Amino acid dipepetide frequency for Torque teno virus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.083AlaAla: 3.083 ± 1.286
1.028AlaCys: 1.028 ± 1.956
0.0AlaAsp: 0.0 ± 0.0
2.055AlaGlu: 2.055 ± 3.912
2.055AlaPhe: 2.055 ± 1.578
2.055AlaGly: 2.055 ± 1.578
2.055AlaHis: 2.055 ± 3.912
3.083AlaIle: 3.083 ± 1.286
1.028AlaLys: 1.028 ± 0.498
2.055AlaLeu: 2.055 ± 1.578
1.028AlaMet: 1.028 ± 0.498
2.055AlaAsn: 2.055 ± 0.996
4.111AlaPro: 4.111 ± 3.157
1.028AlaGln: 1.028 ± 1.956
4.111AlaArg: 4.111 ± 3.802
2.055AlaSer: 2.055 ± 0.996
3.083AlaThr: 3.083 ± 1.495
1.028AlaVal: 1.028 ± 0.498
2.055AlaTrp: 2.055 ± 0.996
2.055AlaTyr: 2.055 ± 0.996
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.028CysGlu: 1.028 ± 4.15
0.0CysPhe: 0.0 ± 0.0
3.083CysGly: 3.083 ± 3.519
0.0CysHis: 0.0 ± 0.0
1.028CysIle: 1.028 ± 0.498
1.028CysLys: 1.028 ± 4.15
1.028CysLeu: 1.028 ± 1.956
1.028CysMet: 1.028 ± 0.498
0.0CysAsn: 0.0 ± 0.0
1.028CysPro: 1.028 ± 0.498
0.0CysGln: 0.0 ± 0.0
1.028CysArg: 1.028 ± 0.498
3.083CysSer: 3.083 ± 1.495
1.028CysThr: 1.028 ± 0.498
1.028CysVal: 1.028 ± 0.498
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.055AspAla: 2.055 ± 3.912
0.0AspCys: 0.0 ± 0.0
3.083AspAsp: 3.083 ± 1.286
5.139AspGlu: 5.139 ± 2.491
5.139AspPhe: 5.139 ± 1.211
3.083AspGly: 3.083 ± 3.519
1.028AspHis: 1.028 ± 0.498
3.083AspIle: 3.083 ± 1.495
0.0AspLys: 0.0 ± 0.0
5.139AspLeu: 5.139 ± 1.211
0.0AspMet: 0.0 ± 0.0
3.083AspAsn: 3.083 ± 3.519
5.139AspPro: 5.139 ± 2.491
2.055AspGln: 2.055 ± 0.996
3.083AspArg: 3.083 ± 3.622
4.111AspSer: 4.111 ± 1.993
4.111AspThr: 4.111 ± 3.437
1.028AspVal: 1.028 ± 1.956
2.055AspTrp: 2.055 ± 3.863
3.083AspTyr: 3.083 ± 1.495
0.0AspXaa: 0.0 ± 0.0
Glu
2.055GluAla: 2.055 ± 3.912
0.0GluCys: 0.0 ± 0.0
3.083GluAsp: 3.083 ± 1.286
6.166GluGlu: 6.166 ± 2.571
0.0GluPhe: 0.0 ± 0.0
6.166GluGly: 6.166 ± 2.571
1.028GluHis: 1.028 ± 0.498
0.0GluIle: 0.0 ± 0.0
1.028GluLys: 1.028 ± 0.498
5.139GluLeu: 5.139 ± 2.836
1.028GluMet: 1.028 ± 1.006
1.028GluAsn: 1.028 ± 0.498
1.028GluPro: 1.028 ± 1.956
2.055GluGln: 2.055 ± 0.996
2.055GluArg: 2.055 ± 1.578
2.055GluSer: 2.055 ± 3.863
1.028GluThr: 1.028 ± 0.498
3.083GluVal: 3.083 ± 1.495
0.0GluTrp: 0.0 ± 0.0
2.055GluTyr: 2.055 ± 3.863
0.0GluXaa: 0.0 ± 0.0
Phe
1.028PheAla: 1.028 ± 0.498
2.055PheCys: 2.055 ± 1.578
2.055PheAsp: 2.055 ± 0.996
1.028PheGlu: 1.028 ± 0.498
3.083PhePhe: 3.083 ± 1.286
5.139PheGly: 5.139 ± 1.211
1.028PheHis: 1.028 ± 0.498
0.0PheIle: 0.0 ± 0.0
4.111PheLys: 4.111 ± 7.727
4.111PheLeu: 4.111 ± 1.993
2.055PheMet: 2.055 ± 0.996
3.083PheAsn: 3.083 ± 1.495
3.083PhePro: 3.083 ± 1.495
5.139PheGln: 5.139 ± 2.491
2.055PheArg: 2.055 ± 0.996
9.25PheSer: 9.25 ± 6.736
3.083PheThr: 3.083 ± 1.495
2.055PheVal: 2.055 ± 1.578
0.0PheTrp: 0.0 ± 0.0
1.028PheTyr: 1.028 ± 1.956
0.0PheXaa: 0.0 ± 0.0
Gly
3.083GlyAla: 3.083 ± 3.519
2.055GlyCys: 2.055 ± 1.578
5.139GlyAsp: 5.139 ± 7.425
3.083GlyGlu: 3.083 ± 1.286
3.083GlyPhe: 3.083 ± 3.622
6.166GlyGly: 6.166 ± 4.735
0.0GlyHis: 0.0 ± 0.0
1.028GlyIle: 1.028 ± 0.498
2.055GlyLys: 2.055 ± 0.996
4.111GlyLeu: 4.111 ± 1.993
0.0GlyMet: 0.0 ± 0.0
4.111GlyAsn: 4.111 ± 1.993
6.166GlyPro: 6.166 ± 2.571
1.028GlyGln: 1.028 ± 1.956
5.139GlyArg: 5.139 ± 2.836
4.111GlySer: 4.111 ± 1.993
5.139GlyThr: 5.139 ± 1.211
0.0GlyVal: 0.0 ± 0.0
1.028GlyTrp: 1.028 ± 0.498
5.139GlyTyr: 5.139 ± 2.491
0.0GlyXaa: 0.0 ± 0.0
His
2.055HisAla: 2.055 ± 1.578
0.0HisCys: 0.0 ± 0.0
2.055HisAsp: 2.055 ± 1.578
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.028HisGly: 1.028 ± 0.498
0.0HisHis: 0.0 ± 0.0
3.083HisIle: 3.083 ± 1.286
0.0HisLys: 0.0 ± 0.0
1.028HisLeu: 1.028 ± 0.498
1.028HisMet: 1.028 ± 1.956
0.0HisAsn: 0.0 ± 0.0
3.083HisPro: 3.083 ± 1.495
1.028HisGln: 1.028 ± 0.498
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.028HisVal: 1.028 ± 0.498
1.028HisTrp: 1.028 ± 0.498
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.055IleAla: 2.055 ± 0.996
3.083IleCys: 3.083 ± 1.495
2.055IleAsp: 2.055 ± 0.996
0.0IleGlu: 0.0 ± 0.0
3.083IlePhe: 3.083 ± 3.622
1.028IleGly: 1.028 ± 0.498
1.028IleHis: 1.028 ± 1.956
3.083IleIle: 3.083 ± 1.495
3.083IleLys: 3.083 ± 1.495
4.111IleLeu: 4.111 ± 1.993
1.028IleMet: 1.028 ± 0.498
3.083IleAsn: 3.083 ± 1.286
5.139IlePro: 5.139 ± 2.491
2.055IleGln: 2.055 ± 0.996
4.111IleArg: 4.111 ± 1.145
2.055IleSer: 2.055 ± 0.996
1.028IleThr: 1.028 ± 0.498
3.083IleVal: 3.083 ± 1.495
0.0IleTrp: 0.0 ± 0.0
2.055IleTyr: 2.055 ± 0.996
0.0IleXaa: 0.0 ± 0.0
Lys
2.055LysAla: 2.055 ± 0.996
2.055LysCys: 2.055 ± 3.863
5.139LysAsp: 5.139 ± 2.491
2.055LysGlu: 2.055 ± 0.996
2.055LysPhe: 2.055 ± 0.996
2.055LysGly: 2.055 ± 0.996
0.0LysHis: 0.0 ± 0.0
2.055LysIle: 2.055 ± 3.863
7.194LysLys: 7.194 ± 2.696
3.083LysLeu: 3.083 ± 3.622
3.083LysMet: 3.083 ± 2.35
2.055LysAsn: 2.055 ± 0.996
3.083LysPro: 3.083 ± 1.495
8.222LysGln: 8.222 ± 6.873
7.194LysArg: 7.194 ± 1.807
3.083LysSer: 3.083 ± 1.495
3.083LysThr: 3.083 ± 1.495
2.055LysVal: 2.055 ± 1.578
1.028LysTrp: 1.028 ± 0.498
4.111LysTyr: 4.111 ± 1.993
0.0LysXaa: 0.0 ± 0.0
Leu
2.055LeuAla: 2.055 ± 1.578
0.0LeuCys: 0.0 ± 0.0
1.028LeuAsp: 1.028 ± 0.498
3.083LeuGlu: 3.083 ± 1.286
6.166LeuPhe: 6.166 ± 2.989
3.083LeuGly: 3.083 ± 3.622
5.139LeuHis: 5.139 ± 1.211
3.083LeuIle: 3.083 ± 1.495
3.083LeuLys: 3.083 ± 1.495
3.083LeuLeu: 3.083 ± 1.286
1.028LeuMet: 1.028 ± 0.498
2.055LeuAsn: 2.055 ± 0.996
4.111LeuPro: 4.111 ± 5.33
3.083LeuGln: 3.083 ± 3.519
3.083LeuArg: 3.083 ± 1.495
1.028LeuSer: 1.028 ± 0.498
5.139LeuThr: 5.139 ± 3.316
6.166LeuVal: 6.166 ± 1.455
2.055LeuTrp: 2.055 ± 1.578
5.139LeuTyr: 5.139 ± 2.491
0.0LeuXaa: 0.0 ± 0.0
Met
1.028MetAla: 1.028 ± 0.498
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
3.083MetPhe: 3.083 ± 1.286
1.028MetGly: 1.028 ± 0.498
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.055MetLys: 2.055 ± 0.996
1.028MetLeu: 1.028 ± 4.15
1.028MetMet: 1.028 ± 0.497
1.028MetAsn: 1.028 ± 0.498
1.028MetPro: 1.028 ± 0.498
1.028MetGln: 1.028 ± 0.498
1.028MetArg: 1.028 ± 1.956
2.055MetSer: 2.055 ± 1.578
1.028MetThr: 1.028 ± 4.15
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.028MetTyr: 1.028 ± 0.498
0.0MetXaa: 0.0 ± 0.0
Asn
3.083AsnAla: 3.083 ± 1.495
0.0AsnCys: 0.0 ± 0.0
4.111AsnAsp: 4.111 ± 3.437
2.055AsnGlu: 2.055 ± 0.996
3.083AsnPhe: 3.083 ± 1.495
1.028AsnGly: 1.028 ± 0.498
0.0AsnHis: 0.0 ± 0.0
4.111AsnIle: 4.111 ± 1.993
0.0AsnLys: 0.0 ± 0.0
1.028AsnLeu: 1.028 ± 0.498
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
5.139AsnPro: 5.139 ± 2.491
3.083AsnGln: 3.083 ± 3.519
2.055AsnArg: 2.055 ± 0.996
1.028AsnSer: 1.028 ± 1.956
4.111AsnThr: 4.111 ± 1.993
3.083AsnVal: 3.083 ± 1.286
0.0AsnTrp: 0.0 ± 0.0
3.083AsnTyr: 3.083 ± 1.495
0.0AsnXaa: 0.0 ± 0.0
Pro
5.139ProAla: 5.139 ± 4.841
1.028ProCys: 1.028 ± 0.498
6.166ProAsp: 6.166 ± 1.455
1.028ProGlu: 1.028 ± 1.956
5.139ProPhe: 5.139 ± 3.316
7.194ProGly: 7.194 ± 4.406
0.0ProHis: 0.0 ± 0.0
5.139ProIle: 5.139 ± 1.211
5.139ProLys: 5.139 ± 3.316
9.25ProLeu: 9.25 ± 3.857
0.0ProMet: 0.0 ± 0.0
1.028ProAsn: 1.028 ± 0.498
10.277ProPro: 10.277 ± 13.533
4.111ProGln: 4.111 ± 1.145
7.194ProArg: 7.194 ± 1.807
8.222ProSer: 8.222 ± 2.29
3.083ProThr: 3.083 ± 1.495
2.055ProVal: 2.055 ± 1.578
3.083ProTrp: 3.083 ± 4.224
4.111ProTyr: 4.111 ± 3.437
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
3.083GlnGlu: 3.083 ± 1.286
2.055GlnPhe: 2.055 ± 1.578
1.028GlnGly: 1.028 ± 1.956
0.0GlnHis: 0.0 ± 0.0
3.083GlnIle: 3.083 ± 1.495
4.111GlnLys: 4.111 ± 1.993
4.111GlnLeu: 4.111 ± 1.993
0.0GlnMet: 0.0 ± 0.0
3.083GlnAsn: 3.083 ± 1.495
5.139GlnPro: 5.139 ± 4.841
6.166GlnGln: 6.166 ± 2.989
5.139GlnArg: 5.139 ± 1.211
3.083GlnSer: 3.083 ± 3.622
3.083GlnThr: 3.083 ± 1.286
2.055GlnVal: 2.055 ± 0.996
5.139GlnTrp: 5.139 ± 3.4
1.028GlnTyr: 1.028 ± 0.498
0.0GlnXaa: 0.0 ± 0.0
Arg
1.028ArgAla: 1.028 ± 1.956
1.028ArgCys: 1.028 ± 0.498
5.139ArgAsp: 5.139 ± 2.491
3.083ArgGlu: 3.083 ± 1.495
5.139ArgPhe: 5.139 ± 2.491
4.111ArgGly: 4.111 ± 1.993
0.0ArgHis: 0.0 ± 0.0
4.111ArgIle: 4.111 ± 1.993
5.139ArgLys: 5.139 ± 2.836
1.028ArgLeu: 1.028 ± 0.498
2.055ArgMet: 2.055 ± 0.996
0.0ArgAsn: 0.0 ± 0.0
10.277ArgPro: 10.277 ± 8.852
3.083ArgGln: 3.083 ± 4.224
30.832ArgArg: 30.832 ± 14.946
2.055ArgSer: 2.055 ± 1.578
7.194ArgThr: 7.194 ± 3.487
3.083ArgVal: 3.083 ± 1.286
6.166ArgTrp: 6.166 ± 2.989
2.055ArgTyr: 2.055 ± 0.996
0.0ArgXaa: 0.0 ± 0.0
Ser
3.083SerAla: 3.083 ± 1.495
2.055SerCys: 2.055 ± 3.863
3.083SerAsp: 3.083 ± 1.286
1.028SerGlu: 1.028 ± 0.498
2.055SerPhe: 2.055 ± 0.996
3.083SerGly: 3.083 ± 1.286
2.055SerHis: 2.055 ± 0.996
3.083SerIle: 3.083 ± 1.495
5.139SerLys: 5.139 ± 2.491
5.139SerLeu: 5.139 ± 3.4
1.028SerMet: 1.028 ± 1.956
5.139SerAsn: 5.139 ± 3.316
5.139SerPro: 5.139 ± 2.491
3.083SerGln: 3.083 ± 1.495
2.055SerArg: 2.055 ± 0.996
7.194SerSer: 7.194 ± 2.696
5.139SerThr: 5.139 ± 1.211
3.083SerVal: 3.083 ± 4.224
0.0SerTrp: 0.0 ± 0.0
1.028SerTyr: 1.028 ± 0.498
0.0SerXaa: 0.0 ± 0.0
Thr
3.083ThrAla: 3.083 ± 1.495
0.0ThrCys: 0.0 ± 0.0
4.111ThrAsp: 4.111 ± 3.802
1.028ThrGlu: 1.028 ± 1.956
4.111ThrPhe: 4.111 ± 3.437
8.222ThrGly: 8.222 ± 3.986
0.0ThrHis: 0.0 ± 0.0
2.055ThrIle: 2.055 ± 0.996
10.277ThrLys: 10.277 ± 3.792
4.111ThrLeu: 4.111 ± 1.993
0.0ThrMet: 0.0 ± 0.0
1.028ThrAsn: 1.028 ± 0.498
2.055ThrPro: 2.055 ± 3.863
2.055ThrGln: 2.055 ± 0.996
1.028ThrArg: 1.028 ± 0.498
5.139ThrSer: 5.139 ± 1.211
5.139ThrThr: 5.139 ± 2.491
6.166ThrVal: 6.166 ± 2.989
1.028ThrTrp: 1.028 ± 0.498
3.083ThrTyr: 3.083 ± 1.495
0.0ThrXaa: 0.0 ± 0.0
Val
3.083ValAla: 3.083 ± 3.519
0.0ValCys: 0.0 ± 0.0
4.111ValAsp: 4.111 ± 1.993
2.055ValGlu: 2.055 ± 3.912
1.028ValPhe: 1.028 ± 0.498
1.028ValGly: 1.028 ± 1.956
0.0ValHis: 0.0 ± 0.0
2.055ValIle: 2.055 ± 0.996
6.166ValLys: 6.166 ± 2.989
1.028ValLeu: 1.028 ± 0.498
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
8.222ValPro: 8.222 ± 2.29
2.055ValGln: 2.055 ± 0.996
3.083ValArg: 3.083 ± 1.495
0.0ValSer: 0.0 ± 0.0
6.166ValThr: 6.166 ± 3.268
3.083ValVal: 3.083 ± 1.495
1.028ValTrp: 1.028 ± 0.498
2.055ValTyr: 2.055 ± 1.578
0.0ValXaa: 0.0 ± 0.0
Trp
1.028TrpAla: 1.028 ± 0.498
1.028TrpCys: 1.028 ± 0.498
3.083TrpAsp: 3.083 ± 3.622
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.028TrpGly: 1.028 ± 0.498
1.028TrpHis: 1.028 ± 0.498
1.028TrpIle: 1.028 ± 0.498
1.028TrpLys: 1.028 ± 4.15
0.0TrpLeu: 0.0 ± 0.0
1.028TrpMet: 1.028 ± 4.15
2.055TrpAsn: 2.055 ± 0.996
2.055TrpPro: 2.055 ± 1.578
0.0TrpGln: 0.0 ± 0.0
7.194TrpArg: 7.194 ± 2.383
2.055TrpSer: 2.055 ± 0.996
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
2.055TrpTrp: 2.055 ± 0.996
3.083TrpTyr: 3.083 ± 1.495
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.028TyrAla: 1.028 ± 0.498
0.0TyrCys: 0.0 ± 0.0
2.055TyrAsp: 2.055 ± 0.996
4.111TyrGlu: 4.111 ± 3.802
4.111TyrPhe: 4.111 ± 1.993
1.028TyrGly: 1.028 ± 0.498
2.055TyrHis: 2.055 ± 0.996
2.055TyrIle: 2.055 ± 0.996
3.083TyrLys: 3.083 ± 1.495
3.083TyrLeu: 3.083 ± 1.495
0.0TyrMet: 0.0 ± 0.0
6.166TyrAsn: 6.166 ± 1.455
3.083TyrPro: 3.083 ± 3.622
1.028TyrGln: 1.028 ± 0.498
5.139TyrArg: 5.139 ± 2.491
1.028TyrSer: 1.028 ± 0.498
2.055TyrThr: 2.055 ± 0.996
3.083TyrVal: 3.083 ± 1.495
1.028TyrTrp: 1.028 ± 0.498
1.028TyrTyr: 1.028 ± 4.15
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (974 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski