Amino acid dipepetide frequency for Cestrum yellow leaf curling virus (CmYLCV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.63AlaAla: 1.63 ± 0.86
0.0AlaCys: 0.0 ± 0.0
4.482AlaAsp: 4.482 ± 1.483
5.297AlaGlu: 5.297 ± 0.932
0.815AlaPhe: 0.815 ± 0.611
0.407AlaGly: 0.407 ± 0.306
0.407AlaHis: 0.407 ± 0.306
4.482AlaIle: 4.482 ± 0.686
4.075AlaLys: 4.075 ± 1.426
4.075AlaLeu: 4.075 ± 0.681
1.63AlaMet: 1.63 ± 1.076
4.075AlaAsn: 4.075 ± 1.313
2.852AlaPro: 2.852 ± 0.957
0.815AlaGln: 0.815 ± 0.533
2.445AlaArg: 2.445 ± 0.643
2.852AlaSer: 2.852 ± 0.758
4.075AlaThr: 4.075 ± 1.123
1.63AlaVal: 1.63 ± 0.654
0.0AlaTrp: 0.0 ± 0.0
2.037AlaTyr: 2.037 ± 0.68
0.0AlaXaa: 0.0 ± 0.0
Cys
0.407CysAla: 0.407 ± 0.306
0.407CysCys: 0.407 ± 0.345
1.222CysAsp: 1.222 ± 0.494
0.407CysGlu: 0.407 ± 0.345
0.815CysPhe: 0.815 ± 0.533
0.0CysGly: 0.0 ± 0.0
0.407CysHis: 0.407 ± 0.345
1.222CysIle: 1.222 ± 0.75
3.26CysLys: 3.26 ± 0.676
2.037CysLeu: 2.037 ± 1.187
0.407CysMet: 0.407 ± 0.475
0.407CysAsn: 0.407 ± 0.423
1.222CysPro: 1.222 ± 0.652
1.222CysGln: 1.222 ± 0.64
0.407CysArg: 0.407 ± 0.423
0.407CysSer: 0.407 ± 0.423
0.815CysThr: 0.815 ± 0.847
0.815CysVal: 0.815 ± 0.533
0.407CysTrp: 0.407 ± 0.345
0.815CysTyr: 0.815 ± 0.689
0.0CysXaa: 0.0 ± 0.0
Asp
2.445AspAla: 2.445 ± 1.108
0.407AspCys: 0.407 ± 0.345
1.222AspAsp: 1.222 ± 0.455
6.52AspGlu: 6.52 ± 1.859
2.445AspPhe: 2.445 ± 0.492
0.815AspGly: 0.815 ± 0.536
0.815AspHis: 0.815 ± 0.51
6.927AspIle: 6.927 ± 0.854
4.89AspLys: 4.89 ± 1.251
5.297AspLeu: 5.297 ± 1.555
0.815AspMet: 0.815 ± 0.56
1.63AspAsn: 1.63 ± 1.103
1.222AspPro: 1.222 ± 0.64
0.815AspGln: 0.815 ± 0.882
2.852AspArg: 2.852 ± 1.613
3.667AspSer: 3.667 ± 0.738
1.222AspThr: 1.222 ± 0.917
2.445AspVal: 2.445 ± 0.468
0.407AspTrp: 0.407 ± 0.34
2.037AspTyr: 2.037 ± 0.821
0.0AspXaa: 0.0 ± 0.0
Glu
2.445GluAla: 2.445 ± 1.167
1.63GluCys: 1.63 ± 0.72
5.705GluAsp: 5.705 ± 1.169
11.002GluGlu: 11.002 ± 3.415
4.075GluPhe: 4.075 ± 0.909
4.075GluGly: 4.075 ± 1.179
0.815GluHis: 0.815 ± 0.375
8.965GluIle: 8.965 ± 1.16
11.002GluLys: 11.002 ± 1.741
6.52GluLeu: 6.52 ± 1.978
2.852GluMet: 2.852 ± 1.154
5.297GluAsn: 5.297 ± 1.227
2.852GluPro: 2.852 ± 1.134
3.26GluGln: 3.26 ± 0.996
5.297GluArg: 5.297 ± 0.96
5.705GluSer: 5.705 ± 1.702
5.705GluThr: 5.705 ± 1.796
3.26GluVal: 3.26 ± 1.108
1.222GluTrp: 1.222 ± 0.513
1.63GluTyr: 1.63 ± 0.72
0.0GluXaa: 0.0 ± 0.0
Phe
2.852PheAla: 2.852 ± 1.036
0.815PheCys: 0.815 ± 0.375
1.63PheAsp: 1.63 ± 1.05
4.075PheGlu: 4.075 ± 1.143
0.407PhePhe: 0.407 ± 0.345
2.037PheGly: 2.037 ± 0.594
1.222PheHis: 1.222 ± 0.664
2.037PheIle: 2.037 ± 0.942
3.26PheLys: 3.26 ± 1.369
5.705PheLeu: 5.705 ± 1.053
1.63PheMet: 1.63 ± 0.404
0.815PheAsn: 0.815 ± 0.679
2.852PhePro: 2.852 ± 0.939
0.407PheGln: 0.407 ± 0.34
0.407PheArg: 0.407 ± 0.345
5.297PheSer: 5.297 ± 0.762
2.037PheThr: 2.037 ± 0.753
1.63PheVal: 1.63 ± 0.584
0.407PheTrp: 0.407 ± 0.345
2.445PheTyr: 2.445 ± 0.767
0.0PheXaa: 0.0 ± 0.0
Gly
2.445GlyAla: 2.445 ± 0.646
1.222GlyCys: 1.222 ± 0.591
0.815GlyAsp: 0.815 ± 0.462
2.445GlyGlu: 2.445 ± 0.759
4.075GlyPhe: 4.075 ± 1.146
2.445GlyGly: 2.445 ± 1.634
0.815GlyHis: 0.815 ± 0.389
2.852GlyIle: 2.852 ± 0.841
5.297GlyLys: 5.297 ± 1.597
5.297GlyLeu: 5.297 ± 1.037
0.407GlyMet: 0.407 ± 0.306
2.445GlyAsn: 2.445 ± 0.802
1.222GlyPro: 1.222 ± 0.644
0.815GlyGln: 0.815 ± 0.389
1.63GlyArg: 1.63 ± 0.403
1.222GlySer: 1.222 ± 0.477
1.63GlyThr: 1.63 ± 0.881
2.037GlyVal: 2.037 ± 1.065
0.0GlyTrp: 0.0 ± 0.0
1.222GlyTyr: 1.222 ± 0.317
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.407HisAsp: 0.407 ± 0.423
1.222HisGlu: 1.222 ± 0.652
0.407HisPhe: 0.407 ± 0.345
1.222HisGly: 1.222 ± 0.602
0.407HisHis: 0.407 ± 0.441
1.63HisIle: 1.63 ± 1.241
1.222HisLys: 1.222 ± 0.317
2.445HisLeu: 2.445 ± 0.906
0.0HisMet: 0.0 ± 0.0
0.815HisAsn: 0.815 ± 0.611
0.815HisPro: 0.815 ± 0.454
0.407HisGln: 0.407 ± 0.345
0.407HisArg: 0.407 ± 0.306
1.63HisSer: 1.63 ± 0.321
0.407HisThr: 0.407 ± 0.423
0.815HisVal: 0.815 ± 0.462
0.407HisTrp: 0.407 ± 0.306
0.815HisTyr: 0.815 ± 0.375
0.0HisXaa: 0.0 ± 0.0
Ile
5.705IleAla: 5.705 ± 1.959
1.63IleCys: 1.63 ± 0.973
4.075IleAsp: 4.075 ± 1.025
6.112IleGlu: 6.112 ± 0.932
4.075IlePhe: 4.075 ± 1.175
4.075IleGly: 4.075 ± 0.848
0.815IleHis: 0.815 ± 0.51
3.667IleIle: 3.667 ± 0.782
5.297IleLys: 5.297 ± 1.65
4.482IleLeu: 4.482 ± 1.588
0.407IleMet: 0.407 ± 0.345
6.112IleAsn: 6.112 ± 1.449
4.482IlePro: 4.482 ± 1.147
4.075IleGln: 4.075 ± 0.942
3.667IleArg: 3.667 ± 0.876
6.52IleSer: 6.52 ± 3.486
3.667IleThr: 3.667 ± 1.017
4.075IleVal: 4.075 ± 1.795
1.222IleTrp: 1.222 ± 0.591
2.037IleTyr: 2.037 ± 0.85
0.0IleXaa: 0.0 ± 0.0
Lys
4.89LysAla: 4.89 ± 1.29
2.445LysCys: 2.445 ± 1.277
8.15LysAsp: 8.15 ± 1.7
9.372LysGlu: 9.372 ± 1.934
5.705LysPhe: 5.705 ± 2.021
6.52LysGly: 6.52 ± 1.693
2.445LysHis: 2.445 ± 1.213
8.15LysIle: 8.15 ± 0.97
12.632LysLys: 12.632 ± 3.851
7.335LysLeu: 7.335 ± 1.806
2.445LysMet: 2.445 ± 0.635
4.482LysAsn: 4.482 ± 1.085
5.705LysPro: 5.705 ± 1.277
7.335LysGln: 7.335 ± 1.855
5.297LysArg: 5.297 ± 1.61
5.297LysSer: 5.297 ± 1.404
3.667LysThr: 3.667 ± 1.378
3.667LysVal: 3.667 ± 1.12
1.222LysTrp: 1.222 ± 0.591
3.667LysTyr: 3.667 ± 0.94
0.0LysXaa: 0.0 ± 0.0
Leu
4.89LeuAla: 4.89 ± 1.042
1.63LeuCys: 1.63 ± 0.54
4.482LeuAsp: 4.482 ± 1.496
11.41LeuGlu: 11.41 ± 3.062
5.297LeuPhe: 5.297 ± 1.107
1.63LeuGly: 1.63 ± 0.584
1.222LeuHis: 1.222 ± 0.739
3.667LeuIle: 3.667 ± 0.797
10.595LeuLys: 10.595 ± 2.478
4.075LeuLeu: 4.075 ± 0.944
2.852LeuMet: 2.852 ± 1.216
4.482LeuAsn: 4.482 ± 1.593
4.482LeuPro: 4.482 ± 0.644
6.927LeuGln: 6.927 ± 1.268
4.89LeuArg: 4.89 ± 2.076
5.297LeuSer: 5.297 ± 1.866
4.482LeuThr: 4.482 ± 1.459
4.482LeuVal: 4.482 ± 1.477
0.407LeuTrp: 0.407 ± 0.345
1.222LeuTyr: 1.222 ± 0.917
0.0LeuXaa: 0.0 ± 0.0
Met
1.63MetAla: 1.63 ± 1.359
0.0MetCys: 0.0 ± 0.0
1.222MetAsp: 1.222 ± 0.647
4.482MetGlu: 4.482 ± 1.502
0.815MetPhe: 0.815 ± 0.679
1.222MetGly: 1.222 ± 0.653
0.0MetHis: 0.0 ± 0.0
1.63MetIle: 1.63 ± 0.825
2.037MetLys: 2.037 ± 0.555
0.815MetLeu: 0.815 ± 0.389
0.815MetMet: 0.815 ± 0.389
0.815MetAsn: 0.815 ± 0.496
0.815MetPro: 0.815 ± 0.533
1.222MetGln: 1.222 ± 0.778
0.407MetArg: 0.407 ± 0.306
2.445MetSer: 2.445 ± 0.996
0.0MetThr: 0.0 ± 0.0
1.63MetVal: 1.63 ± 0.738
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.63AsnAla: 1.63 ± 0.863
2.037AsnCys: 2.037 ± 1.366
1.63AsnAsp: 1.63 ± 0.907
2.445AsnGlu: 2.445 ± 0.593
1.63AsnPhe: 1.63 ± 0.863
1.222AsnGly: 1.222 ± 0.439
0.815AsnHis: 0.815 ± 0.462
1.63AsnIle: 1.63 ± 0.907
4.89AsnLys: 4.89 ± 1.501
6.927AsnLeu: 6.927 ± 1.944
1.222AsnMet: 1.222 ± 0.734
2.852AsnAsn: 2.852 ± 0.413
3.26AsnPro: 3.26 ± 1.045
2.037AsnGln: 2.037 ± 0.814
1.63AsnArg: 1.63 ± 0.863
4.075AsnSer: 4.075 ± 0.899
3.26AsnThr: 3.26 ± 0.933
3.26AsnVal: 3.26 ± 0.78
0.407AsnTrp: 0.407 ± 0.306
4.075AsnTyr: 4.075 ± 1.526
0.0AsnXaa: 0.0 ± 0.0
Pro
4.075ProAla: 4.075 ± 0.861
0.0ProCys: 0.0 ± 0.0
1.63ProAsp: 1.63 ± 0.825
3.667ProGlu: 3.667 ± 0.696
1.63ProPhe: 1.63 ± 0.487
1.222ProGly: 1.222 ± 0.317
0.815ProHis: 0.815 ± 0.454
4.075ProIle: 4.075 ± 1.625
5.705ProLys: 5.705 ± 0.635
6.927ProLeu: 6.927 ± 1.619
0.0ProMet: 0.0 ± 0.0
2.445ProAsn: 2.445 ± 0.643
1.63ProPro: 1.63 ± 0.907
2.445ProGln: 2.445 ± 0.553
2.445ProArg: 2.445 ± 1.077
2.852ProSer: 2.852 ± 0.52
2.037ProThr: 2.037 ± 0.765
1.63ProVal: 1.63 ± 0.54
0.815ProTrp: 0.815 ± 0.495
0.815ProTyr: 0.815 ± 0.375
0.0ProXaa: 0.0 ± 0.0
Gln
0.407GlnAla: 0.407 ± 0.306
0.0GlnCys: 0.0 ± 0.0
2.037GlnAsp: 2.037 ± 0.861
6.112GlnGlu: 6.112 ± 1.008
1.63GlnPhe: 1.63 ± 0.634
2.037GlnGly: 2.037 ± 0.624
0.407GlnHis: 0.407 ± 0.423
3.667GlnIle: 3.667 ± 1.077
6.52GlnLys: 6.52 ± 0.855
5.297GlnLeu: 5.297 ± 1.288
1.63GlnMet: 1.63 ± 0.754
2.037GlnAsn: 2.037 ± 0.738
2.445GlnPro: 2.445 ± 0.814
1.222GlnGln: 1.222 ± 0.64
2.037GlnArg: 2.037 ± 1.109
2.852GlnSer: 2.852 ± 1.314
3.667GlnThr: 3.667 ± 1.245
0.815GlnVal: 0.815 ± 0.882
0.407GlnTrp: 0.407 ± 0.306
1.222GlnTyr: 1.222 ± 0.477
0.0GlnXaa: 0.0 ± 0.0
Arg
1.222ArgAla: 1.222 ± 0.695
0.407ArgCys: 0.407 ± 0.306
2.037ArgAsp: 2.037 ± 1.109
2.445ArgGlu: 2.445 ± 0.811
1.63ArgPhe: 1.63 ± 0.55
1.63ArgGly: 1.63 ± 0.778
0.407ArgHis: 0.407 ± 0.306
3.667ArgIle: 3.667 ± 1.232
6.112ArgLys: 6.112 ± 0.909
3.667ArgLeu: 3.667 ± 1.233
1.222ArgMet: 1.222 ± 0.603
3.26ArgAsn: 3.26 ± 1.843
0.407ArgPro: 0.407 ± 0.441
1.222ArgGln: 1.222 ± 0.454
2.445ArgArg: 2.445 ± 1.191
3.26ArgSer: 3.26 ± 1.111
4.075ArgThr: 4.075 ± 1.319
2.445ArgVal: 2.445 ± 1.326
0.407ArgTrp: 0.407 ± 0.306
0.407ArgTyr: 0.407 ± 0.345
0.0ArgXaa: 0.0 ± 0.0
Ser
2.852SerAla: 2.852 ± 0.955
2.445SerCys: 2.445 ± 0.492
2.445SerAsp: 2.445 ± 0.618
7.335SerGlu: 7.335 ± 2.543
1.63SerPhe: 1.63 ± 0.962
4.482SerGly: 4.482 ± 0.977
1.222SerHis: 1.222 ± 0.748
6.112SerIle: 6.112 ± 0.772
8.557SerLys: 8.557 ± 1.558
4.89SerLeu: 4.89 ± 1.608
0.0SerMet: 0.0 ± 0.0
2.037SerAsn: 2.037 ± 0.374
2.852SerPro: 2.852 ± 1.196
2.445SerGln: 2.445 ± 0.925
1.222SerArg: 1.222 ± 0.582
10.595SerSer: 10.595 ± 1.616
4.075SerThr: 4.075 ± 1.408
4.075SerVal: 4.075 ± 1.371
0.815SerTrp: 0.815 ± 0.389
2.852SerTyr: 2.852 ± 0.732
0.0SerXaa: 0.0 ± 0.0
Thr
2.445ThrAla: 2.445 ± 0.767
0.815ThrCys: 0.815 ± 0.536
2.445ThrAsp: 2.445 ± 0.687
3.26ThrGlu: 3.26 ± 0.957
1.63ThrPhe: 1.63 ± 0.686
3.667ThrGly: 3.667 ± 1.419
0.0ThrHis: 0.0 ± 0.0
5.297ThrIle: 5.297 ± 1.004
3.667ThrLys: 3.667 ± 1.069
4.482ThrLeu: 4.482 ± 1.76
1.63ThrMet: 1.63 ± 0.956
2.445ThrAsn: 2.445 ± 0.699
2.852ThrPro: 2.852 ± 0.586
4.075ThrGln: 4.075 ± 1.571
1.222ThrArg: 1.222 ± 0.606
4.482ThrSer: 4.482 ± 1.469
1.222ThrThr: 1.222 ± 0.971
2.445ThrVal: 2.445 ± 0.843
0.407ThrTrp: 0.407 ± 0.306
2.445ThrTyr: 2.445 ± 0.922
0.0ThrXaa: 0.0 ± 0.0
Val
2.852ValAla: 2.852 ± 0.582
1.222ValCys: 1.222 ± 0.587
2.445ValAsp: 2.445 ± 1.116
4.075ValGlu: 4.075 ± 0.914
1.63ValPhe: 1.63 ± 0.738
0.407ValGly: 0.407 ± 0.475
1.63ValHis: 1.63 ± 0.799
1.63ValIle: 1.63 ± 0.57
6.112ValLys: 6.112 ± 0.726
4.89ValLeu: 4.89 ± 1.17
1.222ValMet: 1.222 ± 0.954
2.037ValAsn: 2.037 ± 0.68
2.445ValPro: 2.445 ± 0.901
2.852ValGln: 2.852 ± 0.829
2.445ValArg: 2.445 ± 0.758
2.852ValSer: 2.852 ± 1.09
2.037ValThr: 2.037 ± 0.406
1.63ValVal: 1.63 ± 0.487
0.407ValTrp: 0.407 ± 0.34
0.815ValTyr: 0.815 ± 0.389
0.0ValXaa: 0.0 ± 0.0
Trp
0.815TrpAla: 0.815 ± 0.369
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.407TrpPhe: 0.407 ± 0.306
0.0TrpGly: 0.0 ± 0.0
0.815TrpHis: 0.815 ± 0.611
1.222TrpIle: 1.222 ± 0.477
2.445TrpLys: 2.445 ± 0.568
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.222TrpAsn: 1.222 ± 0.652
0.407TrpPro: 0.407 ± 0.423
0.815TrpGln: 0.815 ± 0.611
0.0TrpArg: 0.0 ± 0.0
0.815TrpSer: 0.815 ± 0.369
0.407TrpThr: 0.407 ± 0.345
0.407TrpVal: 0.407 ± 0.306
0.0TrpTrp: 0.0 ± 0.0
0.407TrpTyr: 0.407 ± 0.34
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.445TyrAla: 2.445 ± 1.273
0.0TyrCys: 0.0 ± 0.0
0.815TyrAsp: 0.815 ± 0.51
1.63TyrGlu: 1.63 ± 0.68
1.222TyrPhe: 1.222 ± 0.652
1.222TyrGly: 1.222 ± 0.75
0.0TyrHis: 0.0 ± 0.0
3.667TyrIle: 3.667 ± 1.337
2.852TyrLys: 2.852 ± 0.487
3.667TyrLeu: 3.667 ± 1.823
0.407TyrMet: 0.407 ± 0.345
1.222TyrAsn: 1.222 ± 0.317
2.037TyrPro: 2.037 ± 0.68
2.037TyrGln: 2.037 ± 0.749
1.222TyrArg: 1.222 ± 0.75
0.815TyrSer: 0.815 ± 0.375
2.445TyrThr: 2.445 ± 0.858
2.445TyrVal: 2.445 ± 1.108
0.815TyrTrp: 0.815 ± 0.454
0.407TyrTyr: 0.407 ± 0.345
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2455 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski