Amino acid dipepetide frequency for Croton yellow vein mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.05AlaAla: 10.05 ± 3.994
1.675AlaCys: 1.675 ± 1.115
1.675AlaAsp: 1.675 ± 0.998
2.513AlaGlu: 2.513 ± 1.24
1.675AlaPhe: 1.675 ± 1.055
1.675AlaGly: 1.675 ± 0.665
0.838AlaHis: 0.838 ± 1.006
2.513AlaIle: 2.513 ± 0.825
5.025AlaLys: 5.025 ± 1.611
5.863AlaLeu: 5.863 ± 2.579
0.0AlaMet: 0.0 ± 0.0
1.675AlaAsn: 1.675 ± 0.665
3.35AlaPro: 3.35 ± 2.179
4.188AlaGln: 4.188 ± 1.771
4.188AlaArg: 4.188 ± 2.128
5.025AlaSer: 5.025 ± 1.228
3.35AlaThr: 3.35 ± 1.87
1.675AlaVal: 1.675 ± 1.01
1.675AlaTrp: 1.675 ± 0.665
0.838AlaTyr: 0.838 ± 0.858
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.675CysCys: 1.675 ± 1.492
0.0CysAsp: 0.0 ± 0.0
1.675CysGlu: 1.675 ± 0.938
1.675CysPhe: 1.675 ± 1.055
1.675CysGly: 1.675 ± 0.92
0.838CysHis: 0.838 ± 1.006
0.838CysIle: 0.838 ± 1.059
0.838CysLys: 0.838 ± 0.694
1.675CysLeu: 1.675 ± 0.998
0.838CysMet: 0.838 ± 0.746
1.675CysAsn: 1.675 ± 1.196
4.188CysPro: 4.188 ± 2.351
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.675CysSer: 1.675 ± 2.011
0.838CysThr: 0.838 ± 0.694
1.675CysVal: 1.675 ± 0.665
0.838CysTrp: 0.838 ± 0.858
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.35AspAla: 3.35 ± 1.199
0.0AspCys: 0.0 ± 0.0
1.675AspAsp: 1.675 ± 0.92
1.675AspGlu: 1.675 ± 0.665
1.675AspPhe: 1.675 ± 0.665
1.675AspGly: 1.675 ± 1.196
0.838AspHis: 0.838 ± 0.814
4.188AspIle: 4.188 ± 1.728
0.0AspLys: 0.0 ± 0.0
5.025AspLeu: 5.025 ± 2.42
0.0AspMet: 0.0 ± 0.0
2.513AspAsn: 2.513 ± 1.328
1.675AspPro: 1.675 ± 0.873
3.35AspGln: 3.35 ± 1.079
2.513AspArg: 2.513 ± 1.22
6.7AspSer: 6.7 ± 1.492
2.513AspThr: 2.513 ± 2.151
5.863AspVal: 5.863 ± 1.857
2.513AspTrp: 2.513 ± 1.181
1.675AspTyr: 1.675 ± 0.998
0.0AspXaa: 0.0 ± 0.0
Glu
4.188GluAla: 4.188 ± 1.556
0.0GluCys: 0.0 ± 0.0
1.675GluAsp: 1.675 ± 1.259
4.188GluGlu: 4.188 ± 1.718
3.35GluPhe: 3.35 ± 1.821
5.025GluGly: 5.025 ± 1.286
0.0GluHis: 0.0 ± 0.0
1.675GluIle: 1.675 ± 0.862
4.188GluLys: 4.188 ± 2.381
2.513GluLeu: 2.513 ± 1.19
0.0GluMet: 0.0 ± 0.0
4.188GluAsn: 4.188 ± 1.922
1.675GluPro: 1.675 ± 0.938
2.513GluGln: 2.513 ± 0.83
0.0GluArg: 0.0 ± 0.0
0.838GluSer: 0.838 ± 1.006
2.513GluThr: 2.513 ± 1.451
2.513GluVal: 2.513 ± 1.385
1.675GluTrp: 1.675 ± 0.92
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.675PheCys: 1.675 ± 0.665
3.35PheAsp: 3.35 ± 1.33
0.838PheGlu: 0.838 ± 0.746
0.0PhePhe: 0.0 ± 0.0
0.838PheGly: 0.838 ± 0.858
1.675PheHis: 1.675 ± 0.873
4.188PheIle: 4.188 ± 1.548
3.35PheLys: 3.35 ± 1.723
5.863PheLeu: 5.863 ± 2.417
0.838PheMet: 0.838 ± 0.598
2.513PheAsn: 2.513 ± 1.734
1.675PhePro: 1.675 ± 1.257
5.863PheGln: 5.863 ± 1.634
3.35PheArg: 3.35 ± 1.314
0.838PheSer: 0.838 ± 0.598
2.513PheThr: 2.513 ± 1.221
0.838PheVal: 0.838 ± 0.694
1.675PheTrp: 1.675 ± 0.998
1.675PheTyr: 1.675 ± 1.387
0.0PheXaa: 0.0 ± 0.0
Gly
1.675GlyAla: 1.675 ± 1.196
1.675GlyCys: 1.675 ± 1.115
4.188GlyAsp: 4.188 ± 1.984
2.513GlyGlu: 2.513 ± 1.067
1.675GlyPhe: 1.675 ± 1.257
3.35GlyGly: 3.35 ± 1.199
2.513GlyHis: 2.513 ± 0.83
4.188GlyIle: 4.188 ± 1.754
5.863GlyLys: 5.863 ± 2.482
2.513GlyLeu: 2.513 ± 1.393
0.838GlyMet: 0.838 ± 0.746
0.838GlyAsn: 0.838 ± 0.858
3.35GlyPro: 3.35 ± 1.584
2.513GlyGln: 2.513 ± 0.927
3.35GlyArg: 3.35 ± 1.223
3.35GlySer: 3.35 ± 1.913
2.513GlyThr: 2.513 ± 1.286
2.513GlyVal: 2.513 ± 1.836
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.513HisAla: 2.513 ± 0.83
1.675HisCys: 1.675 ± 1.257
0.838HisAsp: 0.838 ± 0.746
0.838HisGlu: 0.838 ± 1.059
2.513HisPhe: 2.513 ± 1.297
1.675HisGly: 1.675 ± 1.257
4.188HisHis: 4.188 ± 3.345
1.675HisIle: 1.675 ± 0.998
1.675HisLys: 1.675 ± 1.257
1.675HisLeu: 1.675 ± 0.998
0.838HisMet: 0.838 ± 0.694
5.025HisAsn: 5.025 ± 1.65
3.35HisPro: 3.35 ± 1.995
2.513HisGln: 2.513 ± 0.83
3.35HisArg: 3.35 ± 2.134
0.838HisSer: 0.838 ± 1.006
1.675HisThr: 1.675 ± 1.387
2.513HisVal: 2.513 ± 1.677
0.0HisTrp: 0.0 ± 0.0
0.838HisTyr: 0.838 ± 0.598
0.0HisXaa: 0.0 ± 0.0
Ile
2.513IleAla: 2.513 ± 2.235
2.513IleCys: 2.513 ± 1.06
2.513IleAsp: 2.513 ± 1.794
1.675IleGlu: 1.675 ± 1.196
3.35IlePhe: 3.35 ± 2.392
1.675IleGly: 1.675 ± 1.387
1.675IleHis: 1.675 ± 0.862
5.025IleIle: 5.025 ± 1.84
4.188IleLys: 4.188 ± 1.023
1.675IleLeu: 1.675 ± 0.998
0.838IleMet: 0.838 ± 0.931
1.675IleAsn: 1.675 ± 0.862
2.513IlePro: 2.513 ± 1.181
3.35IleGln: 3.35 ± 1.711
6.7IleArg: 6.7 ± 1.551
6.7IleSer: 6.7 ± 1.784
4.188IleThr: 4.188 ± 2.4
2.513IleVal: 2.513 ± 1.22
4.188IleTrp: 4.188 ± 2.089
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.35LysAla: 3.35 ± 1.697
2.513LysCys: 2.513 ± 1.24
2.513LysAsp: 2.513 ± 1.794
4.188LysGlu: 4.188 ± 1.509
2.513LysPhe: 2.513 ± 0.874
5.025LysGly: 5.025 ± 1.639
1.675LysHis: 1.675 ± 1.196
2.513LysIle: 2.513 ± 1.322
0.838LysLys: 0.838 ± 1.006
0.838LysLeu: 0.838 ± 0.598
0.0LysMet: 0.0 ± 0.0
6.7LysAsn: 6.7 ± 2.706
2.513LysPro: 2.513 ± 0.83
0.0LysGln: 0.0 ± 0.0
2.513LysArg: 2.513 ± 1.49
5.025LysSer: 5.025 ± 1.172
4.188LysThr: 4.188 ± 0.928
5.863LysVal: 5.863 ± 2.417
0.0LysTrp: 0.0 ± 0.0
3.35LysTyr: 3.35 ± 1.001
0.0LysXaa: 0.0 ± 0.0
Leu
2.513LeuAla: 2.513 ± 1.067
3.35LeuCys: 3.35 ± 1.626
3.35LeuAsp: 3.35 ± 1.631
2.513LeuGlu: 2.513 ± 1.794
0.838LeuPhe: 0.838 ± 0.598
4.188LeuGly: 4.188 ± 1.774
2.513LeuHis: 2.513 ± 1.443
4.188LeuIle: 4.188 ± 1.775
7.538LeuLys: 7.538 ± 2.268
1.675LeuLeu: 1.675 ± 1.387
1.675LeuMet: 1.675 ± 1.259
2.513LeuAsn: 2.513 ± 0.874
3.35LeuPro: 3.35 ± 2.002
1.675LeuGln: 1.675 ± 1.263
6.7LeuArg: 6.7 ± 3.302
2.513LeuSer: 2.513 ± 1.044
5.025LeuThr: 5.025 ± 1.912
1.675LeuVal: 1.675 ± 1.492
0.838LeuTrp: 0.838 ± 0.814
4.188LeuTyr: 4.188 ± 1.826
0.0LeuXaa: 0.0 ± 0.0
Met
0.838MetAla: 0.838 ± 0.694
0.0MetCys: 0.0 ± 0.0
1.675MetAsp: 1.675 ± 1.04
1.675MetGlu: 1.675 ± 1.11
1.675MetPhe: 1.675 ± 1.115
4.188MetGly: 4.188 ± 1.202
0.838MetHis: 0.838 ± 0.598
0.0MetIle: 0.0 ± 0.0
0.838MetLys: 0.838 ± 0.814
2.513MetLeu: 2.513 ± 1.246
0.838MetMet: 0.838 ± 1.059
0.0MetAsn: 0.0 ± 0.0
1.675MetPro: 1.675 ± 1.11
0.0MetGln: 0.0 ± 0.0
0.838MetArg: 0.838 ± 1.006
2.513MetSer: 2.513 ± 2.125
0.838MetThr: 0.838 ± 0.814
0.0MetVal: 0.0 ± 0.0
1.675MetTrp: 1.675 ± 0.873
2.513MetTyr: 2.513 ± 2.081
0.0MetXaa: 0.0 ± 0.0
Asn
4.188AsnAla: 4.188 ± 2.148
0.0AsnCys: 0.0 ± 0.0
5.025AsnAsp: 5.025 ± 1.805
2.513AsnGlu: 2.513 ± 1.286
2.513AsnPhe: 2.513 ± 0.927
1.675AsnGly: 1.675 ± 1.055
5.025AsnHis: 5.025 ± 2.249
4.188AsnIle: 4.188 ± 1.797
0.0AsnLys: 0.0 ± 0.0
5.863AsnLeu: 5.863 ± 2.258
0.838AsnMet: 0.838 ± 0.668
2.513AsnAsn: 2.513 ± 1.145
4.188AsnPro: 4.188 ± 1.168
0.838AsnGln: 0.838 ± 0.598
4.188AsnArg: 4.188 ± 1.404
3.35AsnSer: 3.35 ± 2.22
4.188AsnThr: 4.188 ± 1.023
3.35AsnVal: 3.35 ± 1.079
0.838AsnTrp: 0.838 ± 0.598
2.513AsnTyr: 2.513 ± 0.83
0.0AsnXaa: 0.0 ± 0.0
Pro
2.513ProAla: 2.513 ± 1.611
3.35ProCys: 3.35 ± 1.38
3.35ProAsp: 3.35 ± 1.12
2.513ProGlu: 2.513 ± 1.123
1.675ProPhe: 1.675 ± 0.862
1.675ProGly: 1.675 ± 0.998
2.513ProHis: 2.513 ± 1.297
5.025ProIle: 5.025 ± 1.286
4.188ProLys: 4.188 ± 2.148
2.513ProLeu: 2.513 ± 1.067
4.188ProMet: 4.188 ± 1.915
5.863ProAsn: 5.863 ± 1.783
2.513ProPro: 2.513 ± 1.19
0.838ProGln: 0.838 ± 1.006
4.188ProArg: 4.188 ± 1.556
8.375ProSer: 8.375 ± 3.176
2.513ProThr: 2.513 ± 1.19
4.188ProVal: 4.188 ± 1.732
0.0ProTrp: 0.0 ± 0.0
0.838ProTyr: 0.838 ± 0.694
0.0ProXaa: 0.0 ± 0.0
Gln
4.188GlnAla: 4.188 ± 1.282
0.0GlnCys: 0.0 ± 0.0
4.188GlnAsp: 4.188 ± 1.742
3.35GlnGlu: 3.35 ± 1.101
2.513GlnPhe: 2.513 ± 1.24
0.838GlnGly: 0.838 ± 0.598
1.675GlnHis: 1.675 ± 1.257
2.513GlnIle: 2.513 ± 1.24
1.675GlnLys: 1.675 ± 0.873
2.513GlnLeu: 2.513 ± 1.783
1.675GlnMet: 1.675 ± 0.92
0.838GlnAsn: 0.838 ± 0.814
3.35GlnPro: 3.35 ± 1.524
3.35GlnGln: 3.35 ± 1.115
1.675GlnArg: 1.675 ± 1.173
5.025GlnSer: 5.025 ± 0.938
2.513GlnThr: 2.513 ± 1.246
4.188GlnVal: 4.188 ± 1.282
0.0GlnTrp: 0.0 ± 0.0
1.675GlnTyr: 1.675 ± 0.665
0.0GlnXaa: 0.0 ± 0.0
Arg
1.675ArgAla: 1.675 ± 0.938
1.675ArgCys: 1.675 ± 1.492
3.35ArgAsp: 3.35 ± 1.48
2.513ArgGlu: 2.513 ± 1.278
4.188ArgPhe: 4.188 ± 2.209
3.35ArgGly: 3.35 ± 1.051
3.35ArgHis: 3.35 ± 1.278
3.35ArgIle: 3.35 ± 1.339
3.35ArgLys: 3.35 ± 1.572
2.513ArgLeu: 2.513 ± 0.927
1.675ArgMet: 1.675 ± 1.387
1.675ArgAsn: 1.675 ± 0.873
7.538ArgPro: 7.538 ± 1.315
1.675ArgGln: 1.675 ± 1.263
6.7ArgArg: 6.7 ± 3.709
6.7ArgSer: 6.7 ± 1.76
2.513ArgThr: 2.513 ± 1.19
5.863ArgVal: 5.863 ± 2.237
0.0ArgTrp: 0.0 ± 0.0
0.838ArgTyr: 0.838 ± 0.746
0.0ArgXaa: 0.0 ± 0.0
Ser
2.513SerAla: 2.513 ± 1.794
0.838SerCys: 0.838 ± 0.598
4.188SerAsp: 4.188 ± 1.603
0.838SerGlu: 0.838 ± 1.059
4.188SerPhe: 4.188 ± 1.071
2.513SerGly: 2.513 ± 0.927
0.0SerHis: 0.0 ± 0.0
4.188SerIle: 4.188 ± 1.772
5.863SerLys: 5.863 ± 1.94
4.188SerLeu: 4.188 ± 1.309
4.188SerMet: 4.188 ± 3.145
5.863SerAsn: 5.863 ± 2.166
6.7SerPro: 6.7 ± 2.229
3.35SerGln: 3.35 ± 1.242
5.025SerArg: 5.025 ± 2.189
13.4SerSer: 13.4 ± 4.367
6.7SerThr: 6.7 ± 1.265
5.025SerVal: 5.025 ± 1.884
0.0SerTrp: 0.0 ± 0.0
4.188SerTyr: 4.188 ± 0.885
0.0SerXaa: 0.0 ± 0.0
Thr
4.188ThrAla: 4.188 ± 1.023
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
1.675ThrGlu: 1.675 ± 0.665
0.838ThrPhe: 0.838 ± 0.598
4.188ThrGly: 4.188 ± 1.631
5.025ThrHis: 5.025 ± 1.923
0.838ThrIle: 0.838 ± 0.598
2.513ThrLys: 2.513 ± 1.22
4.188ThrLeu: 4.188 ± 1.202
0.838ThrMet: 0.838 ± 0.598
3.35ThrAsn: 3.35 ± 1.996
5.863ThrPro: 5.863 ± 1.344
4.188ThrGln: 4.188 ± 2.253
0.838ThrArg: 0.838 ± 0.694
5.025ThrSer: 5.025 ± 3.161
1.675ThrThr: 1.675 ± 1.325
7.538ThrVal: 7.538 ± 2.431
0.838ThrTrp: 0.838 ± 0.858
2.513ThrTyr: 2.513 ± 1.51
0.0ThrXaa: 0.0 ± 0.0
Val
0.838ValAla: 0.838 ± 0.598
0.0ValCys: 0.0 ± 0.0
3.35ValAsp: 3.35 ± 1.659
3.35ValGlu: 3.35 ± 2.02
3.35ValPhe: 3.35 ± 1.892
2.513ValGly: 2.513 ± 1.56
4.188ValHis: 4.188 ± 3.353
5.025ValIle: 5.025 ± 1.169
3.35ValLys: 3.35 ± 1.257
4.188ValLeu: 4.188 ± 3.29
0.838ValMet: 0.838 ± 0.694
5.025ValAsn: 5.025 ± 2.121
2.513ValPro: 2.513 ± 0.825
6.7ValGln: 6.7 ± 2.683
4.188ValArg: 4.188 ± 2.748
2.513ValSer: 2.513 ± 1.434
5.025ValThr: 5.025 ± 2.495
2.513ValVal: 2.513 ± 0.874
0.0ValTrp: 0.0 ± 0.0
5.863ValTyr: 5.863 ± 1.556
0.0ValXaa: 0.0 ± 0.0
Trp
5.863TrpAla: 5.863 ± 2.755
0.0TrpCys: 0.0 ± 0.0
0.838TrpAsp: 0.838 ± 0.746
0.838TrpGlu: 0.838 ± 0.814
0.0TrpPhe: 0.0 ± 0.0
0.838TrpGly: 0.838 ± 0.598
0.0TrpHis: 0.0 ± 0.0
0.838TrpIle: 0.838 ± 0.694
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.675TrpMet: 1.675 ± 1.04
0.838TrpAsn: 0.838 ± 0.814
0.838TrpPro: 0.838 ± 0.858
0.838TrpGln: 0.838 ± 0.598
0.838TrpArg: 0.838 ± 1.006
0.838TrpSer: 0.838 ± 1.006
0.838TrpThr: 0.838 ± 0.858
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.838TrpTyr: 0.838 ± 0.598
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.513TyrAla: 2.513 ± 1.472
0.0TyrCys: 0.0 ± 0.0
1.675TyrAsp: 1.675 ± 1.387
0.838TyrGlu: 0.838 ± 0.694
3.35TyrPhe: 3.35 ± 1.697
0.838TyrGly: 0.838 ± 0.598
0.838TyrHis: 0.838 ± 0.598
2.513TyrIle: 2.513 ± 1.403
0.838TyrLys: 0.838 ± 0.598
5.025TyrLeu: 5.025 ± 1.285
1.675TyrMet: 1.675 ± 1.024
2.513TyrAsn: 2.513 ± 0.83
0.838TyrPro: 0.838 ± 0.598
0.0TyrGln: 0.0 ± 0.0
3.35TyrArg: 3.35 ± 2.774
2.513TyrSer: 2.513 ± 1.24
0.0TyrThr: 0.0 ± 0.0
5.025TyrVal: 5.025 ± 1.739
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1195 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski