Amino acid dipepetide frequency for Celeribacter baekdonensis B30

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.561AlaAla: 14.561 ± 0.147	1.082AlaCys: 1.082 ± 0.026	6.398AlaAsp: 6.398 ± 0.112	7.506AlaGlu: 7.506 ± 0.086	4.517AlaPhe: 4.517 ± 0.059	9.489AlaGly: 9.489 ± 0.094	2.383AlaHis: 2.383 ± 0.045	5.986AlaIle: 5.986 ± 0.073	4.396AlaLys: 4.396 ± 0.069	13.621AlaLeu: 13.621 ± 0.139	3.745AlaMet: 3.745 ± 0.06	2.699AlaAsn: 2.699 ± 0.049	5.601AlaPro: 5.601 ± 0.081	4.535AlaGln: 4.535 ± 0.068	7.89AlaArg: 7.89 ± 0.087	5.741AlaSer: 5.741 ± 0.076	6.125AlaThr: 6.125 ± 0.077	8.011AlaVal: 8.011 ± 0.082	1.366AlaTrp: 1.366 ± 0.03	2.679AlaTyr: 2.679 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.105CysAla: 1.105 ± 0.031	0.114CysCys: 0.114 ± 0.009	0.647CysAsp: 0.647 ± 0.023	0.463CysGlu: 0.463 ± 0.016	0.337CysPhe: 0.337 ± 0.017	0.925CysGly: 0.925 ± 0.029	0.287CysHis: 0.287 ± 0.015	0.397CysIle: 0.397 ± 0.016	0.227CysLys: 0.227 ± 0.012	0.901CysLeu: 0.901 ± 0.024	0.154CysMet: 0.154 ± 0.011	0.193CysAsn: 0.193 ± 0.012	0.505CysPro: 0.505 ± 0.022	0.241CysGln: 0.241 ± 0.014	0.522CysArg: 0.522 ± 0.02	0.465CysSer: 0.465 ± 0.02	0.465CysThr: 0.465 ± 0.019	0.656CysVal: 0.656 ± 0.023	0.112CysTrp: 0.112 ± 0.009	0.197CysTyr: 0.197 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.023AspAla: 7.023 ± 0.107	0.495AspCys: 0.495 ± 0.02	3.232AspAsp: 3.232 ± 0.073	3.525AspGlu: 3.525 ± 0.062	2.355AspPhe: 2.355 ± 0.045	5.326AspGly: 5.326 ± 0.077	1.5AspHis: 1.5 ± 0.039	3.307AspIle: 3.307 ± 0.052	1.749AspLys: 1.749 ± 0.04	6.648AspLeu: 6.648 ± 0.082	1.858AspMet: 1.858 ± 0.038	1.29AspAsn: 1.29 ± 0.034	3.435AspPro: 3.435 ± 0.063	1.973AspGln: 1.973 ± 0.044	3.906AspArg: 3.906 ± 0.062	2.124AspSer: 2.124 ± 0.042	3.27AspThr: 3.27 ± 0.062	4.444AspVal: 4.444 ± 0.066	1.104AspTrp: 1.104 ± 0.032	1.529AspTyr: 1.529 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	7.944GluAla: 7.944 ± 0.097	0.366GluCys: 0.366 ± 0.017	3.455GluAsp: 3.455 ± 0.06	3.308GluGlu: 3.308 ± 0.064	1.948GluPhe: 1.948 ± 0.037	4.825GluGly: 4.825 ± 0.075	1.161GluHis: 1.161 ± 0.03	3.874GluIle: 3.874 ± 0.062	2.216GluLys: 2.216 ± 0.046	4.962GluLeu: 4.962 ± 0.071	1.946GluMet: 1.946 ± 0.038	1.782GluAsn: 1.782 ± 0.038	2.337GluPro: 2.337 ± 0.045	1.847GluGln: 1.847 ± 0.043	4.025GluArg: 4.025 ± 0.055	2.209GluSer: 2.209 ± 0.044	3.985GluThr: 3.985 ± 0.062	4.365GluVal: 4.365 ± 0.056	0.684GluTrp: 0.684 ± 0.024	1.049GluTyr: 1.049 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.553PheAla: 4.553 ± 0.061	0.412PheCys: 0.412 ± 0.018	3.057PheAsp: 3.057 ± 0.049	2.399PheGlu: 2.399 ± 0.045	1.557PhePhe: 1.557 ± 0.041	3.949PheGly: 3.949 ± 0.062	0.79PheHis: 0.79 ± 0.026	1.738PheIle: 1.738 ± 0.038	1.155PheLys: 1.155 ± 0.032	3.406PheLeu: 3.406 ± 0.053	0.982PheMet: 0.982 ± 0.032	1.059PheAsn: 1.059 ± 0.031	1.627PhePro: 1.627 ± 0.036	1.022PheGln: 1.022 ± 0.03	1.985PheArg: 1.985 ± 0.04	2.377PheSer: 2.377 ± 0.042	2.156PheThr: 2.156 ± 0.051	2.894PheVal: 2.894 ± 0.047	0.583PheTrp: 0.583 ± 0.025	0.97PheTyr: 0.97 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	9.556GlyAla: 9.556 ± 0.113	0.863GlyCys: 0.863 ± 0.028	4.622GlyAsp: 4.622 ± 0.074	4.563GlyGlu: 4.563 ± 0.065	3.817GlyPhe: 3.817 ± 0.062	7.021GlyGly: 7.021 ± 0.096	1.889GlyHis: 1.889 ± 0.041	4.573GlyIle: 4.573 ± 0.069	3.33GlyLys: 3.33 ± 0.059	9.14GlyLeu: 9.14 ± 0.089	2.619GlyMet: 2.619 ± 0.046	1.992GlyAsn: 1.992 ± 0.049	3.501GlyPro: 3.501 ± 0.063	3.093GlyGln: 3.093 ± 0.054	5.229GlyArg: 5.229 ± 0.067	4.142GlySer: 4.142 ± 0.06	4.827GlyThr: 4.827 ± 0.073	6.445GlyVal: 6.445 ± 0.076	1.322GlyTrp: 1.322 ± 0.038	2.345GlyTyr: 2.345 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.297HisAla: 2.297 ± 0.046	0.234HisCys: 0.234 ± 0.012	1.335HisAsp: 1.335 ± 0.038	1.076HisGlu: 1.076 ± 0.029	0.873HisPhe: 0.873 ± 0.027	1.892HisGly: 1.892 ± 0.038	0.617HisHis: 0.617 ± 0.027	1.095HisIle: 1.095 ± 0.032	0.61HisLys: 0.61 ± 0.021	2.147HisLeu: 2.147 ± 0.042	0.632HisMet: 0.632 ± 0.021	0.513HisAsn: 0.513 ± 0.02	1.432HisPro: 1.432 ± 0.036	0.607HisGln: 0.607 ± 0.022	1.358HisArg: 1.358 ± 0.04	1.022HisSer: 1.022 ± 0.033	0.918HisThr: 0.918 ± 0.028	1.62HisVal: 1.62 ± 0.03	0.362HisTrp: 0.362 ± 0.016	0.537HisTyr: 0.537 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	7.073IleAla: 7.073 ± 0.079	0.631IleCys: 0.631 ± 0.022	3.522IleAsp: 3.522 ± 0.056	3.74IleGlu: 3.74 ± 0.053	1.895IlePhe: 1.895 ± 0.044	5.094IleGly: 5.094 ± 0.063	1.019IleHis: 1.019 ± 0.03	2.425IleIle: 2.425 ± 0.049	1.776IleLys: 1.776 ± 0.038	5.155IleLeu: 5.155 ± 0.084	1.176IleMet: 1.176 ± 0.03	1.428IleAsn: 1.428 ± 0.034	2.406IlePro: 2.406 ± 0.041	1.306IleGln: 1.306 ± 0.034	3.067IleArg: 3.067 ± 0.049	3.365IleSer: 3.365 ± 0.05	3.187IleThr: 3.187 ± 0.057	4.027IleVal: 4.027 ± 0.064	0.732IleTrp: 0.732 ± 0.023	1.283IleTyr: 1.283 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	4.214LysAla: 4.214 ± 0.062	0.201LysCys: 0.201 ± 0.013	2.089LysAsp: 2.089 ± 0.043	1.814LysGlu: 1.814 ± 0.043	1.052LysPhe: 1.052 ± 0.028	3.102LysGly: 3.102 ± 0.052	0.698LysHis: 0.698 ± 0.028	2.011LysIle: 2.011 ± 0.049	1.369LysLys: 1.369 ± 0.04	3.271LysLeu: 3.271 ± 0.049	1.042LysMet: 1.042 ± 0.028	0.919LysAsn: 0.919 ± 0.03	1.913LysPro: 1.913 ± 0.05	0.978LysGln: 0.978 ± 0.032	2.39LysArg: 2.39 ± 0.053	2.021LysSer: 2.021 ± 0.046	2.299LysThr: 2.299 ± 0.041	2.506LysVal: 2.506 ± 0.053	0.439LysTrp: 0.439 ± 0.018	0.703LysTyr: 0.703 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	12.227LeuAla: 12.227 ± 0.116	1.001LeuCys: 1.001 ± 0.03	5.967LeuAsp: 5.967 ± 0.062	5.348LeuGlu: 5.348 ± 0.072	3.718LeuPhe: 3.718 ± 0.065	8.508LeuGly: 8.508 ± 0.088	1.842LeuHis: 1.842 ± 0.036	5.729LeuIle: 5.729 ± 0.075	3.756LeuLys: 3.756 ± 0.057	8.849LeuLeu: 8.849 ± 0.106	2.876LeuMet: 2.876 ± 0.053	2.786LeuAsn: 2.786 ± 0.048	5.307LeuPro: 5.307 ± 0.077	2.508LeuGln: 2.508 ± 0.044	6.481LeuArg: 6.481 ± 0.086	7.424LeuSer: 7.424 ± 0.078	6.344LeuThr: 6.344 ± 0.072	6.719LeuVal: 6.719 ± 0.085	1.266LeuTrp: 1.266 ± 0.035	2.042LeuTyr: 2.042 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	3.563MetAla: 3.563 ± 0.054	0.201MetCys: 0.201 ± 0.011	1.551MetAsp: 1.551 ± 0.032	1.397MetGlu: 1.397 ± 0.034	0.903MetPhe: 0.903 ± 0.028	2.397MetGly: 2.397 ± 0.047	0.486MetHis: 0.486 ± 0.02	1.728MetIle: 1.728 ± 0.034	1.135MetLys: 1.135 ± 0.029	2.652MetLeu: 2.652 ± 0.049	0.918MetMet: 0.918 ± 0.028	0.886MetAsn: 0.886 ± 0.027	1.571MetPro: 1.571 ± 0.035	0.905MetGln: 0.905 ± 0.029	1.914MetArg: 1.914 ± 0.039	2.095MetSer: 2.095 ± 0.037	2.3MetThr: 2.3 ± 0.039	1.984MetVal: 1.984 ± 0.045	0.267MetTrp: 0.267 ± 0.015	0.359MetTyr: 0.359 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.251AsnAla: 3.251 ± 0.051	0.26AsnCys: 0.26 ± 0.015	1.479AsnAsp: 1.479 ± 0.047	1.225AsnGlu: 1.225 ± 0.031	0.98AsnPhe: 0.98 ± 0.024	2.487AsnGly: 2.487 ± 0.042	0.553AsnHis: 0.553 ± 0.019	1.431AsnIle: 1.431 ± 0.033	0.749AsnLys: 0.749 ± 0.025	2.609AsnLeu: 2.609 ± 0.05	0.775AsnMet: 0.775 ± 0.026	0.627AsnAsn: 0.627 ± 0.023	1.755AsnPro: 1.755 ± 0.043	0.644AsnGln: 0.644 ± 0.026	1.602AsnArg: 1.602 ± 0.04	1.218AsnSer: 1.218 ± 0.035	1.487AsnThr: 1.487 ± 0.033	1.932AsnVal: 1.932 ± 0.041	0.454AsnTrp: 0.454 ± 0.02	0.638AsnTyr: 0.638 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	5.041ProAla: 5.041 ± 0.068	0.348ProCys: 0.348 ± 0.017	3.62ProAsp: 3.62 ± 0.06	4.063ProGlu: 4.063 ± 0.07	2.012ProPhe: 2.012 ± 0.042	3.931ProGly: 3.931 ± 0.06	1.137ProHis: 1.137 ± 0.031	2.431ProIle: 2.431 ± 0.037	2.0ProLys: 2.0 ± 0.04	4.576ProLeu: 4.576 ± 0.064	1.454ProMet: 1.454 ± 0.036	1.498ProAsn: 1.498 ± 0.033	2.083ProPro: 2.083 ± 0.055	1.591ProGln: 1.591 ± 0.036	2.668ProArg: 2.668 ± 0.054	2.736ProSer: 2.736 ± 0.051	2.621ProThr: 2.621 ± 0.045	3.994ProVal: 3.994 ± 0.065	0.639ProTrp: 0.639 ± 0.022	1.175ProTyr: 1.175 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.771GlnAla: 3.771 ± 0.061	0.221GlnCys: 0.221 ± 0.013	1.769GlnAsp: 1.769 ± 0.041	1.525GlnGlu: 1.525 ± 0.036	1.102GlnPhe: 1.102 ± 0.029	2.505GlnGly: 2.505 ± 0.045	0.611GlnHis: 0.611 ± 0.02	2.081GlnIle: 2.081 ± 0.043	1.207GlnLys: 1.207 ± 0.034	2.654GlnLeu: 2.654 ± 0.045	1.075GlnMet: 1.075 ± 0.03	1.033GlnAsn: 1.033 ± 0.027	1.534GlnPro: 1.534 ± 0.037	0.97GlnGln: 0.97 ± 0.031	1.96GlnArg: 1.96 ± 0.041	1.948GlnSer: 1.948 ± 0.039	1.963GlnThr: 1.963 ± 0.038	2.259GlnVal: 2.259 ± 0.042	0.402GlnTrp: 0.402 ± 0.019	0.595GlnTyr: 0.595 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	7.423ArgAla: 7.423 ± 0.085	0.481ArgCys: 0.481 ± 0.018	4.084ArgAsp: 4.084 ± 0.069	3.484ArgGlu: 3.484 ± 0.059	2.633ArgPhe: 2.633 ± 0.046	4.237ArgGly: 4.237 ± 0.058	1.505ArgHis: 1.505 ± 0.035	3.561ArgIle: 3.561 ± 0.053	2.251ArgLys: 2.251 ± 0.048	6.907ArgLeu: 6.907 ± 0.102	1.84ArgMet: 1.84 ± 0.037	1.626ArgAsn: 1.626 ± 0.029	2.992ArgPro: 2.992 ± 0.049	2.125ArgGln: 2.125 ± 0.044	4.309ArgArg: 4.309 ± 0.079	3.107ArgSer: 3.107 ± 0.051	2.908ArgThr: 2.908 ± 0.046	4.558ArgVal: 4.558 ± 0.068	0.822ArgTrp: 0.822 ± 0.027	1.524ArgTyr: 1.524 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	5.961SerAla: 5.961 ± 0.077	0.488SerCys: 0.488 ± 0.02	3.539SerAsp: 3.539 ± 0.053	3.38SerGlu: 3.38 ± 0.055	2.327SerPhe: 2.327 ± 0.045	5.445SerGly: 5.445 ± 0.072	1.201SerHis: 1.201 ± 0.03	2.637SerIle: 2.637 ± 0.049	1.798SerLys: 1.798 ± 0.038	5.413SerLeu: 5.413 ± 0.071	1.467SerMet: 1.467 ± 0.038	1.474SerAsn: 1.474 ± 0.033	2.554SerPro: 2.554 ± 0.044	1.736SerGln: 1.736 ± 0.042	3.15SerArg: 3.15 ± 0.055	2.821SerSer: 2.821 ± 0.052	2.856SerThr: 2.856 ± 0.046	4.07SerVal: 4.07 ± 0.063	0.634SerTrp: 0.634 ± 0.023	1.421SerTyr: 1.421 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	6.179ThrAla: 6.179 ± 0.076	0.498ThrCys: 0.498 ± 0.021	3.245ThrAsp: 3.245 ± 0.055	3.052ThrGlu: 3.052 ± 0.048	2.19ThrPhe: 2.19 ± 0.042	5.301ThrGly: 5.301 ± 0.065	1.293ThrHis: 1.293 ± 0.034	2.885ThrIle: 2.885 ± 0.058	1.785ThrLys: 1.785 ± 0.039	6.573ThrLeu: 6.573 ± 0.081	1.426ThrMet: 1.426 ± 0.035	1.376ThrAsn: 1.376 ± 0.036	3.693ThrPro: 3.693 ± 0.059	1.814ThrGln: 1.814 ± 0.042	3.482ThrArg: 3.482 ± 0.056	2.991ThrSer: 2.991 ± 0.045	3.025ThrThr: 3.025 ± 0.051	4.52ThrVal: 4.52 ± 0.071	0.71ThrTrp: 0.71 ± 0.025	1.385ThrTyr: 1.385 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	8.59ValAla: 8.59 ± 0.088	0.63ValCys: 0.63 ± 0.022	4.119ValAsp: 4.119 ± 0.059	4.511ValGlu: 4.511 ± 0.066	2.953ValPhe: 2.953 ± 0.048	5.262ValGly: 5.262 ± 0.074	1.333ValHis: 1.333 ± 0.036	4.594ValIle: 4.594 ± 0.066	2.403ValLys: 2.403 ± 0.047	7.468ValLeu: 7.468 ± 0.085	2.268ValMet: 2.268 ± 0.042	1.917ValAsn: 1.917 ± 0.043	3.629ValPro: 3.629 ± 0.053	2.086ValGln: 2.086 ± 0.045	3.98ValArg: 3.98 ± 0.057	4.635ValSer: 4.635 ± 0.077	4.796ValThr: 4.796 ± 0.068	5.568ValVal: 5.568 ± 0.075	0.908ValTrp: 0.908 ± 0.027	1.472ValTyr: 1.472 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.345TrpAla: 1.345 ± 0.036	0.127TrpCys: 0.127 ± 0.01	0.738TrpAsp: 0.738 ± 0.024	0.613TrpGlu: 0.613 ± 0.02	0.553TrpPhe: 0.553 ± 0.021	1.023TrpGly: 1.023 ± 0.025	0.36TrpHis: 0.36 ± 0.018	0.758TrpIle: 0.758 ± 0.027	0.439TrpLys: 0.439 ± 0.019	1.498TrpLeu: 1.498 ± 0.041	0.408TrpMet: 0.408 ± 0.017	0.421TrpAsn: 0.421 ± 0.019	0.642TrpPro: 0.642 ± 0.023	0.52TrpGln: 0.52 ± 0.024	0.998TrpArg: 0.998 ± 0.033	0.767TrpSer: 0.767 ± 0.024	0.738TrpThr: 0.738 ± 0.025	0.901TrpVal: 0.901 ± 0.028	0.189TrpTrp: 0.189 ± 0.013	0.297TrpTyr: 0.297 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.654TyrAla: 2.654 ± 0.051	0.259TyrCys: 0.259 ± 0.014	1.626TyrAsp: 1.626 ± 0.038	1.294TyrGlu: 1.294 ± 0.034	0.95TyrPhe: 0.95 ± 0.027	2.169TyrGly: 2.169 ± 0.043	0.512TyrHis: 0.512 ± 0.021	1.064TyrIle: 1.064 ± 0.029	0.679TyrLys: 0.679 ± 0.021	2.248TyrLeu: 2.248 ± 0.041	0.551TyrMet: 0.551 ± 0.022	0.635TyrAsn: 0.635 ± 0.023	1.102TyrPro: 1.102 ± 0.03	0.686TyrGln: 0.686 ± 0.019	1.463TyrArg: 1.463 ± 0.034	1.167TyrSer: 1.167 ± 0.035	1.151TyrThr: 1.151 ± 0.032	1.648TyrVal: 1.648 ± 0.038	0.34TyrTrp: 0.34 ± 0.016	0.599TyrTyr: 0.599 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4198 proteins (1288073 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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