Amino acid dipepetide frequency for Aquitalea magnusonii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.991AlaAla: 14.991 ± 0.163	1.322AlaCys: 1.322 ± 0.037	6.46AlaAsp: 6.46 ± 0.085	6.634AlaGlu: 6.634 ± 0.095	3.648AlaPhe: 3.648 ± 0.057	9.612AlaGly: 9.612 ± 0.084	2.254AlaHis: 2.254 ± 0.05	5.767AlaIle: 5.767 ± 0.069	3.491AlaLys: 3.491 ± 0.066	13.199AlaLeu: 13.199 ± 0.118	3.602AlaMet: 3.602 ± 0.06	3.07AlaAsn: 3.07 ± 0.048	4.168AlaPro: 4.168 ± 0.071	5.011AlaGln: 5.011 ± 0.061	7.601AlaArg: 7.601 ± 0.095	7.005AlaSer: 7.005 ± 0.082	5.121AlaThr: 5.121 ± 0.07	7.801AlaVal: 7.801 ± 0.087	1.62AlaTrp: 1.62 ± 0.041	2.513AlaTyr: 2.513 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.022CysAla: 1.022 ± 0.029	0.173CysCys: 0.173 ± 0.013	0.539CysAsp: 0.539 ± 0.022	0.473CysGlu: 0.473 ± 0.019	0.355CysPhe: 0.355 ± 0.017	1.043CysGly: 1.043 ± 0.031	0.374CysHis: 0.374 ± 0.016	0.458CysIle: 0.458 ± 0.02	0.285CysLys: 0.285 ± 0.017	1.173CysLeu: 1.173 ± 0.038	0.23CysMet: 0.23 ± 0.013	0.313CysAsn: 0.313 ± 0.017	0.555CysPro: 0.555 ± 0.022	0.537CysGln: 0.537 ± 0.021	0.669CysArg: 0.669 ± 0.021	0.625CysSer: 0.625 ± 0.024	0.485CysThr: 0.485 ± 0.019	0.652CysVal: 0.652 ± 0.023	0.172CysTrp: 0.172 ± 0.012	0.309CysTyr: 0.309 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	5.937AspAla: 5.937 ± 0.093	0.595AspCys: 0.595 ± 0.023	2.644AspAsp: 2.644 ± 0.052	3.065AspGlu: 3.065 ± 0.054	2.152AspPhe: 2.152 ± 0.043	4.395AspGly: 4.395 ± 0.073	1.102AspHis: 1.102 ± 0.031	3.233AspIle: 3.233 ± 0.043	2.22AspLys: 2.22 ± 0.047	4.9AspLeu: 4.9 ± 0.067	1.48AspMet: 1.48 ± 0.035	1.548AspAsn: 1.548 ± 0.039	2.421AspPro: 2.421 ± 0.05	1.803AspGln: 1.803 ± 0.034	2.611AspArg: 2.611 ± 0.05	3.015AspSer: 3.015 ± 0.053	2.491AspThr: 2.491 ± 0.041	3.681AspVal: 3.681 ± 0.055	1.022AspTrp: 1.022 ± 0.03	1.698AspTyr: 1.698 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	6.17GluAla: 6.17 ± 0.086	0.424GluCys: 0.424 ± 0.016	2.358GluAsp: 2.358 ± 0.045	2.839GluGlu: 2.839 ± 0.059	1.707GluPhe: 1.707 ± 0.038	3.247GluGly: 3.247 ± 0.056	1.408GluHis: 1.408 ± 0.032	2.808GluIle: 2.808 ± 0.055	2.179GluLys: 2.179 ± 0.047	6.113GluLeu: 6.113 ± 0.075	1.4GluMet: 1.4 ± 0.038	1.554GluAsn: 1.554 ± 0.034	1.912GluPro: 1.912 ± 0.043	3.383GluGln: 3.383 ± 0.059	3.706GluArg: 3.706 ± 0.056	2.515GluSer: 2.515 ± 0.043	2.46GluThr: 2.46 ± 0.051	3.92GluVal: 3.92 ± 0.065	0.731GluTrp: 0.731 ± 0.026	1.156GluTyr: 1.156 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	4.193PheAla: 4.193 ± 0.066	0.458PheCys: 0.458 ± 0.017	2.446PheAsp: 2.446 ± 0.045	1.762PheGlu: 1.762 ± 0.043	1.432PhePhe: 1.432 ± 0.041	3.167PheGly: 3.167 ± 0.052	0.87PheHis: 0.87 ± 0.028	1.902PheIle: 1.902 ± 0.043	1.201PheLys: 1.201 ± 0.031	3.169PheLeu: 3.169 ± 0.063	0.911PheMet: 0.911 ± 0.028	1.313PheAsn: 1.313 ± 0.036	1.462PhePro: 1.462 ± 0.037	1.179PheGln: 1.179 ± 0.031	1.806PheArg: 1.806 ± 0.041	2.418PheSer: 2.418 ± 0.045	1.848PheThr: 1.848 ± 0.043	2.608PheVal: 2.608 ± 0.045	0.566PheTrp: 0.566 ± 0.026	1.053PheTyr: 1.053 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	6.466GlyAla: 6.466 ± 0.079	0.981GlyCys: 0.981 ± 0.026	3.51GlyAsp: 3.51 ± 0.053	4.272GlyGlu: 4.272 ± 0.062	3.367GlyPhe: 3.367 ± 0.055	5.855GlyGly: 5.855 ± 0.093	1.957GlyHis: 1.957 ± 0.041	4.377GlyIle: 4.377 ± 0.069	3.889GlyLys: 3.889 ± 0.065	8.902GlyLeu: 8.902 ± 0.093	2.566GlyMet: 2.566 ± 0.044	2.541GlyAsn: 2.541 ± 0.056	2.317GlyPro: 2.317 ± 0.042	3.786GlyGln: 3.786 ± 0.057	4.695GlyArg: 4.695 ± 0.068	5.004GlySer: 5.004 ± 0.078	3.261GlyThr: 3.261 ± 0.054	5.969GlyVal: 5.969 ± 0.07	1.43GlyTrp: 1.43 ± 0.038	2.318GlyTyr: 2.318 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.706HisAla: 2.706 ± 0.047	0.334HisCys: 0.334 ± 0.017	1.321HisAsp: 1.321 ± 0.037	1.112HisGlu: 1.112 ± 0.033	1.011HisPhe: 1.011 ± 0.031	2.332HisGly: 2.332 ± 0.05	0.773HisHis: 0.773 ± 0.036	1.21HisIle: 1.21 ± 0.028	0.658HisLys: 0.658 ± 0.02	2.3HisLeu: 2.3 ± 0.046	0.591HisMet: 0.591 ± 0.021	0.665HisAsn: 0.665 ± 0.023	1.529HisPro: 1.529 ± 0.035	1.164HisGln: 1.164 ± 0.031	1.219HisArg: 1.219 ± 0.032	1.336HisSer: 1.336 ± 0.033	1.141HisThr: 1.141 ± 0.031	1.548HisVal: 1.548 ± 0.035	0.487HisTrp: 0.487 ± 0.022	0.851HisTyr: 0.851 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.089IleAla: 6.089 ± 0.079	0.536IleCys: 0.536 ± 0.024	3.0IleAsp: 3.0 ± 0.049	2.744IleGlu: 2.744 ± 0.052	1.479IlePhe: 1.479 ± 0.036	4.262IleGly: 4.262 ± 0.073	1.103IleHis: 1.103 ± 0.027	2.327IleIle: 2.327 ± 0.045	1.943IleLys: 1.943 ± 0.042	4.275IleLeu: 4.275 ± 0.072	1.033IleMet: 1.033 ± 0.027	1.873IleAsn: 1.873 ± 0.043	2.327IlePro: 2.327 ± 0.046	1.643IleGln: 1.643 ± 0.039	3.112IleArg: 3.112 ± 0.046	3.353IleSer: 3.353 ± 0.059	2.767IleThr: 2.767 ± 0.046	3.438IleVal: 3.438 ± 0.054	0.549IleTrp: 0.549 ± 0.02	1.136IleTyr: 1.136 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.934LysAla: 3.934 ± 0.064	0.191LysCys: 0.191 ± 0.014	1.676LysAsp: 1.676 ± 0.035	1.73LysGlu: 1.73 ± 0.045	0.901LysPhe: 0.901 ± 0.026	2.464LysGly: 2.464 ± 0.051	0.796LysHis: 0.796 ± 0.024	1.657LysIle: 1.657 ± 0.036	1.628LysLys: 1.628 ± 0.045	4.395LysLeu: 4.395 ± 0.068	0.936LysMet: 0.936 ± 0.026	1.158LysAsn: 1.158 ± 0.029	2.163LysPro: 2.163 ± 0.049	1.989LysGln: 1.989 ± 0.039	2.145LysArg: 2.145 ± 0.046	1.878LysSer: 1.878 ± 0.037	1.96LysThr: 1.96 ± 0.04	2.788LysVal: 2.788 ± 0.048	0.37LysTrp: 0.37 ± 0.017	0.789LysTyr: 0.789 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	15.173LeuAla: 15.173 ± 0.141	1.229LeuCys: 1.229 ± 0.033	6.24LeuAsp: 6.24 ± 0.082	5.756LeuGlu: 5.756 ± 0.075	4.023LeuPhe: 4.023 ± 0.075	8.551LeuGly: 8.551 ± 0.087	2.67LeuHis: 2.67 ± 0.054	5.008LeuIle: 5.008 ± 0.063	4.002LeuLys: 4.002 ± 0.062	14.265LeuLeu: 14.265 ± 0.191	2.739LeuMet: 2.739 ± 0.051	3.312LeuAsn: 3.312 ± 0.055	6.796LeuPro: 6.796 ± 0.085	5.955LeuGln: 5.955 ± 0.083	6.564LeuArg: 6.564 ± 0.081	7.612LeuSer: 7.612 ± 0.09	5.7LeuThr: 5.7 ± 0.069	7.313LeuVal: 7.313 ± 0.093	1.362LeuTrp: 1.362 ± 0.038	2.439LeuTyr: 2.439 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	3.196MetAla: 3.196 ± 0.055	0.207MetCys: 0.207 ± 0.014	1.211MetAsp: 1.211 ± 0.033	1.177MetGlu: 1.177 ± 0.034	0.723MetPhe: 0.723 ± 0.027	1.886MetGly: 1.886 ± 0.042	0.63MetHis: 0.63 ± 0.02	1.095MetIle: 1.095 ± 0.032	1.102MetLys: 1.102 ± 0.029	3.435MetLeu: 3.435 ± 0.062	0.653MetMet: 0.653 ± 0.024	0.861MetAsn: 0.861 ± 0.025	1.417MetPro: 1.417 ± 0.039	1.512MetGln: 1.512 ± 0.035	1.484MetArg: 1.484 ± 0.032	1.794MetSer: 1.794 ± 0.042	1.482MetThr: 1.482 ± 0.033	1.845MetVal: 1.845 ± 0.036	0.242MetTrp: 0.242 ± 0.012	0.426MetTyr: 0.426 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.188AsnAla: 3.188 ± 0.047	0.311AsnCys: 0.311 ± 0.016	1.465AsnAsp: 1.465 ± 0.037	1.277AsnGlu: 1.277 ± 0.03	0.905AsnPhe: 0.905 ± 0.03	2.499AsnGly: 2.499 ± 0.054	0.67AsnHis: 0.67 ± 0.02	1.576AsnIle: 1.576 ± 0.042	1.134AsnLys: 1.134 ± 0.033	3.183AsnLeu: 3.183 ± 0.051	0.745AsnMet: 0.745 ± 0.025	1.0AsnAsn: 1.0 ± 0.035	1.977AsnPro: 1.977 ± 0.037	1.359AsnGln: 1.359 ± 0.036	1.838AsnArg: 1.838 ± 0.04	1.71AsnSer: 1.71 ± 0.045	1.641AsnThr: 1.641 ± 0.039	2.02AsnVal: 2.02 ± 0.04	0.484AsnTrp: 0.484 ± 0.02	0.824AsnTyr: 0.824 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	6.284ProAla: 6.284 ± 0.085	0.425ProCys: 0.425 ± 0.02	3.092ProAsp: 3.092 ± 0.053	2.953ProGlu: 2.953 ± 0.052	1.769ProPhe: 1.769 ± 0.036	3.705ProGly: 3.705 ± 0.059	1.106ProHis: 1.106 ± 0.033	1.762ProIle: 1.762 ± 0.037	1.318ProLys: 1.318 ± 0.037	5.452ProLeu: 5.452 ± 0.076	1.11ProMet: 1.11 ± 0.029	1.162ProAsn: 1.162 ± 0.033	1.981ProPro: 1.981 ± 0.046	2.434ProGln: 2.434 ± 0.052	2.322ProArg: 2.322 ± 0.046	2.376ProSer: 2.376 ± 0.048	2.004ProThr: 2.004 ± 0.042	3.9ProVal: 3.9 ± 0.06	0.724ProTrp: 0.724 ± 0.022	1.225ProTyr: 1.225 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	6.372GlnAla: 6.372 ± 0.093	0.38GlnCys: 0.38 ± 0.017	2.212GlnAsp: 2.212 ± 0.043	2.098GlnGlu: 2.098 ± 0.04	1.495GlnPhe: 1.495 ± 0.036	3.633GlnGly: 3.633 ± 0.058	1.569GlnHis: 1.569 ± 0.036	2.097GlnIle: 2.097 ± 0.043	1.303GlnLys: 1.303 ± 0.034	6.668GlnLeu: 6.668 ± 0.093	1.18GlnMet: 1.18 ± 0.033	1.134GlnAsn: 1.134 ± 0.028	2.607GlnPro: 2.607 ± 0.058	4.2GlnGln: 4.2 ± 0.092	3.425GlnArg: 3.425 ± 0.052	2.46GlnSer: 2.46 ± 0.043	2.149GlnThr: 2.149 ± 0.046	3.236GlnVal: 3.236 ± 0.053	0.775GlnTrp: 0.775 ± 0.027	1.141GlnTyr: 1.141 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	5.533ArgAla: 5.533 ± 0.071	0.56ArgCys: 0.56 ± 0.022	3.136ArgAsp: 3.136 ± 0.051	3.634ArgGlu: 3.634 ± 0.062	2.775ArgPhe: 2.775 ± 0.051	3.51ArgGly: 3.51 ± 0.05	1.883ArgHis: 1.883 ± 0.044	3.34ArgIle: 3.34 ± 0.055	2.26ArgLys: 2.26 ± 0.042	7.705ArgLeu: 7.705 ± 0.096	1.671ArgMet: 1.671 ± 0.038	1.806ArgAsn: 1.806 ± 0.038	2.547ArgPro: 2.547 ± 0.043	3.956ArgGln: 3.956 ± 0.053	3.976ArgArg: 3.976 ± 0.069	3.118ArgSer: 3.118 ± 0.049	2.417ArgThr: 2.417 ± 0.042	3.995ArgVal: 3.995 ± 0.059	0.958ArgTrp: 0.958 ± 0.031	1.944ArgTyr: 1.944 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	6.241SerAla: 6.241 ± 0.076	0.63SerCys: 0.63 ± 0.025	2.663SerAsp: 2.663 ± 0.048	2.637SerGlu: 2.637 ± 0.05	2.255SerPhe: 2.255 ± 0.036	5.378SerGly: 5.378 ± 0.07	1.546SerHis: 1.546 ± 0.036	2.902SerIle: 2.902 ± 0.055	2.043SerLys: 2.043 ± 0.048	7.032SerLeu: 7.032 ± 0.09	1.598SerMet: 1.598 ± 0.033	1.854SerAsn: 1.854 ± 0.043	2.861SerPro: 2.861 ± 0.042	2.789SerGln: 2.789 ± 0.056	3.724SerArg: 3.724 ± 0.057	3.776SerSer: 3.776 ± 0.07	3.14SerThr: 3.14 ± 0.063	3.954SerVal: 3.954 ± 0.055	0.877SerTrp: 0.877 ± 0.03	1.65SerTyr: 1.65 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.562ThrAla: 5.562 ± 0.076	0.412ThrCys: 0.412 ± 0.018	2.248ThrAsp: 2.248 ± 0.046	2.193ThrGlu: 2.193 ± 0.05	1.561ThrPhe: 1.561 ± 0.042	4.111ThrGly: 4.111 ± 0.062	1.109ThrHis: 1.109 ± 0.03	2.279ThrIle: 2.279 ± 0.043	1.092ThrLys: 1.092 ± 0.032	6.482ThrLeu: 6.482 ± 0.083	1.082ThrMet: 1.082 ± 0.035	1.215ThrAsn: 1.215 ± 0.036	3.023ThrPro: 3.023 ± 0.049	1.88ThrGln: 1.88 ± 0.038	2.91ThrArg: 2.91 ± 0.048	2.679ThrSer: 2.679 ± 0.05	2.573ThrThr: 2.573 ± 0.056	4.025ThrVal: 4.025 ± 0.065	0.469ThrTrp: 0.469 ± 0.02	0.961ThrTyr: 0.961 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	8.193ValAla: 8.193 ± 0.092	0.796ValCys: 0.796 ± 0.029	3.88ValAsp: 3.88 ± 0.062	4.101ValGlu: 4.101 ± 0.058	2.644ValPhe: 2.644 ± 0.052	4.929ValGly: 4.929 ± 0.073	1.392ValHis: 1.392 ± 0.035	3.641ValIle: 3.641 ± 0.06	2.585ValLys: 2.585 ± 0.058	8.459ValLeu: 8.459 ± 0.106	1.97ValMet: 1.97 ± 0.039	2.267ValAsn: 2.267 ± 0.049	2.93ValPro: 2.93 ± 0.052	2.711ValGln: 2.711 ± 0.051	4.007ValArg: 4.007 ± 0.056	4.64ValSer: 4.64 ± 0.061	3.404ValThr: 3.404 ± 0.057	5.644ValVal: 5.644 ± 0.078	0.884ValTrp: 0.884 ± 0.029	1.698ValTyr: 1.698 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.064TrpAla: 1.064 ± 0.034	0.182TrpCys: 0.182 ± 0.012	0.564TrpAsp: 0.564 ± 0.023	0.543TrpGlu: 0.543 ± 0.02	0.519TrpPhe: 0.519 ± 0.02	0.858TrpGly: 0.858 ± 0.027	0.43TrpHis: 0.43 ± 0.022	0.585TrpIle: 0.585 ± 0.02	0.474TrpLys: 0.474 ± 0.02	2.577TrpLeu: 2.577 ± 0.059	0.401TrpMet: 0.401 ± 0.02	0.408TrpAsn: 0.408 ± 0.018	0.695TrpPro: 0.695 ± 0.029	1.277TrpGln: 1.277 ± 0.037	1.042TrpArg: 1.042 ± 0.031	0.775TrpSer: 0.775 ± 0.026	0.547TrpThr: 0.547 ± 0.022	0.887TrpVal: 0.887 ± 0.027	0.267TrpTrp: 0.267 ± 0.018	0.316TrpTyr: 0.316 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.578TyrAla: 2.578 ± 0.051	0.299TyrCys: 0.299 ± 0.014	1.349TyrAsp: 1.349 ± 0.066	0.989TyrGlu: 0.989 ± 0.032	1.039TyrPhe: 1.039 ± 0.028	2.027TyrGly: 2.027 ± 0.041	0.648TyrHis: 0.648 ± 0.022	0.962TyrIle: 0.962 ± 0.031	0.743TyrLys: 0.743 ± 0.026	3.026TyrLeu: 3.026 ± 0.052	0.48TyrMet: 0.48 ± 0.019	0.757TyrAsn: 0.757 ± 0.026	1.413TyrPro: 1.413 ± 0.035	1.565TyrGln: 1.565 ± 0.03	1.866TyrArg: 1.866 ± 0.041	1.46TyrSer: 1.46 ± 0.039	1.275TyrThr: 1.275 ± 0.032	1.553TyrVal: 1.553 ± 0.037	0.42TyrTrp: 0.42 ± 0.019	0.7TyrTyr: 0.7 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4103 proteins (1282727 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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