Amino acid dipepetide frequency for Armadillidium nasatum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.551AlaAla: 3.551 ± 0.042
0.939AlaCys: 0.939 ± 0.016
2.248AlaAsp: 2.248 ± 0.025
3.182AlaGlu: 3.182 ± 0.03
2.226AlaPhe: 2.226 ± 0.026
2.676AlaGly: 2.676 ± 0.028
1.122AlaHis: 1.122 ± 0.016
2.987AlaIle: 2.987 ± 0.026
3.311AlaLys: 3.311 ± 0.036
4.984AlaLeu: 4.984 ± 0.041
1.134AlaMet: 1.134 ± 0.016
2.312AlaAsn: 2.312 ± 0.022
2.251AlaPro: 2.251 ± 0.027
1.838AlaGln: 1.838 ± 0.024
2.212AlaArg: 2.212 ± 0.025
4.593AlaSer: 4.593 ± 0.04
2.86AlaThr: 2.86 ± 0.029
3.299AlaVal: 3.299 ± 0.029
0.472AlaTrp: 0.472 ± 0.011
1.463AlaTyr: 1.463 ± 0.021
0.0AlaXaa: 0.0 ± 0.0
Cys
0.838CysAla: 0.838 ± 0.014
0.492CysCys: 0.492 ± 0.014
1.216CysAsp: 1.216 ± 0.024
1.288CysGlu: 1.288 ± 0.022
0.911CysPhe: 0.911 ± 0.016
1.288CysGly: 1.288 ± 0.025
0.559CysHis: 0.559 ± 0.012
1.197CysIle: 1.197 ± 0.02
1.286CysLys: 1.286 ± 0.019
1.918CysLeu: 1.918 ± 0.024
0.365CysMet: 0.365 ± 0.01
1.101CysAsn: 1.101 ± 0.018
1.164CysPro: 1.164 ± 0.025
0.77CysGln: 0.77 ± 0.014
0.934CysArg: 0.934 ± 0.019
2.017CysSer: 2.017 ± 0.03
1.004CysThr: 1.004 ± 0.018
1.151CysVal: 1.151 ± 0.018
0.206CysTrp: 0.206 ± 0.007
0.655CysTyr: 0.655 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
2.431AspAla: 2.431 ± 0.025
1.042AspCys: 1.042 ± 0.019
3.704AspAsp: 3.704 ± 0.042
4.424AspGlu: 4.424 ± 0.041
2.548AspPhe: 2.548 ± 0.024
2.916AspGly: 2.916 ± 0.037
1.145AspHis: 1.145 ± 0.016
3.713AspIle: 3.713 ± 0.031
3.492AspLys: 3.492 ± 0.055
4.921AspLeu: 4.921 ± 0.035
1.131AspMet: 1.131 ± 0.015
2.56AspAsn: 2.56 ± 0.026
2.457AspPro: 2.457 ± 0.024
1.639AspGln: 1.639 ± 0.021
2.102AspArg: 2.102 ± 0.03
4.621AspSer: 4.621 ± 0.041
2.52AspThr: 2.52 ± 0.023
3.34AspVal: 3.34 ± 0.034
0.587AspTrp: 0.587 ± 0.014
1.843AspTyr: 1.843 ± 0.023
0.0AspXaa: 0.0 ± 0.0
Glu
3.847GluAla: 3.847 ± 0.032
1.3GluCys: 1.3 ± 0.024
4.659GluAsp: 4.659 ± 0.038
8.201GluGlu: 8.201 ± 0.111
2.49GluPhe: 2.49 ± 0.026
3.673GluGly: 3.673 ± 0.032
1.317GluHis: 1.317 ± 0.02
4.516GluIle: 4.516 ± 0.047
6.33GluLys: 6.33 ± 0.083
5.482GluLeu: 5.482 ± 0.04
1.648GluMet: 1.648 ± 0.019
4.734GluAsn: 4.734 ± 0.045
2.246GluPro: 2.246 ± 0.028
2.193GluGln: 2.193 ± 0.028
3.512GluArg: 3.512 ± 0.04
5.298GluSer: 5.298 ± 0.04
3.873GluThr: 3.873 ± 0.049
4.192GluVal: 4.192 ± 0.032
0.659GluTrp: 0.659 ± 0.013
2.057GluTyr: 2.057 ± 0.021
0.0GluXaa: 0.0 ± 0.0
Phe
2.019PheAla: 2.019 ± 0.024
1.024PheCys: 1.024 ± 0.015
2.33PheAsp: 2.33 ± 0.022
2.715PheGlu: 2.715 ± 0.029
1.958PhePhe: 1.958 ± 0.026
2.547PheGly: 2.547 ± 0.034
1.115PheHis: 1.115 ± 0.015
2.845PheIle: 2.845 ± 0.03
2.833PheLys: 2.833 ± 0.028
4.189PheLeu: 4.189 ± 0.036
0.928PheMet: 0.928 ± 0.015
2.157PheAsn: 2.157 ± 0.021
1.966PhePro: 1.966 ± 0.02
1.615PheGln: 1.615 ± 0.021
1.931PheArg: 1.931 ± 0.022
4.007PheSer: 4.007 ± 0.034
2.351PheThr: 2.351 ± 0.022
2.686PheVal: 2.686 ± 0.025
0.489PheTrp: 0.489 ± 0.011
1.64PheTyr: 1.64 ± 0.018
0.0PheXaa: 0.0 ± 0.0
Gly
2.733GlyAla: 2.733 ± 0.034
0.988GlyCys: 0.988 ± 0.017
2.718GlyAsp: 2.718 ± 0.068
3.448GlyGlu: 3.448 ± 0.044
2.489GlyPhe: 2.489 ± 0.029
4.275GlyGly: 4.275 ± 0.064
1.345GlyHis: 1.345 ± 0.021
3.376GlyIle: 3.376 ± 0.036
3.715GlyLys: 3.715 ± 0.034
4.444GlyLeu: 4.444 ± 0.041
1.18GlyMet: 1.18 ± 0.017
2.853GlyAsn: 2.853 ± 0.028
2.17GlyPro: 2.17 ± 0.055
1.723GlyGln: 1.723 ± 0.022
2.79GlyArg: 2.79 ± 0.032
4.799GlySer: 4.799 ± 0.047
3.02GlyThr: 3.02 ± 0.029
3.332GlyVal: 3.332 ± 0.031
0.632GlyTrp: 0.632 ± 0.013
1.857GlyTyr: 1.857 ± 0.024
0.0GlyXaa: 0.0 ± 0.0
His
0.97HisAla: 0.97 ± 0.016
0.589HisCys: 0.589 ± 0.013
1.016HisAsp: 1.016 ± 0.013
1.347HisGlu: 1.347 ± 0.017
1.122HisPhe: 1.122 ± 0.016
1.181HisGly: 1.181 ± 0.019
0.911HisHis: 0.911 ± 0.022
1.571HisIle: 1.571 ± 0.019
1.493HisLys: 1.493 ± 0.02
2.598HisLeu: 2.598 ± 0.026
0.627HisMet: 0.627 ± 0.014
1.174HisAsn: 1.174 ± 0.016
1.352HisPro: 1.352 ± 0.02
1.042HisGln: 1.042 ± 0.019
1.181HisArg: 1.181 ± 0.016
2.297HisSer: 2.297 ± 0.025
1.294HisThr: 1.294 ± 0.021
1.304HisVal: 1.304 ± 0.017
0.271HisTrp: 0.271 ± 0.007
0.906HisTyr: 0.906 ± 0.014
0.0HisXaa: 0.0 ± 0.0
Ile
3.037IleAla: 3.037 ± 0.027
1.425IleCys: 1.425 ± 0.019
3.202IleAsp: 3.202 ± 0.027
4.026IleGlu: 4.026 ± 0.043
2.99IlePhe: 2.99 ± 0.032
3.106IleGly: 3.106 ± 0.028
1.525IleHis: 1.525 ± 0.019
3.925IleIle: 3.925 ± 0.027
4.289IleLys: 4.289 ± 0.034
6.049IleLeu: 6.049 ± 0.05
1.302IleMet: 1.302 ± 0.017
3.384IleAsn: 3.384 ± 0.028
3.26IlePro: 3.26 ± 0.031
2.292IleGln: 2.292 ± 0.022
2.78IleArg: 2.78 ± 0.027
5.443IleSer: 5.443 ± 0.036
3.299IleThr: 3.299 ± 0.03
3.508IleVal: 3.508 ± 0.033
0.611IleTrp: 0.611 ± 0.011
2.194IleTyr: 2.194 ± 0.04
0.0IleXaa: 0.0 ± 0.0
Lys
3.393LysAla: 3.393 ± 0.032
1.529LysCys: 1.529 ± 0.031
4.096LysAsp: 4.096 ± 0.037
6.499LysGlu: 6.499 ± 0.07
2.849LysPhe: 2.849 ± 0.026
3.528LysGly: 3.528 ± 0.083
1.604LysHis: 1.604 ± 0.021
4.586LysIle: 4.586 ± 0.037
6.711LysLys: 6.711 ± 0.064
6.192LysLeu: 6.192 ± 0.048
1.704LysMet: 1.704 ± 0.019
4.143LysAsn: 4.143 ± 0.038
3.04LysPro: 3.04 ± 0.062
2.348LysGln: 2.348 ± 0.028
3.936LysArg: 3.936 ± 0.036
5.709LysSer: 5.709 ± 0.047
3.818LysThr: 3.818 ± 0.033
4.05LysVal: 4.05 ± 0.029
0.7LysTrp: 0.7 ± 0.012
2.497LysTyr: 2.497 ± 0.025
0.0LysXaa: 0.0 ± 0.0
Leu
4.719LeuAla: 4.719 ± 0.04
1.87LeuCys: 1.87 ± 0.021
4.518LeuAsp: 4.518 ± 0.036
6.203LeuGlu: 6.203 ± 0.047
3.782LeuPhe: 3.782 ± 0.034
4.505LeuGly: 4.505 ± 0.035
2.39LeuHis: 2.39 ± 0.025
5.211LeuIle: 5.211 ± 0.046
7.307LeuLys: 7.307 ± 0.055
8.773LeuLeu: 8.773 ± 0.064
1.976LeuMet: 1.976 ± 0.024
4.942LeuAsn: 4.942 ± 0.036
4.784LeuPro: 4.784 ± 0.037
4.081LeuGln: 4.081 ± 0.034
4.67LeuArg: 4.67 ± 0.038
8.1LeuSer: 8.1 ± 0.055
4.936LeuThr: 4.936 ± 0.037
4.918LeuVal: 4.918 ± 0.035
0.913LeuTrp: 0.913 ± 0.015
2.799LeuTyr: 2.799 ± 0.028
0.0LeuXaa: 0.0 ± 0.0
Met
1.348MetAla: 1.348 ± 0.015
0.394MetCys: 0.394 ± 0.009
1.184MetAsp: 1.184 ± 0.017
1.639MetGlu: 1.639 ± 0.017
0.914MetPhe: 0.914 ± 0.014
1.196MetGly: 1.196 ± 0.018
0.428MetHis: 0.428 ± 0.01
1.238MetIle: 1.238 ± 0.016
1.878MetLys: 1.878 ± 0.019
1.794MetLeu: 1.794 ± 0.022
0.598MetMet: 0.598 ± 0.013
1.225MetAsn: 1.225 ± 0.017
0.914MetPro: 0.914 ± 0.016
0.76MetGln: 0.76 ± 0.012
1.005MetArg: 1.005 ± 0.014
1.738MetSer: 1.738 ± 0.019
1.167MetThr: 1.167 ± 0.016
1.22MetVal: 1.22 ± 0.016
0.229MetTrp: 0.229 ± 0.006
0.669MetTyr: 0.669 ± 0.013
0.0MetXaa: 0.0 ± 0.0
Asn
2.43AsnAla: 2.43 ± 0.023
1.108AsnCys: 1.108 ± 0.017
2.692AsnAsp: 2.692 ± 0.027
3.853AsnGlu: 3.853 ± 0.035
2.576AsnPhe: 2.576 ± 0.024
2.841AsnGly: 2.841 ± 0.033
1.262AsnHis: 1.262 ± 0.016
4.162AsnIle: 4.162 ± 0.033
3.681AsnLys: 3.681 ± 0.034
5.181AsnLeu: 5.181 ± 0.04
1.21AsnMet: 1.21 ± 0.018
3.343AsnAsn: 3.343 ± 0.044
2.516AsnPro: 2.516 ± 0.025
1.927AsnGln: 1.927 ± 0.023
2.237AsnArg: 2.237 ± 0.024
5.045AsnSer: 5.045 ± 0.042
2.707AsnThr: 2.707 ± 0.026
3.264AsnVal: 3.264 ± 0.028
0.529AsnTrp: 0.529 ± 0.01
1.916AsnTyr: 1.916 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
2.157ProAla: 2.157 ± 0.025
0.763ProCys: 0.763 ± 0.019
2.435ProAsp: 2.435 ± 0.028
3.259ProGlu: 3.259 ± 0.04
2.117ProPhe: 2.117 ± 0.025
2.544ProGly: 2.544 ± 0.062
1.258ProHis: 1.258 ± 0.019
2.562ProIle: 2.562 ± 0.023
3.158ProLys: 3.158 ± 0.038
4.326ProLeu: 4.326 ± 0.038
0.838ProMet: 0.838 ± 0.016
2.476ProAsn: 2.476 ± 0.027
4.003ProPro: 4.003 ± 0.07
2.018ProGln: 2.018 ± 0.031
2.066ProArg: 2.066 ± 0.027
5.0ProSer: 5.0 ± 0.051
2.723ProThr: 2.723 ± 0.031
3.029ProVal: 3.029 ± 0.033
0.468ProTrp: 0.468 ± 0.01
1.595ProTyr: 1.595 ± 0.022
0.0ProXaa: 0.0 ± 0.0
Gln
1.846GlnAla: 1.846 ± 0.025
0.759GlnCys: 0.759 ± 0.015
1.72GlnAsp: 1.72 ± 0.018
2.712GlnGlu: 2.712 ± 0.032
1.406GlnPhe: 1.406 ± 0.019
1.789GlnGly: 1.789 ± 0.023
0.979GlnHis: 0.979 ± 0.016
2.348GlnIle: 2.348 ± 0.023
2.747GlnLys: 2.747 ± 0.03
3.247GlnLeu: 3.247 ± 0.032
0.948GlnMet: 0.948 ± 0.014
2.318GlnAsn: 2.318 ± 0.026
1.7GlnPro: 1.7 ± 0.035
2.179GlnGln: 2.179 ± 0.046
1.949GlnArg: 1.949 ± 0.021
2.866GlnSer: 2.866 ± 0.029
2.038GlnThr: 2.038 ± 0.025
2.15GlnVal: 2.15 ± 0.023
0.362GlnTrp: 0.362 ± 0.008
1.203GlnTyr: 1.203 ± 0.018
0.0GlnXaa: 0.0 ± 0.0
Arg
2.191ArgAla: 2.191 ± 0.024
0.907ArgCys: 0.907 ± 0.017
2.422ArgAsp: 2.422 ± 0.032
3.346ArgGlu: 3.346 ± 0.037
1.855ArgPhe: 1.855 ± 0.021
2.602ArgGly: 2.602 ± 0.041
1.311ArgHis: 1.311 ± 0.018
2.912ArgIle: 2.912 ± 0.024
4.149ArgLys: 4.149 ± 0.037
4.091ArgLeu: 4.091 ± 0.036
1.038ArgMet: 1.038 ± 0.015
2.666ArgAsn: 2.666 ± 0.028
2.133ArgPro: 2.133 ± 0.022
1.745ArgGln: 1.745 ± 0.019
3.29ArgArg: 3.29 ± 0.042
3.882ArgSer: 3.882 ± 0.039
2.38ArgThr: 2.38 ± 0.024
2.567ArgVal: 2.567 ± 0.024
0.518ArgTrp: 0.518 ± 0.011
1.52ArgTyr: 1.52 ± 0.019
0.0ArgXaa: 0.0 ± 0.0
Ser
4.099SerAla: 4.099 ± 0.044
1.763SerCys: 1.763 ± 0.026
4.849SerAsp: 4.849 ± 0.042
5.774SerGlu: 5.774 ± 0.051
3.994SerPhe: 3.994 ± 0.035
4.784SerGly: 4.784 ± 0.037
2.261SerHis: 2.261 ± 0.024
4.774SerIle: 4.774 ± 0.035
5.974SerLys: 5.974 ± 0.049
8.55SerLeu: 8.55 ± 0.048
1.583SerMet: 1.583 ± 0.019
4.884SerAsn: 4.884 ± 0.044
4.944SerPro: 4.944 ± 0.06
3.546SerGln: 3.546 ± 0.037
4.0SerArg: 4.0 ± 0.039
11.484SerSer: 11.484 ± 0.106
5.07SerThr: 5.07 ± 0.047
5.317SerVal: 5.317 ± 0.039
0.826SerTrp: 0.826 ± 0.013
2.773SerTyr: 2.773 ± 0.026
0.0SerXaa: 0.0 ± 0.0
Thr
2.76ThrAla: 2.76 ± 0.027
1.131ThrCys: 1.131 ± 0.02
2.637ThrAsp: 2.637 ± 0.035
3.533ThrGlu: 3.533 ± 0.054
2.457ThrPhe: 2.457 ± 0.022
2.917ThrGly: 2.917 ± 0.032
1.299ThrHis: 1.299 ± 0.017
3.166ThrIle: 3.166 ± 0.028
3.498ThrLys: 3.498 ± 0.03
5.19ThrLeu: 5.19 ± 0.039
1.044ThrMet: 1.044 ± 0.016
2.734ThrAsn: 2.734 ± 0.024
3.293ThrPro: 3.293 ± 0.036
1.916ThrGln: 1.916 ± 0.025
2.215ThrArg: 2.215 ± 0.022
5.542ThrSer: 5.542 ± 0.046
3.627ThrThr: 3.627 ± 0.067
3.347ThrVal: 3.347 ± 0.035
0.536ThrTrp: 0.536 ± 0.012
1.651ThrTyr: 1.651 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
3.307ValAla: 3.307 ± 0.033
1.325ValCys: 1.325 ± 0.019
3.142ValAsp: 3.142 ± 0.027
3.998ValGlu: 3.998 ± 0.045
2.541ValPhe: 2.541 ± 0.024
3.09ValGly: 3.09 ± 0.03
1.361ValHis: 1.361 ± 0.016
3.718ValIle: 3.718 ± 0.029
4.134ValLys: 4.134 ± 0.035
5.375ValLeu: 5.375 ± 0.041
1.298ValMet: 1.298 ± 0.018
3.137ValAsn: 3.137 ± 0.026
2.786ValPro: 2.786 ± 0.028
2.053ValGln: 2.053 ± 0.021
2.617ValArg: 2.617 ± 0.024
5.205ValSer: 5.205 ± 0.038
3.631ValThr: 3.631 ± 0.034
3.769ValVal: 3.769 ± 0.038
0.617ValTrp: 0.617 ± 0.011
1.826ValTyr: 1.826 ± 0.019
0.0ValXaa: 0.0 ± 0.0
Trp
0.495TrpAla: 0.495 ± 0.012
0.222TrpCys: 0.222 ± 0.007
0.546TrpAsp: 0.546 ± 0.012
0.638TrpGlu: 0.638 ± 0.011
0.436TrpPhe: 0.436 ± 0.01
0.595TrpGly: 0.595 ± 0.014
0.233TrpHis: 0.233 ± 0.007
0.659TrpIle: 0.659 ± 0.012
0.787TrpLys: 0.787 ± 0.013
0.972TrpLeu: 0.972 ± 0.016
0.266TrpMet: 0.266 ± 0.008
0.59TrpAsn: 0.59 ± 0.013
0.345TrpPro: 0.345 ± 0.01
0.382TrpGln: 0.382 ± 0.01
0.571TrpArg: 0.571 ± 0.011
0.759TrpSer: 0.759 ± 0.013
0.575TrpThr: 0.575 ± 0.012
0.611TrpVal: 0.611 ± 0.01
0.16TrpTrp: 0.16 ± 0.007
0.327TrpTyr: 0.327 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.489TyrAla: 1.489 ± 0.019
0.787TyrCys: 0.787 ± 0.014
1.802TyrAsp: 1.802 ± 0.02
2.142TyrGlu: 2.142 ± 0.021
1.685TyrPhe: 1.685 ± 0.02
1.833TyrGly: 1.833 ± 0.021
0.822TyrHis: 0.822 ± 0.015
2.184TyrIle: 2.184 ± 0.038
2.159TyrLys: 2.159 ± 0.023
3.121TyrLeu: 3.121 ± 0.027
0.72TyrMet: 0.72 ± 0.011
1.747TyrAsn: 1.747 ± 0.019
1.468TyrPro: 1.468 ± 0.021
1.199TyrGln: 1.199 ± 0.019
1.529TyrArg: 1.529 ± 0.02
2.844TyrSer: 2.844 ± 0.026
1.6TyrThr: 1.6 ± 0.02
1.877TyrVal: 1.877 ± 0.022
0.386TyrTrp: 0.386 ± 0.009
1.329TyrTyr: 1.329 ± 0.024
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 14427 proteins (5254146 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski