Amino acid dipepetide frequency for Sphaeropsis sapinea RNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.575AlaAla: 12.575 ± 0.436
2.395AlaCys: 2.395 ± 0.005
4.79AlaAsp: 4.79 ± 0.811
4.79AlaGlu: 4.79 ± 0.831
3.593AlaPhe: 3.593 ± 0.007
8.982AlaGly: 8.982 ± 1.25
4.79AlaHis: 4.79 ± 0.811
3.593AlaIle: 3.593 ± 0.813
2.395AlaLys: 2.395 ± 1.637
14.97AlaLeu: 14.97 ± 2.021
3.593AlaMet: 3.593 ± 0.813
4.79AlaAsn: 4.79 ± 0.831
6.587AlaPro: 6.587 ± 2.886
2.395AlaGln: 2.395 ± 0.826
11.377AlaArg: 11.377 ± 3.717
7.784AlaSer: 7.784 ± 0.394
5.389AlaThr: 5.389 ± 0.421
5.988AlaVal: 5.988 ± 0.833
1.796AlaTrp: 1.796 ± 0.407
2.994AlaTyr: 2.994 ± 0.404
0.0AlaXaa: 0.0 ± 0.0
Cys
1.796CysAla: 1.796 ± 0.414
0.599CysCys: 0.599 ± 0.412
2.994CysAsp: 2.994 ± 0.404
1.198CysGlu: 1.198 ± 0.818
0.599CysPhe: 0.599 ± 0.409
0.599CysGly: 0.599 ± 0.412
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.599CysLeu: 0.599 ± 0.409
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.198CysArg: 1.198 ± 0.002
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.198CysVal: 1.198 ± 0.002
0.0CysTrp: 0.0 ± 0.0
1.198CysTyr: 1.198 ± 0.002
0.0CysXaa: 0.0 ± 0.0
Asp
8.982AspAla: 8.982 ± 1.213
0.0AspCys: 0.0 ± 0.0
3.593AspAsp: 3.593 ± 0.813
1.198AspGlu: 1.198 ± 0.823
2.994AspPhe: 2.994 ± 0.404
4.79AspGly: 4.79 ± 0.831
0.599AspHis: 0.599 ± 0.409
2.395AspIle: 2.395 ± 0.826
1.198AspLys: 1.198 ± 0.818
3.593AspLeu: 3.593 ± 1.634
0.599AspMet: 0.599 ± 0.412
1.198AspAsn: 1.198 ± 0.823
4.192AspPro: 4.192 ± 0.402
1.198AspGln: 1.198 ± 0.823
3.593AspArg: 3.593 ± 0.813
2.994AspSer: 2.994 ± 0.417
3.593AspThr: 3.593 ± 0.007
5.389AspVal: 5.389 ± 0.399
0.0AspTrp: 0.0 ± 0.0
1.796AspTyr: 1.796 ± 0.407
0.0AspXaa: 0.0 ± 0.0
Glu
5.389GluAla: 5.389 ± 1.242
0.0GluCys: 0.0 ± 0.0
3.593GluAsp: 3.593 ± 0.828
1.796GluGlu: 1.796 ± 0.414
2.395GluPhe: 2.395 ± 0.005
2.994GluGly: 2.994 ± 1.237
2.994GluHis: 2.994 ± 0.417
0.599GluIle: 0.599 ± 0.412
0.599GluLys: 0.599 ± 0.412
4.79GluLeu: 4.79 ± 0.811
1.198GluMet: 1.198 ± 0.299
0.0GluAsn: 0.0 ± 0.0
2.395GluPro: 2.395 ± 0.005
1.796GluGln: 1.796 ± 0.414
3.593GluArg: 3.593 ± 0.007
1.198GluSer: 1.198 ± 0.002
1.796GluThr: 1.796 ± 1.227
1.796GluVal: 1.796 ± 0.407
1.198GluTrp: 1.198 ± 0.818
1.796GluTyr: 1.796 ± 0.407
