Amino acid dipepetide frequency for Aerococcus viridans ATCC 11563 = CCUG 4311

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.323AlaAla: 6.323 ± 0.14
0.408AlaCys: 0.408 ± 0.023
5.434AlaAsp: 5.434 ± 0.105
5.602AlaGlu: 5.602 ± 0.11
3.493AlaPhe: 3.493 ± 0.097
5.912AlaGly: 5.912 ± 0.131
1.381AlaHis: 1.381 ± 0.054
6.764AlaIle: 6.764 ± 0.119
5.014AlaLys: 5.014 ± 0.1
7.723AlaLeu: 7.723 ± 0.125
2.154AlaMet: 2.154 ± 0.074
3.985AlaAsn: 3.985 ± 0.084
2.153AlaPro: 2.153 ± 0.066
2.98AlaGln: 2.98 ± 0.087
2.903AlaArg: 2.903 ± 0.073
4.932AlaSer: 4.932 ± 0.128
4.564AlaThr: 4.564 ± 0.099
5.679AlaVal: 5.679 ± 0.115
0.592AlaTrp: 0.592 ± 0.032
3.154AlaTyr: 3.154 ± 0.074
0.0AlaXaa: 0.0 ± 0.0
Cys
0.303CysAla: 0.303 ± 0.022
0.039CysCys: 0.039 ± 0.008
0.25CysAsp: 0.25 ± 0.022
0.254CysGlu: 0.254 ± 0.021
0.208CysPhe: 0.208 ± 0.019
0.462CysGly: 0.462 ± 0.027
0.145CysHis: 0.145 ± 0.015
0.256CysIle: 0.256 ± 0.022
0.212CysLys: 0.212 ± 0.018
0.375CysLeu: 0.375 ± 0.031
0.114CysMet: 0.114 ± 0.013
0.198CysAsn: 0.198 ± 0.018
0.2CysPro: 0.2 ± 0.024
0.224CysGln: 0.224 ± 0.024
0.194CysArg: 0.194 ± 0.018
0.27CysSer: 0.27 ± 0.026
0.198CysThr: 0.198 ± 0.02
0.313CysVal: 0.313 ± 0.026
0.025CysTrp: 0.025 ± 0.007
0.123CysTyr: 0.123 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
4.701AspAla: 4.701 ± 0.109
0.266AspCys: 0.266 ± 0.022
3.78AspAsp: 3.78 ± 0.103
5.021AspGlu: 5.021 ± 0.109
3.127AspPhe: 3.127 ± 0.078
3.945AspGly: 3.945 ± 0.102
1.435AspHis: 1.435 ± 0.05
4.941AspIle: 4.941 ± 0.091
3.688AspLys: 3.688 ± 0.081
6.332AspLeu: 6.332 ± 0.123
1.768AspMet: 1.768 ± 0.055
2.699AspAsn: 2.699 ± 0.082
2.245AspPro: 2.245 ± 0.132
3.443AspGln: 3.443 ± 0.085
2.646AspArg: 2.646 ± 0.072
2.903AspSer: 2.903 ± 0.075
3.252AspThr: 3.252 ± 0.067
4.332AspVal: 4.332 ± 0.077
0.62AspTrp: 0.62 ± 0.039
2.923AspTyr: 2.923 ± 0.082
0.0AspXaa: 0.0 ± 0.0
Glu
6.496GluAla: 6.496 ± 0.12
0.231GluCys: 0.231 ± 0.021
4.694GluAsp: 4.694 ± 0.087
6.241GluGlu: 6.241 ± 0.179
2.548GluPhe: 2.548 ± 0.063
4.2GluGly: 4.2 ± 0.086
1.036GluHis: 1.036 ± 0.049
5.665GluIle: 5.665 ± 0.101
4.717GluLys: 4.717 ± 0.092
5.991GluLeu: 5.991 ± 0.113
2.135GluMet: 2.135 ± 0.062
4.267GluAsn: 4.267 ± 0.095
1.913GluPro: 1.913 ± 0.131
2.574GluGln: 2.574 ± 0.064
2.888GluArg: 2.888 ± 0.084
3.749GluSer: 3.749 ± 0.094
4.088GluThr: 4.088 ± 0.105
5.187GluVal: 5.187 ± 0.099
0.628GluTrp: 0.628 ± 0.034
2.158GluTyr: 2.158 ± 0.057
0.0GluXaa: 0.0 ± 0.0
Phe
3.241PheAla: 3.241 ± 0.085
0.217PheCys: 0.217 ± 0.019
3.029PheAsp: 3.029 ± 0.084
2.993PheGlu: 2.993 ± 0.073
1.869PhePhe: 1.869 ± 0.07
3.164PheGly: 3.164 ± 0.091
0.705PheHis: 0.705 ± 0.037
3.392PheIle: 3.392 ± 0.104
2.564PheLys: 2.564 ± 0.069
3.653PheLeu: 3.653 ± 0.095
1.183PheMet: 1.183 ± 0.044
2.195PheAsn: 2.195 ± 0.066
1.456PhePro: 1.456 ± 0.054
1.675PheGln: 1.675 ± 0.062
1.384PheArg: 1.384 ± 0.053
2.728PheSer: 2.728 ± 0.07
2.578PheThr: 2.578 ± 0.071
2.963PheVal: 2.963 ± 0.078
0.403PheTrp: 0.403 ± 0.027
1.589PheTyr: 1.589 ± 0.052
0.0PheXaa: 0.0 ± 0.0
Gly
4.925GlyAla: 4.925 ± 0.119
0.312GlyCys: 0.312 ± 0.027
3.812GlyAsp: 3.812 ± 0.085
4.412GlyGlu: 4.412 ± 0.1
3.147GlyPhe: 3.147 ± 0.087
4.591GlyGly: 4.591 ± 0.113
1.411GlyHis: 1.411 ± 0.053
5.509GlyIle: 5.509 ± 0.11
4.262GlyLys: 4.262 ± 0.086
6.514GlyLeu: 6.514 ± 0.117
1.958GlyMet: 1.958 ± 0.069
2.753GlyAsn: 2.753 ± 0.076
1.656GlyPro: 1.656 ± 0.057
3.409GlyGln: 3.409 ± 0.092
2.776GlyArg: 2.776 ± 0.076
3.751GlySer: 3.751 ± 0.093
3.763GlyThr: 3.763 ± 0.083
4.984GlyVal: 4.984 ± 0.112
0.558GlyTrp: 0.558 ± 0.036
2.833GlyTyr: 2.833 ± 0.074
0.0GlyXaa: 0.0 ± 0.0
His
1.23HisAla: 1.23 ± 0.055
0.117HisCys: 0.117 ± 0.015
1.139HisAsp: 1.139 ± 0.051
1.211HisGlu: 1.211 ± 0.048
1.089HisPhe: 1.089 ± 0.047
1.309HisGly: 1.309 ± 0.047
0.572HisHis: 0.572 ± 0.04
1.411HisIle: 1.411 ± 0.053
0.924HisLys: 0.924 ± 0.049
1.759HisLeu: 1.759 ± 0.056
0.462HisMet: 0.462 ± 0.027
0.746HisAsn: 0.746 ± 0.032
1.036HisPro: 1.036 ± 0.044
0.924HisGln: 0.924 ± 0.043
0.712HisArg: 0.712 ± 0.038
1.015HisSer: 1.015 ± 0.042
1.033HisThr: 1.033 ± 0.044
1.22HisVal: 1.22 ± 0.052
0.179HisTrp: 0.179 ± 0.019
0.868HisTyr: 0.868 ± 0.035
0.0HisXaa: 0.0 ± 0.0
Ile
6.621IleAla: 6.621 ± 0.117
0.481IleCys: 0.481 ± 0.031
5.137IleAsp: 5.137 ± 0.096
5.595IleGlu: 5.595 ± 0.117
3.318IlePhe: 3.318 ± 0.079
5.362IleGly: 5.362 ± 0.114
1.489IleHis: 1.489 ± 0.054
5.588IleIle: 5.588 ± 0.12
3.786IleLys: 3.786 ± 0.076
6.831IleLeu: 6.831 ± 0.137
1.86IleMet: 1.86 ± 0.055
3.511IleAsn: 3.511 ± 0.078
2.849IlePro: 2.849 ± 0.068
3.614IleGln: 3.614 ± 0.075
2.856IleArg: 2.856 ± 0.076
4.477IleSer: 4.477 ± 0.085
4.113IleThr: 4.113 ± 0.096
5.203IleVal: 5.203 ± 0.107
0.546IleTrp: 0.546 ± 0.035
2.7IleTyr: 2.7 ± 0.084
0.0IleXaa: 0.0 ± 0.0
Lys
4.981LysAla: 4.981 ± 0.099
0.182LysCys: 0.182 ± 0.019
4.006LysAsp: 4.006 ± 0.091
4.801LysGlu: 4.801 ± 0.095
1.813LysPhe: 1.813 ± 0.058
3.679LysGly: 3.679 ± 0.079
1.069LysHis: 1.069 ± 0.043
3.861LysIle: 3.861 ± 0.08
3.908LysLys: 3.908 ± 0.106
4.683LysLeu: 4.683 ± 0.083
1.967LysMet: 1.967 ± 0.057
3.052LysAsn: 3.052 ± 0.072
1.843LysPro: 1.843 ± 0.06
2.664LysGln: 2.664 ± 0.074
2.779LysArg: 2.779 ± 0.077
3.068LysSer: 3.068 ± 0.077
3.206LysThr: 3.206 ± 0.076
4.022LysVal: 4.022 ± 0.089
0.539LysTrp: 0.539 ± 0.033
2.088LysTyr: 2.088 ± 0.066
0.0LysXaa: 0.0 ± 0.0
Leu
8.325LeuAla: 8.325 ± 0.134
0.375LeuCys: 0.375 ± 0.028
5.917LeuAsp: 5.917 ± 0.111
5.772LeuGlu: 5.772 ± 0.114
3.74LeuPhe: 3.74 ± 0.098
6.146LeuGly: 6.146 ± 0.123
1.435LeuHis: 1.435 ± 0.052
6.463LeuIle: 6.463 ± 0.121
5.347LeuLys: 5.347 ± 0.11
8.278LeuLeu: 8.278 ± 0.152
2.457LeuMet: 2.457 ± 0.075
4.755LeuAsn: 4.755 ± 0.089
3.497LeuPro: 3.497 ± 0.077
3.395LeuGln: 3.395 ± 0.086
3.351LeuArg: 3.351 ± 0.091
5.991LeuSer: 5.991 ± 0.096
5.737LeuThr: 5.737 ± 0.103
6.334LeuVal: 6.334 ± 0.107
0.653LeuTrp: 0.653 ± 0.037
2.996LeuTyr: 2.996 ± 0.07
0.0LeuXaa: 0.0 ± 0.0
Met
2.545MetAla: 2.545 ± 0.074
0.095MetCys: 0.095 ± 0.015
1.643MetAsp: 1.643 ± 0.054
1.517MetGlu: 1.517 ± 0.047
0.949MetPhe: 0.949 ± 0.043
1.717MetGly: 1.717 ± 0.062
0.471MetHis: 0.471 ± 0.025
2.056MetIle: 2.056 ± 0.054
1.813MetLys: 1.813 ± 0.049
2.016MetLeu: 2.016 ± 0.057
0.833MetMet: 0.833 ± 0.039
1.53MetAsn: 1.53 ± 0.051
1.059MetPro: 1.059 ± 0.046
1.062MetGln: 1.062 ± 0.046
1.171MetArg: 1.171 ± 0.045
1.713MetSer: 1.713 ± 0.059
2.072MetThr: 2.072 ± 0.057
2.041MetVal: 2.041 ± 0.058
0.189MetTrp: 0.189 ± 0.017
0.763MetTyr: 0.763 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
3.362AsnAla: 3.362 ± 0.084
0.212AsnCys: 0.212 ± 0.019
2.98AsnAsp: 2.98 ± 0.074
3.394AsnGlu: 3.394 ± 0.08
2.056AsnPhe: 2.056 ± 0.068
3.329AsnGly: 3.329 ± 0.094
1.201AsnHis: 1.201 ± 0.049
3.64AsnIle: 3.64 ± 0.078
2.898AsnLys: 2.898 ± 0.084
4.246AsnLeu: 4.246 ± 0.093
1.325AsnMet: 1.325 ± 0.048
2.483AsnAsn: 2.483 ± 0.091
2.126AsnPro: 2.126 ± 0.068
2.816AsnGln: 2.816 ± 0.081
2.329AsnArg: 2.329 ± 0.06
2.09AsnSer: 2.09 ± 0.058
2.422AsnThr: 2.422 ± 0.075
3.096AsnVal: 3.096 ± 0.074
0.52AsnTrp: 0.52 ± 0.036
1.95AsnTyr: 1.95 ± 0.064
0.0AsnXaa: 0.0 ± 0.0
Pro
2.469ProAla: 2.469 ± 0.085
0.13ProCys: 0.13 ± 0.015
2.317ProAsp: 2.317 ± 0.07
3.033ProGlu: 3.033 ± 0.142
1.652ProPhe: 1.652 ± 0.055
2.242ProGly: 2.242 ± 0.067
0.599ProHis: 0.599 ± 0.036
2.63ProIle: 2.63 ± 0.069
1.834ProLys: 1.834 ± 0.054
2.856ProLeu: 2.856 ± 0.064
0.856ProMet: 0.856 ± 0.039
1.803ProAsn: 1.803 ± 0.056
0.581ProPro: 0.581 ± 0.03
1.103ProGln: 1.103 ± 0.044
1.055ProArg: 1.055 ± 0.044
2.158ProSer: 2.158 ± 0.065
2.133ProThr: 2.133 ± 0.087
2.772ProVal: 2.772 ± 0.102
0.287ProTrp: 0.287 ± 0.021
1.43ProTyr: 1.43 ± 0.054
0.0ProXaa: 0.0 ± 0.0
Gln
4.465GlnAla: 4.465 ± 0.113
0.124GlnCys: 0.124 ± 0.017
2.501GlnAsp: 2.501 ± 0.067
3.134GlnGlu: 3.134 ± 0.088
1.752GlnPhe: 1.752 ± 0.054
2.371GlnGly: 2.371 ± 0.06
0.7GlnHis: 0.7 ± 0.035
3.059GlnIle: 3.059 ± 0.076
2.249GlnLys: 2.249 ± 0.069
4.225GlnLeu: 4.225 ± 0.115
1.257GlnMet: 1.257 ± 0.044
2.013GlnAsn: 2.013 ± 0.06
1.432GlnPro: 1.432 ± 0.057
1.815GlnGln: 1.815 ± 0.068
1.661GlnArg: 1.661 ± 0.061
2.471GlnSer: 2.471 ± 0.059
2.431GlnThr: 2.431 ± 0.068
3.717GlnVal: 3.717 ± 0.098
0.364GlnTrp: 0.364 ± 0.026
1.607GlnTyr: 1.607 ± 0.058
0.0GlnXaa: 0.0 ± 0.0
Arg
2.646ArgAla: 2.646 ± 0.078
0.142ArgCys: 0.142 ± 0.015
2.427ArgAsp: 2.427 ± 0.071
2.721ArgGlu: 2.721 ± 0.065
1.866ArgPhe: 1.866 ± 0.063
2.321ArgGly: 2.321 ± 0.071
0.795ArgHis: 0.795 ± 0.042
3.098ArgIle: 3.098 ± 0.084
2.543ArgLys: 2.543 ± 0.067
3.822ArgLeu: 3.822 ± 0.084
1.129ArgMet: 1.129 ± 0.043
1.855ArgAsn: 1.855 ± 0.065
1.472ArgPro: 1.472 ± 0.061
2.053ArgGln: 2.053 ± 0.069
1.937ArgArg: 1.937 ± 0.069
1.967ArgSer: 1.967 ± 0.063
1.988ArgThr: 1.988 ± 0.049
2.783ArgVal: 2.783 ± 0.067
0.329ArgTrp: 0.329 ± 0.023
1.577ArgTyr: 1.577 ± 0.053
0.0ArgXaa: 0.0 ± 0.0
Ser
4.199SerAla: 4.199 ± 0.112
0.198SerCys: 0.198 ± 0.021
3.551SerAsp: 3.551 ± 0.088
4.104SerGlu: 4.104 ± 0.114
2.653SerPhe: 2.653 ± 0.082
4.484SerGly: 4.484 ± 0.101
1.071SerHis: 1.071 ± 0.039
4.241SerIle: 4.241 ± 0.092
3.252SerLys: 3.252 ± 0.079
5.357SerLeu: 5.357 ± 0.091
1.428SerMet: 1.428 ± 0.051
2.672SerAsn: 2.672 ± 0.069
1.817SerPro: 1.817 ± 0.067
2.611SerGln: 2.611 ± 0.083
2.305SerArg: 2.305 ± 0.065
3.852SerSer: 3.852 ± 0.185
3.217SerThr: 3.217 ± 0.082
3.912SerVal: 3.912 ± 0.086
0.532SerTrp: 0.532 ± 0.031
2.149SerTyr: 2.149 ± 0.066
0.0SerXaa: 0.0 ± 0.0
Thr
4.57ThrAla: 4.57 ± 0.096
0.249ThrCys: 0.249 ± 0.022
3.719ThrAsp: 3.719 ± 0.114
3.681ThrGlu: 3.681 ± 0.085
2.643ThrPhe: 2.643 ± 0.073
4.272ThrGly: 4.272 ± 0.076
1.057ThrHis: 1.057 ± 0.041
4.808ThrIle: 4.808 ± 0.075
2.963ThrLys: 2.963 ± 0.071
5.205ThrLeu: 5.205 ± 0.102
1.377ThrMet: 1.377 ± 0.054
2.618ThrAsn: 2.618 ± 0.081
2.284ThrPro: 2.284 ± 0.062
1.901ThrGln: 1.901 ± 0.056
1.927ThrArg: 1.927 ± 0.061
3.539ThrSer: 3.539 ± 0.092
3.513ThrThr: 3.513 ± 0.089
4.251ThrVal: 4.251 ± 0.101
0.513ThrTrp: 0.513 ± 0.037
2.371ThrTyr: 2.371 ± 0.08
0.0ThrXaa: 0.0 ± 0.0
Val
6.486ValAla: 6.486 ± 0.13
0.329ValCys: 0.329 ± 0.024
4.874ValAsp: 4.874 ± 0.097
5.061ValGlu: 5.061 ± 0.103
2.8ValPhe: 2.8 ± 0.081
4.816ValGly: 4.816 ± 0.1
1.26ValHis: 1.26 ± 0.052
5.324ValIle: 5.324 ± 0.112
3.957ValLys: 3.957 ± 0.1
6.304ValLeu: 6.304 ± 0.124
1.916ValMet: 1.916 ± 0.066
3.274ValAsn: 3.274 ± 0.086
2.529ValPro: 2.529 ± 0.058
2.406ValGln: 2.406 ± 0.063
2.539ValArg: 2.539 ± 0.065
4.435ValSer: 4.435 ± 0.092
4.37ValThr: 4.37 ± 0.103
5.329ValVal: 5.329 ± 0.104
0.558ValTrp: 0.558 ± 0.032
2.452ValTyr: 2.452 ± 0.066
0.0ValXaa: 0.0 ± 0.0
Trp
0.571TrpAla: 0.571 ± 0.025
0.039TrpCys: 0.039 ± 0.007
0.513TrpAsp: 0.513 ± 0.038
0.487TrpGlu: 0.487 ± 0.029
0.411TrpPhe: 0.411 ± 0.028
0.481TrpGly: 0.481 ± 0.031
0.214TrpHis: 0.214 ± 0.019
0.613TrpIle: 0.613 ± 0.034
0.373TrpLys: 0.373 ± 0.025
0.984TrpLeu: 0.984 ± 0.046
0.207TrpMet: 0.207 ± 0.017
0.354TrpAsn: 0.354 ± 0.026
0.249TrpPro: 0.249 ± 0.023
0.546TrpGln: 0.546 ± 0.031
0.415TrpArg: 0.415 ± 0.025
0.49TrpSer: 0.49 ± 0.025
0.551TrpThr: 0.551 ± 0.046
0.583TrpVal: 0.583 ± 0.029
0.098TrpTrp: 0.098 ± 0.013
0.299TrpTyr: 0.299 ± 0.026
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.693TyrAla: 2.693 ± 0.079
0.217TyrCys: 0.217 ± 0.022
2.342TyrAsp: 2.342 ± 0.061
2.373TyrGlu: 2.373 ± 0.073
1.846TyrPhe: 1.846 ± 0.058
2.531TyrGly: 2.531 ± 0.067
0.91TyrHis: 0.91 ± 0.037
2.62TyrIle: 2.62 ± 0.085
1.909TyrLys: 1.909 ± 0.063
3.812TyrLeu: 3.812 ± 0.085
0.866TyrMet: 0.866 ± 0.038
1.713TyrAsn: 1.713 ± 0.063
1.545TyrPro: 1.545 ± 0.055
2.132TyrGln: 2.132 ± 0.063
1.64TyrArg: 1.64 ± 0.061
2.006TyrSer: 2.006 ± 0.058
2.23TyrThr: 2.23 ± 0.073
2.301TyrVal: 2.301 ± 0.062
0.343TyrTrp: 0.343 ± 0.027
1.554TyrTyr: 1.554 ± 0.06
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1929 proteins (571387 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski