Amino acid dipepetide frequency for Whitefly-associated begomovirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.211AlaAla: 4.211 ± 1.832
1.053AlaCys: 1.053 ± 0.779
0.0AlaAsp: 0.0 ± 0.0
3.158AlaGlu: 3.158 ± 1.411
0.0AlaPhe: 0.0 ± 0.0
2.105AlaGly: 2.105 ± 0.735
1.053AlaHis: 1.053 ± 1.127
3.158AlaIle: 3.158 ± 1.453
3.158AlaLys: 3.158 ± 0.998
5.263AlaLeu: 5.263 ± 1.553
1.053AlaMet: 1.053 ± 0.701
4.211AlaAsn: 4.211 ± 1.195
4.211AlaPro: 4.211 ± 1.167
1.053AlaGln: 1.053 ± 0.701
7.368AlaArg: 7.368 ± 2.983
7.368AlaSer: 7.368 ± 1.42
4.211AlaThr: 4.211 ± 1.839
3.158AlaVal: 3.158 ± 1.517
0.0AlaTrp: 0.0 ± 0.0
2.105AlaTyr: 2.105 ± 1.125
0.0AlaXaa: 0.0 ± 0.0
Cys
1.053CysAla: 1.053 ± 0.701
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.053CysGlu: 1.053 ± 0.779
0.0CysPhe: 0.0 ± 0.0
1.053CysGly: 1.053 ± 1.127
0.0CysHis: 0.0 ± 0.0
1.053CysIle: 1.053 ± 0.779
2.105CysLys: 2.105 ± 0.735
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.053CysAsn: 1.053 ± 0.701
1.053CysPro: 1.053 ± 1.195
0.0CysGln: 0.0 ± 0.0
1.053CysArg: 1.053 ± 0.701
4.211CysSer: 4.211 ± 2.54
3.158CysThr: 3.158 ± 2.241
1.053CysVal: 1.053 ± 0.779
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.158AspAla: 3.158 ± 1.207
1.053AspCys: 1.053 ± 1.195
3.158AspAsp: 3.158 ± 2.145
2.105AspGlu: 2.105 ± 0.735
3.158AspPhe: 3.158 ± 1.207
2.105AspGly: 2.105 ± 1.403
0.0AspHis: 0.0 ± 0.0
3.158AspIle: 3.158 ± 2.241
0.0AspLys: 0.0 ± 0.0
4.211AspLeu: 4.211 ± 0.901
0.0AspMet: 0.0 ± 0.0
2.105AspAsn: 2.105 ± 1.244
0.0AspPro: 0.0 ± 0.0
2.105AspGln: 2.105 ± 1.433
5.263AspArg: 5.263 ± 1.53
5.263AspSer: 5.263 ± 1.31
2.105AspThr: 2.105 ± 1.169
4.211AspVal: 4.211 ± 1.469
1.053AspTrp: 1.053 ± 0.701
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.263GluAla: 5.263 ± 1.646
0.0GluCys: 0.0 ± 0.0
1.053GluAsp: 1.053 ± 1.234
4.211GluGlu: 4.211 ± 2.06
1.053GluPhe: 1.053 ± 1.127
7.368GluGly: 7.368 ± 3.868
0.0GluHis: 0.0 ± 0.0
1.053GluIle: 1.053 ± 1.234
4.211GluLys: 4.211 ± 2.805
3.158GluLeu: 3.158 ± 1.411
1.053GluMet: 1.053 ± 0.701
6.316GluAsn: 6.316 ± 2.749
1.053GluPro: 1.053 ± 0.779
3.158GluGln: 3.158 ± 1.342
1.053GluArg: 1.053 ± 0.701
3.158GluSer: 3.158 ± 1.506
0.0GluThr: 0.0 ± 0.0
1.053GluVal: 1.053 ± 1.195
4.211GluTrp: 4.211 ± 1.195
1.053GluTyr: 1.053 ± 0.701
0.0GluXaa: 0.0 ± 0.0
Phe
1.053PheAla: 1.053 ± 1.234
1.053PheCys: 1.053 ± 0.779
2.105PheAsp: 2.105 ± 0.735
1.053PheGlu: 1.053 ± 0.701
1.053PhePhe: 1.053 ± 0.701
2.105PheGly: 2.105 ± 0.735
2.105PheHis: 2.105 ± 1.13
2.105PheIle: 2.105 ± 1.403
2.105PheLys: 2.105 ± 2.468
3.158PheLeu: 3.158 ± 2.104
0.0PheMet: 0.0 ± 0.0
3.158PheAsn: 3.158 ± 1.046
2.105PhePro: 2.105 ± 1.13
5.263PheGln: 5.263 ± 0.704
1.053PheArg: 1.053 ± 1.234
2.105PheSer: 2.105 ± 1.13
2.105PheThr: 2.105 ± 1.13
0.0PheVal: 0.0 ± 0.0
3.158PheTrp: 3.158 ± 1.743
2.105PheTyr: 2.105 ± 1.558
0.0PheXaa: 0.0 ± 0.0
Gly
3.158GlyAla: 3.158 ± 2.104
3.158GlyCys: 3.158 ± 2.241
5.263GlyAsp: 5.263 ± 2.517
2.105GlyGlu: 2.105 ± 1.125
1.053GlyPhe: 1.053 ± 1.127
4.211GlyGly: 4.211 ± 1.469
2.105GlyHis: 2.105 ± 1.13
2.105GlyIle: 2.105 ± 0.735
5.263GlyLys: 5.263 ± 2.822
2.105GlyLeu: 2.105 ± 1.13
0.0GlyMet: 0.0 ± 0.0
3.158GlyAsn: 3.158 ± 0.999
3.158GlyPro: 3.158 ± 1.342
5.263GlyGln: 5.263 ± 1.284
5.263GlyArg: 5.263 ± 2.684
4.211GlySer: 4.211 ± 0.901
6.316GlyThr: 6.316 ± 1.255
4.211GlyVal: 4.211 ± 3.572
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.105HisAla: 2.105 ± 1.382
1.053HisCys: 1.053 ± 1.127
1.053HisAsp: 1.053 ± 0.779
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.053HisGly: 1.053 ± 1.127
1.053HisHis: 1.053 ± 1.127
1.053HisIle: 1.053 ± 1.127
2.105HisLys: 2.105 ± 1.382
4.211HisLeu: 4.211 ± 2.25
0.0HisMet: 0.0 ± 0.0
3.158HisAsn: 3.158 ± 1.411
1.053HisPro: 1.053 ± 0.701
3.158HisGln: 3.158 ± 0.998
3.158HisArg: 3.158 ± 2.241
0.0HisSer: 0.0 ± 0.0
2.105HisThr: 2.105 ± 1.558
2.105HisVal: 2.105 ± 0.735
1.053HisTrp: 1.053 ± 0.701
1.053HisTyr: 1.053 ± 0.701
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.053IleCys: 1.053 ± 0.701
3.158IleAsp: 3.158 ± 2.145
1.053IleGlu: 1.053 ± 0.701
1.053IlePhe: 1.053 ± 0.701
2.105IleGly: 2.105 ± 1.726
1.053IleHis: 1.053 ± 1.127
2.105IleIle: 2.105 ± 0.735
6.316IleLys: 6.316 ± 1.079
2.105IleLeu: 2.105 ± 1.558
0.0IleMet: 0.0 ± 0.0
1.053IleAsn: 1.053 ± 1.195
1.053IlePro: 1.053 ± 0.701
2.105IleGln: 2.105 ± 1.403
5.263IleArg: 5.263 ± 2.603
3.158IleSer: 3.158 ± 1.874
4.211IleThr: 4.211 ± 2.167
2.105IleVal: 2.105 ± 1.403
3.158IleTrp: 3.158 ± 1.756
6.316IleTyr: 6.316 ± 2.824
0.0IleXaa: 0.0 ± 0.0
Lys
3.158LysAla: 3.158 ± 1.146
0.0LysCys: 0.0 ± 0.0
2.105LysAsp: 2.105 ± 1.403
7.368LysGlu: 7.368 ± 4.909
4.211LysPhe: 4.211 ± 1.123
2.105LysGly: 2.105 ± 1.169
1.053LysHis: 1.053 ± 0.701
6.316LysIle: 6.316 ± 2.092
3.158LysLys: 3.158 ± 1.506
4.211LysLeu: 4.211 ± 1.832
0.0LysMet: 0.0 ± 0.0
5.263LysAsn: 5.263 ± 1.871
1.053LysPro: 1.053 ± 0.779
2.105LysGln: 2.105 ± 1.726
3.158LysArg: 3.158 ± 1.342
3.158LysSer: 3.158 ± 0.998
1.053LysThr: 1.053 ± 0.701
5.263LysVal: 5.263 ± 3.895
1.053LysTrp: 1.053 ± 0.701
2.105LysTyr: 2.105 ± 0.735
0.0LysXaa: 0.0 ± 0.0
Leu
1.053LeuAla: 1.053 ± 1.234
1.053LeuCys: 1.053 ± 0.701
5.263LeuAsp: 5.263 ± 1.524
4.211LeuGlu: 4.211 ± 1.573
5.263LeuPhe: 5.263 ± 2.569
5.263LeuGly: 5.263 ± 0.704
4.211LeuHis: 4.211 ± 2.25
4.211LeuIle: 4.211 ± 1.573
6.316LeuLys: 6.316 ± 2.414
5.263LeuLeu: 5.263 ± 1.321
1.053LeuMet: 1.053 ± 1.195
6.316LeuAsn: 6.316 ± 1.388
2.105LeuPro: 2.105 ± 1.13
2.105LeuGln: 2.105 ± 1.433
3.158LeuArg: 3.158 ± 1.756
5.263LeuSer: 5.263 ± 2.684
2.105LeuThr: 2.105 ± 1.403
4.211LeuVal: 4.211 ± 1.123
0.0LeuTrp: 0.0 ± 0.0
4.211LeuTyr: 4.211 ± 2.167
0.0LeuXaa: 0.0 ± 0.0
Met
2.105MetAla: 2.105 ± 1.558
1.053MetCys: 1.053 ± 0.779
3.158MetAsp: 3.158 ± 1.874
0.0MetGlu: 0.0 ± 0.0
2.105MetPhe: 2.105 ± 1.558
1.053MetGly: 1.053 ± 1.195
1.053MetHis: 1.053 ± 0.779
0.0MetIle: 0.0 ± 0.0
1.053MetLys: 1.053 ± 0.701
1.053MetLeu: 1.053 ± 1.127
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.105MetPro: 2.105 ± 0.735
1.053MetGln: 1.053 ± 0.701
1.053MetArg: 1.053 ± 0.779
0.0MetSer: 0.0 ± 0.0
2.105MetThr: 2.105 ± 1.764
0.0MetVal: 0.0 ± 0.0
1.053MetTrp: 1.053 ± 0.701
2.105MetTyr: 2.105 ± 1.382
0.0MetXaa: 0.0 ± 0.0
Asn
8.421AsnAla: 8.421 ± 2.639
1.053AsnCys: 1.053 ± 0.701
3.158AsnAsp: 3.158 ± 0.999
2.105AsnGlu: 2.105 ± 1.558
1.053AsnPhe: 1.053 ± 1.234
3.158AsnGly: 3.158 ± 1.756
5.263AsnHis: 5.263 ± 3.2
2.105AsnIle: 2.105 ± 0.735
3.158AsnLys: 3.158 ± 1.506
7.368AsnLeu: 7.368 ± 2.158
3.158AsnMet: 3.158 ± 1.509
2.105AsnAsn: 2.105 ± 1.382
4.211AsnPro: 4.211 ± 0.901
0.0AsnGln: 0.0 ± 0.0
2.105AsnArg: 2.105 ± 0.735
2.105AsnSer: 2.105 ± 1.272
2.105AsnThr: 2.105 ± 1.13
3.158AsnVal: 3.158 ± 1.411
1.053AsnTrp: 1.053 ± 0.701
5.263AsnTyr: 5.263 ± 1.284
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.053ProCys: 1.053 ± 0.779
2.105ProAsp: 2.105 ± 0.735
5.263ProGlu: 5.263 ± 2.569
1.053ProPhe: 1.053 ± 0.701
2.105ProGly: 2.105 ± 1.13
3.158ProHis: 3.158 ± 2.104
0.0ProIle: 0.0 ± 0.0
3.158ProLys: 3.158 ± 1.342
5.263ProLeu: 5.263 ± 1.524
2.105ProMet: 2.105 ± 1.558
2.105ProAsn: 2.105 ± 1.403
5.263ProPro: 5.263 ± 2.074
3.158ProGln: 3.158 ± 2.66
4.211ProArg: 4.211 ± 2.375
4.211ProSer: 4.211 ± 1.997
3.158ProThr: 3.158 ± 2.257
3.158ProVal: 3.158 ± 1.207
1.053ProTrp: 1.053 ± 0.779
1.053ProTyr: 1.053 ± 0.779
0.0ProXaa: 0.0 ± 0.0
Gln
3.158GlnAla: 3.158 ± 1.046
3.158GlnCys: 3.158 ± 1.506
3.158GlnAsp: 3.158 ± 2.145
3.158GlnGlu: 3.158 ± 1.207
1.053GlnPhe: 1.053 ± 0.701
2.105GlnGly: 2.105 ± 1.13
0.0GlnHis: 0.0 ± 0.0
3.158GlnIle: 3.158 ± 1.517
1.053GlnLys: 1.053 ± 0.701
4.211GlnLeu: 4.211 ± 2.506
0.0GlnMet: 0.0 ± 0.0
1.053GlnAsn: 1.053 ± 1.195
4.211GlnPro: 4.211 ± 2.459
1.053GlnGln: 1.053 ± 0.701
2.105GlnArg: 2.105 ± 1.244
3.158GlnSer: 3.158 ± 0.998
2.105GlnThr: 2.105 ± 1.169
4.211GlnVal: 4.211 ± 1.462
1.053GlnTrp: 1.053 ± 0.701
2.105GlnTyr: 2.105 ± 0.735
0.0GlnXaa: 0.0 ± 0.0
Arg
7.368ArgAla: 7.368 ± 2.558
0.0ArgCys: 0.0 ± 0.0
3.158ArgAsp: 3.158 ± 2.337
2.105ArgGlu: 2.105 ± 1.13
7.368ArgPhe: 7.368 ± 3.71
8.421ArgGly: 8.421 ± 2.21
1.053ArgHis: 1.053 ± 0.779
5.263ArgIle: 5.263 ± 1.501
1.053ArgLys: 1.053 ± 0.779
0.0ArgLeu: 0.0 ± 0.0
1.053ArgMet: 1.053 ± 1.062
1.053ArgAsn: 1.053 ± 0.779
5.263ArgPro: 5.263 ± 1.871
2.105ArgGln: 2.105 ± 2.468
10.526ArgArg: 10.526 ± 5.698
6.316ArgSer: 6.316 ± 1.731
6.316ArgThr: 6.316 ± 2.749
6.316ArgVal: 6.316 ± 1.418
0.0ArgTrp: 0.0 ± 0.0
1.053ArgTyr: 1.053 ± 0.701
0.0ArgXaa: 0.0 ± 0.0
Ser
4.211SerAla: 4.211 ± 2.26
0.0SerCys: 0.0 ± 0.0
3.158SerAsp: 3.158 ± 1.207
1.053SerGlu: 1.053 ± 0.779
2.105SerPhe: 2.105 ± 1.13
5.263SerGly: 5.263 ± 1.752
1.053SerHis: 1.053 ± 0.779
4.211SerIle: 4.211 ± 1.318
5.263SerLys: 5.263 ± 2.03
4.211SerLeu: 4.211 ± 2.06
2.105SerMet: 2.105 ± 1.424
7.368SerAsn: 7.368 ± 1.372
7.368SerPro: 7.368 ± 3.122
3.158SerGln: 3.158 ± 2.104
6.316SerArg: 6.316 ± 1.418
10.526SerSer: 10.526 ± 4.719
4.211SerThr: 4.211 ± 2.666
4.211SerVal: 4.211 ± 1.839
0.0SerTrp: 0.0 ± 0.0
5.263SerTyr: 5.263 ± 2.028
0.0SerXaa: 0.0 ± 0.0
Thr
3.158ThrAla: 3.158 ± 1.046
1.053ThrCys: 1.053 ± 1.195
1.053ThrAsp: 1.053 ± 1.234
1.053ThrGlu: 1.053 ± 0.779
0.0ThrPhe: 0.0 ± 0.0
3.158ThrGly: 3.158 ± 1.046
4.211ThrHis: 4.211 ± 2.487
2.105ThrIle: 2.105 ± 1.13
2.105ThrLys: 2.105 ± 1.403
4.211ThrLeu: 4.211 ± 1.167
3.158ThrMet: 3.158 ± 1.342
5.263ThrAsn: 5.263 ± 1.153
4.211ThrPro: 4.211 ± 1.358
3.158ThrGln: 3.158 ± 2.257
4.211ThrArg: 4.211 ± 2.392
4.211ThrSer: 4.211 ± 1.889
1.053ThrThr: 1.053 ± 1.234
4.211ThrVal: 4.211 ± 1.889
0.0ThrTrp: 0.0 ± 0.0
3.158ThrTyr: 3.158 ± 1.517
0.0ThrXaa: 0.0 ± 0.0
Val
2.105ValAla: 2.105 ± 1.13
0.0ValCys: 0.0 ± 0.0
1.053ValAsp: 1.053 ± 0.701
5.263ValGlu: 5.263 ± 1.906
2.105ValPhe: 2.105 ± 0.735
2.105ValGly: 2.105 ± 1.558
0.0ValHis: 0.0 ± 0.0
3.158ValIle: 3.158 ± 2.255
3.158ValLys: 3.158 ± 1.342
5.263ValLeu: 5.263 ± 2.411
3.158ValMet: 3.158 ± 2.337
5.263ValAsn: 5.263 ± 2.603
3.158ValPro: 3.158 ± 1.207
3.158ValGln: 3.158 ± 0.998
3.158ValArg: 3.158 ± 2.502
7.368ValSer: 7.368 ± 0.765
2.105ValThr: 2.105 ± 1.558
1.053ValVal: 1.053 ± 0.779
1.053ValTrp: 1.053 ± 1.234
7.368ValTyr: 7.368 ± 2.424
0.0ValXaa: 0.0 ± 0.0
Trp
1.053TrpAla: 1.053 ± 0.701
1.053TrpCys: 1.053 ± 1.195
0.0TrpAsp: 0.0 ± 0.0
1.053TrpGlu: 1.053 ± 1.234
0.0TrpPhe: 0.0 ± 0.0
1.053TrpGly: 1.053 ± 0.701
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.053TrpLys: 1.053 ± 0.701
1.053TrpLeu: 1.053 ± 0.779
1.053TrpMet: 1.053 ± 0.779
1.053TrpAsn: 1.053 ± 0.701
0.0TrpPro: 0.0 ± 0.0
1.053TrpGln: 1.053 ± 0.701
3.158TrpArg: 3.158 ± 1.743
1.053TrpSer: 1.053 ± 0.701
2.105TrpThr: 2.105 ± 1.125
3.158TrpVal: 3.158 ± 0.998
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.105TyrAla: 2.105 ± 1.558
0.0TyrCys: 0.0 ± 0.0
1.053TyrAsp: 1.053 ± 0.779
2.105TyrGlu: 2.105 ± 1.558
5.263TyrPhe: 5.263 ± 0.704
4.211TyrGly: 4.211 ± 1.462
2.105TyrHis: 2.105 ± 1.125
2.105TyrIle: 2.105 ± 1.382
2.105TyrLys: 2.105 ± 1.403
6.316TyrLeu: 6.316 ± 3.044
2.105TyrMet: 2.105 ± 1.26
2.105TyrAsn: 2.105 ± 0.735
0.0TyrPro: 0.0 ± 0.0
1.053TyrGln: 1.053 ± 0.701
3.158TyrArg: 3.158 ± 1.738
4.211TyrSer: 4.211 ± 1.167
2.105TyrThr: 2.105 ± 1.764
4.211TyrVal: 4.211 ± 2.167
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (951 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski