Amino acid dipepetide frequency for Bat polyomavirus 6c

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.185AlaAla: 7.185 ± 2.091
0.653AlaCys: 0.653 ± 0.415
3.919AlaAsp: 3.919 ± 1.672
4.572AlaGlu: 4.572 ± 2.811
3.266AlaPhe: 3.266 ± 1.877
2.613AlaGly: 2.613 ± 0.892
1.306AlaHis: 1.306 ± 0.724
3.919AlaIle: 3.919 ± 1.761
2.613AlaLys: 2.613 ± 0.751
8.491AlaLeu: 8.491 ± 4.909
0.653AlaMet: 0.653 ± 0.653
2.613AlaAsn: 2.613 ± 1.163
1.96AlaPro: 1.96 ± 1.094
3.266AlaGln: 3.266 ± 1.104
2.613AlaArg: 2.613 ± 1.164
2.613AlaSer: 2.613 ± 0.892
1.306AlaThr: 1.306 ± 1.193
6.532AlaVal: 6.532 ± 2.921
1.306AlaTrp: 1.306 ± 0.829
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.653CysAla: 0.653 ± 0.653
0.0CysCys: 0.0 ± 0.0
1.306CysAsp: 1.306 ± 0.829
0.0CysGlu: 0.0 ± 0.0
0.653CysPhe: 0.653 ± 0.814
1.306CysGly: 1.306 ± 0.508
1.306CysHis: 1.306 ± 0.736
1.306CysIle: 1.306 ± 0.829
2.613CysLys: 2.613 ± 0.751
2.613CysLeu: 2.613 ± 1.473
0.653CysMet: 0.653 ± 0.814
0.653CysAsn: 0.653 ± 0.814
0.653CysPro: 0.653 ± 0.653
1.306CysGln: 1.306 ± 0.508
1.306CysArg: 1.306 ± 0.829
3.266CysSer: 3.266 ± 2.073
0.653CysThr: 0.653 ± 0.415
1.306CysVal: 1.306 ± 0.508
0.0CysTrp: 0.0 ± 0.0
1.306CysTyr: 1.306 ± 1.627
0.0CysXaa: 0.0 ± 0.0
Asp
1.96AspAla: 1.96 ± 1.243
1.306AspCys: 1.306 ± 0.829
3.266AspAsp: 3.266 ± 1.009
2.613AspGlu: 2.613 ± 1.473
3.266AspPhe: 3.266 ± 1.347
1.306AspGly: 1.306 ± 0.587
1.96AspHis: 1.96 ± 0.875
2.613AspIle: 2.613 ± 0.923
3.919AspLys: 3.919 ± 0.465
5.879AspLeu: 5.879 ± 1.895
2.613AspMet: 2.613 ± 1.294
5.225AspAsn: 5.225 ± 1.739
3.266AspPro: 3.266 ± 1.926
1.306AspGln: 1.306 ± 0.508
1.306AspArg: 1.306 ± 0.829
2.613AspSer: 2.613 ± 1.015
1.306AspThr: 1.306 ± 0.736
1.96AspVal: 1.96 ± 0.658
1.96AspTrp: 1.96 ± 1.057
1.306AspTyr: 1.306 ± 0.587
0.0AspXaa: 0.0 ± 0.0
Glu
4.572GluAla: 4.572 ± 1.257
1.96GluCys: 1.96 ± 1.496
4.572GluAsp: 4.572 ± 0.777
14.37GluGlu: 14.37 ± 4.325
4.572GluPhe: 4.572 ± 2.334
1.96GluGly: 1.96 ± 1.154
2.613GluHis: 2.613 ± 0.751
1.306GluIle: 1.306 ± 1.307
2.613GluLys: 2.613 ± 1.659
7.838GluLeu: 7.838 ± 2.223
0.653GluMet: 0.653 ± 0.415
3.919GluAsn: 3.919 ± 1.579
3.266GluPro: 3.266 ± 1.099
1.96GluGln: 1.96 ± 0.875
0.653GluArg: 0.653 ± 0.814
6.532GluSer: 6.532 ± 1.605
5.879GluThr: 5.879 ± 2.021
7.185GluVal: 7.185 ± 2.479
0.653GluTrp: 0.653 ± 0.415
0.653GluTyr: 0.653 ± 0.415
0.0GluXaa: 0.0 ± 0.0
Phe
3.919PheAla: 3.919 ± 1.738
3.266PheCys: 3.266 ± 0.89
2.613PheAsp: 2.613 ± 1.659
3.266PheGlu: 3.266 ± 1.541
0.653PhePhe: 0.653 ± 0.415
2.613PheGly: 2.613 ± 1.559
3.266PheHis: 3.266 ± 1.103
1.306PheIle: 1.306 ± 0.829
1.306PheLys: 1.306 ± 0.736
9.144PheLeu: 9.144 ± 2.13
0.653PheMet: 0.653 ± 0.415
2.613PheAsn: 2.613 ± 0.923
3.266PhePro: 3.266 ± 0.415
1.96PheGln: 1.96 ± 0.823
1.96PheArg: 1.96 ± 1.108
0.653PheSer: 0.653 ± 0.596
5.225PheThr: 5.225 ± 1.468
2.613PheVal: 2.613 ± 1.164
1.306PheTrp: 1.306 ± 0.587
0.653PheTyr: 0.653 ± 0.653
0.0PheXaa: 0.0 ± 0.0
Gly
3.266GlyAla: 3.266 ± 1.671
0.0GlyCys: 0.0 ± 0.0
4.572GlyAsp: 4.572 ± 1.346
2.613GlyGlu: 2.613 ± 1.447
1.96GlyPhe: 1.96 ± 0.769
5.879GlyGly: 5.879 ± 0.89
0.653GlyHis: 0.653 ± 0.415
4.572GlyIle: 4.572 ± 0.777
1.96GlyLys: 1.96 ± 0.658
7.185GlyLeu: 7.185 ± 1.471
0.653GlyMet: 0.653 ± 0.653
1.306GlyAsn: 1.306 ± 0.736
2.613GlyPro: 2.613 ± 0.923
3.266GlyGln: 3.266 ± 0.778
1.306GlyArg: 1.306 ± 1.193
0.653GlySer: 0.653 ± 0.653
3.919GlyThr: 3.919 ± 1.672
3.266GlyVal: 3.266 ± 0.709
0.0GlyTrp: 0.0 ± 0.0
1.306GlyTyr: 1.306 ± 0.508
0.0GlyXaa: 0.0 ± 0.0
His
1.306HisAla: 1.306 ± 0.736
0.653HisCys: 0.653 ± 0.415
0.0HisAsp: 0.0 ± 0.0
0.653HisGlu: 0.653 ± 0.653
0.653HisPhe: 0.653 ± 0.415
0.653HisGly: 0.653 ± 0.415
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.613HisLys: 2.613 ± 1.659
3.266HisLeu: 3.266 ± 1.499
1.306HisMet: 1.306 ± 0.681
1.306HisAsn: 1.306 ± 1.627
1.306HisPro: 1.306 ± 0.736
1.306HisGln: 1.306 ± 0.508
1.306HisArg: 1.306 ± 0.587
1.306HisSer: 1.306 ± 1.069
0.0HisThr: 0.0 ± 0.0
1.306HisVal: 1.306 ± 0.736
0.653HisTrp: 0.653 ± 0.596
0.653HisTyr: 0.653 ± 0.596
0.0HisXaa: 0.0 ± 0.0
Ile
3.266IleAla: 3.266 ± 1.681
1.96IleCys: 1.96 ± 0.658
2.613IleAsp: 2.613 ± 0.404
3.266IleGlu: 3.266 ± 1.576
1.96IlePhe: 1.96 ± 0.875
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
2.613IleIle: 2.613 ± 1.473
2.613IleLys: 2.613 ± 1.155
5.225IleLeu: 5.225 ± 0.381
0.0IleMet: 0.0 ± 0.0
2.613IleAsn: 2.613 ± 1.659
1.96IlePro: 1.96 ± 0.658
0.0IleGln: 0.0 ± 0.0
0.653IleArg: 0.653 ± 0.415
6.532IleSer: 6.532 ± 1.612
3.919IleThr: 3.919 ± 1.302
3.266IleVal: 3.266 ± 1.545
0.0IleTrp: 0.0 ± 0.0
0.653IleTyr: 0.653 ± 0.653
0.0IleXaa: 0.0 ± 0.0
Lys
2.613LysAla: 2.613 ± 1.559
1.96LysCys: 1.96 ± 1.496
1.96LysAsp: 1.96 ± 1.244
3.919LysGlu: 3.919 ± 1.167
0.0LysPhe: 0.0 ± 0.0
6.532LysGly: 6.532 ± 1.754
1.306LysHis: 1.306 ± 0.829
2.613LysIle: 2.613 ± 0.923
10.451LysLys: 10.451 ± 2.43
5.225LysLeu: 5.225 ± 1.739
1.96LysMet: 1.96 ± 0.658
3.266LysAsn: 3.266 ± 1.103
1.306LysPro: 1.306 ± 0.829
1.96LysGln: 1.96 ± 0.414
7.185LysArg: 7.185 ± 1.222
2.613LysSer: 2.613 ± 1.659
5.879LysThr: 5.879 ± 1.073
1.96LysVal: 1.96 ± 0.823
0.0LysTrp: 0.0 ± 0.0
3.266LysTyr: 3.266 ± 0.89
0.0LysXaa: 0.0 ± 0.0
Leu
3.919LeuAla: 3.919 ± 2.855
1.96LeuCys: 1.96 ± 0.658
5.225LeuAsp: 5.225 ± 0.561
7.838LeuGlu: 7.838 ± 2.378
7.838LeuPhe: 7.838 ± 1.435
3.266LeuGly: 3.266 ± 1.46
0.653LeuHis: 0.653 ± 0.814
3.919LeuIle: 3.919 ± 0.701
3.919LeuLys: 3.919 ± 1.315
12.41LeuLeu: 12.41 ± 2.909
4.572LeuMet: 4.572 ± 1.914
10.451LeuAsn: 10.451 ± 1.199
7.185LeuPro: 7.185 ± 0.679
3.266LeuGln: 3.266 ± 0.778
5.225LeuArg: 5.225 ± 1.168
9.144LeuSer: 9.144 ± 1.743
5.879LeuThr: 5.879 ± 1.68
1.96LeuVal: 1.96 ± 0.414
1.306LeuTrp: 1.306 ± 0.736
6.532LeuTyr: 6.532 ± 2.201
0.0LeuXaa: 0.0 ± 0.0
Met
3.919MetAla: 3.919 ± 0.752
0.0MetCys: 0.0 ± 0.0
1.306MetAsp: 1.306 ± 0.736
3.919MetGlu: 3.919 ± 1.751
1.96MetPhe: 1.96 ± 0.826
2.613MetGly: 2.613 ± 0.687
0.653MetHis: 0.653 ± 0.596
2.613MetIle: 2.613 ± 0.975
2.613MetLys: 2.613 ± 1.294
3.266MetLeu: 3.266 ± 2.03
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.96MetPro: 1.96 ± 0.823
1.306MetGln: 1.306 ± 1.307
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
1.306MetVal: 1.306 ± 0.508
0.653MetTrp: 0.653 ± 0.653
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.225AsnAla: 5.225 ± 2.2
1.306AsnCys: 1.306 ± 0.829
0.653AsnAsp: 0.653 ± 0.415
3.919AsnGlu: 3.919 ± 1.65
3.266AsnPhe: 3.266 ± 1.009
1.306AsnGly: 1.306 ± 0.724
0.653AsnHis: 0.653 ± 0.415
2.613AsnIle: 2.613 ± 0.975
1.96AsnLys: 1.96 ± 1.244
5.879AsnLeu: 5.879 ± 1.339
3.919AsnMet: 3.919 ± 0.694
3.266AsnAsn: 3.266 ± 2.073
4.572AsnPro: 4.572 ± 1.935
1.96AsnGln: 1.96 ± 1.108
0.653AsnArg: 0.653 ± 0.415
1.306AsnSer: 1.306 ± 1.307
3.266AsnThr: 3.266 ± 1.103
3.919AsnVal: 3.919 ± 0.701
0.0AsnTrp: 0.0 ± 0.0
2.613AsnTyr: 2.613 ± 0.892
0.0AsnXaa: 0.0 ± 0.0
Pro
0.653ProAla: 0.653 ± 0.653
0.653ProCys: 0.653 ± 0.814
6.532ProAsp: 6.532 ± 1.514
2.613ProGlu: 2.613 ± 1.659
3.266ProPhe: 3.266 ± 0.778
5.225ProGly: 5.225 ± 0.808
0.653ProHis: 0.653 ± 0.596
1.96ProIle: 1.96 ± 1.243
3.919ProLys: 3.919 ± 1.302
4.572ProLeu: 4.572 ± 2.15
3.266ProMet: 3.266 ± 1.099
1.306ProAsn: 1.306 ± 0.587
6.532ProPro: 6.532 ± 1.224
0.653ProGln: 0.653 ± 0.596
2.613ProArg: 2.613 ± 2.614
3.266ProSer: 3.266 ± 1.104
3.266ProThr: 3.266 ± 1.541
2.613ProVal: 2.613 ± 1.729
0.0ProTrp: 0.0 ± 0.0
3.266ProTyr: 3.266 ± 0.415
0.0ProXaa: 0.0 ± 0.0
Gln
1.96GlnAla: 1.96 ± 0.658
0.0GlnCys: 0.0 ± 0.0
1.306GlnAsp: 1.306 ± 0.829
1.306GlnGlu: 1.306 ± 0.508
4.572GlnPhe: 4.572 ± 1.154
1.96GlnGly: 1.96 ± 0.414
0.0GlnHis: 0.0 ± 0.0
1.306GlnIle: 1.306 ± 0.508
3.919GlnLys: 3.919 ± 1.871
4.572GlnLeu: 4.572 ± 0.705
0.653GlnMet: 0.653 ± 0.596
2.613GlnAsn: 2.613 ± 0.923
1.96GlnPro: 1.96 ± 1.154
2.613GlnGln: 2.613 ± 0.892
3.919GlnArg: 3.919 ± 2.238
2.613GlnSer: 2.613 ± 1.659
0.653GlnThr: 0.653 ± 0.596
2.613GlnVal: 2.613 ± 1.447
0.0GlnTrp: 0.0 ± 0.0
1.306GlnTyr: 1.306 ± 0.724
0.0GlnXaa: 0.0 ± 0.0
Arg
3.266ArgAla: 3.266 ± 1.101
0.653ArgCys: 0.653 ± 0.814
2.613ArgAsp: 2.613 ± 0.751
5.879ArgGlu: 5.879 ± 1.052
2.613ArgPhe: 2.613 ± 1.164
0.653ArgGly: 0.653 ± 0.653
2.613ArgHis: 2.613 ± 0.796
1.96ArgIle: 1.96 ± 1.094
2.613ArgLys: 2.613 ± 1.559
2.613ArgLeu: 2.613 ± 0.796
0.653ArgMet: 0.653 ± 0.653
1.306ArgAsn: 1.306 ± 0.829
1.96ArgPro: 1.96 ± 1.243
1.306ArgGln: 1.306 ± 1.193
1.96ArgArg: 1.96 ± 1.108
3.266ArgSer: 3.266 ± 0.706
3.919ArgThr: 3.919 ± 1.579
1.96ArgVal: 1.96 ± 1.244
0.653ArgTrp: 0.653 ± 0.596
2.613ArgTyr: 2.613 ± 1.85
0.0ArgXaa: 0.0 ± 0.0
Ser
5.225SerAla: 5.225 ± 3.226
0.653SerCys: 0.653 ± 0.415
1.96SerAsp: 1.96 ± 1.96
3.266SerGlu: 3.266 ± 1.541
2.613SerPhe: 2.613 ± 0.751
3.919SerGly: 3.919 ± 1.326
0.0SerHis: 0.0 ± 0.0
2.613SerIle: 2.613 ± 0.796
3.919SerLys: 3.919 ± 0.828
7.838SerLeu: 7.838 ± 1.564
3.266SerMet: 3.266 ± 1.089
2.613SerAsn: 2.613 ± 0.404
1.96SerPro: 1.96 ± 1.108
5.225SerGln: 5.225 ± 2.654
3.266SerArg: 3.266 ± 0.706
7.185SerSer: 7.185 ± 1.288
2.613SerThr: 2.613 ± 0.892
6.532SerVal: 6.532 ± 2.484
3.266SerTrp: 3.266 ± 1.448
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.266ThrAla: 3.266 ± 1.671
3.266ThrCys: 3.266 ± 1.103
2.613ThrAsp: 2.613 ± 0.751
6.532ThrGlu: 6.532 ± 1.516
1.96ThrPhe: 1.96 ± 1.244
3.266ThrGly: 3.266 ± 1.099
0.0ThrHis: 0.0 ± 0.0
1.96ThrIle: 1.96 ± 0.658
3.266ThrLys: 3.266 ± 1.104
4.572ThrLeu: 4.572 ± 1.315
0.0ThrMet: 0.0 ± 0.0
2.613ThrAsn: 2.613 ± 0.923
6.532ThrPro: 6.532 ± 0.561
3.266ThrGln: 3.266 ± 1.099
2.613ThrArg: 2.613 ± 1.155
2.613ThrSer: 2.613 ± 1.163
7.185ThrThr: 7.185 ± 1.214
1.96ThrVal: 1.96 ± 0.658
0.0ThrTrp: 0.0 ± 0.0
1.306ThrTyr: 1.306 ± 1.193
0.0ThrXaa: 0.0 ± 0.0
Val
3.266ValAla: 3.266 ± 1.104
0.653ValCys: 0.653 ± 0.415
2.613ValAsp: 2.613 ± 1.174
4.572ValGlu: 4.572 ± 1.234
3.266ValPhe: 3.266 ± 1.541
3.266ValGly: 3.266 ± 2.48
0.653ValHis: 0.653 ± 0.415
1.96ValIle: 1.96 ± 0.823
3.919ValLys: 3.919 ± 1.523
3.266ValLeu: 3.266 ± 1.576
1.306ValMet: 1.306 ± 0.724
3.266ValAsn: 3.266 ± 0.706
3.919ValPro: 3.919 ± 1.579
2.613ValGln: 2.613 ± 1.294
3.266ValArg: 3.266 ± 1.926
9.144ValSer: 9.144 ± 1.058
2.613ValThr: 2.613 ± 0.923
1.306ValVal: 1.306 ± 0.724
1.306ValTrp: 1.306 ± 0.946
0.653ValTyr: 0.653 ± 0.415
0.0ValXaa: 0.0 ± 0.0
Trp
1.306TrpAla: 1.306 ± 1.193
0.653TrpCys: 0.653 ± 0.653
0.0TrpAsp: 0.0 ± 0.0
1.96TrpGlu: 1.96 ± 0.414
1.306TrpPhe: 1.306 ± 0.736
0.653TrpGly: 0.653 ± 0.814
0.0TrpHis: 0.0 ± 0.0
0.653TrpIle: 0.653 ± 0.814
1.96TrpLys: 1.96 ± 0.875
1.306TrpLeu: 1.306 ± 0.587
0.0TrpMet: 0.0 ± 0.0
0.653TrpAsn: 0.653 ± 0.415
0.0TrpPro: 0.0 ± 0.0
1.306TrpGln: 1.306 ± 1.193
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
1.306TrpVal: 1.306 ± 1.069
0.653TrpTrp: 0.653 ± 0.415
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.653TyrAla: 0.653 ± 0.596
1.306TyrCys: 1.306 ± 0.736
1.306TyrAsp: 1.306 ± 1.193
0.653TyrGlu: 0.653 ± 0.653
2.613TyrPhe: 2.613 ± 1.447
1.96TyrGly: 1.96 ± 1.108
1.96TyrHis: 1.96 ± 0.875
1.306TyrIle: 1.306 ± 0.946
3.266TyrLys: 3.266 ± 0.89
1.306TyrLeu: 1.306 ± 0.736
0.653TyrMet: 0.653 ± 0.415
0.653TyrAsn: 0.653 ± 0.596
0.653TyrPro: 0.653 ± 0.653
0.0TyrGln: 0.0 ± 0.0
3.266TyrArg: 3.266 ± 1.877
3.266TyrSer: 3.266 ± 1.104
1.306TyrThr: 1.306 ± 0.587
1.96TyrVal: 1.96 ± 0.823
0.0TyrTrp: 0.0 ± 0.0
0.653TyrTyr: 0.653 ± 0.596
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1532 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski