.728ThrAsp: 2.728 ± 0.03	3.021ThrGlu: 3.021 ± 0.029	1.929ThrPhe: 1.929 ± 0.021	4.133ThrGly: 4.133 ± 0.057	1.295ThrHis: 1.295 ± 0.021	2.381ThrIle: 2.381 ± 0.022	2.249ThrLys: 2.249 ± 0.026	5.07ThrLeu: 5.07 ± 0.038	1.08ThrMet: 1.08 ± 0.017	1.67ThrAsn: 1.67 ± 0.022	5.756ThrPro: 5.756 ± 0.057	2.018ThrGln: 2.018 ± 0.054	3.242ThrArg: 3.242 ± 0.027	5.16ThrSer: 5.16 ± 0.044	3.933ThrThr: 3.933 ± 0.045	3.627ThrVal: 3.627 ± 0.031	0.759ThrTrp: 0.759 ± 0.016	1.34ThrTyr: 1.34 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.875ValAla: 5.875 ± 0.042	0.81ValCys: 0.81 ± 0.015	3.781ValAsp: 3.781 ± 0.034	3.939ValGlu: 3.939 ± 0.045	2.179ValPhe: 2.179 ± 0.03	4.137ValGly: 4.137 ± 0.038	1.476ValHis: 1.476 ± 0.018	2.616ValIle: 2.616 ± 0.025	2.883ValLys: 2.883 ± 0.033	5.666ValLeu: 5.666 ± 0.049	1.266ValMet: 1.266 ± 0.019	2.055ValAsn: 2.055 ± 0.023	4.495ValPro: 4.495 ± 0.06	2.385ValGln: 2.385 ± 0.028	3.958ValArg: 3.958 ± 0.032	4.684ValSer: 4.684 ± 0.04	3.59ValThr: 3.59 ± 0.03	4.445ValVal: 4.445 ± 0.064	0.887ValTrp: 0.887 ± 0.015	1.515ValTyr: 1.515 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.27TrpAla: 1.27 ± 0.019	0.191TrpCys: 0.191 ± 0.007	0.95TrpAsp: 0.95 ± 0.016	0.879TrpGlu: 0.879 ± 0.016	0.483TrpPhe: 0.483 ± 0.012	0.992TrpGly: 0.992 ± 0.02	0.333TrpHis: 0.333 ± 0.009	0.625TrpIle: 0.625 ± 0.013	0.705TrpLys: 0.705 ± 0.015	1.214TrpLeu: 1.214 ± 0.016	0.322TrpMet: 0.322 ± 0.01	0.548TrpAsn: 0.548 ± 0.012	0.668TrpPro: 0.668 ± 0.014	0.503TrpGln: 0.503 ± 0.011	1.028TrpArg: 1.028 ± 0.017	1.038TrpSer: 1.038 ± 0.016	0.86TrpThr: 0.86 ± 0.014	0.859TrpVal: 0.859 ± 0.015	0.3TrpTrp: 0.3 ± 0.011	0.354TrpTyr: 0.354 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.229TyrAla: 2.229 ± 0.023	0.333TyrCys: 0.333 ± 0.008	1.604TyrAsp: 1.604 ± 0.024	1.392TyrGlu: 1.392 ± 0.022	0.882TyrPhe: 0.882 ± 0.019	1.865TyrGly: 1.865 ± 0.026	0.636TyrHis: 0.636 ± 0.013	0.999TyrIle: 0.999 ± 0.018	0.933TyrLys: 0.933 ± 0.015	2.183TyrLeu: 2.183 ± 0.026	0.487TyrMet: 0.487 ± 0.011	0.877TyrAsn: 0.877 ± 0.014	1.418TyrPro: 1.418 ± 0.022	0.845TyrGln: 0.845 ± 0.014	1.478TyrArg: 1.478 ± 0.02	1.636TyrSer: 1.636 ± 0.021	1.336TyrThr: 1.336 ± 0.021	1.48TyrVal: 1.48 ± 0.019	0.371TyrTrp: 0.371 ± 0.01	0.73TyrTyr: 0.73 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8515 proteins (4190985 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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