0.0GluXaa: 0.0 ± 0.0
Phe
7.186PheAla: 7.186 ± 1.656
0.0PheCys: 0.0 ± 0.0
2.395PheAsp: 2.395 ± 0.005
1.198PheGlu: 1.198 ± 0.002
0.599PhePhe: 0.599 ± 0.409
4.79PheGly: 4.79 ± 0.811
0.599PheHis: 0.599 ± 0.409
1.198PheIle: 1.198 ± 0.002
0.0PheLys: 0.0 ± 0.0
3.593PheLeu: 3.593 ± 0.828
0.599PheMet: 0.599 ± 0.409
1.198PheAsn: 1.198 ± 0.818
4.192PhePro: 4.192 ± 0.419
0.0PheGln: 0.0 ± 0.0
3.593PheArg: 3.593 ± 0.007
1.796PheSer: 1.796 ± 0.407
1.198PheThr: 1.198 ± 0.823
3.593PheVal: 3.593 ± 0.813
0.599PheTrp: 0.599 ± 0.412
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.587GlyAla: 6.587 ± 1.245
1.198GlyCys: 1.198 ± 0.002
4.192GlyAsp: 4.192 ± 0.419
4.79GlyGlu: 4.79 ± 0.811
2.395GlyPhe: 2.395 ± 0.005
10.18GlyGly: 10.18 ± 2.894
5.389GlyHis: 5.389 ± 2.041
3.593GlyIle: 3.593 ± 0.007
2.395GlyLys: 2.395 ± 0.816
5.988GlyLeu: 5.988 ± 3.295
0.599GlyMet: 0.599 ± 0.412
1.796GlyAsn: 1.796 ± 0.407
8.383GlyPro: 8.383 ± 1.659
2.994GlyGln: 2.994 ± 0.417
8.383GlyArg: 8.383 ± 0.838
5.389GlySer: 5.389 ± 0.421
8.383GlyThr: 8.383 ± 0.838
2.994GlyVal: 2.994 ± 0.417
0.599GlyTrp: 0.599 ± 0.409
2.994GlyTyr: 2.994 ± 0.404
0.0GlyXaa: 0.0 ± 0.0
His
1.198HisAla: 1.198 ± 0.002
0.599HisCys: 0.599 ± 0.412
1.198HisAsp: 1.198 ± 0.002
1.198HisGlu: 1.198 ± 0.818
1.796HisPhe: 1.796 ± 0.407
2.395HisGly: 2.395 ± 1.637
1.198HisHis: 1.198 ± 0.002
0.599HisIle: 0.599 ± 0.409
0.0HisLys: 0.0 ± 0.0
3.593HisLeu: 3.593 ± 0.007
0.599HisMet: 0.599 ± 0.409
1.198HisAsn: 1.198 ± 0.002
2.994HisPro: 2.994 ± 0.404
1.198HisGln: 1.198 ± 0.823
1.796HisArg: 1.796 ± 1.227
4.79HisSer: 4.79 ± 0.811
3.593HisThr: 3.593 ± 0.007
1.796HisVal: 1.796 ± 1.227
0.599HisTrp: 0.599 ± 0.412
0.599HisTyr: 0.599 ± 0.412
0.0HisXaa: 0.0 ± 0.0
Ile
2.994IleAla: 2.994 ± 0.417
0.0IleCys: 0.0 ± 0.0
2.395IleAsp: 2.395 ± 0.816
2.395IleGlu: 2.395 ± 0.005
1.198IlePhe: 1.198 ± 0.002
1.198IleGly: 1.198 ± 0.002
1.796IleHis: 1.796 ± 1.235
1.198IleIle: 1.198 ± 0.818
0.599IleLys: 0.599 ± 0.409
3.593IleLeu: 3.593 ± 0.828
0.0IleMet: 0.0 ± 0.0
1.796IleAsn: 1.796 ± 0.407
2.994IlePro: 2.994 ± 2.058
0.599IleGln: 0.599 ± 0.412
4.192IleArg: 4.192 ± 1.223
3.593IleSer: 3.593 ± 0.813
2.994IleThr: 2.994 ± 0.417
2.994IleVal: 2.994 ± 0.404
0.0IleTrp: 0.0 ± 0.0
0.599IleTyr: 0.599 ± 0.409
0.0IleXaa: 0.0 ± 0.0
Lys
2.994LysAla: 2.994 ± 1.225
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
1.198LysGlu: 1.198 ± 0.002
0.599LysPhe: 0.599 ± 0.409
2.994LysGly: 2.994 ± 1.225
0.599LysHis: 0.599 ± 0.409
0.0LysIle: 0.0 ± 0.0
1.796LysLys: 1.796 ± 0.414
1.198LysLeu: 1.198 ± 0.818
1.198LysMet: 1.198 ± 0.818
1.198LysAsn: 1.198 ± 0.818
0.599LysPro: 0.599 ± 0.409
1.198LysGln: 1.198 ± 0.818
0.599LysArg: 0.599 ± 0.409
0.599LysSer: 0.599 ± 0.412
0.599LysThr: 0.599 ± 0.409
1.198LysVal: 1.198 ± 0.818
0.0LysTrp: 0.0 ± 0.0
0.599LysTyr: 0.599 ± 0.412
0.0LysXaa: 0.0 ± 0.0
Leu
12.575LeuAla: 12.575 ± 0.385
1.796LeuCys: 1.796 ± 1.227
5.389LeuAsp: 5.389 ± 1.22
1.796LeuGlu: 1.796 ± 0.414
3.593LeuPhe: 3.593 ± 1.649
10.18LeuGly: 10.18 ± 1.21
2.395LeuHis: 2.395 ± 1.637
3.593LeuIle: 3.593 ± 0.007
1.198LeuLys: 1.198 ± 0.002
13.174LeuLeu: 13.174 ± 1.615
2.395LeuMet: 2.395 ± 0.005
4.192LeuAsn: 4.192 ± 0.419
9.581LeuPro: 9.581 ± 0.02
1.198LeuGln: 1.198 ± 0.002
8.982LeuArg: 8.982 ± 0.392
5.988LeuSer: 5.988 ± 2.45
5.988LeuThr: 5.988 ± 0.012
7.186LeuVal: 7.186 ± 0.806
1.198LeuTrp: 1.198 ± 0.002
0.599LeuTyr: 0.599 ± 0.412
0.0LeuXaa: 0.0 ± 0.0
Met
3.593MetAla: 3.593 ± 0.813
0.0MetCys: 0.0 ± 0.0
0.599MetAsp: 0.599 ± 0.412
1.796MetGlu: 1.796 ± 0.414
0.0MetPhe: 0.0 ± 0.0
0.599MetGly: 0.599 ± 0.412
0.599MetHis: 0.599 ± 0.409
0.599MetIle: 0.599 ± 0.412
0.599MetLys: 0.599 ± 0.409
2.994MetLeu: 2.994 ± 1.225
0.0MetMet: 0.0 ± 0.0
0.599MetAsn: 0.599 ± 0.409
2.994MetPro: 2.994 ± 2.058
0.0MetGln: 0.0 ± 0.0
1.198MetArg: 1.198 ± 0.002
1.198MetSer: 1.198 ± 0.818
0.599MetThr: 0.599 ± 0.412
0.599MetVal: 0.599 ± 0.409
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.389AsnAla: 5.389 ± 0.421
0.599AsnCys: 0.599 ± 0.412
1.796AsnAsp: 1.796 ± 1.227
0.599AsnGlu: 0.599 ± 0.412
1.796AsnPhe: 1.796 ± 0.414
2.994AsnGly: 2.994 ± 1.237
1.198AsnHis: 1.198 ± 0.002
4.192AsnIle: 4.192 ± 1.223
0.599AsnLys: 0.599 ± 0.409
2.994AsnLeu: 2.994 ± 1.225
0.599AsnMet: 0.599 ± 0.412
0.599AsnAsn: 0.599 ± 0.409
3.593AsnPro: 3.593 ± 0.828
0.599AsnGln: 0.599 ± 0.409
2.994AsnArg: 2.994 ± 0.417
2.395AsnSer: 2.395 ± 0.816
1.198AsnThr: 1.198 ± 0.002
1.198AsnVal: 1.198 ± 0.823
0.599AsnTrp: 0.599 ± 0.409
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
8.383ProAla: 8.383 ± 0.017
1.198ProCys: 1.198 ± 0.823
5.988ProAsp: 5.988 ± 1.654
1.796ProGlu: 1.796 ± 0.414
2.994ProPhe: 2.994 ± 0.417
7.186ProGly: 7.186 ± 0.836
0.599ProHis: 0.599 ± 0.409
2.994ProIle: 2.994 ± 1.237
0.599ProLys: 0.599 ± 0.409
6.587ProLeu: 6.587 ± 0.397
1.198ProMet: 1.198 ± 0.823
3.593ProAsn: 3.593 ± 1.649
5.988ProPro: 5.988 ± 4.116
1.796ProGln: 1.796 ± 1.235
2.994ProArg: 2.994 ± 2.058
3.593ProSer: 3.593 ± 1.649
5.389ProThr: 5.389 ± 1.242
5.988ProVal: 5.988 ± 0.833
0.599ProTrp: 0.599 ± 0.409
1.796ProTyr: 1.796 ± 0.414
0.0ProXaa: 0.0 ± 0.0
Gln
2.395GlnAla: 2.395 ± 0.826
0.0GlnCys: 0.0 ± 0.0
1.198GlnAsp: 1.198 ± 0.002
1.796GlnGlu: 1.796 ± 1.235
0.599GlnPhe: 0.599 ± 0.409
1.796GlnGly: 1.796 ± 1.235
1.198GlnHis: 1.198 ± 0.823
0.599GlnIle: 0.599 ± 0.409
1.198GlnLys: 1.198 ± 0.818
0.599GlnLeu: 0.599 ± 0.412
0.599GlnMet: 0.599 ± 0.412
1.198GlnAsn: 1.198 ± 0.818
0.599GlnPro: 0.599 ± 0.412
0.0GlnGln: 0.0 ± 0.0
1.796GlnArg: 1.796 ± 0.407
2.395GlnSer: 2.395 ± 0.826
0.599GlnThr: 0.599 ± 0.409
2.395GlnVal: 2.395 ± 0.816
0.599GlnTrp: 0.599 ± 0.412
0.599GlnTyr: 0.599 ± 0.412
0.0GlnXaa: 0.0 ± 0.0
Arg
10.778ArgAla: 10.778 ± 1.619
0.599ArgCys: 0.599 ± 0.409
4.192ArgAsp: 4.192 ± 0.419
4.192ArgGlu: 4.192 ± 0.402
2.994ArgPhe: 2.994 ± 0.404
5.988ArgGly: 5.988 ± 2.475
2.994ArgHis: 2.994 ± 1.237
2.395ArgIle: 2.395 ± 0.005
1.796ArgLys: 1.796 ± 0.407
6.587ArgLeu: 6.587 ± 1.218
2.395ArgMet: 2.395 ± 1.637
2.395ArgAsn: 2.395 ± 0.005
5.389ArgPro: 5.389 ± 1.242
3.593ArgGln: 3.593 ± 0.007
4.192ArgArg: 4.192 ± 0.402
6.587ArgSer: 6.587 ± 3.68
2.994ArgThr: 2.994 ± 1.237
8.383ArgVal: 8.383 ± 1.659
1.796ArgTrp: 1.796 ± 0.407
2.395ArgTyr: 2.395 ± 0.826
0.0ArgXaa: 0.0 ± 0.0
Ser
5.389SerAla: 5.389 ± 1.242
1.796SerCys: 1.796 ± 0.407
1.796SerAsp: 1.796 ± 1.227
2.395SerGlu: 2.395 ± 1.637
3.593SerPhe: 3.593 ± 2.455
7.784SerGly: 7.784 ± 0.426
2.994SerHis: 2.994 ± 2.046
0.0SerIle: 0.0 ± 0.0
1.198SerLys: 1.198 ± 0.818
9.581SerLeu: 9.581 ± 0.84
1.198SerMet: 1.198 ± 0.823
1.796SerAsn: 1.796 ± 0.414
2.994SerPro: 2.994 ± 1.237
2.395SerGln: 2.395 ± 0.005
3.593SerArg: 3.593 ± 0.813
6.587SerSer: 6.587 ± 1.245
4.79SerThr: 4.79 ± 1.632
4.79SerVal: 4.79 ± 0.811
2.395SerTrp: 2.395 ± 0.816
1.198SerTyr: 1.198 ± 0.818
0.0SerXaa: 0.0 ± 0.0
Thr
5.988ThrAla: 5.988 ± 0.833
0.599ThrCys: 0.599 ± 0.409
3.593ThrAsp: 3.593 ± 0.007
1.796ThrGlu: 1.796 ± 0.414
1.796ThrPhe: 1.796 ± 1.235
4.192ThrGly: 4.192 ± 0.419
1.198ThrHis: 1.198 ± 0.002
3.593ThrIle: 3.593 ± 0.007
1.198ThrLys: 1.198 ± 0.002
5.988ThrLeu: 5.988 ± 0.012
0.599ThrMet: 0.599 ± 0.412
1.796ThrAsn: 1.796 ± 0.407
1.796ThrPro: 1.796 ± 0.407
1.198ThrGln: 1.198 ± 0.818
8.982ThrArg: 8.982 ± 2.034
4.79ThrSer: 4.79 ± 0.01
3.593ThrThr: 3.593 ± 0.828
2.994ThrVal: 2.994 ± 1.237
0.0ThrTrp: 0.0 ± 0.0
1.198ThrTyr: 1.198 ± 0.823
0.0ThrXaa: 0.0 ± 0.0
Val
8.383ValAla: 8.383 ± 0.838
0.0ValCys: 0.0 ± 0.0
2.395ValAsp: 2.395 ± 0.826
4.79ValGlu: 4.79 ± 0.01
2.395ValPhe: 2.395 ± 0.826
6.587ValGly: 6.587 ± 0.397
1.198ValHis: 1.198 ± 0.818
3.593ValIle: 3.593 ± 1.649
1.796ValLys: 1.796 ± 1.227
7.186ValLeu: 7.186 ± 0.806
0.599ValMet: 0.599 ± 0.297
5.389ValAsn: 5.389 ± 0.399
2.994ValPro: 2.994 ± 2.058
0.0ValGln: 0.0 ± 0.0
5.389ValArg: 5.389 ± 0.421
4.79ValSer: 4.79 ± 1.632
2.395ValThr: 2.395 ± 0.826
2.395ValVal: 2.395 ± 0.005
0.0ValTrp: 0.0 ± 0.0
2.395ValTyr: 2.395 ± 1.637
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.599TrpCys: 0.599 ± 0.409
0.599TrpAsp: 0.599 ± 0.409
0.599TrpGlu: 0.599 ± 0.412
1.198TrpPhe: 1.198 ± 0.823
0.599TrpGly: 0.599 ± 0.409
0.0TrpHis: 0.0 ± 0.0
0.599TrpIle: 0.599 ± 0.409
0.0TrpLys: 0.0 ± 0.0
2.994TrpLeu: 2.994 ± 1.225
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.599TrpPro: 0.599 ± 0.409
0.0TrpGln: 0.0 ± 0.0
0.599TrpArg: 0.599 ± 0.409
0.599TrpSer: 0.599 ± 0.409
0.599TrpThr: 0.599 ± 0.409
1.198TrpVal: 1.198 ± 0.823
0.599TrpTrp: 0.599 ± 0.409
1.198TrpTyr: 1.198 ± 0.002
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.994TyrAla: 2.994 ± 0.404
0.0TyrCys: 0.0 ± 0.0
1.198TyrAsp: 1.198 ± 0.002
1.198TyrGlu: 1.198 ± 0.823
1.198TyrPhe: 1.198 ± 0.002
2.395TyrGly: 2.395 ± 0.005
0.599TyrHis: 0.599 ± 0.412
1.796TyrIle: 1.796 ± 0.407
0.0TyrLys: 0.0 ± 0.0
2.395TyrLeu: 2.395 ± 0.816
0.0TyrMet: 0.0 ± 0.0
1.198TyrAsn: 1.198 ± 0.002
2.395TyrPro: 2.395 ± 0.826
0.0TyrGln: 0.0 ± 0.0
3.593TyrArg: 3.593 ± 0.813
1.198TyrSer: 1.198 ± 0.002
1.198TyrThr: 1.198 ± 0.818
0.599TyrVal: 0.599 ± 0.412
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1671 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski